NAGATA TETSUYA 永田哲也

… Alternative Names

NAGATA Tetsuya 永田哲也

永田哲也ナガタテツヤ

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Researcher Number	50362976
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 東京医科歯科大学, 統合研究機構, 教授 2017 – 2022: 東京医科歯科大学, 大学院医歯学総合研究科, プロジェクト准教授 2018 – 2019: 東京医科歯科大学, 大学院医歯学総合研究科, 特任准教授 2016 – 2017: 東京医科歯科大学, 大学院医歯学総合研究科, プロジェクト講師 2015: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 客員研究員 … More 2015: 国立研究開発法人国立精神・神経医療研究センター, 遺伝子疾患治療研究部, 客員研究員 2015: 国立精神・神経医療研究センター神経研究所, 遺伝子疾患治療研究部, 客員研究員 2014: 独立行政法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 客員研究員 2014: 独立行政法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 客員研究員 2012 – 2013: 独立行政法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 室長 2012 – 2013: 独立行政法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 室長 2011: 独立行政法人国立精神・神経医療研究センター, 神経研究所・遺伝子疾患治療研究部, 室長 2010: 独立行政法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 室長 2005: 岡山大, 医学部・歯学部附属病院, 助手 2003 – 2004: 岡山大学, 医学部・歯学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Neurology / Medium-sized Section 47:Pharmaceutical sciences and related fields / Applied pharmacology Except Principal Investigator Basic Section 56010:Neurosurgery-related / Biomedical engineering/Biomaterial science and engineering / Neurology / Applied pharmacology
Keywords	Principal Investigator 核酸医薬 / ヘテロ核酸 / 臓器特異的 (脳・骨格筋) / 神経・筋疾患 / 臓器特異的 / 神経科学 / 脳神経疾患 / 核酸 / 中枢神経移行性 / アンチセンス核酸 … More / 神経難病 / 中枢移行 / 全身投与 / ノックアウトマウス / 蛍光偏光法 / 中枢神経 / 中枢移行性 / 神経変性疾患 / スキッピング / カヘキシア / エクソン・スキッピング / 筋疾患 / 脂質リガンド / 遺伝性筋疾患 / 骨格筋 / 心筋 / アンチセンス・オリゴヌクリオチド / デュシェンヌ型筋ジストロフィー / デュシェンヌ型筋ジストロフィー / アデノ随伴ベクター / アンチセンス・オリゴヌクレオチド / トランスレーショナルリサーチ / エクソン・スキップ / DMD / TRPV2 / TRPfamily / SAC / 神経分子病態学 / PSA-NCAM / 全般発作反復 / キンドリング / 移植 / 神経幹細胞 / てんかん … More Except Principal Investigator IGF-1 / SOD1 / 脳梗塞 / 細胞治療 / 血管新生 / 炎症抑制 / 脳虚血 / エクソソーム / 間葉系幹細胞 / バイオテクノロジー / 核酸 / Glut / Glut 1/4 / トランスフェリン / リサイクリング / 核酸医薬 / Glucose transporter / トランスフェリンレセプター / LDL受容体 / ヘテロ核酸 / 神経変性疾患 / 抗体工学 / トランスフェリン受容体 / グルコーストランスポーター / 血液脳関門 / hypoxia / neurotrophic factor / intrathecal administration / transgenic mice / Amyotrophic lateral sclerosis / ALS / モデル動物 / 神経栄養因子 / 髄腔内投与 / トランスジェニックマウス / 筋萎縮性側索硬化症 / エクソン・スキップ / アンチセンス / 重複変異 / ジストロフィン / 筋ジストロフィー / 遺伝子診断・治療 / 応用薬理学 Less

Development of innovative target organ-specific oligonucleotide therapyPrincipal Investigator
- Principal Investigator
  
  永田哲也
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Tokyo Medical and Dental University
羊膜間葉系幹細胞由来エクソソームを利用した次世代型脳梗塞治療法の確立
- Principal Investigator
  
  仁藤智香子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
Development of innovative nucleic acid therapy enabling any gene control in cardiac and skeletal musclePrincipal Investigator
- Principal Investigator
  
  Nagata Tetsuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Tokyo Medical and Dental University
Development of heteroduplex oligonucleotide crossing the blood-brain barrier
- Principal Investigator
  
  Yokota Takanori
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Medical and Dental University
Development of novel HDO that enables regulation of gene expression in CNS by systemic administrationPrincipal Investigator
- Principal Investigator
  
  NAGATA Tetsuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tokyo Medical and Dental University
Development of Antisense Mediated Therapy for Exons Duplication in Duchenne Muscular Dystrophy.
- Principal Investigator
  
  SAITO Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Center of Neurology and Psychiatry
Development of AAV-induced exonskipping therapy for Duchenne muscular dystrophyPrincipal Investigator
- Principal Investigator
  
  Nagata Tetsuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry
Study on Mechano-Sensing Channel in muscular dystrophic dogPrincipal Investigator
- Principal Investigator
  
  NAGATA Tetsuya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry
てんかんモデルにおける神経幹細胞移植と内在性神経幹細胞活性化を用いた治療Principal Investigator
- Principal Investigator
  
  永田哲也, 佐藤圭子
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Okayama University
The study for the molecular mechanisms and the newly developed treatment for ALS
- Principal Investigator
  
  ABE Koji
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Okayama University

[Book] 運動ニューロン疾患2017
- Author(s)
  永田哲也，吉岡耕太郎，横田隆徳
- Total Pages
  352
- Publisher
  中外医学社
- ISBN
  9784498228887
- Data Source
  KAKENHI-PROJECT-16H05221
[Book] 神経疾患治療ストラテジー2017
- Author(s)
  永田哲也，吉岡耕太郎，横田隆徳
- Total Pages
  451
- Publisher
  中山書店
- ISBN
  9784521745435
- Data Source
  KAKENHI-PROJECT-16H05221
[Book] 筋疾患診療ハンドブック：エクソン・スキップ2013
- Author(s)
  永田哲也, 武田伸一
- Total Pages
  5
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25461303
[Book] 筋疾患診療ハンドブック2013
- Author(s)
  永田哲也, 武田伸一（内野誠監）
- Total Pages
  206
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25460666
[Book] Challenges to oligonucleotides-based therapeutics, especially with regards to exon 51 skipping for Duchenne muscular dystrophy. Modeling, Simulation and Applied Optimization (ICMSAO)2011
- Author(s)
  Aoki Y, Shimizu Y, Nagata T, Takeda S
- Total Pages
  5775520
- Data Source
  KAKENHI-PROJECT-22590950
[Book] 筋ジストロフィーの新しい治療戦略.神経内科2011
- Author(s)
  永田哲也,武田伸一
- Data Source
  KAKENHI-PROJECT-22590950
[Book] The frontier of antisense oligonucleotide induced therapy. Fifty years of neuromuscular disorder research after discovery of creatine kinase as a diagnostic marker of muscular dystrophy(ed.by Takeda S)2011
- Author(s)
  Nagata T, et.al.
- Publisher
  TGAKU-SHOIN Ltd
- Data Source
  KAKENHI-PROJECT-22590950
[Book] The frontier of antisense oligonucleotide induced therapy (ed. by Takeda S). Fifty years of neuromuscular disorder research after discovery of creatine kinase as a diagnostic marker of muscular dystrophy2011
- Author(s)
  Nagata T, Takeda S
- Publisher
  IGAKU-SHOIN Ltd., Japan
- Data Source
  KAKENHI-PROJECT-22590950
[Journal Article] Regulation of activated microglia and macrophages by systemically administered DNA/RNA heteroduplex oligonucleotides2022
- Author(s)
  Nishi Rieko、Ohyagi Masaki、Nagata Tetsuya、Mabuchi Yo、Yokota Takanori
- Journal Title
  
  Molecular Therapy
  
  Volume: 30 Issue: 6 Pages: 2210-2223
- DOI
  10.1016/j.ymthe.2022.02.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10024, KAKENHI-PROJECT-18KK0449, KAKENHI-PROJECT-17H06109
[Journal Article] Short DNA/RNA heteroduplex oligonucleotide interacting proteins are key regulators of target gene silencing2021
- Author(s)
  Asada Ken、Sakaue Fumika、Nagata Tetsuya、Zhang Ji-chun、Yoshida-Tanaka Kie、Abe Aya、Nawa Makiko、Nishina Kazutaka、Yokota Takanori
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 9 Pages: 4864-4876
- DOI
  10.1093/nar/gkab258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01016
[Journal Article] DNA/RNA heteroduplex oligonucleotide technology for regulating lymphocytes in vivo2021
- Author(s)
  Ohyagi Masaki、Nagata Tetsuya、Ihara Kensuke、Yoshida-Tanaka Kie、Nishi Rieko、Miyata Haruka、Abe Aya、Mabuchi Yo、Akazawa Chihiro、Yokota Takanori
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 7344-7344
- DOI
  10.1038/s41467-021-26902-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02909, KAKENHI-PROJECT-21H03328, KAKENHI-PROJECT-18KK0449, KAKENHI-PROJECT-17H06109, KAKENHI-PROJECT-19H01016
[Journal Article] Effective silencing of miR-126 after ischemic stroke by means of intravenous α-tocopherol?conjugated heteroduplex oligonucleotide in mice2021
- Author(s)
  Suzuki Motohiro、Ishibashi Satoru、Iwasawa Eri、Oguma Takahiro、Saito Yasuhiro、Li Fuying、Otsu Shinichi、Ichinose Keiko、Yoshioka Kotaro、Nagata Tetsuya、Yokota Takanori
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 14237-14237
- DOI
  10.1038/s41598-021-93666-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07733, KAKENHI-PROJECT-20K09366, KAKENHI-PROJECT-19H01016
[Journal Article] Efficient Gene Suppression by DNA/DNA Double-Stranded Oligonucleotide In?Vivo2021
- Author(s)
  Asami Yutaro、Nagata Tetsuya、Yoshioka Kotaro、Kunieda Taiki、Yoshida-Tanaka Kie、Bennett C. Frank、Seth Punit P.、Yokota Takanori
- Journal Title
  
  Molecular Therapy
  
  Volume: 29 Issue: 2 Pages: 838-847
- DOI
  10.1016/j.ymthe.2020.10.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06109, KAKENHI-PROJECT-19H01016
[Journal Article] Structural tuning of oligonucleotides for enhanced blood circulation properties of unit polyion complexes prepared from two-branched poly(ethylene glycol)-block-poly(l-lysine)2021
- Author(s)
  Naito Mitsuru、Chaya Hiroyuki、Toh Kazuko、Kim Beob Soo、Hayashi Kotaro、Fukushima Shigeto、Nagata Tetsuya、Yokota Takanori、Kataoka Kazunori、Miyata Kanjiro
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 330 Pages: 812-820
- DOI
  10.1016/j.jconrel.2021.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18379, KAKENHI-PROJECT-19H01016
[Journal Article] Separation-related rapid nuclear transport of DNA/RNA heteroduplex oligonucleotide: unveiling distinctive intracellular trafficking2021
- Author(s)
  Ono Daisuke、Asada Ken、Yui Daishi、Sakaue Fumika、Yoshioka Kotaro、Nagata Tetsuya、Yokota Takanori
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 23 Pages: 1360-1370
- DOI
  10.1016/j.omtn.2020.11.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05550, KAKENHI-PROJECT-17H06109, KAKENHI-PROJECT-19H01016
[Journal Article] Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNS.2021
- Author(s)
  Nagata T, Dwyer CA, Yoshida-Tanaka K, Ihara K, Ohyagi M, Kaburagi H, Miyata H, Ebihara S, Yoshioka K, Ishii T, Miyata K, Miyata K, Powers B, Igari T, Yamamoto S, Arimura N, Hirabayashi H, Uchihara T, Hara RI, Wada T, Bennett CF, Seth PP, Rigo F, Yokota T
- Journal Title
  
  Nat Biotechnol
  
  Volume: 39 Issue: 12 Pages: 1529-1536
- DOI
  10.1038/s41587-021-00972-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03555, KAKENHI-PROJECT-21H02909, KAKENHI-PROJECT-23K21353, KAKENHI-PROJECT-17H06109, KAKENHI-PROJECT-19H01016
[Journal Article] Efficacy of Multi-exon Skipping Treatment in Duchenne Muscular Dystrophy Dog Model Neonates.2019
- Author(s)
  Lim KRQ*, Echigoya Y* (* equally contributed), Nagata T, Kuraoka M, Kobayashi M, Aoki Y, Partridge T, Maruyama R, Takeda S, Yokota T.
- Journal Title
  
  Molecular Therapy
  
  Volume: 27(1) Issue: 1 Pages: 76-86
- DOI
  10.1016/j.ymthe.2018.10.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14595, KAKENHI-PROJECT-16H05221
[Journal Article] Synthesis of 2'-O-(N-methylcarbamoylethyl) 5-methyl-2-thiouridine and its application to splice-switching oligonucleotides.2019
- Author(s)
  Masaki Y, Yamamoto K, Inde T, Yoshida K, Maruyama A, Nagata T, Tanihata J, Takeda S, Sekine M, Seio K
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 29 Issue: 2 Pages: 60-163
- DOI
  10.1016/j.bmcl.2018.12.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08726, KAKENHI-PROJECT-17H04886, KAKENHI-PROJECT-16H05221
[Journal Article] NS-065/NCNP-01: An Antisense Oligonucleotide for Potential Treatment of Exon 53 Skipping in Duchenne Muscular Dystrophy2018
- Author(s)
  Watanabe Naoki、Nagata Tetsuya、Satou Youhei、Masuda Satoru、Saito Takashi、Kitagawa Hidetoshi、Komaki Hirofumi、Takagaki Kazuchika、Takeda Shin’ichi
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 13 Pages: 442-449
- DOI
  10.1016/j.omtn.2018.09.017
- Data Source
  KAKENHI-PROJECT-16H05221
[Journal Article] Truncated dystrophin ameliorates the dystrophic phenotype of mdx mice by reducing sarcolipin-mediated SERCA inhibition2018
- Author(s)
  Tanihata Jun、Nagata Tetsuya、Ito Naoki、Saito Takashi、Nakamura Akinori、Minamisawa Susumu、Aoki Yoshitsugu、Ruegg Urs T.、Takeda Shin'ichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 505 Issue: 1 Pages: 51-59
- DOI
  10.1016/j.bbrc.2018.09.039
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01529, KAKENHI-PROJECT-16K08726, KAKENHI-PROJECT-16K15184, KAKENHI-PROJECT-16H05221
[Journal Article] Synthesis and thermal stabilities of oligonucleotides containing 2'-O,4'-C-methylene bridged nucleic acid with a phenoxazine base2017
- Author(s)
  Yuki Kishimoto, Akane Fujii, Osamu Nakagawa, Tetsuya Nagata, Takanori Yokota, Yoshiyuki Hari, Satoshi Obika
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 15 Issue: 38 Pages: 8145-8152
- DOI
  10.1039/c7ob01874f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08024, KAKENHI-PROJECT-16H05221
[Journal Article] Enhancement of exon skipping in mdx52 mice by 2´-O-methyl- 2-thioribothymidine incorporation into phosphorothioate oligonucleotides2015
- Author(s)
  Masaki Y, Inde T, Nagata T, Tanihata J, Kanamori T, Seio K, Takeda S, Sekine M.
- Journal Title
  
  Med. Chem. Commun.,
  
  Volume: 6 Issue: 4 Pages: 630-633
- DOI
  10.1039/c4md00468j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461303
[Journal Article] Long-term efficacy of systemic multiexon skipping targeting dystrophin exons 45-55 with a cocktail of vivo-morpholinos in mdx52 mice.2015
- Author(s)
  Echigoya Y, Aoki Y, Miskew B, Panesar D, Touznik A, Nagata T, Tanihata J, Nakamura A, Nagaraju K, Yokota T
- Journal Title
  
  Mol Ther Nucleic Acids
  
  Volume: 4 Pages: e225-e225
- DOI
  10.1038/mtna.2014.76
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860306, KAKENHI-PROJECT-25460666, KAKENHI-PROJECT-25461303
[Journal Article] Prognostic impact of venous thromboembolism in patients with Duchenne muscular dystrophy: Prospective multicenter 5-year cohort study.2015
- Author(s)
  Kimura K, Morita H, Daimon M, Kawata T, Nakao T, Lee SL, Hirokawa M, Ebihara A, Nakajima T, Ozawa T, Yonemochi Y, Aida I, Motoyoshi Y, Mikata T, Uchida I, Komori T, Kitao R, Nagata T, Takeda S, Komaki H, Segawa K, Takenaka K, Komuro I.
- Journal Title
  
  Int J Cardiol.
  
  Volume: 191 Pages: 178-80
- DOI
  10.1016/j.ijcard.2015.04.244
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461303
[Journal Article] Necroptosis drives motor neuron death in models of both sporadic and familial ALS.2014
- Author(s)
  Re DB, Le Verche V, Yu C, Amoroso MW, Politi KA, Phani S, Ikiz B, Hoffmann L, Koolen M, Nagata T, Papadimitriou D, NagyP, Mitsumoto H, Kariya S, Wichterle H, Henderson CE, Przedborski S.
- Journal Title
  
  Neuron
  
  Volume: 81(5) Issue: 5 Pages: 1001-1008
- DOI
  10.1016/j.neuron.2014.01.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461303
[Journal Article] Mutation types and aging differently affect revertant fiber expansion in dystrophic mdx and mdx52 mice.2013
- Author(s)
  Echigoya Y, Lee J, Rodrigues M, Nagata T, Tanihata J, Nozohourmehrabad A, Panesar D, Miskew B, Aoki Y, Yokota T.
- Journal Title
  
  PLoS One
  
  Volume: 8(7) Issue: 7 Pages: e69194-e69194
- DOI
  10.1371/journal.pone.0069194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461303, KAKENHI-PROJECT-25860306
[Journal Article] Highly efficient in vivo delivery of PMO into regenerating myotubes and rescue in laminin-α2 chain-null congenital muscular dystrophy mice2013
- Author(s)
  Aoki Y, Nagata T, Yokota T, Nakamura A, Wood MJ, Partridge T, Takeda S
- Journal Title
  
  Hum Mol Genet
  
  Volume: 22 Issue: 24 Pages: 4914-4928
- DOI
  10.1093/hmg/ddt341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500472, KAKENHI-PROJECT-25460666, KAKENHI-PROJECT-25461303
[Journal Article] Prognostic impact of left ventricular noncompaction in patients with Duchenne/Becker muscular dystrophy - Prospective multicenter cohort study2013
- Author(s)
  Kimura K, Komuro I (21人中21番目)
- Journal Title
  
  Int J Cardiol
  
  Volume: 168 Issue: 3 Pages: 1900-1904
- DOI
  10.1016/j.ijcard.2012.12.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229010, KAKENHI-PROJECT-25461303
[Journal Article] Extensive and prolonged restoration of dystrophin expression with vivo-morpholino-mediated multiple exon skipping in dystrophic dogs.2012
- Author(s)
  Yokota T, Nakamura A, Saito T, Nagata T, Partridge T, Hoffman E, Takeda S.
- Journal Title
  
  Nucleic Acid Ther
  
  Volume: 22 Issue: 5 Pages: 306-315
- DOI
  10.1089/nat.2012.0368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300157, KAKENHI-PROJECT-22590950, KAKENHI-PROJECT-24500472
[Journal Article] Demonstration of systemic exon 45-55 multiple skipping in dystrophic mdx52 mice2012
- Author(s)
  Aoki Y, Yokota T, Nagata T, Nakamura A, Nagaraju K, Hoffman E, Partridge T, Takeda S.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 109 Issue: 34 Pages: 13763-13768
- DOI
  10.1073/pnas.1204638109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300157, KAKENHI-PROJECT-22590950, KAKENHI-PROJECT-24500472
[Journal Article] Synthesis of 2'-O- [2-(N-Methylcarbamoyl)ethyl] ribonucleosides using oxa-michael reaction and chemical and biological properties of oligonucleotide derivatives incorporating these modified ribonucleosides.2011
- Author(s)
  Yamada T, Okaniwa N, Saneyoshi H, Ohkubo A, Seio K, Nagata T, Aoki Y, Takeda S, Sekine M.
- Journal Title
  
  J Org Chem.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590950
[Journal Article] Synthesis of 2'-O-[2-(N-Methylcarbamoyl)ethyl]ribonucl eosides Using Oxa-Michael reaction and chemical and biological properties of oligonucleotide derivatives incorporating these modified ribonucleosides.2011
- Author(s)
  Yamada T, Okaniwa N, Saneyoshi H, Ohkubo A, Seio K, Nagata T, Aoki Y, Takeda S, Sekine M
- Journal Title
  
  J Org Chem
  
  Volume: 76 Issue: 9 Pages: 3042-3053
- DOI
  10.1021/jo101963z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590950
[Journal Article] In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse.2010
- Author(s)
  Aoki Y, Nakamura A, Yokota T, Saito T, Okazawa H, Nagata T, Takeda S.
- Journal Title
  
  Mol Ther.
  
  Volume: 18 Pages: 1995-2005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590950
[Journal Article] In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse2010
- Author(s)
  Aoki Y, Nakamura A, Yokota T, Saito T, Okazawa H, Nagata T, Takeda S
- Journal Title
  
  Mol Ther
  
  Volume: 18 Pages: 1995-2005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590950
[Journal Article] Prevention of spinal motor neuron death by insulin-like growth factor-1 associating with the signal transduction systems in SOD (G93A) transgenic mice.2005
- Author(s)
  Narai H, Nagano I, Ilieva H, Shiote M, Nagata T, Hayashi T, Shoji M, Abe K.
- Journal Title
  
  Journal of the Neuroscience Research 82
  
  Pages: 452-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390273
[Journal Article] Prevention of spinal motor neuron death by IGF-1 associating with the signal transduction systems in SOD Tg mice.2005
- Author(s)
  Narai H, Nagano I, Ilieva H, Shiote M, Nagata T, Hayashi T, Shoji M, Abe K.
- Journal Title
  
  J.Neurosci.Res. 82
  
  Pages: 452-457
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390273
[Journal Article] Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed to hypoxia.2005
- Author(s)
  Shiote M, Nagano I, Ilieva H, Murakami T, Narai H, Ohta Y, Nagata T, Shoji M, Abe K.
- Journal Title
  
  Neuroscience 132(1)
  
  Pages: 175-182
- Data Source
  KAKENHI-PROJECT-15390273
[Journal Article] Reduction of a VEGF receptor, Flk-1, by antisense oligonucleotides induces motor Neuron death in rat spinal cord exposed to hypoxia2005
- Author(s)
  Shiote M, Nagano I, Ilieva H, Murakami T, Narai H, Ohta Y, Nagata T, Shoji M, Abe K.
- Journal Title
  
  Neuroscience 132
  
  Pages: 175-182
- Data Source
  KAKENHI-PROJECT-15390273
[Journal Article] Prevention of spinal motor neuron death by insulin-like growth factor-1 associating with the signal transduction systems in SOD(G93A) transgenic mice.2005
- Author(s)
  Narai H, Nagano I, Ilieva H, Shiote M, Nagata T, Hayashi T, Shoji M, Abe K.
- Journal Title
  
  Journal of the Neuroscience Research 82
  
  Pages: 452-457
- Data Source
  KAKENHI-PROJECT-15390273
[Journal Article] Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed to hypoxia.2005
- Author(s)
  Shiote M, Nagano I, Ilieva H, Murakami T, Narai H, Ohta Y, Nagata T, Shoji M, Abe K.
- Journal Title
  
  Neuroscience 132
  
  Pages: 175-182
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390273
[Journal Article] Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed to hypoxla.2005
- Author(s)
  Shiote M, Nagano I, Ilieva H, Murakami T, Narai H, Ohta Y, Nagata T, Shoji M, Abe K.
- Journal Title
  
  Neuroscience 132(1)
  
  Pages: 175-82
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390273
[Journal Article] Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene.2003
- Author(s)
  Murakami T, Ilieva H, Shiote M, Nagata T, Nagano I, Shoji M, Abe K.
- Journal Title
  
  Brain Res. 989
  
  Pages: 231-237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390273
[Patent] 脳血液関門通過型ヘテロ２本鎖核酸2019
- Inventor(s)
  横田隆徳。永田哲也
- Industrial Property Rights Holder
  東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-16H05221
[Patent] 脳血液関門通過型ヘテロ２本鎖核酸2019
- Inventor(s)
  横田隆徳。永田哲也
- Industrial Property Rights Holder
  東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-16H05221
[Patent] 脳血液関門通過型ヘテロ２本鎖核酸2019
- Inventor(s)
  横田隆徳。永田哲也
- Industrial Property Rights Holder
  東京医科歯科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-540337
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H05221
[Patent] アンチセンス核酸2013
- Inventor(s)
  武田伸一，永田哲也，他
- Industrial Property Rights Holder
  武田伸一，永田哲也，他
- Industrial Property Rights Type
  特許
- Filing Date
  2013-09-05
- Acquisition Date
  2014-03-27
- Data Source
  KAKENHI-PROJECT-25461303
[Patent] アンチセンス核酸2012
- Inventor(s)
  武田伸一，永田哲也，他
- Industrial Property Rights Holder
  国立精神・神経医療研究センター
- Industrial Property Rights Type
  特許
- Filing Date
  2012-12-27
- Data Source
  KAKENHI-PROJECT-22590950
[Patent] アンチセンス核酸2010
- Inventor(s)
  武田伸一,永田哲也ら
- Industrial Property Rights Holder
  武田伸一,永田哲也ら
- Filing Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] デュシャンヌ型筋ジストロフィーに対する核酸医薬2020
- Author(s)
  永田哲也
- Organizer
  第38回日本神経治療学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01016
[Presentation] ヘテロ核酸による遺伝子発現抑制2018
- Author(s)
  永田　哲也、横田　隆徳
- Organizer
  第34回日本DDS学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05221
[Presentation] Development of oligonucleotide therapies for neurodegenerative disease2018
- Author(s)
  Tetsuya Nagata
- Organizer
  第41回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05221
[Presentation] 核酸医薬品開発の現状2018
- Author(s)
  永田　哲也
- Organizer
  BioJapan
- Invited
- Data Source
  KAKENHI-PROJECT-16H05221
[Presentation] Recent progress of DNA/RNA heteroduplex oligonucleotide2018
- Author(s)
  Tetsuya Nagata
- Organizer
  59回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05221
[Presentation] The effect of DNA/RNA heteroduplex oligonucleotides on muscle2017
- Author(s)
  Nagata T, Ohyagi M, Ihara K , Kaburagi H, Nishina K, Piao W, Yoshida-Tanaka K, Huijia G, Kuwahara H, Yoshioka K, Yokota T
- Organizer
  23th World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05221
[Presentation] 核酸医薬による認知症・神経変性疾患の治療法開発2017
- Author(s)
  永田哲也
- Organizer
  第36回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05221
[Presentation] Development of antisense oligonucleotide with a new type of a double stranded structure2016
- Author(s)
  KUNIEDA T, YOSHIOKA K, SUJINO Y, TANAKA K, PIAO W, KUWAHARA H, NISHINA K, NAGATA T, YOKOTA T
- Organizer
  The 21st annual meeting of the RNA society
- Place of Presentation
  Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05221
[Presentation] Duchenne 型筋ジストロフィーに対するエクソン53スキップ治療薬の早期探索的臨床試験2015
- Author(s)
  永田哲也, 齊藤崇, 増田智, 鈴木麻衣子, 中村治雅, 小牧宏文, 武田伸一.
- Organizer
  第33回日本神経治療学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25461303
[Presentation] First-in-Human Study of NS-065/NCNP-01; the Morpholino Based Antisense Oligonucleotide for Exon 53 Skipping in Duchenne Muscular Dystrophy.2015
- Author(s)
  Saito T, Nagata T, Masuda S, Aoki Y, Suzuki M, Nakamura H, Komaki H, Takeda S
- Organizer
  American society of gene & cell therapy 18th Annual meeting
- Place of Presentation
  Hyatt Regency
- Year and Date
  2015-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461303
[Presentation] First-in-Human Study of NS-065/NCNP-01; the Morpholino Based Antisense Oligonucleotide for Exon 53 Skipping in Duchenne Muscular Dystrophy2015
- Author(s)
  Saito T, Nagata T, Masuda S, Aoki Y, Suzuki M, Nakamura H, Komaki H, Takeda S
- Organizer
  American society of gene & cell therapy 18th Annual meeting
- Place of Presentation
  Hyatt Regency, New Orleans, USA
- Year and Date
  2015-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460666
[Presentation] デュシェンヌ型筋ジストロフィーに対するエクソン53スキップ治療薬の早期探索的臨床試験2015
- Author(s)
  永田哲也, 齊藤崇, 増田智, 鈴木麻衣子, 中村治雅, 小牧宏文, 武田伸一.
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-25461303
[Presentation] Exon45-55 を欠失した短縮型dystrophin の機能的役割の解明2013
- Author(s)
  谷端淳，永田哲也，齊藤崇，青木吉嗣，清水裕子，中村昭則，武田伸一
- Organizer
  第68 回日本体力医学会
- Place of Presentation
  日本教育会館東京
- Data Source
  KAKENHI-PROJECT-25461303
[Presentation] Duchenne 型筋ジストロフィーに対するエクソン53 スキップによる早期探索的臨床試験2013
- Author(s)
  永田哲也，齊藤　崇，清水玲子，小牧宏文，武田伸一
- Organizer
  第31回日本神経治療学会総会
- Place of Presentation
  東京ドームホテル，千代田区
- Data Source
  KAKENHI-PROJECT-25460666
[Presentation] Duchenne 型筋ジストロフィーに対するエクソン53 スキップによる早期探索的臨床試験2013
- Author(s)
  永田哲也，齊藤崇，清水玲子，小牧宏文，武田伸一
- Organizer
  第31 回日本神経治療学会総会
- Place of Presentation
  東京ドームホテル　東京
- Data Source
  KAKENHI-PROJECT-25461303
[Presentation] Myogenic Transduction and Cell Surface Marker Selection of DMD Fibroblasts for Exon Skipping Assay.2012
- Author(s)
  Saito T, Nagata T, Aoki Y, Tanihata J, Masuda S, Yokota T, Motohashi Y, Takeda S
- Organizer
  The 11th Annual Scientific meeting of The Asian Oceanian Myology Center
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Myogenic Transduction and Cell Surface Marker Selection of DMD Fibroblasts Stable Dystrophin mRNA Expression for Exon Skipping Assay2012
- Author(s)
  Saito T, Nagata T, Aoki Y, Tanihata J, Masuda S, Yokota T, Shimizu-Motohashi Y, Takeda S
- Organizer
  American society of gene & cell therapy 15th Annual meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2012-05-17
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Exon skipping approach;exon 45-55 skipping2012
- Author(s)
  Tetsuya Nagata
- Organizer
  9th Japanese-French Symposium for `muscular dystrophy', Tokyo
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Exon skipping approach; exon 45-55 skipping.2012
- Author(s)
  Nagata T
- Organizer
  9th Japanese-French Symposium for ‘muscular dystrophy’
- Place of Presentation
  Tokyo,Japan（JA Kyosai building, Conference hall）
- Invited
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] mdx及びmdx52マウスを用いたin vivoおよびin vitroでのエクソン・スキップ効率の検討2012
- Author(s)
  永田哲也
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京(東京国際フォーラム）
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Demonstration of Systemic Exon 45-55 Multiple Skipping in Dystrophic mdx52 Mice2012
- Author(s)
  Aoki Y, Nagata T, Nakamura A, Saito T, Tanihata J, Duguez S , Nagaraju K, Hoffman E, Partridge T, Yokota T, Takeda S
- Organizer
  American society of gene & cell therapy 15th Annual meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2012-05-16
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Mechanism of uptaking Morpholino into dystrophin-deficient muscle fibers2011
- Author(s)
  Aoki Y, Nagata T, Yokota T, Takeda S
- Organizer
  American society of gene & cell therapy 14th Annual meeting
- Place of Presentation
  Seattle, USA
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Challenges for antisense oligonucleotide based therapeutics, in particular for exon 51-skipping in Duchenne muscular dystrophy2011
- Author(s)
  Aoki Y, Nagata T, Shimizu Y, Takeda S
- Organizer
  4th International conference on modeling, simulation and applied optimization
- Place of Presentation
  Kuala Lumpur, Malaysia
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Feasibility and Effectiveness of Exon 51-Skipping in Human-Like mdx Mutation.2010
- Author(s)
  Aoki Y, Saito T, Yokota T, Nakamura A, Okazawa H, Nagata T, Takeda S.
- Organizer
  American Society of Gene and Cell Therapy 2010
- Place of Presentation
  Washington DC Marriott Wardman Park Hotel
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Skipping of exons 6 and 8 of the DMD gene has been achieved in myogenic cells from an exon-7 deleted DMD patient : direct application of antisense sequences found in study with canine muscular dystrophy2010
- Author(s)
  Shimizu Y, Aoki Y, Saito T, Yokota T, Nagata T, Nakamura A, Osawa M, Takeda S
- Organizer
  The 15th World Muscle Society Congress-2010
- Place of Presentation
  Kumamoto Sojo University Municipal Auditorium (Kumamoto Citizens' Hall)
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Feasibility and effectiveness of exon 51 skipping in human-like mdx mutation2010
- Author(s)
  Aoki Y, Yokota T, Saito T, Nakamura A, Nagata T, Okazawa H, Takeda S
- Organizer
  American Society of Gene & Cell Therapy 13th Annual meeting
- Place of Presentation
  Washington DC, USA
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] シンポジウムAntisense Oligos for Muscular Dystrophyアンチセンスオリゴを用いた筋ジストロフィーの治療2010
- Author(s)
  永田哲也
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Antisence oligos for muscular dystrophy2010
- Author(s)
  永田哲也
- Organizer
  第51回日本神経学会総会シンポジウム「アカデミア発の創薬・治療研究」
- Place of Presentation
  東京・東京国際フォーラム
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Skipping of exons 6 and 8 of the DMD gene has been achieved in myogenic cells from an exon-7 deleted DMD patient: direct application of antisense sequences found in study with canine muscular dystrophy2010
- Author(s)
  Shimizu Y, Saito T, Aoki Y, Yokota T, Nagata T, Nakamura A, Osawa M, Takeda S
- Organizer
  15th International Congress of World Muscle Society (WMS)
- Place of Presentation
  Kumamoto
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-22590950
[Presentation] Duchenne 型筋ジストロフィーに対するエクソン53スキップ治療薬の早期探索的臨床試験
- Author(s)
  永田哲也，齊藤　崇，清水玲子，谷端淳，青木吉嗣，小牧宏文，武田伸一
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461303
[Presentation] Assessment of the Dystrophin Gene Exon 53 Skipping Using DMD Patient-Derived Fibroblasts for Exploratory Clinical Trial of Antisense Drug NS-065/NCNP-01.
- Author(s)
  Saito T, Nagata T, Masuda S, Tanihata J, Ohata M, Tamaura A, Kanazawa M, Minami N, Goto K, Hayashi Y, Iwasawa K, Tatezawa K, Fukuda K, Mizutani T, Shimizu R, Suzuki M, Yamaguchi K, Tachimori H, Nishino I, Goto Y, Komaki H, Takeda S.
- Organizer
  American society of gene & cell therapy 17th Annual meeting
- Place of Presentation
  Marriott Wardman Park Hotel
- Year and Date
  2014-05-20 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461303
[Presentation] Exon45-55を欠失した短縮型dystrophinはRyR1をニトロシル化し、細胞内Ca2＋濃度を上昇させる
- Author(s)
  谷端　淳，永田哲也，齊藤　崇，伊藤尚基，中村昭則，武田伸一
- Organizer
  第69回日本体力医学会大会
- Place of Presentation
  長崎大学文教キャンパス
- Year and Date
  2014-09-19 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-25461303
[Presentation] Assessment of the Dystrophin Gene Exon 53 Skipping Using DMD Patient-Derived Fibroblasts for Exploratory Clinical Trial of Antisense Drug NS-065/NCNP-01
- Author(s)
  Saito T, Nagata T, Masuda S, Tanihata J, Ohata M, Tamaura A, Kanazawa M, Minami N, Goto K, Hayashi Y, Iwasawa K, Tatezawa K, Fukuda K, Mizutani T, Shimizu R, Suzuki M, Yamaguchi K, Tachimori H, Nishino I, Goto Y, Komaki H, Takeda S
- Organizer
  American society of gene & cell therapy 17th Annual meeting
- Place of Presentation
  Marriott Wardman Park, Washington, DC, USA
- Year and Date
  2014-05-20 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-25460666
[Presentation] Truncated dystrophin with exon 45-55 deletion induced muscle atrophy and fiber type change through the hyper- nitrosylation of the ryanodine receptor type-1 and constant release of Ca2+ to the cytosol.
- Author(s)
  Tanihata J, Nagata T, Saito T, Ito N, Aoki Y, Nakamura A, Takeda S.
- Organizer
  19th International Congress of the World Muscle Societ
- Place of Presentation
  Humboldt Graduate School
- Year and Date
  2014-10-07 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-25461303

1. ABE Koji (20212540)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. TAKEDA Shin'ichi (90171644)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
3. SAITO Takashi (40625969)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. Yokota Takanori (90231688)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 原倫太朗 (70709766)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 宮田完二郎 (50436523)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 仁藤智香子 (30409172)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. IWATA Yuko (80171908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Okada Takashi (00326828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SHOJI Mikio (60171021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. NAGAI Makiko (80420488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HAYASHI Takeshi (40314679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 佐藤圭子 (20325103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 永野功 (80335603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
15. 津本浩平 (90271866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 須田智 (00366733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 宮川世志幸 (90415604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 笠原優子 (90391911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. AOKI Yoshitsugu

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. TANIHATA Jun

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
21. NAKAMURA Akinori

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. MASUDA Satoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. MOTOHASHI Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. YOKOTA Toshifumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. ISHIBASHI Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. NAKAGAWA Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. YOSHIDA Mari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 馬渕洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 越後谷裕介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 井原健介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 小室一成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 南沢享

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 内藤瑞

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 浅田健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 内原俊記

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGATA TETSUYA 永田 哲也

NAGATA Tetsuya 永田 哲也

永田 哲也 ナガタ テツヤ

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Development of innovative target organ-specific oligonucleotide therapyPrincipal Investigator

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羊膜間葉系幹細胞由来エクソソームを利用した次世代型脳梗塞治療法の確立

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Development of innovative nucleic acid therapy enabling any gene control in cardiac and skeletal musclePrincipal Investigator

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Development of heteroduplex oligonucleotide crossing the blood-brain barrier

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Development of novel HDO that enables regulation of gene expression in CNS by systemic administrationPrincipal Investigator

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Development of Antisense Mediated Therapy for Exons Duplication in Duchenne Muscular Dystrophy.

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Development of AAV-induced exonskipping therapy for Duchenne muscular dystrophyPrincipal Investigator

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Study on Mechano-Sensing Channel in muscular dystrophic dogPrincipal Investigator

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てんかんモデルにおける神経幹細胞移植と内在性神経幹細胞活性化を用いた治療Principal Investigator

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The study for the molecular mechanisms and the newly developed treatment for ALS

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[Book] 運動ニューロン疾患2017

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[Book] 神経疾患治療ストラテジー2017

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[Book] 筋疾患診療ハンドブック：エクソン・スキップ2013

Author(s)

NAGATA TETSUYA 永田哲也

NAGATA Tetsuya 永田哲也

永田哲也ナガタテツヤ