Hirohashi Yoshihiko 廣橋良彦

… Alternative Names

Researcher Number	30516901
External Links
Affiliation (Current)	2020: 札幌医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2020: 札幌医科大学, 医学部, 准教授 2014 – 2015: 札幌医科大学, 医学部, 講師 2009 – 2014: 札幌医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Human pathology / Experimental pathology / Basic Section 49020:Human pathology-related Except Principal Investigator Human pathology / Basic Section 55010:General surgery and pediatric surgery-related / General surgery / Urology
Keywords	Principal Investigator がん幹細胞 / 免疫療法 / がん精巣抗原 / OR7C1 / がん抗原 / DNAJB8 / 大腸がん / 腫瘍抗原 / 抗原分子 / 班精巣抗原 … More Except Principal Investigator 分子病理 / CTL / がん幹細胞 / Cancer stem cell / がん免疫療法 / 幹細胞 / 免疫 / 癌幹細胞 / 腫瘍抗原 / 癌免疫 / 分子標的 / SP法 / CSC/CIC / CSC / CIC / がん抗原 / がんワクチン / CEP55 / DNAJB8 / OR7C1 / Survivin / ペプチド / 細胞障害性T細胞 / CTLエピトープ / がん / 抗原 / T細胞 / 癌 / 膵 / side population / 尿路上皮癌 / 化学療法 / 骨髄由来抑制細胞 / 免疫療法 / フローサイトメトリー / 腫瘍微小環境 / T細胞抗原受容体 / 免疫組織染色 / バイオマーカー / がん最適化治療 / 単細胞遺伝子解析 / がん組織微小環境 / がん免疫応答 / 単細胞遺伝子発現解析 / 免疫病理バイオマーカー / Tumor microenvironment / Single cell analysis / Tumor immune escape / Immune response / Immunohistochemistry / 腫瘍免疫 / 免疫病理診断 / Tumor antigen / 病理学 / 腫瘍学 / 免疫学 / 分子生物学 / 細胞・組織 / breast cancer / 免疫関与う / リンパ節転移 / 乳癌 / リンパ球 / cytotoxic T-cell Less

Single cell analysis of tumor-microenvironment based on TIL functionsPrincipal InvestigatorOngoing
- Principal Investigator
  
  廣橋良彦
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Sapporo Medical University
development of combined immunotherapy targeting ero1 in triple negative breast cancerOngoing
- Principal Investigator
  
  九冨五郎
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Sapporo Medical University
乳癌の転移巣を伴うリンパ節内のT-cellにおける免疫応答Ongoing
- Principal Investigator
  
  島宏彰
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Sapporo Medical University
Basic research on the immunohistological categorization of tumor microenvironment
- Principal Investigator
  
  TORIGOE Toshihiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Human pathology
- Research Institution
  Sapporo Medical University
Establishment of novel chemoimmunotherapy for urothelial cancer
- Principal Investigator
  
  Kitamura Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Toyama
Immunological aspects of cancer stem cell and spermatogenesisPrincipal Investigator
- Principal Investigator
  
  HIROHASHI Yoshihiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Sapporo Medical University
Immunological analysis of treatment resistant cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  HIROHASHI Yoshihiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Sapporo Medical University
Developing a novel vaccine therapy targeting cancer stem cells
- Principal Investigator
  
  HIRATA Koichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Sapporo Medical University
Molecular immunopathology of human cancer stem cell
- Principal Investigator
  
  SATO Noriyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Human pathology
- Research Institution
  Sapporo Medical University
Basic studies for the immune responses against cancer stem cells of sold tumors
- Principal Investigator
  
  TORIGOE Toshihiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Sapporo Medical University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

[Book] がん免疫療法の標的抗原、がん免疫療法-実用化へのチャレンジ-2010
- Author(s)
  守田玲菜、廣橋良彦、鳥越俊彦、佐藤昇志
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-21590401
[Book] Cancer, Immunology and Photonics S cience. Optical Devices and Systems, Biomedical and Green Technologies.2010
- Author(s)
  Noriyuki Sato, Yoshihiko Hirohashi, Tomohide Tsukahara, Shingo Ichimiya, Yasuaki Tamura and Toshihiko Torigoe
- Data Source
  KAKENHI-PROJECT-21590401
[Book] Cancer, Immunology and Photonics Science. Optical Devices and Systems, Biomedical and Green Technologies2010
- Author(s)
  Noriyuki Sato, Yoshihiko Hirohashi, Tomohide Tsukahara, Shingo Ichimiya, Yasuaki Tamura and Toshihiko Torigoe
- Data Source
  KAKENHI-PROJECT-21249025
[Book] バイオ医薬の開発技術とシーズ.第30章がんペプチド免疫治療2009
- Author(s)
  佐藤昇志、廣橋良彦、塚原智英、田村保明、一宮慎吾、鳥越俊彦
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] Differential bronchial epithelial response regulated by ΔNp63: a functional understanding of the epithelial shedding found in asthma.2019
- Author(s)
  Kubo Terufumi、Tsujiwaki Mitsuhiro、Hirohashi Yoshihiko、Tsukahara Tomohide、Kanaseki Takayuki、Nakatsugawa Munehide、Hasegawa Tadashi、Torigoe Toshihiko
- Journal Title
  
  Laboratory Investigation
  
  Volume: 99 Pages: 158-168
- DOI
  10.1038/s41374-018-0132-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-16K21249, KAKENHI-PROJECT-17H01540
[Journal Article] Clonal analysis revealed functional heterogeneity in cancer stem-like cell phenotypes in uterine endometrioid adenocarcinoma2019
- Author(s)
  Tabuchi Y, Hirohashi Y, Hashimoto S, Mariya T, Asano T, Ikeo K, Kuroda T, Mizuuchi M, Murai A, Uno S, Kawai N, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Saito T, Torigoe T.
- Journal Title
  
  Experimental and Molecular Pathology
  
  Volume: 106 Pages: 78-88
- DOI
  10.1016/j.yexmp.2018.11.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11285, KAKENHI-PLANNED-17H06399, KAKENHI-PROJECT-16H05451, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H01540
[Journal Article] Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine2018
- Author(s)
  Shima H, Kutomi G, Satomi F, Imamura M, Kimura Y, Mizuguchi T, Watanabe K, Takahashi A, Murai A, Tsukahara T, Kanaseki T, Hirohashi Y, Iwayama Y, Tsuruma T, Kameshima H, Sato N, Torigoe T, Takemasa I.
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 67 Pages: 1603-1609
- DOI
  10.1007/s00262-018-2217-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10672, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-17H01540
[Journal Article] Influence of PD-L1 expression in immune cells on the response to radiation therapy in patients with oropharyngeal squamous cell carcinoma.2018
- Author(s)
  Fukushima Yuki、Someya Masanori、Nakata Kensei、Hori Masakazu、Kitagawa Mio、Hasegawa Tomokazu、Tsuchiya Takaaki、Gocho Toshio、Ikeda Hikaru、Hirohashi Yoshihiko、Torigoe Toshihiko、Sugita Shintaro、Hasegawa Tadashi、Himi Tetsuo、Sakata Koh-ichi
- Journal Title
  
  Radiotherapy and Oncology
  
  Volume: 129 Pages: 409-414
- DOI
  10.1016/j.radonc.2018.08.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07760, KAKENHI-PROJECT-18K15555, KAKENHI-PROJECT-17K16466, KAKENHI-PROJECT-17H01540
[Journal Article] Cellular stress induces cancer stem-like cells through expression of DNAJB8 by activation of heat shock factor 12018
- Author(s)
  Kusumoto Hiroki、Hirohashi Yoshihiko、Nishizawa Satoshi、Yamashita Masamichi、Yasuda Kazuyo、Murai Aiko、Takaya Akari、Mori Takashi、Kubo Terufumi、Nakatsugawa Munehide、Kanaseki Takayuki、Tsukahara Tomohide、Kondo Toru、Sato Noriyuki、Hara Isao、Torigoe Toshihiko
- Journal Title
  
  Cancer Science
  
  Volume: 109 Pages: 741-750
- DOI
  10.1111/cas.13501
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-15K10606, KAKENHI-PROJECT-17H01540
[Journal Article] Development of a T-cell receptor multimer with high avidity for detecting a naturally presented tumor-associated antigen on osteosarcoma cells2018
- Author(s)
  Watanabe Kazue、Tsukahara Tomohide、Toji Shingo、Saitoh Shogo、Hirohashi Yoshihiko、Nakatsugawa Munehide、Kubo Terufumi、Kanaseki Takayuki、Kameshima Hidekazu、Terui Takeshi、Sato Noriyuki、Torigoe Toshihiko
- Journal Title
  
  Cancer Science
  
  Volume: 110 Pages: 40-51
- DOI
  10.1111/cas.13854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-17H01540
[Journal Article] The Antigen ASB4 on Cancer Stem Cells Serves as a Target for CTL Immunotherapy of Colorectal Cancer2018
- Author(s)
  Miyamoto Sho、Kochin Vitaly、Kanaseki Takayuki、Hongo Ayumi、Tokita Serina、Kikuchi Yasuhiro、Takaya Akari、Hirohashi Yoshihiko、Tsukahara Tomohide、Terui Takeshi、Ishitani Kunihiko、Hata Fumitake、Takemasa Ichiro、Miyazaki Akihiro、Hiratsuka Hiroyoshi、Sato Noriyuki、Torigoe Toshihiko
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 6 Pages: 358-369
- DOI
  10.1158/2326-6066.cir-17-0518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11729, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-17H01540
[Journal Article] Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy2017
- Author(s)
  Horibe, R. Hirohashi, Y. Asano, T. Mariya, T. Suzuki, T. Takaya, A. Saijo, H. Shionoya, Y. Kubo, T. Nakatsugawa, M. Kanaseki, T. Tsukahara, T. Watanabe, K. Atsuyama, E. Toji, S. Hirano, H. Hasegawa, T. Takahashi, H. Sato, N. Torigoe, T.
- Journal Title
  
  PLoS One
  
  Volume: 12 Pages: 0171460-0171460
- DOI
  10.1371/journal.pone.0171460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01540
[Journal Article] ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway2017
- Author(s)
  Ogawa T, Hirohashi Y, Murai A, Nishidate T, Okita K, Wang L, Ikehara Y, Satoyoshi T, Usui A, Kubo T, Nakastugawa M, Kanaseki T, Tsukahara T, Kutomi G, Furuhata T, Hirata K, Sato N, Mizuguchi T, Takemasa I, Torigoe T.
- Journal Title
  
  Oncotartget
  
  Volume: 8 Pages: 112550-112564
- DOI
  10.18632/oncotarget.22545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10672, KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-15K08413, KAKENHI-PROJECT-26462013
[Journal Article] Induction and Analysis of Cytotoxic T-Lymphocytes that Recognize Autologous Oral Squamous Cell Carcinoma2017
- Author(s)
  Okamoto, J. Y. Miyazaki, A. Kobayashi, J. I. Miyamoto, S. Sasaki, T. Kanaseki, T. Hirohashi, Y. Torigoe, T. Hiratsuka, H.
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Pages: 4889-4897
- DOI
  10.21873/anticanres.11898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01540
[Journal Article] Identification of antigenic peptides from novel renal cancer stem-like cell antigen, DNAJB8.2017
- Author(s)
  Nishizawa S, Hirohashi Y, Kusumoto H, Wakamiya T, Iguchi T, Yamashita S, Iba A, Kikkawa K, Kohjimoto Y, Torigoe T, Hara I
- Journal Title
  
  Biochemical Biophysical Research Communication
  
  Volume: 494 Pages: 693-699
- DOI
  10.1016/j.bbrc.2017.10.146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10606, KAKENHI-PROJECT-17K16811, KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-17H01540
[Journal Article] Cancer-associated oxidoreductase ERO1-alpha promotes immune escape through up-regulation of PD-L1 in human breast cancer2017
- Author(s)
  Tanaka T, Kutomi G, Kajiwara T, Kukita K, Kochin V, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Okamoto Y, Hirata K, Sato N, Tamura Y.
- Journal Title
  
  Oncotarget
  
  Volume: 2016 Pages: 24706-24718
- DOI
  10.18632/oncotarget.14960
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-17H01540
[Journal Article] Identification of cancer-stem cell antigens and development of CTL-mediated cancer immunotherapy2017
- Author(s)
  Miyamoto, S. Kanaseki, T. Hirohashi, Y. Tsukahara, T. Kikuchi, Y. Sato, N. Torigoe, T.
- Journal Title
  
  Japanese Journal of Clinical Immunology
  
  Volume: 40 Issue: 1 Pages: 40-47
- DOI
  10.2177/jsci.40.40
- NAID
  130005665568
- ISSN
  0911-4300, 1349-7413
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-17H01540
[Journal Article] HLA-A24 ligandome analysis of colon and lung cancer cells identifies a novel cancer-testis antigen and a neoantigen that elicits specific and strong CTL responses2017
- Author(s)
  Kochin V, Kanaseki T, Tokita S, Miyamoto S, Shionoya Yo, Kikuchi Y, Morooka D, Hirohashi Y, Tsukahara T, Watanabe K, Toji S, Kokai Y, Sato N, Torigoe T.
- Journal Title
  
  Oncoimmunology
  
  Volume: 6 Pages: 1-12
- DOI
  10.1080/2162402x.2017.1293214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08743, KAKENHI-PROJECT-17H01540
[Journal Article] Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen-specific CTL recognition2017
- Author(s)
  Yosuke Shionoya, Takayuki Kanaseki, Sho Miyamoto, et al.
- Journal Title
  
  Oncoimmunology
  
  Volume: 6 Pages: 1274476-1274476
- DOI
  10.1080/2162402x.2016.1274476
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460581, KAKENHI-PROJECT-17H01540
[Journal Article] GRIK2 has a role in the maintenance of urothelial carcinoma stem-like cells, and its expression is associated with poorer prognosis2017
- Author(s)
  Inoue Ryuta、Hirohashi Yoshihiko、Kitamura Hiroshi、Nishida Sachiyo、Murai Aiko、Takaya Akari、Yamamoto Eri、Matsuki Masahiro、Tanaka Toshiaki、Kubo Terufumi、Nakatsugawa Munehide、Kanaseki Takayuki、Tsukahara Tomohide、Sato Noriyuki、Masumori Naoya、Torigoe Toshihiko
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 28826-28839
- DOI
  10.18632/oncotarget.16259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10599, KAKENHI-PROJECT-17H01540
[Journal Article] LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells2017
- Author(s)
  Wang, L. Hirohashi, Y. Ogawa, T. Shen, M. Takeda, R. Murai, A. Yamamoto, E. Kubo, T. Nakatsugawa, M. Kanaseki, T. Tsukahara, T. Nishidate, T. Okita, K. Kutomi, G. Sato, N. Takemasa, I. Torigoe, T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 486 Pages: 232-238
- DOI
  10.1016/j.bbrc.2017.02.112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01540
[Journal Article] Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells2017
- Author(s)
  Takeda, R. Hirohashi, Y. Shen, M. Wang, L. Ogawa, T. Murai, A. Yamamoto, E. Kubo, T. Nakatsugawa, M. Kanaseki, T. Tsukahara, T. Nishidate, T. Okita, K. Kutomi, G. Sato, N. Takemasa, I. Torigoe, T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 485 Pages: 651-657
- DOI
  10.1016/j.bbrc.2017.02.081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01540
[Journal Article] Comprehensive single-cell transcriptome analysis reveals heterogeneity in endometrioid adenocarcinoma tissues2017
- Author(s)
  Hashimoto S, Tabuchi Y, Yurino H, Hirohashi Y, Deshimaru S, Asano T, Mariya T, Oshima K, Takamura Y, Ukita Y, Ametani A, Kondo N, Monma N, Takeda T, Misu S, Okayama T, Ikeo K, Saito T, Kaneko S, Suzuki Y, Hattori M, Matsushima K, et al.
- Journal Title
  
  Scientific Rep.
  
  Volume: 7 Pages: 14225-14225
- DOI
  10.1038/s41598-017-14676-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19546, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H01540
[Journal Article] Mismatch Repair Protein Deficiency Is a Risk Factor for Aberrant Expression of HLA Class I Molecules: A Putative "Adaptive Immune Escape" Phenomenon2017
- Author(s)
  Kubo, T. Hirohashi, Y. Matsuo, K. Sonoda, T. Sakamoto, H. Furumura, K. Tsukahara, T. Kanaseki, T. Nakatsugawa, M. Hirano, H. Furuhata, T. Takemasa, I. Hasegawa, T. Torigoe, T.
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Pages: 1289-1295
- DOI
  10.21873/anticanres.11446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01540
[Journal Article] Implication of chemo-resistant memory T cells for immune surveillance in patients with sarcoma receiving chemotherapy2017
- Author(s)
  Shibayama Y, Tsukahara T, Emori M, Murata K, Mizushima E, Hirohashi Y, Kanaseki T, Nakatsugawa M, Kubo T, Yamashita T, Sato N, Torigoe T
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Pages: 1739-1745
- DOI
  10.1111/cas.13319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10974, KAKENHI-PROJECT-17H01540
[Journal Article] Phosphorylation of HSF1 at serine 326 residue is related to the maintenance of gynecologic cancer stem cells through expression of HSP272017
- Author(s)
  Yasuda, K. Hirohashi, Y. Mariya, T. Murai, A. Tabuchi, Y. Kuroda, T. Kusumoto, H. Takaya, A. Yamamoto, E. Kubo, T. Nakatsugawa, M. Kanaseki, T. Tsukahara, T. Tamura, Y. Hirano, H. Hasegawa, T. Saito, T. Sato, N. Torigoe, T.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 31540-31553
- DOI
  10.18632/oncotarget.16361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01540
[Journal Article] Matrix metalloproteinase-10 regulates stemness of ovarian cancer stem-like cells by activation of canonical Wnt signaling and can be a target of chemotherapy-resistant ovarian cancer.2016
- Author(s)
  Mariya T, Hirohashi Y, Torigoe T, Tabuchi Y, Asano T, Saijo H, Kuroda T, Yasuda K, Mizuuchi M, Saito T, Sato N
- Journal Title
  
  Oncotarget
  
  Volume: in press Pages: 1-17
- DOI
  10.18632/oncotarget.8645
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04722
[Journal Article] Olfactory Receptor Family 7 Subfamily C Member 1 Is a Novel Marker of Colon Cancer-Initiating Cells and Is a Potent Target of Immunotherapy.2016
- Author(s)
  Rena Morita, Yoshihiko Hirohashi, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 1;22(13) Pages: 3298-308
- DOI
  10.1158/1078-0432.ccr-15-1709
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-26461921, KAKENHI-PROJECT-26860239
[Journal Article] MAPK13 is preferentially expressed in gynecological cancer stem cells and has a role in the tumor-initiation.2016
- Author(s)
  Yasuda K, Hirohashi Y, Kuroda T, Takaya A, Kubo T, Kanaseki T, Tsukahara T, Hasegawa T, Saito T, Sato N, Torigoe T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 472 Pages: 643-647
- DOI
  10.1016/j.bbrc.2016.03.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04722
[Journal Article] Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480.2016
- Author(s)
  Akari Takaya, Yoshihiko Hirohashi, et al.
- Journal Title
  
  PLoS One
  
  Volume: 14;11(7)
- DOI
  10.1371/journal.pone.0158903
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-26860239
[Journal Article] Olfactory receptor family receptor, family 7, subfamily C, member 1 is a novel marker of colon cancer-initiating cells and is a potent target of immunotherapy.2016
- Author(s)
  Morita R, Hirohashi Y, Torigoe T, Inoda S, Takahashi A, Mariya T, Asanuma H, Tamura Y, Tsukahara T, Kanaseki T, Kubo T, Kutomi G, Mizuguchi T, Terui T, Ishitani K, Hashino S, Kondo T, Minagawa N, Takahashi N, Taketomi A, Todo S, Asaka M, Sato N.
- Journal Title
  
  Clin Cancer Res
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04722
[Journal Article] Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress.2016
- Author(s)
  Hiroshi Saijo, Yoshihiko Hirohashi, et al.
- Journal Title
  
  Oncotarget
  
  Volume: 2;7(31) Pages: 50043-50056
- DOI
  10.18632/oncotarget.10571
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-26460944
[Journal Article] Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is involved in cervical cancer stemness and can be a target of immunotherapy.2016
- Author(s)
  Asano T, Hirohashi Y, Torigoe T, Mariya T, Horibe R, Kuroda T, Tabuchi Y, Saijo H, Yasuda K, Mizuuchi M, Takahashi A, Asanuma H, Hasegawa T, Saito T, Sato N.
- Journal Title
  
  Oncotarget.
  
  Volume: 7 Pages: 11223-11237
- DOI
  10.18632/oncotarget.7165
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-25462599
[Journal Article] Immune responses to human cancer stem-like cells/cancer-initiating cells.2016
- Author(s)
  Hirohashi Y, Torigoe T, Tsukahara T, Kanaseki T, Kochin V, Sato N
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Pages: 12-17
- DOI
  10.1111/cas.12830
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04722
[Journal Article] Trials of vaccines for pancreatic ductal adenocarcinoma: Is there any hope of an improved prognosis?2015
- Author(s)
  Mizuguchi T, Torigoe T, Satomi F, Shima H, Kutomi G, Ota S, Ishii M, Hayashi H, Asakura S, Hirohashi Y, Meguro M, Kimura Y, Nishidate T, Okita K, Ishino M, Miyamoto A, Hatakenaka M, Sato N, Hirata K.
- Journal Title
  
  Surg Today
  
  Volume: in press
- DOI
  10.1007/s00595-015-1120-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659592
[Journal Article] Phase I Clinical Study of Survivin-Derived Peptide Vaccine for Patients with Advanced Gastrointestinal Cancers.2015
- Author(s)
  Satomi F, Shima H, Mizuguchi T, Torigoe T, Kutomi G, Kimura Y, Hirohashi Y, Tamura Y, Tsukahara T, Kanaseki T, Takahashi A, Asanuma H, Ito Y, Hayashi H, Sugita O, Sato N and Hirata K.
- Journal Title
  
  Int J Cancer Clin Res
  
  Volume: 2
- NAID
  40020774852
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659592
[Journal Article] Expression of hepatocyte growth factor in prostate cancer may indicate a biochemical recurrence after radical prostatectomy.2015
- Author(s)
  Nishida S, Hirohashi Y, Torigoe T, Nojima M, Inoue R, Kitamura H, Tanaka T, Asanuma H, Sato N, Masumori N.
- Journal Title
  
  Anticancer Res
  
  Volume: 35 Pages: 413-8
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590449
[Journal Article] Expression of hepatocyte growth factor in prostate cancer may indicate a biochemical recurrence after radical prostatectomy.2015
- Author(s)
  Nishida S, Hirohashi Y, Torigoe T., Nojima M, Inoue R, Kitamura H, Tanaka T, Asanuma H, Sato N, Masumori N.
- Journal Title
  
  Anticancer Res
  
  Volume: 35 Pages: 413-418
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659592
[Journal Article] Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells.2014
- Author(s)
  Morita R, Nishizawa S, Torigoe T, Takahashi A, Tamura Y, Tsukahara T, Kanaseki T, Sokolovskaya A, Kochin V, Kondo T, Hashino S, Asaka M, Hara I, Hirohashi Y, Sato N.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Pages: 389-395
- DOI
  10.1111/cas.12362
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-25462344
[Journal Article] Prognostic impact of human leukocyte antigen class I expression and association of platinum resistance with immunologic profiles in epithelial ovarian cancer.2014
- Author(s)
  Mariya T, Hirohashi Y, Torigoe T, Asano T, Kuroda T, Yasuda K, Mizuuchi M, Sonoda T, Saito T, Sato N.
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 2 Pages: 1220-1229
- DOI
  10.1158/2326-6066.cir-14-0101
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165
[Journal Article] Prognostic impact of human leukocyte antigen class I expression and association of platinum resistance with immunologic profiles in epithelial ovarian cancer.2014
- Author(s)
  Mariya T, Hirohashi Y, Torigoe T., Asano T, Kuroda T, Yasuda K, Mizuuchi M, Sonoda T, Saito T, Sato N
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 2 Pages: 1220-1229
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659592
[Journal Article] Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity.2014
- Author(s)
  Yasuda K, Torigoe T, Mariya T, Asano T, Kuroda T, Matsuzaki J, Ikeda K, Yamauchi M, Emori M, Asanuma H, Hasegawa T, Saito T, Hirohashi Y, Sato N.
- Journal Title
  
  Lab Invest
  
  Volume: 94 Pages: 1355-1369
- DOI
  10.1038/labinvest.2014.122
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592
[Journal Article] Production of multiple CTL epitopes from multiple tumor-associated antigens.2014
- Author(s)
  Morita R, Hirohashi Y, Nakatsugawa M, Kanaseki T, Torigoe T, Sato N.
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1139 Pages: 345-355
- DOI
  10.1007/978-1-4939-0345-0_28
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165
[Journal Article] Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population.2013
- Author(s)
  Yasuda K, Torigoe T, Morita R, Kuroda T, Takahashi A, Matsuzaki J, Kochin V, Asanuma H, Hasegawa T, Saito T, Hirohashi Y, Sato N.
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0068187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467
[Journal Article] Ectopically expressed variant form of sperm mitochondria-associated cysteine-rich protein augments tumorigenicity of the stem cell population of lung adenocarcinoma cells.2013
- Author(s)
  Takahashi A, Hirohashi Y, Torigoe T, Tamura Y, Tsukahara T, Kanaseki T, Kochin V, Saijo H, Kubo T, Nakatsugawa M, Asanuma H, Hasegawa T, Kondo T, Sato N.
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0069095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-25462344
[Journal Article] Prostate cancer stem-like cells/cancer-initiating cells have an autocrine system of hepatocyte growth factor2013
- Author(s)
  Nishida S, Hirohashi Y, Torigoe T, Inoue R, Kitamura H, Tanaka T, Takahashi A, Asanuma H, Masumori N, Tsukamoto T, Sato N.
- Journal Title
  
  Cancer science
  
  Volume: 104 Pages: 431-436
- DOI
  10.1111/cas.12104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24592399, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-221S0001
[Journal Article] Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal2013
- Author(s)
  Michifuri Y, Hirohashi Y, Torigoe T, Miyazaki A, Fujino J, Tamura Y, Tsukahara T, Kanaseki T, Kobayashi J, Sasaki T, Takahashi A, Nakamori K, Yamaguchi A, Hiratsuka H, Sato N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 439 Pages: 96-102
- DOI
  10.1016/j.bbrc.2013.08.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659901, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-24792005, KAKENHI-PROJECT-25462344, KAKENHI-PROJECT-25463115
[Journal Article] Expression and function of FERMT genes in colon carcinoma cells2013
- Author(s)
  Kiriyama K, Hirohashi Y, Torigoe T, et al.
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 167-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590449
[Journal Article] Expression and function of FERMT genes in colon carcinoma cells.2013
- Author(s)
  Kiriyama K, Hirohashi Y, Torigoe T, Kubo T, Tamura Y, Kanaseki T, Takahashi A, Nakazawa E, Saka E, Ragnarsson C, Nakatsugawa M, Inoda S, Asanuma H, Takasu H, Hasegawa T, Yasoshima T, Hirata K, Sato N
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 167-73
- Data Source
  KAKENHI-PROJECT-24659592
[Journal Article] Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients.2013
- Author(s)
  Kameshima H, Tsuruma T, Kutomi G, Shima H, Iwayama Y, Kimura Y, Imamura M, Torigoe T, Takahashi A, Hirohashi Y, Tamura Y, Tsukahara T, Kanaseki T, Sato N, Hirata K
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 124-129
- DOI
  10.1111/cas.12046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592
[Journal Article] DNA methyltransferase 1 is essetial for initiation of the colon cancers.2013
- Author(s)
  Morita R,Hirohashi Y,Suzuki H, et al
- Journal Title
  
  Exp Mol Pathol.
  
  Volume: 94 Pages: 322-327
- DOI
  10.1016/j.yexmp.2012.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115
[Journal Article] Preferential expression of cancer/testis genes in cancer stem-like cells: proposal of a novel sub-category, cancer/testis/stem gene2013
- Author(s)
  Yamada R, Takahashi A, Torigoe T, Morita R, Tamura Y, Tsukahara T, Kanaseki T, Kubo T, Watarai K, Kondo T, Hirohashi Y, Sato N.
- Journal Title
  
  Tissue Antigens
  
  Volume: 81(6) Pages: 428-34
- DOI
  10.1111/tan.12113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467
[Journal Article] Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population2012
- Author(s)
  Mori T, Nishizawa S, Hirohashi Y, Torigoe T, Tamura Y, Takahashi A, Kochin V, Fujii R, Toru K, Greene MI, Hara I, Sato N.
- Journal Title
  
  Exp Mol Pathol
  
  Volume: 92 Pages: 27-32
- URL
  http://dx.doi.org/10.1016/j.yexmp.2011.09.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] Heat shock enhances the expression of cyctoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes2012
- Author(s)
  Takahashi A, Torigoe T, Tamura Y, Kanaseki T, Tsukahara T, Sasaki Y, Kameshima H, Tsuruma T, Hirata K, Tokino T, Hirohashi Y, Sato N
- Journal Title
  
  Cell Stress Chaperones.
  
  Volume: 17 Pages: 757-63
- DOI
  10.1007/s12192-012-0348-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-24791467
[Journal Article] Novel oligomannose liposome-DNA complex DNA vaccination efficiently evokes anti-HPV E6 and E7 CTL responses2012
- Author(s)
  Mizuuchi M, Hirohashi Y, Torigoe T, Takafumi K, Yasuda K, Saito T, Sato N.
- Journal Title
  
  Exp Mol Pathol
  
  Volume: 92 Pages: 185-190
- URL
  http://dx.doi.org/10.1016/j.yexmp.2011.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population2012
- Author(s)
  Mori T, Nishizawa S, Hirohashi Y, Torigoe T, Tamura Y, Takahashi A, Kochin V, Fujii R, Toru K, Greene MI, Hara I, Sato N
- Journal Title
  
  Exp Mol Pathol
  
  Volume: 92 Pages: 27-32
- URL
  http://dx.doi.org/10.1016/j.yexmp.2011.09.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] Establishment of a monoclonal anti-pan HLA class I antibody suitable for immunostaining of formalin-fixed tissue: Unusually high frequency of down-regulation in breast cancer tissues.2012
- Author(s)
  Torigoe, T., Asanuma, H., Nakazawa. E., Tamura, Y., Hirohashi, Y., Yamamoto, E., Kanaseki, T., Hasegawa, T., Sato, N.
- Journal Title
  
  Pathol Int.
  
  Volume: 62 Pages: 303-8
- DOI
  10.1111/j.1440-1827.2012.02789.x
- NAID
  10031185205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659592
[Journal Article] HSP DNAJB8 controls tumor-initiating ability in renal cancer-stem cells2012
- Author(s)
  Nishizawa, S., Mori, T., Hirohashi, Y., Torigoe, T., Tamura, Y., Kamiguchi, K., Takahashi, A., Kanaseki, T., Nakazawa, E., Asanuma, H., Sokolovskaya, A., Morita, R., Yamada, R., Fujii, R., Kondo, T., Hasegawa, T., Hara, I. and Sato, N.
- Journal Title
  
  Cancer Res,
  
  Volume: (in press) Pages: 2844-54
- DOI
  10.1158/0008-5472.can-11-3062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659165
[Journal Article] ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells.2012
- Author(s)
  Matsuzaki J,Torigoe T,Hirohashi Y, Kamiguchi K,Tamura Y, Tsukahara T,Kubo T, Takahashi A, Nakazawa E,Saka E, Yasuda K,Takahashi S,Sato N.
- Journal Title
  
  Carcinogenesis
  
  Volume: 33 Pages: 996-1003
- DOI
  10.1093/carcin/bgs118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06539, KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22689041, KAKENHI-PROJECT-23590427
[Journal Article] Novel oligomannose liposome-DNA complex DNA vaccination efficiently evokes anti-HPV E6 and E7 CTL responses2012
- Author(s)
  Mizuuchi M, Hirohashi Y, Torigoe T, Takafumi K, Yasuda K, Saito T, Sato N
- Journal Title
  
  Exp Mol Pathol
  
  Volume: 92 Pages: 185-190
- DOI
  10.1016/j.yexmp.2011.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-21592141
[Journal Article] Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population.2012
- Author(s)
  Takashi Mori, Satoshi Nishizawa, Yoshihiko Hirohashi, Toshihiko Torigoe, Yasuaki Tamura, Akari Takahashi, Vitaly Kochin, Reona Fujii, Kondo Toru, Mark I. Greene, Isao Hara, Noriyuki Sato
- Journal Title
  
  Exp Mol Pathol.
  
  Volume: 92 Pages: 27-32
- DOI
  10.1016/j.yexmp.2011.09.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10F00121, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659592
[Journal Article] Depletion of Tregs in vivo: a promising approach to enhance antitumor immunity without autoimmunity2012
- Author(s)
  Morita R,Hirohashi Y,Sato N.
- Journal Title
  
  Immunotherapy
  
  Volume: 4 Pages: 1103-1105
- DOI
  10.2217/imt.12.116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-24590449
[Journal Article] Cytotixic T lymphocytes efficiently recognize human colon cancer stem-like cells2011
- Author(s)
  Inoda, S., Hirohashi, Y., Torigoe, T., Takahashi, A., Morita, R., Nakatsugawa, M., Nishizawa, S., Tamura, Y., Tsuruma, T., Terui, T., Ishitani, K., Hirata, K. and Sato, N.
- Journal Title
  
  Am. J. Pathol
  
  Volume: 178 Pages: 1805-1813
- URL
  http://dx.doi.org/10.1016/j.ajpath.2011.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] Comparison of speedy PCR-SSP method and serological typing of HLA-A24 for Japanese cancer patients2011
- Author(s)
  Nakatsugawa M, Hirohashi Y, Torigoe T, Inoda S, Kiriyama K, Tamura Y, Sato E, Takahashi H, Sato N.
- Journal Title
  
  J Immunoassay Immunoch
  
  Volume: 32 Pages: 93-102
- DOI
  10.1080/15321819.2010.543219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-23590427
[Journal Article] Immunogenic enhancement and clinical effect by type-I interferon of anti-apoptotic protein, survivin- derived peptide vaccine, in advanced colorectal cancer patients2011
- Author(s)
  Kameshima, H., Tsuruma, T., Torigoe, T., Takahashi, A., Hirohashi, Y., Tamura, Y., Tsukahara, T., Ichimiya, S., Kanaseki, T., Iwayama, Y., Sato, N., Hirata, K.
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 1181-1187
- DOI
  10.1111/j.1349-7006.2011.01918.x
- NAID
  10029294487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-22689041, KAKENHI-PROJECT-23590405, KAKENHI-PROJECT-23590427
[Journal Article] A phase I clinical trial of surviving-derived peptide vaccine therapy in HLA-A24-positive patients with oral cancer2011
- Author(s)
  Miyazaki A, Kobayashi J, Torigoe T, Hirohashi Y, Yamamoto T, Yamaguchi A, Asanuma H, Takahashi A, Michifuri Y, Nakamori K, Nagai I, Sato N, Hiratsuka H.
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 324-329
- DOI
  10.1111/j.1349-7006.2010.01789.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22390388, KAKENHI-PROJECT-22592242, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235
[Journal Article] The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colo rectal carcinoma2011
- Author(s)
  Inoda S, Morita R, Hirohashi Y, Torigoe T, Asanuma H, Nakazawa E, Nakatsugawa M, Tamura Y, Kamiguchi K, Tsuruma T, Terui T, Ishitani K, Hashino S, Wang Q, Greene MI, Hasegawa T, Hirata K, Asaka M, Sato N.
- Journal Title
  
  Exp Mol Pathol
  
  Volume: 90 Pages: 55-60
- DOI
  10.1016/j.yexmp.2010.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659235
[Journal Article] Autoantibody against hypoxia-inducible factor prolylhydroxylase-3 is a potential serological markerfor renal cell carcinoma2011
- Author(s)
  Tanaka, T., Kitamura, H., Torigoe, T., Hirohashi, Y., Masumori, N., Sato, N. and Tsukamoto, T.
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 137 Pages: 789-784
- DOI
  10.1007/s00432-010-0940-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-22791477
[Journal Article] Tumor-Produced Secreted Form of Binding of Immunoglobulin Protein (BiP) elicits Antigen Specific Tumor Immunity2011
- Author(s)
  Tamura Y, Hirohashi Y, Kutomi G, Nakanishi K, Kamiguchi K, Torigoe T, Sato N.
- Journal Title
  
  J.Immunol
  
  Volume: 186 Pages: 4325-4230
- DOI
  10.4049/jimmunol.1004048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590400, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-23590427
[Journal Article] Tumor-associated dendritic cells : molecular mechanismsto suppress antitumor immunity2011
- Author(s)
  Hirohashi, Y. and Sato, N.
- Journal Title
  
  Immunotherapy
  
  Volume: 3 Pages: 945-947
- DOI
  10.2217/imt.11.94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235
[Journal Article] Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells2011
- Author(s)
  Inoda, S., Hirohashi, Y., Torigoe, T., Takahashi, A., Morita, R., Nakatsugawa, M., Nishizawa, S., Tamura, Y., Tsuruma, T., Terui, T., Ishitani, K., Hirata, K. and Sato, N.
- Journal Title
  
  Am. J. Pathol
  
  Volume: 178 Pages: 1805-1813
- DOI
  10.1016/j.ajpath.2011.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22390278, KAKENHI-PROJECT-23590427
[Journal Article] The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma2011
- Author(s)
  Inoda S, Morita R, Hirohashi Y, Torigoe T, Asanuma H, Nakazawa E, Nakatsugawa M, Tamura Y, Kamiguchi K, Tsuruma T, Terui T, Ishitani K, Hashino S, Wang Q, Greene MI, Hasegawa T, Hirata K, Asaka M, Sato N.
- Journal Title
  
  Exp. Mol. Pathol
  
  Volume: 90 Pages: 55-60
- URL
  http://dx.doi.org/10.1016/j.yexmp.2010.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity2011
- Author(s)
  Nakatsugawa, M., Takahashi, A., Hirohashi, Y., Torigoe, T., Inoda, S., Asanuma, H., Tamura, Y., Hasegawa, T., Takahashi, H., and Sato, N.
- Journal Title
  
  Lab Invest
  
  Volume: 91 Pages: 1796-1804
- DOI
  10.1038/labinvest.2011.140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-23590427
[Journal Article] Establishment of shared antigen reactive cytotoxic T lymphocyte using co-stimulatory molecule introduced autologous cancer cells2010
- Author(s)
  廣橋良彦, et al
- Journal Title
  
  Exp Mol Pathol. 88
  
  Pages: 128-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] Immune response against tumor antigens expressed on human cancer-stem cells/tumor-initiating cells.2010
- Author(s)
  Hirohashi Y., Torigoe T., et al.
- Journal Title
  
  Immunotherapy
  
  Volume: 2 Pages: 201-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells2010
- Author(s)
  Hirohashi, Y., Torigoe, T., Inoda, S., Takahashi, A., Morita, R., Nishizawa, S., Tamura, Y., Suzuki, H., Yoyota, M. Sato, N.
- Journal Title
  
  Immunotherapy
  
  Volume: 2 Pages: 201-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells2010
- Author(s)
  Hirohashi, Y., Torigoe, T., Inoda, S., Takahashi, A., Morita, R., Nishizawa, S., Tamura, Y., Suzuki, H., Yoyota, M. Sato, N.
- Journal Title
  
  Immunotherapy
  
  Volume: 2 Pages: 201-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] Establishment of shared antigen reactive cytotoxic T lymphocyte using co-stimulatory molecule introduced autologous cancer cells. Exp Mol Pathol.2010
- Author(s)
  Hirohashi, Y., Torigoe, T., et al.
- Journal Title
  
  Exp Mol Pathol.
  
  Volume: 88 Pages: 128-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] Immune response against tumor antigens expressed on human cancer-stem cells/tumor-initiating cells2010
- Author(s)
  廣橋良彦, et al
- Journal Title
  
  Immunotherapy 2
  
  Pages: 201-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells2010
- Author(s)
  Hirohashi, Y., et al
- Journal Title
  
  Immunotherapy 2
  
  Pages: 201-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells.2010
- Author(s)
  Hirohashi, Y., Sato, N., et al.
- Journal Title
  
  Immunotherapy
  
  Volume: 2 Pages: 201-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] がん幹細胞抗原の検索とがんワクチンへの応用2009
- Author(s)
  廣橋良彦, 他
- Journal Title
  
  最新医学 64
  
  Pages: 27-36
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] The functioning antigens ; beyond just as the immunologic targets2009
- Author(s)
  Hirohashi, Y., Torigoe, T., Inoda, S., Kobayashi, J., Nakatsugawa, M., Mori, T., Hara, I. and Sato, N.
- Journal Title
  
  Cancer Sci.
  
  Volume: 100 Pages: 798-806
- DOI
  10.1111/j.1349-7006.2009.01137.x
- NAID
  10025145179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
[Journal Article] Clonal diversity of cytotoxic T lymphocytes that recognize autologous oral squamous cell carcinoma2009
- Author(s)
  Kobayashi, J., Torigoe, T., Hirohashi, Y., Tamura, Y., Kamiguchi, K., Miyazaki, A., Yamaguchi, A., Yamamoto, T., Hariu, H., Hiratsuka, H. and Sato, N.
- Journal Title
  
  Hum Immunol.
  
  Volume: 70 Pages: 89-95
- URL
  http://dx.doi.org/10.1016/j.humimm.2008.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] A novel spliced form of a lens protein as a novel lung cancer antigen, Lengsin splicing variant 4.2009
- Author(s)
  Nakatsugawa, M. Hirohashi, Y., Torigoe, T., Asanuma, H., Takahashi, A., Inosa, S., Kiriyama, K., Nakazawa, E., Harada, K., Takasi, H., Tamura, Y., Kamiguchi, K., Shijubo, N., Honda, R., Nomura, N., Hasegawa, T., Takahashi, H. and Sato, N.
- Journal Title
  
  Cancer Sci.
  
  Volume: 100 Pages: 1485-1493
- DOI
  10.1111/j.1349-7006.2009.01187.x
- NAID
  10027193512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
[Journal Article] Establishment of shared antigen reactive cytotixic T lymphocytes using co-stimulatory molecule introduced autologous cancer cells2009
- Author(s)
  Hirohashi, Y., Torigoe, T., Hirai, I., Tamura, Y., Nakatsugawa, M., Inoue, Y., Kanaseki, T., Kamiguchi, K., Ikeda, H., Sasaki, A., Yamanaka, N. and Sato, N.
- Journal Title
  
  Exp. Mol. Pathol.
- URL
  http://dx.doi.org/10.1016/j.yexmp.2009.09.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] Phase I clinical study of anti-apoptosis protein survivin-derived peptide vaccination for patients with advanced or recurrent urothelial cancer2009
- Author(s)
  Honma, I., Kitamura, H., Torigoe, A. Takahashi, T., Tanaka, T., Sato, E., Hirohashi, Y., Masumori, N., Tsukamoto, T., Sato, N.
- Journal Title
  
  Cancer Immunol. Immunother.
  
  Volume: 58 Pages: 1801-1807
- DOI
  10.1007/s00262-009-0691-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
[Journal Article] Clonal diversity of cytotoxic T lymphocytes that recognize autologous oral squamous cell carcinoma2009
- Author(s)
  Kobayashi, J., Torigoe, T., Hirohashi, Y., Tamura, Y., Kamiguchi, K., Miyazaki, A., Yamaguchi, A., Yamamoto, T., Hariu, H., Hiratsuka, H. and Sato, N.
- Journal Title
  
  Hum Immunol
  
  Volume: 70 Pages: 89-95
- URL
  http://dx.doi.org/10.1016/j.humimm.2008.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] Establishment of shared antigen reactive cytotixic T lymphocytes using co-stimulatory molecule introduced autologous cancer cells2009
- Author(s)
  Hirohashi, Y., Torigoe, T., Hirai, I., Tamura, Y., Nakatsugawa, M., Inoue, Y., Kanaseki, T., Kamiguchi, K., Ikeda, H., Sasaki, A., Yamanaka, N. and Sato, N.
- Journal Title
  
  Exp. Mol. Pathol
- URL
  http://dx.doi.org/10.1016/j.yexmp.2009.09.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] The functioning antigens ; beyond just as the immunologic targets2009
- Author(s)
  廣橋良彦, et al
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 798-806
- NAID
  10025145179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] Molecular pathologic approaches to human tumor immunology2009
- Author(s)
  Sato, N., Hirohashi, Y., Tsukahara, T., Kikuchi, T., Sahara, H., Kamiguchi, K., Ichimiya, S., Tamura, H. and Torigoe, T.
- Journal Title
  
  Pathol. Int.
  
  Volume: 59 Pages: 205-217
- DOI
  10.1111/j.1440-1827.2009.02353.x
- NAID
  10027379604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
[Journal Article] Targeting to static endosome is required for efficient cross-presentation of endoplasmic reticulum-resident oxygen regulated protein 150(ORP150)-peptide complexes2009
- Author(s)
  Kutomi, G., Tamura, Y., Okuya, K., Hirohashi, Y., Kamiguchi, K., Saito, K., Torigoe, T., Ogawa, S., Hirata, K. and Sato, N.
- Journal Title
  
  J. Immunol.
  
  Volume: 183 Pages: 5861-5869
- DOI
  10.4049/jimmunol.0803768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
[Journal Article] Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from surviving and that from its splice variant surviving-2B in oral cancer patients2009
- Author(s)
  Kobayashi, J., Torigoe, T., Hirohashi, Y., Idenoue, S., Miyazaki, A., Yamaguchi, A., Hiratsuka, H. and Sato, N.
- Journal Title
  
  J. Transl. Med.
  
  Volume: 7 Pages: 1-11
- DOI
  10.1186/1479-5876-7-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
[Journal Article] The functioning antigens ; beyond just as the immunologic targets2009
- Author(s)
  Hirohashi, Y., et al
- Journal Title
  
  Cancer Sci 100
  
  Pages: 798-806
- NAID
  10025145179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma2009
- Author(s)
  Inoda, S., Hirohashi, Y., Torigoe, T., Nakatsugawa, M., Kiriyama, K., Harada, K., Takasu, H., Tamura, Y., Kamiguchi, K., Asanuma, H., Tsuruma, T., Terui, T., Ishitani, K., Ohmura, T., Hasegawa, T., Hirata, K. and Sato, N.
- Journal Title
  
  J. Immunother.
  
  Volume: 32 Pages: 474-485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma2009
- Author(s)
  Inoda, S., Hirohashi, Y., Torigoe, T., Nakatsugawa, M., Kiriyama, K., Harada, K., Takasu, H., Tamura, Y., Kamiguchi, K., Asanuma, H., Tsuruma, T., Terui, T., Ishitani, K., Ohmura, T., Hasegawa, T., Hirata, K. and Sato, N.
- Journal Title
  
  J. Immunother
  
  Volume: 32 Pages: 474-485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Journal Article] Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer2009
- Author(s)
  Honma, I., Torigoe, T., Hirohashi, Y., Kitamura, H., Sato, E., Masumori, N., Tamura, Y., Tsukamoto, T., Sato, N.
- Journal Title
  
  J. Transl. Med.
  
  Volume: 7 Pages: 103-110
- DOI
  10.1186/1479-5876-7-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
[Journal Article] Human leukocyte antigen class I down-regulation in muscle-invasive bladder cancer : Its association with clinical characteristics and survival after cystectomy2009
- Author(s)
  Homma, I., Kitamura, H., Torigoe, T., Tanaka, T., Sato, E., Hirohashi, Y., Masumori, N., Sato, N. and Tsukamoto, T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 100 Pages: 2331-2334
- DOI
  10.1111/j.1349-7006.2009.01329.x
- NAID
  10027198144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
[Journal Article] DNA methyltransferase 1 is essential for maintenance of human colon cancer stem-like cells
- Author(s)
  Morita, R., Hirohashi, Y., Torigoe, T., Takahashi, A., Saka, E., Asanuma, H., Suzuki, H., Tamura, H., Nakazawa, E., Ito-Inoda, S., Hashino, S., Hasegawa, T., Tokino, T., Toyota, M., Asaka, M. and Sato, N.
- Journal Title
  
  Am J. Pathol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590401
[Journal Article] DNA methyltransferase 1 is essential for maintenance of human colon cancer stem-like cells
- Author(s)
  Morita, R., Hirohashi, Y., Torigoe, T., Takahashi, A., Saka, E., Asanuma, H., Suzuki, H., Tamura, H., Nakazawa, E., Ito-Inoda, S., Hashino, S., Hasegawa, T., Tokino, T., Toyota, M., Asaka, M. and Sato, N.
- Journal Title
  
  Am J. Pathol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249025
[Patent] SOX2由来のHLA-A24結合性癌抗原ペプチド2010
- Inventor(s)
  鳥越俊彦、廣橋良彦、中津川宗秀、佐藤昇志、高橋あかり
- Industrial Property Rights Holder
  北海道公立大学法人札幌医科大学、JST
- Filing Date
  2010-03-19
- Overseas
- Data Source
  KAKENHI-PROJECT-21590401
[Patent] サバイビン由来のHLA-A24結合性癌抗原ペプチド2010
- Inventor(s)
  佐藤昇志、鳥越俊彦、廣橋良彦、井手之上里美、小林淳一
- Industrial Property Rights Holder
  佐藤昇志、鳥越俊彦、廣橋良彦、井手之上里美、小林淳一
- Industrial Property Number
  2004-191478
- Filing Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21590401
[Patent] 抗原特異的T細胞誘導脳測定法2010
- Inventor(s)
  鳥越俊彦、廣橋良彦、水内将人、佐藤昇志、鈴木哲、清水佳隆、佐藤雄一郎
- Industrial Property Rights Holder
  鳥越俊彦、廣橋良彦、水内将人、佐藤昇志、鈴木哲、清水佳隆、佐藤雄一郎
- Filing Date
  2010-08-30
- Overseas
- Data Source
  KAKENHI-PROJECT-21590401
[Patent] 抗原特異的T細胞誘導脳測定法2010
- Inventor(s)
  鳥越俊彦、廣橋良彦、水内将人、佐藤昇志、鈴木哲、清水佳隆、佐藤雄一郎
- Industrial Property Rights Holder
  鳥越俊彦、廣橋良彦、水内将人、佐藤昇志、鈴木哲、清水佳隆、佐藤雄一郎
- Filing Date
  2010-08-30
- Overseas
- Data Source
  KAKENHI-PROJECT-21249025
[Patent] サバイビン由来のHLA-A 24結合性癌抗原ペプチド2010
- Inventor(s)
  佐藤昇志、鳥越俊彦、廣橋良彦、井手之上里美、小林淳一
- Industrial Property Rights Holder
  佐藤昇志、鳥越俊彦、廣橋良彦、井手之上里美、小林淳一
- Industrial Property Number
  2004-191478
- Filing Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21249025
[Patent] がん幹細胞分子マーカー2009
- Inventor(s)
  鳥越俊彦、廣橋良彦、佐藤昇志(他4名)
- Industrial Property Rights Holder
  鳥越俊彦、廣橋良彦、佐藤昇志(他4名)
- Filing Date
  2009-10-27
- Overseas
- Data Source
  KAKENHI-PROJECT-21249025
[Patent] がん幹細胞分子マーカー2009
- Inventor(s)
  鳥越俊彦, 廣橋良彦, 佐藤昇志, 上口権二郎, 守田玲菜, 西澤哲, 高橋あかり
- Industrial Property Rights Holder
  鳥越俊彦, 廣橋良彦, 佐藤昇志, 上口権二郎, 守田玲菜, 西澤哲, 高橋あかり
- Filing Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-21590401
[Patent] がん幹細胞分子マーカー2009
- Inventor(s)
  鳥越俊彦、廣橋良彦、佐藤昇志、上口権二郎、守田玲菜、西澤哲、高橋あかり
- Industrial Property Rights Holder
  北海道公立大学法人札幌医科大学、大日本住友製薬株式会社
- Filing Date
  2009-10-27
- Overseas
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] 組織レベルにおけるがん免疫応答解析2018
- Author(s)
  廣橋　良彦
- Organizer
  第59回日本組織細胞化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H01540
[Presentation] Immunoreaction to cancer stem cells2017
- Author(s)
  廣橋良彦
- Organizer
  第63回日本病理学会秋期特別総会
- Data Source
  KAKENHI-PROJECT-15H04722
[Presentation] Phosphorylation of HSF1 at Ser326 residue is associated with the maintenance of gynecologic cancer stem cells.2017
- Author(s)
  Toshihiko Torigoe, Yoshihiko Hirohashi, Kazuyo Yasuda, Aiko Murai, Tsuyoshi Saito, Noriyuki Sato
- Organizer
  The Eighth International Congress on Stress Proteins in Biology and Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01540
[Presentation] Immunothrapeutic strategy targeting cancer-stem cells2017
- Author(s)
  Yoshihiko Hirohashi
- Organizer
  The 36th Sapporo International Cancer Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01540
[Presentation] 癌精巣抗原BORISは婦人科癌幹細胞性に関与し、免疫療法のターゲットになりうる2017
- Author(s)
  廣橋良彦、浅野拓也、鳥越俊彦
- Organizer
  第56回日本臨床細胞学会秋期大会
- Data Source
  KAKENHI-PROJECT-15H04722
[Presentation] がん幹細胞に注目したがん免疫療法2017
- Author(s)
  廣橋良彦、塚原智英、金関貴幸、中津川宗秀、久保輝文、鳥越俊彦
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04722
[Presentation] Molecular Mechanism of Cancer Cell Hormesis2017
- Author(s)
  鳥越俊彦、廣橋良彦
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H01540
[Presentation] がん精巣抗原は、がん幹細胞標的免疫療法の有力な候補になる2016
- Author(s)
  廣橋　良彦
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台国際センター（仙台市）
- Data Source
  KAKENHI-PROJECT-15H04722
[Presentation] 癌精巣抗原BORISの肺癌幹細胞様細胞における発現とBORIS抗原を標的とした免疫療法の検討2016
- Author(s)
  堀部　亮多、廣橋　良彦
- Organizer
  第20回日本がん免疫学会総会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Data Source
  KAKENHI-PROJECT-15H04722
[Presentation] がん幹細胞標的免疫療法の開発2016
- Author(s)
  廣橋　良彦
- Organizer
  第14回日本臨床腫瘍学会学術集会
- Place of Presentation
  神戸国際展示場・神戸国際会議場（神戸市）
- Invited
- Data Source
  KAKENHI-PROJECT-15H04722
[Presentation] がん幹細胞を標的とした免疫療法2015
- Author(s)
  廣橋良彦
- Organizer
  第５回北海道探索病理学研究シンポジウム
- Place of Presentation
  ニューオータニイン札幌（札幌市）
- Year and Date
  2015-10-24
- Invited
- Data Source
  KAKENHI-PROJECT-15H04722
[Presentation] 免疫療法でがんは治せるのか？　~次世代のがん免疫療法~2015
- Author(s)
  廣橋良彦
- Organizer
  日本耳鼻咽喉科学会第９８回和歌山地方部会総会
- Place of Presentation
  和歌山県民文化会館（和歌山市）
- Year and Date
  2015-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-15H04722
[Presentation] Establishment of cancer stem cell-targeting immunotherapy2015
- Author(s)
  廣橋良彦
- Organizer
  第13回日本臨床腫瘍学会学術集会
- Place of Presentation
  ロイトン札幌（札幌市）
- Year and Date
  2015-07-16
- Invited
- Data Source
  KAKENHI-PROJECT-15H04722
[Presentation] The latest finding from SUCCESS : A phase I study of SVN-2B vaccination for metastatic gastrointestinal cancer patients2014
- Author(s)
  島　宏彰、水口　徹、里見　蕗乃、九冨　五郎、信岡　隆幸、木村　康利、古畑　智久、廣橋　良彦、鳥越　俊彦、佐藤　昇志、平田　公一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24659592
[Presentation] SVN-2Bペプチドがんワクチン療法：第Ⅰ相臨床試験”SUCCESS"から得た最新の知見2014
- Author(s)
  島　宏彰、水口　徹、里見　蕗乃、九冨　五郎、信岡　隆幸、木村　康利、古畑　智久、亀嶋　秀和、高橋あかり、塚原　智英、金関　貴幸、廣橋　良彦、鶴間　哲弘、岩山　祐司、田村　保明、鳥越　俊彦、佐藤　昇志、平田　公一
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール（松山市）
- Year and Date
  2014-07-31
- Data Source
  KAKENHI-PROJECT-24659592
[Presentation] がん幹細胞におけるストレス応答遺伝子の活性化とその意義2013
- Author(s)
  廣橋良彦
- Organizer
  第１０２回日本病理学会総会
- Place of Presentation
  札幌市
- Invited
- Data Source
  KAKENHI-PROJECT-24590449
[Presentation] がん幹細胞を標的とする免疫療法の基礎的検討2013
- Author(s)
  廣橋良彦、鳥越俊彦、守田玲菜、西澤　哲、井野田智子、髙橋あかり、佐藤昇志
- Organizer
  第１７回日本がん免疫学会総会
- Place of Presentation
  宇部市
- Invited
- Data Source
  KAKENHI-PROJECT-24590449
[Presentation] 新規HSP40ファミリーDNAJB8はがん幹細胞の維持に関わり、免疫療法の標的となりうる2013
- Author(s)
  廣橋良彦、鳥越俊彦、西澤　哲、原　勲、佐藤昇志
- Organizer
  日本ハイパーサーミア学会第３０回大会
- Place of Presentation
  横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-24590449
[Presentation] 腎臓癌の幹細胞と治療戦略2013
- Author(s)
  廣橋良彦
- Organizer
  第６回 Tokyo Metropolitan Kidney Cancer Meeting
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24590449
[Presentation] A novel cancer-initiating cell marker, OR7C1 can be a target of immunotherapy2013
- Author(s)
  Yoshihiko Hirohashi, Toshihiko Torigoe, Rena Morita, Satoshi Nishizawa, Satoko Inoda, Akari Takahashi and Noriyuki Sato
- Organizer
  第７２回日本がん学会総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24590449
[Presentation] 熱ショックによりがん抗原特異的細胞傷害活性T細胞機能が亢進する2013
- Author(s)
  廣橋良彦、鳥越俊彦、髙橋あかり、佐藤昇志
- Organizer
  第２９回日本ストレス学会総会
- Place of Presentation
  徳島市
- Invited
- Data Source
  KAKENHI-PROJECT-24590449
[Presentation] Cancer Immunotherapy targeting to cancer stem cell/cancer initiating cell2012
- Author(s)
  廣橋良彦
- Organizer
  第７１回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24659592
[Presentation] がん幹細胞標的ペプチドワクチン2012
- Author(s)
  廣橋良彦
- Organizer
  第１０回日本臨床腫瘍学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24659592
[Presentation] がん幹細胞の免疫学的特性とワクチン開発2011
- Author(s)
  鳥越俊彦、廣橋良彦、佐藤昇志
- Organizer
  第13回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Year and Date
  2011-02-11
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] がん幹細胞を標的とする免疫療法2011
- Author(s)
  廣橋良彦、佐藤昇志, 他
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21249025
[Presentation] 次世代がんワクチン:がん幹細胞標的ペプチドワクチンの実用化研究2011
- Author(s)
  鳥越俊彦、廣橋良彦、守田玲菜、田村保明、平田公一、佐藤昇志
- Organizer
  日本癌治療学会シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] がん幹細胞を標的とする免疫療法2011
- Author(s)
  廣橋良彦、鳥越俊彦、井野田智子、守田玲菜、高橋あかり、中津川宗秀、道振義貴、佐藤昇志
- Organizer
  第70回日本癌学会学術総会、シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] Stress Response Genes Expressed in Cancer Stem Cells-potent molecular targets for cancer therapy-2011
- Author(s)
  Toshihiko Torigoe, Hirohashi Yoshihiko, Yasuaki Tamura, Noriyuki Sato
- Organizer
  The 5^<th> International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Quebec City, Canada.
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] がん幹細胞の免疫病理学的特性の解析:がん幹細胞標的治療へ向けて2011
- Author(s)
  鳥越俊彦、廣橋良彦、佐藤昇志
- Organizer
  バイオセラピィ学会シンポジウム
- Place of Presentation
  和歌山
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] がん幹細胞の免疫学的特性とワクチン開発2011
- Author(s)
  鳥越俊彦、廣橋良彦、田村保明、佐藤昇志
- Organizer
  がん免疫学会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] Stress Response Genes Expressed in Cancer Stem Cells-potent molecular targets for cancer therapy2011
- Author(s)
  Toshihiko Torigoe, Hirohashi Yoshihiko, Yasuaki Tamura, Noriyuki Sato
- Organizer
  The 5^<th> International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  Quebec City, Canada
- Data Source
  KAKENHI-PROJECT-21249025
[Presentation] Immune responses against cancer stem cells2010
- Author(s)
  Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Sato
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] A novel DNAJ family protein is a cancer initiating cell antigen.-A potent molecular target for cancer immunotherapy-2010
- Author(s)
  Toshihiko Torigoe, Yoshihiko Hirohashi, Satoshi Nishizawa, Akari Takahashi, Hiroko Asanuma, Munehide Nakatsugawa, Kenjiro Kamiguchi, Alisa A. Sokolovskaya, Noriyuki Sato.
- Organizer
  The 8^<th> International Workshop on the Molecular Biology of Stress Responses
- Place of Presentation
  Seorak Mt., Korea
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] Immune responses against cancer stem cells2010
- Author(s)
  Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Sato
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21249025
[Presentation] Cancer initiating cellを標的とした免疫療法の基礎的研究2010
- Author(s)
  鳥越俊彦、廣橋良彦、佐藤昇志
- Organizer
  日本がん免疫学会、シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] A novel DNAJ family protein is a cancer initiating cell antigen.-A potent molecular target for cancer immunotherapy2010
- Author(s)
  Toshihiko Torigoe, Yoshihiko Hirohashi, Satoshi Nishizawa, Akari Takahashi, Hiroko Asanuma, Munehide Nakatsugawa, Kenjiro Kamiguchi, Alisa A. Sokolovskaya, Noriyuki Sato
- Organizer
  The 8th International Workshop on the Molecular Biology of Stress Responses
- Place of Presentation
  Seorak Mt., Korea
- Data Source
  KAKENHI-PROJECT-21249025
[Presentation] Identification of cancer stem cell antigens revealed unique characteristics of triple negative breast cancer2009
- Author(s)
  Torigoe, T., Hirohashi, Y., Takahashi, A., Asanuma, H., Nakatsugawa, M., Inoda, S., Sato, N.
- Organizer
  14th World Congress on Advances in Oncology and 12th International Symposium on Molecular Medicine
- Place of Presentation
  Loutraki, Greece
- Data Source
  KAKENHI-PROJECT-21249025
[Presentation] Identification of cancer stem cell antigens revealed unique characteristics of triple negative breast cancer2009
- Author(s)
  Torigoe, T., Hirohashi, Y., Takahashi, A., Asanuma, H., Nakatsugawa, M., Inoda, S., Sato, N.
- Organizer
  14th World Congress on Advances in Oncology and 12th International Symposium on Molecular Medicine
- Place of Presentation
  Loutraki, Greece
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] ヒト癌幹細胞に対する免疫応答2009
- Author(s)
  廣橋良彦、鳥越俊彦、佐藤昇志
- Organizer
  免疫アジュバント研究会
- Place of Presentation
  洞爺
- Data Source
  KAKENHI-PROJECT-21590401
[Presentation] Cancer Immunotherapy targeting to cancer stem cell/cancer initiating cell
- Author(s)
  廣橋良彦
- Organizer
  第７１回日本癌学会学術総会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-24590449
[Presentation] 6.Cytotoxic T lymphocytes play a key role in immunological responses to human cancer stem-like cells
- Author(s)
  廣橋良彦
- Organizer
  第33回　札幌がんセミナー国際シンポジウム
- Place of Presentation
  ロイトン札幌（北海道・札幌市）
- Year and Date
  2014-06-28 – 2014-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-24590449
[Presentation] ヒトがん幹細胞免疫制御の分子病理学的基盤
- Author(s)
  廣橋良彦
- Organizer
  第60回日本病理学会秋季特別総会
- Place of Presentation
  国立劇場おきなわ（沖縄県・浦添市）
- Year and Date
  2014-11-19 – 2014-11-20
- Invited
- Data Source
  KAKENHI-PROJECT-24590449
[Presentation] がん幹細胞標的ペプチドワクチン
- Author(s)
  廣橋良彦
- Organizer
  第１０回日本臨床腫瘍学会学術総会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-24590449

1. TORIGOE Toshihiko (20301400)

# of Collaborated Projects: 7 results

# of Collaborated Products: 92 results
2. KUTOMI Goro (10404625)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. SATO Noriyuki (50158937)

# of Collaborated Projects: 2 results

# of Collaborated Products: 55 results
4. TAMURA Yasuaki (80322329)

# of Collaborated Projects: 2 results

# of Collaborated Products: 35 results
5. 島宏彰 (00404616)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 和田朝香 (10830151)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 竹政伊知朗 (50379252)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. ICHIMIYA Shingo (30305221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. KIKUCHI Tomoki (50404588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. HIRATA Koichi (50136959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. MIZUGUCHI Toru (30347174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. KIMURA Yasutoshi (80311893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. OGAWA Tadashi (70516658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KOUNO Tsuyoshi (50516664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Kitamura Hiroshi (00404674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 舛森直哉 (20295356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. 前田俊浩 (40438015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 橋本真一 (00313099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. 塚原智英 (20404634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
20. 金関貴幸 (50531266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
21. 久保輝文 (90580019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
22. 中津川宗秀 (70448596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 里見蕗乃 (90563487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. KAMESHIMA Hidekazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. HIMI Tetsuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. ISHIDA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. KOBAYASHI Junichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. SASAKI Takanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. YAMAMOTO Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. TANAKA Toshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. TSUJIWAKI Mitsuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. HASEGAWA Tadashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. SUZUKI Hiromu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 高橋あかり

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
35. 守田玲菜

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
36. 佐々木泰史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. 時野隆至

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
38. 池原譲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 池原早苗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 畑泰司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 西田幸代

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 森満

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 宮崎晃亘

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
44. 平塚博義

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
45. 道振義貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
46. 藤野準己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 原勲

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
48. 西澤哲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 松崎純一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
50. 仲盛健治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 山口晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 丸山玲緒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 斉藤豪

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
54. 染谷正則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 土屋高旭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 長谷川智一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. VITALY Kochin

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
58. 小海康夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. 池尾一穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 松島綱治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. 伊藤利洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. 近藤亨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
63. 江森誠人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
64. 宮本昇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirohashi Yoshihiko 廣橋 良彦

HIROHASHI Yoshihiko 廣橋 良彦

Research Projects

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Co-Researchers

Single cell analysis of tumor-microenvironment based on TIL functionsPrincipal InvestigatorOngoing

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development of combined immunotherapy targeting ero1 in triple negative breast cancerOngoing

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乳癌の転移巣を伴うリンパ節内のT-cellにおける免疫応答Ongoing

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Basic research on the immunohistological categorization of tumor microenvironment

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Establishment of novel chemoimmunotherapy for urothelial cancer

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Immunological aspects of cancer stem cell and spermatogenesisPrincipal Investigator

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Immunological analysis of treatment resistant cancer stem cellsPrincipal Investigator

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Developing a novel vaccine therapy targeting cancer stem cells

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Molecular immunopathology of human cancer stem cell

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Basic studies for the immune responses against cancer stem cells of sold tumors

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[Book] がん免疫療法の標的抗原、がん免疫療法-実用化へのチャレンジ-2010

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[Book] Cancer, Immunology and Photonics S cience. Optical Devices and Systems, Biomedical and Green Technologies.2010

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[Book] Cancer, Immunology and Photonics Science. Optical Devices and Systems, Biomedical and Green Technologies2010

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[Book] バイオ医薬の開発技術とシーズ.第30章がんペプチド免疫治療2009

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[Journal Article] Differential bronchial epithelial response regulated by ΔNp63: a functional understanding of the epithelial shedding found in asthma.2019

Hirohashi Yoshihiko 廣橋良彦

HIROHASHI Yoshihiko 廣橋良彦