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Arai Yuji  新井 祐志

ORCIDConnect your ORCID iD *help
… Alternative Names

ARAI Yuji  新井 祐志

NAKAMURA Naoto  中村 直登

TAKAHASHI Kenji  高橋 謙治

新井 佑志

新井 祐志  アライ ユウジ

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Researcher Number 50347449
Other IDs
Affiliation (Current) 2022: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help 2016 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
2012 – 2016: 京都府立医科大学, 医学研究科, 講師
2011 – 2015: 京都府立医科大学, 医学(系)研究科(研究院), 講師
2013: 京都府立医科大学, 医学研究科, 教授
2013: 京都府立医科大学, 医学部, 講師 … More
2010: 京都府立医科大学, 医学研究科, 講師
2008 – 2009: 京都府立医科大学, 医学研究科, 助教
2007 – 2009: Kyoto Prefectural University of Medicine, 医学部, 助教
2007: 京都府立大学, 医学部, 助教
2006: 京都府立医科大学, 医学部, 助教(寄附講座)
2003: 京都府立医大, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Rehabilitation science/Welfare engineering / Basic Section 59010:Rehabilitation science-related
Except Principal Investigator
Orthopaedic surgery / Basic Section 59010:Rehabilitation science-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Biological pharmacy / Drug development chemistry / Basic Section 56020:Orthopedics-related / Metabolomics / Rehabilitation science/Welfare engineering / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
変形性関節症 / HIF-1α / 軟骨 / 低酸素 / 低酸素環境 / 整形外科 / リハビリテーション / small interfering RNA / 関節滑膜 / ADAMTS-5 … More / 動物モデル / sonoporation / 関節軟骨 / 滑膜 / ミオスタチン / hiPS細胞 / 筋芽細胞 / siRNA / 筋力訓練 / hyaluronic acid / CD44 / articular cartilage / extracellular matrix / hypoxia / ヒアルロン酸 / 細胞外マトリックス / 高分子ヒアルロン酸 / HSP70 / メカニカルストレス / 伸展刺激 / 運動療法 / 軟骨代謝 / ストレス … More
Except Principal Investigator
関節リウマチ / CD81 / 変形性関節症 / 低酸素 / テトラスパニン / 軟骨 / 再生医療 / HSP70 / 骨肉腫 / 整形外科学 / サルコペニア / シノビオリン / heat shock protein 70 / 炎症性サイトカイン / アポトーシス / iPS細胞 / 骨軟骨代謝学 / 骨芽細胞 / 再生医学 / 滑膜細胞 / ストレス応答機構 / グルタミン / 関節疾患 / siRNA / モノクローナル抗体 / ダイレクトコンヴァージョン / 温熱療法 / 関節軟骨 / 軟骨細胞 / メカニカルストレス / 軟骨代謝 / 遺伝子治療 / ヒアルロン酸 / ダイレクト・コンヴァージョン / フレイル / リハビリテーション / ダイレクト・リプログラミング / リウマチ / DNAチップ / 温熱 / マイクロウェーブ / 低酸素誘導因子 / 骨形成因子 / サンドイッチELISA / TNFalpha / グリア細胞 / ELISA / 糖脂質代謝 / メタボリックシンドローム / 褐色脂肪細胞 / メタボリックシンドローム / メタボリックシンドローム / 微弱電流刺激 / ユビキチン化タンパク / リウマチ病学 / コネキシン43 / ギャップ結合 / 破骨細胞 / 滑膜炎 / コネキシン / ストレス応答 / 概日リズム / リプログラミング / 炎症生サイトカイン / 化学療法 / シスプラチン / Hsp70 / Hsp70 / SiRNA / 温熱刺激 / 分子標的治療薬 / 骨肉腫制御 / 分子標的治療 / テトラスパニンファミリー / HIF-1α / 幹細胞 / 物理刺激 / 軟骨分化 / 硝子軟骨 / 骨粗鬆症 / 骨・軟骨代謝学 / キメラ抗体 / 遺伝子クローニング / 間接リウマチ / プリスチメリン / 細胞増殖抑制効果 / テルペノイド / 天然有機化合物 / カスパーゼ / 天然化合物 / 運動療法 / カチオン化 / 骨格筋細胞 / 3次元培養 / バイオマイクロシステム / 老化 / 身体活動量 / 高齢者 / 麻痺性疾患 / 炎症性疾患 / 健康づくりのための身体活動基準 / 定量化 / 筋肉量 / HYBID / 頭頚部がん / 乳がん / 免疫染色 / エクソソーム / 整形外科 / CIAラット / ベルト電極式骨格筋電気刺激法 / 電気刺激 / 骨疾患 Less
  • Research Projects

    (34 results)
  • Research Products

    (154 results)
  • Co-Researchers

    (38 People)
  •  Establishment of a new exercise therapy for osteoarthritis using HIF-1alpha regulation by hypoxiaPrincipal Investigator

    • Principal Investigator
      新井 祐志
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of the next generation OA hyperthermia using a novel photothermal DDS

    • Principal Investigator
      高橋 謙治
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Prevention of Skeletal Muscle Fibrosis by a Novel Electrical Stimulation Method - Development of an Effective Treatment for Secondary Sarcopenia-

    • Principal Investigator
      遠山 将吾
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of low-load exercise therapy using molecular biological techniques for rheumatoid arthritis with sarcopenia

    • Principal Investigator
      中川 周士
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Regenerative therapeutics of bone diseases by means of in situ direct reprogramming

    • Principal Investigator
      松田 修
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  低酸素環境での新規分子HYBIDの制御による変形性関節症治療法の開拓

    • Principal Investigator
      井上 裕章
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of anti-tumor drugs targeting CD81

    • Principal Investigator
      中西 徹
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Shujitsu University
  •  筋老化の分子機構解明の為の3D培養骨格筋組織の開発

    • Principal Investigator
      岸田 綱郎
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  リハビリテーションの質を可視化するー健康長寿に向けた負荷量見える化の試みー

    • Principal Investigator
      徳永 大作
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Regeneration of bone and cartilage tissues by means of chemical direct reprogramming

    • Principal Investigator
      Osam Mazda
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of exercise therapy for rheumatoid arthritis by controlling hypoxia-inducible factor

    • Principal Investigator
      中川 周士
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of charge based DDS for OA based on the negative charge of aggrecan

    • Principal Investigator
      Kubo Toshikazu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of novel gene therapy for rheumatoid arthritis

    • Principal Investigator
      Nakanishi Tohru
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Shujitsu University
  •  Development of a novel therapeutic drug for osteosarcoma using pristimerin

    • Principal Investigator
      Terauchi Ryu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of HIF-1a-induced exercise therapy focusing on the intra-articular hypoxic environmentPrincipal Investigator

    • Principal Investigator
      Arai Yuji
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of a new method for regenerating hyaline cartilage using a bioreactor for iPS cells

    • Principal Investigator
      Kubo Toshikazu
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of novel anti-cancer drug targeting CD81 of osteosarcoma

    • Principal Investigator
      Shirai Toshiharu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of new OA therapy targeting HIF-1a

    • Principal Investigator
      Kubo Toshikazu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of novel therapeutic compounds for rheumatoid arthritis targeting CD81

    • Principal Investigator
      Nakanishi Tohru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Shujitsu University
  •  Development of stump treatment method using heat shock protein inhibition technique for sarcoma

    • Principal Investigator
      Terauchi Ryu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Investigation of stress response mechanism of chondrocytes by reproduction of physiological hypoxic environmentPrincipal Investigator

    • Principal Investigator
      Arai Yuji
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Pathogenesis and regenerative therapy of osteoporosis

    • Principal Investigator
      Mazda Osam
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  crosstalk between stress response and the circadian rhythm in cartilage

    • Principal Investigator
      KUBO TOSHIKAZU
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Bone regeneration based on direct reprogramming technologies

    • Principal Investigator
      MAZDA Osam
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  New development of the molecular targeted therapy for osteoarthritis arthritis with respect to stress-response mechanism

    • Principal Investigator
      Kubo Toshikazu
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Reclamation of a novel OA therapy by the control of MyostatinPrincipal Investigator

    • Principal Investigator
      ARAI Yuji
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of novel antibody therapy targeting tetraspanin CD81

    • Principal Investigator
      NAKANISHI Tohru
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Shujitsu University
  •  Toward novel molecular targeting strategies for the metabolic syndrome

    • Principal Investigator
      KISHIDA Tsunao
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The analysis of thermotherapy combined with drugs for osteoarthritis

    • Principal Investigator
      KUBO Toshikazu
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Possibility of connexin43 as a new therapeutic target for rheumatoid arthritis

    • Principal Investigator
      TERAUCHI Ryu
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The analysis of cellular stress response towards novel conservative therapies for joint disease

    • Principal Investigator
      KUBO Toshikazu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Isolation and identification of CD81 as a novel target for treatment of rheumatoid arthritis.

    • Principal Investigator
      NAKANISHI Tohru
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Shujitsu University
  •  関節軟骨へのsiRNA導入法の確立-変形性関節症の新しい保存療法の開発へ向けて-Principal Investigator

    • Principal Investigator
      新井 祐志
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  変形性関節症および軟骨損傷に対する線維芽細胞を用いた遺伝子治療の開発Principal Investigator

    • Principal Investigator
      新井 祐志
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

  • [Book] 別冊BIO Clinica 慢性炎症と疾患2016

    • Author(s)
      中西 徹、山崎 勤、新井祐志、中川周士、久保俊一
    • Total Pages
      168
    • Publisher
      北隆館
    • Data Source
      KAKENHI-PROJECT-26460165
  • [Book] 生体電気・物理刺激による骨・軟部組織修復法(温熱刺激による変形性関節症の進行抑制効果)2012

    • Author(s)
      新井祐志,土田真嗣,藤田伸弥
    • Total Pages
      304
    • Publisher
      金芳堂
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Journal Article] Direct conversion of human fibroblasts into adipocytes using a novel small molecular compound: implications for regenerative therapy for adipose tissue defects2021

    • Author(s)
      Yoshihiro Sowa *, Tsunao Kishida, Fiona Louis, Seiji Sawai, Seki Makoto, Kenji Takahashi, Toshiaki Numajiri, Osam Mazda
    • Journal Title

      Cells

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22690
  • [Journal Article] Treadmill running prevents atrophy differently in fast- versus slow-twitch muscles in a rat model of rheumatoid arthritis2021

    • Author(s)
      Yoichiro Kamada , Shogo Toyama , Yuji Arai , Hiroaki Inoue , Shuji Nakagawa , Yuta Fujii Kenta Kaihara , Tsunao Kishida , Osam Mazda , Kenji Takahashi
    • Journal Title

      Journal of Muscle Research and Cell Motility

      Volume: Dec;42(3-4) Pages: 429-441

    • DOI

      10.1007/s10974-021-09610-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11369, KAKENHI-PROJECT-19K19914, KAKENHI-PROJECT-21H03058, KAKENHI-PROJECT-21K19577
  • [Journal Article] Mechanical stimulation of chondrocytes regulates HIF-1α under hypoxic conditions2021

    • Author(s)
      Shimomura S, Inoue H, Arai Y, Nakagawa S, Fujii Y, Kishida T, Shin-Ya M, Ichimaru S, Tsuchida S, Mazda O, Takahashi K.
    • Journal Title

      Tissue and Cell

      Volume: Aug;71:101574. Pages: 101574-101574

    • DOI

      10.1016/j.tice.2021.101574

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11369, KAKENHI-PROJECT-21H03058, KAKENHI-PROJECT-20K11214, KAKENHI-PROJECT-21K19577
  • [Journal Article] Direct Conversion of Human Fibroblasts into Adipocytes Using a Novel Small Molecular Compound: Implications for Regenerative Therapy for Adipose Tissue Defects2021

    • Author(s)
      Sowa Y, Kishida T, Louis F, Sawai S, Seki M, Numajiri T, Takahashi K, Mazda O
    • Journal Title

      Cells .

      Volume: 10 Pages: 3390-3405

    • DOI

      10.3390/cells10030605

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09488, KAKENHI-PROJECT-19K11369, KAKENHI-PROJECT-21H03058, KAKENHI-PROJECT-21K19577
  • [Journal Article] Sustained Hypoxia Suppresses Joint Destruction in a Rat Model of Rheumatoid Arthritis via Negative Feedback of Hypoxia Inducible Factor-1α2021

    • Author(s)
      Kaihara Kenta、Nakagawa Shuji、Arai Yuji、Inoue Hiroaki、Tsuchida Shinji、Fujii Yuta、Kamada Yoichiro、Kishida Tsunao、Mazda Osam、Takahashi Kenji
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Pages: 3898-3898

    • DOI

      10.3390/ijms22083898

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10752, KAKENHI-PROJECT-21K11292
  • [Journal Article] ALK5 i II Accelerates Induction of Adipose-Derived Stem Cells toward Schwann Cells through a Non-Smad Signaling Pathway2021

    • Author(s)
      Seiji Sawai 1, Tsunao Kishida , Shin-Ichiro Kotani , Shinji Tsuchida , Ryo Oda , Hiroyoshi Fujiwara, Kenji Takahashi , Osam Mazda , Yoshihiro Sowa
    • Journal Title

      Stem Cells International

      Volume: Oct. 15 Pages: 1-11

    • DOI

      10.1155/2021/8307797

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11369, KAKENHI-PROJECT-21H03058, KAKENHI-PROJECT-21K19577
  • [Journal Article] Treadmill Running in Established Phase Arthritis Inhibits Joint Destruction in Rat Rheumatoid Arthritis Models2020

    • Author(s)
      Fujii Yuta、Inoue Hiroaki、Arai Yuji、Shimomura Seiji、Nakagawa Shuji、Kishida Tsunao、Tsuchida Shinji、Kamada Yoichiro、Kaihara Kenta、Shirai Toshiharu、Terauchi Ryu、Toyama Shogo、Ikoma Kazuya、Mazda Osam、Mikami Yasuo
    • Journal Title

      Int J Mol Sci.

      Volume: 20 Pages: 5100-5100

    • DOI

      10.3390/ijms20205100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K19914, KAKENHI-PROJECT-17H02136, KAKENHI-PROJECT-17H04316, KAKENHI-PROJECT-20K11214
  • [Journal Article] Pristimerin inhibits the proliferation of HT1080 fibrosarcoma cells by inducing apoptosis2020

    • Author(s)
      Hayashi Daichi、Shirai Toshiharu、Terauchi Ryu、Tsuchida Shinji、Mizoshiri Naoki、Mori Yuki、Arai Yuji、Mazda Osam、Kubo Toshikazu
    • Journal Title

      Oncology Letters

      Volume: 19 Pages: 2963-2970

    • DOI

      10.3892/ol.2020.11405

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22690
  • [Journal Article] Relationship of alignment in the lower extremity with early degeneration of articular cartilage after resection of the medial meniscus: Quantitative analysis using T2 mapping2020

    • Author(s)
      Nakagawa Shuji、Arai Yuji、Inoue Hiroaki、Fujii Yuta、Kaihara Kenta、Mikami Yasuo
    • Journal Title

      Medicine

      Volume: 99

    • DOI

      10.1097/md.0000000000022984

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10752, KAKENHI-PROJECT-18K16630
  • [Journal Article] Clinical outcomes after medial patellofemoral ligament reconstruction: an analysis of changes in the patellofemoral joint alignment2020

    • Author(s)
      Fujii Yuta、Nakagawa Shuji、Arai Yuji、Inoue Hiroaki、Kan Hiroyuki、Hino Manabu、Kaihara Kenta、Mikami Yasuo
    • Journal Title

      International Orthopaedics

      Volume: -

    • DOI

      10.1007/s00264-020-04765-w

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10752
  • [Journal Article] Construction of an expression vector containing mouse-rat chimeric genes encoding a therapeutic antibody against CD812019

    • Author(s)
      Yamasaki T, Arai Y, Nakagawa S, Kubo T, Nakanishi T
    • Journal Title

      J Hard Tissue Biol

      Volume: 28 Pages: 239-244

    • NAID

      130007685302

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08379
  • [Journal Article] The tetraspanin CD81 mediates the growth and metastasis of human osteosarcoma2019

    • Author(s)
      Mizoshiri N, Shirai T, Terauchi R, Tsuchida S, Mori Y, Hayashi D, Kishida T, Arai Y, Nakanishi T, Kubo T
    • Journal Title

      Cell Oncol

      Volume: on line

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08379
  • [Journal Article] Construction of an Expression Vector Containing Mouse-Rat Chimeric Genes Encoding a Therapeutic Antibody against CD812019

    • Author(s)
      Tsutomu Yamasaki, Yuji Arai, Shuji Nakagawa, Toshikazu Kubo and Tohru Nakanishi
    • Journal Title

      J Hard Tissue Biol

      Volume: in press

    • NAID

      130007685302

    • Data Source
      KAKENHI-PROJECT-17K08379
  • [Journal Article] The Usefulness of Basic Movement Scale in Hip Fracture Patients2019

    • Author(s)
      Goto Ryutaro、Toyama Shogo、Sawada Koshiro、Takamuku Kiyoshi、Kubo Toshikazu、Takahashi Tai
    • Journal Title

      American Journal of Physical Medicine & Rehabilitation

      Volume: 98 Pages: 1099-1105

    • DOI

      10.1097/phm.0000000000001254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K11420
  • [Journal Article] The tetraspanin CD81 mediates the growth and metastases of human osteosarcoma2019

    • Author(s)
      Mizoshiri Naoki、Shirai Toshiharu、Terauchi Ryu、Tsuchida Shinji、Mori Yuki、Hayashi Daichi、Kishida Tsunao、Arai Yuji、Mazda Osam、Nakanishi Tohru、Kubo Toshikazu
    • Journal Title

      Cellular Oncology

      Volume: 42 Pages: 861-871

    • DOI

      10.1007/s13402-019-00472-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H02136, KAKENHI-PROJECT-17H04316
  • [Journal Article] Treadmill Running Ameliorates Destruction of Articular Cartilage and Subchondral Bone, Not Only Synovitis, in a Rheumatoid Arthritis Rat Model2018

    • Author(s)
      Shimomura S, Inoue H, Arai Y, Nakagawa S, Fujii Y, Kishida T, Ichimaru S, Tsuchida S, Shirai T, Ikoma K, Mazda O, Kubo T.
    • Journal Title

      Int J Mol Sci.

      Volume: 19 Pages: 1653-1653

    • DOI

      10.3390/ijms19061653

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10752, KAKENHI-PROJECT-17H02136, KAKENHI-PROJECT-16K15669, KAKENHI-PROJECT-17H04316
  • [Journal Article] Suppression of heat shock protein 70 by siRNA enhances the anti-tumor effects of cisplatin in cultured human osteosarcoma cells2017

    • Author(s)
      Mori Y. et al.
    • Journal Title

      Cell Stress and Chaperones

      Volume: in press

    • DOI

      10.1007/s12192-017-0793-x

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293340, KAKENHI-PROJECT-26462273
  • [Journal Article] テトラスパニンCD81を標的とする新規次世代リウマチ治療薬の開発2016

    • Author(s)
      中西 徹、山崎 勤、新井祐志、中川周士、久保俊一
    • Journal Title

      アレルギーの臨床

      Volume: 36 Pages: 1382-1387

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460165
  • [Journal Article] Hypoxia potentiates anabolic effects of exogenous hyaluronic acid in rat articular cartilage.2016

    • Author(s)
      Ichimaru S. et al.
    • Journal Title

      International Journal of Molecular Science

      Volume: 17

    • DOI

      10.3390/ijms17071013

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293340, KAKENHI-PROJECT-26462312, KAKENHI-PROJECT-15K15555
  • [Journal Article] Hydrostatic Pressure Influences HIF-2 Alpha Expression in Chondrocytes2015

    • Author(s)
      Hiroaki Inoue, Yuji Arai, Tsunao Kishida, Ryu Terauchi, Kuniaki Honjo, Shuji Nakagawa, Shinji Tsuchida, Tomohiro Matsuki, Keiichirou Ueshima, Hiroyoshi Fujiwara, Osam Mazda, Toshikazu Kubo
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 16 Pages: 1043-1050

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Journal Article] Sonoporation-mediated transduction of siRNA ameliorated experimental arthritis using 3 MHz pulsed ultrasound.2014

    • Author(s)
      Inoue H, Arai Y, Kishida T, Shin-Ya, M, Terauchi R, Nakagawa S, Saito M, Tsuchida, S, Inoue A, Shirai T, Fujiwara H, Mazda O, Kubo T
    • Journal Title

      Ultrasonics

      Volume: 54(3)(Epub 2013 Nov 11) Pages: 874-81

    • DOI

      10.1016/j.ultras.2013.10.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-24390356
  • [Journal Article] HIF-1a-Induced HSP70 Regulates Anabolic Responses in Articular Chondrocytes under Hypoxic Conditions2014

    • Author(s)
      Tsuchida S, Arai Y, Takahashi KA, Kishida T, Terauchi R, Honjo K, Nakagawa S, Inoue H, Ikoma K, Ueshima K, Matsuki T, Mazda O, Kubo T
    • Journal Title

      Orthop Res

      Volume: (Epub ahead of print) Pages: 975-80

    • DOI

      10.1002/jor.22623

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/24677016

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-26293340, KAKENHI-PROJECT-26462312, KAKENHI-PROJECT-26670452, KAKENHI-PROJECT-26670485
  • [Journal Article] Silencing the expression of connexin 43 decreases inflammation and joint destruction in experimental arthitis.2013

    • Author(s)
      Tsuchida S, Arai Y, Kishida T, Takahashi K, Honjo K, Terauchi R, Inoue H, Oda R, Mazda O, Kubo T.
    • Journal Title

      J. Orthop. Res

      Volume: 31(4) Pages: 525-30

    • DOI

      10.1002/jor.22263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-23659731, KAKENHI-PROJECT-24659447, KAKENHI-PROJECT-25670656
  • [Journal Article] Silencing the expression of connexin 43 decreases inflammation and joint destruction in experimental arthritis.2013

    • Author(s)
      Tsuchida S, Arai Y, Kishida T, Takahashi KA, Honjo K, Terauchi R, Inoue H, Oda R, Mazda O, Kubo T.
    • Journal Title

      Journal of Orthopaedic Reseach

      Volume: 31(4) Pages: 525-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659731
  • [Journal Article] MIld electrical stimulation with stimulation increace heat shock protein 70 in articular chondrocyte.2013

    • Author(s)
      Hiraoka N,Arai Y, Takahashi KA, Mazda O, Kishida T, Honjo K, Tsuchida S, Inoue H, Morino S, Suico MA, Kai H, Kubo T.
    • Journal Title

      J. Orthop. Res.

      Volume: 17 Pages: 894-900

    • DOI

      10.1002/jor.22307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-23650333, KAKENHI-PROJECT-24659447, KAKENHI-PROJECT-25670260, KAKENHI-PROJECT-25670656
  • [Journal Article] Combined microwave irradiation and intraarticular glutamine administr ation-induced HSP70 expression therapy prevents cartilage degradation in a rat osteoarthritis model2012

    • Author(s)
      Shinya Fujita, Yuji Arai, Shuji Nakagawa, Kenji A.Takahashi, Ryu Terauchi, Atsuo Inoue, Hitoshi Tonomura, Nobuyuki Hiraoka, Hiroaki Inoue, Shinji Tsuchida, Osam Mazda, Toshikazu Kubo
    • Journal Title

      JOURNAL OF ORTHOPAEDIC RESEARCH

      Volume: 30 Pages: 401-407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Journal Article] Application of tetraspanin CD81 RNAi for diagnosis and therapy of rheumatoid arthritis (RA)2012

    • Author(s)
      Nakanishi T, Arai Y, Mori H, Nakajima T, Kubo T
    • Journal Title

      Arthr Res Therap

      Volume: 14 Pages: 52-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590102
  • [Journal Article] Lansoprazole Inhibits Nitric Oxide and Prostaglandin E(2) Production in Murine Macrophage RAW 264.7 Cells2012

    • Author(s)
      Nakagawa S, Arai Y, Kishida T, Hiraoka N, Tsuchida S, Inoue H, Sakai R, Mazda O, Kubo T
    • Journal Title

      Inflammation

      Volume: 35(3)(PMID :22134422)(PubMed - in process) Pages: 1062-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591318
  • [Journal Article] Combined microwave irradiation and intraarticular glutamine administration-induced HSP70 expression therapy prevents cartilage degradation in a rat osteoarthritis model2012

    • Author(s)
      Shinya Fujita, Yuji Arai, Shuji Nakagawa, Kenji A. Takahashi, Ryu Terauchi, Atsuo Inoue, Hitoshi Tonomura, Nobuyuki Hiraoka, Hiroaki Inoue, Shinji Tsuchida, Osam Mazda, Toshikazu Kubo
    • Journal Title

      Journal of Orthopaedic Reseach

      Volume: Vol.30 Pages: 401-407

    • URL

      http://onlinelibrary.wiley.com/doi/10.1002/jor.21535/abstract

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Journal Article] 3. Lansoprazole inhibits nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells.2012

    • Author(s)
      Shuji Nakagawa, Yuji Arai, Tsunao Kishida, Nobuyuki Hiraoka, Shinji Tsuchida, Hiroaki Inoue, Ryo Sakai, Osam Mazda, Toshikazu Kubo
    • Journal Title

      Inflammation.

      Volume: Vol.35 Pages: 1062-1068

    • DOI

      10.1007/s10753-011-9412-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659276, KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-24659447
  • [Journal Article] Application of tetraspanin CD81 RNAi for diagnosis and therapy of rheumatoid arthrits (RA)2012

    • Author(s)
      Nakanishi T, Arai Y, Mori H, Nakajima T, Kubo T
    • Journal Title

      Arthr Res Therap

      Volume: 14 Pages: 52-52

    • Data Source
      KAKENHI-PROJECT-23590102
  • [Journal Article] Intra-articular injection of hyaluronan restores the aberrant expression of matrix metalloproteinase-13 in osteoarthritic subchondral bone.2011

    • Author(s)
      Hiraoka N, Takahashi KA, Arai Y, Sakao K, Mazda O, Kishida T, Honjo K, Tanaka S, Kubo T
    • Journal Title

      J Orthop Res.

      Volume: 29(3) Pages: 354-60

    • DOI

      10.1002/jor.21240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591318
  • [Journal Article] N-Acetylcysteine Prevents Nitric Oxide-Induced Chondrocyte Apoptosis and Cartilage Degeneration in an Experimental Model of Osteoarthritis2010

    • Author(s)
      Shuji Nakagawa, Yuji Arai, Osam Mazda, Tsunao Kishida, Kenji A. Takahashi, Kei Sakao, Masazumi Saito, Kuniaki Honjo, Jiro Imanishi, Toshikazu Kubo
    • Journal Title

      Journal of Orthopaedic Reseach

      Volume: Vol.28 Pages: 156-163

    • URL

      http://onlinelibrary.wiley.com/doi/10.1002/jor.20976/abstract

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Journal Article] N-Acetylcysteine Prevents Nitric Oxide-Induced Chondrocyte Apoptosis and Cartilage Degeneration in an Experimental Model of Osteoarthritis2010

    • Author(s)
      Shuji Nakagawa, Yuji Arai, Osam Mazda, Tsunao Kishida, Kenji A.Takahashi, Kei Sakao, Masazumi Saito, Kuniaki Honjo, Jiro Imanishi, Toshikazu Kubo
    • Journal Title

      JOURNAL OF ORTHOPAEDIC RESEARCH

      Volume: 28 Pages: 156-163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Journal Article] Small interfering RNA targeting CD81 ameliorated arthritis in rats.2009

    • Author(s)
      Nakagawa S, Arai Y, Mori H, Matsushita Y, Kubo T, Nakanishi T
    • Journal Title

      Biochem Biophys Res Commun 388

      Pages: 467-472

    • Data Source
      KAKENHI-PROJECT-19390026
  • [Journal Article] Hyperthermia for the treatment of articular cartilage with osteoarthritis2009

    • Author(s)
      Kenji A. Takahashi, Hitoshi Tonomura, Yuji Arai, Ryu Terauchi, Kuniaki Honjo, Nobuyuki Hiraoka, Tatsuya Hojo, Taisuke Kunitomo, Toshikazu Kubo
    • Journal Title

      International Journal of Hyperthermia

      Volume: Vol.25, No8 Pages: 661-667

    • URL

      http://informahealthcare.com/doi/abs/10.3109/02656730903107519

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Journal Article] Hyperthermia for the treatment of articular cartilage with osteoarthritis2009

    • Author(s)
      Kenji A Takahashi, Toshikazu Kubo
    • Journal Title

      International Journal of Hyperthermia 25(8)

      Pages: 661-667

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Journal Article] Effects of heat stimulation via microwave applicator on cartilage matrix gene and HSP70 expression in the rabbit knee joint2008

    • Author(s)
      Hitoshi Tonomura, Kenji A. Takahashi, Osam Mazda, Yuji Arai, Masaharu Shin-Ya, Atsuo Inoue, Kuniaki Honjo, Tatsuya Hojo, Jiro Imanishi, Toshikazu Kubo
    • Journal Title

      Journal of Orthopaedic Reseach

      Volume: Vol.26 Pages: 34-41

    • URL

      http://onlinelibrary.wiley.com/doi/10.1002/jor.20421/abstract;jsessionid=C846DE7EF515F96FD6959D9EDB20BDBA.d03t02

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Journal Article] Comparison of anti-rheumatic effcts of Iocal siRNA therapy using various cytokine genes as molecular targets2008

    • Author(s)
      Inoue, A; Arai, Y.
    • Journal Title

      Transaction of Orthopaedic Research Society 33

      Pages: 1192-1192

    • Data Source
      KAKENHI-PROJECT-18791049
  • [Journal Article] The gene expression profile of ADAMTS-5 in the synovium of experimental osteoarthritis and gene silencing using small interfering RNA2008

    • Author(s)
      Saito, M; Arai, Y.
    • Journal Title

      Transaction of Orthopaedic Research Society 33

      Pages: 671-671

    • Data Source
      KAKENHI-PROJECT-18791049
  • [Journal Article] The therapeuitic effects of inflammatory cytokine-specific small interfering RNA transduction into joints on rat arthritis2007

    • Author(s)
      Inoue, A., Arai, Y.
    • Journal Title

      Transaction of Orthopaedic Research Society 32

      Pages: 1460-1460

    • Data Source
      KAKENHI-PROJECT-18791049
  • [Journal Article] The safe and effective delivery of small interfering RNA into the knee joints using sonoporation2007

    • Author(s)
      Saito, M., Arai, Y.
    • Journal Title

      Transaction of Orthopaedic Research Society 32

      Pages: 1461-1461

    • Data Source
      KAKENHI-PROJECT-18791049
  • [Journal Article] Hydrostatic pressure induces apoptosis of chondrocytes cultured in alginate beads2006

    • Author(s)
      Nakamura, S., Arai, Y
    • Journal Title

      Journal of Orthopaedic Research 24

      Pages: 733-739

    • Data Source
      KAKENHI-PROJECT-18791049
  • [Journal Article] Sonoporation mediated transduction of pDNA/siRNA into joint synovium in vivo

    • Author(s)
      Saito, M., Arai, Y.
    • Journal Title

      Journal of Orthopaedic Research (in press)

    • Data Source
      KAKENHI-PROJECT-18791049
  • [Presentation] 持続的な低酸素環境はラット関節炎モデルにおいて軟骨破壊を抑制する2022

    • Author(s)
      貝原 健太、中川 周士、井上 敦夫、新井 祐志、藤井 雄太、鎌田 陽一郎、車 龍太、 松田 修、高橋 謙治
    • Organizer
      第34回日本軟骨代謝学会
    • Data Source
      KAKENHI-PROJECT-21H03295
  • [Presentation] Analysis of muscle atrophy and fibrosis in fast and slow muscles in a rat model of arthritis2021

    • Author(s)
      Kamada Y, Toyama S, Inoue H, Nakagawa S, Fujii Y, Kaihara K, Arai Y, Mazda O, Takahashi K
    • Organizer
      2021 ORS annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10752
  • [Presentation] Influence of heat stress on SIRT1-transfected chondrocytes2021

    • Author(s)
      Kaihara K, Inoue H, Nakagawa S, Arai Y, Fujii Y, Mazda O, Takahashi K
    • Organizer
      2021 Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09507
  • [Presentation] Analysis of muscle atrophy and fibrosis in fast and slow muscles in a rat model of arthritis2021

    • Author(s)
      Kamada Y, Toyama S, Inoue H, Nakagawa S, Fujii Y, Kaihara K, Arai Y, Mazda O, Takahashi K
    • Organizer
      2021 ORS annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K11292
  • [Presentation] 酸素濃度がヒトiPS細胞から軟骨組織への分化に与える影響2021

    • Author(s)
      藤井雄太,井上裕章,下村征史,中川周士,市丸昌平,鎌田陽一郎,貝原健太,松田 修,新井祐志
    • Organizer
      第33回日本軟骨代謝学会
    • Data Source
      KAKENHI-PROJECT-18K19620
  • [Presentation] Influence of heat stress on SIRT1 transfected chondrocytes2021

    • Author(s)
      Kaihara K, Inoue H, Nakagawa S, Arai Y, Fujii Y, Kamada Y, Mazda O, Takahashi K
    • Organizer
      2021 OARSI annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10752
  • [Presentation] 持続的な低酸素環境は HIF-1α のネガティブフィードバックを介して炎症性サイトカインの産生を抑制する2021

    • Author(s)
      貝原 健太、中川 周士、井上 裕章、新井 祐志、藤井 雄太、鎌田 陽一郎、 松田 修、高橋 謙治
    • Organizer
      第36回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-21H03295
  • [Presentation] Influence of heat stress on SIRT1-transfected chondrocytes2021

    • Author(s)
      Kaihara K, Inoue H, Nakagawa S, Arai Y, Fujii Y, Mazda O, Takahashi K
    • Organizer
      2021 Annual Meeting of Orthopaedic Research Society(国際学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09507
  • [Presentation] Treadmill running suppressed joint destruction in a rheumatoid arthritis rat model2020

    • Author(s)
      Fujii Y, Inoue H, Arai Y, Shimomura S, Nakagawa S, Tsuchida S, Kamada Y, Kaihara K, Mazda O, Mikami Y
    • Organizer
      66th Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19620
  • [Presentation] Effect Of Hif-1α Stabilization By Deferoxamine On Chondrocyte And Articular Cartilage2020

    • Author(s)
      Kaihara Kenta、Nakagawa Shuji、Arai Yuji、Fujii Yuta、Inoue Hiroaki、Tsuchida Shinji、Kamada Yoichiro、Mazda Osam、Mikami Yasuo
    • Organizer
      66th Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05452
  • [Presentation] Effect of hif-1α stabilization by deferoxamine on chondrocyte and articular cartilage2020

    • Author(s)
      Kaihara K, Nakagawa S, Arai Y, Fujii Y, Inoue H, Tsuchida S, Kamada Y, Mazda O, Mikami Y
    • Organizer
      66th Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10752
  • [Presentation] Effect Of Hif-1α Stabilization By Deferoxamine On Chondrocyte And Articular Cartilage2020

    • Author(s)
      Kaihara Kenta、Nakagawa Shuji、Arai Yuji、Fujii Yuta、Inoue Hiroaki、Tsuchida Shinji、Kamada Yoichiro、Mazda Osam、Mikami Yasuo
    • Organizer
      66th Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H02136
  • [Presentation] 関節リウマチ症例への積極的なリハビリテーション治療の工夫2020

    • Author(s)
      遠山将吾,菱川法和,小田 良,沢田光思郎,徳永大作,高橋謙治,三上靖夫
    • Organizer
      第35回日本臨床リウマチ学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K11420
  • [Presentation] Treadmill Running Suppressed Joint Destruction In A Rheumatoid Arthritis Rat Model2020

    • Author(s)
      Yuta Fujii; Hiroaki Inoue; Yuji Arai; Seiji Shimomura; Shuji Nakagawa; Shinji Tsuchida; Yoichiro Kamada; Kenta Kaihara; Osam Mazda; Yasuo Mikami
    • Organizer
      2020 Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10752
  • [Presentation] トレッドミル走行がラット関節炎モデルの足関節に与える影響2020

    • Author(s)
      藤井雄太,井上裕章,中川周士,下村征史,新井祐志,松田 修,高橋謙治
    • Organizer
      第35回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-18K19620
  • [Presentation] Treadmill running suppressed joint destruction in a rheumatoid arthritis rat model2020

    • Author(s)
      Fujii Y, Inoue H, Arai Y, Shimomura S, Nakagawa S, Tsuchida S, Kamada Y, Kaihara K, Mazda O, Mikami Y
    • Organizer
      66th Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10752
  • [Presentation] 関節リウマチにおけるサルコペニア2020

    • Author(s)
      遠山将吾,菱川法和,小田 良,沢田光思郎,徳永大作,高橋謙治,三上靖夫
    • Organizer
      第48回日本関節病学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K11420
  • [Presentation] Analysis of reaction to tensile stress in chondrocytes in hypoxic environment2020

    • Author(s)
      Kamada Y, Inoue H, Arai Y, Shimomura S, Nakagawa S, Tsuchida S, Fujii Y, Kaihara K, Mazda O, Mikami Y
    • Organizer
      66th Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10752
  • [Presentation] Analysis Of Reaction To Tensile Stress In Chondrocytes In Hypoxic Environment2020

    • Author(s)
      Yoichiro Kamada; Hiroaki Inoue; Yuji Arai; Seiji Shimomura; Shuji Nakagawa; Shinji Tsuchida; Yuta Fujii; Kenta Kaihara; Osam Mazda; Yasuo Mikami
    • Organizer
      2020 Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19620
  • [Presentation] SIRT1導入細胞に対する温熱ストレスの検討2020

    • Author(s)
      貝原健太,井上裕章,中川周士,新井祐志,藤井雄太,松田 修,高橋謙治
    • Organizer
      第35回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-20K09507
  • [Presentation] Analysis Of Reaction To Tensile Stress In Chondrocytes In Hypoxic Environment2020

    • Author(s)
      Kamada Yoichiro、Inoue Hiroaki、Arai Yuji、Shimomura Seiji、Nakagawa Shuji、Tsuchida Shinji、Fujii Yuta、Kaihara Kenta、Mazda Osam、Mikami Yasuo
    • Organizer
      66th Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H02136
  • [Presentation] トレッドミル走行がラット関節炎モデルの足関節に与える組織学的影響2019

    • Author(s)
      藤井雄太,井上裕章,新井祐志,下村征史,中川周士,土田真嗣,鎌田陽一郎,貝原健太,松田 修,久保俊一
    • Organizer
      第34回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-18K10752
  • [Presentation] 新規関節リウマチ抗体薬開発のためのキメラ抗体作製2019

    • Author(s)
      山崎勤、新井祐志、中川周士、久保俊一、中西 徹
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-17K08379
  • [Presentation] Hypoxic Condition Promotes Differentiation From Human iPSC to Cartilage2019

    • Author(s)
      Shimomura S, Inoue H, Arai Y, Nakagawa S, Tsuchida S, Ichimaru S, Fujii Y, Mazda O, Kubo T
    • Organizer
      65th Annual Meeting of Orthopaedic Research Society
    • Data Source
      KAKENHI-PROJECT-17H02136
  • [Presentation] Efficacy of pristimerin for soft tissue sarcoma in vitro and in vivo study2019

    • Author(s)
      Daichi Hayashi, Toshiharu Shirai, Ryu Terauchi, Shinji Tsuchida, Naoki Mizoshiri, Yuki Mori, Yuji Arai, Osam Mazda, Toshikazu Kubo
    • Organizer
      ORS 2019 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10975
  • [Presentation] 低酸素環境下における伸展刺激に対する軟骨細胞のストレス応答解析2019

    • Author(s)
      鎌田陽一郎、井上裕章、新井祐志、下村征史、中川周士、土田真嗣、松田 修、久保俊一
    • Organizer
      日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-17H02136
  • [Presentation] Treadmill Running Ameliorates Articular Cartilage Destruction and Synovitis Histologically in a Rheumatoid Arthritis Rat Model2019

    • Author(s)
      Fujii Y, Inoue H, Arai Y, Shimomura S, Nakagawa S, Tsuchida S, Ichimaru S, Mazda O, Kubo T
    • Organizer
      65th Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10752
  • [Presentation] 関節リウマチにおけるキメラ抗体の作製2019

    • Author(s)
      山崎勤、中川周士、新井祐志、久保俊一、中西 徹
    • Organizer
      日本薬学会139年会
    • Data Source
      KAKENHI-PROJECT-17K08379
  • [Presentation] 新規関節リウマチ治療薬のターゲットCD81に対する抗体薬の開発2019

    • Author(s)
      山崎勤、中川周士、新井祐志、久保俊一、中西 徹
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K08379
  • [Presentation] 天然有機化合物であるプリスチメリンの骨肉腫細胞に対する抗腫瘍効果2018

    • Author(s)
      林 大智,白井寿治,寺内 竜,土田真嗣,溝尻直毅, 森 裕貴,勝山祐誠,新井祐志,松田 修,久保俊一
    • Organizer
      日本整形外科学会骨・軟部腫瘍学会
    • Data Source
      KAKENHI-PROJECT-17K10975
  • [Presentation] ヒトiPS細胞から軟骨組織分化における酸素濃度の影響の検討2018

    • Author(s)
      下村征史,井上裕章,新井祐志,中川周士,土田真嗣,市丸昌平,藤井雄太,松田 修,久保俊一
    • Organizer
      第33回日本整形外科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-18K19620
  • [Presentation] トレッドミル走行がラット関節炎モデルの膝関節に与える組織学的評価2018

    • Author(s)
      藤井雄太,井上裕章,新井祐志,中川周士,土田真嗣,下村征史,松田 修,久保俊一
    • Organizer
      第33回日本整形外科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-17H02136
  • [Presentation] Histological evaluation of treadmill running on knee joint of rat arthritis model2018

    • Author(s)
      Fujii Y, Inoue H, Arai Y, Nakagawa S, Tsuchida S, Shimomura S, Mazda O, Kubo T
    • Organizer
      26th Annual Meeting of European Orthopaedic Reserch Society
    • Data Source
      KAKENHI-PROJECT-17H02136
  • [Presentation] HIF-1α in articular cartilage is up-regulated by treadmill running in vivo2018

    • Author(s)
      Fujii Y, Inoue H, Arai Y, Nakagawa S, Tsuchida S, Shimomura S, Mazda O, Kubo T
    • Organizer
      21st World Congress of the Osteoarthritis Research Society International (OARSI)
    • Data Source
      KAKENHI-PROJECT-17H02136
  • [Presentation] The effects of treadmill exercise at a single time on knee articular cartilage in vivo2018

    • Author(s)
      Shimomura S, Inoue H, Arai Y, Nakagawa S, Tsuchida S, Ichimaru S, Fujii Y, Mazda O, Kubo T
    • Organizer
      26th Annual Meeting of European Orthopaedic Reserch Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19620
  • [Presentation] Effects of hypoxic conditions in differentiation of human iPSC to cartilage2018

    • Author(s)
      Seiji Shimomura, Hiroaki Inoue, Yuji Arai, Shuji Nakagawa, Shinji Tsuchida, Shohei Ichimaru, Yuta Fujii, Osamu Mazda, Toshikazu Kubo
    • Organizer
      2018 ORS annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05452
  • [Presentation] Effects of hypoxic conditions in differentiation of human iPSC to cartilage2018

    • Author(s)
      Seiji Shimomura, Hiroaki Inoue, Yuji Arai, Shuji Nakagawa, Shinji Tsuchida,Shohei Ichimaru, Yuta Fujii, Osamu Mazda, Toshikazu Kubo
    • Organizer
      64th Annual Meeting of Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H02136
  • [Presentation] 天然有機化合物であるプリスチメリンの線維肉腫細胞に対する抗腫瘍効果2018

    • Author(s)
      林 大智,白井寿治,寺内 竜,土田真嗣,溝尻直毅,森 裕貴,勝山祐誠,新井祐志,松田 修,久保俊一
    • Organizer
      日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-17K10975
  • [Presentation] The effect of treadmill running on knee articular cartilage in rats2017

    • Author(s)
      Seiji Shimomura, Hiroaki Inoue, Yuji Arai, Shuji Nakagawa, Shinji Tsuchida, Shohei Ichimaru, Osam Mazda, Toshikazu Kubo
    • Organizer
      20th World Congress of the Osteoarthritis Research Society International (OARSI)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462312
  • [Presentation] 低酸素環境によるヒトiPS細胞から軟骨組織への分化促進効果の検討2017

    • Author(s)
      下村征史,井上裕章,新井祐志,中川周士,土田真嗣,市丸昌平,松田 修,久保俊一
    • Organizer
      第32回日本整形外科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-16H05452
  • [Presentation] Regulation of inflammatory cytokine expression and osteoclastgenesis by gap junctional protein in vitro and in vivo.2017

    • Author(s)
      Seiji Shimomura, Shinji Tsuchida, Yuji Arai, Shuji Nakagawa, Hiroaki Inoue, Shohei Ichimaru, Yuta Fujii, Osam Mazda, Toshikazu Kubo
    • Organizer
      The 5th annual meeting of the international cytokine and interferon society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H02136
  • [Presentation] Regulation of inflammatory cytokine expression and osteoclastgenesis by gap junctional protein in vitro and in vivo.2017

    • Author(s)
      Seiji Shimomura, Shinji Tsuchida, Yuji Arai, Shuji Nakagawa, Hiroaki Inoue, Shohei Ichimaru, Yuta Fujii, Osam Mazda, Toshikazu Kubo
    • Organizer
      The 5th annual meeting of the international cytokine and interferon society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462312
  • [Presentation] The effect of treadmill running on knee articular cartilage in rats2017

    • Author(s)
      Seiji Shimomura, Hiroaki Inoue, Yuji Arai, Shuji Nakagawa, Shinji Tsuchida, Shohei Ichimaru, Osam Mazda, Toshikazu Kubo
    • Organizer
      20th World Congress of the Osteoarthritis Research Society International (OARSI)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15555
  • [Presentation] テトラスパニンCD81を標的とした新規次世代リウマチ治療薬の開発2017

    • Author(s)
      中西 徹、山崎 勤、新井祐志、中川周士、久保俊一
    • Organizer
      硬組織再生生物学会
    • Data Source
      KAKENHI-PROJECT-17K08379
  • [Presentation] The anti-tumor effect of chemotherapy on human osteosarcoma cell line in combination with suppression of heat shock protein2017

    • Author(s)
      Mori Y, Terauchi R, Shirai T, Tsuchida S, Mizoshiri N, Arai Y, Mazda O, Kubo T
    • Organizer
      ORS 2017 Annual Meeting
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2017-03-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462273
  • [Presentation] The effect of treadmill running on knee articular cartilage in rats2017

    • Author(s)
      Seiji Shimomura, Hiroaki Inoue, Yuji Arai, Shuji Nakagawa, Shinji Tsuchida, Shohei Ichimaru, Osam Mazda, Toshikazu Kubo
    • Organizer
      20th World Congress of the Osteoarthritis Research Society International (OARSI)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H02136
  • [Presentation] 天然有機化合物であるプリスチメリンの骨肉腫細胞株に対する抗腫瘍効果の検討2017

    • Author(s)
      森 裕貴,白井寿治,寺内 竜,土田真嗣,溝尻直毅,新井祐志,松田 修,久保俊一
    • Organizer
      第32回 日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-17K10975
  • [Presentation] トレッドミル走行がラット膝関節軟骨に与える影響2016

    • Author(s)
      下村征史,井上裕章,新井祐志,中川周士,土田真嗣,市丸昌平,松田 修,久保俊一
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-26462312
  • [Presentation] Pharmacological effects of exogenous hyaluronic acid in articular cartilage under hypoxia2016

    • Author(s)
      Ichimaru S, Nakagawa S, Arai Y, Tsuchida S, Inoue H, Shimomura S, Mazda O, Kubo T
    • Organizer
      第29回日本軟骨代謝学会
    • Place of Presentation
      広島
    • Year and Date
      2016-02-19
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] The anti-tumor effect of chemotherapy on human osteosarcoma cell line in combination with suppression of heat shock protein2016

    • Author(s)
      Mori Y, Terauchi R, Shirai T, Tsuchida S, Mizoshiri N, Arai Y, Mazda O, Kubo T
    • Organizer
      EUROPEAN ORTHOPAEDIC RESEARCH SOCIETY 24th ANNUAL MEETING
    • Place of Presentation
      Bologna,Italy
    • Year and Date
      2016-09-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462273
  • [Presentation] Pharmacological effects of exogenous hyaluronan in articular cartilage under hypoxia2016

    • Author(s)
      Ichimaru S, Nakagawa S, Arai Y, Tsuchida S, Inoue H, Shimomura S, Mazda O, Kubo T
    • Organizer
      19th World Congress of the Osteoarthritis Research Society International (OARSI)
    • Place of Presentation
      Amsterdam, Netherlands
    • Year and Date
      2016-04-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15555
  • [Presentation] 低酸素環境下における外因性ヒアルロン酸の薬理効果の変化2016

    • Author(s)
      市丸昌平,中川周士,新井祐志,土田真嗣,井上裕章,下村征史,松田 修,久保俊一
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K15555
  • [Presentation] 骨肉腫細胞株に対する化学療法と熱タンパク抑制法を併用した抗腫瘍効果の検討2016

    • Author(s)
      森 裕貴,寺内 竜,白井寿治,土田真嗣,溝尻直毅,新井祐志,松田 修,久保俊一
    • Organizer
      第31回日本整形外科学会 基礎学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-26462273
  • [Presentation] トレッドミル走行がラット膝関節軟骨に与える影響2016

    • Author(s)
      下村征史,井上裕章,新井祐志,中川周士,土田真嗣,市丸昌平,松田 修,久保俊一
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K15555
  • [Presentation] 骨肉腫細胞株に対する化学療法と熱タンパク抑制法を併用した抗腫瘍効果の検討2016

    • Author(s)
      森 裕貴,寺内 竜,白井寿治,土田真嗣,溝尻直毅,新井祐志,松田 修,久保俊一
    • Organizer
      第31回日本整形外科学会 基礎学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K10454
  • [Presentation] 骨肉腫細胞株に対する化学療法と熱タンパク抑制法を併用した抗腫瘍効果の検討2016

    • Author(s)
      森 裕貴,寺内 竜,白井寿治,土田真嗣,溝尻直毅,新井祐志,松田 修,久保俊一
    • Organizer
      第49回日本整形外科学会 骨・軟部腫瘍学術集会
    • Place of Presentation
      東京
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-26462273
  • [Presentation] Pharmacological effects of exogenous hyaluronic acid in articular cartilage under hypoxia2016

    • Author(s)
      Ichimaru S, Nakagawa S, Arai Y, Tsuchida S, Inoue H, Shimomura S, Mazda O, Kubo T
    • Organizer
      第29回日本軟骨代謝学会
    • Place of Presentation
      広島
    • Year and Date
      2016-02-19
    • Data Source
      KAKENHI-PROJECT-15K15555
  • [Presentation] 低酸素環境下における外因性ヒアルロン酸の薬理効果の変化2016

    • Author(s)
      市丸昌平,中川周士,新井祐志,土田真嗣,井上裕章,下村征史,松田 修,久保俊一
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-26462312
  • [Presentation] Pharmacological effects of exogenous hyaluronic acid in articular cartilage under hypoxia2016

    • Author(s)
      Ichimaru S, Nakagawa S, Arai Y, Tsuchida S, Inoue H, Shimomura S, Mazda O, Kubo T
    • Organizer
      第29回日本軟骨代謝学会
    • Place of Presentation
      広島
    • Year and Date
      2016-02-19
    • Data Source
      KAKENHI-PROJECT-26462312
  • [Presentation] Pharmacological effects of exogenous hyaluronan in articular cartilage under hypoxia2016

    • Author(s)
      Ichimaru S, Nakagawa S, Arai Y, Tsuchida S, Inoue H, Shimomura S, Mazda O, Kubo T
    • Organizer
      19th World Congress of the Osteoarthritis Research Society International (OARSI)
    • Place of Presentation
      Amsterdam, Netherlands
    • Year and Date
      2016-04-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462312
  • [Presentation] 低酸素環境下にある軟骨細胞に対する外因性ヒアルロン酸の薬理効果2015

    • Author(s)
      市丸昌平,中川周士,新井祐志,土田真嗣,井上裕章,本城邦晃,白井寿治,寺内 竜,松田 修,久保俊一
    • Organizer
      第30回日本整形外科学会基礎学術集会
    • Place of Presentation
      富山
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-26462312
  • [Presentation] HSP70 induced by HIF-1α regulates anabolic responses in chondrocytes under hypoxic conditions2015

    • Author(s)
      Honjo K, Arai Y, Tsuchida S, Nakagawa S, Inoue H, Saito M, Ichimaru S, Shimomura S, Inoue A, Terauchi R, Mazda O, Kubo T
    • Organizer
      18th World Congress of the Osteoarthritis Research Society International (OARSI)
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2015-04-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] 低酸素環境下にある軟骨細胞に対する外因性ヒアルロン酸の薬理効果2015

    • Author(s)
      市丸昌平,中川周士,新井祐志,土田真嗣,井上裕章,本城邦晃,白井寿治,寺内 竜,松田 修,久保俊一
    • Organizer
      第30回日本整形外科学会基礎学術集会
    • Place of Presentation
      富山
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] HSP70 induced by HIF-1α regulates anabolic responses in chondrocytes under hypoxic conditions.2015

    • Author(s)
      Honjo K, Arai Y, Tsuchida S, Nakagawa S, Inoue H, Saito M, Ichimaru S, Shimomura S, Inoue A, Terauchi R, Mazda O, Kubo T
    • Organizer
      18th World Congress of the Osteoarthritis Research Society International (OARSI)
    • Place of Presentation
      Seattle, U.S.A
    • Year and Date
      2015-04-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15555
  • [Presentation] 低酸素環境下にある軟骨細胞に対する外因性ヒアルロン酸の薬理効果2015

    • Author(s)
      市丸昌平,中川周士,新井祐志,土田真嗣,井上裕章,本城邦晃,白井寿治,寺内 竜,松田 修,久保俊一
    • Organizer
      第30回日本整形外科学会基礎学術集会
    • Place of Presentation
      富山
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-15K15555
  • [Presentation] The expression levels of connexin 43 in human synovium of rheumatoid arthritis2014

    • Author(s)
      Tomohiro Matsuki, Yuji Arai, Shinji Tsuchida, Ryu Terauchi, Hiroaki Inoue, Shuji Nakagawa, Atsuo Inoue, Kuniaki Honjo, Toru Morihara, Toshiharu Shirai, Osam Mazda, Toshikazu Kubo
    • Organizer
      Orthopaedic Research Society
    • Place of Presentation
      New Orleans
    • Data Source
      KAKENHI-PROJECT-24659683
  • [Presentation] Sonoporation-mediated transduction of siena targeting TNF alpha ameliorated experimental arthritis2014

    • Author(s)
      Inoue H, Arai Y, Terauchi R, Nakagawa S, Saito M, Tsuchida S, Inoue A, Matsuki T, Morihara T, Shirai T, Mazda O, Kubo T
    • Organizer
      Orthopaedic Research Society
    • Place of Presentation
      New Orleans
    • Data Source
      KAKENHI-PROJECT-24659683
  • [Presentation] Anti-inflammatory effects of lansoprazole by suppressing ROS production in murine macrophage RAW 264.7 cells2014

    • Author(s)
      S. Ichimaru, S. Nakagawa, Y. Arai, S. Tsuchida, H. Inoue, T. Matsuki, Y. Mikami, T. Ikeda, R. Oda, O. Mazda, T. Kubo
    • Organizer
      2014 Orthopaedic Research Society Annual Meeting
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Year and Date
      2014-03-16
    • Data Source
      KAKENHI-PROJECT-23591318
  • [Presentation] Anti-inflammatory effects of lansoprazole by suppressing ROS production in murine macrophage RAW 264.7 cells2014

    • Author(s)
      S. Ichimaru, S. Nakagawa, Y. Arai, S. Tsuchida, H. Inoue, T. Matsuki, Y. Mikami, T. Ikeda, R. Oda, O. Mazda, T. Kubo
    • Organizer
      2014 Orthopaedic Research Society Annual Meeting
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Year and Date
      2014-03-16
    • Data Source
      KAKENHI-PROJECT-25670656
  • [Presentation] Anti-inflammatory effects of lansoprazole by suppressing ROS production in murine macrophage RAW 264.7 cells2014

    • Author(s)
      Shohei Ichimaru, Shuji Nakagawa, Yuji Arai, Shinji Tsuchida, Hiroaki Inoue, Tomohiro Matsuki, Yasuo Mikami, Takumi Ikeda, Ryo Oda, Osam Mazda, Toshikazu Kubo
    • Organizer
      Orthopaedic Research Society
    • Place of Presentation
      New Orleans
    • Data Source
      KAKENHI-PROJECT-24659683
  • [Presentation] Sonoporation-mediated transduction of siRNA targeting TNF alpha ameliorated experimental arthritis2014

    • Author(s)
      Inoue H, Arai Y, Nakagawa S, Saito M ,Tsuchida S, Inoue A, Matsuki T, Morihara T, Shirai T, Mazda, O, Kubo T
    • Organizer
      60th Annual Meeting of OrthopaedicResearch Society
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Data Source
      KAKENHI-PROJECT-25670656
  • [Presentation] Sonoporation-mediated transduction of siRNA targeting TNF alpha ameliorated experimental arthritis2014

    • Author(s)
      Inoue H, Arai Y, Nakagawa S, Saito M ,Tsuchida S, Inoue A, Matsuki T, Morihara T, Shirai T, Mazda, O, Kubo T
    • Organizer
      60th Annual Meeting of Orthopaedic Research Society
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Data Source
      KAKENHI-PROJECT-23591318
  • [Presentation] テトラスパニンCD81を標的とする新規リウマチ治療薬の開発2014

    • Author(s)
      中川周士、新井祐志、森宏樹、松下有美、久保俊一、中西徹
    • Organizer
      日本薬学会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-27
    • Data Source
      KAKENHI-PROJECT-23590102
  • [Presentation] The roles of heat shock protein 70 on chondrocyte2013

    • Author(s)
      Matsuki T, Arai Y, Tsuchida S, Terauchi R, Inoue H, Nakagawa S, Inoue A, Mazda O, Kubo T
    • Organizer
      16th World Congress of the Osteoarthritis Research Society International
    • Place of Presentation
      Philadelphia, USA.
    • Year and Date
      2013-04-18
    • Data Source
      KAKENHI-PROJECT-25670656
  • [Presentation] The roles of heat shock protein 70 on chondrocyte2013

    • Author(s)
      Matsuki T, Arai Y, Tsuchida S, Terauchi R, Inoue H, Nakagawa S, Inoue A, Mazda O, Kubo T.
    • Organizer
      16th World Congress of the Osteoarthritis Research Society International
    • Place of Presentation
      Philadelphia, U.S.A
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] The roles of heat shock protein 70 on chondrocyte2013

    • Author(s)
      Matsuki T, Arai Y, Tsuchida S, Terauchi R, Inoue H, Nakagawa S, Inoue A, Mazda O, Kubo T
    • Organizer
      16th World Congress of the Osteoarthritis Research Society International (OARSI)
    • Place of Presentation
      Philadelphia, U.S.A
    • Year and Date
      2013-04-18
    • Data Source
      KAKENHI-PROJECT-24659683
  • [Presentation] 関節リウマチ滑膜におけるconnexin43の発現2013

    • Author(s)
      松木智宏、新井祐志、土田真嗣、本城邦晃、中川周士、井上裕章、寺内竜、松田修、久保俊一
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-24659683
  • [Presentation] Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes2013

    • Author(s)
      Inoue H, Arai Y, Terauchi R, Nakagawa S, Saito M, Hiraoka N, Tsuchida S, Matsuki T, Mazda O, Kubo T
    • Organizer
      16th World Congress of the Osteoarthritis Research Society International (OARSI)
    • Place of Presentation
      Philadelphia, U.S.A
    • Year and Date
      2013-04-18
    • Data Source
      KAKENHI-PROJECT-24659683
  • [Presentation] Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes2013

    • Author(s)
      Inoue H, Arai Y, Terauchi R, Nakagawa S, Saito M, Hiraoka N, Tsuchida S, Matsuki T, Mazda Osam, Kubo T
    • Organizer
      16th World Congress of the Osteoarthritis Research Society International
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-23591318
  • [Presentation] 低酸素環境下の軟骨細胞におけるheat shock protein 70の役割2013

    • Author(s)
      土田真嗣,新井祐志,寺内 竜,中川周士,井上敦夫,平岡延之,井上裕章,齊藤正純,松木智宏,久保俊一
    • Organizer
      第26回日本軟骨代謝学会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2013-03-02
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] ソノポレーションで導入したTNF-α特異的siRNAによる関節炎モデルの治療効果2013

    • Author(s)
      井上裕章,新井祐志,中川周士,寺内竜,土田真嗣,松木智宏,井上敦夫,齊藤正純,松田修,久保俊一
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      千葉県
    • Year and Date
      2013-10-18
    • Data Source
      KAKENHI-PROJECT-24659683
  • [Presentation] Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes2013

    • Author(s)
      Inoue H, Arai Y, Terauchi R, Nakagawa S, Saito M, Hiraoka N, Tsuchida S, Matsuki T, Mazda O, Kubo T.
    • Organizer
      16th World Congress of the Osteoarthritis Research Society International
    • Place of Presentation
      Philadelphia, U.S.A
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes2013

    • Author(s)
      Inoue H, Arai Y, Terauchi R, Nakagawa S, Saito M, Hiraoka N, Tsuchida S, Matsuki T, Mazda Osam, Kubo T
    • Organizer
      16th World Congress of the Osteoarthritis Research Society International
    • Place of Presentation
      Philadelphia, USA.
    • Data Source
      KAKENHI-PROJECT-25670656
  • [Presentation] 活性化マクロファージに対するROSを介したランソプラゾールの抗炎症効果の解析2013

    • Author(s)
      市丸昌平,中川周士,新井祐志,土田真嗣,井上裕章,松木智宏,久保俊一
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      千葉県
    • Year and Date
      2013-10-17
    • Data Source
      KAKENHI-PROJECT-24659683
  • [Presentation] 変形性関節症の最新療法2013

    • Author(s)
      新井祐志
    • Organizer
      第40回日本生体電気・物理刺激研究会
    • Place of Presentation
      ウェスティン都ホテル京都
    • Data Source
      KAKENHI-PROJECT-24659683
  • [Presentation] 温熱刺激とグルタミンを併用したHSP70誘導法による変形性関節症に対する進行抑制効果の検討2013

    • Author(s)
      松木智宏,新井祐志,藤田伸弥,井上裕章,中川周士,土田真嗣,寺内 竜,井上敦夫,齊藤正純,松田 修,久保俊一
    • Organizer
      第40回日本生体電気・物理刺激研究会
    • Place of Presentation
      ウェスティン都ホテル京都
    • Data Source
      KAKENHI-PROJECT-23650333
  • [Presentation] The roles of heat shock protein 70 on chondrocyte2013

    • Author(s)
      Matsuki T, Arai Y, Tsuchida S, Terauchi R, Inoue H, Nakagawa S, Inoue A, Mazda O, Kubo T
    • Organizer
      16th World Congress of the Osteoarthritis Research Society International
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-23591318
  • [Presentation] 活性化マクロファージに対するランソプラゾールの抗炎症効果の解析2013

    • Author(s)
      中川周士,新井祐志,井上裕章,土田真嗣,小田 良,徳永大作,川人 豊,妹尾高宏,久保俊一
    • Organizer
      第57回日本リウマチ学会総会・学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] Silencing the Expression of Connexin 43 Decreases Inflammation in Rat Synovium2012

    • Author(s)
      Tsuchida S, Arai Y, Terauchi R, Honjo K, Nakagawa S, Inoue H, Oda R, Tokunaga D, Mazda O, Kubo T
    • Organizer
      58th Annual Meeting of Orthopaedic Research Society
    • Place of Presentation
      Moscone West Convention Center(San Francisco, California)
    • Data Source
      KAKENHI-PROJECT-23659731
  • [Presentation] 低酸素環境下の軟骨細胞におけるheat shock protein 70の役割2012

    • Author(s)
      土田真嗣,新井祐志,寺内 竜,井上裕章,齊藤正純,平岡延之,松田修,久保俊一
    • Organizer
      第27回日本整形外科学会基礎学術集会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2012-10-26
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] Regulation of osteoclastogenesis by connexin 43 in vitro and in vivo2012

    • Author(s)
      土田真嗣,新井祐志,寺内 竜,本城邦晃,井上裕章,小田 良,徳永大作,久保俊一
    • Organizer
      第56回日本リウマチ学会総会・学術集会
    • Place of Presentation
      京都
    • Year and Date
      2012-04-25
    • Data Source
      KAKENHI-PROJECT-23659731
  • [Presentation] グルタミン投与と温熱刺激の併用による軟骨細胞へのHSP70発現誘導2012

    • Author(s)
      井上裕章、新井祐志、藤田伸弥、中川周士、寺内竜、土田真嗣、齊藤正純、久保俊一
    • Organizer
      第25回 日本軟骨代謝学会
    • Place of Presentation
      ウィル愛知(愛知県)
    • Data Source
      KAKENHI-PROJECT-23650333
  • [Presentation] 温熱刺激とグルタミンの併用によるHSP70誘導療法のラット変形性関節症に対する進行抑制効果2012

    • Author(s)
      井上裕章,新井祐志,藤田伸弥,中川周士,土田真嗣,寺内 竜,井上敦夫,齊藤正純,松田 修,久保俊一
    • Organizer
      第27回日本整形外科学会基礎学術集会
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-23650333
  • [Presentation] 低酸素環境がHSP70と軟骨細胞外基質合成に与える影響2011

    • Author(s)
      土田真嗣, 新井祐志, 寺内竜, 本城邦晃, 中川周士, 平岡延之, 井上裕章, 齊藤正純, 久保俊一
    • Organizer
      第24回日本軟骨代謝学会
    • Place of Presentation
      九州大学医学部百年講堂(福岡県)
    • Year and Date
      2011-03-05
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Presentation] Effect of hypoxia on cartilage matrix gene and heat shock protein 70 expression in cultured chondrocytes2011

    • Author(s)
      Shinji Tsuchida, Yuji Arai, Ryu Terauchi, Kuniaki Honjo, Shuji Nakagawa, Nobuyuki Hiraoka, Hiroaki Inoue, Masazumi Saito, Osam Mazda, Tsunao Kishida, Toshikazu Kubo
    • Organizer
      57th Annual Meeting of Orthopaedic Research Society
    • Place of Presentation
      Long Beach Convention Center(Long Beach, CA, USA)
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Presentation] The effect of connexin43 for pro-inflammatory cytokines in rat FLSs2011

    • Author(s)
      土田真嗣,新井祐志,寺内 竜,本城邦晃,中川周士,井上裕章,小田 良,徳永大作,久保俊一
    • Organizer
      第55回日本リウマチ学会総会・学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-23659731
  • [Presentation] Effect of hypoxia on the expression of cartilage matrix gene and heat shock protein 70 in cultured chondrocytes2011

    • Author(s)
      Tsuchida S, Arai Y, Terauchi R, Honjo K, Inoue H, Saito M, Mazda O, Kubo T
    • Organizer
      14th World Congress of the Osteoarthritis Research Society International (OARSI)
    • Place of Presentation
      Hilton San Diego Bayfront (San Diego, CA)
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Presentation] Effect of hypoxia on the expression of cartilage matrix gene and heat shock protein 70 in cultured chondrocytes2011

    • Author(s)
      Shinji Tsuchida, Yuji Arai, Ryu Terauchi, Kuniaki Honjo, Hiroaki Inoue, Masazumi Saito, Osam Mazda, Toshikazu Kubo
    • Organizer
      14th World Congress of the Osteoarthritis Research Society International(OARSI)
    • Place of Presentation
      Hilton San Diego Bayfront(San Diego, CA, USA)
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Presentation] Effect of hypoxia on cartilage matrix gene and heat shock protein 70 expression in cultured chondrocytes2011

    • Author(s)
      Tsuchida S, Arai Y, Terauchi R, Honjo K, Nakagawa S, Hiraoka N, Inoue H, Saito M, Mazda O, Kishida T, Kubo T
    • Organizer
      57th Annual Meeting of Orthopaedic Research Society
    • Place of Presentation
      Long Beach Convention Center (Long Beach, CA)
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Presentation] 低酸素環境およびHIF-1αが培養軟骨におけるHSP70と軟骨細胞外基質合成に与える影響2011

    • Author(s)
      土田真嗣, 新井祐志, 寺内竜, 本城邦晃, 中川周士, 平岡延之, 井上裕章, 齊藤正純, 松田修, 久保俊一
    • Organizer
      第26回日本整形外科学会基礎学術集会
    • Place of Presentation
      ベイシア文化ホール(群馬県)
    • Year and Date
      2011-10-21
    • Data Source
      KAKENHI-PROJECT-20390404
  • [Presentation] 関節軟骨の分子生物学的研究―ストレス応答を中心に―

    • Author(s)
      新井祐志
    • Organizer
      第27回日本軟骨代謝学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] ソノポレーションで導入したTNF-α特異的siRNAによる関節炎モデルの治療効果

    • Author(s)
      井上裕章,新井祐志,中川周士,寺内 竜,土田真嗣,松木智宏,井上敦夫,齊藤正純,松田 修,久保俊一
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] Effect of inflammation stress on the hypertrophic differentiation-related gene expression in cultured chondrocytes

    • Author(s)
      Inoue Hiroaki, Arai Yuji, Terauchi Ryu, Nakagawa Shuji, Saito Masazumi, Tsuchida Shinji, Matsuki Tomohiro, Ichimaru Shohei, Mazda Osam,Kubo Toshikazu
    • Organizer
      2015 OARSI World Congress
    • Place of Presentation
      Paris, France
    • Year and Date
      2014-04-24 – 2014-04-27
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] 活性化マクロファージに対するROSを介したランソプラゾールの抗炎症効果の解析

    • Author(s)
      市丸昌平,中川周士,新井祐志,土田真嗣,井上裕章,松木智宏,久保俊一
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] The anabolic effects of HIF-1α-induced HSP70 in rabbit articular chondrocyte under hypoxic conditions

    • Author(s)
      Shohei Ichimaru, Shinji Tsuchida, Yuji Arai, Shuji Nakagawa, Hiroaki Inoue, Tomohiro Matsuki, Kuniaki Honjo, Keiichiro Ueshima, Osam Mazda, Toshikazu Kubo
    • Organizer
      Orthopaedic Research Society 2015 annual meeting
    • Place of Presentation
      Las Vegas
    • Year and Date
      2015-03-28 – 2015-03-31
    • Data Source
      KAKENHI-PROJECT-26462312
  • [Presentation] テトラスパニンCD81を標的とする新規リウマチ治療薬の開発

    • Author(s)
      中川周士、新井祐志、森 宏樹、松下有美、久保俊一、中西 徹
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PROJECT-23590102
  • [Presentation] トレッドミル走行がラット膝関節軟骨に与える影響

    • Author(s)
      松木智宏,新井祐志,中川周士,土田真嗣,井上裕章,寺内 竜,井上敦夫,久保俊一
    • Organizer
      第27回日本軟骨代謝学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24390356
  • [Presentation] 活性化マクロファージに対する一酸化窒素の産生抑制によるランソプラゾールの抗炎症効果の解析

    • Author(s)
      市丸昌平,中川周士,新井祐志,土田真嗣,井上裕章,松木智宏,谷口大吾,小田 良,藤原浩芳,久保俊一
    • Organizer
      第27回日本軟骨代謝学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24390356
  • 1.  NAKAGAWA Shuji (30643382)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 56 results
  • 2.  KUBO Toshikazu (20178031)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 71 results
  • 3.  Mazda Osam (00271164)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 39 results
  • 4.  NAKANISHI Tohru (30243463)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 14 results
  • 5.  KISHIDA Tsunao (00370205)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 12 results
  • 6.  TERAUCHI Ryu (20575154)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 31 results
  • 7.  NAGATSUKA Hitoshi (70237535)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  井上 裕章 (60457968)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 26 results
  • 9.  Shirai Toshiharu (20397186)
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  • 10.  高橋 謙治 (30347447)
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    # of Collaborated Products: 0 results
  • 11.  WATANABE Masahiko (00182949)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  山崎 勤 (80596148)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 13.  遠山 将吾 (00388183)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 14.  山本 健太 (00636160)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  TAMURA Yutaka (50263174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  Fujiwara Hiroyoshi (90381962)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 17.  YAGITA Kazuhiro (90324920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  MORIHARA Toru (90336735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  KITABATAKE Yasuji (80506494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  OHGITANI Eriko (80300820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  WATANABE Eri (20433253)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SHIN-YA Masaharu (10405277)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  森 宏樹 (40388989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 24.  中島 利博 (90260752)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  浅沼 幹人 (00273970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  山川 直樹 (20583040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  土田 真嗣 (10719834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 28.  清水 一憲 (70402500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  徳永 大作 (90343409)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 30.  菱川 法和 (10943780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 31.  沢田 光思郎 (40460555)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 32.  大橋 鈴世 (50440889)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  三上 靖夫 (80360030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 34.  相良 亜木子 (10767916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  NISHIOKA Keisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  SOWA Yoshihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  SAKAI Ryo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  甲斐 広文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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