Arai Yuji 新井祐志

… Alternative Names

Researcher Number	50347449
Other IDs
Affiliation (Current)	2021: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help	2016 – 2021: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2012 – 2016: 京都府立医科大学, 医学研究科, 講師 2011 – 2015: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2013: 京都府立医科大学, 医学研究科, 教授 2013: 京都府立医科大学, 医学部, 講師 … More
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Rehabilitation science/Welfare engineering / Basic Section 59010:Rehabilitation science-related Except Principal Investigator Orthopaedic surgery / Basic Section 59010:Rehabilitation science-related / Biological pharmacy / Drug development chemistry / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56020:Orthopedics-related / Metabolomics / Rehabilitation science/Welfare engineering / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 変形性関節症 / HIF-1α / 軟骨 / 低酸素 / 低酸素環境 / 整形外科 / リハビリテーション / small interfering RNA / 関節滑膜 / ADAMTS-5 … More Except Principal Investigator 関節リウマチ / CD81 / 変形性関節症 / テトラスパニン / 低酸素 / 軟骨 / 再生医療 / 骨肉腫 / 整形外科学 / シノビオリン / heat shock protein 70 / HSP70 / 炎症性サイトカイン / アポトーシス / iPS細胞 / 骨軟骨代謝学 / 骨芽細胞 / サルコペニア / 滑膜細胞 / ストレス応答機構 / グルタミン / siRNA / モノクローナル抗体 / 温熱療法 / 関節軟骨 / 軟骨細胞 / メカニカルストレス / 軟骨代謝 / 再生医学 / 遺伝子治療 / ヒアルロン酸 / ダイレクト・コンヴァージョン / フレイル / リハビリテーション / リウマチ / DNAチップ / 温熱 / マイクロウェーブ / 関節疾患 / 低酸素誘導因子 / 骨形成因子 / サンドイッチELISA / TNFalpha / グリア細胞 / ELISA / 糖脂質代謝 / ﾒﾀﾎﾞﾘｯｸｼﾝﾄﾞﾛｰム / 褐色脂肪細胞 / メタボリックシンドローム / ダイレクトコンヴァージョン / ﾒﾀﾎﾞﾘｯｸｼﾝﾄﾞﾛｰﾑ / 微弱電流刺激 / ユビキチン化タンパク / リウマチ病学 / コネキシン43 / ギャップ結合 / 破骨細胞 / 滑膜炎 / コネキシン / ストレス応答 / 概日リズム / リプログラミング / 炎症生サイトカイン / 化学療法 / シスプラチン / Hsp70 / Ｈｓp70 / SiRNA / 温熱刺激 / 分子標的治療薬 / 骨肉腫制御 / 分子標的治療 / テトラスパニンファミリー / HIF-1α / 幹細胞 / 物理刺激 / 軟骨分化 / 硝子軟骨 / 骨粗鬆症 / 骨・軟骨代謝学 / キメラ抗体 / 遺伝子クローニング / 間接リウマチ / プリスチメリン / 細胞増殖抑制効果 / テルペノイド / 天然有機化合物 / カスパーゼ / 天然化合物 / 運動療法 / カチオン化 / エクソソーム / バイオマイクロシステム / 老化 / 骨格筋細胞 / 身体活動量 / 高齢者 / 健康づくりのための身体活動基準 / 定量化 / 筋肉量 / ダイレクト・リプログラミング / 整形外科 / 電気刺激 / HYBID Less

Establishment of a new exercise therapy for osteoarthritis using HIF-1alpha regulation by hypoxiaPrincipal Investigator
- Principal Investigator
  
  新井祐志
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of the next generation OA hyperthermia using a novel photothermal DDS
- Principal Investigator
  
  高橋謙治
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Prevention of Skeletal Muscle Fibrosis by a Novel Electrical Stimulation Method - Development of an Effective Treatment for Secondary Sarcopenia-
- Principal Investigator
  
  遠山将吾
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of low-load exercise therapy using molecular biological techniques for rheumatoid arthritis with sarcopenia
- Principal Investigator
  
  中川周士
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of anti-tumor drugs targeting CD81
- Principal Investigator
  
  中西徹
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Shujitsu University
低酸素環境での新規分子HYBIDの制御による変形性関節症治療法の開拓
- Principal Investigator
  
  井上裕章
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kyoto Prefectural University of Medicine
筋老化の分子機構解明の為の３D培養骨格筋組織の開発
- Principal Investigator
  
  岸田綱郎
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kyoto Prefectural University of Medicine
リハビリテーションの質を可視化するー健康長寿に向けた負荷量見える化の試みー
- Principal Investigator
  
  徳永大作
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kyoto Prefectural University of Medicine
Regeneration of bone and cartilage tissues by means of chemical direct reprogramming
- Principal Investigator
  
  Osam Mazda
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
低酸素誘導因子の制御による関節リウマチの運動療法の開発-サルコペニアの克服-
- Principal Investigator
  
  中川周士
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of charge based DDS for OA based on the negative charge of aggrecan
- Principal Investigator
  
  Kubo Toshikazu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Development of novel gene therapy for rheumatoid arthritis
- Principal Investigator
  
  Nakanishi Tohru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Shujitsu University
Development of a novel therapeutic drug for osteosarcoma using pristimerin
- Principal Investigator
  
  Terauchi Ryu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Development of HIF-1a-induced exercise therapy focusing on the intra-articular hypoxic environmentPrincipal Investigator
- Principal Investigator
  
  Arai Yuji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kyoto Prefectural University of Medicine
Development of a new method for regenerating hyaline cartilage using a bioreactor for iPS cells
- Principal Investigator
  
  Kubo Toshikazu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Development of novel anti-cancer drug targeting CD81 of osteosarcoma
- Principal Investigator
  
  Shirai Toshiharu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Development of new OA therapy targeting HIF-1a
- Principal Investigator
  
  Kubo Toshikazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Development of novel therapeutic compounds for rheumatoid arthritis targeting CD81
- Principal Investigator
  
  Nakanishi Tohru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Shujitsu University
Development of stump treatment method using heat shock protein inhibition technique for sarcoma
- Principal Investigator
  
  Terauchi Ryu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Investigation of stress response mechanism of chondrocytes by reproduction of physiological hypoxic environmentPrincipal Investigator
- Principal Investigator
  
  Arai Yuji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Pathogenesis and regenerative therapy of osteoporosis
- Principal Investigator
  
  Mazda Osam
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
crosstalk between stress response and the circadian rhythm in cartilage
- Principal Investigator
  
  KUBO TOSHIKAZU
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Bone regeneration based on direct reprogramming technologies
- Principal Investigator
  
  MAZDA Osam
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
New development of the molecular targeted therapy for osteoarthritis arthritis with respect to stress-response mechanism
- Principal Investigator
  
  Kubo Toshikazu
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Reclamation of a novel OA therapy by the control of MyostatinPrincipal Investigator
- Principal Investigator
  
  ARAI Yuji
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Development of novel antibody therapy targeting tetraspanin CD81
- Principal Investigator
  
  NAKANISHI Tohru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Shujitsu University
Toward novel molecular targeting strategies for the metabolic syndrome
- Principal Investigator
  
  KISHIDA Tsunao
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto Prefectural University of Medicine
The analysis of thermotherapy combined with drugs for osteoarthritis
- Principal Investigator
  
  KUBO Toshikazu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kyoto Prefectural University of Medicine
Possibility of connexin43 as a new therapeutic target for rheumatoid arthritis
- Principal Investigator
  
  TERAUCHI Ryu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
The analysis of cellular stress response towards novel conservative therapies for joint disease
- Principal Investigator
  
  KUBO Toshikazu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Isolation and identification of CD81 as a novel target for treatment of rheumatoid arthritis.
- Principal Investigator
  
  NAKANISHI Tohru
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Shujitsu University
関節軟骨へのsiRNA導入法の確立-変形性関節症の新しい保存療法の開発へ向けて-Principal Investigator
- Principal Investigator
  
  新井祐志
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
変形性関節症および軟骨損傷に対する線維芽細胞を用いた遺伝子治療の開発Principal Investigator
- Principal Investigator
  
  新井祐志
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine

[Book] 別冊BIO Clinica　慢性炎症と疾患2016
- Author(s)
  中西　徹、山崎　勤、新井祐志、中川周士、久保俊一
- Total Pages
  168
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-26460165
[Book] 生体電気・物理刺激による骨・軟部組織修復法(温熱刺激による変形性関節症の進行抑制効果)2012
- Author(s)
  新井祐志,土田真嗣,藤田伸弥
- Total Pages
  304
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-24390356
[Journal Article] Direct conversion of human fibroblasts into adipocytes using a novel small molecular compound: implications for regenerative therapy for adipose tissue defects2021
- Author(s)
  Yoshihiro Sowa *, Tsunao Kishida, Fiona Louis, Seiji Sawai, Seki Makoto, Kenji Takahashi, Toshiaki Numajiri, Osam Mazda
- Journal Title
  
  Cells
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22690
[Journal Article] Treadmill Running in Established Phase Arthritis Inhibits Joint Destruction in Rat Rheumatoid Arthritis Models2020
- Author(s)
  Fujii Yuta、Inoue Hiroaki、Arai Yuji、Shimomura Seiji、Nakagawa Shuji、Kishida Tsunao、Tsuchida Shinji、Kamada Yoichiro、Kaihara Kenta、Shirai Toshiharu、Terauchi Ryu、Toyama Shogo、Ikoma Kazuya、Mazda Osam、Mikami Yasuo
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 20 Pages: 5100-5100
- DOI
  10.3390/ijms20205100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K19914, KAKENHI-PROJECT-17H02136, KAKENHI-PROJECT-17H04316, KAKENHI-PROJECT-20K11214
[Journal Article] Pristimerin inhibits the proliferation of HT1080 fibrosarcoma cells by inducing apoptosis2020
- Author(s)
  Hayashi Daichi、Shirai Toshiharu、Terauchi Ryu、Tsuchida Shinji、Mizoshiri Naoki、Mori Yuki、Arai Yuji、Mazda Osam、Kubo Toshikazu
- Journal Title
  
  Oncology Letters
  
  Volume: 19 Pages: 2963-2970
- DOI
  10.3892/ol.2020.11405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22690
[Journal Article] Relationship of alignment in the lower extremity with early degeneration of articular cartilage after resection of the medial meniscus: Quantitative analysis using T2 mapping2020
- Author(s)
  Nakagawa Shuji、Arai Yuji、Inoue Hiroaki、Fujii Yuta、Kaihara Kenta、Mikami Yasuo
- Journal Title
  
  Medicine
  
  Volume: 99
- DOI
  10.1097/md.0000000000022984
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10752, KAKENHI-PROJECT-18K16630
[Journal Article] Clinical outcomes after medial patellofemoral ligament reconstruction: an analysis of changes in the patellofemoral joint alignment2020
- Author(s)
  Fujii Yuta、Nakagawa Shuji、Arai Yuji、Inoue Hiroaki、Kan Hiroyuki、Hino Manabu、Kaihara Kenta、Mikami Yasuo
- Journal Title
  
  International Orthopaedics
  
  Volume: -
- DOI
  10.1007/s00264-020-04765-w
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10752
[Journal Article] Construction of an expression vector containing mouse-rat chimeric genes encoding a therapeutic antibody against CD812019
- Author(s)
  Yamasaki T, Arai Y, Nakagawa S, Kubo T, Nakanishi T
- Journal Title
  
  J Hard Tissue Biol
  
  Volume: 28 Pages: 239-244
- NAID
  130007685302
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08379
[Journal Article] The tetraspanin CD81 mediates the growth and metastasis of human osteosarcoma2019
- Author(s)
  Mizoshiri N, Shirai T, Terauchi R, Tsuchida S, Mori Y, Hayashi D, Kishida T, Arai Y, Nakanishi T, Kubo T
- Journal Title
  
  Cell Oncol
  
  Volume: on line
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08379
[Journal Article] Construction of an Expression Vector Containing Mouse-Rat Chimeric Genes Encoding a Therapeutic Antibody against CD812019
- Author(s)
  Tsutomu Yamasaki, Yuji Arai, Shuji Nakagawa, Toshikazu Kubo and Tohru Nakanishi
- Journal Title
  
  J Hard Tissue Biol
  
  Volume: in press
- NAID
  130007685302
- Data Source
  KAKENHI-PROJECT-17K08379
[Journal Article] The Usefulness of Basic Movement Scale in Hip Fracture Patients2019
- Author(s)
  Goto Ryutaro、Toyama Shogo、Sawada Koshiro、Takamuku Kiyoshi、Kubo Toshikazu、Takahashi Tai
- Journal Title
  
  American Journal of Physical Medicine & Rehabilitation
  
  Volume: 98 Pages: 1099-1105
- DOI
  10.1097/phm.0000000000001254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11420
[Journal Article] The tetraspanin CD81 mediates the growth and metastases of human osteosarcoma2019
- Author(s)
  Mizoshiri Naoki、Shirai Toshiharu、Terauchi Ryu、Tsuchida Shinji、Mori Yuki、Hayashi Daichi、Kishida Tsunao、Arai Yuji、Mazda Osam、Nakanishi Tohru、Kubo Toshikazu
- Journal Title
  
  Cellular Oncology
  
  Volume: 42 Pages: 861-871
- DOI
  10.1007/s13402-019-00472-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02136, KAKENHI-PROJECT-17H04316
[Journal Article] Treadmill Running Ameliorates Destruction of Articular Cartilage and Subchondral Bone, Not Only Synovitis, in a Rheumatoid Arthritis Rat Model2018
- Author(s)
  Shimomura S, Inoue H, Arai Y, Nakagawa S, Fujii Y, Kishida T, Ichimaru S, Tsuchida S, Shirai T, Ikoma K, Mazda O, Kubo T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 Pages: 1653-1653
- DOI
  10.3390/ijms19061653
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10752, KAKENHI-PROJECT-17H02136, KAKENHI-PROJECT-16K15669, KAKENHI-PROJECT-17H04316
[Journal Article] Suppression of heat shock protein 70 by siRNA enhances the anti-tumor effects of cisplatin in cultured human osteosarcoma cells2017
- Author(s)
  Mori Y. et al.
- Journal Title
  
  Cell Stress and Chaperones
  
  Volume: in press
- DOI
  10.1007/s12192-017-0793-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293340, KAKENHI-PROJECT-26462273
[Journal Article] テトラスパニンCD81を標的とする新規次世代リウマチ治療薬の開発2016
- Author(s)
  中西　徹、山崎　勤、新井祐志、中川周士、久保俊一
- Journal Title
  
  アレルギーの臨床
  
  Volume: 36 Pages: 1382-1387
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460165
[Journal Article] Hypoxia potentiates anabolic effects of exogenous hyaluronic acid in rat articular cartilage.2016
- Author(s)
  Ichimaru S. et al.
- Journal Title
  
  International Journal of Molecular Science
  
  Volume: 17
- DOI
  10.3390/ijms17071013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293340, KAKENHI-PROJECT-26462312, KAKENHI-PROJECT-15K15555
[Journal Article] Hydrostatic Pressure Influences HIF-2 Alpha Expression in Chondrocytes2015
- Author(s)
  Hiroaki Inoue, Yuji Arai, Tsunao Kishida, Ryu Terauchi, Kuniaki Honjo, Shuji Nakagawa, Shinji Tsuchida, Tomohiro Matsuki, Keiichirou Ueshima, Hiroyoshi Fujiwara, Osam Mazda, Toshikazu Kubo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 16 Pages: 1043-1050
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390356
[Journal Article] Sonoporation-mediated transduction of siRNA ameliorated experimental arthritis using 3 MHz pulsed ultrasound.2014
- Author(s)
  Inoue H, Arai Y, Kishida T, Shin-Ya, M, Terauchi R, Nakagawa S, Saito M, Tsuchida, S, Inoue A, Shirai T, Fujiwara H, Mazda O, Kubo T
- Journal Title
  
  Ultrasonics
  
  Volume: 54(3)(Epub 2013 Nov 11) Pages: 874-81
- DOI
  10.1016/j.ultras.2013.10.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-24390356
[Journal Article] HIF-1a-Induced HSP70 Regulates Anabolic Responses in Articular Chondrocytes under Hypoxic Conditions2014
- Author(s)
  Tsuchida S, Arai Y, Takahashi KA, Kishida T, Terauchi R, Honjo K, Nakagawa S, Inoue H, Ikoma K, Ueshima K, Matsuki T, Mazda O, Kubo T
- Journal Title
  
  Orthop Res
  
  Volume: (Epub ahead of print) Pages: 975-80
- DOI
  10.1002/jor.22623
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/24677016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-26293340, KAKENHI-PROJECT-26462312, KAKENHI-PROJECT-26670452, KAKENHI-PROJECT-26670485
[Journal Article] Silencing the expression of connexin 43 decreases inflammation and joint destruction in experimental arthritis2013
- Author(s)
  Tsuchida S, Arai Y, Kishida T, Takahashi K, Honjo K, Terauchi R, Inoue H, Oda R, Mazda O, Kubo T.
- Journal Title
  
  J. Orthop. Res
  
  Volume: 31(4) Pages: 525-30
- DOI
  10.1002/jor.22263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-23659731, KAKENHI-PROJECT-24659447, KAKENHI-PROJECT-25670656
[Journal Article] Silencing the expression of connexin 43 decreases inflammation and joint destruction in experimental arthritis.2013
- Author(s)
  Tsuchida S, Arai Y, Kishida T, Takahashi KA, Honjo K, Terauchi R, Inoue H, Oda R, Mazda O, Kubo T.
- Journal Title
  
  Journal of Orthopaedic Reseach
  
  Volume: 31(4) Pages: 525-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659731
[Journal Article] Mild electrical stimulation with heat stimulation increase heat shock protein 70 in articular chondrocyte2013
- Author(s)
  Hiraoka N,Arai Y, Takahashi KA, Mazda O, Kishida T, Honjo K, Tsuchida S, Inoue H, Morino S, Suico MA, Kai H, Kubo T.
- Journal Title
  
  J. Orthop. Res.
  
  Volume: 17 Pages: 894-900
- DOI
  10.1002/jor.22307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-23650333, KAKENHI-PROJECT-24659447, KAKENHI-PROJECT-25670260, KAKENHI-PROJECT-25670656
[Journal Article] Combined microwave irradiation and intraarticular glutamine administr ation-induced HSP70 expression therapy prevents cartilage degradation in a rat osteoarthritis model2012
- Author(s)
  Shinya Fujita, Yuji Arai, Shuji Nakagawa, Kenji A.Takahashi, Ryu Terauchi, Atsuo Inoue, Hitoshi Tonomura, Nobuyuki Hiraoka, Hiroaki Inoue, Shinji Tsuchida, Osam Mazda, Toshikazu Kubo
- Journal Title
  
  JOURNAL OF ORTHOPAEDIC RESEARCH
  
  Volume: 30 Pages: 401-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390404
[Journal Article] Application of tetraspanin CD81 RNAi for diagnosis and therapy of rheumatoid arthritis (RA)2012
- Author(s)
  Nakanishi T, Arai Y, Mori H, Nakajima T, Kubo T
- Journal Title
  
  Arthr Res Therap
  
  Volume: 14 Pages: 52-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590102
[Journal Article] Lansoprazole Inhibits Nitric Oxide and Prostaglandin E(2) Production in Murine Macrophage RAW 264.7 Cells2012
- Author(s)
  Nakagawa S, Arai Y, Kishida T, Hiraoka N, Tsuchida S, Inoue H, Sakai R, Mazda O, Kubo T
- Journal Title
  
  Inflammation
  
  Volume: 35(3)(PMID :22134422)(PubMed - in process) Pages: 1062-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591318
[Journal Article] Combined microwave irradiation and intraarticular glutamine administration-induced HSP70 expression therapy prevents cartilage degradation in a rat osteoarthritis model2012
- Author(s)
  Shinya Fujita, Yuji Arai, Shuji Nakagawa, Kenji A. Takahashi, Ryu Terauchi, Atsuo Inoue, Hitoshi Tonomura, Nobuyuki Hiraoka, Hiroaki Inoue, Shinji Tsuchida, Osam Mazda, Toshikazu Kubo
- Journal Title
  
  Journal of Orthopaedic Reseach
  
  Volume: Vol.30 Pages: 401-407
- URL
  http://onlinelibrary.wiley.com/doi/10.1002/jor.21535/abstract
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390404
[Journal Article] 3. Lansoprazole inhibits nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells.2012
- Author(s)
  Shuji Nakagawa, Yuji Arai, Tsunao Kishida, Nobuyuki Hiraoka, Shinji Tsuchida, Hiroaki Inoue, Ryo Sakai, Osam Mazda, Toshikazu Kubo
- Journal Title
  
  Inflammation.
  
  Volume: Vol.35 Pages: 1062-1068
- DOI
  10.1007/s10753-011-9412-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659276, KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-24659447
[Journal Article] Application of tetraspanin CD81 RNAi for diagnosis and therapy of rheumatoid arthrits (RA)2012
- Author(s)
  Nakanishi T, Arai Y, Mori H, Nakajima T, Kubo T
- Journal Title
  
  Arthr Res Therap
  
  Volume: 14 Pages: 52-52
- Data Source
  KAKENHI-PROJECT-23590102
[Journal Article] Intra-articular injection of hyaluronan restores the aberrant expression of matrix metalloproteinase-13 in osteoarthritic subchondral bone.2011
- Author(s)
  Hiraoka N, Takahashi KA, Arai Y, Sakao K, Mazda O, Kishida T, Honjo K, Tanaka S, Kubo T
- Journal Title
  
  J Orthop Res.
  
  Volume: 29(3) Pages: 354-60
- DOI
  10.1002/jor.21240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591318
[Journal Article] N-Acetylcysteine Prevents Nitric Oxide-Induced Chondrocyte Apoptosis and Cartilage Degeneration in an Experimental Model of Osteoarthritis2010
- Author(s)
  Shuji Nakagawa, Yuji Arai, Osam Mazda, Tsunao Kishida, Kenji A. Takahashi, Kei Sakao, Masazumi Saito, Kuniaki Honjo, Jiro Imanishi, Toshikazu Kubo
- Journal Title
  
  Journal of Orthopaedic Reseach
  
  Volume: Vol.28 Pages: 156-163
- URL
  http://onlinelibrary.wiley.com/doi/10.1002/jor.20976/abstract
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390404
[Journal Article] N-Acetylcysteine Prevents Nitric Oxide-Induced Chondrocyte Apoptosis and Cartilage Degeneration in an Experimental Model of Osteoarthritis2010
- Author(s)
  Shuji Nakagawa, Yuji Arai, Osam Mazda, Tsunao Kishida, Kenji A.Takahashi, Kei Sakao, Masazumi Saito, Kuniaki Honjo, Jiro Imanishi, Toshikazu Kubo
- Journal Title
  
  JOURNAL OF ORTHOPAEDIC RESEARCH
  
  Volume: 28 Pages: 156-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390404
[Journal Article] Small interfering RNA targeting CD81 ameliorated arthritis in rats.2009
- Author(s)
  Nakagawa S, Arai Y, Mori H, Matsushita Y, Kubo T, Nakanishi T
- Journal Title
  
  Biochem Biophys Res Commun 388
  
  Pages: 467-472
- Data Source
  KAKENHI-PROJECT-19390026
[Journal Article] Hyperthermia for the treatment of articular cartilage with osteoarthritis2009
- Author(s)
  Kenji A. Takahashi, Hitoshi Tonomura, Yuji Arai, Ryu Terauchi, Kuniaki Honjo, Nobuyuki Hiraoka, Tatsuya Hojo, Taisuke Kunitomo, Toshikazu Kubo
- Journal Title
  
  International Journal of Hyperthermia
  
  Volume: Vol.25, No8 Pages: 661-667
- URL
  http://informahealthcare.com/doi/abs/10.3109/02656730903107519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390404
[Journal Article] Hyperthermia for the treatment of articular cartilage with osteoarthritis2009
- Author(s)
  Kenji A Takahashi, Toshikazu Kubo
- Journal Title
  
  International Journal of Hyperthermia 25(8)
  
  Pages: 661-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390404
[Journal Article] Effects of heat stimulation via microwave applicator on cartilage matrix gene and HSP70 expression in the rabbit knee joint2008
- Author(s)
  Hitoshi Tonomura, Kenji A. Takahashi, Osam Mazda, Yuji Arai, Masaharu Shin-Ya, Atsuo Inoue, Kuniaki Honjo, Tatsuya Hojo, Jiro Imanishi, Toshikazu Kubo
- Journal Title
  
  Journal of Orthopaedic Reseach
  
  Volume: Vol.26 Pages: 34-41
- URL
  http://onlinelibrary.wiley.com/doi/10.1002/jor.20421/abstract;jsessionid=C846DE7EF515F96FD6959D9EDB20BDBA.d03t02
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390404
[Journal Article] Comparison of anti-rheumatic effcts of Iocal siRNA therapy using various cytokine genes as molecular targets2008
- Author(s)
  Inoue, A; Arai, Y.
- Journal Title
  
  Transaction of Orthopaedic Research Society 33
  
  Pages: 1192-1192
- Data Source
  KAKENHI-PROJECT-18791049
[Journal Article] The gene expression profile of ADAMTS-5 in the synovium of experimental osteoarthritis and gene silencing using small interfering RNA2008
- Author(s)
  Saito, M; Arai, Y.
- Journal Title
  
  Transaction of Orthopaedic Research Society 33
  
  Pages: 671-671
- Data Source
  KAKENHI-PROJECT-18791049
[Journal Article] The therapeuitic effects of inflammatory cytokine-specific small interfering RNA transduction into joints on rat arthritis2007
- Author(s)
  Inoue, A., Arai, Y.
- Journal Title
  
  Transaction of Orthopaedic Research Society 32
  
  Pages: 1460-1460
- Data Source
  KAKENHI-PROJECT-18791049
[Journal Article] The safe and effective delivery of small interfering RNA into the knee joints using sonoporation2007
- Author(s)
  Saito, M., Arai, Y.
- Journal Title
  
  Transaction of Orthopaedic Research Society 32
  
  Pages: 1461-1461
- Data Source
  KAKENHI-PROJECT-18791049
[Journal Article] Hydrostatic pressure induces apoptosis of chondrocytes cultured in alginate beads2006
- Author(s)
  Nakamura, S., Arai, Y
- Journal Title
  
  Journal of Orthopaedic Research 24
  
  Pages: 733-739
- Data Source
  KAKENHI-PROJECT-18791049
[Journal Article] Sonoporation mediated transduction of pDNA/siRNA into joint synovium in vivo
- Author(s)
  Saito, M., Arai, Y.
- Journal Title
  
  Journal of Orthopaedic Research (in press)
- Data Source
  KAKENHI-PROJECT-18791049
[Presentation] Influence of heat stress on SIRT1-transfected chondrocytes2021
- Author(s)
  Kaihara K, Inoue H, Nakagawa S, Arai Y, Fujii Y, Mazda O, Takahashi K
- Organizer
  2021 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09507
[Presentation] 酸素濃度がヒトiPS細胞から軟骨組織への分化に与える影響2021
- Author(s)
  藤井雄太，井上裕章，下村征史，中川周士，市丸昌平，鎌田陽一郎，貝原健太，松田　修，新井祐志
- Organizer
  第33回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-18K19620
[Presentation] Treadmill running suppressed joint destruction in a rheumatoid arthritis rat model2020
- Author(s)
  Fujii Y, Inoue H, Arai Y, Shimomura S, Nakagawa S, Tsuchida S, Kamada Y, Kaihara K, Mazda O, Mikami Y
- Organizer
  66th Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19620
[Presentation] Effect Of Hif-1α Stabilization By Deferoxamine On Chondrocyte And Articular Cartilage2020
- Author(s)
  Kaihara Kenta、Nakagawa Shuji、Arai Yuji、Fujii Yuta、Inoue Hiroaki、Tsuchida Shinji、Kamada Yoichiro、Mazda Osam、Mikami Yasuo
- Organizer
  66th Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05452
[Presentation] Effect of hif-1α stabilization by deferoxamine on chondrocyte and articular cartilage2020
- Author(s)
  Kaihara K, Nakagawa S, Arai Y, Fujii Y, Inoue H, Tsuchida S, Kamada Y, Mazda O, Mikami Y
- Organizer
  66th Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10752
[Presentation] Effect Of Hif-1α Stabilization By Deferoxamine On Chondrocyte And Articular Cartilage2020
- Author(s)
  Kaihara Kenta、Nakagawa Shuji、Arai Yuji、Fujii Yuta、Inoue Hiroaki、Tsuchida Shinji、Kamada Yoichiro、Mazda Osam、Mikami Yasuo
- Organizer
  66th Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02136
[Presentation] 関節リウマチ症例への積極的なリハビリテーション治療の工夫2020
- Author(s)
  遠山将吾，菱川法和，小田　良，沢田光思郎，徳永大作，高橋謙治，三上靖夫
- Organizer
  第35回日本臨床リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K11420
[Presentation] Treadmill Running Suppressed Joint Destruction In A Rheumatoid Arthritis Rat Model2020
- Author(s)
  Yuta Fujii; Hiroaki Inoue; Yuji Arai; Seiji Shimomura; Shuji Nakagawa; Shinji Tsuchida; Yoichiro Kamada; Kenta Kaihara; Osam Mazda; Yasuo Mikami
- Organizer
  2020 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10752
[Presentation] トレッドミル走行がラット関節炎モデルの足関節に与える影響2020
- Author(s)
  藤井雄太，井上裕章，中川周士，下村征史，新井祐志，松田　修，高橋謙治
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K19620
[Presentation] Treadmill running suppressed joint destruction in a rheumatoid arthritis rat model2020
- Author(s)
  Fujii Y, Inoue H, Arai Y, Shimomura S, Nakagawa S, Tsuchida S, Kamada Y, Kaihara K, Mazda O, Mikami Y
- Organizer
  66th Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10752
[Presentation] 関節リウマチにおけるサルコペニア2020
- Author(s)
  遠山将吾，菱川法和，小田　良，沢田光思郎，徳永大作，高橋謙治，三上靖夫
- Organizer
  第48回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K11420
[Presentation] Analysis of reaction to tensile stress in chondrocytes in hypoxic environment2020
- Author(s)
  Kamada Y, Inoue H, Arai Y, Shimomura S, Nakagawa S, Tsuchida S, Fujii Y, Kaihara K, Mazda O, Mikami Y
- Organizer
  66th Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10752
[Presentation] Analysis Of Reaction To Tensile Stress In Chondrocytes In Hypoxic Environment2020
- Author(s)
  Yoichiro Kamada; Hiroaki Inoue; Yuji Arai; Seiji Shimomura; Shuji Nakagawa; Shinji Tsuchida; Yuta Fujii; Kenta Kaihara; Osam Mazda; Yasuo Mikami
- Organizer
  2020 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19620
[Presentation] SIRT1導入細胞に対する温熱ストレスの検討2020
- Author(s)
  貝原健太，井上裕章，中川周士，新井祐志，藤井雄太，松田修，高橋謙治
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K09507
[Presentation] Analysis Of Reaction To Tensile Stress In Chondrocytes In Hypoxic Environment2020
- Author(s)
  Kamada Yoichiro、Inoue Hiroaki、Arai Yuji、Shimomura Seiji、Nakagawa Shuji、Tsuchida Shinji、Fujii Yuta、Kaihara Kenta、Mazda Osam、Mikami Yasuo
- Organizer
  66th Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02136
[Presentation] トレッドミル走行がラット関節炎モデルの足関節に与える組織学的影響2019
- Author(s)
  藤井雄太，井上裕章，新井祐志，下村征史，中川周士，土田真嗣，鎌田陽一郎，貝原健太，松田　修，久保俊一
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K10752
[Presentation] 新規関節リウマチ抗体薬開発のためのキメラ抗体作製2019
- Author(s)
  山崎勤、新井祐志、中川周士、久保俊一、中西　徹
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08379
[Presentation] Hypoxic Condition Promotes Differentiation From Human iPSC to Cartilage2019
- Author(s)
  Shimomura S, Inoue H, Arai Y, Nakagawa S, Tsuchida S, Ichimaru S, Fujii Y, Mazda O, Kubo T
- Organizer
  65th Annual Meeting of Orthopaedic Research Society
- Data Source
  KAKENHI-PROJECT-17H02136
[Presentation] Efficacy of pristimerin for soft tissue sarcoma in vitro and in vivo study2019
- Author(s)
  Daichi Hayashi, Toshiharu Shirai, Ryu Terauchi, Shinji Tsuchida, Naoki Mizoshiri, Yuki Mori, Yuji Arai, Osam Mazda, Toshikazu Kubo
- Organizer
  ORS　2019　Annual　Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10975
[Presentation] 低酸素環境下における伸展刺激に対する軟骨細胞のストレス応答解析2019
- Author(s)
  鎌田陽一郎、井上裕章、新井祐志、下村征史、中川周士、土田真嗣、松田　修、久保俊一
- Organizer
  日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17H02136
[Presentation] Treadmill Running Ameliorates Articular Cartilage Destruction and Synovitis Histologically in a Rheumatoid Arthritis Rat Model2019
- Author(s)
  Fujii Y, Inoue H, Arai Y, Shimomura S, Nakagawa S, Tsuchida S, Ichimaru S, Mazda O, Kubo T
- Organizer
  65th Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10752
[Presentation] 関節リウマチにおけるキメラ抗体の作製2019
- Author(s)
  山崎勤、中川周士、新井祐志、久保俊一、中西　徹
- Organizer
  日本薬学会139年会
- Data Source
  KAKENHI-PROJECT-17K08379
[Presentation] 新規関節リウマチ治療薬のターゲットCD81に対する抗体薬の開発2019
- Author(s)
  山崎勤、中川周士、新井祐志、久保俊一、中西　徹
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08379
[Presentation] 天然有機化合物であるプリスチメリンの骨肉腫細胞に対する抗腫瘍効果2018
- Author(s)
  林大智，白井寿治，寺内竜，土田真嗣，溝尻直毅，森裕貴，勝山祐誠，新井祐志，松田修，久保俊一
- Organizer
  日本整形外科学会骨・軟部腫瘍学会
- Data Source
  KAKENHI-PROJECT-17K10975
[Presentation] ヒトiPS細胞から軟骨組織分化における酸素濃度の影響の検討2018
- Author(s)
  下村征史，井上裕章，新井祐志，中川周士，土田真嗣，市丸昌平，藤井雄太，松田　修，久保俊一
- Organizer
  第33回日本整形外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K19620
[Presentation] トレッドミル走行がラット関節炎モデルの膝関節に与える組織学的評価2018
- Author(s)
  藤井雄太，井上裕章，新井祐志，中川周士，土田真嗣，下村征史，松田　修，久保俊一
- Organizer
  第33回日本整形外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-17H02136
[Presentation] Histological evaluation of treadmill running on knee joint of rat arthritis model2018
- Author(s)
  Fujii Y, Inoue H, Arai Y, Nakagawa S, Tsuchida S, Shimomura S, Mazda O, Kubo T
- Organizer
  26th Annual Meeting of European Orthopaedic Reserch Society
- Data Source
  KAKENHI-PROJECT-17H02136
[Presentation] HIF-1α in articular cartilage is up-regulated by treadmill running in vivo2018
- Author(s)
  Fujii Y, Inoue H, Arai Y, Nakagawa S, Tsuchida S, Shimomura S, Mazda O, Kubo T
- Organizer
  21st World Congress of the Osteoarthritis Research Society International (OARSI)
- Data Source
  KAKENHI-PROJECT-17H02136
[Presentation] The effects of treadmill exercise at a single time on knee articular cartilage in vivo2018
- Author(s)
  Shimomura S, Inoue H, Arai Y, Nakagawa S, Tsuchida S, Ichimaru S, Fujii Y, Mazda O, Kubo T
- Organizer
  26th Annual Meeting of European Orthopaedic Reserch Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19620
[Presentation] Effects of hypoxic conditions in differentiation of human iPSC to cartilage2018
- Author(s)
  Seiji Shimomura, Hiroaki Inoue, Yuji Arai, Shuji Nakagawa, Shinji Tsuchida, Shohei Ichimaru, Yuta Fujii, Osamu Mazda, Toshikazu Kubo
- Organizer
  2018　ORS　annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05452
[Presentation] Effects of hypoxic conditions in differentiation of human iPSC to cartilage2018
- Author(s)
  Seiji Shimomura, Hiroaki Inoue, Yuji Arai, Shuji Nakagawa, Shinji Tsuchida,Shohei Ichimaru, Yuta Fujii, Osamu Mazda, Toshikazu Kubo
- Organizer
  64th Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02136
[Presentation] 天然有機化合物であるプリスチメリンの線維肉腫細胞に対する抗腫瘍効果2018
- Author(s)
  林　大智，白井寿治，寺内竜，土田真嗣，溝尻直毅，森　裕貴，勝山祐誠，新井祐志，松田修，久保俊一
- Organizer
  日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K10975
[Presentation] The effect of treadmill running on knee articular cartilage in rats2017
- Author(s)
  Seiji Shimomura, Hiroaki Inoue, Yuji Arai, Shuji Nakagawa, Shinji Tsuchida, Shohei Ichimaru, Osam Mazda, Toshikazu Kubo
- Organizer
  20th World Congress of the Osteoarthritis Research Society International (OARSI)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462312
[Presentation] 低酸素環境によるヒトiPS細胞から軟骨組織への分化促進効果の検討2017
- Author(s)
  下村征史，井上裕章，新井祐志，中川周士，土田真嗣，市丸昌平，松田　修，久保俊一
- Organizer
  第32回日本整形外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-16H05452
[Presentation] Regulation of inflammatory cytokine expression and osteoclastgenesis by gap junctional protein in vitro and in vivo.2017
- Author(s)
  Seiji Shimomura, Shinji Tsuchida, Yuji Arai, Shuji Nakagawa, Hiroaki Inoue, Shohei Ichimaru, Yuta Fujii, Osam Mazda, Toshikazu Kubo
- Organizer
  The 5th annual meeting of the international cytokine and interferon society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02136
[Presentation] Regulation of inflammatory cytokine expression and osteoclastgenesis by gap junctional protein in vitro and in vivo.2017
- Author(s)
  Seiji Shimomura, Shinji Tsuchida, Yuji Arai, Shuji Nakagawa, Hiroaki Inoue, Shohei Ichimaru, Yuta Fujii, Osam Mazda, Toshikazu Kubo
- Organizer
  The 5th annual meeting of the international cytokine and interferon society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462312
[Presentation] The effect of treadmill running on knee articular cartilage in rats2017
- Author(s)
  Seiji Shimomura, Hiroaki Inoue, Yuji Arai, Shuji Nakagawa, Shinji Tsuchida, Shohei Ichimaru, Osam Mazda, Toshikazu Kubo
- Organizer
  20th World Congress of the Osteoarthritis Research Society International (OARSI)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15555
[Presentation] テトラスパニンCD81を標的とした新規次世代リウマチ治療薬の開発2017
- Author(s)
  中西　徹、山崎　勤、新井祐志、中川周士、久保俊一
- Organizer
  硬組織再生生物学会
- Data Source
  KAKENHI-PROJECT-17K08379
[Presentation] The anti-tumor effect of chemotherapy on human osteosarcoma cell line in combination with suppression of heat shock protein2017
- Author(s)
  Mori Y, Terauchi R, Shirai T, Tsuchida S, Mizoshiri N, Arai Y, Mazda O, Kubo T
- Organizer
  ORS 2017 Annual Meeting
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2017-03-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462273
[Presentation] The effect of treadmill running on knee articular cartilage in rats2017
- Author(s)
  Seiji Shimomura, Hiroaki Inoue, Yuji Arai, Shuji Nakagawa, Shinji Tsuchida, Shohei Ichimaru, Osam Mazda, Toshikazu Kubo
- Organizer
  20th World Congress of the Osteoarthritis Research Society International (OARSI)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02136
[Presentation] 天然有機化合物であるプリスチメリンの骨肉腫細胞株に対する抗腫瘍効果の検討2017
- Author(s)
  森裕貴，白井寿治，寺内竜，土田真嗣，溝尻直毅，新井祐志，松田修，久保俊一
- Organizer
  第32回　日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K10975
[Presentation] トレッドミル走行がラット膝関節軟骨に与える影響2016
- Author(s)
  下村征史，井上裕章，新井祐志，中川周士，土田真嗣，市丸昌平，松田　修，久保俊一
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26462312
[Presentation] Pharmacological effects of exogenous hyaluronic acid in articular cartilage under hypoxia2016
- Author(s)
  Ichimaru S, Nakagawa S, Arai Y, Tsuchida S, Inoue H, Shimomura S, Mazda O, Kubo T
- Organizer
  第29回日本軟骨代謝学会
- Place of Presentation
  広島
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] The anti-tumor effect of chemotherapy on human osteosarcoma cell line in combination with suppression of heat shock protein2016
- Author(s)
  Mori Y, Terauchi R, Shirai T, Tsuchida S, Mizoshiri N, Arai Y, Mazda O, Kubo T
- Organizer
  EUROPEAN ORTHOPAEDIC RESEARCH SOCIETY 24th ANNUAL MEETING
- Place of Presentation
  Bologna,Italy
- Year and Date
  2016-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462273
[Presentation] Pharmacological effects of exogenous hyaluronan in articular cartilage under hypoxia2016
- Author(s)
  Ichimaru S, Nakagawa S, Arai Y, Tsuchida S, Inoue H, Shimomura S, Mazda O, Kubo T
- Organizer
  19th World Congress of the Osteoarthritis Research Society International (OARSI)
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2016-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15555
[Presentation] 低酸素環境下における外因性ヒアルロン酸の薬理効果の変化2016
- Author(s)
  市丸昌平，中川周士，新井祐志，土田真嗣，井上裕章，下村征史，松田　修，久保俊一
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K15555
[Presentation] 骨肉腫細胞株に対する化学療法と熱タンパク抑制法を併用した抗腫瘍効果の検討2016
- Author(s)
  森裕貴,寺内竜,白井寿治,土田真嗣,溝尻直毅,新井祐志,松田修,久保俊一
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26462273
[Presentation] トレッドミル走行がラット膝関節軟骨に与える影響2016
- Author(s)
  下村征史，井上裕章，新井祐志，中川周士，土田真嗣，市丸昌平，松田　修，久保俊一
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K15555
[Presentation] 骨肉腫細胞株に対する化学療法と熱タンパク抑制法を併用した抗腫瘍効果の検討2016
- Author(s)
  森裕貴,寺内竜,白井寿治,土田真嗣,溝尻直毅,新井祐志,松田修,久保俊一
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K10454
[Presentation] 骨肉腫細胞株に対する化学療法と熱タンパク抑制法を併用した抗腫瘍効果の検討2016
- Author(s)
  森裕貴,寺内竜,白井寿治,土田真嗣,溝尻直毅,新井祐志,松田修,久保俊一
- Organizer
  第49回日本整形外科学会　骨・軟部腫瘍学術集会
- Place of Presentation
  東京
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-26462273
[Presentation] Pharmacological effects of exogenous hyaluronic acid in articular cartilage under hypoxia2016
- Author(s)
  Ichimaru S, Nakagawa S, Arai Y, Tsuchida S, Inoue H, Shimomura S, Mazda O, Kubo T
- Organizer
  第29回日本軟骨代謝学会
- Place of Presentation
  広島
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-15K15555
[Presentation] 低酸素環境下における外因性ヒアルロン酸の薬理効果の変化2016
- Author(s)
  市丸昌平，中川周士，新井祐志，土田真嗣，井上裕章，下村征史，松田　修，久保俊一
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26462312
[Presentation] Pharmacological effects of exogenous hyaluronic acid in articular cartilage under hypoxia2016
- Author(s)
  Ichimaru S, Nakagawa S, Arai Y, Tsuchida S, Inoue H, Shimomura S, Mazda O, Kubo T
- Organizer
  第29回日本軟骨代謝学会
- Place of Presentation
  広島
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-26462312
[Presentation] Pharmacological effects of exogenous hyaluronan in articular cartilage under hypoxia2016
- Author(s)
  Ichimaru S, Nakagawa S, Arai Y, Tsuchida S, Inoue H, Shimomura S, Mazda O, Kubo T
- Organizer
  19th World Congress of the Osteoarthritis Research Society International (OARSI)
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2016-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462312
[Presentation] 低酸素環境下にある軟骨細胞に対する外因性ヒアルロン酸の薬理効果2015
- Author(s)
  市丸昌平，中川周士，新井祐志，土田真嗣，井上裕章，本城邦晃，白井寿治，寺内　竜，松田　修，久保俊一
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26462312
[Presentation] HSP70 induced by HIF-1α regulates anabolic responses in chondrocytes under hypoxic conditions2015
- Author(s)
  Honjo K, Arai Y, Tsuchida S, Nakagawa S, Inoue H, Saito M, Ichimaru S, Shimomura S, Inoue A, Terauchi R, Mazda O, Kubo T
- Organizer
  18th World Congress of the Osteoarthritis Research Society International (OARSI)
- Place of Presentation
  Seattle, USA
- Year and Date
  2015-04-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] 低酸素環境下にある軟骨細胞に対する外因性ヒアルロン酸の薬理効果2015
- Author(s)
  市丸昌平，中川周士，新井祐志，土田真嗣，井上裕章，本城邦晃，白井寿治，寺内　竜，松田　修，久保俊一
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] HSP70 induced by HIF-1α regulates anabolic responses in chondrocytes under hypoxic conditions.2015
- Author(s)
  Honjo K, Arai Y, Tsuchida S, Nakagawa S, Inoue H, Saito M, Ichimaru S, Shimomura S, Inoue A, Terauchi R, Mazda O, Kubo T
- Organizer
  18th World Congress of the Osteoarthritis Research Society International (OARSI)
- Place of Presentation
  Seattle, U.S.A
- Year and Date
  2015-04-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15555
[Presentation] 低酸素環境下にある軟骨細胞に対する外因性ヒアルロン酸の薬理効果2015
- Author(s)
  市丸昌平，中川周士，新井祐志，土田真嗣，井上裕章，本城邦晃，白井寿治，寺内　竜，松田　修，久保俊一
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15K15555
[Presentation] The expression levels of connexin 43 in human synovium of rheumatoid arthritis2014
- Author(s)
  Tomohiro Matsuki, Yuji Arai, Shinji Tsuchida, Ryu Terauchi, Hiroaki Inoue, Shuji Nakagawa, Atsuo Inoue, Kuniaki Honjo, Toru Morihara, Toshiharu Shirai, Osam Mazda, Toshikazu Kubo
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-24659683
[Presentation] Sonoporation-mediated transduction of siena targeting TNF alpha ameliorated experimental arthritis2014
- Author(s)
  Inoue H, Arai Y, Terauchi R, Nakagawa S, Saito M, Tsuchida S, Inoue A, Matsuki T, Morihara T, Shirai T, Mazda O, Kubo T
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-24659683
[Presentation] Anti-inflammatory effects of lansoprazole by suppressing ROS production in murine macrophage RAW 264.7 cells2014
- Author(s)
  S. Ichimaru, S. Nakagawa, Y. Arai, S. Tsuchida, H. Inoue, T. Matsuki, Y. Mikami, T. Ikeda, R. Oda, O. Mazda, T. Kubo
- Organizer
  2014 Orthopaedic Research Society Annual Meeting
- Place of Presentation
  New Orleans, Louisiana, USA
- Year and Date
  2014-03-16
- Data Source
  KAKENHI-PROJECT-23591318
[Presentation] Anti-inflammatory effects of lansoprazole by suppressing ROS production in murine macrophage RAW 264.7 cells2014
- Author(s)
  S. Ichimaru, S. Nakagawa, Y. Arai, S. Tsuchida, H. Inoue, T. Matsuki, Y. Mikami, T. Ikeda, R. Oda, O. Mazda, T. Kubo
- Organizer
  2014 Orthopaedic Research Society Annual Meeting
- Place of Presentation
  New Orleans, Louisiana, USA
- Year and Date
  2014-03-16
- Data Source
  KAKENHI-PROJECT-25670656
[Presentation] Anti-inflammatory effects of lansoprazole by suppressing ROS production in murine macrophage RAW 264.7 cells2014
- Author(s)
  Shohei Ichimaru, Shuji Nakagawa, Yuji Arai, Shinji Tsuchida, Hiroaki Inoue, Tomohiro Matsuki, Yasuo Mikami, Takumi Ikeda, Ryo Oda, Osam Mazda, Toshikazu Kubo
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-24659683
[Presentation] Sonoporation-mediated transduction of siRNA targeting TNF alpha ameliorated experimental arthritis2014
- Author(s)
  Inoue H, Arai Y, Nakagawa S, Saito M ,Tsuchida S, Inoue A, Matsuki T, Morihara T, Shirai T, Mazda, O, Kubo T
- Organizer
  60th Annual Meeting of OrthopaedicResearch Society
- Place of Presentation
  New Orleans, Louisiana, USA
- Data Source
  KAKENHI-PROJECT-25670656
[Presentation] Sonoporation-mediated transduction of siRNA targeting TNF alpha ameliorated experimental arthritis2014
- Author(s)
  Inoue H, Arai Y, Nakagawa S, Saito M ,Tsuchida S, Inoue A, Matsuki T, Morihara T, Shirai T, Mazda, O, Kubo T
- Organizer
  60th Annual Meeting of Orthopaedic Research Society
- Place of Presentation
  New Orleans, Louisiana, USA
- Data Source
  KAKENHI-PROJECT-23591318
[Presentation] テトラスパニンCD81を標的とする新規リウマチ治療薬の開発2014
- Author(s)
  中川周士、新井祐志、森宏樹、松下有美、久保俊一、中西徹
- Organizer
  日本薬学会
- Place of Presentation
  熊本
- Year and Date
  2014-03-27
- Data Source
  KAKENHI-PROJECT-23590102
[Presentation] The roles of heat shock protein 70 on chondrocyte2013
- Author(s)
  Matsuki T, Arai Y, Tsuchida S, Terauchi R, Inoue H, Nakagawa S, Inoue A, Mazda O, Kubo T
- Organizer
  16th World Congress of the Osteoarthritis Research Society International
- Place of Presentation
  Philadelphia, USA.
- Year and Date
  2013-04-18
- Data Source
  KAKENHI-PROJECT-25670656
[Presentation] The roles of heat shock protein 70 on chondrocyte2013
- Author(s)
  Matsuki T, Arai Y, Tsuchida S, Terauchi R, Inoue H, Nakagawa S, Inoue A, Mazda O, Kubo T.
- Organizer
  16th World Congress of the Osteoarthritis Research Society International
- Place of Presentation
  Philadelphia, U.S.A
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] The roles of heat shock protein 70 on chondrocyte2013
- Author(s)
  Matsuki T, Arai Y, Tsuchida S, Terauchi R, Inoue H, Nakagawa S, Inoue A, Mazda O, Kubo T
- Organizer
  16th World Congress of the Osteoarthritis Research Society International (OARSI)
- Place of Presentation
  Philadelphia, U.S.A
- Year and Date
  2013-04-18
- Data Source
  KAKENHI-PROJECT-24659683
[Presentation] 関節リウマチ滑膜におけるconnexin43の発現2013
- Author(s)
  松木智宏、新井祐志、土田真嗣、本城邦晃、中川周士、井上裕章、寺内竜、松田修、久保俊一
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24659683
[Presentation] Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes2013
- Author(s)
  Inoue H, Arai Y, Terauchi R, Nakagawa S, Saito M, Hiraoka N, Tsuchida S, Matsuki T, Mazda O, Kubo T
- Organizer
  16th World Congress of the Osteoarthritis Research Society International (OARSI)
- Place of Presentation
  Philadelphia, U.S.A
- Year and Date
  2013-04-18
- Data Source
  KAKENHI-PROJECT-24659683
[Presentation] Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes2013
- Author(s)
  Inoue H, Arai Y, Terauchi R, Nakagawa S, Saito M, Hiraoka N, Tsuchida S, Matsuki T, Mazda Osam, Kubo T
- Organizer
  16th World Congress of the Osteoarthritis Research Society International
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23591318
[Presentation] 低酸素環境下の軟骨細胞におけるheat shock protein 70の役割2013
- Author(s)
  土田真嗣,新井祐志,寺内竜,中川周士,井上敦夫,平岡延之,井上裕章,齊藤正純,松木智宏,久保俊一
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2013-03-02
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] ソノポレーションで導入したTNF-α特異的siRNAによる関節炎モデルの治療効果2013
- Author(s)
  井上裕章,新井祐志,中川周士,寺内竜,土田真嗣,松木智宏,井上敦夫,齊藤正純,松田修,久保俊一
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉県
- Year and Date
  2013-10-18
- Data Source
  KAKENHI-PROJECT-24659683
[Presentation] Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes2013
- Author(s)
  Inoue H, Arai Y, Terauchi R, Nakagawa S, Saito M, Hiraoka N, Tsuchida S, Matsuki T, Mazda O, Kubo T.
- Organizer
  16th World Congress of the Osteoarthritis Research Society International
- Place of Presentation
  Philadelphia, U.S.A
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes2013
- Author(s)
  Inoue H, Arai Y, Terauchi R, Nakagawa S, Saito M, Hiraoka N, Tsuchida S, Matsuki T, Mazda Osam, Kubo T
- Organizer
  16th World Congress of the Osteoarthritis Research Society International
- Place of Presentation
  Philadelphia, USA.
- Data Source
  KAKENHI-PROJECT-25670656
[Presentation] 活性化マクロファージに対するROSを介したランソプラゾールの抗炎症効果の解析2013
- Author(s)
  市丸昌平,中川周士,新井祐志,土田真嗣,井上裕章,松木智宏,久保俊一
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉県
- Year and Date
  2013-10-17
- Data Source
  KAKENHI-PROJECT-24659683
[Presentation] 変形性関節症の最新療法2013
- Author(s)
  新井祐志
- Organizer
  第40回日本生体電気・物理刺激研究会
- Place of Presentation
  ウェスティン都ホテル京都
- Data Source
  KAKENHI-PROJECT-24659683
[Presentation] 温熱刺激とグルタミンを併用したHSP70誘導法による変形性関節症に対する進行抑制効果の検討2013
- Author(s)
  松木智宏，新井祐志，藤田伸弥，井上裕章，中川周士，土田真嗣，寺内　竜，井上敦夫，齊藤正純，松田　修，久保俊一
- Organizer
  第40回日本生体電気・物理刺激研究会
- Place of Presentation
  ウェスティン都ホテル京都
- Data Source
  KAKENHI-PROJECT-23650333
[Presentation] The roles of heat shock protein 70 on chondrocyte2013
- Author(s)
  Matsuki T, Arai Y, Tsuchida S, Terauchi R, Inoue H, Nakagawa S, Inoue A, Mazda O, Kubo T
- Organizer
  16th World Congress of the Osteoarthritis Research Society International
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23591318
[Presentation] 活性化マクロファージに対するランソプラゾールの抗炎症効果の解析2013
- Author(s)
  中川周士，新井祐志，井上裕章，土田真嗣，小田　良，徳永大作，川人　豊，妹尾高宏，久保俊一
- Organizer
  第57回日本リウマチ学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] Silencing the Expression of Connexin 43 Decreases Inflammation in Rat Synovium2012
- Author(s)
  Tsuchida S, Arai Y, Terauchi R, Honjo K, Nakagawa S, Inoue H, Oda R, Tokunaga D, Mazda O, Kubo T
- Organizer
  58th Annual Meeting of Orthopaedic Research Society
- Place of Presentation
  Moscone West Convention Center(San Francisco, California)
- Data Source
  KAKENHI-PROJECT-23659731
[Presentation] 低酸素環境下の軟骨細胞におけるheat shock protein 70の役割2012
- Author(s)
  土田真嗣,新井祐志,寺内竜,井上裕章,齊藤正純,平岡延之,松田修,久保俊一
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] Regulation of osteoclastogenesis by connexin 43 in vitro and in vivo2012
- Author(s)
  土田真嗣,新井祐志,寺内竜,本城邦晃,井上裕章,小田良,徳永大作,久保俊一
- Organizer
  第56回日本リウマチ学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2012-04-25
- Data Source
  KAKENHI-PROJECT-23659731
[Presentation] グルタミン投与と温熱刺激の併用による軟骨細胞へのHSP70発現誘導2012
- Author(s)
  井上裕章、新井祐志、藤田伸弥、中川周士、寺内竜、土田真嗣、齊藤正純、久保俊一
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  ウィル愛知（愛知県）
- Data Source
  KAKENHI-PROJECT-23650333
[Presentation] 温熱刺激とグルタミンの併用によるHSP70誘導療法のラット変形性関節症に対する進行抑制効果2012
- Author(s)
  井上裕章，新井祐志，藤田伸弥，中川周士，土田真嗣，寺内　竜，井上敦夫，齊藤正純，松田　修，久保俊一
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23650333
[Presentation] 低酸素環境がHSP70と軟骨細胞外基質合成に与える影響2011
- Author(s)
  土田真嗣, 新井祐志, 寺内竜, 本城邦晃, 中川周士, 平岡延之, 井上裕章, 齊藤正純, 久保俊一
- Organizer
  第24回日本軟骨代謝学会
- Place of Presentation
  九州大学医学部百年講堂(福岡県)
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-20390404
[Presentation] Effect of hypoxia on cartilage matrix gene and heat shock protein 70 expression in cultured chondrocytes2011
- Author(s)
  Shinji Tsuchida, Yuji Arai, Ryu Terauchi, Kuniaki Honjo, Shuji Nakagawa, Nobuyuki Hiraoka, Hiroaki Inoue, Masazumi Saito, Osam Mazda, Tsunao Kishida, Toshikazu Kubo
- Organizer
  57th Annual Meeting of Orthopaedic Research Society
- Place of Presentation
  Long Beach Convention Center(Long Beach, CA, USA)
- Data Source
  KAKENHI-PROJECT-20390404
[Presentation] The effect of connexin43 for pro-inflammatory cytokines in rat FLSｓ2011
- Author(s)
  土田真嗣，新井祐志，寺内　竜，本城邦晃，中川周士，井上裕章，小田　良，徳永大作，久保俊一
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-23659731
[Presentation] Effect of hypoxia on the expression of cartilage matrix gene and heat shock protein 70 in cultured chondrocytes2011
- Author(s)
  Tsuchida S, Arai Y, Terauchi R, Honjo K, Inoue H, Saito M, Mazda O, Kubo T
- Organizer
  14th World Congress of the Osteoarthritis Research Society International (OARSI)
- Place of Presentation
  Hilton San Diego Bayfront (San Diego, CA)
- Data Source
  KAKENHI-PROJECT-20390404
[Presentation] Effect of hypoxia on the expression of cartilage matrix gene and heat shock protein 70 in cultured chondrocytes2011
- Author(s)
  Shinji Tsuchida, Yuji Arai, Ryu Terauchi, Kuniaki Honjo, Hiroaki Inoue, Masazumi Saito, Osam Mazda, Toshikazu Kubo
- Organizer
  14th World Congress of the Osteoarthritis Research Society International(OARSI)
- Place of Presentation
  Hilton San Diego Bayfront(San Diego, CA, USA)
- Data Source
  KAKENHI-PROJECT-20390404
[Presentation] Effect of hypoxia on cartilage matrix gene and heat shock protein 70 expression in cultured chondrocytes2011
- Author(s)
  Tsuchida S, Arai Y, Terauchi R, Honjo K, Nakagawa S, Hiraoka N, Inoue H, Saito M, Mazda O, Kishida T, Kubo T
- Organizer
  57th Annual Meeting of Orthopaedic Research Society
- Place of Presentation
  Long Beach Convention Center (Long Beach, CA)
- Data Source
  KAKENHI-PROJECT-20390404
[Presentation] 低酸素環境およびHIF-1αが培養軟骨におけるHSP70と軟骨細胞外基質合成に与える影響2011
- Author(s)
  土田真嗣, 新井祐志, 寺内竜, 本城邦晃, 中川周士, 平岡延之, 井上裕章, 齊藤正純, 松田修, 久保俊一
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  ベイシア文化ホール(群馬県)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-20390404
[Presentation] 関節軟骨の分子生物学的研究―ストレス応答を中心に―
- Author(s)
  新井祐志
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] ソノポレーションで導入したTNF-α特異的siRNAによる関節炎モデルの治療効果
- Author(s)
  井上裕章，新井祐志，中川周士，寺内　竜，土田真嗣，松木智宏，井上敦夫，齊藤正純，松田　修，久保俊一
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] Effect of inflammation stress on the hypertrophic differentiation-related gene expression in cultured chondrocytes
- Author(s)
  Inoue Hiroaki, Arai Yuji, Terauchi Ryu, Nakagawa Shuji, Saito Masazumi, Tsuchida Shinji, Matsuki Tomohiro, Ichimaru Shohei, Mazda Osam,Kubo Toshikazu
- Organizer
  2015 OARSI World Congress
- Place of Presentation
  Paris, France
- Year and Date
  2014-04-24 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] 活性化マクロファージに対するROSを介したランソプラゾールの抗炎症効果の解析
- Author(s)
  市丸昌平，中川周士，新井祐志，土田真嗣，井上裕章，松木智宏，久保俊一
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] The anabolic effects of HIF-1α-induced HSP70 in rabbit articular chondrocyte under hypoxic conditions
- Author(s)
  Shohei Ichimaru, Shinji Tsuchida, Yuji Arai, Shuji Nakagawa, Hiroaki Inoue, Tomohiro Matsuki, Kuniaki Honjo, Keiichiro Ueshima, Osam Mazda, Toshikazu Kubo
- Organizer
  Orthopaedic Research Society 2015 annual meeting
- Place of Presentation
  Las Vegas
- Year and Date
  2015-03-28 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-26462312
[Presentation] テトラスパニンCD81を標的とする新規リウマチ治療薬の開発
- Author(s)
  中川周士、新井祐志、森　宏樹、松下有美、久保俊一、中西　徹
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-23590102
[Presentation] トレッドミル走行がラット膝関節軟骨に与える影響
- Author(s)
  松木智宏，新井祐志，中川周士，土田真嗣，井上裕章，寺内　竜，井上敦夫，久保俊一
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390356
[Presentation] 活性化マクロファージに対する一酸化窒素の産生抑制によるランソプラゾールの抗炎症効果の解析
- Author(s)
  市丸昌平，中川周士，新井祐志，土田真嗣，井上裕章，松木智宏，谷口大吾，小田　良，藤原浩芳，久保俊一
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390356

1. NAKAGAWA Shuji (30643382)

# of Collaborated Projects: 12 results

# of Collaborated Products: 49 results
2. KUBO Toshikazu (20178031)

# of Collaborated Projects: 10 results

# of Collaborated Products: 71 results
3. Mazda Osam (00271164)

# of Collaborated Projects: 8 results

# of Collaborated Products: 32 results
4. NAKANISHI Tohru (30243463)

# of Collaborated Projects: 6 results

# of Collaborated Products: 14 results
5. KISHIDA Tsunao (00370205)

# of Collaborated Projects: 6 results

# of Collaborated Products: 8 results
6. TERAUCHI Ryu (20575154)

# of Collaborated Projects: 6 results

# of Collaborated Products: 31 results
7. NAGATSUKA Hitoshi (70237535)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. 井上裕章 (60457968)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
9. Shirai Toshiharu (20397186)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
10. 高橋謙治 (30347447)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. WATANABE Masahiko (00182949)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 山崎勤 (80596148)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
13. 遠山将吾 (00388183)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
14. TAMURA Yutaka (50263174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Fujiwara Hiroyoshi (90381962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. YAGITA Kazuhiro (90324920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MORIHARA Toru (90336735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. KITABATAKE Yasuji (80506494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OHGITANI Eriko (80300820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. WATANABE Eri (20433253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SHIN-YA Masaharu (10405277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 森宏樹 (40388989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 中島利博 (90260752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 浅沼幹人 (00273970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 山川直樹 (20583040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 土田真嗣 (10719834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
27. 清水一憲 (70402500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 徳永大作 (90343409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
29. 相良亜木子 (10767916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 沢田光思郎 (40460555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. 大橋鈴世 (50440889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 三上靖夫 (80360030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
33. 山本健太 (00636160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. NISHIOKA Keisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. SAKAI Ryo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 甲斐広文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Arai Yuji 新井 祐志

ARAI Yuji 新井 祐志

NAKAMURA Naoto 中村 直登

TAKAHASHI Kenji 高橋 謙治

新井 佑志

新井 祐志 アライ ユウジ

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Establishment of a new exercise therapy for osteoarthritis using HIF-1alpha regulation by hypoxiaPrincipal Investigator

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Development of HIF-1a-induced exercise therapy focusing on the intra-articular hypoxic environmentPrincipal Investigator

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Arai Yuji 新井祐志

ARAI Yuji 新井祐志

NAKAMURA Naoto 中村直登

TAKAHASHI Kenji 高橋謙治

新井佑志

新井祐志アライユウジ