KAKUTA TAKATOSHI 角田隆俊

… Alternative Names

KAKUTA Takatoshi 角田隆俊

角多隆俊カクタタカトシ

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Researcher Number	50276854
Other IDs
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Affiliation (based on the past Project Information) *help	2020 – 2023: 東海大学, 医学部, 教授 2015 – 2018: 東海大学, 医学部, 教授 2009 – 2014: Tokai University, 医学部, 准教授 2005 – 2006: 東海大学, 医学部, 講師 2000 – 2002: 東海大学, 医学部, 講師 … More 1996: 東海大学, 医学部, 助手 1995: Tokai University School of Medicine, Transplantation I Assistant researcher, 医学部・移植学教室I, 助手 1995: 東海大学, 医学部・移植学教室I, 講師 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related / Urology Except Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related / Urology / General surgery / Kidney internal medicine
Keywords	Principal Investigator 腹膜透析 / ピリドキサミン / 二次性副甲状腺機能亢進症 / ARB / カルボニルストレス / AGE / 慢性腎不全 / 脂肪分化 / 内分泌学 / 副甲状腺 … More / 細胞増殖 / 副甲状腺機能亢進症 / 副甲状腺細胞 / pendisidine / pyrazolinones-polyethyleneimine / bead / Pyridoxamine / advanced glycation end products / effective peritoneal surface area / peritoneal Dialysis / トランスジェニックラット / 腹腔透析 / グリオキサラーゼI / ペントシジン / TM2002 / エダラボン / グリオキサラーゼ1 / 腹膜機能不全 / 半減期 / carbonyl / カルボニル・ストレス / 内服薬 / 腹膜保護 / 終末化糖産物(AGE) / 被嚢性硬化性腹膜炎(EPS) / メチルグリオキサール / カルボニル化合物 / 最終糖化産物 / 急性拒絶反応 / 99mTc-DTPA / 分腎機能 / Rutland法 / 因子分析法 … More Except Principal Investigator osteoprotegerin / PTH / ^<99m>Tc-DTPA / 二次性副甲状腺機能亢進症 / 副甲状腺機能亢進症 / バイオマーカー / 次世代シークエンサー / 慢性腎臓病 / 次世代シーケンサー / microRNA / vitamin D / uremic toxins / Bone metabolism / renal failure / ビタミンK2 / whole / Osteoprotegerin / ビタミンD / 尿毒物質 / 骨代謝 / 腎不全 / Bioartificial Kidney / Artifickal membrane / Gene transfection / Aquaporin 1 DNA / LLC-PK1 cells / Hybrid artificial tubules / Tubular epithelial cells / アクアポリン1 / ハイブリッド人工尿細胞 / バイオ人工腎臓 / 人工膜 / 遺伝子導入 / アクアポリン1遺伝子 / LLC-PK_1細胞 / ハイブリッド人工尿細管 / 尿細管上皮細胞 / Dynamic images / Renal graft function / Renal transplant / Glomerular filtration rate / Rutland method / Factor analysis / ^<99m>Tc-DAPA / 因子分析法 / Rut land法 / 移植腎機能 / GFR / 移植腎機能評価 / Rutland処理 / 因子分析 / ミネラル代謝 / 腎移植 / Klotho / 副甲状腺ホルモン / RNA干渉 / ＲＮＡ干渉 Less

Analysis of mechanism of adipose differentiation around hyperplastic parathyroidsPrincipal Investigator
- Principal Investigator
  
  KAKUTA TAKATOSHI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Tokai University
Analysis of functional RNA in parathyroid tumorigenesis associated with kidney disease
- Principal Investigator
  
  Kanai Genta
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Tokai University
Deveopment of methods to establish cell-line of parathyroid cellsPrincipal Investigator
- Principal Investigator
  
  KAKUTA Takatoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokai University
Examination of pharmacokinetics and pharmacodynamics of pyridoxamine as a protective agent of peritoneal membranePrincipal Investigator
- Principal Investigator
  
  KAKUTA Takatoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokai University
Influence of Klotho produced from transplanted kidneys on mineral metabolism and graft/patient survival in kidney transplant patients
- Principal Investigator
  
  NAKAMURA Michio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokai University
Development of the parathyroid hormone production controlling method by the RNA interference in consideration of clinical application
- Principal Investigator
  
  TANAKA Reika
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokai University
Research for the progression of encapsulating peritoneal sclerosisPrincipal Investigator
- Principal Investigator
  
  KAKUTA Takatoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokai University
Inhibition of intra-peritoneal carbonyl stress by carbonyl adsorbing beads or carbonyl stress inhibitorPrincipal Investigator
- Principal Investigator
  
  KAKUTA Takatoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokai University
Pathogenesis of Bone Diseases in Chronic Renal Failure
- Principal Investigator
  
  FUKAGAWA Masafumi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kobe University
Development of Hybrid Bioartificial Tubules using Tubular Epithelial Cells
- Principal Investigator
  
  SAITO Akira
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokai University
因子分析を応用したRutland法による腎機能評価の応用-病態の鑑別を中心として-Principal Investigator
- Principal Investigator
  
  角田隆俊
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Urology
- Research Institution
  Tokai University
EVALUATION OF RENAL GRAFT FUNCTION WITH RADIONUCLIDE DYNAMIC IMAGES -With Special Reference to the Application of the ModifiedRutland's Analytical Method-
- Principal Investigator
  
  HIRAGA Seigo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Department of Transplantation I, Tokai University School of Medicine

All 2024 2023 2022 2021 2016 2015 2011 2007 2005 Other

All Journal Article Presentation Patent

[Journal Article] Association of serum sodium levels with fractures and mortality in patients undergoing maintenance hemodialysis2024
- Author(s)
  Soeda Keisuke、Komaba Hirotaka、Nakagawa Yosuke、Kawabata Chiaki、Wada Takehiko、Takahashi Hiroo、Takahashi Yuichiro、Hyodo Toru、Hida Miho、Suga Takao、Kakuta Takatoshi、Fukagawa Masafumi
- Journal Title
  
  Journal of Nephrology
  
  Volume: - Issue: 5 Pages: 1339-1349
- DOI
  10.1007/s40620-024-01904-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08321, KAKENHI-PROJECT-21K08237
[Journal Article] Evaluation of ABCG2-mediated extra-renal urate excretion in hemodialysis patients2023
- Author(s)
  Ohashi Yuki、Toyoda Masao、Saito Nobumichi、Koizumi Masahiro、Kanai Genta、Komaba Hirotaka、Kimura Moritsugu、Wada Takehiko、Takahashi Hiroo、Takahashi Yuichiro、Ishida Naoto、Kakuta Takatoshi、Fukagawa Masafumi、Ichida Kimiyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 93-93
- DOI
  10.1038/s41598-022-26519-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08321, KAKENHI-PROJECT-20K17295, KAKENHI-PROJECT-21K08237
[Journal Article] 【二次性副甲状腺機能亢進症(SHPT)治療のパラダイムシフト】SHPTに対する副甲状腺摘出術2023
- Author(s)
  角田隆俊
- Journal Title
  
  泌尿器外科
  
  Volume: 36 Pages: 1306-1310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08237
[Journal Article] 副甲状腺の不思議とそのコントロール2021
- Author(s)
  角田隆俊
- Journal Title
  
  神奈川県臨床工学技士会誌
  
  Volume: 33 Pages: 46-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08237
[Journal Article] 【腎疾患治療薬update】(第2章)慢性腎臓病・透析合併症　CKD-MBD治療薬　カルシミメティクス　シナカルセト2021
- Author(s)
  角田隆俊
- Journal Title
  
  腎と透析
  
  Volume: 91増 Pages: 251-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08237
[Journal Article] Oral administration of pyridoxamine lower peritoneal carbonyl stress in uremic rats2016
- Author(s)
  Mori Y, Kakuta T, Miyakogawa T, Takekoshi S, Yuzawa H, Kobayashi H, Kawakami A, van Ypersele de Strihou C, Fukagawa M
- Journal Title
  
  Therapeutic Apheresis and Dialysis
  
  Volume: 20
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461256
[Journal Article] Mineral and bone disorders in kidney transplant recipients: Reversible, irreversible, and de novo abnormalities2015
- Author(s)
  Hirukawa T, Kakuta T, Nakamura M, Fukagawa M
- Journal Title
  
  Clin Ex Nephrol
  
  Volume: 19 Issue: 4 Pages: 543-555
- DOI
  10.1007/s10157-015-1117-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461962
[Journal Article] Effect of Sevelamer and Calcium-Based Phosphate Binders on Coronary Artery Calcification and Accumulation of Circulating Advvanced Glycation End Products in Hemodialysis Patients2011
- Author(s)
  Kakuta, R. Tanaka, T. Hyoudou, H. Suzuki, G. Kanai, M. Nagaoka, H. Takahashi, N. Hirawa, Y. Ogushi, T. Miyata, H. Kobayashi, M. Fukagawa, A. Saito
- Journal Title
  
  Am J Kidney Dis
  
  Volume: 57(3) Pages: 422-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591062
[Journal Article] Effect of Sevelamer and Calcium-Based Phosphate Binders on Coronary Artery Calcification and Accumulation of Circulating Advanced Glycation End Products in Hemodialysis Patients2011
- Author(s)
  角田隆俊
- Journal Title
  
  Am J Kidney Dis
  
  Volume: 57(3) Pages: 422-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591062
[Journal Article] Carbonyl stress reduction in peritoneal dialysis fluid : development of a novel high affinity adsorption bead2007
- Author(s)
  Makoto Yamamoto, Yuko Izuhara, Takatoshi Kakuta, Shunya Takizawa, Akio Fujita, Tatsuhiko Higaki, Charles van Ypersele de Strihou, Toshio Miyata
- Journal Title
  
  PD international (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590847
[Journal Article] Pyridoxamine improves functional, structural, and biochemical alterations of peritoneal membranes in nephrectomized uremic rats on peritoneal dialysis'2005
- Author(s)
  Takatoshi Kakuta, Reika Tanaka, Yoshinobu Satoh, Yuko Izuhara, Reiko Inagi, Masaomi Nanngaku, Akira Saito, Toshio Miyata
- Journal Title
  
  Kidney Int. 68
  
  Pages: 1326-1336
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590847
[Journal Article] Pyridoxamine improves functional, structural, and biochemical alterations of peritoneal membranes in uremic peritoneal dialysis rats2005
- Author(s)
  Takatoshi Kakuta
- Journal Title
  
  Kidney International Vol.68
  
  Pages: 1326-1336
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590847
[Patent] 腹膜保護剤2005
- Inventor(s)
  宮田敏夫, 角田隆俊
- Industrial Property Rights Holder
  学校法人東海大学
- Filing Date
  2005-05-24
- Data Source
  KAKENHI-PROJECT-17590847
[Patent] 腹膜保護剤
- Inventor(s)
  宮田敏男, 角田隆俊
- Industrial Property Rights Holder
  学校法人東海大学
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590847
[Presentation] 副甲状腺に発現する遺伝子群のリンによる調節とカルシミメティクスの効果2023
- Author(s)
  石田真理, 澤田佳一郎, 中澤来馬, 都川貴代, 中村道郎, 平光高久, 岡田学, 一森敏弘, 深川雅史, 角田隆俊
- Organizer
  日本透析医学界
- Data Source
  KAKENHI-PROJECT-21K08237
[Presentation] 二次性副甲状腺機能亢進症における遺伝子発現調節機序の解析2023
- Author(s)
  金井厳太, 澤田佳一郎, 角田隆俊, 深川雅史
- Organizer
  日本透析医学界
- Data Source
  KAKENHI-PROJECT-21K08237
[Presentation] 高齢腎不全患者における腎代替療法の選択2023
- Author(s)
  石田真理、角田隆俊
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-21K08237
[Presentation] 簡易化された手法によるiPS細胞からの副甲状腺分化細胞の作製2022
- Author(s)
  石田真理、都川貴代、中澤来馬、澤田佳一郎、角田隆俊
- Organizer
  日本透析医学会
- Data Source
  KAKENHI-PROJECT-21K08237

1. KANAI Genta (00535221)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. SAWADA Kaichiro (10420952)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. FUKAGAWA Masafumi (00211516)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. TANAKA Reika (10372947)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. KOBAYASHI Hiroyuki (60195807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. NAKAMURA Michio (00246547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. SHIRAI Hiroyuki (90346338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HIRAGA Seigo (10114779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IIDA Takashi (10193137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HIDA Miho (20147169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KITAMURA Makoto (00214817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAITO Akira (60307296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KIMURA Minoru (10146706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKAZAWA Hiroe (20110885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MIYATA Toshio (10222332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 時政孝行 (50155511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MORIYA Hitomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. WADA Takehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 豊田雅夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAKUTA TAKATOSHI 角田 隆俊

KAKUTA Takatoshi 角田 隆俊

角多 隆俊 カクタ タカトシ

Research Projects

Research Products

Co-Researchers

Analysis of mechanism of adipose differentiation around hyperplastic parathyroidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of functional RNA in parathyroid tumorigenesis associated with kidney disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Deveopment of methods to establish cell-line of parathyroid cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Examination of pharmacokinetics and pharmacodynamics of pyridoxamine as a protective agent of peritoneal membranePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Influence of Klotho produced from transplanted kidneys on mineral metabolism and graft/patient survival in kidney transplant patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the parathyroid hormone production controlling method by the RNA interference in consideration of clinical application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for the progression of encapsulating peritoneal sclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inhibition of intra-peritoneal carbonyl stress by carbonyl adsorbing beads or carbonyl stress inhibitorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathogenesis of Bone Diseases in Chronic Renal Failure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Hybrid Bioartificial Tubules using Tubular Epithelial Cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

因子分析を応用したRutland法による腎機能評価の応用-病態の鑑別を中心として-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EVALUATION OF RENAL GRAFT FUNCTION WITH RADIONUCLIDE DYNAMIC IMAGES -With Special Reference to the Application of the ModifiedRutland's Analytical Method-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association of serum sodium levels with fractures and mortality in patients undergoing maintenance hemodialysis2024

Author(s)

KAKUTA TAKATOSHI 角田隆俊

KAKUTA Takatoshi 角田隆俊

角多隆俊カクタタカトシ

[Journal Article] 【腎疾患治療薬update】(第2章)慢性腎臓病・透析合併症　CKD-MBD治療薬　カルシミメティクス　シナカルセト2021