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Yamasaki Manabu  山崎 学

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… Alternative Names

山崎 学  ヤマサキ マナブ

YAMASAKI Manabu  山崎 学

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Researcher Number 50442570
Other IDs
Affiliation (Current) 2022: 公益財団法人微生物化学研究会, 微生物化学研究所, 研究員
Affiliation (based on the past Project Information) *help 2022: 公益財団法人微生物化学研究会, 微生物化学研究所, 研究員
2015 – 2017: 公益財団法人微生物化学研究会, 微生物化学研究所, 研究員
2013: (公財)微生物化学研究会, 微生物化学研究所, 研究員
2012 – 2013: 公益財団法人微生物化学研究会, 微生物化学研究所, 研究員
Review Section/Research Field
Principal Investigator
General medical chemistry / Virology / Basic Section 47050:Environmental and natural pharmaceutical resources-related
Except Principal Investigator
Virology
Keywords
Principal Investigator
抗ウイルス薬 / インフルエンザウイルス / RNAポリメラーゼ / エンドヌクレアーゼ / キャップ構造 / 質量分析フットプリント法 / 構造変化 / B型肝炎ウイルス / ゲノム複製 / 創薬標的分子 … More / ケミカルバイオロジー / SARS-CoV-2 / メインプロテアーゼ / パパイン様プロテアーゼ / 微生物由来天然物 … More
Except Principal Investigator
ポリオウイルス / 病原性 / 血液脳関門 / 特異的体内伝播 / 宿主因子 Less
  • Research Projects

    (4 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (10 People)
  •  Drug discovery through identification of microbial products against SARS-CoV-2 proteasesPrincipal Investigator

    • Principal Investigator
      山崎 学
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Microbial Chemistry Research Foundation
  •  Search for new potential drug targets for Hepatitis B virus genome replication based on chemical biologyPrincipal Investigator

    • Principal Investigator
      YAMASAKI Manabu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Microbial Chemistry Research Foundation
  •  Identification of a novel inhibitor of influenza virus polymerase based on inhibition of conformational change required for cap-dependent endonuclease activityPrincipal Investigator

    • Principal Investigator
      YAMASAKI Manabu
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Microbial Chemistry Research Foundation
  •  Analysis of poliovirus permeation mechanism through blood brain barier

    • Principal Investigator
      NOMOTO Akio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Microbial Chemistry Research Foundation

All 2017 2014 2013 2012 2011 Other

All Journal Article Presentation

  • [Journal Article] Efficient genome replication of hepatitis B virus using adenovirus vector: a compact pregenomic RNA-expression unit.2017

    • Author(s)
      Suzuki M, Kondo S, Yamasaki M, Matsuda N, Nomoto A, Suzuki T, Saito I, Kanegae Y.
    • Journal Title

      Sci Rep.

      Volume: 7 Pages: 1-11

    • DOI

      10.1038/srep41851

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15J05883, KAKENHI-PROJECT-15K08507
  • [Journal Article] Current landscape and future prospects of antiviral drugs derived from microbial products2017

    • Author(s)
      Takizawa Naoki、Yamasaki Manabu
    • Journal Title

      The Journal of Antibiotics

      Volume: 71 Pages: 45-52

    • DOI

      10.1038/ja.2017.115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08507
  • [Journal Article] The essential role for the RNA triphosphatase Cet1p in nuclear import of the mRNA capping enzyme Cet1p-Ceg1p complex of Saccharomyces cerevisiae2013

    • Author(s)
      Naoki Takizawa, Toshinobu Fujiwara, Manabu Yamasaki, Ayako Saito, Akira Fukao, Akio Nomoto, Kiyobisa Mizumoto
    • Journal Title

      PLoS One

      Volume: 8(10)

    • DOI

      10.1371/journal.pone.0078000

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J02416, KAKENHI-PROJECT-23390113, KAKENHI-PUBLICLY-24115715, KAKENHI-PROJECT-24659139, KAKENHI-PROJECT-25291007, KAKENHI-PROJECT-25670151, KAKENHI-PROJECT-25871077
  • [Presentation] 新規RNA 5'-トリホスファターゼ阻害物質MI481-42F6 A, B, CおよびDに関する研究2014

    • Author(s)
      梅北まや、五十嵐雅之、澤竜一、山崎学、林千草、波多野和樹、藤原俊伸、水本清久、野本明男
    • Organizer
      日本農芸化学会2014年度大会
    • Place of Presentation
      明治大学生田キャンパス(川崎市)
    • Year and Date
      2014-03-30
    • Data Source
      KAKENHI-PROJECT-24659139
  • [Presentation] インフルエンザウイルスRNAポリメラーゼがもつキャップ依存エンドヌクレアーゼ活性を阻害する低分子化合物の探索2013

    • Author(s)
      山崎学、滝沢直己、藤原俊伸、水本清久、野本明男
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2013-11-11
    • Data Source
      KAKENHI-PROJECT-24659139
  • [Presentation] インフルエンザウイルスRNA ポリメラーゼがもつキャップ依存エンドヌクレアーゼ活性を阻害する低分子化合物の探索2013

    • Author(s)
      山崎学, 滝沢直己, 藤原俊伸, 水本清久, 野本明男
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2013-11-11
    • Data Source
      KAKENHI-PROJECT-23390113
  • [Presentation] The essential role for RNA triphosphatase Cet1p in nuclear import of capping enzyme complex in Saccharomyces cervisiae2012

    • Author(s)
      Naoki Takizawa, Toshinobu Fujiwara, Manabu Yamasaki, Kiyohisa Mizumoto, and Akio Nomoto
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2012-12-12
    • Data Source
      KAKENHI-PROJECT-23390113
  • [Presentation] The essential role for RNA triphosphatase Cet1p in transport of capping enzyme in Saccharomyces cerevisiae2012

    • Author(s)
      Naoki Takizawa, Toshinobu Fujiwara, Manabu Yamasaki, Kiyohisa Mizumoto, and Akio Nomoto
    • Organizer
      The 22nd CDB Meeting : RNA Sciences in Cell and Developmental Biology II
    • Place of Presentation
      理研 CDB (神戸市)
    • Year and Date
      2012-06-11
    • Data Source
      KAKENHI-PROJECT-23390113
  • [Presentation] Characterization of a receptor for poliovirus BBB-permeation2011

    • Author(s)
      Coh-ichi Nihei, Manabu Yamasaki, and Akio Nomoto
    • Organizer
      International Union of Microbiological Societies 2011 Congress (IUMS)
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PROJECT-23390113
  • [Presentation] The essential role for RNA triphosphatase Cet1p in transport of capping enzyme in Saccharomyces cerevisiae

    • Author(s)
      Naoki Takizawa, Toshinobu Fujiwara, Manabu Yamasaki, Kiyohisa Mizumoto, Akio Nomoto
    • Organizer
      The 22nd CDB Meeting: RNA Sciences in Cell and Developmental Biology II
    • Place of Presentation
      理研CDB (神戸)
    • Data Source
      KAKENHI-PROJECT-23390113
  • [Presentation] ポリオウイルスの血液脳関門透過機構の解析

    • Author(s)
      水谷 壮利、二瓶 浩一、山崎 学、石坂 彩、野本 明男
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      グランキューブ大阪 (大阪)
    • Data Source
      KAKENHI-PROJECT-23390113
  • [Presentation] インフルエンザウイルスRNAポリメラーゼがもつキャップ依存エンドヌクレアーゼ活性を阻害する低分子化合物の探索

    • Author(s)
      山崎学、滝沢直己、藤原俊伸、水本清久、野本明男
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-24659139
  • [Presentation] 新規RNA5’-トリホスファターゼ阻害物質MI481-42F6 A,B,CおよびDに関する研究

    • Author(s)
      梅北まや、五十嵐雅之、澤竜一、山崎学、林千草、波多野和樹、藤原俊伸、水本清久、野本明男
    • Organizer
      日本農芸化学会2014年度大会
    • Place of Presentation
      明治大学生田キャンパス(川崎市)
    • Data Source
      KAKENHI-PROJECT-24659139
  • 1.  NOMOTO Akio (70112670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 2.  ARAKAWA Masayuki (90398868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  TAKIZAWA Naoki (50448502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  MIZUMOTO Kiyohisa (80092344)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  SAITO Izumu (70158913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  KANEGAE Yumi (80251453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  KONDO Saki (80451871)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  IGARASHI Masayuki (40260137)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SAWA Ryuichi (50235454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  藤原 俊伸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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