Miyata Kanjiro 宮田完二郎

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MIYATA Kanjiro 宮田完二郎

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Researcher Number	50436523
Other IDs	https://orcid.org/0000-0001-7044-190X
Affiliation (Current)	2025: 東京大学, 大学院工学系研究科(工学部), 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京大学, 大学院工学系研究科(工学部), 教授 2016 – 2021: 東京大学, 大学院工学系研究科(工学部), 准教授 2017: 東京大学, 大学院工学系研究科, 准教授 2016: 東京大学, 疾患生命工学センター, 准教授 2015 – 2016: 東京大学, 工学(系)研究科(研究院), 准教授 … More 2014: 東京大学, 大学院医学系研究所, 准教授 2012 – 2014: 東京大学, 医学(系)研究科(研究院), 准教授 2012: 東京大学, 医学(系)研究科(研究院), 助教 2009 – 2012: 東京大学, 大学院・医学系研究科, 助教 2010: 東京大学, 大学院・医系研究科, 助教 2008: 東京大学, 大学院・工学系研究科, 助教 2007 – 2008: The University of Tokyo, 大学院・工学系研究科, 特任助教 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering/Biomaterial science and engineering / Biomedical engineering/Biomaterial science and engineering / Basic Section 90120:Biomaterials-related / Biomedical engineering/Biological material science / Polymer chemistry Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Urology / Biomedical engineering/Biomaterial science and engineering / Basic Section 47060:Clinical pharmacy-related … More / Chemistry / Science and Engineering / Polymer chemistry / Biomedical engineering/Biological material science / Biological Sciences Less
Keywords	Principal Investigator 薬物送達システム / 核酸医薬デリバリー / 核酸医薬 / ポリイオンコンプレックス / siRNA / ドラッグデリバリー / ポリペプチド / ナノ医薬 / 核酸医薬送達 / ブロック共重合体 … More / 生体適合性 / 生分解性 / 免疫原性 / 自発分解性高分子 / 生体内共焦点顕微鏡 / 光応答性 / 高分子ナノ医薬 / photosensitizer / scintillator / drug delivery / X ray / photodynamic therapy / X線 / 光線力学療法 / Amphiphile / Transfection / Messenger RNA / Cationic polymer / 両親媒性ポリペプチド / メッセンジャーRNAデリバリー / CRISPR / amphiphilic polymer / Muscular dystrophy / polymeric micelle / polyplex / messenger RNA delivery / Cas9 / ペプチドリガンド / P-Body / エクソソーム / RNA / 中空粒子 / 核酸ベシクル / ポリイオンコンプレックス膜 / オリゴ核酸 / 人工エクソソーム / アンチジーン核酸 / 生体適合性高分子 / 機能性核酸 / 脳疾患 / 核酸デリバリー / 高分子材料 / がん治療 / 生体材料 / 機能性高分子 / バイオコンジュゲート材料 / siRNA デリバリー / 架橋 / 高分子ミセル / 遺伝子治療 … More Except Principal Investigator siRNA / ドラッグデリバリー / 高分子ミセル / ヘテロ核酸 / 血液脳関門 / 核酸医薬 / グルコーストランスポーター / ナノミセル / 膀胱癌 / マイクロRNA / ブロック共重合体 / がん治療 / 遺伝子治療 / バイオテクノロジー / 核酸 / Glut / Glut 1/4 / トランスフェリン / リサイクリング / Glucose transporter / トランスフェリンレセプター / LDL受容体 / 神経変性疾患 / 抗体工学 / トランスフェリン受容体 / グルコースミセル / ウイルス感染 / 脳 / 二重標的ミセル / 脳幹 / 嗅球 / RNA送達 / ウイルス脳感染 / RNAデリバリー / ナノ粒子 / Nose-to-Brain / 合成高分子 / 単鎖抗体 / 多剤耐性菌 / 吸入 / mRNA医薬 / グルコーストランスポ-ター / 脳―血液関門 / 脳一血液関門 / アルツハイマー病 / 脳-血液関門 / 抗体医薬 / プラスミドDNA / メッセンジャーRNA / アンチセンス核酸 / 血液脳関門（BBB） / 薬物送達システム / ポリアミノ酸 / ポリエチレングリコール / microRNA / 癌抑制型マイクロRNA / ポリ(L-リジン) (PLL) / 腎疾患 / がん / ポリ(L-リジン)(PLL) / ポリエチレングリコール(PEG) / DDS / 自己組織化 / 高分子構造・物性 / ナノバイオ材料 / 生体関連高分子 / 機能ポ性リマー / 機能性ポリマー / がん標的治療 / 化学療法 / ナノテクノロジー / がん化学療法 / ナノキャリア Less

ユニットPICを起点とする次世代核酸ナノ医薬の創製と生体内バリア突破に向けた挑戦Principal Investigator
- Principal Investigator
  
  宮田完二郎
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
自発分解性ポリペプチドの精密分子設計と免疫原性回避への挑戦Principal Investigator
- Principal Investigator
  
  宮田完二郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Nanostructures with aggregation-induced emission for holistic rheumatoid arthritis treatmentPrincipal Investigator
- Principal Investigator
  
  宮田完二郎
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Tokyo
Pioneering Treatment of Antimicrobial Resistance through Nebulization of Single-Chain Antibody mRNA
- Principal Investigator
  
  内田智士
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo Medical and Dental University
Challenges in dual-targeted nose-to-brain micelles for infected neuron-specific RNA delivery
- Principal Investigator
  
  KANAZAWA Takanori
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokushima
  University of Shizuoka
Development of heteroduplex-oligonucleotide-containing glucose micelle as a blood-brain barrier-crossing nucleic acid drug
- Principal Investigator
  
  桑原宏哉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokyo Medical and Dental University
Development of advanced nanomedicines for brain-targeted oligonucleotide deliveryPrincipal Investigator
- Principal Investigator
  
  Miyata Kanjiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
シンチレーション粒子内包ナノカプセルの構築と放射線療法への展開Principal Investigator
- Principal Investigator
  
  宮田完二郎
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Tokyo
Development of RNA-embedded membrane nanovesicles and their applications as highly functional bioactive mediatorsPrincipal Investigator
- Principal Investigator
  
  Miyata Kanjiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
メッセンジャーＲＮＡを安定化する高分子材料の設計と生体内デリバリーヘの挑戦Principal Investigator
- Principal Investigator
  
  宮田完二郎
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
Targeted oligonucleotide delivery by unit polyion complexesPrincipal Investigator
- Principal Investigator
  
  Miyata Kanjiro
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
Development of heteroduplex oligonucleotide crossing the blood-brain barrier
- Principal Investigator
  
  Yokota Takanori
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Medical and Dental University
ＣＲＩＳＰＲ／Ｃａｓ９封入高分子集合体の構築と生体内デリバリーへの挑戦Principal Investigator
- Principal Investigator
  
  宮田完二郎
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
Development of novel nucleic acid treatment through nano-micelles delivering tumor suppressive microRNA in bladder cancer
- Principal Investigator
  
  ENOKIDA Hideki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Study for elucidating tumor suppressive microRNA that has anti proliferation and prevent metastasis by using metastasis model mouse in bladder cancer
- Principal Investigator
  
  ITESAKO Toshihiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Ｐ－ＢｏｄｙへのｓｉＲＮＡ送達を目指した細胞内ターゲティング高分子キャリアの構築Principal Investigator
- Principal Investigator
  
  宮田完二郎
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
Precise construction of single siRNA-loaded self-assemblies for siRNA deliveryPrincipal Investigator
- Principal Investigator
  
  Miyata Kanjiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
Development of Polymeric Micelles for Brain-Targeted Delivery of Nucleic Acid Drugs to Treat Intractable Neurological Diseases
- Principal Investigator
  
  KATAOKA Kazunori
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  The University of Tokyo
siRNAをビルディングブロックとする超分子構造体の創出と機能開発
- Principal Investigator
  
  片岡一則
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Polymer chemistry
- Research Institution
  The University of Tokyo
Development of systemically injectable siRNA delivery systems by fine-tuning of block copolymers
- Principal Investigator
  
  NISHIYAMA Nobuhiro
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Institute of Technology
  The University of Tokyo
Development of functional polymer-siRNA conjugates for siRNA deliveryPrincipal Investigator
- Principal Investigator
  
  MIYATA Kanjiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo
Development of multifunctional polymeric micelles for systemic siRNA delivery
- Principal Investigator
  
  KATAOKA Kazunori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo
Design of polymeric micelle-based nanodevice with highly modified surfaced and core for gene deliveryPrincipal Investigator
- Principal Investigator
  
  MIYATA Kanjiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Polymer chemistry
- Research Institution
  The University of Tokyo
Polymeric micelle nanocarrier for drug and gene delivery
- Principal Investigator
  
  KATAOKA Kazunori
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

[Book] 核酸医薬・mRNA医薬の製造分析の基礎と基盤技術開発2023
- Author(s)
  宮田完二郎、他
- Total Pages
  290
- Publisher
  シーエムシー・リサーチ
- ISBN
  9784910581347
- Data Source
  KAKENHI-PROJECT-20H00658
[Book] 新規モダリティ医薬品のための新しいＤＤＳ技術と製剤化2023
- Author(s)
  宮田完二郎、他
- Total Pages
  580
- Publisher
  技術情報協会
- ISBN
  9784861049361
- Data Source
  KAKENHI-PROJECT-20H00658
[Book] 医用工学ハンドブック2022
- Author(s)
  佐久間一郎、秋吉一成、津本浩平、宮田完二郎、他
- Total Pages
  544
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437350
- Data Source
  KAKENHI-PROJECT-19F19068
[Book] 医薬品モダリティの特許戦略と技術開発動向2019
- Author(s)
  内藤瑞、宮田完二郎
- Total Pages
  676
- Publisher
  技術情報協会
- ISBN
  9784861047497
- Data Source
  KAKENHI-PROJECT-17H02098
[Book] 刺激応答性高分子ハンドブック2018
- Author(s)
  内藤瑞、吉永直人、宮田完二郎、片岡一則
- Total Pages
  864
- Publisher
  NTS
- ISBN
- Data Source
  KAKENHI-PROJECT-17H02098
[Book] ＤＤＳ先端技術の製剤への応用開発2017
- Author(s)
  宮田完二郎、他
- Total Pages
  492
- Publisher
  技術情報協会
- ISBN
  9784861046636
- Data Source
  KAKENHI-PROJECT-17H02098
[Book] DDS先端技術の製剤への応用開発2017
- Author(s)
  宮田完二郎、他
- Total Pages
  492
- Publisher
  技術情報協会
- ISBN
  9784861046636
- Data Source
  KAKENHI-PROJECT-16F16355
[Book] 核酸医薬の創製と応用展開2016
- Author(s)
  宮田完二郎、他
- Total Pages
  278
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-25282141
[Book] siRNA delivery methods2016
- Author(s)
  H. J. Kim, K. Miyata, et al
- Total Pages
  313
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25282141
[Book] SiRNA delivery methods (Preparation of polyion complex micelles using block copolymers for SiRNA delivery)2016
- Author(s)
  H. -J. Kim, M. Zheng, K. Miyata, K. Kataoka
- Total Pages
  313
- Publisher
  Springer (New York, USA)
- Description
  【発行確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Book] 高分子集合体に基づく核酸デリバリーシステム(核酸医薬の創製と応用展開)2016
- Author(s)
  宮田完二郎、片岡一則
- Pages
  175-184
- Total Pages
  278
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-25000006
[Book] 最新がん薬物療法学－がん薬物療法の最新知見－2014
- Author(s)
  宮田完二郎、片岡一則
- Total Pages
  736
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-25282141
[Book] Non-viral vectors for gene delivery (Advances in Genetics, volume 88)2014
- Author(s)
  Hiroyasu Takemoto, Kanjiro Miyata, et al.
- Total Pages
  271
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-25282141
[Book] Nonviral Vectors for Gene Therapy : Lipid-and Polymer-based Gene Transfer(Bioresponsive polymer-based nucleic acid carriers)2014
- Author(s)
  H. Takemoto, K. Miyata, N. Nishiyama, K. Kataoka
- Total Pages
  409
- Publisher
  Eds., L. Huang, D. Liu, E. Wagner, Academic Press(Massachusetts, USA)
- Description
  【発行確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Book] ここまで広がるドラッグ徐放技術の最前線-古くて新しいドラッグデリバリーシステム(DDS)-2013
- Author(s)
  武元宏泰、宮田完二郎
- Total Pages
  376
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-22700489
[Book] ここまで広がるドラッグ徐放技術の最前線-古くて新しいドラッグデリバリーシステム(DDS)-2013
- Author(s)
  （武元宏泰）、宮田完二郎
- Total Pages
  6
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23350049
[Book] 非経口投与製剤の開発と応用－次世代型医薬品の新規投与形態の開拓を目指して－2013
- Author(s)
  宮田完二郎、片岡一則
- Total Pages
  257
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-25282141
[Book] Tailored Polymer Architectures for Pharmaceutical and Biomedical Applications2013
- Author(s)
  Kanjiro Miyata, R. James Christie, et al.
- Total Pages
  363
- Publisher
  ACS Publication
- Data Source
  KAKENHI-PROJECT-25282141
[Book] 抗がん剤を運ぶシステム:高分子ミセル型DDS、現代化学(464)2009
- Author(s)
  宮田完二郎、片岡一則
- Data Source
  KAKENHI-PROJECT-17016017
[Book] 分子細胞治療2008
- Author(s)
  宮田完二郎, et al
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] Size-tunable PEG-grafted copolymers as a polymeric nanoruler for passive targeting muscle tissues.2022
- Author(s)
  M. Naito, Y. Watanuki, K. Toh, J. Yum, B. S. Kim, K. Taniwaki, S. Ogura, H. Ishida, M. Cho, H. Chaya, K. Miyajima, K. Osada, K. Minegishi, Y. Aoki, Y. Yamasaki, K. Miyata,
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 347 Pages: 607-614
- DOI
  10.1016/j.jconrel.2022.05.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19014, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-20H00658, KAKENHI-PROJECT-23K21412, KAKENHI-PROJECT-23K21857
[Journal Article] 安定なmRNA送達を可能にするシリカナノ粒子設計2022
- Author(s)
  亀川凜平、宮田完二郎
- Journal Title
  
  PHARM STAGE
  
  Volume: 21 Pages: 40-44
- Data Source
  KAKENHI-PROJECT-20H00658
[Journal Article] ポリイオンコンプレックスによるmRNAデリバリーに向けたカチオン性ポリペプチド設計2022
- Author(s)
  内藤瑞、宮田完二郎
- Journal Title
  
  Drug Delivery System
  
  Volume: 37 Pages: 221-228
- Open Access
- Data Source
  KAKENHI-PROJECT-20H00658
[Journal Article] DNA/RNA heteroduplex oligonucleotide technology for regulating lymphocytes in vivo2021
- Author(s)
  Ohyagi Masaki、Nagata Tetsuya、Ihara Kensuke、Yoshida-Tanaka Kie、Nishi Rieko、Miyata Haruka、Abe Aya、Mabuchi Yo、Akazawa Chihiro、Yokota Takanori
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 7344-7344
- DOI
  10.1038/s41467-021-26902-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02909, KAKENHI-PROJECT-21H03328, KAKENHI-PROJECT-18KK0449, KAKENHI-PROJECT-17H06109, KAKENHI-PROJECT-19H01016
[Journal Article] Dynamic Stabilization of Unit Polyion Complexes Incorporating Small Interfering RNA by Fine-Tuning of Cationic Block Length in Two-Branched Poly(ethylene glycol)-<i>b</i>-poly(<scp>l</scp>-lysine)2021
- Author(s)
  Chaya Hiroyuki、Naito Mitsuru、Cho Masaru、Toh Kazuko、Hayashi Kotaro、Fukushima Shigeto、Yamasaki Yuichi、Kataoka Kazunori、Miyata Kanjiro
- Journal Title
  
  Biomacromolecules
  
  Volume: 23 Issue: 1 Pages: 388-397
- DOI
  10.1021/acs.biomac.1c01344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00658
[Journal Article] 核酸医薬のドラッグデリバリー2020
- Author(s)
  内藤瑞、宮田完二郎
- Journal Title
  
  Clinical Neurosicence
  
  Volume: 38 Pages: 314-318
- Data Source
  KAKENHI-PROJECT-17H02098
[Journal Article] Synthetic miR-143 Exhibited an Anti-Cancer Effect via the Downregulation of K-RAS Networks of Renal Cell Cancer Cells In Vitro and In Vivo.2019
- Author(s)
  Takai T、 Tsujino T, Yoshikawa Y, Inamoto T, Sugito N, Kuranaga Y, Heishima K, Soga T, Hayashi K, Miyata K, Kataoka K, Azuma H, Akao Y.
- Journal Title
  
  Mol Ther.
  
  Volume: S1525-0016（１９） Issue: 5 Pages: 30090-5
- DOI
  10.1016/j.ymthe.2019.03.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11033, KAKENHI-PROJECT-17H02098
[Journal Article] Anti-cancer effects of a chemically modified miR-143 on bladder cancer by either systemic or intravesical treatment2019
- Author(s)
  Y. Yoshikawa, K. Taniguchi, T. Tsujino, K. Heishima, T. Inamoto, T. Takai, K. Minami, H. Azuma, K. Miyata, K. Hayashi, K. Kataoka, Y. Akao
- Journal Title
  
  Molecular Therapy: Methods and Clinical Development
  
  Volume: 13 Pages: 290-302
- DOI
  10.1016/j.omtm.2019.02.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02098
[Journal Article] Self-Assembly of siRNA/PEG-b-Catiomer at Integer Molar Ratio into 100 nm-Sized Vesicular Polyion Complexes (siRNAsomes) for RNAi and Codelivery of Cargo Macromolecules2019
- Author(s)
  Kim Beob Soo、Chuanoi Sayan、Suma Tomoya、Anraku Yasutaka、Hayashi Kotaro、Naito Mitsuru、Kim Hyun Jin、Kwon Ick Chan、Miyata Kanjiro、Kishimura Akihiro、Kataoka Kazunori
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 141 Issue: 8 Pages: 3699-3709
- DOI
  10.1021/jacs.8b13641
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20109, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-17K20094, KAKENHI-PROJECT-18K19900, KAKENHI-PROJECT-18K18391
[Journal Article] Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells.2019
- Author(s)
  Y. Yi, H. J. Kim, M. Zheng, P. Mi, M. Naito, B. S. Kim, H. S. Min, K. Hayashi, F. Perche, K. Toh, X. Liu, Y. Mochida, H. Kinoh, H. Cabral, K. Miyata, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 295 Pages: 268-277
- DOI
  10.1016/j.jconrel.2019.01.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K18378, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18K18391, KAKENHI-PROJECT-18K18379
[Journal Article] In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers2019
- Author(s)
  Watanabe Sumiyo、Hayashi Kotaro、Toh Kazuko、Kim Hyun Jin、Liu Xueying、Chaya Hiroyuki、Fukushima Shigeto、Katsushima Keisuke、Kondo Yutaka、Uchida Satoshi、Ogura Satomi、Nomoto Takahiro、et al.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1894-1894
- DOI
  10.1038/s41467-019-09856-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-19K12799, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18391, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-18H02797, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17H04743, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-17H02098
[Journal Article] Smart oligonucleotide delivery by multifunctional block copolymers2019
- Author(s)
  K. Hayashi, K. Miyata
- Journal Title
  
  Material Matters
  
  Volume: 14 Pages: 110-114
- Open Access
- Data Source
  KAKENHI-PROJECT-17H02098
[Journal Article] ドラッグデリバリーの新展開2018
- Author(s)
  宮田完二郎
- Journal Title
  
  Medical Science Digest
  
  Volume: 44 Pages: 584-585
- Data Source
  KAKENHI-PROJECT-17H02098
[Journal Article] Small Delivery Vehicles of siRNA for Enhanced Cancer Targeting2018
- Author(s)
  Kim Hyun Jin、Yi Yu、Kim Ahram、Miyata Kanjiro
- Journal Title
  
  Biomacromolecules
  
  Volume: 19 Issue: 7 Pages: 2377-2390
- DOI
  10.1021/acs.biomac.8b00546
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02098
[Journal Article] 核酸医薬の生体内デリバリー2018
- Author(s)
  内藤瑞、宮田完二郎
- Journal Title
  
  最新医学
  
  Volume: 73 Pages: 751-759
- Data Source
  KAKENHI-PROJECT-17H02098
[Journal Article] Functionalization of silica nanoparticles for nucleic acid delivery2018
- Author(s)
  Kamegawa Rimpei、Naito Mitsuru、Miyata Kanjiro
- Journal Title
  
  Nano Research
  
  Volume: 11 Issue: 10 Pages: 5219-5239
- DOI
  10.1007/s12274-018-2116-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02098
[Journal Article] 核酸医薬の生体内ドラッグデリバリーシステム2018
- Author(s)
  内藤瑞、宮田完二郎
- Journal Title
  
  日本認知症学会誌
  
  Volume: 32 Pages: 607-615
- Data Source
  KAKENHI-PROJECT-17H02098
[Journal Article] Block Copolymer Micelles in Nanomedicine Applications2018
- Author(s)
  Cabral Horacio、Miyata Kanjiro、Osada Kensuke、Kataoka Kazunori
- Journal Title
  
  Chemical Reviews
  
  Volume: 118 Issue: 14 Pages: 6844-6892
- DOI
  10.1021/acs.chemrev.8b00199
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386
[Journal Article] 高分子・無機材料を用いたナノ構造体の創製と核酸デリバリーへの応用2018
- Author(s)
  宮田完二郎
- Journal Title
  
  日本核酸医薬学会誌
  
  Volume: 22 Pages: 13-23
- NAID
  40022468648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02098
[Journal Article] Enhanced intracellular delivery of siRNA by controlling ATP-responsivity of phenylboronic acid-functionalized polyion complex micelles.2018
- Author(s)
  M. Naito, N. Yoshinaga, T. Ishii, A. Matsumoto, Y. Miyahara, K. Miyata, K. Kataoka
- Journal Title
  
  Macromol. Biosci.
  
  Volume: 1 Issue: 1
- DOI
  10.1002/mabi.201700357
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25000006
[Journal Article] Inhibition of PRDM14 expression in pancreatic cancer suppresses cancer stem-like properties and liver metastasis in mice2017
- Author(s)
  C. Moriya, H. Taniguchi, K. Miyata, N. Nishiyama, K. Kataoka, K. Imai
- Journal Title
  
  Carcinogenesis
  
  Volume: 38 Issue: 6 Pages: 638-648
- DOI
  10.1093/carcin/bgx040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297, KAKENHI-PROJECT-17H02098
[Journal Article] Multilayered polyion complexes with dissolvable silica layer covered by controlling densities of cRGD-conjugated PEG chains for cancer-targeted siRNA delivery.2017
- Author(s)
  M. Naito, R. Azuma, H. Takemoto, M. Hori, N. Yoshinaga, S. Osawa, R. Kamegawa, H. -J. Kim, T. Ishii, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  J. Biomater. Sci. Polym.
  
  Volume: 28 Issue: 10-12 Pages: 1109-1123
- DOI
  10.1080/09205063.2017.1301775
- Description
  【掲載確定】 in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-25282141
[Journal Article] Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain2017
- Author(s)
  Anraku Y.、Kuwahara H.、Fukusato Y.、Mizoguchi A.、Ishii T.、Nitta K.、Matsumoto Y.、Toh K.、Miyata K.、Uchida S.、Nishina K.、Osada K.、Itaka K.、Nishiyama N.、Mizusawa H.、Yamasoba T.、Yokota T.、Kataoka K.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 2001-2009
- DOI
  10.1038/s41467-017-00952-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-15H04813, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
[Journal Article] Virus-mimicking chimaeric polymersomes boost targeted cancer siRNA therapy in vivo.2017
- Author(s)
  Y. Zou, M. Zheng, W. Yang, F. Meng, K. Miyata, H. -J. Kim, K. Kataoka, Z. Zhong
- Journal Title
  
  Adv. Mater.
  
  Volume: 29 Issue: 42 Pages: 1703285-1703285
- DOI
  10.1002/adma.201703285
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Journal Article] Recent progress in development of siRNA delivery vehicles for cancer therapy.2016
- Author(s)
  H. -J. Kim, A. Kim, K. Miyata, K. Kataoka
- Journal Title
  
  Adv. Drug Deliv. Rev.
  
  Volume: 104 Pages: 61-77
- DOI
  10.1016/j.addr.2016.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25000006
[Journal Article] Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles2016
- Author(s)
  Yi, Y., Kim, H. J., Mi, P., Zheng, M., Takemoto, H., Toh, K., Kim, B. S., Hayashi, K., Naito, M., Matsumoto, Y., Miyata, K., Kataoka, K.
- Journal Title
  
  J Control Release
  
  Volume: 244 Pages: 247-256
- DOI
  10.1016/j.jconrel.2016.08.041
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
[Journal Article] Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment.2016
- Author(s)
  Katsushima K, Natsume A, Ohka F, Shinjo K, Hatanaka A, Ichimura N, Sato S, Takahashi S, Kimura H, Totoki Y, Shibata T, Naito M, Kim HJ, Miyata K, Kataoka K, Kondo Y.
- Journal Title
  
  Nat Commun.
  
  Volume: 7 Issue: 1 Pages: 13616-13616
- DOI
  10.1038/ncomms13616
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290048, KAKENHI-PROJECT-26430136, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
[Journal Article] Synthetic polyamines to regulate mRNA translation through the preservative binding of eukaryotic initiation factor 4E to the cap structure.2016
- Author(s)
  H. Uchida, K. Itaka, S. Uchida, T. Ishii, T. Suma, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 138 Issue: 5 Pages: 1478-1481
- DOI
  10.1021/jacs.5b11726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
[Journal Article] Influence of RNA strand rigidity on polyion complex formation with block catiomers.2016
- Author(s)
  K. Hayashi, H. Chaya, S. Fukushima, S. Watanabe, H. Takemoto, K. Osada, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  Macromol. Rapid Commun.
  
  Volume: 37 Issue: 6 Pages: 486-493
- DOI
  10.1002/marc.201500661
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16331, KAKENHI-PROJECT-14J10626, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
[Journal Article] Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths.2016
- Author(s)
  T. Ishii, K. Miyata, Y. Anraku, M. Naito, Y. Yi, T. Jinbo, S. Takae, Y. Fukusato, M. Hori, K. Osada, K. Kataoka
- Journal Title
  
  Chem. Commun.
  
  Volume: 52 Pages: 1517-1519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25000006
[Journal Article] リガンド搭載高分子ミセルを用いた組織特異的核酸デリバリー2016
- Author(s)
  内藤瑞樹、宮田完二郎
- Journal Title
  
  日本認知症学会誌 Dementia Japan
  
  Volume: 30 Pages: 2-8
- Data Source
  KAKENHI-PROJECT-25282141
[Journal Article] Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity2016
- Author(s)
  Federico Perche, Yu Yi, Louise Hespel, Peng Mi, Anjaneyulu Dirisala, Horacio Cabral, Kanjiro Miyata, Kazunori Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 90 Pages: 62-71
- DOI
  10.1016/j.biomaterials.2016.02.027
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-14F04352, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
[Journal Article] siRNA-loaded polyion complex micelle decorated with charge-conversional polymer tuned to undergo stepwise response to intra-tumoral and intra-endosomal pHs for exerting enhanced RNAi efficacy.2016
- Author(s)
  M. Tangsangasaksri, H. Takemoto, M. Naito, Y. Maeda, D. Sueyoshi, H. -J. Kim, Y. Miura, J. -Y. Ahn, R. Azuma, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  Biomacromolecules
  
  Volume: 17 Issue: 1 Pages: 246-255
- DOI
  10.1021/acs.biomac.5b01334
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16331, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25282141
[Journal Article] 高分子ナノテクノロジーが切り拓く核酸医薬デリバリー2016
- Author(s)
  宮田完二郎、他
- Journal Title
  
  Drug Delivery System
  
  Volume: 31 Pages: 44-53
- NAID
  130005147215
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25282141
[Journal Article] DNA/RNA Heteroduplex Oligonucleotide for Highly Efficient Gene Silencing.2015
- Author(s)
  Nishina K., Piao W., Yoshida-Tanaka K., Sujino Y., Nishina T., Yamamoto T., Nitta K, Yoshioka K, Kuwahara H., Yasuhara H., Baba T., Ono F., Miyata K, Miyake K., P. Seth P., Low A., Yoshida M., Bennett C.F., Kataoka K., Mizusawa H., Obika S. Yokota T.
- Journal Title
  
  Nature Commun.
  
  Volume: 6 Issue: 1 Pages: 7969-7969
- DOI
  10.1038/ncomms8969
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24249007, KAKENHI-PROJECT-25000006
[Journal Article] Regulated protonation of polyaspartamide derivatives bearing repeated aminoethylene side chains for efficient intracellular siRNA delivery with minimal cytotoxicity2015
- Author(s)
  H. Gao, H. Takemoto, Q. Chen, M. Naito, H. Uchida, X. Liu, K. Miyata, K. Kataoka
- Journal Title
  
  Chemical Communications
  
  Volume: 51 Issue: 15 Pages: 3158-3161
- DOI
  10.1039/c4cc09859e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-15K16331
[Journal Article] Development of Nucleic Acid Delivery System Based on Polymeric Materials2015
- Author(s)
  宮田完二郎
- Journal Title
  
  Drug Delivery System
  
  Volume: 30 Issue: 4 Pages: 363-370
- DOI
  10.2745/dds.30.363
- NAID
  130005116538
- ISSN
  0913-5006, 1881-2732
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-25282141
[Journal Article] 分子レベルの小さな違いを大きな治療成果へとつなぐDDSの開発を目指して2014
- Author(s)
  宮田完二郎
- Journal Title
  
  ドラッグデリバリーシステム
  
  Volume: 29 Pages: 168-169
- NAID
  130004495157
- Data Source
  KAKENHI-PROJECT-25282141
[Journal Article] siRNAを用いたDDSの最新情報2014
- Author(s)
  内藤瑞、宮田完二郎
- Journal Title
  
  医薬ジャーナル
  
  Volume: 50 Pages: 61-65
- Data Source
  KAKENHI-PROJECT-25282141
[Journal Article] Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles2014
- Author(s)
  H. -J. Kim, H. Takemoto, Y. Yi, M. Zheng, Y. Maeda, H. Chaya, K. Hayashi, P. Mi, F. Pittella, R. J. Christie, K. Toh, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 8 Issue: 9 Pages: 8979-8991
- DOI
  10.1021/nn502125h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
[Journal Article] siRNA delivery from triblock copolymer micelles with spatially-ordered compartmants of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core2014
- Author(s)
  Hyun Jin Kim, Kanjiro Miyata, Takahiro Nomoto, Meng Zheng, Ahram Kim, Xueying Liu, Horacio Cabral, R. James Christie, Nobuhiro Nishiyama, Kazunori Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 15 Pages: 4548-4556
- DOI
  10.1016/j.biomaterials.2014.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors2014
- Author(s)
  Y. Oe, R. J. Christie, M. Naito, S. A. Low, S. Fukushima, K. Toh, Y. Miura, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 27 Pages: 7887-7895
- DOI
  10.1016/j.biomaterials.2014.05.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
[Journal Article] Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors2014
- Author(s)
  Dirisala A, Osada K, Chen Q, Tockary TA, Machitani K, Osawa S, Liu X, Ishii T, Miyata K, Oba M, Uchida S, Itaka K, Kataoka K
- Journal Title
  
  Biomaterials
  
  Volume: 35(20) Issue: 20 Pages: 5359-5368
- DOI
  10.1016/j.biomaterials.2014.03.037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
[Journal Article] 高分子ナノテクノロジーを利用した核酸医薬デリバリー2014
- Author(s)
  宮田完二郎
- Journal Title
  
  BIO Clinica
  
  Volume: 29 Pages: 23-27
- Data Source
  KAKENHI-PROJECT-25282141
[Journal Article] Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer2014
- Author(s)
  Hyun Jin Kim, Takehiko Ishii, Meng Zheng, Sumiyo Watanabe, Kazuko Toh, Yu Matsumoto, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka
- Journal Title
  
  Drug Delivery and Translational Research
  
  Volume: 4 Issue: 1 Pages: 50-60
- DOI
  10.1007/s13346-013-0175-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
[Journal Article] Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles2014
- Author(s)
  F. Pittella, N. Nishiyama, et al.
- Journal Title
  
  J. Control. Release
  
  Volume: 178 Pages: 18-24
- DOI
  10.1016/j.jconrel.2014.01.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer2014
- Author(s)
  T. Nomoto, S. Fukushima, M. Kumagai, K. Machitani, Arnida, Y. Matsumoto, M. Oba, K. Miyata, K. Osada, N. Nishiyama, K. Kataoka
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 3545-3545
- DOI
  10.1038/ncomms4545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J08266, KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25670010
[Journal Article] Modulated protonation of side chain aminoethylene repeats in N-substituted polyaspartamides promotes mRNA transfection2014
- Author(s)
  H. Uchida, K. Itaka, T. Nomoto, T. ishii, T. Suma, M. Ikegami, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 Issue: 35 Pages: 12396-12405
- DOI
  10.1021/ja506194z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006
[Journal Article] Nanodevices for Studying Nano-pathophysiology2014
- Author(s)
  *Horacio Cabral, Kanjiro Miyata, *Akihiro Kishimura,
- Journal Title
  
  Advanced Drug Delivery Reviews
  
  Volume: 74 Pages: 35-52
- DOI
  10.1016/j.addr.2014.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25107709, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-25620124, KAKENHI-PROJECT-26288082
[Journal Article] Fine-tuning of charge-conversion polymer structure for efficient endosomal escape of siRNA-loaded calcium phosphate hybrid micelles2014
- Author(s)
  Y. Maeda, F. Pittella, T. Nomoto, H. Takemoto, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  Macromol. Rapid Commun.
  
  Volume: 35 Issue: 13 Pages: 1211-1215
- DOI
  10.1002/marc.201400049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006
[Journal Article] Acidic pH-Responsive siRNA Conjugate for Reversible Carrier Stability and Accelerated Endosoraal Escape with Reduced IFNα -Associated Immune Response2013
- Author(s)
  Hiroyasu Takemoto, Kanjiro Miyata, Shota Hattori, Takehiko Ishii, Toraoya Suma, Satoshi Uchida, Nobuhiro Nishiyama and Kazunori Kataoka
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 52 Issue: 24 Pages: 6218-6221
- DOI
  10.1002/anie.201300178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08644, KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23390009
[Journal Article] 微小な化学構造の違いに基づき低毒性/高効率核酸送達を実現する高分子ナノ材料設計2013
- Author(s)
  宮田完二郎
- Journal Title
  
  バイオマテリアル-生体材料-
  
  Volume: 31 Pages: 26-34
- Data Source
  KAKENHI-PROJECT-22700489
[Journal Article] Transcription factor YYI contributes to tumor growth by stabilizing hypoxia fact or HIF-lα in a p53-independent manner.2013
- Author(s)
  S. Wu, N. Nishiyama, et al.
- Journal Title
  
  Cancer Res.
  
  Volume: 73 Issue: 6 Pages: 1787-1799
- DOI
  10.1158/0008-5472.can-12-0366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051
[Journal Article] Silica nanogelling of environment-responsive PEGylated polyplexes for enhanced stability and intracellular delivery of siRNA2013
- Author(s)
  N. Gouda, K. Miyata
- Journal Title
  
  Biomaterials
  
  Volume: 34 Issue: 2 Pages: 562-570
- DOI
  10.1016/j.biomaterials.2012.09.077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23685037
[Journal Article] Rational design of smart supramolecular assemblies for gene delivery : Chemical challenges in the creation of artificial viruses2012
- Author(s)
  K. Miyata, N. Nishiyama, K. Kataoka
- Journal Title
  
  Chem. Soc. Rev
  
  Volume: 41(7) Issue: 7 Pages: 2562-2574
- DOI
  10.1039/c1cs15258k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489
[Journal Article] Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG2012
- Author(s)
  T. Suma, K. Miyata
- Journal Title
  
  ACS Nano
  
  Volume: 6 Issue: 8 Pages: 6693-6705
- DOI
  10.1021/nn301164a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-24700476
[Journal Article] Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain2012
- Author(s)
  T.Suma, N.Nishiyama, et al
- Journal Title
  
  Biomaterials
  
  Volume: 33 Issue: 9 Pages: 2770-2779
- DOI
  10.1016/j.biomaterials.2011.12.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
[Journal Article] A phenylboronate-functionalized polyion complex micelle for ATP-triggered release of siRNA2012
- Author(s)
  M. Naito, K. Miyata
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: 51 Issue: 43 Pages: 10751-10755
- DOI
  10.1002/anie.201203360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049
[Journal Article] Accelerated Polymer-Polymer Click Conjugation by Freeze-Thaw Treatment2012
- Author(s)
  Hiroyasu Takeraoto, Kanjiro Miyata, Shota Hattori, Shigehito Osawa, Nobuhiro Nishiyama, Kazunori Kataoka
- Journal Title
  
  Bioconjugate Chemsitry
  
  Volume: 23 Issue: 8 Pages: 1503-1506
- DOI
  10.1021/bc300182y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08644, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23390009
[Journal Article] Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles2012
- Author(s)
  F. Pittella, K. Miyata
- Journal Title
  
  J. Control.Release
  
  Volume: 161 Issue: 3 Pages: 868-874
- DOI
  10.1016/j.jconrel.2012.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-22890196, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659411
[Journal Article] Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection2012
- Author(s)
  R. J. Christie, Y. Matsumoto, K. Miyata, T. Nomoto, S. Fukushima, K. Osada, J. Halnaut, F. Pittella, H. -J. Kim, N. Nishiyama, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 6(6) Issue: 6 Pages: 5174-5189
- DOI
  10.1021/nn300942b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08266, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043
[Journal Article] Impact of polyplex micelles installed with cyclic RGD peptide as ligand on gene delivery to vascular lesions2012
- Author(s)
  Kagaya H, Koyama H, Miyata T
- Journal Title
  
  Gene Therapy
  
  Volume: 19 Issue: 1 Pages: 61-69
- DOI
  10.1038/gt.2011.74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390244, KAKENHI-PROJECT-22390245, KAKENHI-PROJECT-22800013, KAKENHI-PROJECT-23350049
[Journal Article] Polymeric micelles for nano-scale drugdelivery2011
- Author(s)
  K. Miyata, R. J. Christie, K. Kataoka
- Journal Title
  
  React. Funct. Polym
  
  Volume: 71 Issue: 3 Pages: 227-234
- DOI
  10.1016/j.reactfunctpolym.2010.10.009
- Data Source
  KAKENHI-PROJECT-22700489
[Journal Article] Effect of polymer structure on micelles formed between siRNA and cationic block copolymer Comprising thiols and amidines2011
- Author(s)
  R. J. Christie, K. Miyata, Y. Matsumoto, T. Nomoto, D. Menasco, T.-C. Lai, M. Pennisi, K. Osada, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
- Journal Title
  
  Biomacromolecules
  
  Volume: 12(9) Issue: 9 Pages: 3174-3185
- DOI
  10.1021/bm2006714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043
[Journal Article] Effect of integrin targeting and PEG shielding on polyplex micelle internalization studied by live-cell imaging2011
- Author(s)
  F.M.Konig, Y.Vachutinsky, M.Oba, K.Miyata, N.Nishiyama, K.Kataoka, C.Brauchle, N.Ruthardt
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 151(2) Issue: 3 Pages: 104-109
- DOI
  10.1016/j.jconrel.2011.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689024, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
[Journal Article] Odd-even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles2011
- Author(s)
  H.Uchida, N.Nishiyama, et al
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: 133 Issue: 39 Pages: 15524-15532
- DOI
  10.1021/ja204466y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
[Journal Article] Combination of Chondroitin Sulfate and Polyplex Micelles from Poly(ethylene glycol)-poly{N'-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} Block Copolymer for Prolonged In Vivo Gene Transfection with Reduced Toxicity2011
- Author(s)
  Uchida S, Itaka K, Chen Q, Osada K, Miyata K, Ishii T, Harada-Shiba M, Kataoka K
- Journal Title
  
  J Control Release
  
  Volume: 2 Issue: 2 Pages: 296-302
- DOI
  10.1016/j.jconrel.2011.04.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300177, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049
[Journal Article] In situ quantitative monitoring of polyplexes and polyplex Micelles in the blood circulation using intravital real-time confocal laser scanning microscopy2011
- Author(s)
  T.Nomoto, Y.Matsumoto, K.Miyata, M.Oba, S.Fukushima, N.Nishiyama, T.Yamasoba, K.Kataoka
- Journal Title
  
  J.Control.Release
  
  Volume: 151(2) Issue: 2 Pages: 104-109
- DOI
  10.1016/j.jconrel.2011.02.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08266, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
[Journal Article] PEG-detachable cationic polyaspartamide detivatives bearing stearoyl moieties for systemic siRNA delivery toward subcutaneous BxPC3 pancreatic tumor2011
- Author(s)
  H.-J.Kim, N.Nishiyama, et al
- Journal Title
  
  J.Drug Target.
  
  Volume: 20 Issue: 1 Pages: 33-42
- DOI
  10.3109/1061186x.2011.632010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043
[Journal Article] Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity2011
- Author(s)
  F. Pittella, M. Zhang, Y. Lee, H.-J. Kim, T. Tockary, K. Osada, T. Ishii, K. Miyata, N. Nishiyama
- Journal Title
  
  Biomaterials
  
  Volume: 32(11) Issue: 11 Pages: 3106-3114
- DOI
  10.1016/j.biomaterials.2010.12.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23390009
[Journal Article] Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown2010
- Author(s)
  H.-J. Kim, A. Ishii, K. Miyata, Y. Lee, S. Wu, M. Oba, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 145(2) Issue: 2 Pages: 141-148
- DOI
  10.1016/j.jconrel.2010.03.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489
[Journal Article] siRNA-grafted polymer for polyion complex(PIC)-based siRNA delivery : Enhancement of PIC stability and gene silencing efficiency2010
- Author(s)
  H. Takemoto, A. Ishii, K. Miyata, M. Nakanishi, M. Oba, T. Ishii, Y. Yamasaki, N. Nishiyama, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 31(31) Issue: 31 Pages: 8097-8105
- DOI
  10.1016/j.biomaterials.2010.07.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489
[Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA2010
- Author(s)
  K.Miyata, K.Kataoka, et al
- Journal Title
  
  Biomaterials Vol.31
  
  Pages: 4764-4770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240046
[Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA.2010
- Author(s)
  K.Miyata, K.Kataoka, et al.
- Journal Title
  
  Biomaterials
  
  Volume: 31 Pages: 4764-4770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240046
[Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA2010
- Author(s)
  K.Miyata, K.Kataoka, et al.
- Journal Title
  
  Biomaterials 31
  
  Pages: 4764-4770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010
- Author(s)
  M. Oba, Y. Vachutinsky, K. Miyata, M.R. Kano, S. Ikeda, N. Nishiyama, K. Itaka, K. Miyazono, H. Koyama, K. Kataoka
- Journal Title
  
  Mol. Pharm 7(2)
  
  Pages: 501-509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article]2008
- Author(s)
  Y. Lee, K. Miyata, M. Oba, T. Ishii, S. Fukushima, M. Han, H. Koyama, N. Nishiyama, K. Kataoka
- Journal Title
  
  Angew. Chem. Int. Ed. 47
  
  Pages: 5163-5166
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] Polyplexes from poly (aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplifiedt ransfection and negligible cytotoxicity2008
- Author(s)
  Miyata, K. Kataoka, et.al.
- Journal Title
  
  J. Am. Chem. Soc. 130
  
  Pages: 16287-16294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Charge-conversion ternary polyplex with endosome disruption moiety : A technique for efficient and safe gene delivery2008
- Author(s)
  Y. Lee, K. Miyata, et.al.
- Journal Title
  
  Angewante Chemie International Edition 47
  
  Pages: 5163-5166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article]2008
- Author(s)
  K. Miyata, M. Oba, M. Nakanishi, S. Fukushima, Y. Yamasaki, H. Koyama, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc. 130
  
  Pages: 16287-16294
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] Polyplexes from poly(aspartamide) bearing 1, 2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity2008
- Author(s)
  K. Miyata, et.al.
- Journal Title
  
  Journal of the American Chemical Society 130
  
  Pages: 16287-16294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking2008
- Author(s)
  M. Oba, K. Aoyagi, K. Miyata, Y. Matsumoto, K. Itaka, N. Nishiyama, Y. Yamasaki, H. Koyama, K. Kataoka
- Journal Title
  
  Mol. Pharm. 5(6)
  
  Pages: 1080-1092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor2008
- Author(s)
  K. Miyata, M. Oba, M.R. Kano, S. Fukushima, Y. Vachutinsky, M. Han, H. Koyama, K. Miyazono, N. Nishiyama, K. Kataoka
- Journal Title
  
  Pharm. Res. 25(12)
  
  Pages: 2924-2936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor tissue2008
- Author(s)
  K. Miyata, K. Kataoka, et.al.
- Journal Title
  
  Pharm. Res. 25
  
  Pages: 2924-2936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Polyplexes from poly(aspartamide) bearing 1, 2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity2008
- Author(s)
  K. Miyata, M. Oba, M. Nakanishi, S. Fukushima, Y. Yamasaki, H. Koyama, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc. 130(48)
  
  Pages: 16287-16294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor2008
- Author(s)
  K. Miyata, et.al.
- Journal Title
  
  Pharmaceutical Research 25
  
  Pages: 2924-2936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] Polyplexes from poly(aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity.2008
- Author(s)
  K. Miyata, K. Kataoka. et al.
- Journal Title
  
  J. Am. Chem. Soc. 130
  
  Pages: 16287-16294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240046
[Journal Article] Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor tissue.2008
- Author(s)
  K. Miyata,K. Kataoka, et al.
- Journal Title
  
  Pharm. Res. 25
  
  Pages: 2924-2936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240046
[Journal Article]2008
- Author(s)
  M. Oba, K. Aoyagi, K. Miyata, Matsumoto, K. Itaka, N. Nishiyama, Yamasaki, H. Koyama, K. Kataoka
- Journal Title
  
  Mol. Pharm. 5
  
  Pages: 1080-1092
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article]2008
- Author(s)
  S. Takae, K. Miyata, M. Oba, T. Ishii, N. Nishiyama, K. Itaka, Y. Yamasaki, H. Koyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc. 130
  
  Pages: 6001-6009
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article]2008
- Author(s)
  K. Miyata, M. Oba, M. R. Kano, S. Fukushima, Y. Vachutinsky, M. Han, H. Koyama, K. Miyazono, N. Nishiyama, K. Kataoka
- Journal Title
  
  Pharm. Res. 25
  
  Pages: 2924-2936
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors2008
- Author(s)
  S. Takae, K. Miyata, et.al.
- Journal Title
  
  Journal of the American Chemical Society 130
  
  Pages: 6001-6009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking2008
- Author(s)
  M. Oba, K. Aoyagi, K. Miyata, et.al.
- Journal Title
  
  Molecular Pharmaceutics 5
  
  Pages: 1080-1092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] DDS・遺伝子治療とナノテクノロジー2008
- Author(s)
  宮田完二郎、片岡一則
- Journal Title
  
  分子細胞治療 7
  
  Pages: 26-33
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy2007
- Author(s)
  K. Miyata, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
- Journal Title
  
  J. Control. Release 122(3)
  
  Pages: 252-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article]2007
- Author(s)
  K. Itaka, S. Ohba, K. Miyata, H. Kawaguchi, K. Nakamura, T. Takato, U. -I. Chung, K. Kataoka
- Journal Title
  
  Mol Ther. 15
  
  Pages: 1655-1662
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article]2007
- Author(s)
  M. Han, Y. Bae, N. Nishiyama, K. Miyata, M. Oba, K. Kataoka
- Journal Title
  
  J. Control. Release 121
  
  Pages: 38-48
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection effocacy.2007
- Author(s)
  K. Miyata, K. Kataoka, et. al.
- Journal Title
  
  J.Control. Release 122
  
  Pages: 252-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles2007
- Author(s)
  K. Itaka, S. Ohba, K. Miyata, H. Kawaguchi, K. Nakamura, T. Takato, U. Chung, K. Kataoka
- Journal Title
  
  Molecular Therapy 15
  
  Pages: 1655-1662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies2007
- Author(s)
  M. Han, Y. Bae, N. Nishiyama, K. Miyata, M. Oba, K. Kataoka
- Journal Title
  
  J. Control. Release 121
  
  Pages: 38-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high・transfection efficacy2007
- Author(s)
  K. Miyata, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
- Journal Title
  
  J. Control. Release 122
  
  Pages: 252-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article]2007
- Author(s)
  K. Miyata, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
- Journal Title
  
  J. Control. Release 122
  
  Pages: 252-260
- Data Source
  KAKENHI-PROJECT-19750088
[Journal Article] Freeze-dried formulations for in vivo gene delivery of PEGylated polyplex micelle with disulfide crosslinked cores to the liver2006
- Author(s)
  Miyata, K., Kataoka, K.et al.
- Journal Title
  
  Journal of Controlled Release 109(1-3)
  
  Pages: 15-23
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles
- Author(s)
  Y. Vachutinsky, M. Oba, K. Miyata, S. Hiki, M.R. Kano, N. Nishiyama, H. Koyama, K. Miyazono, K. Kataoka
- Journal Title
  
  J. Control. Release (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Patent] 化学修飾型 1 本鎖核酸を構成成分とする中空粒子2019
- Inventor(s)
  宮田完二郎、他４名
- Industrial Property Rights Holder
  宮田完二郎、他４名
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18K19900
[Patent] 核酸登載ユニット型ポリイオンコンプレックス2017
- Inventor(s)
  キムヒョンジン、宮田完二郎、渡邉秀美代、藤加珠子、福島重人、片岡一則、林光太朗
- Industrial Property Rights Holder
  公益財団法人川崎市産業振興財団、国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-166735
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] 核酸搭載ユニット型ポリイオンコンプレックス2017
- Inventor(s)
  宮田完二郎、他
- Industrial Property Rights Holder
  東京大学、他
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17H02098
[Patent] 温度感受性重合体を用いた核酸の送達用ミセル組成物およびその製造方法2016
- Inventor(s)
  片岡一則、安楽泰孝、宮田完二郎、メンジェン、大澤重仁
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2016-05-20
- Overseas
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法2014
- Inventor(s)
  片岡一則, 安楽泰孝, 西山伸宏, 宮田完二郎, 石井武彦, 松本有, 福里優, 溝口明祐, 横田隆徳, 桑原宏哉, 仁科一隆, 水澤英洋
- Industrial Property Rights Holder
  国立大学法人東京大学、国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-096935
- Filing Date
  2014-05-08
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法2014
- Inventor(s)
  片岡一則、安楽泰孝、西山伸宏、宮田完二郎、石井武彦、松本有、溝口明祐、横田隆徳、桑原宏哉、仁科一隆、水澤英洋
- Industrial Property Rights Holder
  国立大学法人東京大学国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-11-21
- Acquisition Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法2013
- Inventor(s)
  片岡一則、安楽泰孝、西山伸宏、宮田完二郎、石井武彦、松本有、福里優、溝口明祐、横田隆徳、桑原宏哉、仁科一隆、水澤英洋
- Industrial Property Rights Holder
  国立大学法人東京大学、国立大学法人東京医科歯科大
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-22
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] 核酸デリバリー用ユニット構造型医薬組成物2013
- Inventor(s)
  片岡一則、宮田完二郎、西山伸宏、長田健介、渡邊秀美代、福島重人、茶谷洋行、武元宏泰、加藤泰己
- Industrial Property Rights Holder
  国立大学法人東京大学、ナノキャリア株式会社
- Filing Date
  2013-04-30
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] 核酸デリバリー用ユニット構造体2012
- Inventor(s)
  片岡一則、宮田完二郎、西山伸宏、長田健介、加藤泰己､他4名
- Industrial Property Rights Holder
  片岡一則、宮田完二郎、西山伸宏、長田健介、加藤泰己､他4名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-102841
- Filing Date
  2012-04-27
- Data Source
  KAKENHI-PROJECT-23350049
[Patent] 粒子組成物および該粒子組成物を用いた医薬組成物2012
- Inventor(s)
  片岡一則、ロナルド・ジェイムズ・クリスティ(Ronald James Christie)、西山伸宏、宮田完二郎、福島重人、松本有、野本貴
- Industrial Property Rights Holder
  国立大学法人東京大学、ナノキャリア株式会社
- Filing Date
  2012-01-16
- Overseas
- Data Source
  KAKENHI-PROJECT-23350049
[Patent] 物質内包ベクシル及びその製造方法2011
- Inventor(s)
  片岡一則、岸村顕広、安楽泰孝、宮田完二郎、大庭誠、須磨知也、サヤン・チュアノイ(Sayan Chuanoi)
- Industrial Property Rights Holder
  独立行政法人科学技術振興機構
- Filing Date
  2011-05-23
- Data Source
  KAKENHI-PROJECT-23350049
[Patent] カチオン性のポリ(アミノ酸)およびその使用2009
- Inventor(s)
  西山伸宏, 片岡一則, 宮田完二郎, 石井武彦, 呉寿栄, キムヒュンジン
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Number
  2009-031799
- Filing Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-17016017
[Presentation] 核酸医薬デリバリーに向けた高分子ナノ医薬の設計2023
- Author(s)
  宮田完二郎
- Organizer
  令和4年度創薬サイエンス部門シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 高分子材料の精密構造設計に基づく核酸デリバリー2023
- Author(s)
  宮田完二郎
- Organizer
  北海道DDS研究会公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] がんを標的とする核酸デリバリーの現状と課題2023
- Author(s)
  宮田完二郎
- Organizer
  EPOC/CPOTセミナー DDSの最前線
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 核酸デリバリーに向けた高分子ナノ医薬の精密構造設計2022
- Author(s)
  宮田完二郎
- Organizer
  ニューモダリティと有機合成化学」研究部会第 8 回勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 血中滞留性向上を目指した１分子siRNA内包ユニットポリイオンコンプレックスの設計2022
- Author(s)
  内藤瑞, 茶谷洋行, 張賢, 藤加珠子, 林光太朗, 福島重人, 山崎裕一, 片岡一則, 宮田完二郎
- Organizer
  第27回創剤フォーラム若手研究会
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] リガンド導入数を制御可能なグラフトコポリマーの合成および細胞取り込み挙動の評価2022
- Author(s)
  張賢, 木下動, 内藤瑞, 綿貫裕介, ヨムジョンミン, キムボブス, 山﨑裕一, 宮田完二郎
- Organizer
  第71回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 核酸医薬を届ける・留まらせる高分子ナノ医薬2022
- Author(s)
  宮田完二郎
- Organizer
  第28回日本遺伝子細胞治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 1分子核酸医薬内包ユニットポリイオンコンプレックスの血中滞留性向上を指向したブロック共重合体のカチオン鎖長設計2022
- Author(s)
  内藤瑞, 茶谷洋行, 張賢, 藤加珠子, 林光太朗, 福島重人, 山﨑裕一, 片岡一則, 宮田完二郎
- Organizer
  第71回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 標的組織に送り届ける、留まらせる高分子ナノ医薬2022
- Author(s)
  宮田完二郎
- Organizer
  日本核酸医薬学会第7回年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 血中滞留性向上を目指した1分子siRNA内包ユニットポリイオンコンプレックスの設計2022
- Author(s)
  内藤瑞, 茶谷洋行, 張賢, 藤加珠子, 林光太朗, 福島重人, 山崎裕一, 片岡一則, 宮田完二郎
- Organizer
  日本核酸医薬学会第7回年会
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 1分子核酸内包ユニットポリイオンコンプレックスの血中滞留性向上を指向した分子設計2022
- Author(s)
  内藤瑞, 茶谷洋行, 張賢, 藤加珠子, 林光太朗, 福島重人, 片岡一則, 宮田完二郎
- Organizer
  第71回高分子討論会
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 核酸デリバリーに向けた高分子ナノ医薬の設計2022
- Author(s)
  宮田完二郎
- Organizer
  第38回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 超微小ナノ医薬「ユニットポリイオンコンプレックス」による核酸医薬デリバリー2022
- Author(s)
  宮田完二郎
- Organizer
  第63回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 高分子化学によるナノ構造体設計と核酸DDSへの展開2022
- Author(s)
  宮田完二郎
- Organizer
  第27回創剤フォーラム若手研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] Polymeric nanomedicines for advanced nucleic acid delivery2022
- Author(s)
  K. Miyata
- Organizer
  2022 International Graduate Symposium on Biopharmaceuticals
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] Polymeric nanomedicines for advanced nucleic acid delivery2022
- Author(s)
  K. Miyata, M. Naito, H. J. Kim
- Organizer
  2022 Annual Meeting & International Conference of the KSPST
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 高分子材料設計による先端的核酸医薬デリバリー2021
- Author(s)
  宮田完二郎
- Organizer
  CEMS Topical Meeting Online
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 核酸医薬の実用化に資するナノマシン：送達困難な組織への核酸医薬デリバリー2021
- Author(s)
  宮田完二郎
- Organizer
  COINS seminar ♯58
- Invited
- Data Source
  KAKENHI-PROJECT-19F19068
[Presentation] 1分子核酸内包キャリアの血中滞留性向上を指向したブロック共重合体の精密設計2021
- Author(s)
  茶谷洋行, 内藤瑞, 張賢, 藤加珠子, キムボブス, キムヒョンジン, 林光太朗, 福島重人, 片岡一則, 宮田完二郎
- Organizer
  第70回高分子討論会
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 送達困難とされる生体組織への核酸医薬デリバリー2021
- Author(s)
  宮田完二郎
- Organizer
  CPhI Japan 2021
- Invited
- Data Source
  KAKENHI-PROJECT-19F19068
[Presentation] 高分子材料の精密設計による核酸デリバリー2021
- Author(s)
  宮田完二郎
- Organizer
  第9回Chem-Bio Joint Seminar 2021
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 核酸医薬の実用化に資するナノマシン：送達困難な組織への核酸医薬デリバリー2021
- Author(s)
  宮田完二郎
- Organizer
  COINS seminar ♯58
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] Prolonged blood circulation of siRNA-loaded ultrasmall polymeric nanocarriers by fine-tuning of oligonucleotide structures2021
- Author(s)
  H. Chaya, M. Naito, K. Toh, B. S. Kim, K. Hayashi, S. Fukushima, K. Kataoka, K. Miyata
- Organizer
  The 48th Annual Meeting of the Controlled Release Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 送達困難とされる生体組織への核酸医薬デリバリー2021
- Author(s)
  宮田完二郎
- Organizer
  CPhI Japan 2021
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 血中動態の改善を指向した化学修飾核酸siRNA封入ユニットポリイオンコンプレックスの構築2021
- Author(s)
  茶谷洋行, 内藤瑞, 藤加珠子, 林光太朗, 福島重人, 片岡一則, 宮田完二郎
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 核酸医薬の体内分布を制御する高分子材料設計2021
- Author(s)
  宮田完二郎
- Organizer
  日本薬物動態学会第36回年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 核酸医薬デリバリーに資する高分子材料の設計2021
- Author(s)
  宮田完二郎
- Organizer
  第22回ケムステVシンポ「次世代DDSナノキャリア」
- Invited
- Data Source
  KAKENHI-PROJECT-20H00658
[Presentation] 難治がんに薬を送り届ける、やさしいナノ医療2020
- Author(s)
  宮田完二郎
- Organizer
  第7回COINSシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19F19068
[Presentation] 送達困難とされる臓器・組織への核酸医薬デリバリーを目指して2020
- Author(s)
  宮田完二郎
- Organizer
  核酸創薬研究部門第2回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] 抗体リガンド搭載高分子ミセルの構築とがんへの核酸医薬デリバリー2019
- Author(s)
  宮田完二郎, ミンヒョンス, キムヒョンジン, 内藤瑞, 松村保広, 片岡一則
- Organizer
  日本核酸医薬学会第4回年会
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] アンチセンス核酸を膜成分とするベシクル型ポリイオンコンプレックス(ASOsome)の構築とデリバリーへの展開2019
- Author(s)
  宮田完二郎, キムボブス, 内藤瑞, キムヒョンジン, 片岡一則, 岸村顕広
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PROJECT-18K19900
[Presentation] Development of thiol-crosslinked micelle for systemic delivery of antisense oligonucleotide to treat brain diseases2019
- Author(s)
  H. -J. Kim, H. -S. Min, K. Katsushima, Y. Kondo, K. Miyata, K. Kataoka
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] siRNA送達に向けたカチオン性ポリアミノ酸の検討2019
- Author(s)
  林光太朗, 福島重人, 西山伸宏, 宮田完二郎, 片岡一則
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] siRNAsome: A self-assembled vesicular architecture formed from siRNAs and PEGylated block catiomers2019
- Author(s)
  B. S. Kim, S. Chuanoi, Y. Anraku, K. Miyata, A. Kishimura, K. Kataoka
- Organizer
  6th International Conference on Multifunctional, Hybrid and Nanomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18115
[Presentation] ASOball: pulmonary delivery of antisense oligonulceotides-based conjugates for enhanced gene silencing2019
- Author(s)
  B. S. Kim, S. Osawa, M. Naito, S. Ogura, H. J. Kim, K. Miyata
- Organizer
  The 6th COINS Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18115
[Presentation] Nanopharmaceutical design to break through biological barriers2019
- Author(s)
  K. Miyata
- Organizer
  LINK-J/UCSD Life Science Symposium 2019
- Invited
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] Fabrication of vesicular polyion complexes comprising oligonucleotides as a membrane component2019
- Author(s)
  K. Miyata, B. S. Kim, S. Chuanoi, M. Naito, H. J. Kim, A. Kishimura, K. Kataoka
- Organizer
  第68回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K19900
[Presentation] リガンド搭載高分子ミセルの構築と核酸医薬デリバリーへの展開2019
- Author(s)
  宮田完二郎, ミンヒョンス, イウ, 内藤瑞, キムヒョンジン, 片岡一則
- Organizer
  第67回高分子討論会
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] siRNAsomes: a vesicular polyion complex comprising siRNA-intercalated membrane for high loading and efficient delivery of siRNA2019
- Author(s)
  K. Miyata, B. S. Kim, S. Chuanoi, Y. Anraku, M. Naito, H. J. Kim, A. Kishimura, K. Kataoka
- Organizer
  19th Symposium for Gene and Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19900
[Presentation] 1分子核酸を内包する極小核酸キャリアの構築と難治がん治療への展開2019
- Author(s)
  宮田完二郎, 渡邉秀美代, 林光太朗, 藤加珠子, キムヒョンジン, 茶谷洋行, 福島重人, 内藤瑞, 片岡一則
- Organizer
  第41回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] ASOsome: a Polyion complex vesicle possessing antisense oligonucleotides (ASO)-intercalated membrane2019
- Author(s)
  B. S. Kim, A. Kishimura, K. Kataoka, K. Miyata
- Organizer
  The 16th Pacific Polymer Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19900
[Presentation] 極小サイズのsiRNA送達システムの構築とそのすい臓ガンモデルへの効果2019
- Author(s)
  林光太朗, 福島重人, 藤加珠子, 西山伸宏, 宮田完二郎, 片岡一則
- Organizer
  第35回日本DDS学会
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] 高分子材料を用いたドラッグデリバリーのこれまでとこれから2019
- Author(s)
  宮田完二郎
- Organizer
  第34回高分子学会関東支部茨城地区若手の会交流会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] Smart oligonucleotide delivery by polymer nanotechnology2019
- Author(s)
  K. Miyata
- Organizer
  The 35th International Conference of Photopolymer Science and Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] 高分子材料の精密設計による核酸デリバリー2019
- Author(s)
  宮田完二郎
- Organizer
  第14回ナノ・バイオメディカル学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] Fabrication of vesicular polyion complexes comprising oligonucleotide-intercalated membrane for enhanced oligonucleotide delivery2019
- Author(s)
  宮田完二郎, キムボブス, 内藤瑞, キムヒョンジン, 片岡一則, 岸村顕広
- Organizer
  日本核酸医薬学会第5回年会
- Data Source
  KAKENHI-PROJECT-18K19900
[Presentation] iRNAsome: A self-assembled vesicular architecture formed from siRNAs and PEGylated block catiomers2019
- Author(s)
  B. S. Kim, S. Chuanoi, Y. Anraku, K. Miyata, A. Kishimura, K. Kataoka
- Organizer
  6th International Conference on Multifunctional, Hybrid and Nanomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18115
[Presentation] 送達困難な標的組織への核酸医薬デリバリー2019
- Author(s)
  宮田完二郎
- Organizer
  第35回日本DDS学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] Thermoresponsive polyion complex micelles for systemic delivery of antisense oligonucleotides2019
- Author(s)
  B. S. Kim, S. Osawa, K. Kataoka, K. Miyata
- Organizer
  Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18115
[Presentation] siRNAsome: A self-assembled vesicular architecture formed from siRNAs and PEGylated block catiomers2019
- Author(s)
  B. S. Kim, S. Chuanoi, Y. Anraku, K. Miyata, A. Kishimura, K. Kataoka
- Organizer
  6th International Conference on Multifunctional, Hybrid and Nanomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19900
[Presentation] 送達困難とされる臓器・組織への核酸デリバリー2019
- Author(s)
  宮田完二郎
- Organizer
  日本核酸医薬学会DDS部会主催合同サテライトシンポジウム2019
- Invited
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] ASOsome: a Polyion complex vesicle possessing antisense oligonucleotides (ASO)-intercalated membrane2019
- Author(s)
  B. S. Kim, A. Kishimura, K. Kataoka, K. Miyata
- Organizer
  The 16th Pacific Polymer Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18115
[Presentation] Y-shaped block catiomer (YBC) forms "Unit polyion complex" with siRNA and ASO: a novel DDS alternative to LNP2019
- Author(s)
  T. Yoshida, M. Masai, H. Taniguchi, Y. Kondo, N. Nishiyama, K. Miyata, S. Akinaga, K. Kataoka
- Organizer
  15th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] Intratracheal administered micellar assembly of thermoresponsive polymer-antisense oligonucleotide conjugates for enhanced gene knockdown in lung cancer2019
- Author(s)
  B. S. Kim, S. Ogura, K. Miyata
- Organizer
  2019 Fall Meeting of The Korean Society for Biomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18115
[Presentation] siRNAsome: A self-assembled vesicular architecture formed from siRNAs and PEGylated block catiomers2019
- Author(s)
  B. S. Kim, S. Chuanoi, Y. Anraku, K. Miyata, A. Kishimura, K. Kataoka
- Organizer
  6th International Conference on Multifunctional, Hybrid and Nanomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] 核酸医薬とカチオン性ブロック共重合体の精密設計に基づくナノ構造体の形成挙動制御2019
- Author(s)
  茶谷洋行, 林光太朗, 内藤瑞, キムヒョンジン, 福島重人, 片岡一則, 宮田完二郎
- Organizer
  第28回インテリジェント・ナノ材料シンポジウム
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] siRNAを膜成分として含有するベシクル型ポリイオンコンプレックス(siRNAsome)の構築とsiRNAデリバリーへの展開2018
- Author(s)
  宮田完二郎, キムボブス, チュアノイサヤン, 須磨知也, 安楽泰孝, 内藤瑞, キムヒョンジン, 岸村顕広, 片岡一則
- Organizer
  第40回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-18K19900
[Presentation] Smart oligonucleotide delivery by polymer nanotechnology2018
- Author(s)
  K. Miyata
- Organizer
  The 35th International Conference of Photopolymer Science and Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] 核酸医薬デリバリーのための高分子材料設計2018
- Author(s)
  宮田完二郎
- Organizer
  第13回理研「デジタル×バイオものづくり」シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] 血液脳関門を効率的に通過する脳へのドラッグデリバリーシステムの開発2018
- Author(s)
  桑原宏哉,安楽泰孝,福里優,石井武彦,新田佳子,松本有,藤加珠子,宮田完二郎,内田智士,仁科一隆,長田健介,位高啓史,水澤英洋,片岡一則,横田隆徳
- Organizer
  第36回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] Vesicular self-assemblies from siRNAs and PEGylated block catiomers (siRNAsomes): Their structural, physicochemical, and biological characteristics2018
- Author(s)
  B. S. Kim, K. Miyata, A. Kishimura, K. Kataoka
- Organizer
  The 12th SPSJ International Polymer Conference (IPC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18115
[Presentation] Ultra-small polymeric nanocarriers for cancer-targeted oligonucleotide delivery2018
- Author(s)
  K. Miyata, S. Watanabe, K. Hayashi, K. Toh, H. J. Kim, K. Kataoka
- Organizer
  The 12th SPSJ International Polymer Conference (IPC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] Vesicular self-assemblies from siRNAs and PEGylated block catiomers (siRNAsomes): Their structural, physicochemical, and biological characteristics2018
- Author(s)
  B. S. Kim, K. Miyata, A. Kishimura, K. Kataoka
- Organizer
  The 12th SPSJ International Polymer Conference (IPC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19900
[Presentation] Vesicular self-assemblies from siRNAs and PEGylated block catiomers (siRNAsomes): Their structural, physicochemical, and biological characteristics2018
- Author(s)
  B. S. Kim, K. Miyata, A. Kishimura, K. Kataoka
- Organizer
  The 12th SPSJ International Polymer Conference (IPC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] siRNAを膜成分として含有するベシクル型ポリイオンコンプレックス(siRNAsome)の構築とsiRNAデリバリーへの展開2018
- Author(s)
  宮田完二郎, キムボブス, チュアノイサヤン, 須磨知也, 安楽泰孝, 内藤瑞, キムヒョンジン, 岸村顕広, 片岡一則
- Organizer
  第40回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] siRNAを膜成分として含有するベシクル型ポリイオンコンプレックス(siRNAsome)の構築とsiRNAデリバリーへの展開2018
- Author(s)
  宮田完二郎, キムボブス, チュアノイサヤン, 須磨知也, 安楽泰孝, 内藤瑞, キムヒョンジン, 岸村顕広, 片岡一則
- Organizer
  第40回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-18F18115
[Presentation] 核酸医薬デリバリーのための高分子材料設計2018
- Author(s)
  宮田完二郎
- Organizer
  第13回理研「デジタル×バイオものづくり」シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] リガンド搭載有機無機ハイブリッドナノキャリアによるがんへのsiRNAデリバリー2018
- Author(s)
  宮田完二郎, 易宇, 内藤瑞, キムヒョンジン, 片岡一則
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] 核酸医薬のドラッグデリバリーシステム2017
- Author(s)
  宮田完二郎
- Organizer
  第36回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] Polymer-based oligonucleotide delivery ~challenges and solutions~2017
- Author(s)
  K. Miyata
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki, Japan
- Year and Date
  2017-02-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 高分子材料を基盤とする核酸医薬デリバリー2017
- Author(s)
  宮田完二郎
- Organizer
  CBI学会第384回研究講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] Polymer-based oligonucleotide delivery : challenges and solutions2017
- Author(s)
  K. Miyata
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall (Kanagawa, Japan)
- Year and Date
  2017-02-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Polymer-based oligonucleotide delivery ~challenges and solutions~2017
- Author(s)
  Kanjiro Miyata
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki, Japan
- Year and Date
  2017-02-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] 高分子材料を基盤とする核酸医薬デリバリー2017
- Author(s)
  宮田完二郎
- Organizer
  CBI学会第384回研究講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] Precise construction of gold-nanoparticle architecture with monodispersed polyion complex for siRNA delivery2017
- Author(s)
  H. J. Kim, Y. Yi, K. Miyata, K. Kataoka
- Organizer
  2017 MRS Fall Meeting & Exhibit
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] 1分子核酸封入ポリイオンコンプレックスの調製と核酸デリバリーへの展開2017
- Author(s)
  宮田完二郎, 渡邉秀美代, 藤加珠子, 林光太朗, 内藤瑞, キムヒョンジン, 片岡一則
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] 核酸医薬のドラッグデリバリーシステム2017
- Author(s)
  宮田完二郎
- Organizer
  第36回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] Size-controlled construction of gold nanoparticle-based vehicle with polymeric building blocks for systemic delivery of siRNA2017
- Author(s)
  キムヒョンジン, 易宇, 宮田完二郎, 片岡一則
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] 高分子・無機材料を用いたナノ構造体の創製と核酸医薬デリバリーへの応用2017
- Author(s)
  宮田完二郎
- Organizer
  日本核酸医薬学会第3回年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] 1分子核酸封入ポリイオンコンプレックスの調製と核酸デリバリーへの展開2017
- Author(s)
  宮田完二郎、渡邉秀美代、藤加珠子、林光太朗、内藤瑞、H. -J. Kim、片岡一則
- Organizer
  第33回DDS学会学術大会
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 高分子・無機材料を用いたナノ構造体の創製と核酸医薬デリバリーへの応用2017
- Author(s)
  宮田完二郎
- Organizer
  日本核酸医薬学会第3回年会
- Invited
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] Small polymeric nanocarriers for smart oligonucleotide delivery2017
- Author(s)
  K. Miyata
- Organizer
  Beijing Symposium 2017: Polymeric Biomaterials
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] ナノマシンによるがん治療の最前線2017
- Author(s)
  宮田完二郎
- Organizer
  先端ナノデバイス・材料テクノロジー第151委員会
- Place of Presentation
  川崎川崎生命科学・環境研究センター
- Invited
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] ナノマシンによるがん治療研究の最前線2017
- Author(s)
  宮田完二郎
- Organizer
  先端ナノデバイス・材料テクノロジー第151委員会
- Place of Presentation
  川崎川崎生命科学・環境研究センター
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Small polymeric nanocarriers for smart oligonucleotide delivery2017
- Author(s)
  K. Miyata
- Organizer
  Beijing Symposium 2017: Polymeric Biomaterials
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02098
[Presentation] Development of smart polymeric nanocarriers for targeted siRNA delivery2016
- Author(s)
  K. Miyata
- Organizer
  Frontiers2016 -Joint Symposium of the EPFL and the University of Tokyo
- Place of Presentation
  Swiss Federal Institute of Technology (EPFL) (Lausanne, Switzerland)
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] ナノバイオテクノロジーが先導する診断・治療イノベーション2016
- Author(s)
  宮田完二郎
- Organizer
  GRENE開発講座ナノバイオコース
- Place of Presentation
  東京都目黒区東工大蔵前会館
- Year and Date
  2016-01-13
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 高分子ナノテクノロジーを基盤とする核酸医薬デリバリーシステムの開発2016
- Author(s)
  宮田完二郎
- Organizer
  岐阜大学大学院連合創薬医療情報研究科公開講座
- Place of Presentation
  岐阜県岐阜市岐阜大学サテライトキャンパス
- Year and Date
  2016-01-19
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] ブロック共重合体を用いたsiRNA封入ポリイオンコンプレックスの構造制御とデリバリーへの展開2016
- Author(s)
  宮田完二郎、他
- Organizer
  第65回高分子討論会
- Place of Presentation
  横浜神奈川大学横浜キャンパス
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Development of smart polymeric nanocarriers for targeted siRNA delivery2016
- Author(s)
  K. Miyata
- Organizer
  EPFL/UTokyo Joint Symposium 2016, Lausanne
- Place of Presentation
  Lausanne, Switzerland
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] リガンド搭載高分子ナノ粒子を用いた腫瘍組織特異的核酸デリバリー2016
- Author(s)
  宮田完二郎、他
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  静岡グランシップ
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 高分子ナノキャリアを用いた核酸医薬デリバリー2016
- Author(s)
  宮田完二郎
- Organizer
  第1回RNA創薬セミナー
- Place of Presentation
  大阪大阪医科大学
- Invited
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] Ligand-installed polymeric nanocarriers for targeted drug and nucleic acid delivery2016
- Author(s)
  K. Miyata
- Organizer
  Drug Carriers in Medicine & Biology in Gordon Research Conference
- Place of Presentation
  Waterville Valley, USA
- Year and Date
  2016-08-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Smart polymeric nanocarriers for systemic nucleic acid delivery2016
- Author(s)
  K. Miyata
- Organizer
  12th Annual Meeting of the Oligonucleotide Therapeutics Society
- Place of Presentation
  Montreal, Canada
- Year and Date
  2016-09-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] ユニットPIC/金ナノ粒子ハイブリッドナノキャリアによるがん標的siRNAデリバリー2016
- Author(s)
  宮田完二郎、他
- Organizer
  第26回日本MRS年次大会
- Place of Presentation
  横浜横浜市開港記念会館
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 高分子ナノテクノロジーが切り拓く核酸医薬デリバリー2016
- Author(s)
  宮田完二郎
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2016-10-06
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 高分子ナノキャリアを用いた核酸医薬デリバリー2016
- Author(s)
  宮田完二郎
- Organizer
  第1回RNA創薬セミナー
- Place of Presentation
  大阪大阪医科大学
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Development of smart polymeric nanocarriers for targeted siRNA delivery2016
- Author(s)
  Kanjiro Miyata
- Organizer
  EPFL/UTokyo Joint Symposium 2016, Lausanne
- Place of Presentation
  Lausanne, Switzerland
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16355
[Presentation] 高分子ナノテクノロジーを基盤とする核酸医薬デリバリーシステムの開発2016
- Author(s)
  宮田完二郎
- Organizer
  マテリアル工学セミナー
- Place of Presentation
  東京都文京区東京大学
- Year and Date
  2016-01-15
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Most recent pregress in development of polymeric nanocarriers for siRNA delivery2015
- Author(s)
  K. Miyata, K. Kataoka
- Organizer
  Global RNAi Carrier Initiative Symposium
- Place of Presentation
  KIST, International Cooperation Building (Seoul, Korea)
- Year and Date
  2015-05-26
- Description
  【発表確定】
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Development of Polymeric Nanocarriers for Targeted siRNA Delivery2015
- Author(s)
  K. Miyata, et al
- Organizer
  IUPAC-2015
- Place of Presentation
  Busan, Korea
- Year and Date
  2015-08-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 1分子siRNA封入ユニットポリイオンコンプレックスの精密構造設計2015
- Author(s)
  宮田完二郎、他
- Organizer
  第64回高分子討論会
- Place of Presentation
  宮城県仙台市東北大川内キャンパス
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Development of polymeric nanocarriers for small nucleic acid delivery2015
- Author(s)
  K. Miyata, H. -J. Kim, K. Kataoka
- Organizer
  2015 CRS Annual Meeting
- Place of Presentation
  Edinburgh International Conference Centre (EICC) (Edinburgh, UK)
- Year and Date
  2015-07-28
- Description
  【発表確定】
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Development of Polymeric Materials for Systemic siRNA Delivery to Solid Tumor and Brain2015
- Author(s)
  K. Miyata, et al
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Development of polymeric nanocarriers for targeted siRNA delivery2015
- Author(s)
  K. Miyata, H. -J. Kim, N. Nishiyama, K. Kataoka
- Organizer
  IUPAC-2015
- Place of Presentation
  Bexco (Busan, Korea)
- Year and Date
  2015-08-13
- Description
  【発表確定】
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Multifunctional polygon complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer2015
- Author(s)
  K. Miyata, et al
- Organizer
  42nd CRS Annual Meeting & Exposition
- Place of Presentation
  Edinburgh, Scotland
- Year and Date
  2015-07-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 1分子siRNA封入ユニットポリイオンコンプレックスの精密構造設計2015
- Author(s)
  宮田完二郎, 林光太朗, 茶谷洋行, 渡邉秀美代, 藤加珠子, 福島重人, W. Lan, H. -J. Kim, 武元宏泰, 西山伸宏, 長田健介, 片岡一則
- Organizer
  第64回高分子討論会
- Place of Presentation
  東北大学川内キャンパス(宮城県仙台市)
- Year and Date
  2015-09-17
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 高分子ナノテクノロジーを基盤とする核酸医薬デリバリー2015
- Author(s)
  宮田完二郎, 林光太朗, 内藤瑞, H.-J. Kim, 片岡一則
- Organizer
  第1回日本核酸医薬学会大会
- Place of Presentation
  京都テルサ(京都府京都市)
- Year and Date
  2015-12-01
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 高分子ナノテクノロジーを基盤とする核酸医薬デリバリーシステムの開発2015
- Author(s)
  宮田完二郎
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-07-03
- Description
  【発表確定】
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 高分子ナノテクノロジーによる核酸医薬デリバリー2015
- Author(s)
  宮田完二郎, 片岡一則
- Organizer
  BMB2015 第38回日本分子生物学会年会, 第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2015-12-03
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 高分子ナノテクノロジーを基盤とする核酸医薬デリバリーシステムの開発2015
- Author(s)
  宮田完二郎
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  東京都新宿区京王プラザホテル
- Year and Date
  2015-07-03
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 高分子ナノテクノロジーを基盤とする核酸医薬デリバリー2015
- Author(s)
  宮田完二郎、他
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都府京都市京都テルサ
- Year and Date
  2015-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 高分子ナノテクノロジーによる核酸医薬デリバリー2015
- Author(s)
  宮田完二郎、他
- Organizer
  BMB2015
- Place of Presentation
  兵庫県神戸市神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] N置換ポリアスバルタマイド側鎖の化学構造がmRNAポリプレックスの細胞内安定性及び発現持続性に及ぼす影響2015
- Author(s)
  内田寛邦, 位高啓史, 宮田完二郎, 西山伸宏, 片岡一則
- Organizer
  第1回日本核酸医薬学会大会
- Place of Presentation
  京都テルサ(京都府京都市)
- Year and Date
  2015-12-01
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Development of polymeric nano carriers for systemic siRNA delivery to solid tumors2014
- Author(s)
  Kanjiro Miyata , et al.
- Organizer
  Global RNAi Carrier Initiative Symposium
- Place of Presentation
  ソウル、韓国
- Year and Date
  2014-05-27
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 薬剤・核酸医薬をがんへ送り届ける高分子ナノキャリア2014
- Author(s)
  宮田完二郎
- Organizer
  第25回健康医療開発機構ネットワークセミナー
- Place of Presentation
  東京大学医科学研究所
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 核酸デリバリーのための高分子ナノキャリア設計2014
- Author(s)
  宮田完二郎
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶慮義塾大学(東京都港区)
- Year and Date
  2014-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Development of functional polyplex micelles toward systemic gene therapy2014
- Author(s)
  K. Osada, Q. Chen, T. Tockary, A. Dirisala, K. Miyata, K. Kataoka
- Organizer
  Frontiers of Polymer Colloids : From Synthesis to Macro-Scale and Nano-Scale Applications(FPCOL'14)
- Place of Presentation
  A cademy of Sciences of the Czech Republic(Praha, Czech Republic)
- Year and Date
  2014-07-22
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Development of small polymeric nanocarriers for systemic siRNA delivery2014
- Author(s)
  K. Miyata, K. Kataoka
- Organizer
  The 2014 Fall Meeting, The Polymer Society of Korea
- Place of Presentation
  International Convention Center Jeju(Jeju, Korea)
- Year and Date
  2014-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] リガンド搭載高分子ミセル型ナノキャリアを用いた組織特異的核酸デリバリー2014
- Author(s)
  宮田完二郎, 安楽泰孝, 横田隆徳, 片岡一則
- Organizer
  第33回日本認知症学会学術会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Development of nanobiomaterials for tumor-targeted delivery of small nucleic acids2014
- Author(s)
  宮田完二郎
- Organizer
  FIRST合同国際シンポジウム
- Place of Presentation
  札幌パークホテル
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Enhanced nucleic acids delivery by fine-tuning repeated aminoethylene structures in polyaspartamide side chain2013
- Author(s)
  K. Miyata, H. Uchida, N. Nishiyama, K. Kataoka
- Organizer
  The 4th Asian Symposium on Advanced Materials - Chemistry, Physics & Biomedicine of Functional and Novel Materials
- Place of Presentation
  National Taiwan University of Science and Technology (Taipei, Taiwan)
- Year and Date
  2013-10-23
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Development of polymeric nanocarriers for enhanced siRNA delivery toward cancer therapy2013
- Author(s)
  Kanjiro Miyata, R. J. Christie, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Design of polymeric nanomaterials for enhanced small RNA delivery2013
- Author(s)
  K. Miyata, Y. Maeda, K. Hayashi, H. Takemoto, N. Nishiyama, K. Kataoka
- Organizer
  The 15th Asian Chemical Congress
- Place of Presentation
  Resorts World Sentosa (Sentosa Gateway. Singapore)
- Year and Date
  2013-08-23
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Targeted Nano-Devices for Cancer Treatment with siRNA2013
- Author(s)
  R. J. Christie, K. Miyata, S. Fukushima, Y. Oe, H. Nishida, N. Nishiyama, (K. Kataoka)
- Organizer
  Nanobio FIRST International Symposium between Sweden and Japan Achieving medical innovation by nanobio Bench to Bedside, Bedside to Bench
- Place of Presentation
  Ito Hall, Ito International Research Center, The University of Tokyo, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] siRNA１分子を封入する微小核酸キャリアの開発2013
- Author(s)
  宮田完二郎
- Organizer
  第6回ナノバイオ若手ネットワーキングシンポジウム
- Place of Presentation
  富山県民会館
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Design of polymeric nanomaterials for enhanced small RNA delivery2013
- Author(s)
  Kanjiro Miyata, Kazunori Kataoka
- Organizer
  15th Asian Chemical Congress 2013
- Place of Presentation
  Resorts World Sentosa
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] siRNA-conjugated charge-conversional polymer as a smart material for siRNA delivery2013
- Author(s)
  H. Takemoto, K. Miyata
- Organizer
  16th International Symposium on Recent Advances in Drug Delivery Systems
- Place of Presentation
  シェラトンソルトレイクシティ(ユタ, 米国)
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] 環状RGDペプチドリガンドを装着した高分子ミセル型siRNAキャリアの開発とがん治療への展開2013
- Author(s)
  宮田完二郎
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Design of REGylate poIyion complexes incorporating single siRNA molecule "Effect of chain lengths of PEG-polycation block copolymers on the complex structure and properties"2013
- Author(s)
  K. Osada, H. Chaya, S. Watanabe, H. Takemoto, N. Nishiyama, K. Miyata, K. Kataoka
- Organizer
  21st International Conference on Analytical Ultracentrifugation, Hydrodynamics, Thermodynamics and Complementary Methods (AUC2013)
- Place of Presentation
  Hotel New Akao (Atami, Shizuoka, Japan)
- Year and Date
  2013-09-28
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Effect of block copolymer structure on stability of single siRNA-based polyion complexes2013
- Author(s)
  K. Hayashi, H. Chaya, K. Miyata, S. Watanabe, T. Ishii, S. Fukushima, K. Osada, N. Nishiyama, (K. Kataoka)
- Organizer
  2nd International Conference on Biomaterials Science in Tsukuba ICBS2013
- Place of Presentation
  Tsukuba International Congress Center (EPOCHAL Tsukuba), Tsukuba
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] siRNA１分子を封入する微小核酸キャリアの開発2013
- Author(s)
  宮田完二郎
- Organizer
  第13回次世代医工学研究会
- Place of Presentation
  みのお山荘
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] siRNA-conjugated charge-conversional polymer as a smart material for siRNA delivery2013
- Author(s)
  Hiroyasu Takemoto, Kanjiro Miyata, et al
- Organizer
  16th International Symposium on Recent Advances in Drug Delivery Systems
- Place of Presentation
  シェラトンソルトレイクシティ、ユタ州、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] 高分子ナノ材料を基盤とする核酸医薬デリバリーシステムの開発2013
- Author(s)
  宮田完二郎
- Organizer
  平成25年度厚生労働科学研究費補助金創薬基盤推進研究事業第16回ヒューマンサイエンス総合研究ワークショップ「ナノバイオテクノロジーはどこまで医療に貢献できるか ―現状と展望―」
- Place of Presentation
  御茶ノ水ソラシティ(東京都千代田区)
- Year and Date
  2013-12-25
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] ブロック共重合体の精密設計に基づくsiRNAナノアーキテクチャ形成の量子的制御2013
- Author(s)
  茶谷洋行、渡邉秀美代、武本宏泰、福島重人、宮田完二郎、長田健介、西山伸宏、(片岡一則)
- Organizer
  第22回インテリジェント材料フォーラムシステムシンポジウム
- Place of Presentation
  東京女子医科大学　先端生命医科学研究所、東京
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] Effect of Cholesterol-siRNA on the Stability and Activity of Targeted Polyplex Micelles2013
- Author(s)
  R. J. Christie, Y. Oe, S. Lowe, K. Toh, K. Miyata, S. Fukushima, (K. Kataoka)
- Organizer
  16th International Symposium on RECENT ADVANCES IN DRUG DELIVERY SYSTEMS
- Place of Presentation
  Sheraton Hotel, Salt Lake City, Utah, USA,
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] siRNA1分子封入ポリイオンコンプレックスの構築とsiRNAデリバリーへの展開2013
- Author(s)
  宮田完二郎、茶谷洋行、渡邉秀美代、林光太朗、他
- Organizer
  第35回日本バイオマテリアル学会大会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Enhanced nucleic acids delivery by fine-tuning repeated aminoethylene structures in polyaspartamide side chain2013
- Author(s)
  Kanjiro Miyata, Kazunori Kataoka
- Organizer
  The 4th Asian Symposium on Advanced Materials
- Place of Presentation
  台湾科技大学
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 高分子ナノ材料を基盤とする核酸医薬デリバリーシステムの開発2013
- Author(s)
  宮田完二郎
- Organizer
  第16回ヒューマンサイエンス総合研究ワークショップ
- Place of Presentation
  ソラシティカンファレンスセンター
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Enhanced Blood Circulation Properties of siRNA Nanocarriers by Fine-tuning of PEG-block-Poly(L-lysine)2012
- Author(s)
  S. Watanabe, H. Chaya, K. Miyata, T. Nomoto, S. Fukushima, H. Takemoto, K. Toh, L. Xueying, Y. Matsumoto, K. Osada, N. Nishiyama, (K.Kataoka)
- Organizer
  Kyoto Cell-Material Integration 2012
- Place of Presentation
  Shiran-Kaikan, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] siRNAデリバリー用カチオン性ポリアミノ酸設計2012
- Author(s)
  宮田完二郎
- Organizer
  第61回高分子年次大会
- Place of Presentation
  パシィコ横浜(神奈川県)
- Year and Date
  2012-05-29
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Smart multilayered polymer/silica assemblies for siRNA delivery2012
- Author(s)
  K. Miyata
- Organizer
  NanoBio Seattle
- Place of Presentation
  ベルハーバーインターナショナルコンベンションセンター(ワシントン州、米国)
- Year and Date
  2012-07-24
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Design of functional polymeric nanomaterials for nucleic acid delivery2012
- Author(s)
  K. Miyata
- Organizer
  Oligonucleotide Delivery
- Place of Presentation
  ヘルンシュタイン城(ヘルンシュタイン, オーストリア)
- Year and Date
  2012-10-09
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Enhanced siRNA-polymer click conjugation after gradual freeze-thawing2012
- Author(s)
  Hiroyasu Takemoto, Kanjiro Miyata, et al
- Organizer
  The 9th SPSJ International Polymer Conference (IPC2012)
- Place of Presentation
  神戸国際会議場、兵庫県、日本
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Fine-tuning of polycationic nanomaterials for enhanced nucleic acid delivery2012
- Author(s)
  K. Miyata
- Organizer
  6th Annual Symposium on Nanobiotechnology Kyoto Cell-Material Integration
- Place of Presentation
  京都大学芝蘭会館(京都府)
- Year and Date
  2012-11-07
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Enhanced siRNA-polymer click conjugation after gradual freeze-thawing2012
- Author(s)
  K. Miyata, T. Ishii, N. Nishiyama, (K. Kataoka)
- Organizer
  SPSJ International Polymer Conference
- Place of Presentation
  Kobe Convention center, Hyogo, Japan
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] Smart multilayered polymer/silica assemblies for enhanced siRNA delivery2012
- Author(s)
  K. Miyata
- Organizer
  IUMRS-ICEM2012
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2012-09-26
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Design of functional polymeric nanomaterials for nucleic acid delivery2012
- Author(s)
  Kanjiro Miyata, et al
- Organizer
  Oligonucleotide Delivery: Biology, Engineering and Development
- Place of Presentation
  ヘルンシュタイン城、オーストリア
- Invited
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] siRNA-grafted Polymer for Efficient siRNA Delivery System2012
- Author(s)
  H.Takemoto, K.Miyata, et al
- Organizer
  243rd American Chemical Society National Meeting & Exposition
- Place of Presentation
  Manchester Grand Hyatt(米国カリフォルニア州)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] "Design of PEGylated polyion complexes featuring single siRNA molecule ～Effect of chain lengths of PEG-b-polycations on the complex structure and properties～"2012
- Author(s)
  H. Chaya, S. Watanabe, H. Takemoto, S. Fukushima, K. Miyata, K. Osada, N. Nishiyama, (K. Kataoaka)
- Organizer
  SPSJ International Polymer Conference
- Place of Presentation
  Kobe Convention center, Hyogo, Japan
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] Development of cationic poly(amino acid)s for preparation of polyion complexes with nucleic acids for efficient gene and siRNA delivery2012
- Author(s)
  K. Miyata
- Organizer
  ACS Spring 2012 National Meeting & Exposition
- Place of Presentation
  サンディエゴコンベンションセンター(カリフォルニア州、米国)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] 1分子siRNA封入ポリイオンコンプレックスの構造機能評価2012
- Author(s)
  茶谷洋行、渡邉秀美代、武元宏泰、福島重人、宮田完二郎、長田健介、西山伸宏、(片岡一則)
- Organizer
  第61回高分子討論会
- Place of Presentation
  名古屋工業大学、愛知
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] Enhanced siRNA-polymer click conjugation after gradual freeze-thawing2012
- Author(s)
  H. Takemoto, K. Miyata
- Organizer
  The 9th SPSJ International Polymer Conference (IPC2012)
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] 微小な化学構造の違いに基づいて低毒性/高効率核酸送達を実現する高分子ナノ材料設計2012
- Author(s)
  宮田完二郎
- Organizer
  2012年度日本バイオマテリアル学会
- Place of Presentation
  仙台国際センター(宮城県)
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] 微小な化学構造の違いに基づいて低毒性/高効率核酸送達を実現する高分子ナノ材料設計2012
- Author(s)
  宮田完二郎
- Organizer
  日本バイオマテリアル学会大会シンポジウム2012
- Place of Presentation
  仙台国際会議場、宮城県、日本
- Invited
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Targeted Polymeric Micelles for siRNA Cancer Therapy Administered by Intravenous Injection2012
- Author(s)
  R. J. Christie, Y. Matsumoto, S. Fukushima, T. Nomoto,K. Miyata, K. Osada, F. Pitella, H. -J. Kim, H. Nishida, N. Nishiyama, (K. Kataoka)
- Organizer
  NanoBio Seattle 2012 (The Fourth International NanoBio Conference)
- Place of Presentation
  Bell Harbor International Convention Center, Seattle, USA
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] 核酸デリバリーを指向したカチオン性ポリアミノ酸構造の精密設計2012
- Author(s)
  宮田完二郎
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2012-07-04
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] ポリカチオン構造の精密設計に基づいたポリイオンコンプレックス封入siRNA分子数の制御2012
- Author(s)
  茶谷洋行、渡邉秀美代、武元宏泰、福島重人、宮田完二郎、長田健介、西山伸宏、(片岡一則)
- Organizer
  第61回高分子学会年次大会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] Self-assembled nanostructures of block copolymers as smart vehicles for gene and siRNA delivery2012
- Author(s)
  K. Miyata
- Organizer
  ISACS9
- Place of Presentation
  アモイ大学(アモイ、中国)
- Year and Date
  2012-09-03
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Novel vesicles containing membrane-embedded siRNA as for nucleic acid therapeutics2012
- Author(s)
  S. Chuanoi, A. Kishimura, K. Miyata, T. Suma, Y. Anraku, (K. Kataoka)
- Organizer
  IUMRS-ICEM2012
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] Self-assembled nanostructures of block copolymers as smart vehicles for gene and siRNA delivery2012
- Author(s)
  K. Miyata, (K. Kataoka)
- Organizer
  Challenges in Nanoscience (ISACS9)
- Place of Presentation
  Xiamen University, China
- Invited
- Data Source
  KAKENHI-PROJECT-23350049
[Presentation] Fine-tuning of polycationic nanomaterials for enhanced nucleic acid delivery2012
- Author(s)
  Kanjiro Miyata, et al
- Organizer
  6th Annual Symposium on Nanobiotechnology Kyoto Cell-Material Integration 2012
- Place of Presentation
  京都大学芝蘭会館、京都府、日本
- Invited
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] siRNAグラフト共重合体を基盤とするPIC型スマートキャリアの構築2011
- Author(s)
  武元宏泰、宮田完二郎, 他
- Organizer
  第60回高分子討論会
- Place of Presentation
  岡山大学津島キャンパス(岡山県)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Design of polymeric nanocarrier for siRNA delivery2011
- Author(s)
  K. Miyata
- Organizer
  France-Japan Workshop-The Nanotech Revolution from Science to Society: A Time for Passion and A Time for Reason
- Place of Presentation
  ENS Cachan(パリ、仏国)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Design of Polymeric Nanocarrier for siRNA Delivery2011
- Author(s)
  K.Miyata, et al
- Organizer
  France-Japan Workshop -The Nanotech Revolution from Science to Society-
- Place of Presentation
  ENS Cahan(仏国パリ)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] シリカ被覆型核酸デリバリーキャリアの開発2011
- Author(s)
  宮田完二郎
- Organizer
  第27回日本DDS学会学術集会
- Place of Presentation
  東大本郷キャンパス(東京都)
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] siRNA-grafted polymer for polyion complex(PIC)-based siRNA delivery2011
- Author(s)
  H.Takemoto, K.Miyata, et al
- Organizer
  ICBS2011
- Place of Presentation
  つくば国際会議場(茨城県つくば市)
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] ポリイオンコンプレックス型核酸デリバリーシステム構築に向けたカチオン性ポリアミノ酸構造の検討2011
- Author(s)
  宮田完二郎
- Organizer
  第60回高分子討論会
- Place of Presentation
  岡山大学津島キャンパス(岡山県)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] 安全かつ高効率な核酸デリバリーに向けたカチオン性ポリアミノ酸設計2011
- Author(s)
  宮田完二郎
- Organizer
  第21回日本MRS学術シンポジウム
- Place of Presentation
  横浜情報文化センター(神奈川県)
- Year and Date
  2011-12-20
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Efficient siRNA Delivery Using siRNA-grafted Polymer-based Polyion Complexes2011
- Author(s)
  H.Takemoto, K.Miyata, et al
- Organizer
  38th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Gaylord National Hotel (米国メリーランド州)
- Year and Date
  2011-08-01
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] siRNA・ポリアスパラギン酸グラフト共重合体を基盤とするPIC型siRNAデリバリー2010
- Author(s)
  武元宏泰、宮田完二郎, 他
- Organizer
  第59回高分子討論会
- Place of Presentation
  北海道大学高等教育機能開発総合センター(北海道札幌市)
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] Development of advanced polymer-based nanodevices for siRNA delivery2010
- Author(s)
  K.Miyata, et al
- Organizer
  240th ACS National Meeting
- Place of Presentation
  ボストンコンベンションセンター(米国マサチューセッツ州)
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] 高分子を基盤とする遺伝子キャリアのシリカコーティングとその機能評価2010
- Author(s)
  宮田完二郎
- Organizer
  第26回日本DDS学会学術集会
- Place of Presentation
  大阪国際交流センター(大阪府)
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] 有機無機ハイブリッド型核酸デリバリーキャリアの開発2010
- Author(s)
  宮田完二郎
- Organizer
  第19回ポリマー材料フォーラム
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] 低毒性かつ高効率な遺伝子導入を可能とする高分子キャリアシステムの設計.2010
- Author(s)
  宮田完二郎
- Organizer
  第59回高分子年次大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22700489
[Presentation] 側鎖にエチレンジアミンユニットを有するカチオン性ポリアスパルタミド誘導体から形成される非ウィルス性遺伝子キャリアの機能評価2008
- Author(s)
  宮田完二郎、et.al.
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2008
- Author(s)
  宮田完二郎, et al
- Organizer
  第2回バイオ・ナノテクフォーラムシンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-03-01
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation] カチオン性ポリアスパラギン誘導体を用いた非ウィルス性遺伝子キャリアシステムの構築2008
- Author(s)
  宮田完二郎、大庭誠、石井武彦、山崎裕一、西山伸宏、片岡一則
- Organizer
  第7回多元研研究発表会
- Place of Presentation
  東北大学片平さくらホール
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2008
- Author(s)
  K. Miyata, et al
- Organizer
  分子情報生命化学国際シンポジウムプログラム
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation] カチオン性ポリアスパラギン誘導体を用いた非ウィルス性核酸デリバリーシステムの構築2008
- Author(s)
  宮田完二郎、et.al.
- Organizer
  第57回高分子学会年次大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2008
- Author(s)
  宮田完二郎, et al
- Organizer
  遺伝子・デリバリー研究会
- Place of Presentation
  大阪
- Year and Date
  2008-05-09
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2008
- Author(s)
  K. Miyata, et al
- Organizer
  35th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  USA(New York)
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation] カチオン性ポリアスパラギン誘導体を用いた高分子ミセル型遺伝子デリバリーシステムの構築と遺伝子導入メカニズムの解明2008
- Author(s)
  宮田完二郎、大庭誠、石井武彦、西山伸宏、片岡一則
- Organizer
  バイオ・ナノテクフォーラム
- Place of Presentation
  化学会館
- Year and Date
  2008-03-04
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2008
- Author(s)
  宮田完二郎, et al
- Organizer
  第37回医用高分子シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2008
- Author(s)
  宮田完二郎, et al
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation] Triblock copolmer micelles with biocompatible, endosomal escaping, DNA-condensing functions for systemic gene delivery2008
- Author(s)
  K. Miyata, et.al.
- Organizer
  The 35th annual meeting and exposition of the controlled release society
- Place of Presentation
  New York, USA
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation] Triblock copolmer micelles bearing biocompatible, endosomal escaping, DNA-condensing abilities for systemic gene delivery2008
- Author(s)
  K. Miyata, et.al.
- Organizer
  NanoBio-Seoul 2008
- Place of Presentation
  Seoul, Korea
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2008
- Author(s)
  K. Miyata, et al
- Organizer
  NanoBIo Seoul 2008
- Place of Presentation
  韓国(ソウル)
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2008
- Author(s)
  宮田完二郎, et al
- Organizer
  第57回高分子年次大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation] 低毒性かつ高遺伝子導入効率を示す非ウィルスキャリア用カチオン構造の探索2007
- Author(s)
  宮田完二郎、大庭誠、福島重人、山崎裕一、西山伸宏、片岡一則
- Organizer
  遺伝子・デリバリー研究会第6回シンポジウム
- Place of Presentation
  東大鉄門記念講堂
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2007
- Author(s)
  宮田完二郎, et al
- Organizer
  遺伝子・デリバリー研究会
- Place of Presentation
  東京
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2007
- Author(s)
  K. Miyata, et al
- Organizer
  CNSI/UCLA-CNBI/UT Symposium
- Place of Presentation
  USA(ロサンゼルス)
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2007
- Author(s)
  宮田完二郎, et al
- Organizer
  第56回高分子討論会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation] 低毒性かつ高効率に遺伝子を導入するポリアスパラギン誘導体PAsp(DET)の遺伝子導入メカニズム解明2007
- Author(s)
  宮田完二郎、大庭誠、浅野俊策、福島重人、山崎裕一、西山伸宏、片岡一則
- Organizer
  第56回高分子年次大会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation] アミノリシス反応を介して合成されたカチオン性ポリアスパラギンの遺伝子導入機能2007
- Author(s)
  宮田完二郎、大庭誠、石井武彦、山崎裕一、西山伸宏、片岡一則
- Organizer
  第56回高分子討論会
- Place of Presentation
  名古屋工業大学
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation]2007
- Author(s)
  宮田完二郎, et al
- Organizer
  第56回高分子年次大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation] Preparation and Characterization of a Series of Cationic Polyasparagine Derivatives as a Gene Carrier2007
- Author(s)
  K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
- Organizer
  Symposium on NanoBiotechnology
- Place of Presentation
  CNSI auditorium, UCLA
- Data Source
  KAKENHI-PROJECT-19750088
[Presentation] リガンド搭載高分子ミセル型ナノキャリアを用いた組織特異的核酸デリバリー
- Author(s)
  宮田完二郎、他
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-29 – 2014-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-14F04352
[Presentation] Development of polymeric nano materials for systemic siRNA delivery to solid tumors
- Author(s)
  Kanjiro Miyata, et al.
- Organizer
  Frontiers of Polymer Colloids
- Place of Presentation
  プラハ、チェコ
- Year and Date
  2014-07-20 – 2014-07-24
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Development of small polymeric nano carriers for systemic siRNA delivery to solid tumors
- Author(s)
  Kanjiro Miyata, et al.
- Organizer
  2014 International Conference of the Korean Society of Pharmaceutical Sciences and Technology
- Place of Presentation
  ソウル、韓国
- Year and Date
  2014-11-27 – 2014-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] 核酸デリバリーのための高分子ナノキャリア設計
- Author(s)
  宮田完二郎
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-30 – 2014-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] Development of small polymeric nano carriers for systemic siRNA delivery to solid tumors
- Author(s)
  Kanjiro Miyata, et al
- Organizer
  2014 International Conference of the Korean Society of Pharmaceutical Sciences and Technology
- Place of Presentation
  ソウル、韓国
- Year and Date
  2014-11-27 – 2014-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-14F04352
[Presentation] リガンド搭載高分子ミセル型ナノキャリアを用いた組織特異的核酸デリバリー
- Author(s)
  宮田完二郎、他
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-29 – 2014-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-25282141
[Presentation] ナノバイオテクノロジーが先導する診断・治療イノベーション
- Author(s)
  宮田完二郎
- Organizer
  文科省GRENE開発講座ナノバイオコース
- Place of Presentation
  東京
- Year and Date
  2015-02-16 – 2015-02-17
- Invited
- Data Source
  KAKENHI-PROJECT-14F04352
[]

1. KATAOKA Kazunori (00130245)

# of Collaborated Projects: 6 results

# of Collaborated Products: 63 results
2. NISHIYAMA Nobuhiro (10372385)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
3. OSADA Kensuke (10396947)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
4. ISHII Takehiko (80415075)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. ITAKA Keiji (60292926)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. YAMASAKI Yuichi (00322678)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. KISHIMURA Akihiro (70422326)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
8. YOKOTA Takanori (90231688)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. TSUMOTO Kouhei (90271866)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. UCHIDA Satoshi (20710726)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
11. 関直彦 (50345013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 藤加珠子 (90342732)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. INOGUCHI Satoru

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. ISHIHARA Tomoaki

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. PERCHE FEDERICO

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. ENOKIDA Hideki (80347103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ITESAKO Toshihiko (10642613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ANRAKU Yasutaka (60581585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. MATSUMOTO Yu (80548553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. KANAZAWA Takanori (60434015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 中川昌之 (90164144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 千代丸剛 (60593796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 谷口陽祐 (00452714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 劉学瑩 (30777470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 林光太朗 (00780660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
26. 佐和貞治 (10206013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 中南秀将 (20548515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 野本貴大 (00734732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. 桑原宏哉 (80723486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 内藤瑞 (50755329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 森健 (70335785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 永田哲也 (50362976)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. LAU CHUN YIN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. MIN HYUN SU

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
35. KIM BEOB SOO

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
36. MAITI DEBABRATA

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. INAMOTO Teruo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. Katsushima Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. OBA Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 藤和珠子

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
41. 東治人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. ZHENG Meng

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
43. 青木伊知男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 夏目敦至

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 近藤豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 新城恵子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 武元宏泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
48. 小比賀聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 喜納宏昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 井原健介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. CABRAL Horacio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 宮田哲郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 小山博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Miyata Kanjiro 宮田 完二郎

MIYATA Kanjiro 宮田 完二郎

Research Projects

Research Products

Co-Researchers

ユニットPICを起点とする次世代核酸ナノ医薬の創製と生体内バリア突破に向けた挑戦Principal Investigator

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自発分解性ポリペプチドの精密分子設計と免疫原性回避への挑戦Principal Investigator

Principal Investigator

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Nanostructures with aggregation-induced emission for holistic rheumatoid arthritis treatmentPrincipal Investigator

Principal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

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Development of advanced nanomedicines for brain-targeted oligonucleotide deliveryPrincipal Investigator

Principal Investigator

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シンチレーション粒子内包ナノカプセルの構築と放射線療法への展開Principal Investigator

Principal Investigator

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Development of RNA-embedded membrane nanovesicles and their applications as highly functional bioactive mediatorsPrincipal Investigator

Principal Investigator

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メッセンジャーＲＮＡを安定化する高分子材料の設計と生体内デリバリーヘの挑戦Principal Investigator

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Targeted oligonucleotide delivery by unit polyion complexesPrincipal Investigator

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Principal Investigator

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ＣＲＩＳＰＲ／Ｃａｓ９封入高分子集合体の構築と生体内デリバリーへの挑戦Principal Investigator

Principal Investigator

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Principal Investigator

Miyata Kanjiro 宮田完二郎

MIYATA Kanjiro 宮田完二郎