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TAKASAWA KUMI  高澤 久美

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… Alternative Names

Takasawa Kumi  高澤 久美

高澤 久美  タカサワ クミ

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Researcher Number 50359709
Affiliation (Current) 2022: 札幌医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2019 – 2020: 札幌医科大学, 医学部, 助教
2018: 札幌医科大学, 医学部, 研究員
2005: 富山大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 49020:Human pathology-related
Except Principal Investigator
Cerebral neurosurgery
Keywords
Principal Investigator
タイト結合 / クローディン18 / がん微小環境 / クローディン18 / クローディン / 胆管癌 / LSR / がん代謝
Except Principal Investigator
promoter / Rhodopsin … More / プロモーター / 緑色蛍光蛋白質 / 網膜 / 松果体 / ニューロン / 光受容 / トレーサー / Rhodosin / 蛍光蛋白質 / 神経回路 / 神経細胞 / アデノウィルス / 遺伝子導入 / 逆行性軸索輸送 / 投射ニューロン / 機能マッピング / rhodopsin / EGFP / retina / pineal body / neuron / photoreceptor / tracer Less
  • Research Projects

    (3 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (12 People)
  •  LSRが担うがん代謝リプログラミングと細胞間接着制御の分子機構Principal Investigator

    • Principal Investigator
      高澤 久美
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Sapporo Medical University
  •  Claudin-18 and tumor microenvironmentPrincipal Investigator

    • Principal Investigator
      Takasawa Kumi
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Sapporo Medical University
  •  Basicresearch for visualization of functional neuronal tract by gene transfer into CNS neurons

    • Principal Investigator
      KATO Ichiro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      University of Toyama

All 2021 2020 2019 2018 2008 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] A systemic apolipoprotein A-IV-associated amyloidosis confirmed by proteome analysis.2021

    • Author(s)
      Murakami T, Takasawa A, Moriki A, Igaki Y, Ikeda H, Murase K, Takada K, Magara K, Aoyama T, Ono Y, Kyuno D, Takasawa K, Murata M, Osanai M.
    • Journal Title

      Virchows Archiv

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16196
  • [Journal Article] Aberrant expression of junctional adhesion molecule‐A contributes to the malignancy of cervical adenocarcinoma by interaction with poliovirus receptor/CD1552021

    • Author(s)
      Murakami T, Takasawa A, Takasawa K, Akimoto T, Aoyama T, Magara K, Saito Y, Ota M, Kyuno D, Yamamoto S, Hasegawa T, Saito T, Osanai M.
    • Journal Title

      Cancer Sci.

      Volume: 112 Pages: 906-917

    • DOI

      10.1111/cas.14734

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-19K16561, KAKENHI-PROJECT-20K16196
  • [Journal Article] Aldolase A promotes epithelial‐mesenchymal transition to increase malignant potentials of cervical adenocarcinoma2020

    • Author(s)
      Saito Y, Takasawa A, Takasawa K, Aoyama T, Akimoto T, Ota M, Magara K, Murata M, Hirohashi H, Hasegawa T, Sawada N, Saito T, Osanai M.
    • Journal Title

      Cancer Sci.

      Volume: 111 Pages: 3071-3081

    • DOI

      10.1111/cas.14524

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-19K16561, KAKENHI-PROJECT-20K16196
  • [Journal Article] Identification of Coiled-Coil Domain?Containing Protein 180 and Leucine-Rich Repeat?Containing Protein 4 as Potential Immunohistochemical Markers for Liposarcoma Based on Proteomic Analysis Using Formalin-Fixed, Paraffin-Embedded Tissue2019

    • Author(s)
      Aoyama T, Takasawa A, Takasawa K, Ono Y, Emori M, Murata M, Hayasaka T, Fujitani N, Osanai M, Yamashita T, Hasegawa T, Sawada N.
    • Journal Title

      The American Journal of Pathology

      Volume: in press Pages: 1015-1028

    • DOI

      10.1016/j.ajpath.2019.01.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-18K15084, KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-18K09112, KAKENHI-PROJECT-19K16561, KAKENHI-PROJECT-19K16588, KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K10974
  • [Journal Article] Elevated expression of G protein-coupled receptor 30 (GPR30) is associated with poor prognosis in patients with uterine cervical adenocarcinoma.2019

    • Author(s)
      Ino Y, Akimoto T, Takasawa A, Takasawa K, Aoyama T, Ueda A, Ota M, Magara K, Tagami Y, Murata M, Hasegawa T, Saito T, Sawada N, Osanai M.
    • Journal Title

      Histology and Histopathology

      Volume: - Pages: 18157-18157

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15084
  • [Journal Article] Occludin induces microvillus formation via phosphorylation of ezrin in a mouse hepatic cell line.2018

    • Author(s)
      Ueda A, Takasawa A, Akimoto T, Takasawa K, Aoyama T, Ino Y, Nojima M, Ono Y, Murata M, Osanai M, Hasegawa T, Saito T, Sawada N.
    • Journal Title

      Exp Cell Res.

      Volume: 12(8) Pages: 172-180

    • DOI

      10.1016/j.yexcr.2018.03.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-16K21250, KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-18K15084
  • [Journal Article] Retinoic acid-metabolizing enzyme cytochrome P450 26A1 promotes skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene.2018

    • Author(s)
      Osanai M, Takasawa A, Takasawa K, Murata M, Sawada N
    • Journal Title

      Oncol Lett.

      Volume: 15 Pages: 9987-9993

    • DOI

      10.3892/ol.2018.8599

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-18K15084, KAKENHI-PROJECT-16K08693
  • [Journal Article] Estrogen/GPR30 Signaling Contributes to the Malignant Potentials of ER-Negative Cervical Adenocarcinoma via Regulation of Claudin-1 Expression.2018

    • Author(s)
      Akimoto T, Takasawa A, Takasawa K, Aoyama T, Murata M, Osanai M, Saito T, Sawada N
    • Journal Title

      Neoplasia

      Volume: 10 Pages: 1083-1093

    • DOI

      10.1016/j.neo.2018.08.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-18K15084, KAKENHI-PROJECT-16K08693
  • [Journal Article] Novel transcript profiling of diffuse alveolar damage induced by hyperoxia exposure in mice: normalization by glyceraldehyde 3-phosphate dehydrogenase2008

    • Author(s)
      Shimada, I, Matsui, K, Brinkmann, B, Hohoff, C, Hiraga, K, Tabuchi, Y, Takasaki, I, Kato, I, Kawaguchi, H, Takasawa, K, Iids, R, Takizawa, H, Matsuki, T
    • Journal Title

      Int. J. Legal Med (掲載確定)

    • NAID

      120001296353

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Journal Article] A novel model of insulin-dependent diabetes with renal and retinal lesions by transgenic expression of CaMKII a(Thr286Asp) in pancreatic 8 -cells2008

    • Author(s)
      Kato, I Oya, T, Suzuki, H, Takasawa, K, Ichsan, AM, Nakada, S, Ishii, Y, Shimada, Y, Sasahara, M, Tobe, S, Takasawa, S, Okamoto, H, Hiraga, K
    • Journal Title

      Diabetes Metab. Res. Rev (掲載確定)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Journal Article] CD38 is critical for social behaviour by regulating oxytocin secretion2007

    • Author(s)
      Jin, D, Liu, H-X, Hirai, H, Torashima, T, Nagai, T, Lopatina, O, Shnayder, N A, Yamada, K, Noda, M, Seike, T, Fujita, K, Takasawa, S, Yokoyama, S, Koizumi, K, Shiraishi, Y, Tanaka, S, Hashii, M, Yoshihara, T, Higashida, K, Islam, MS, Yamada, N, Hayashi, K, Noguchi, N, Kato, I, Okamoto, H, Matsushima, A, Salmina, A, Munesue, T, Shimizu, N, Mochida, S, Asano, M., Higashida, H
    • Journal Title

      Nature 446

      Pages: 41-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Journal Article] The galectin-3 gene promoter binding proteins in the liver of rats 48-h post-treatment with CCl(4)2006

    • Author(s)
      Li, F, Kato, I, Kawaguchi, H, Takasawa, K, Hibino, Y, Hiraea, K
    • Journal Title

      Gene 367

      Pages: 46-55

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Journal Article] RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low molecular weight heparin2006

    • Author(s)
      Myint, KM, Yamamoto, Y, Doi, T, Kato, I, Harashima, A, Yonekura, H, Watanabe, T, Shinohara, H, Takeuchi, M, Tsuneyama, K, Hashimoto, N, Asano, M, Takasawa, S, Okamoto, H, Yamamoto, H
    • Journal Title

      Diabetes 55

      Pages: 2510-2522

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Presentation] Aberrant expression of ALDOA contributes to malignant potentials of uterine cervical adenocarcinoma2020

    • Author(s)
      高澤 啓、高澤 久美、及能 大輔、小山内 誠
    • Organizer
      第79回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K16196
  • [Presentation] Role of claudin-1 in tight junction-associated function in cervical adenocarcinoma cells2020

    • Author(s)
      高澤 久美、高澤 啓、青山 智志、北嶋 洋志、及能 大輔、小野 祐輔、小山内 誠
    • Organizer
      第43回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K16196
  • [Presentation] Significance of claudin-18 and EGFR/ERK signaling in bile duct cancer.2019

    • Author(s)
      高澤久美、高澤啓、青山智志、小野祐輔、小山内誠
    • Organizer
      第42回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K15084
  • [Presentation] Role of claudin-18 on malignant potentials of bile duct cancer.2019

    • Author(s)
      Kumi Takasawa, Akira Takasawa, Makoto Osanai
    • Organizer
      Eleventh AACR-JCA Joint Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15084
  • [Presentation] Significance of estrogen/GPR30 signaling and claudin-1 in cervical adenocarcinoma2019

    • Author(s)
      Kumi Takasawa, Akira Takasawa, Taishi Akimoto, Tomoyuki Aoyama, Yusuke Ono, Tsuyoshi Saito, Makoto Osanai
    • Organizer
      The 38th Sapporo International Cancer Seminar
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15084
  • [Presentation] Overexpression of claudin-18 contributes to malignant potentials of bile duct cancer2018

    • Author(s)
      高澤久美、高澤啓、小山内誠、青山智志、小野祐輔、村田雅樹、澤田典均
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-18K15084
  • [Presentation] CaMKII alpha-transgenic mice shows pathological changes of diabetic nephropathy with enhanced expression of PDGF-B chain and PDGF-beta receptor2007

    • Author(s)
      Suzuki, H., Oya, T., Usui, I., Kato, I., Yamazaki, Y., Fujisaka, S., Bukhari, A. Asamizu, S., Kanatani, Y., Ihiki, M., Urakaze, M., Takasawa, S., Okamoto, H., Sasahara, M., Kobayashi, M
    • Organizer
      American Diabetes Association
    • Place of Presentation
      Chicago
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Presentation] Roles of advanced glycation endproducts and their receptor in diabetes-induced kidney injury2006

    • Author(s)
      Yamamoto, Y., Myint, K. M., Harashima, A. Takeuchi, A. Yonekura, H., Watanabe, T., Kato, I., Takasawa, S., Okamoto, H., Yamamoto, H
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Presentation] A novel model for diabetic retinopathy2006

    • Author(s)
      Ichsan, A. M., Kato, I., Oya, T., Tomi, M., Takasawa, S., Okamoto, H., Sasahara, M., Hayasaka S., Hosoya K., Hiraga, K
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Presentation] Embryonic lethality caused by targeted disruption of the mouse gene encoding a hydrogen carrier protein(H-protein), a component of the glycine cleavage system2006

    • Author(s)
      Kato, I., Takasawa, K., Kawaguchi, H., Mohafez, O., Nakada, S., Hiraga, K
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Presentation] Transgenic mice overexpressing mutant form of CaM kinase II(Thr286ASP) in pancreatic beta cells as a model for diabetic nephropathy2006

    • Author(s)
      Nakada, S., Kato, I., Takasaki, I., Tabuchi, Y., Shimada, Y., Hiraga, K., Takasawa, S., Okamoto, H
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Presentation] Roles of galectin-3 induced in the chemically injured hepatocytes in rodent2006

    • Author(s)
      Hiraga, K., Kawaguchi, H., Kato, I., Takasawa, K., Hsu, D. K., Liu, F-T
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Presentation] FENIB発症型ニューロセルピンを神経細胞内に蓄積するトランスジェニックマウスにおける易痙攣性の出現.2005

    • Author(s)
      高澤久美
    • Organizer
      第78回日本生化学会大会
    • Place of Presentation
      神戸
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Presentation] Transgenic mice expressing mutant G392E human neuroserpin show neuronal dysfunction with aggregate formation in neurons.2005

    • Author(s)
      高澤久美
    • Organizer
      第48回日本神経化学会大会
    • Place of Presentation
      福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • [Presentation] ヒト変異型ニューロセルピンをThy1.2プロモーター制御下で発現するマウスの中枢神経系障害.2005

    • Author(s)
      高澤久美
    • Organizer
      日本生化学会北陸支部第23回大会
    • Place of Presentation
      富山
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390396
  • 1.  KATO Ichiro (50250741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 2.  ENDO Shunro (70125269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  HAYASHI Nakamasa (50283073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  HIRAGA Koichi (40004733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 5.  上山 浩永 (70313608)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MURATA Masaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 7.  AKIMOTO TAISHI
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  OSANAI Makoto
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 9.  TAKASAWA Akira
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 10.  沢田 典均
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 11.  青山 智志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 12.  江森 誠人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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