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Hattori Yuichi  服部 裕一

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HATTORI Yuichi  服部 裕一

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Researcher Number 50156361
Other IDs
External Links
Affiliation (Current) 2025: 北海道医療大学, その他, 客員教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 北海道医療大学, その他, 客員教授
2011 – 2021: 富山大学, 大学院医学薬学研究部(医学), 教授
2019: 北海道医療大学, その他, 客員教授
2009 – 2011: 富山大学, 大学院・医学薬学研究部(医学), 教授
2010: 富山大学, 医学薬学研究部, 教授 … More
2008 – 2010: University of Toyama, 医学薬学研究部(医学), 教授
2007: University of Toyama, Pharmacology, Professor
2006 – 2007: University of Toyama, School of Medicine, Department of Pharmacology, Professor, 医学薬学研究部, 教授
2006: 富山大学, 大学院医学薬学研究部, 教授
2005: 富山医科薬科大学, 医学部, 教授
2005: Univ.of Toyama, School of Med., Prof., 医学部, 教授
2004: 北海道大学, 医学系研究科, 助教授
2000 – 2004: Hokkaido Univ., Grad.School of Med., As.Prof, 大学院・医学研究科, 助教授
2002: 北海道大学, 大学院・医学研究科, 教授
1995 – 1999: 北海道大学, 医学部, 助教授
1992: Hokkaido Univ. Sch. of Med.,, 医学部, 助教授
1991: 北海道大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General pharmacology / General pharmacology / Anesthesiology/Resuscitation studies / Obstetrics and gynecology
Except Principal Investigator
General pharmacology / Basic Section 55060:Emergency medicine-related / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Anesthesiology / Gastroenterology … More / Emergency medicine / General pharmacology / Circulatory organs internal medicine / Applied pharmacology / Obstetrics and gynecology / Science and Engineering Less
Keywords
Principal Investigator
敗血症 / 急性肺傷害 / FADD / アポトーシス / 転写因子 / -3 / 内皮由来NO合成酵素 / NCX1 mRNA / 心筋細胞 / 陽性変力作用 … More / Endothelin-1 / 炎症性サイトカイン / 遺伝子治療 / caspase-3 / eNOS / 転与因子 / 薬理学 / 播種性血管内凝固 / Small interfering RNA(siRNA) / Caspase-8 / Acute lung injury / Endothelial cells / Apoptosis / RNA interference / Sepsis / 短鎖干渉RNA (siRNA) / RNA千渉 / 短鎖干渉RNA(siRNA) / caspase-8 / 血管内皮 / RNA干渉 / rabbit ear artery / free radical scavenger / endothelial nitric oxide synthase / endothelium-dependent relaxation / irradiation / 血管内皮細胞 / Edaravone / ウサギ耳動脈 / フリーラジカルスカベンジャー / 内皮依存性弛緩反応 / 放射線照射 / NCX1 protein / [CaィイD12+ィエD1]ィイD2iィエD2 / NaィイD1+ィエD1-CaィイD12+ィエD1 exhange / Cardiomyocyte / Diabetes / NCX1mRNA / NCX1タンパク / 細胞内Ca^<2+>濃度 / Na^+-Ca^<2+>交換系 / 糖尿病 / Cardiac muscle / Tyrosine phosphorylation / Tyrosine kinase inhibitors / Positive inotropic effect / H_1-receptors / Histamine / アンキオランシン / アンギオテンシン / カルシウム電流 / チロシンキナーゼ / チロシンリン酸化 / チロシンキナーゼ阻害剤 / 陽性変力効果 / H_1-受容体 / ヒスタミン / Guinea pig left atria / Action potential / Positive inotropism / Phosphoinositide hydrolysis / Protein kinase C / Endothelinー1 / CーKinase / Phosphoinositide水解 / モルモット左心房 / 活動電位 / イノシトールリン脂質代謝回転 / C-Kinase / β-Arrestin2 / iNOS / ミクログリア / 敗血症性脳症 / 活性酸素 / GRK2 / SIRT1 / レスベラトロール / エピジェネティックス / 脱アセチル化酵素 / エピジェネティクス / 販血症 / siRNA / デコイ核酸 / 炎症・免疫 / 吸入療法 / 炎症性分子 / ステロイド / 転写因子NF-κB / 急性肺障害 / Akt / KDR / VEGF / 脳毛細血管 / 遺伝子改変マウス / エストロゲン受容体 … More
Except Principal Investigator
敗血症 / sepsis / 炎症 / 多臓器不全 / 遺伝子治療 / 転写因子 / 心機能 / Toll-like receptor / MyD88 / GST pull-down / heart / 細胞内情報伝達 / G蛋白 / Toll-like受容体 / NF-κB / Ca^<2+> uptake / Vascular smooth muscle cell / cDNAクローニング / カルシウム取り込み / アフリカツメガエル卵母細胞 / 収縮 / 血管平滑筋 / エンドセリン / 陽性変力作用 / NO / β受容体 / 細胞委縮変形像 / ラジカルスカベンジャー / 酸化ストレス / トランスクリプトーム / トランスクリプトーム解析 / 細胞死 / 全身性炎症 / 核酸医薬 / 敗血症 多臓器不全 / 多臓器障害 / STAT-3 / JAK2 / IL-6 / 炎症性サイトカイン / STAT3 / 生理学 / 薬理学 / Caチャネル / 心筋細胞Ca動態 / 敗血症モデルマウス / Na/Ca交換電流 / patch clamp / Na/Ca exchanger (NCX) / マウス敗血症モデル / 心筋Ca動態 / パッチクランプ法 / 心室筋細胞 / Na/Ca交換輸送体 / 腸管上皮細胞 / がん細胞 / 亜鉛 / 悪性腫瘍 / 大腸がん / 腸上皮細胞 / 亜鉛トランスポーター / リボシメンダン / 心筋細胞 / アデニール酸シクラーゼ / 心筋 / ドブタミン / PDE4 / ホスホジエステラーゼ / ATP sensitive K channel / Volatile anesthetics / Arrhythmias / Cardiac function / Brain death / 麻酔薬 / ATP感受性Kチャンネル / 揮発性麻酔薬 / 不整脈 / 脳死 / MODS / NF-kB / 遺伝子発現 / TRAF6 / slide attack 理論 / cDNA cloning / yeast two-hybrid / Xenopus oocyte / Ca^<2+> channel / Endothelin receptor / 受容体作動性カルシウムチャネル / _CDNAクローニング / 酵母two-hybrid / カルシウムチャネル / エンドセリン受容体 / knockout mice / gene therapy / nuclear factor-κB / Gs-α / 盲腸結紮モデル / 心筋陽性変力作用 / 敗血症性ショック / TNF-a / nuclear factor κB / macrophage migration inhibitory factor / 遺伝子欠損動物 / Gsα蛋白 / 心収縮性 / 遺伝子改変動物 / Gsαタンパク / 心臓 / Xenopus oocytes / Expression cloning / Voltage-independent Ca^<2+> channels / Vascular contraction / Endothelin / ショ糖密度勾配超遠心 / ボルテージクランプ / ^<45>Ca^<2+>取り込み / カルシウムチャンネル / 発現クローニング / 卵母細胞 / 受容体作動性カルシウムチャンネル / CDNAクローニング / 受容体作動性カルシュムチャネル / G protein / adnylate cyclase / intracellular signal thansduction pathway / beta-receptor / shock / NO(一酸化窒素) / G蛋白質 / アデニレートシクラーゼ / 細胞内情報伝達系 / ショック / ACE inhibitor / CaィイD12+ィエD1 sensitivity / intracellular CaィイD12+ィエD1 handling / myocardial infarction / congestive heart failure / 細胞内Ca^<2+>ハンドリング / ACE阻害薬 / Ca^<2+>感受性 / 細胞内Ca^<2+>トハンドリング / 心筋梗塞 / 心不全 / 高グルコース / ルシゲニン / HMGB1 / 高濃度グルコース / 活性酸素 / 酸化/ニトロ化ストレス / NADPH oxidase / 再生医療 / 骨髄由来多能性前駆細胞 / 組織再生 / 薬物治療学 / 核委縮 / 核濃染色 / スタチン / リモデリング / 細胞萎縮変形像 / 細胞濃染色像 / PI3K-Akt / インスリンシグナル / NADPH oxidase活性 / インスリン作用不全 / Akt / ニトロ化ストレス / 免疫 / アポトーシス / 卵巣摘出 / eNOS / VEGF / 脳血管 / 冠動脈 / ラット / エストロゲン / チトクロームP450 / 内皮由来弛緩因子 / 血管平滑筋細胞 / 血管内皮細胞 / コネキシン / ラット腸管膜動脈 / ギャップジャンクション / Kチャネル / 内皮由来過分極因子 Less
  • Research Projects

    (28 results)
  • Research Products

    (198 results)
  • Co-Researchers

    (23 People)
  •  Transcriptome analysis and drug discovery in sepsis

    • Principal Investigator
      松田 直之
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Nagoya University
  •  Medical innovation using gene therapy of transcriptional factor STAT3 in septic multiple organ dysfunction

    • Principal Investigator
      Naoyuki Matsuda
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Nagoya University
  •  Prophylactic and therapeutic strategy based on the molecular pathology of septic disseminated intravascular coagulation (DIC)Principal Investigator

    • Principal Investigator
      HATTORI Yuichi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Health Sciences University of Hokkaido
      University of Toyama
  •  Studies of Zinc transporter detected in tumor lesions as a target for cancer therapy

    • Principal Investigator
      Ohashi Wakana
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Toyama
  •  Analysis of cardiac Ca2+ homeostasis in septic shock

    • Principal Investigator
      Watanabe Yasuhide
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      University of Shizuoka
      Hamamatsu University School of Medicine
  •  Drug discovery platform for improvement of positive inotropic effect in septic myocardium

    • Principal Investigator
      Matsuda Naoyuki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Nagoya University
  •  Studies on GRK2 as a potential drug discovery target for the sepsis syndromePrincipal Investigator

    • Principal Investigator
      Hattori Yuichi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      University of Toyama
  •  Regulation of NADPH oxidase gene: the role and meaning as a therapeutic target in septic encephalopathy.

    • Principal Investigator
      YOKOO Hiroki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Tokoha University
      University of Toyama
  •  Potential therapeutic application of epigenetic mechanisms involved in the septic pathologyPrincipal Investigator

    • Principal Investigator
      HATTORI Yuichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      University of Toyama
  •  Clarifying the regulatory mechanism of insulin signal in septicemia

    • Principal Investigator
      YOKOO Hiroki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      University of Toyama
  •  Elucidation of the source of pluripotent progenitor cells in systemic inflammatory mouse model

    • Principal Investigator
      YAMAMOTO Seiji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      University of Toyama
  •  The transcription factor AP-1 as a molecular target in sepsis therapyPrincipal Investigator

    • Principal Investigator
      HATTORI Yuichi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      University of Toyama
  •  Potential usefulness of siRNAs for gene therapy ofsepsis-induced multiple organ failurePrincipal Investigator

    • Principal Investigator
      HATTORI Yuichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      University of Toyama
  •  NF-κBデコイ吸入療法による敗血症ARDSの改善効果に関する基礎的研究Principal Investigator

    • Principal Investigator
      服部 裕一
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hokkaido University
  •  Cardiac dysfunction following brain death

    • Principal Investigator
      HAYASHI Yukio
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Osaka University
  •  脳毛細血管構築制御に関わるエストロゲン受容体サブタイプの遺伝子改変動物による解明Principal Investigator

    • Principal Investigator
      服部 裕一
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Hokkaido University
  •  Structure and function of receptor-operated Ca^<2+> channels and development of specific blockers of the channels

    • Principal Investigator
      MIWA Soichi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Altered expression of toll-like receptors in major organs during sepsis

    • Principal Investigator
      MATSUDA Naoyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hokkaido University
  •  エストロゲンによる心臓および脳毛細血管網構築の制御とその生理的役割に関する研究

    • Principal Investigator
      佐久間 一郎
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Hokkaido University
  •  内皮由来過分極因子の分離・同定・機能解析

    • Principal Investigator
      MIWA Soichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Hokkaido University
  •  The structure and function of voltage-independent Ca^<2+> channels involved in vascular contractions

    • Principal Investigator
      MIWA Soichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Hokkaido University
  •  Evaluation of Gs protein regulation in septic heart of gene deficiency mice

    • Principal Investigator
      GANDO Satoshi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hokkaido University
  •  Molecular mechanisms of irradiation-induced impairment eNOS expressionPrincipal Investigator

    • Principal Investigator
      HATTORI Yuichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Hokkaido University
  •  An analysis of the mechanismes of the impairment of cardiac be-ta-adrenoceptor signal transduction pathway in septic shock.

    • Principal Investigator
      GANDO Satoshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Cellular and molecular pharmacological studies on disturbance of CaィイD12+ィエD1 regulatory mechanisms in cardiomyocytes in diabetesPrincipal Investigator

    • Principal Investigator
      HATTORI Yuichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Abnormal intracellular CaィイD12+ィエD1 handling in heart failure ; effects of ACE inhibitor

    • Principal Investigator
      TOMITA Fumishi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Cellular and molecular pharmacological studies on a role of tyrosine kinase in the signal transduction system in cardiac cells.Principal Investigator

    • Principal Investigator
      HATTORI Yuichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Hokkaido University
  •  Studies on the role of protein kinase C in cardiac contractilityPrincipal Investigator

    • Principal Investigator
      HATTORI Yuichi
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Hokkaido University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] In : Targets in Gene Therapy. ed.by Yongping You.(Protection from lethal cell death in cecal ligation and puncture-induced sepsis mouse model by in vivo delivery of FADD siRNA.)2011

    • Author(s)
      Hattori Y, Matsuda N
    • Publisher
      InTec Open Access Publisher(in press)
    • Data Source
      KAKENHI-PROJECT-20590250
  • [Book] Protection from lethal cell death in cecal ligation and puncture-induced sepsis mouse model by in vivo delivery of FADD siRNA. In : Targets in Gene Therapy(ed. by Yongping You)2011

    • Author(s)
      Hattori Y, Matsuda N
    • Publisher
      InTech-Open Access Publisher
    • Data Source
      KAKENHI-PROJECT-23590298
  • [Journal Article] Vascular endotheliitis associated with infections: Its pathogenetic role and therapeutic implication.2022

    • Author(s)
      Hattori Y, Hattori K, Machida T, Matsuda N.
    • Journal Title

      Biochem Pharmacol

      Volume: 197 Pages: 114909-114909

    • DOI

      10.1016/j.bcp.2022.114909

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03757
  • [Journal Article] Vascular endothelial growth factor contributes to lung vascular hyperpermeability in sepsis-associated acute lung injury2021

    • Author(s)
      Tomita K, Saito Y, Suzuki T, Imbaby S, Hattori K, Matsuda N, Hattori Y
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol

      Volume: 393 Issue: 12 Pages: 2365-2374

    • DOI

      10.1007/s00210-020-01947-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03757
  • [Journal Article] Impact of a long-term high-glucose environment on pro-inflammatory responses in macrophages stimulated with lipopolysaccharide.2021

    • Author(s)
      Suzuki T, Yamashita S, Hattori K, Matsuda N, Hattori Y.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol

      Volume: 394 Issue: 10 Pages: 2129-2139

    • DOI

      10.1007/s00210-021-02137-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03757
  • [Journal Article] Beneficial effect of STAT3 decoy oligodeoxynucleotide transfection on organ injury and mortality in mice with cecal ligation and puncture-induced sepsis.2021

    • Author(s)
      Imbaby S, Matsuda N, Tomita K, Hattori K, Palikhe S, Yokoo H, Hattori Y.
    • Journal Title

      Sci Rep

      Volume: 10 Issue: 1 Pages: 15316-15316

    • DOI

      10.1038/s41598-020-72136-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03757
  • [Journal Article] Editorial: G protein-coupled receptor kinases (GRKs) and β-arrestins: New insights into disease regulators2020

    • Author(s)
      Yuichi Hattori, Martin C. Michel
    • Journal Title

      Forontiers in Pharmacology

      Volume: 10 Pages: 1654-1654

    • DOI

      10.3389/fphar.2019.01654

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08586
  • [Journal Article] 敗血症病態における血管内皮細胞の活性化と機能障害2019

    • Author(s)
      服部裕一、服部貢士、松田直之
    • Journal Title

      血管

      Volume: 42 Pages: 9-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08586
  • [Journal Article] Regulatory Role of GRK2 in the TLR Signaling-Mediated iNOS Induction Pathway in Microglial Cells.2019

    • Author(s)
      Palikhe S, Ohashi W, Sakamoto T, Hattori K, Kawakami M, Andoh T, Yamazaki H, Hattori Y.
    • Journal Title

      Front Pharmacol.

      Volume: - Pages: 59-59

    • DOI

      10.3389/fphar.2019.00059

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Journal Article] Nucleic-acid based gene therapy approaches for sepsis2018

    • Author(s)
      Hattori Y, Hattori K, Suzuki T, Palikhe S, Matsuda N
    • Journal Title

      Eur J Pharmacol

      Volume: 833 Pages: 403-410

    • DOI

      10.1016/j.ejphar.2018.06.031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08586, KAKENHI-PROJECT-16K19015
  • [Journal Article] Anti-inflammatory properties of cilostazol: Its interruption of DNA binding activity of NF-κB from the Toll-like receptor signaling pathways2018

    • Author(s)
      Sakamoto T, Ohashi W, Tomita K, Hattori K, Matsuda N, Hattori Y
    • Journal Title

      Int Immunopharmacol

      Volume: 62 Pages: 121-131

    • DOI

      10.1016/j.intimp.2018.06.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08586
  • [Journal Article] Different involvement of the MAPK family in inflammatory regulation in human pulmonary microvascular endothelial cells stimulated with LPS and IFN-γ2018

    • Author(s)
      Suzuki T, Sakata K, Mizuno N, Palikhe S, Yamashita S, Hattori K, Matsuda N, Hattori Y
    • Journal Title

      Immunobiology

      Volume: 223 Issue: 12 Pages: 777-785

    • DOI

      10.1016/j.imbio.2018.08.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08586, KAKENHI-PROJECT-16K19015
  • [Journal Article] Cardioprotective and functional effects of levosimendan and milrinone in mice with cecal ligation and puncture-induced sepsis2018

    • Author(s)
      Yamashita S, Suzuki T, Iguchi K, Sakamoto T, Tomita K, Yokoo H, Sakai M, Misawa H, Hattori K, Nagata T, Watanabe Y, Matsuda N, Yoshimura N, Hattori Y
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol

      Volume: 391 Issue: 9 Pages: 1021-1032

    • DOI

      10.1007/s00210-018-1527-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08586, KAKENHI-PROJECT-17K11047, KAKENHI-PROJECT-16K19015, KAKENHI-PROJECT-18H02808
  • [Journal Article] SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex2017

    • Author(s)
      Ohashi W, Yamamine N, Imura J, Hattori Y.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 493 Issue: 3 Pages: 1342-1348

    • DOI

      10.1016/j.bbrc.2017.09.161

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Journal Article] Recent advances in the pathophysiology and molecular basis of sepsis-associated organ dysfunction: Novel therapeutic implications and challenges2017

    • Author(s)
      Yuichi Hattori, Kohshi Hattori, Tokiko Suzuki, Naoyuki Matsuda
    • Journal Title

      Pharmacology & Therapeutics

      Volume: 177 Pages: 56-66

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08586
  • [Journal Article] Diminished responsiveness to dobutamine as an inotrope in mice with cecal ligation and puncture-induced sepsis: Attribution to phosphodiesterase 4 upregulation.2017

    • Author(s)
      Mari Sakai, Tokiko Suzuki, Kengo Tomita, Shigeyuki Yamashita, Sailesh Palikhe, Kohshi Hattori, Naoki Yoshimura, Naoyuki Matsuda, Yuichi Hattori
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 印刷中 Issue: 6 Pages: H1224-H1237

    • DOI

      10.1152/ajpheart.00828.2016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460336, KAKENHI-PROJECT-16K19015
  • [Journal Article] Diminished Responsiveness to Dobutamine as an Inotrope in Mice with Cecal Ligation and Puncture-Induced Sepsis: Attribution to Phosphodiesterase 4 Upregulation.2017

    • Author(s)
      Sakai M, Suzuki T, Tomita K, Yamashita S, Palikhe S, Hattori K, Yoshimura N, Matsuda N, Hattori Y.
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15661
  • [Journal Article] Gタンパク質共役型受容体キナーゼ2 (GRK2)の分子病理的役割2016

    • Author(s)
      服部裕一,服部貢士,鈴木登紀子
    • Journal Title

      日本臨床

      Volume: 74 Pages: 1761-1768

    • Data Source
      KAKENHI-PROJECT-26460336
  • [Journal Article] GRK2 as a potential therapeutic target for septic ARDS2015

    • Author(s)
      大橋若奈,服部裕一
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 145 Issue: 3 Pages: 122-128

    • DOI

      10.1254/fpj.145.122

    • NAID

      130004827732

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-26460336
  • [Journal Article] Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages.2015

    • Author(s)
      Qiang Wang, Hiroki Yokoo, Michinori Takashina, Kimimasa Sakata, Wakana Ohashi, Lobna A Abdelzaher, Takahiro Imaizumi, Takuya Sakamoto, Kohshi Hattori, Naoyuki Matsuda, Yuichi Hattori
    • Journal Title

      Critical Care Medicine

      Volume: 43巻,11号 Issue: 11 Pages: e508-e520

    • DOI

      10.1097/ccm.0000000000001269

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460336, KAKENHI-PROJECT-15K15661, KAKENHI-PROJECT-25293365
  • [Journal Article] Roles of ROS and PKC-betaII in ionizing radiation-induced eNOS activation in human vascular endothelial cells.2015

    • Author(s)
      Sakata K, Kondo T, Mizuno N, Shoji M, Yasui H, Yamamori T, Inanami O, Yokoo H, Yoshimura N, Hattori Y.
    • Journal Title

      Vascular Pharmacology

      Volume: - Pages: 55-65

    • DOI

      10.1016/j.vph.2015.03.016

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590315, KAKENHI-PROJECT-25861045, KAKENHI-PROJECT-15K09983, KAKENHI-PROJECT-26461875, KAKENHI-PROJECT-15H04904
  • [Journal Article] Control of macrophage dynamics as a potential therapeutic approach for clinical disorders involving chronic inflammation.2015

    • Author(s)
      Wakana Ohashi, Kohshi Hattori, Yuichi Hattori
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 354巻,3号 Issue: 3 Pages: 240-250

    • DOI

      10.1124/jpet.115.225540

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460336, KAKENHI-PROJECT-15K19319
  • [Journal Article] Inhibition of histone deacetylases protects septic mice from lung and splenic apoptosis.2014

    • Author(s)
      Takebe M, Oishi H, Taguchi K, Aoki Y, Takashina M, Tomita K, Yokoo H, Takano Y, Yamazaki M, Hattori Y.
    • Journal Title

      J Surg Res.

      Volume: 187 Issue: 2 Pages: 559-70

    • DOI

      10.1016/j.jss.2013.10.050

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590298, KAKENHI-PROJECT-24590315, KAKENHI-PROJECT-24791586, KAKENHI-PROJECT-25870258
  • [Journal Article] Olprinone and colforsin daropate alleviate septic lung inflammation and apoptosis through CREB-independent activation of the Akt pathway2012

    • Author(s)
      Oishi H., Takano K., Tomita K., Takebe M., Yokoo H., Yamazaki M., and HattoriY.
    • Journal Title

      Am. J. Physiol. Lung Cell Mol. Physiol

      Volume: (in press) Issue: 2 Pages: L130-L140

    • DOI

      10.1152/ajplung.00363.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271, KAKENHI-PROJECT-23590298
  • [Journal Article] Successful treatment of acute lung injury with pitavastatin in septic mice : potential role of glucocorticoid receptor expression in alveolar macrophages2011

    • Author(s)
      Takano K, Yamamoto S, Tomita K, Takashina M, Yokoo H, Matsuda N, Takano Y, Hattori Y
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 336 Pages: 381-390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] High glucose-induced apoptosis in human coronary artery endothelial cells involves up-regulation of death receptors2011

    • Author(s)
      Kageyama S, Yokoo H, Tomita K, Kageyama-Yahara N, Uchimido R, Matsuda N, Yamamoto S, Hattori Y
    • Journal Title

      Cardiovasc Diabetol

      Volume: 10 Pages: 73-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Novel insights into beneficial consequences of statins in sepsis : anti-inflammatory and anti-apoptotic mechanisms2011

    • Author(s)
      Tomita K., Takano K., Yokoo H., and Hattori Y.
    • Journal Title

      Mol. Cell. Pharmacol.

      Volume: 3 Pages: 67-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Successful treatment of acute lung injury with pitavastatin in septic mice : potential role of glucocorticoid receptor expression in alveolar macrophages2011

    • Author(s)
      Takano K., Yamamoto S., Tomita K., Takashina M., Yokoo H., Matsuda N., Takano Y., and Hattori Y.
    • Journal Title

      J. Pharmacol. Exp. Ther.

      Volume: 336 Issue: 2 Pages: 381-390

    • DOI

      10.1124/jpet.110.171462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271, KAKENHI-PROJECT-23590298
  • [Journal Article] High glucose-induced apoptosis in human coronary artery endothelial cells involves up-regulation of death receptors2011

    • Author(s)
      Kageyama S., Yokoo H., Tomita K., Kageyama-Yahara N., Uchimido R., Matsuda N., Yamamoto S., and Hattori Y.
    • Journal Title

      Cardiovasc. Diabetol.

      Volume: 10 Issue: 1 Pages: 73-73

    • DOI

      10.1186/1475-2840-10-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Successful treatment of acute lung injury with pitavastatin in septic mice : potential role of glucocorticoid receptor expression in alveolar macrophages.2011

    • Author(s)
      Takano K, Yamamoto S, Tomita K, Takashina M, Yokoo H, Matsuda N, Takano Y, Hattori Y.
    • Journal Title

      The Journal of Pharmacology and Experimental Therapeautics

      Volume: 336 Pages: 381-390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo : a relationship between telomeres and nitric oxide2011

    • Author(s)
      Matsui-Hirai H, Hayashi T, Yamamoto S, Ina K, Maeda M, Kotani H, Iguchi A, Ignarro LJ, Hattori Y
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 337 Pages: 591-599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Up-regulation of histamine H4 receptors contributes to splenic apoptosis in septic mice : counteraction of the anti-apoptotic action of nuclear factor-κB.2010

    • Author(s)
      Matsuda N, Teramae H, Futatsugi M, Takano KI, Yamamoto S, Tomita K, Suzuki T, Yokoo H, Koike K, Hattori Y
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 332 Pages: 730-737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Beneficial effect of the oligomerized polyphenol oligonol on high glucose-induced changes in eNOS phosphorylation and dephosphorylation in endothelial cells2010

    • Author(s)
      Zhang XH., Yokoo H., Nishioka H., Fujii H., Matsuda N., Hayashi T., and Hattori Y.
    • Journal Title

      Br. J. Pharmacol.

      Volume: 159 Issue: 4 Pages: 928-938

    • DOI

      10.1111/j.1476-5381.2009.00594.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Beneficial effect of the oligomerized polyphenol oligonol on high glucose-induced changes in eNOS phosphorylation and dephosphorylation in endothelial cells.2010

    • Author(s)
      Zhang XH., Yokoo H., Nishioka H., Fujii H., Matsuda N., Hayashi T., Hattori Y.
    • Journal Title

      British Journal of Pharmacology. 159

      Pages: 928-938

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Up-regulation of histamine H4 receptors contributes to splenic apoptosis in septic mice : counteraction of the antiapoptotic action of nuclear factor-κB2010

    • Author(s)
      Matsuda N. Teramae H. Futatsugi M., Takano K., Yamamoto S., Tomita K., Suzuki T. Yokoo H., Koike K., and Hattori Y.
    • Journal Title

      J. Pharmacol. Exp. Ther.

      Volume: 332 Issue: 3 Pages: 730-737

    • DOI

      10.1124/jpet.109.163543

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Increased death receptor pathway of apoptotic signaling in septic mouseaorta : effect of systemic delivery of FADD siRNA.2010

    • Author(s)
      Matsuda N, Teramae H, Yamamoto S, Takano KI, Takano Y, Hattori Y
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] 神経発生期の血管発生に関与するペリサイトのリクルートメント.2010

    • Author(s)
      山本誠士, 村松昌, 東英梨月, 堂本光子, 大澤毅, 高橋宏行, 高野健一, 浦壁聡美, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
    • Journal Title

      脈管学

      Volume: 50 Pages: 197-201

    • NAID

      10026911965

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Insights into sepsis therapeutic design based on the apoptotic death pathway.2010

    • Author(s)
      Hattori Y, Takano K, Teramae H, Yamamoto S, Yokoo H, Matsuda N.
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 114 Pages: 354-365

    • NAID

      10029890689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Insights into sepsis therapeutic design based on the apoptotic death pathway.2010

    • Author(s)
      服部裕一, 高野健一, 寺前洋生, 山本誠士, 横尾宏毅, 松田直之
    • Journal Title

      J Pharmacol Sci 114

      Pages: 354-365

    • NAID

      10029890689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590250
  • [Journal Article] Up-regulation of histamine H4 receptors contributes to splenic apoptosis in septic mice : counteraction of the antiapoptotic action of nuclear factor-kappaB2010

    • Author(s)
      Matsuda N, Teramae H, Futatsugi M, Takano K, Yamamoto S, Tomita K, Suzuki T, Yokoo H, Koike K, Hattori Y
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 332 Pages: 730-737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Insights Into Sepsis Therapeutic Design Based on the Apoptotic Death Pathway2010

    • Author(s)
      Hattori Y., Takano K., Teramae H., Yamamoto S., Yokoo H., and Matsuda N.
    • Journal Title

      J Pharmacol Sci

      Volume: 114 Issue: 4 Pages: 354-365

    • DOI

      10.1254/jphs.10R04CR

    • NAID

      10029890689

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Increased death receptor pathway of apoptotic signaling in septic mouse aorta : effect of systemic delivery of FADD siRNA.2010

    • Author(s)
      松田直之, 寺前洋生, 山本誠士, 高野健一, Takano Y, 服部裕一
    • Journal Title

      Am J Physiol Heart Circ Physiol 298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590250
  • [Journal Article] Estrogen receptor alpha and beta are both involved in the cerebral VEGF/Akt/NO pathway and cerebral angiogenesis in female mice2010

    • Author(s)
      Jesmin S., Mowa CN., Sultana SN., Mia S., Islam R., Zaedi S., Sakuma I., Hattori Y., Hiroe M., and Yamaguchi N.
    • Journal Title

      Biomed. Res.

      Volume: 31 Pages: 337-346

    • NAID

      130004470760

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Insights into sepsis therapeutic design based on the apoptotic death pathway2010

    • Author(s)
      Yuichi Hattori, et al.
    • Journal Title

      J Pharmacol Sci

      Volume: 114 Pages: 354-365

    • NAID

      10029890689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590250
  • [Journal Article] Insights into sepsis therapeutic design based on the apoptotic death pathway.2010

    • Author(s)
      Hattori Y, Takano KI, Teramae H, Yamamoto S, Yokoo H, Matsuda N
    • Journal Title

      J Pharmacol Sci

      Volume: 114 Pages: 354-365

    • NAID

      10029890689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Insights into sepsis therapeutic design based on the apoptotic death pathway2010

    • Author(s)
      Hattori Y, Takano K, Teramae H, Yamamoto S, Yokoo H, Matsuda N
    • Journal Title

      J Pharmacol Sci

      Volume: 114 Pages: 354-365

    • NAID

      10029890689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Increased death receptor pathway of apoptotic signaling in septic mouse aorta : effect of systemic delivery of FADD siRNA2010

    • Author(s)
      Matsuda N, Teramae H, Yamamoto S, Takano K, Takano Y, Hattori Y
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Up-regulation of histamine H4 receptors contributes to splenic apoptosis in septic mice : counteraction of the antiapoptotic action of nuclear factor-kappaB.2010

    • Author(s)
      M?atsuda N., Teramae H., Futatsugi M., Takano K., Yamamoto S., Tomita K., Suzuki T., Yokoo H., Koike K., Hattori Y.
    • Journal Title

      The Journal of Pharmacological and Experimental Therapeutics. 332

      Pages: 730-737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] 敗血症性ショックにおけるアポトーシスの治療2009

    • Author(s)
      松田直之, 山本誠士, 寺前洋生, 高野健一, 別府賢, 山崎弘美, 横尾宏毅, 畠山登, 小池薫, 服部裕一
    • Journal Title

      日本薬理学雑誌 134

      Pages: 198-201

    • NAID

      10025741693

    • Data Source
      KAKENHI-PROJECT-20590250
  • [Journal Article] Silencing of Fas-associated death domain protects mice from septic lung inflammation and apoptosis.2009

    • Author(s)
      Matsuda N, Yamamoto S, Takano K, Kageyama S, Kurobe Y, Yoshihara Y, Takano Y, Hattori Y
    • Journal Title

      Am J Crit Care Med 179

      Pages: 806-815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590250
  • [Journal Article] Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis2009

    • Author(s)
      Matsuda N, Yamamoto S, Yokoo H, Tobe K, Hattori Y
    • Journal Title

      Crit Care Med

      Volume: 37 Pages: 2791-2799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis2009

    • Author(s)
      Matsuda N., Yamamoto S., Yokoo H., Tobe K., and Hattori Y.
    • Journal Title

      Crit. Care Med

      Volume: 37 Issue: 10 Pages: 2791-2799

    • DOI

      10.1097/ccm.0b013e3181ab844d

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Silencing of fas-associated death domain protects mice from septic lung inflammation and apoptosis2009

    • Author(s)
      Matsuda N, Yamamoto S, Takano K, Kageyama S, Kurobe Y, Yoshihara Y, Takano Y, Hattori Y
    • Journal Title

      Am J Respir Crit Care Med

      Volume: 179 Pages: 806-815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] RNA interference targeting FADD protects mice from septic lung inflammation and apoptosis2009

    • Author(s)
      Matsuda N, Yamamoto S, Takano K, Kageyama S, Kurobe Y, Yoshiwara Y, Takano Y, Hattori Y
    • Journal Title

      Am J Respir Crit Care Med 179

      Pages: 806-815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] 敗血症性ショックにおけるアポトーシスの治療2009

    • Author(s)
      松田直之, 山本誠士, 寺前洋生, 高野健一, 別府賢, 山崎弘美, 横尾宏毅, 畠山登, 小池薫, 服部裕一
    • Journal Title

      日本薬理学会誌 134

      Pages: 198-201

    • NAID

      10025741693

    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose to lerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis.2009

    • Author(s)
      Matsuda N, Yamamoto S, Yokoo H, Tobe K, Hattori Y
    • Journal Title

      Crit Care Med 37

      Pages: 2791-2799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Journal Article] Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis.2009

    • Author(s)
      Matsuda N., Yamamoto S., Yokoo H., Tobe K., Hattori Y.
    • Journal Title

      Critical Care Medicine. 37

      Pages: 2791-2799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Journal Article] Vascular biology in sepsis: pathopysiological and therapeutic significance of vascular dysfunction2007

    • Author(s)
      Matsuda, N, Hattori, Y
    • Journal Title

      Journal of Smooth Muscle Research 43

      Pages: 117-137

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Journal Article] Vascular biology in sepsis: pathophysiological and therapeutic significance of vascular dysfunction2007

    • Author(s)
      Matsuda N, Hattori Y
    • Journal Title

      Journal of Smooth Muscle Research 43

      Pages: 117-137

    • NAID

      110006404993

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Journal Article] Vascular biology in sepsis: pathophysiological and therapeutic signficance of vascular dysfuntion2007

    • Author(s)
      Matsuda N, Hattori Y
    • Journal Title

      Journal of Smooth Muscle Research 43

      Pages: 117-137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Journal Article] Silencing of caspase-8 and caspase-3 by RNA interference prevents vascular endothelial cell injury in mice with endotoxic shock2007

    • Author(s)
      Matsuda, N, Takano, Y, Kageyama, S, Hatakeyama, N, Shakunaga, K, Kitajima, I, Yamazaki, M, Hattori, Y
    • Journal Title

      Cardiovascular Research 76

      Pages: 132-140

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Journal Article] Silencing of caspase-8 and caspase-3 by RNA interference prevents vascular endothelial cell injury in mice with endotoxic shock2007

    • Author(s)
      Matsuda N, Hattori Y, 他
    • Journal Title

      Cardiovascular Research 76

      Pages: 132-140

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Journal Article] Nuclear factor-κB decoy oligodeoxynucleotides prevent acute lung injury in mice with cecal ligation and puncture-induced sepsis.2005

    • Author(s)
      Matsuda N, Hattori Y, et al.
    • Journal Title

      Mol.Pharmacol. 67・4(in press)

    • Data Source
      KAKENHI-PROJECT-16659417
  • [Journal Article] Nuclear Factor-kB decoy oligonucleotides prevent acute lung injury in mice with cecal ligation and puncture-induced sepsis.2005

    • Author(s)
      Matsuda N, Hattori Y, Takahashi Y, Subrina Jesmin, Gando S.
    • Journal Title

      Mol Pharmacal 67

      Pages: 1018-1025

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591614
  • [Journal Article] Therapeutic effect of in vivo transfection of transcription factor decoy to NF-κB on septic lung in mice.2004

    • Author(s)
      Matsuda N, Hattori Y, et al.
    • Journal Title

      Am.J.Physiol.Lung Cell Mol.Physiol. 287・6

    • Data Source
      KAKENHI-PROJECT-16659417
  • [Journal Article] Therapeutic effect of in vivo transfection of transcription factor decoy to NF-kB on septic lung in mice2004

    • Author(s)
      Matsuda N, Hattori Y, Takahashi Y, Nishihira J, Jesmin S, Kobayashi M, Gando S.
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol 287

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591614
  • [Journal Article] Silencing of caspase-8 and caspase-3 by RNA interference prevents vascular endothelial cell injury in septic mice

    • Author(s)
      Matsuda N, Hattori Y 他
    • Journal Title

      Cardiovascular Research (in press)

    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Alert Cell Strategy:敗血症/敗血症性ショックにおけるトランスクリプトーム制御2022

    • Author(s)
      松田直之、服部裕一
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-23K24432
  • [Presentation] 敗血症性急性肺傷害の病態メカニズムと新たな治療戦略2020

    • Author(s)
      服部裕一
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K08586
  • [Presentation] STAT3 decoy oligodeoxynucleotides improve end-organ tissue injury and survival in septic mice2020

    • Author(s)
      Naoyuki Matsuda, Samar Imbaby, Kohshi Hattori, Yuichi Hattori
    • Organizer
      Experimental Biology 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08586
  • [Presentation] 亜鉛トランスポーターZIP7ががん細胞性へ及ぼす影響についての検討2019

    • Author(s)
      洞口龍介、大橋若奈、山峯直樹、服部裕一
    • Organizer
      第18回日本亜鉛栄養治療研究会
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Presentation] Zinc transporter ZIP7 regulates tumorigenic potential in human colorectal cancer cells2019

    • Author(s)
      Wakana Ohashi, Ryusuke Horaguchi, and Yuichi Hattori
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Presentation] 盲腸結紮穿刺誘発性敗血症マウスモデルにおける播種性血管内凝固症候群(DIC)2019

    • Author(s)
      坂本卓弥,Samar Imbaby,冨田賢吾、服部裕一
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K08586
  • [Presentation] がん細胞における亜鉛トランスポーターZIP7の役割の解析2019

    • Author(s)
      洞口龍介、大橋若奈、山峯直樹、服部裕一
    • Organizer
      日本生化学会第37回北陸支部会
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Presentation] Contribution of Zinc transporter in the tumorigenic potentials of human colorectal cancer cells2019

    • Author(s)
      Wakana Ohashi, Ryusuke Horaguchi, Naoki Yamamine, and Yuichi Hattori
    • Organizer
      International Society of Zinc Biology 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Presentation] 敗血症モデルマウスにおける各種デコイ核酸を用いた遺伝子治療2019

    • Author(s)
      冨田賢吾,服部裕一
    • Organizer
      第92回日本薬理学会年会(シンポジウム:感染・炎症システムを対象とした定量生命科学研究の最前線と創薬への新展開)
    • Data Source
      KAKENHI-PROJECT-17K08586
  • [Presentation] Zinc transporter SLC39A7/ZIP7 contributes to the tumorigenic potentials of human colorectal cancer cells2018

    • Author(s)
      Ryusuke Horaguchi, Wakana Ohashi, Naoki Yamamine, Tetsuro Oda, and Yuichi Hattori
    • Organizer
      18th World Congress of Basic ad Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Presentation] 大腸がんにおけるWntアゴニストSKL2001の増殖制御機構の解析2018

    • Author(s)
      大橋若奈、山峯直樹、井村穣二、服部裕一
    • Organizer
      第90回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Presentation] 敗血症性心筋症の病態形成機構の解明と新たな治療への応用.2017

    • Author(s)
      酒井麻里,芳村直樹,服部裕一
    • Organizer
      第90回日本薬理学会年会(シンポジウム:革新的心不全治療戦略創出を指向した心機能制御機構の新たな展開)
    • Place of Presentation
      長崎(長崎新聞文化ホール)
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-26460336
  • [Presentation] 亜鉛トランスポーター ZIP7 による腸管上皮恒常性維持機構2017

    • Author(s)
      大橋 若奈、長谷 耕二、深田 俊幸、服部 裕一
    • Organizer
      第68回日本薬理学会北部会
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Presentation] Role of GPCR regulatory molecules in endothelial cell inflammatory responses to high glucose.2017

    • Author(s)
      服部裕一
    • Organizer
      第81回日本循環器学会学術集会(Topic 3:Endothelium, Health and Diseases)
    • Place of Presentation
      金沢(金沢都ホテル)
    • Year and Date
      2017-03-18
    • Data Source
      KAKENHI-PROJECT-26460336
  • [Presentation] 亜鉛トランスポーターZIP7の大腸がんにおける機能解析2017

    • Author(s)
      山峯 直樹、大橋 若奈、織田 哲郎、洞口 龍介、服部 裕一
    • Organizer
      2017年度 生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Presentation] Histamine as a potential mediator that actively promotes the development of organ injury in sepsis2017

    • Author(s)
      Yuichi Hattori
    • Organizer
      1st Joint Meeting of the European Histamine Research Society and the Japanese Histamine Research Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08586
  • [Presentation] 大腸がんにおける亜鉛トランスポーター ZIP7 の役割2017

    • Author(s)
      山峯 直樹、大橋 若奈、織田 哲郎、洞口 龍介、服部 裕一
    • Organizer
      第68回日本薬理学会北部会
    • Data Source
      KAKENHI-PROJECT-17K09373
  • [Presentation] ヒト肺微小血管内皮細胞においてβ-arrestin2は炎症応答反応を制御している2015

    • Author(s)
      坂田公正,水野夏実,芳村直樹,服部裕一
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2015-03-19
    • Data Source
      KAKENHI-PROJECT-26460336
  • [Presentation] Gタンパク質共役受容体活性制御機構分子を標的とした糖尿病性心血管障害の治療戦略.2015

    • Author(s)
      服部裕一
    • Organizer
      第17回応用薬理シンポジウムシンポジウム(生活習慣病に対する治療戦略 II ―循環器疾患―)
    • Place of Presentation
      新潟(新潟大学医学部有壬記念館)
    • Year and Date
      2015-09-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460336
  • [Presentation] 強心薬レボシメンダンの敗血症マウスに対する有益な効果とその作用機構2014

    • Author(s)
      坂田公正、横尾宏毅、服部裕一、他
    • Organizer
      第24回日本循環薬理学会
    • Place of Presentation
      山形テルサ(山形市)
    • Year and Date
      2014-12-05
    • Data Source
      KAKENHI-PROJECT-24590315
  • [Presentation] Protection from both inflammation and apoptosis as a novel therapeutic strategy for severe sepsis."All about Shock"2013

    • Author(s)
      Yuichi Hattori
    • Organizer
      The 4th Critical Care Conference in Thailand 2013
    • Place of Presentation
      Pattaya
    • Year and Date
      2013-06-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590298
  • [Presentation] The oligomerized polyphenol oligonol ameliorates high glucose- and TNF-alpha-induced NADPH oxidase activation and insulin signaling downregulation in vascular endothelial cells.2013

    • Author(s)
      Yokoo H, Taguchi K, Hattori Y.
    • Organizer
      Experimental Biology 2013
    • Place of Presentation
      Boston, MA
    • Data Source
      KAKENHI-PROJECT-24590315
  • [Presentation] Possible role of epigenetic modifications in the pathology of sepsis2013

    • Author(s)
      Mariko Takebe, Hirofumi Oishi, Yuta Aoki, Yuichi Hattori, Mitsuaki Yamazaki
    • Organizer
      Euroanaesthesia 2013
    • Place of Presentation
      Barcelona
    • Year and Date
      2013-06-02
    • Data Source
      KAKENHI-PROJECT-23590298
  • [Presentation] 敗血症の病理学的変化におけるエピジェネティックス制御の関与2013

    • Author(s)
      武部真理子, 大石博史, 青木優太, 高階道徳, 冨田賢吾, 田口久美子, 横尾宏毅, 山崎光章, 服部裕一
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2013-03-23
    • Data Source
      KAKENHI-PROJECT-23590298
  • [Presentation] Possible role of epigenetic modifications in the pathology of sepsis.2013

    • Author(s)
      Takebe M,Oishi H,Aoki Y,Hattori Y, Yamazaki M
    • Organizer
      Euroanaesthesia 2013
    • Place of Presentation
      Barcelona, Spain.
    • Data Source
      KAKENHI-PROJECT-23590298
  • [Presentation] レスベラトロールは敗血症マウス肺組織においてSIRT-1を賦活化し肺炎症・アポトーシスを緩和する2012

    • Author(s)
      高階道徳,冨田賢吾,横尾宏毅,服部裕一
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] レスベラトロールは敗血症マウス肺組織においてSIRT1を賦活化し肺炎症・アポトーシスを緩和する2012

    • Author(s)
      高階道徳, 冨田賢吾, 横尾宏毅, 服部裕一
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 新規HDAC阻害薬CG200745は敗血症アポトーシスを阻止する2012

    • Author(s)
      武部真理子, 大石博史, 青木優太, 高階道徳, 冨田賢吾, 田口久美子, 横尾宏毅, 山崎光章, 服部裕一
    • Organizer
      第63回日本薬理学会北部会
    • Place of Presentation
      新潟
    • Year and Date
      2012-09-14
    • Data Source
      KAKENHI-PROJECT-23590298
  • [Presentation] 敗血症マウス脳組織におけるNADPHオキシダーゼ活性増加と組織病理学的変化との関係2012

    • Author(s)
      横尾宏毅, 山本誠士, 服部裕一
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] エンドトキシン局所投与による急性肺炎症に対するNF-κBおとり核酸経華投与の効果2012

    • Author(s)
      冨田賢吾, 高野健一, 高階道徳, 横尾宏毅, 服部裕一
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] エンドトキシン局所投与による急性肺炎症に対するNF-κBおとり核酸経鼻投与の効果2012

    • Author(s)
      冨田賢吾,高野健一,高階道徳,横尾宏毅,服部裕一
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 敗血症マウス脳組織におけるNADPHオキシダーゼ活性増加と組織病理学的変化との関係2012

    • Author(s)
      横尾宏毅,山本誠士,服部裕一
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] II型糖尿病マウスにおける冠血管内皮にみられたDeath受容体の発現2011

    • Author(s)
      横尾宏毅, 山本誠士, 冨田賢吾, 影山俊一郎, 服部裕一
    • Organizer
      第62回日本薬理学会北部会
    • Place of Presentation
      江陽グランドホテル(仙台市)
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] EMPs behave as the bioactive carrier in inflammatory condition2011

    • Author(s)
      Yamamoto S, Azuma E, Muramatsu M, Yanagibashi T, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Dohmoto M, Matsuda N, Niida S, Hattori Y
    • Organizer
      The Second Pacific Symposium on Vascular Biology
    • Place of Presentation
      Jeju, Korea
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Histopathological changes in septic mouse brain : effect of the free-radical scavenger edaravone2011

    • Author(s)
      Yokoo H, Hattori Y
    • Organizer
      Experimental Biology 2011
    • Place of Presentation
      Walter E.Washington Convention Center (Washington DC)
    • Year and Date
      2011-04-12
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 脳血管内皮細胞由来EMPのin vitro産生系の確立と疾患biomarkerおよびbioactive carrierとしての検討2011

    • Author(s)
      山本誠士, 東英梨月, 村松昌, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 宮崎賢治, 堂本光子, 新飯田俊平, 服部裕一
    • Organizer
      第52回日本脈管学会総会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-10-21
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 敗血症マウスでの肺炎症およびアポトーシスに対するNF-κBデコイ核酸気管内投与の効果2011

    • Author(s)
      冨田賢吾, 高野健一, 高階道徳, 山本誠士, 横尾宏毅, 服部裕一
    • Organizer
      第62回日本薬理学会北部会
    • Place of Presentation
      江陽グランドホテル(仙台市)
    • Year and Date
      2011-09-29
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] Endothelial microparticles (EMP)の生物活性の解析2011

    • Author(s)
      山本誠士, 東英梨月, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 宮崎賢治, 堂本光子, 村松昌, 新飯田俊平, 服部裕一
    • Organizer
      第21回日本循環薬理学会
    • Place of Presentation
      岡山
    • Year and Date
      2011-12-02
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 敗血症マウス脳におけるニトロ化ストレス増加と神経細胞変性2011

    • Author(s)
      横尾宏毅, 山本誠士, 千葉政一, 相良洋, 冨田賢吾, 高野健一, 高階道徳, 松田直之, 服部裕一
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      日本薬理学会誌上
    • Year and Date
      2011-03-24
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] EMPのbioactive carrierという側面からの解析2011

    • Author(s)
      山本誠士, 東英梨月, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 宮崎賢治, 堂本光子, 村松昌, 新飯田俊平, 服部裕一
    • Organizer
      第62回日本薬理学会北部会
    • Place of Presentation
      仙台
    • Year and Date
      2011-09-29
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Endothelial microparticlesの疾患バイオマーカーとしての可能性の検討2011

    • Author(s)
      山本誠士, 東英梨月, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 宮崎賢治, 堂本光子, 村松昌, 新飯田俊平, 服部裕一
    • Organizer
      第32回日本循環制御学会総会
    • Place of Presentation
      富山
    • Year and Date
      2011-06-10
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 敗血症マウス脳におけるニトロ化ストレス増加と神経細胞変性2011

    • Author(s)
      横尾宏毅,山本誠士,千葉政一,相良洋,冨田賢吾,高野健一,高階道徳,松田直之,服部裕一
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      誌上
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] II型糖尿病マウスにおける冠血管内皮にみられたDeath受容体の発現2011

    • Author(s)
      横尾宏毅,山本誠士,冨田賢吾,影山俊一郎,服部裕一
    • Organizer
      第62回日本薬理学会北部会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 敗血症マウスでの肺炎症およびアポトーシスに対するNF-κBデコイ核酸気管内投与の効果2011

    • Author(s)
      冨田賢吾,高野健一,高階道徳,山本誠士,横尾宏毅,服部裕一
    • Organizer
      第62回日本薬理学会北部会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] Analysis of the multifunctional macrophages in mouse angiogenesis model2011

    • Author(s)
      Azuma E, Yamamoto S. Hattori Y, Muramatsu M, Niida S
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Endothelial microparticles (EMP)のin vitro産生系の確立と炎症biomarkerおよびbioactive carrierとしての検討2011

    • Author(s)
      山本誠士, 東英梨月, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 宮崎賢治, 堂本光子, 村松昌, 新飯田俊平, 服部裕一
    • Organizer
      第53回日本平滑筋学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-03
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Histopathological changes in septic mouse brain : effect of the free-radical scavenger edaravone2011

    • Author(s)
      Yokoo H., and Hattori Y.
    • Organizer
      Experimental Biology 2011
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] マウス敗血症性急性肺傷害におけるolprinoneとcolforsinの治療効果にはAkt活性が関与する2011

    • Author(s)
      大石博史,高野健一,冨田賢吾,武部真理子,横尾宏毅,山崎光章,服部裕一
    • Organizer
      第62回日本薬理学会北部会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] Elucidation of the nature of the endothelial microparticles2011

    • Author(s)
      Yamamoto S, Azuma E, Yanagibashi T, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Dohmoto M, Muramatsu M, Niida S, Hattori Y
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] クロモグリク酸ナトリウム気管内投与による敗血症マウス肺組織の炎症関連サイトカイン遺伝子に対する効果2011

    • Author(s)
      高野健一,冨田賢吾,横尾宏毅,服部裕一
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      誌上
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] マウス敗血症性急性肺傷害におけるオルプリノンの効果2011

    • Author(s)
      大石博史, 高野健一, 横尾宏毅, 武部真理子, 服部裕一, 山崎光章
    • Organizer
      日本麻酔科学会第58回学術集会
    • Place of Presentation
      神戸ポートピアホテル(神戸市)
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] マウス敗血症性急性肺傷害におけるolprinoneとcolforsinの治療効果にはAkt活性が関与する2011

    • Author(s)
      大石博史, 高野健一, 冨田賢吾, 武部真理子, 横尾宏毅, 山崎光章, 服部裕一
    • Organizer
      第62回日本薬理学会北部会
    • Place of Presentation
      江陽グランドホテル(仙台市)
    • Year and Date
      2011-09-29
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 敗血症アポトーシスに対する薬理学的展望2011

    • Author(s)
      服部裕一
    • Organizer
      シンポジウムテーマ:敗血症における全身炎症と細胞死座長:松田直之, 松本義也第21回日本Cell Death学会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-07-27
    • Data Source
      KAKENHI-PROJECT-23590298
  • [Presentation] マウス敗血症性急性肺傷害におけるオルプリノンの効果2011

    • Author(s)
      大石博史,高野健一,横尾宏毅,武部真理子,服部裕一,山崎光章
    • Organizer
      日本麻酔科学会第58回学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 神経発生期における脳微小血管網を被覆するペリサイトの起源2011

    • Author(s)
      山本誠士, 村松昌, 東英梨月, 堂本光子, 高野健一, 喜多紗斗美, 岩本隆宏, 小室一成, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-23
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] アポトーシスからの保護と関連した敗血症性急性肺傷害の治療.シンポジウムS1C13:急性肺傷害におけるトランスレーショナルリサーチの現状と展望(オーガナイザー:服部裕一,松田直之)2011

    • Author(s)
      高野健一, 大石博史, 服部裕一
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜(震災のため誌上発表)
    • Data Source
      KAKENHI-PROJECT-20590250
  • [Presentation] Endothelial microparticles behave as a bioactive carrier in the cellular interaction2011

    • Author(s)
      Yamamoto S, Azuma E, Yanagibashi T, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Dohmoto M, Muramatsu M, Niida S, Hattori Y
    • Organizer
      The 19th Annual Meeting of the Japanese Vascular Biology and Medicine Organization/The 1st Asia-Pacific Vascular Biology Meeting
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 臨床診断に使用される敗血症バイオマーカーの盲腸結紮穿孔誘発性敗血症マウスでの血中濃度の変化2011

    • Author(s)
      冨田賢吾,高野健一,高階道徳,横尾宏毅,服部裕一
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      誌上
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] EMPs behave as the bioactive carrier in inflammatory condition. The Second Pacific Symposium on Vascular Biology2011

    • Author(s)
      Yamamoto S, Azuma E, Muramatsu M, Yanagibashi T, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Dohmoto M, Matsuda N, Niida S, Hattori Y
    • Organizer
      The Second Pacific Symposium on Vascular Biology
    • Place of Presentation
      Jeju, Korea
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] クロモグリク酸ナトリウム気管内投与による敗血症マウス肺組織の炎症関連サイトカイン遺伝子に対する効果2011

    • Author(s)
      高野健一, 冨田賢吾, 横尾宏毅, 服部裕一
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      日本薬理学会誌上
    • Year and Date
      2011-03-23
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 臨床診断に使用される敗血症バイオマーカーの盲腸結紮穿孔誘発性敗血症マウスでの血中濃度の変化2011

    • Author(s)
      冨田賢吾, 高野健一, 高階道徳, 横尾宏毅, 服部裕一
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      日本薬理学会誌上
    • Year and Date
      2011-03-24
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] NG2 positive cerebral microvascular pericytes are potentially derived from circulating myeloid progenitors.2010

    • Author(s)
      Yamamoto S, Muramatsu M, Azuma E, Dohmoto M, Koo BN, Mukouyama Y, Osawa T, Takahashi H, Takano KI, Watanabe Y, Ikutani M, Nagai Y, Takatsu K, Usui I, Tobe K, Niida S, Shibuya M, Matsuda N, Hattori Y
    • Organizer
      The 16th International Vascular Biology Meeting
    • Place of Presentation
      UCLA, Los Angeles, California
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 脳微小血管ヘリクルートされるペリサイト前駆細胞の起源2010

    • Author(s)
      山本誠土, 村松昌, 東英梨月, 堂本光子, 大澤毅, 高橋宏行, 高野健一, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
    • Organizer
      第52回日本平滑筋学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2010-07-02
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] マウス脳血管内皮細胞株を用いたEndothelial microparticles(EMP)のin vitro産生系の確立および疾患バイオマーカーとしての可能性の検討2010

    • Author(s)
      山本誠士, 東英梨月, 村松昌, 宮崎賢治, 佐竹美芽, 堂本光子, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 新飯田俊平, 服部裕一
    • Organizer
      第33回日本分子生物学会(BMB2010)
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 敗血症マウスモデル脳組織における脳血液関門透過性亢進に伴う神経細胞変性2010

    • Author(s)
      横尾宏毅,山本誠士,高野健一,冨田賢吾,千葉政一,山崎弘美,高階道徳,松田直之,服部裕一
    • Organizer
      第61回日本薬理学会北部会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] Ncx1変異体マウスを用いた神経発生期におけるペリサイトリクルートメントの解析2010

    • Author(s)
      山本越圭, 村松昌, 東英梨月, 堂本光子, 喜多紗斗美, 岩本隆宏, 大澤毅, 高橋宏行, 渡邊泰秀, 小室一成, 高野健一, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Pitavastatin improves lung inflammation and survival in septic mice : prevention of reduced lung glucocorticoid receptors.2010

    • Author(s)
      Takano K., Yamamoto S., Tomita K., Yamazaki H., Yokoo H., Takano Y., Hattori Y.
    • Organizer
      WorldPharma2010 16th World Congress on Basic and Clinical Pharmacology
    • Place of Presentation
      Bella Center Copenhagen(Copenhagen, Denmark)
    • Year and Date
      2010-07-19
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] Pitavastatin improves lung inflammation and survival in septic mice : prevention of reduced lung glucocorticoid receptors.2010

    • Author(s)
      Takano KI, Yamamoto S, Tomita K, Yamazaki H, Yokoo H, Takano Y, Hattori Y
    • Organizer
      16th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] ピタバスタチンによるマウスの敗血症性肺損傷軽減にはグルココルチコイド受容体減少の阻止が関与する2010

    • Author(s)
      高野健一,山本誠士,冨田賢吾,山崎弘美,横尾宏毅,高野康雄,服部裕一
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 敗血症マウスにおける心臓及び肺でのリモデリング関連分子の遺伝子発現の検討2010

    • Author(s)
      冨田賢吾, 高野健一, 山本誠士, 横尾宏毅, 松田直之, 服部裕一
    • Organizer
      第61回日本薬理学会北部会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] Inhaled TAK1 siRNA improves lung inflammation and apoptosis by reducing transcriptional activity of NF-κB and AP-1 in septic mice2010

    • Author(s)
      Matsuda N, Hattori Y, Yamamoto S, Teramae H, Koike K
    • Organizer
      Society of Critical Care Medicine 39th Critical Care Congress
    • Place of Presentation
      Miami, Florida
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] ピタバスタチンによるマウスの敗血症性肺損傷軽減には, グルココルチコイド受容体減少の阻止が関与する2010

    • Author(s)
      高野健一, 冨田賢吾, 山本誠士, 山崎弘美, 横尾宏毅, 高野康雄, 服部裕一
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 敗血症マウスにおける心リモデリングに寄与する分子群の発現変化に対するピタバスタチンの効果2010

    • Author(s)
      冨田賢吾, 高野健一, 山本誠士, 内御堂亮, 横尾宏毅, 松田直之, 畠山登, 山崎光章, 服部裕一
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-03-18
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] Pitavastatin improves lung inflammation and survival in septic mice : prevention of reduced lungglucocorticoid receptors2010

    • Author(s)
      Takano KI, Yamamoto S, Tomita K, Yamazaki H, Yokoo H, Takano Y, Hattori Y
    • Organizer
      16th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Cerebrovascular pericytes are potentially derived from the circulating myeloid progenitors2010

    • Author(s)
      Yamamoto S, Muramatsu M, Azuma E, Dohmoto M, Osawa T, Takahashi H, Takano KI, Ikutani M, Nagai Y, Takatsu K, Usui I, Tobe K, Niida S, Shibuya M, Matsuda N, Hattori Y
    • Organizer
      Keystone Symposia, Angiogenesis in Health and Disease
    • Place of Presentation
      Keystone, Colorado
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Pitavastatin improves lung inflammation and survival in septic mice : prevention of reduced lung glucocorticoid receptors2010

    • Author(s)
      Takano K., Yamamoto S., Tomita K., Yamazaki H., Yokoo H., Takano Y., and Hattori Y.
    • Organizer
      WorldPharma 2010 16th World Congress on Basic and Clinical Pharmacology
    • Place of Presentation
      Copenhagen
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] Inhaled TAK1 siRNA improves lung inflammation and apoptosis by reducing transcriptional activity of NF-κB and AP-1 in septic mice.2010

    • Author(s)
      Matsuda N, Hattori Y, Yamamoto S, Teramae H, Koike K
    • Organizer
      Society of Critical Care Medicine 39th Critical Care Congress
    • Place of Presentation
      Miami, Florida
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Cerebrovascular pericytes are potentially derived from the circulating myeloid progenitors.2010

    • Author(s)
      Yamamoto S, Muramatsu M, Azuma E, Dohmoto M, Osawa T, Takahashi H, Takano KI, Ikutani M, Nagai Y, Takatsu K, Usui I, Tobe K, Niida S, Shibuya M, Matsuda N, Hattori Y
    • Organizer
      Keystone Symposia, Angiogenesis in Health and Disease
    • Place of Presentation
      Keystone, Colorado
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] マウス創傷治癒モデルにおける創傷面血管新生へのmacrophage系細胞の関与2010

    • Author(s)
      東英梨月, 山本誠士, 新飯田俊平, 堂本光子, 服部裕一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 血管内皮細胞株を用いたEndothelial microparticles(EMP)の効率的な産生系の確立および疾患バイオマーカーとしての可能性の検討2010

    • Author(s)
      山本誠士, 東英梨月, 村松昌, 宮崎賢治, 佐竹美芽, 堂本光子, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 新飯田俊平, 服部裕一
    • Organizer
      第20回日本循環薬理学会
    • Place of Presentation
      札幌
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 脳神経細胞におけるインスリンシグナル:恒常性維持のためのシグナル変動2010

    • Author(s)
      横尾宏毅,根本隆行,柳田俊彦,山本誠士,冨田賢吾,高野健一,服部裕一
    • Organizer
      第38回薬物活性シンポジウム,シンポジウム「中枢神経系とストレス応答」
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 脳血管内皮細胞株を用いたendothelial microparticles(EMP)のin vitro産生系の確立およびin vivo病態モデルでの解析2010

    • Author(s)
      山本誠士, 東英梨月, 村松昌, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 渡邉淳, 堂本光子, 新飯田俊平, 服部裕一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] CNS pericytes originate from the circulating hematopoietic progenitors.2010

    • Author(s)
      Yamamoto S, Muramatsu M, Azuma E, Dohmoto M, Kita S, Iwamoto T, Komuro I, Takano KI, Niida S, Shibuya M, Matsuda N, Hattori Y
    • Organizer
      16th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 脳神経細胞におけるインスリンシグナル:恒常性維持のためのシグナル変動2010

    • Author(s)
      横尾宏毅, 根本隆行, 柳田俊彦, 山本誠士, 冨田賢吾, 高野健一, 服部裕一
    • Organizer
      第38回薬物活性シンポジウムシンポジウム「中枢神経系とストレス応答」
    • Place of Presentation
      札幌市教育文化会館(札幌市)
    • Year and Date
      2010-11-02
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] マウス創傷治癒モデルにおけるmacrophage系細胞の血管新生への関与2010

    • Author(s)
      東英梨月, 山本誠士, 新飯田俊平, 堂本光子, 服部裕一
    • Organizer
      第33回日本分子生物学会(BMB2010)
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 多菌性敗血症マウスモデルにおける脳組織の形態学的解析2010

    • Author(s)
      横尾宏毅,山本誠士,千葉政一,冨田賢吾,高野健一,島田達生,松田直之,服部裕一
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 敗血症マウスにおける心臓及び肺でのリモデリング関連分子の遺伝子発現の検討2010

    • Author(s)
      冨田賢吾,高野健一,山本誠士,横尾宏毅,松田直之,服部裕一
    • Organizer
      第61回日本薬理学会北部会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 敗血症マウスモデル脳組織における脳血液関門透過性亢進に伴う神経細胞変性2010

    • Author(s)
      横尾宏毅, 山本誠士, 高野健一, 冨田賢吾, 千葉政一, 山崎弘美, 高階道徳, 松田直之, 服部裕一
    • Organizer
      第61回日本薬理学会北部会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] Endotheiial microparticles(EMP)のin vitro産生系の確立およびin vivo病態モデルでの解析2010

    • Author(s)
      山本誠士, 東英梨月, 村松昌, 宮崎賢治, 佐竹美芽, 堂本光子, 新飯田俊平, 服部裕一
    • Organizer
      第61回日本薬理学会北部会
    • Place of Presentation
      札幌
    • Year and Date
      2010-10-10
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] CNS pericytes originate from the circulating hematopoietic progenitors2010

    • Author(s)
      Yamamoto S, Muramatsu M, Azuma E, Dohmoto M, Kita S, Iwamoto T, Komuro I, Takano KI, Niida S, Shibuya M, Matsuda N, Hattori Y
    • Organizer
      16th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 敗血症マウスにおける心リモデリングに寄与する分子群の発現変化に対するピタバスタチンの効果2010

    • Author(s)
      冨田賢吾,高野健一,山本誠士,内御堂亮,横尾宏毅,松田直之,畠山登,山崎光章,服部裕一
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 多菌性敗血症マウスモデルにおける脳組織の形態学的解析2010

    • Author(s)
      横尾宏毅, 山本誠士, 千葉政一, 冨田賢吾, 高野健一, 島田達生, 松田直之, 服部裕一
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] NG2 positive cerebral microvascular pericytes are potentially derived from circulating myeloid progenitors2010

    • Author(s)
      Yamamoto S, Muramatsu M, Azuma E, Dohmoto M, Koo BN, Mukouyama Y, Osawa T, Takahashi H, Takano KI, Watanabe Y, Ikutani M, Nagai Y, Takatsu K, Usui I, Tobe K, Niida S, Shibuya M, Matsuda N, Hattori Y
    • Organizer
      The 16th International Vascular Biology Meeting
    • Place of Presentation
      UCLA, Los Angeles, California
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 多菌性敗血症マウスモデルでの心筋リモデリング関連分子の変化に対するpitavastatinの治療効果2009

    • Author(s)
      冨田賢吾, 高野健一, 山本誠士, 横尾宏毅, 松田直之, 畠山登, 山崎光章, 服部裕一
    • Organizer
      第19回日本循環薬理学会
    • Place of Presentation
      京都大学百周年時計台記念館(京都市)
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] ペリサイト前駆細胞は中枢神経発生期に脳微小血管ヘリクルートされる2009

    • Author(s)
      山本誠士, 村松昌, 大澤毅, 高橋宏行, 高野健一, 生谷尚士, 長井良憲, 高津聖志, 薄井勲, 戸邉一之, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
    • Organizer
      第51回日本平滑筋学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-07-22
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 敗血症性ショックと内皮由来および誘発性NO合成酵素:スタチンによる治療効果.シンポジウムS28:血管弛緩機構の異常に基づく疾患と薬物作用(オーガナイザー:岡本博,鎌田勝雄)2009

    • Author(s)
      服部裕一, 松田直之
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-20590250
  • [Presentation] 敗血症性ショックと内皮由来および誘発性NO合成酵素 : スタチンによる治療効果2009

    • Author(s)
      服部裕一, 松田直之
    • Organizer
      日本薬学会第129年会 シンポジウムS28 : 血管弛緩機構の異常に基づく疾患と薬物作用
    • Place of Presentation
      グランドプリンスホテル京都
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-20590250
  • [Presentation] 多菌性敗血症モデルでの心筋リモデリング関連分子の変化に対するpitavastatinの治療効果2009

    • Author(s)
      冨田賢吾,高野健一,山本誠士,横尾宏毅,松田直之,畠山登,山崎光章,服部裕一
    • Organizer
      第19回日本循環薬理学会
    • Place of Presentation
      京都
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] Involvement of Ca2+and Na+Channels in the mechanism of tachyarrhythmia in septic guinera pig atrium2009

    • Author(s)
      Hatakeyama N, Matsuda N, Yamamoto S, Aoki Y, Hattori Y, Yamazaki M
    • Organizer
      Society of critical Care Medicine 38th Critical Care Congress
    • Place of Presentation
      Nashville
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 中枢神経発生期におけるペリサイト前駆細胞の脳微小血管網へのリクルートメント2009

    • Author(s)
      山本誠士, 村松昌, 大澤毅, 高橋宏行, 東英梨月, 堂本光子, 高野健一, 生谷尚士, 長井良憲, 高津聖志, 薄井勲, 戸邉一之, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
    • Organizer
      第19回日本循環薬理学会
    • Place of Presentation
      京都
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Macrophage形成不全マウスおよびtime lapse imagingを用いたペリサイト前駆細胞の発生学的検討2009

    • Author(s)
      山本誠士, 村松昌, 大澤毅, 高橋宏行, 高野健一, 生谷尚士, 長井良憲, 高津聖志, 薄井勲, 戸邉一之, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
    • Organizer
      第17回日本血管生物医学会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Impact of transcription factor decoy to AP-1 on the Lung apoptosis of septic mice2009

    • Author(s)
      Matsuda N, Hattori Y, Yamamoto S, Yamazaki H, Koike K
    • Organizer
      Society of critical Care Medicine 38th Critical Care Congress
    • Place of Presentation
      Nashville
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 多菌性敗血症マウスモデルでの心筋リモデリング関連分子の変化に対するpitava statinの治療効果2009

    • Author(s)
      冨田賢吾, 高野健一, 山本誠士, 横尾宏毅, 松田直之, 畠山登, 山崎光章, 服部裕一
    • Organizer
      第19回日本循環薬理学会
    • Place of Presentation
      京都
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] マウス創傷治癒モデルにおける血管新生因子の解析2009

    • Author(s)
      東英梨月, 山本誠士, 堂本光子, 服部裕一
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] Myeloid系細胞形成不全マウスを用いたペリサイト前駆細胞の発生学的検討および発現遺伝子解析2009

    • Author(s)
      山本誠士?, 村松昌, 大澤毅, 高橋宏行, 高野健一, 生谷尚士, 長井良憲, 高津聖志, 薄井勲, 戸邉一之, 新飯田俊平, 澁谷正史, 松田直之、服部裕一
    • Organizer
      第60回日本薬理学会北部会
    • Place of Presentation
      富山
    • Year and Date
      2009-09-26
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] マウス敗血症性急性肺損傷におけるピタバスタチンの抗炎症作用とそのメカニズム2009

    • Author(s)
      高野健一,冨田賢吾,山本誠士,山崎弘美,横尾宏毅,高野康雄,服部裕一
    • Organizer
      第60回日本薬理学会北部会
    • Place of Presentation
      富山
    • Year and Date
      2009-09-26
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 敗血症病態におけるアポトーシスの治療.シンポジウムS1C-8:アポトーシス関連分子を標的とした疾病治療に向けて(オーガナイザー:服部裕一,田熊一敞)2009

    • Author(s)
      松田直之, 服部裕一
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-20590250
  • [Presentation] マウス敗血症性急性肺損傷におけるピタバスタチンの抗炎症作用とそのメカニズム2009

    • Author(s)
      高野健一, 冨田賢吾, 山本誠士, 山崎弘美, 横尾宏毅, 高野康雄, 服部裕一
    • Organizer
      第60回日本薬理学会北部会
    • Place of Presentation
      富山
    • Year and Date
      2009-09-26
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] マウス敗血症性急性肺損傷におけるピタバスタチンの抗炎症作用とそのメカニズム2009

    • Author(s)
      高野健一, 冨田賢吾, 山本誠士, 山崎弘美, 横尾宏毅, 高野康雄, 服部裕一
    • Organizer
      第60回日本薬理学会北部会
    • Place of Presentation
      富山国際会議場(富山市)
    • Year and Date
      2009-09-26
    • Data Source
      KAKENHI-PROJECT-21590271
  • [Presentation] 敗血症病態におけるアポトーシスの治療2009

    • Author(s)
      松田直之, 服部裕一
    • Organizer
      第82回日本薬理学会年会 シンポジウムS1C-8アポトーシス関連分子を標的とした疾病治療に向けて
    • Place of Presentation
      パシフイコ横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-20590250
  • [Presentation] 脳微小血管網を構成するペリサイトは造血系細胞由来である2009

    • Author(s)
      山本誠士, 村松昌, Bon-nyeo Koo, 向山洋介, 喜多紗斗美, 岩本隆宏, 東英梨月, 堂本光子, 渡邊泰秀, 小室一成, 大澤毅, 高橋宏行, 高野健一, 生谷尚士, 長井良憲, 高津聖志, 薄井勲, 戸邉一之, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21590589
  • [Presentation] 敗血症性ショックに対するFADD siRNAによる治療-敗血症心筋ではアポトーシスが進行する-2008

    • Author(s)
      松田 直之, 服部 裕一, ほか
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-19
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] 敗血症性ショックに対するFADD siRNAによる治療 -敗血症心筋ではアポトーシスが進行する-2008

    • Author(s)
      松田直之, 服部裕一, ほか
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Molecular pathophysiology of vascular endothelial dysfunction in systemic inflammatory response syndrome and sepsis2007

    • Author(s)
      Matsuda, N, Hattori, Y
    • Organizer
      The 80th Annual Meeting of the Japanese Pharmacological Society(Symposium S2A1)
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-03-15
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Reversal effects of FADD siRNA on apoptosis-associated cardiac dysfunction in septic mice2007

    • Author(s)
      Matsuda, N, Hattori, Y,, et. al.
    • Organizer
      The 81st Annual Meeting of the Japanese Pharmacological Society
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-03-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] FADD siRNAによる敗血症血管傷害の遺伝子治療2007

    • Author(s)
      松田直之, 服部裕一
    • Organizer
      第36回日本心脈管作動物質学会
    • Place of Presentation
      徳島
    • Year and Date
      2007-02-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Potential usefulness of FADD siRNAfor gene therapy of septic vascular injury2007

    • Author(s)
      Matsuda, N, Hattori, Y
    • Organizer
      The 36th Annual Meeting of the Japanese Circulation Research
    • Place of Presentation
      Tokushima
    • Year and Date
      2007-02-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] 敗血症性ショックにおける血管内皮細胞機能異常の意義(シンポジウム:生活習慣病から急性疾患に至るまでの血管内皮細胞障害の重要性)2007

    • Author(s)
      松田直之, 服部裕一
    • Organizer
      第80回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-03-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Regulation of the histamine signaling pathway by inducible transcription factors: A novel mechanism for the anti-allergic actions of DSCG2007

    • Author(s)
      Hattori, Y, Matsuda, N
    • Organizer
      The 127thAnnual Meeting of the Pharmaceutical Society of Japan(Symposium S22)
    • Place of Presentation
      Toyama
    • Year and Date
      2007-03-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] 敗血症性急性肺傷害のFADD siRNAによる遺伝子治療2007

    • Author(s)
      松田直之, 服部裕一, ほか
    • Organizer
      第58回日本薬理学会北部会
    • Place of Presentation
      札幌
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] 敗血症主臓器におけるヒスタミンH4受容体の役割(シンポジウム:H4受容体の調節機構と病態生理学的役割)2007

    • Author(s)
      松田直之, 服部裕一
    • Organizer
      第11回日本ヒスタミン学会
    • Place of Presentation
      富山
    • Year and Date
      2007-12-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] 誘発性転写因子によるヒスタミンシグナルの調節とDSCGの抗アレルギー作用の新規メカニズム(シンポジウム:アレルギー炎症反応におけるヒスタミンと抗ヒスタミン薬)2007

    • Author(s)
      服部裕一, 松田直之
    • Organizer
      日本薬学会第127年会
    • Place of Presentation
      富山
    • Year and Date
      2007-03-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Role of histamine H4 receptors in key organs in sepsis2007

    • Author(s)
      Matsuda, N, Hattori, Y
    • Organizer
      The 11th Annual Meeting of the Japan Histamine Research Society
    • Place of Presentation
      Toyama
    • Year and Date
      2007-12-15
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Potential usefulness of FADD siRNA for gene therapy of septic acute lung injury2007

    • Author(s)
      Matsuda, N, Hattori, Y,, et. al.
    • Organizer
      The 58th North Area Meeting of the Japanese Pharmacological Society
    • Place of Presentation
      Sapporo
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Prevention of sepsis-induced acute lung injury by small interfering RNA for inhibition of tissue factor expression2006

    • Author(s)
      Matsuda N, Hattori Y, et. al.
    • Organizer
      Society of Critical Care Medicine 34th Critical Care Congress
    • Place of Presentation
      San Francisco
    • Year and Date
      2006-01-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] siRNA targeting caspase-3 and -8 prevents endothelial cell derangements in septic mouse2006

    • Author(s)
      Matsuda, N, Hattori, Y, Gando, S
    • Organizer
      European Society of Intensive Care Medicine 19th Annual Congress
    • Place of Presentation
      Barcelona
    • Year and Date
      2006-09-27
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Prevention of sepsis-induced acute lung injury by small interfering RNA For inhibition of tissue factor expression2006

    • Author(s)
      Matsuda, N, Hattori, Y, Takahashi, Y, Gando, S
    • Organizer
      Society of Critical Care Medicine 34th Critical Care Congress
    • Place of Presentation
      San Francisco
    • Year and Date
      2006-01-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Pro-apoptotic gene silencing in septic mouse aorta by small interfering RNA2006

    • Author(s)
      Matsuda N, Yamazaki M, Hattori Y
    • Organizer
      2006 Annual Meeting of American Society of Anesthesi-ologists the Special ASCCA/Journal Session
    • Place of Presentation
      Chicago
    • Year and Date
      2006-10-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] Pro-apoptotic gene silencing in septic mouse aorta by small interfering RNA2006

    • Author(s)
      Matsuda, N, Yamazaki, M, Hattori, Y
    • Organizer
      2006 Annual Meeting of American Society of Anesthesiologists the Special ASCCA/ Journal Session
    • Place of Presentation
      Chicago
    • Year and Date
      2006-10-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] siRNA targeting caspase-3 and -8 prevents endothelial cell derange-ments in septic mice2006

    • Author(s)
      Matsuda N, Hattori Y, Gando S
    • Organizer
      European Society of Intensive Care Medicine 19th Annual Congress
    • Place of Presentation
      Barcelona
    • Year and Date
      2006-09-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590233
  • [Presentation] レボシメンダンの抗炎症メカニズムにおけるHMGB1の役割

    • Author(s)
      高階道徳、横尾宏毅、服部裕一、他
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-24590315
  • 1.  MATSUDA Naoyuki (50332466)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 44 results
  • 2.  GANDO Satoshi (30125306)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 3.  YOKOO Hiroki (30332894)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 61 results
  • 4.  MIWA Soichi (40157706)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  TAKANO Yasuo (60142022)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 6.  YAMAMOTO Seiji (10456361)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 88 results
  • 7.  Ohashi Wakana (50381596)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 8.  FUKAO Mitsuhiro (10250432)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  NAGAI Yoshinori (30431761)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 21 results
  • 10.  佐久間 一郎 (40260393)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  TOMITA Fumishi (40271655)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KOHYA Tetsuro (70205350)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TAKIKAWA Osamu (70163342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  HAYASHI Yukio (60294063)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KAMIBAYASHI Takahiko (10273640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MASHIMO Takashi (60157188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  Watanabe Yasuhide (50305380)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  富樫 廣子 (20113590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  吉岡 充弘 (40182729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  冨田 賢吾 (20758213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 21.  鈴木 登紀子 (10415531)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 22.  井村 穣二 (80316554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 23.  町田 拓自 (90433424)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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