Kuwahara Hiroya 桑原宏哉

Researcher Number	80723486
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 講師
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 大学院医歯学総合研究科, 講師 2022 – 2024: 東京医科歯科大学, 大学院医歯学総合研究科, 講師
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 52020:Neurology-related
Keywords	Principal Investigator 核酸医薬 / siRNA / プリオン病 / グルコースミセル / ヘテロ核酸 / 血液脳関門 Except Principal Investigator 核酸医薬 / トランスクリプトーム解析 / RFX遺伝子 / RFX / 自閉症スペクトラム障害 / グリオーシス / アンチセンス核酸

siRNAを用いたプリオン病の治療戦略の概念実証基盤研究Principal Investigator
- Principal Investigator
  
  桑原宏哉
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Institute of Science Tokyo
Elucidation of novel pathogenic pathways through comprehensive identification of regulatory genes for the autism transcription factor RFX
- Principal Investigator
  
  中山東城
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tokyo Medical and Dental University
Development of heteroduplex-oligonucleotide-containing glucose micelle as a blood-brain barrier-crossing nucleic acid drugPrincipal Investigator
- Principal Investigator
  
  桑原宏哉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokyo Medical and Dental University
グリオーシス回避を可能とする2本鎖核酸医薬の開発
- Principal Investigator
  
  吉岡耕太郎
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tokyo Medical and Dental University

All 2023 2022

All Journal Article Presentation Book

[Book] 中分子創薬に向けたDDS開発の新展開2022
- Author(s)
  桑原宏哉、横田隆徳
- Total Pages
  7
- Publisher
  シーエムシー出版
- ISBN
  9784781316598
- Data Source
  KAKENHI-PROJECT-23K24042
[Journal Article] 核酸医薬によるN-of-1+創薬の動向2023
- Author(s)
  中山東城，桑原宏哉，横田隆徳
- Journal Title
  
  バイオサイエンスとインダストリー（B&I）
  
  Volume: 81 Pages: 166-169
- Data Source
  KAKENHI-PROJECT-23K24042
[Journal Article] 神経疾患に対する核酸医薬：超希少疾病の核酸医薬による個別化医療2023
- Author(s)
  中山東城，桑原宏哉，横田隆徳
- Journal Title
  
  脳神経内科
  
  Volume: 98 Pages: 881-885
- Data Source
  KAKENHI-PROJECT-23K24042
[Journal Article] 希少疾患に対する核酸医薬によるN-of-1+創薬の課題と展望2023
- Author(s)
  中山東城、桑原宏哉、横田隆徳
- Journal Title
  
  Pharmaceutical and Medical Device Regulatory Science
  
  Volume: 54 Issue: 1 Pages: 51-54
- DOI
  10.51018/pmdrs.54.1_51
- ISSN
  1884-6076, 2436-6226
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-23K24042
[Presentation] Establishing a Model for N-of-1 Oligonucleotide Therapeutics: Prospect and Challenge in Japan2023
- Author(s)
  Tojo Nakayama, Hiroya Kuwahara, Tetsuya Nagata, Takanori Yokota
- Organizer
  日本核酸医薬学会第8回年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24042
[Presentation] 核酸医薬品におけるsiRNAの位置づけとDDSの進歩2023
- Author(s)
  桑原宏哉
- Organizer
  第64回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24042
[Presentation] DNA and RNA heteroduplex oligonucleotide targeting central nervous system disorders2023
- Author(s)
  Hiroya Kuwahara
- Organizer
  Asian Pacific Prion Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24042
[Presentation] Angubindin-1 opens the blood-brain barrier in vivo for delivery of antisense oligonucleotide to the central nervous system2023
- Author(s)
  Hiroya Kuwahara, Satoshi Zeniya, Tetsuya Nagata, Takanori Yokota
- Organizer
  American Academy of Neurology 75th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24042

1. 吉岡耕太郎 (70780641)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 宮田完二郎 (50436523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 原倫太朗 (70709766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 中山東城 (40613302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山田剛史 (80633263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kuwahara Hiroya 桑原 宏哉

Research Projects

Research Products

Co-Researchers

siRNAを用いたプリオン病の治療戦略の概念実証基盤研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of novel pathogenic pathways through comprehensive identification of regulatory genes for the autism transcription factor RFX

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of heteroduplex-oligonucleotide-containing glucose micelle as a blood-brain barrier-crossing nucleic acid drugPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

グリオーシス回避を可能とする2本鎖核酸医薬の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 中分子創薬に向けたDDS開発の新展開2022

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] 核酸医薬によるN-of-1+創薬の動向2023

Author(s)

Journal Title

Data Source

[Journal Article] 神経疾患に対する核酸医薬：超希少疾病の核酸医薬による個別化医療2023

Author(s)

Journal Title

Data Source

[Journal Article] 希少疾患に対する核酸医薬によるN-of-1+創薬の課題と展望2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Presentation] Establishing a Model for N-of-1 Oligonucleotide Therapeutics: Prospect and Challenge in Japan2023

Author(s)

Organizer

Data Source

[Presentation] 核酸医薬品におけるsiRNAの位置づけとDDSの進歩2023

Author(s)

Organizer

Data Source

[Presentation] DNA and RNA heteroduplex oligonucleotide targeting central nervous system disorders2023

Author(s)

Organizer

Data Source

[Presentation] Angubindin-1 opens the blood-brain barrier in vivo for delivery of antisense oligonucleotide to the central nervous system2023

Author(s)

Organizer

Data Source

Kuwahara Hiroya 桑原宏哉