OKADA Yoshiaki 岡田欣晃

… Alternative Names

Okada Yoshiaki 岡田欣晃

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Researcher Number	50444500
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院薬学研究科, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 大阪大学, 大学院薬学研究科, 准教授 2020 – 2021: 大阪大学, 薬学研究科, 准教授 2017 – 2018: 大阪大学, 薬学研究科, 准教授 2012 – 2016: 大阪大学, 薬学研究科(研究院), 准教授 2012: 大阪大学, 薬学研究科, 准教授 … More 2011: 大阪大学, 薬学研究科(研究院), 助教 2007 – 2011: Osaka University, 大学院・薬学研究科, 助教 2007 – 2011: 大阪大学, 薬学研究科, 助教 2008: 阪大, 薬学研究科(研究院), 助教 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Pharmaceutical Sciences and related fields / Drug development chemistry Except Principal Investigator Biological pharmacy / Basic Section 90110:Biomedical engineering-related / Medical pharmacy
Keywords	Principal Investigator 血管内皮細胞 / Robo4 / 治療薬 / 炎症 / 敗血症 / 線維芽細胞 / ダイレクトリプログラミング / 重症感染症 / エピジェネティクス / DNAメチル化 … More / Robo4遺伝子 / 遺伝子発現制御 / 罹患後症状 / 血管バリア / 線維症 / 転写因子 / 線維化疾患 / 炎症疾患 / 血管透過性 / 炎症性疾患 / 血管生物学 / DDS / 薬学 / 抗体 / Claudin-5 / 血液脳関門 / シグナル伝達系 / 炎症性サイトカイン / 免疫細胞 / HDAC阻害剤 / スクリーニング系 / 低分子化合物 / インターロイキン6 / 単球 / 人工核酸 / エビジェネティクス / Hprtターゲティング法 / 組織特異性 / 組織特異的遺伝子発現 / 分子生物学 / 転写制御 / トランスジェニックマウス / Roundabout4 / 遺伝子発現調節 … More Except Principal Investigator CAR-T細胞免疫療法 / T細胞免疫療法 / 乳がん / 腫瘍内免疫微小環境 / がん免疫療法 / イムノモジュレーション / 腫瘍微小環境 / 養子免疫療法 / マイクロバブル / 超音波 / GABP / SP1 / 血管内皮細胞 / エピジェネティクス / DNAメチル化 / Robo4遺伝子 / 組織特異的遺伝子発現 / 医療薬剤学 / MRI / SPECT / 抗体 / 腫瘍血管 / 医用・生体画像 / OP9 / Hprt ターゲティング法 / ES細胞 / 巨核球 / 転写因子 / RUNX1 / 分化 / 遺伝子発現制御 / 血小板 Less

血管バリアに着目する新しい視点での重症感染症の病態・後遺症発症機構の解明と制御Principal Investigator
- Principal Investigator
  
  岡田欣晃
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Osaka University
血管を経由する新発想での臓器の脱線維化技術の開発Principal Investigator
- Principal Investigator
  
  岡田欣晃
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University
Development of anti-inflammatory drugs targeting vascular permeabilityPrincipal Investigator
- Principal Investigator
  
  Okada Yoshiaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Osaka University
Development of novel treatment for fibrotic diseases using direct reprogramming technologyPrincipal Investigator
- Principal Investigator
  
  Okada Yoshiaki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University
Development of novel cancer therapy based on promotion of tumor infiltrating lymphocyte by the immunomodulation with ultrasound technology
- Principal Investigator
  
  Suzuki Ryo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Teikyo University
A novel technology for regulating blood brain barrierPrincipal Investigator
- Principal Investigator
  
  Okada Yoshiaki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  Osaka University
Novel anti-sepsis strategy targeting the endothelial cell-specific receptor Robo4Principal Investigator
- Principal Investigator
  
  Okada Yoshiaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
A novel anti-inflammatory strategy by targeting endothelial cell-specific receptor, Robo4Principal Investigator
- Principal Investigator
  
  OKADA Yoshiaki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka University
Regulation mechanisms involved in tissue-specific gene expression
- Principal Investigator
  
  DOI Takefumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
DNA methylation and endothelial cell-specific gene expressionPrincipal Investigator
- Principal Investigator
  
  OKADA Yoshiaki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
Construction of antibody-based molecular imaging techniques to analyze a development of tumor angiogenesis.
- Principal Investigator
  
  MUKAI Yohei
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka University
The mechanism for endothelial cell-specific gene expression through the Robo4 promoter.Principal Investigator
- Principal Investigator
  
  OKADA Yoshiaki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
Transcription factors regulating normal and pathological platelet differentiation
- Principal Investigator
  
  DOI Takefumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
血管内皮細胞に特異的に発現するROBO4の発現制御機構の解析Principal Investigator
- Principal Investigator
  
  岡田欣晃
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University

[Journal Article] Potential Therapeutic Strategies and Drugs That Target Vascular Permeability in Severe Infectious Diseases2024
- Author(s)
  Okada Yoshiaki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 47 Issue: 3 Pages: 549-555
- DOI
  10.1248/bpb.b24-00028
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2024-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03382
[Journal Article] Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models2023
- Author(s)
  Morita M, Yoneda A, Tokunoh N, Masaki T, Shirakura K, Kinoshita M, Hashimoto R, Shigesada N, Takahashi J, Tachibana M, Tanaka S, Obana M, Hino N, Ikawa M, Tsujikawa K, Ono C, Matsuura Y, Kidoya H, Takakura N, Kubota Y, Doi T, Takayama K, Yoshioka Y, Fujio Y, Okada Y.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 3
- DOI
  10.1073/pnas.2213317120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06560, KAKENHI-PROJECT-20H03382
[Journal Article] Runx1 is upregulated by STAT3 and promotes proliferation of neonatal rat cardiomyocytes2023
- Author(s)
  Suzuki Shota、Tanaka Shota、Kametani Yusuke、Umeda Ayaka、Nishinaka Kosuke、Egawa Kaho、Okada Yoshiaki、Obana Masanori、Fujio Yasushi
- Journal Title
  
  Physiological Reports
  
  Volume: 11 Issue: 23
- DOI
  10.14814/phy2.15872
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03382
[Journal Article] Yes‐associated protein activation potentiates glycogen synthase kinase‐3 inhibitor‐induced proliferation of neonatal cardiomyocytes and iPS cell‐derived cardiomyocytes2022
- Author(s)
  Kametani Y, Tanaka S, Wada Y, Suzuki S, Umeda A, Nishinaka K, Okada Y, Maeda M, Miyagawa S, Sawa Y, Obana M, Fujio Y.
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 237 Issue: 5 Pages: 2539-2549
- DOI
  10.1002/jcp.30724
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03382, KAKENHI-PROJECT-20K21575
[Journal Article] Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling2022
- Author(s)
  Tomimatsu M, Matsumoto K, Ashizuka M, Kumagai S, Tanaka S, Nakae T, Yokota K, Kominami S, Kajiura R, Okuzaki D, Motooka D, Shiraishi A, Abe T, Matsuda H, Okada Y, Maeda M, Seno S, Obana M, Fujio Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 16656-16656
- DOI
  10.1038/s41598-022-21202-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03382
[Journal Article] SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression2022
- Author(s)
  Hashimoto Rina、Takahashi Junya、Shirakura Keisuke、Funatsu Risa、Kosugi Kaori、Deguchi Sayaka、Yamamoto Masaki、Tsunoda Yugo、Morita Maaya、Muraoka Kosuke、Tanaka Masato、Kanbara Tomoaki、Tanaka Shota、Tamiya Shigeyuki、Tokunoh Nagisa、Kawai Atsushi、Ikawa Masahito、Ono Chikako、Tachibana Keisuke. et al
- Journal Title
  
  Science Advances
  
  Volume: 8 Issue: 38
- DOI
  10.1126/sciadv.abo6783
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15276, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22KJ1862, KAKENHI-PROJECT-21K20718, KAKENHI-PROJECT-20H03382
[Journal Article] CXCL10 is a novel anti‐angiogenic factor downstream of p53 in cardiomyocytes2022
- Author(s)
  Wahyuni T, Tanaka S, Igarashi R, Miyake Y, Yamamoto A, Mori S, Kametani Y, Tomimatsu M, Suzuki S, Yokota K, Okada Y, Maeda M, Obana M, Fujio Y.
- Journal Title
  
  Physiological Reports
  
  Volume: 10 Issue: 9
- DOI
  10.14814/phy2.15304
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03382
[Journal Article] Upregulation of OASIS/CREB3L1 in podocytes contributes to the disturbance of kidney homeostasis2022
- Author(s)
  Miyake Yoshiaki、Obana Masanori、Yamamoto Ayaha、Noda Shunsuke、Tanaka Koki、Sakai Hibiki、Tatsumoto Narihito、Makino Chihiro、Kanemoto Soshi、Shioi Go、Tanaka Shota、Maeda Makiko、Okada Yoshiaki、Imaizumi Kazunori、Asanuma Katsuhiko、Fujio Yasushi
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 734-734
- DOI
  10.1038/s42003-022-03709-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ2164, KAKENHI-PROJECT-20H03382
[Journal Article] Lipin-1 is a novel substrate of protein phosphatase PGAM52019
- Author(s)
  Okuno Hiroko、Okuzono Haruna、Hayase Ayaka、Kumagai Fumiko、Tanii Shohei、Hino Nobumasa、Okada Yoshiaki、Tachibana Keisuke、Doi Takefumi、Ishimoto Kenji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 509 Issue: 4 Pages: 886-891
- DOI
  10.1016/j.bbrc.2019.01.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19403, KAKENHI-PROJECT-18H03190, KAKENHI-PROJECT-17K19487
[Journal Article] Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires Hes1 to bind diverse DNA sites2019
- Author(s)
  Noguchi Yu-taro、Nakamura Miki、Hino Nobumasa、Nogami Jumpei、Tsuji Sayaka、Sato Takahiko、Zhang Lidan、Tsujikawa Kazutake、Tanaka Toru、Izawa Kohei、Okada Yoshiaki、Doi Takefumi、Kokubo Hiroki、Harada Akihito、Uezumi Akiyoshi、Gessler Manfred、Ohkawa Yasuyuki、Fukada So-ichiro
- Journal Title
  
  Development
  
  Volume: 146 Issue: 4 Pages: 163618-163618
- DOI
  10.1242/dev.163618
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19403, KAKENHI-PUBLICLY-18H04802, KAKENHI-PROJECT-16H03262, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-17K19356, KAKENHI-PROJECT-17K19487, KAKENHI-PROJECT-16K08443
[Journal Article] Endothelial cell-specific gene expression induced by transcription factors and epigenetics2019
- Author(s)
  岡田欣晃
- Journal Title
  
  生化学
  
  Volume: 91 Issue: 1 Pages: 96-100
- DOI
  10.14952/SEIKAGAKU.2019.910096
- NAID
  40021833046
- ISSN
  0037-1017
- Year and Date
  2019-02-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19487
[Journal Article] ETV2-TET1/TET2 Complexes Induce Endothelial Cell-Specific Robo4 Expression via Promoter Demethylation.2018
- Author(s)
  Tanaka Toru、Izawa Kohei、Maniwa Yusuke、Okamura Maki、Okada Atsumasa、Yamaguchi Tomoko、Shirakura Keisuke、Maekawa Naoki、Matsui Hayato、Ishimoto Kenji、Hino Nobumasa、Nakagawa Osamu、Aird William C.、Mizuguchi Hiroyuki、Kawabata Kenji、Doi Takefumi、Okada Yoshiaki
- Journal Title
  
  Sci Rep.
  
  Volume: 8(1) Issue: 1 Pages: 5653-5653
- DOI
  10.1038/s41598-018-23937-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19487, KAKENHI-PROJECT-16K21142
[Journal Article] Pancreatic adenocarcinoma upregulated factor has oncogenic functions in oral squamous cell carcinoma2018
- Author(s)
  Sasahira T, Kurihara M, Nishiguchi Y, Nakashima C, Kirita T, Kuniyasu H.
- Journal Title
  
  Histopathol
  
  Volume: 70 Pages: 539-548
- DOI
  10.1016/j.ejps.2018.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-16K08370, KAKENHI-PROJECT-17K19923, KAKENHI-PROJECT-17K19487, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17J03990
[Journal Article] Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs2018
- Author(s)
  Hashimoto Yosuke、Okada Yoshiaki、Shirakura Keisuke、Tachibana Keisuke、Sawada Makoto、Yagi Kiyohito、Doi Takefumi、Kondoh Masuo
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 368 Issue: 2 Pages: 179-186
- DOI
  10.1124/jpet.118.252361
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-17K19487, KAKENHI-PROJECT-17J03990
[Journal Article] Endothelial Robo4 regulates IL-6 production by endothelial cells and monocytes via a crosstalk mechanism in inflammation2018
- Author(s)
  Shirakura Keisuke、Ishiba Ryosuke、Kashio Taito、Sakai Miki、Fukushima Yu、Yamamoto Nana、Manabe Shiori、Shigesada Naoya、Tanaka Toru、Hino Nobumasa、Aird William C.、Doi Takefumi、Okada Yoshiaki
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 495 Issue: 1 Pages: 801-806
- DOI
  10.1016/j.bbrc.2017.11.067
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19487, KAKENHI-PROJECT-16K21142
[Journal Article] The Robo4-TRAF7 complex suppresses endothelial hyperpermeability in inflammation2018
- Author(s)
  Shirakura Keisuke、Ishiba Ryosuke、Kashio Taito、Funatsu Risa、Tanaka Toru、Fukada So-ichiro、Ishimoto Kenji、Hino Nobumasa、Kondoh Masuo、Ago Yukio、Fujio Yasushi、Yano Kiichiro、Doi Takefumi、Aird William C.、Okada Yoshiaki
- Journal Title
  
  Journal of Cell Science
  
  Volume: 132 Pages: 220228-220228
- DOI
  10.1242/jcs.220228
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19403, KAKENHI-PROJECT-17K19487, KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-18K19545
[Journal Article] Tumor Necrosis Factor α Induces the Expression of the Endothelial Cell-Specific Receptor Roundabout4 through the Nuclear Factor-κB Pathway2017
- Author(s)
  Tanaka T, Maekawa N, Kashio T, Izawa K, Ishiba R, Shirakura K, Ishimoto K, Hino N, Aird WC, Doi T, Okada Y.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 4 Pages: 504-509
- DOI
  10.1248/bpb.b16-00938
- NAID
  130005530067
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293014, KAKENHI-PROJECT-16K21142
[Journal Article] Claudin-5-Binders Enhance Permeation of Solutes across the Blood-Brain Barrier in a Mammalian Model2017
- Author(s)
  Hashimoto Yosuke、Shirakura Keisuke、Okada Yoshiaki、Takeda Hiroyuki、Endo Kohki、Tamura Maki、Watari Akihiro、Sadamura Yoshifusa、Sawasaki Tatsuya、Doi Takefumi、Yagi Kiyohito、Kondoh Masuo
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 363 Issue: 2 Pages: 275-283
- DOI
  10.1124/jpet.117.243014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19487, KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-16K08370, KAKENHI-PROJECT-17J03990
[Journal Article] Angubindin-1, a novel paracellular absorption enhancer acting at the tricellular tight junction.2017
- Author(s)
  Krug SM, Hayaishi T, Iguchi D, Watari A,Takahashi A, Fromm M, Nagahama M, Takeda H, Okada Y,Sawasaki T, Doi T, Yagi K, Kondoh M
- Journal Title
  
  J. Control. Release.
  
  Volume: 260 Pages: 1-11
- DOI
  10.1016/j.jconrel.2017.05.024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08794, KAKENHI-PROJECT-17K19487, KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-16K08370
[Journal Article] Degradation of human Lipin-1 by BTRC E3 ubiquitin ligase2017
- Author(s)
  Ishimoto Kenji、Hayase Ayaka、Kumagai Fumiko、Kawai Megumi、Okuno Hiroko、Hino Nobumasa、Okada Yoshiaki、Kawamura Takeshi、Tanaka Toshiya、Hamakubo Takao、Sakai Juro、Kodama Tatsuhiko、Tachibana Keisuke、Doi Takefumi
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 488 Issue: 1 Pages: 159-164
- DOI
  10.1016/j.bbrc.2017.04.159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19487, KAKENHI-PROJECT-16H06390, KAKENHI-PUBLICLY-16H01382, KAKENHI-PROJECT-15H02896, KAKENHI-PROJECT-16F16725, KAKENHI-PROJECT-16K13042, KAKENHI-PROJECT-16K21142
[Journal Article] Creation of a Claudin-2 Binder and Its Tight Junction?Modulating Activity in a Human Intestinal Model2017
- Author(s)
  Takigawa Mutsumi、Iida Manami、Nagase Shotaro、Suzuki Hidehiko、Watari Akihiro、Tada Minoru、Okada Yoshiaki、Doi Takefumi、Fukasawa Masayoshi、Yagi Kiyohito、Kunisawa Jun、Kondoh Masuo
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 363 Issue: 3 Pages: 444-451
- DOI
  10.1124/jpet.117.242214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19487, KAKENHI-PROJECT-26293111, KAKENHI-PROJECT-16K08370
[Journal Article] Adenovirus vector-based incorporation of a photo-cross-linkable amino acid into proteins in human primary cells and cancerous cell lines.2016
- Author(s)
  Kita A, Hino N, Higashi S, Hirota K, Narumi R, Adachi J, Takafuji K, Ishimoto K, Okada Y, Sakamoto K, Tomonaga T, Takashima S, Mizuguchi H, Doi T.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 36946-36946
- DOI
  10.1038/srep36946
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-26291035, KAKENHI-PROJECT-26293014, KAKENHI-PROJECT-16K21142
[Journal Article] Ubiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase Activity.2016
- Author(s)
  Ishimoto K, Kawamata N, Uchihara Y, Okubo M, Fujimoto R, Gotoh E, Kakinouchi K, Mizohata E, Hino N, Okada Y, Mochizuki Y, Tanaka T, Hamakubo T, Sakai J, Kodama T, Inoue T, Tachibana K, Doi T
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 10 Pages: e0165766-e0165766
- DOI
  10.1371/journal.pone.0165766
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02896, KAKENHI-PROJECT-15H04644, KAKENHI-PROJECT-25282230, KAKENHI-PROJECT-26293014, KAKENHI-PROJECT-16K21142, KAKENHI-PROJECT-16H06390
[Journal Article] Efficacy and safety evaluation of claudin-4-targeted antitumor therapy using a human and mouse cross-reactive monoclonal antibody.2016
- Author(s)
  Hashimoto Y, Kawahigashi Y, Hata T, Li X, Watari A, Tada M, Ishii-Watabe A, Okada Y, Doi T, Fukasawa M, Kuniyasu H, Yagi K, Kondoh M
- Journal Title
  
  Pharmacol Res Perspect
  
  Volume: 4 Issue: 5
- DOI
  10.1002/prp2.266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-26293014, KAKENHI-PROJECT-15J10065
[Journal Article] Generation and characterization of a human-mouse chimeric antibody against the extracellular domain of claudin-1 for cancer therapy using a mouse model.2016
- Author(s)
  Hashimoto Y, Tada M, Iida M, Nagase S, Hata T, Watari A, Okada Y, Doi T, Fukasawa M, Yagi K, Kondoh M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 477(1) Issue: 1 Pages: 91-95
- DOI
  10.1016/j.bbrc.2016.06.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293014, KAKENHI-PROJECT-16K08370, KAKENHI-PROJECT-15J10065
[Journal Article] Expression of the Robo4 receptor in endothelial cells is regulated by two AP-1 protein complexes.2015
- Author(s)
  Okada Y, Naruse H, Tanaka T, Funahashi N, Regan ER, Yamakawa K, Hino N, Ishimoto K, Doi T, Aird WC.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 467(4) Issue: 4 Pages: 987-991
- DOI
  10.1016/j.bbrc.2015.10.029
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16537, KAKENHI-PROJECT-26870346, KAKENHI-PROJECT-26293014
[Journal Article] Regulation of Endothelial Cell-specific Robo4 Gene Expression by DNA Methylation and Non-lineage Specific Transcription Factors2014
- Author(s)
  Okada Y
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 134 Issue: 7 Pages: 817-821
- DOI
  10.1248/yakushi.13-00258
- NAID
  130004756442
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2014-07-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670056, KAKENHI-PROJECT-26293014
[Journal Article] Endothelial cell-specific expression of roundabout 4 is regulated by differential DNA methylation of the proximal promoter2014
- Author(s)
  Okada, Y., Funahashi, N., Tanaka, T., Nishiyama, Y., Yuan, L., Shirakura, K., Turjman, A. S., Kano, Y., Naruse, H., Suzuki, A., Sakai, M., Zhixia, J., Kitajima, K., Ishimoto, K., Hino, N., Kondoh, M., Mukai, Y., Nakagawa, S., Garcia-Cardena, G., Aird, W. C., Doi, T.
- Journal Title
  
  Arterioscler Thromb. Vasc. Biol.
  
  Volume: 34 Issue: 7 Pages: 1531-1538
- DOI
  10.1161/atvbaha.114.303818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670023, KAKENHI-PROJECT-25670056, KAKENHI-PROJECT-26293014, KAKENHI-PROJECT-26713007, KAKENHI-PROJECT-26870346
[Journal Article] Regulation of endothelial cell-specific Robo4 gene expression by DNA methylation and non-lineage specific transcription factors.2014
- Author(s)
  Yoshiaki Okada
- Journal Title
  
  Yakugaku Zasshi.
  
  Volume: in press
- NAID
  130004756442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670056
[Journal Article] RUNX1, but not its familial platelet disorder mutants, synergistically activates PF4 gene expression in combination with ETS family proteins.2013
- Author(s)
  Yoshiaki Okada
- Journal Title
  
  J Thromb Haemost.
  
  Volume: 11（9） Issue: 9 Pages: 1742-50
- DOI
  10.1111/jth.12355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670056
[Journal Article] An induced pluripotent stem cell-mediated and integration-free factor VIII expression system2013
- Author(s)
  Yakura Y, Ishihara C, Kurosaki H, Kazuki Y, Komatsu N, Okada Y, Doi T, Takeya H, Oshimura M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: Vol.431 Pages: 336-341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659040
[Journal Article] Transcriptional regulation of the endothelial cell-specific receptor, Robo42012
- Author(s)
  Okada Yoshiaki
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 132 Pages: 1045-1049
- NAID
  130001888723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659040
[Journal Article] Embryonic stem cell differentiation system for evaluating gene functions involved in physiological megakaryocytic differentiation2012
- Author(s)
  Okada Yoshiaki
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 419 Issue: 3 Pages: 477-481
- DOI
  10.1016/j.bbrc.2012.02.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790066, KAKENHI-PROJECT-23659040
[Journal Article] Transcriptional regulation of the endothelial cell-specific receptor, Robo42012
- Author(s)
  Okada Y
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: Vol.132 Pages: 1045-1049
- NAID
  130001888723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659040
[Journal Article] Embryonic stem cell differentiation system for evaluating gene functions involved in physiological megakaryocytic differentiation2012
- Author(s)
  Okada Y, Yonekura M, Watanabe M, Nakai T, Wakimura A, Shimizu M, Kamikawa Y, Kitayama M, Kitajima K, Aird WC, Doi T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: Vol.419 Pages: 477-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659040
[Journal Article] Embryonic stem cell differentiation system for evaluating gene functions involved in physiological megakaryocytic differentiation2012
- Author(s)
  Okada Y, Yonekura M, Watanabe M, Nakai T, Wakimura A, Shimizu M, Kamikawa Y, Kitayama M, Kitajima K, Aird WC, Doi T
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: Vol.419 Pages: 477-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790066
[Journal Article] Vascular bed specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle2011
- Author(s)
  Ju Liu, Yoshiaki Okada
- Journal Title
  
  Blood
  
  Volume: 117 Pages: 342-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790066
[Journal Article] Multiple ETS Family Proteins Regulate PF4 Gene Expression by Binding to the Same ETS Binding Site2011
- Author(s)
  Okada Y, Nobori H, Shimizu M, Watanabe M, Yonekura M, Nakai T, Kamikawa Y, Wakimura A, Funahashi N, Naruse H, Watanabe A, Yamasaki D, Fukada S, Yasui K, Matsumoto K, Sato T, Kitajima K, Nakano T, Aird WC, Doi T
- Journal Title
  
  PLoS ONE
  
  Volume: Vol.9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790066
[Journal Article] New Protein Purification System Using Gold-Magnetic Beads and a Novel Peptide Tag, "the Methionine Tag"2011
- Author(s)
  Okada Yoshiaki
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 22(5) Issue: 5 Pages: 887-93
- DOI
  10.1021/bc100429d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790066, KAKENHI-PROJECT-23659040
[Journal Article] Multiple ETS Family Proteins Regulate PF4 Gene Expression by Binding to the Same ETS Binding Site2011
- Author(s)
  Okada Yoshiaki
- Journal Title
  
  PLoS ONE
  
  Volume: 6(9) Issue: 9 Pages: e24837-e24837
- DOI
  10.1371/journal.pone.0024837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790066, KAKENHI-PROJECT-23659040
[Journal Article] New Protein Purification System Using Gold-Magnetic Beads and a Novel Peptide Tag, "the Methionine Tag"2011
- Author(s)
  Okada Y, Takano TY, Kobayashi N, Hayashi A, Yonekura M, NishiyamaY, Abe T, Yoshida T, Yamamoto TA, Seino S, Doi T
- Journal Title
  
  Bioconjug. Chem
  
  Volume: Vol.22 Pages: 887-893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659040
[Journal Article] Multiple ETS Family Proteins Regulate PF4 GeneExpression by Binding to the Same ETS Binding Site2011
- Author(s)
  Okada Y, Nobori H, Shimizu M, Watanabe M, Yonekura M, Nakai T, Kamikawa Y, Wakimura A, Funahashi N, Naruse H, Watanabe A, Yamasaki D, Fukada S, Yasui K, Matsumoto K, Sato T, Kitajima K, Nakano T, Aird WC, Doi T
- Journal Title
  
  PLoS One
  
  Volume: Vol.6 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659040
[Journal Article] New Protein Purification System Using Gold-Magnetic Beads and a Novel Peptide Tag," the Methionine Tag"2011
- Author(s)
  Okada Y, Takano TY, Kobayashi N, Hayashi A, Yonekura M, Nishiyama Y, Abe T, Yoshida T, Yamamoto TA, Seino S, Doi T
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: Vol.22 Pages: 887-893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790066
[Journal Article] Vascular bed specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle2011
- Author(s)
  Liu J, Yuan L, Molema G, Regan E, Janes L, Beeler D, Spokes KC, Okada Y, Minami T, Oettgen P, Aird WC
- Journal Title
  
  Blood
  
  Volume: Vol.117 Pages: 342-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790066
[Journal Article] Creation of a lysine-deficient LIGHT mutant with the capacity for site-specific PEGylation and low affinity for a decoy receptor.2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 393(4) Pages: 888-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] in vitroとin vivoで異なるレポータージーンアッセイの結果2010
- Author(s)
  岡田欣晃
- Journal Title
  
  生産と技術 62
  
  Pages: 51-56
- NAID
  40017231022
- Data Source
  KAKENHI-PROJECT-19390022
[Journal Article] Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy.2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biomaterials. 31(12)
  
  Pages: 3357-3363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Simple PEG conjugation of SPIO via an Au-S bond improves its tumor targeting potency as a novel MR tumor imaging agent.2010
- Author(s)
  Kojima H, Mukai Y, Yoshikawa M, Kamei K, Yoshikawa T, Morita M, Inubushi T, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S.
- Journal Title
  
  Bioconjug Chem.
  
  Volume: 21(6) Pages: 1026-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Creation of a lysine-deficient LIGHT mutant with the capacity for site-specific PEGylation and low affinity for a decoy receptor.2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda SI, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S
- Journal Title
  
  Biochem Biophys Res Commun. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Creation of lysine-deficient mutant lymphotoxin-alpha with recepor selectivity by using a phage display system.2010
- Author(s)
  Yoshioka Y, Watanabe H, Morishige T, Yao X, Ikemizu S, Nagao C, Ahmad S, Mizuguchi K, Tsunoda SI, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biomaterials. 31(7)
  
  Pages: 1935-1943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Simple PEG Conjugation of SPIO via an Au-S Bond Improves Its Tumor Targeting Potency as a Novel MR Tumor Imaging Agent.2010
- Author(s)
  Kojima H, Mukai Y, Yoshikawa M, Kamei K, Yoshikawa T, Morita M, Inubushi T, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S,
- Journal Title
  
  Bioconjug Chem. 21(6)
  
  Pages: 1026-1031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy.2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biomaterials
  
  Volume: 31(12) Pages: 3357-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] in vitroとin vivoで異なるレポータージーンアッセイの結果2010
- Author(s)
  岡田欣晃、土井健史
- Journal Title
  
  生産と技術 62巻
  
  Pages: 51-56
- NAID
  40017231022
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletalmuscle.2010
- Author(s)
  Liu J, Yuan L, Molema I, Regan E, Janes L, Beeler D, Spokes K, Okada Y, Minami T, Oettgen P, Aird WC
- Journal Title
  
  Blood
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] in vitroとin vivoで異なるレポータージーンアッセイの結果2010
- Author(s)
  岡田欣晃
- Journal Title
  
  生産と技術 62
  
  Pages: 51-56
- NAID
  40017231022
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] Tumor-targeting CTL expressing a single-chain Fv specific for VEGFR2.2010
- Author(s)
  Kanagawa N, Yanagawa T, Mukai Y, Yoshioka Y, Okada N, Nakagawa S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 393(4) Pages: 888-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletalmuscle2010
- Author(s)
  Liu J, Yuan L, Molema I, Regan E, Janes L, Beeler D, Spokes K, Okada Y, Minami T, Oettgen P, Aird WC
- Journal Title
  
  Blood (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] in vitroとin vivoで異なるレポータージーンアッセイの結果2010
- Author(s)
  岡田欣晃、土井健史
- Journal Title
  
  生産と技術 62巻
  
  Pages: 51-56
- NAID
  40017231022
- Data Source
  KAKENHI-PROJECT-19390022
[Journal Article] in vitroとin vivoで異なるレポータージーンアッセイの結果2010
- Author(s)
  岡田欣晃、土井健史
- Journal Title
  
  生産と技術 62
  
  Pages: 51-56
- NAID
  40017231022
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] 血管内皮細胞の遺伝子発現制御研究からみたin vivoプロモーター解析の重要性2009
- Author(s)
  岡田欣晃、土井健史
- Journal Title
  
  生化学 81
  
  Pages: 117-121
- NAID
  10024915912
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR12009
- Author(s)
  Baek KH, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, Lensch MW, Park IH, Yoon SS, Minami T, Korenberg JR, Foikman J, Daley GQ, Aird WC, Galdzicki Z, Ryeom S.
- Journal Title
  
  Nature 459
  
  Pages: 1126-1130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] A +220 GATA motif mediates basal but not endotoxin-repressible expression of the von Willebrand factor promoter in Hprt-targeted transgenic mice2009
- Author(s)
  J. Liu, Y. Kanki, Y. Okada, E. Jin, K. Yano, S.-C. Shih, T. Minami, W.C. Aird
- Journal Title
  
  J. Thromb. Haemost Vol.284
  
  Pages: 22195-22205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390022
[Journal Article] LIGHT protein suppresses tumor growth by augmentation of immune response.2009
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Watanabe H, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Immunol Lett. 127(1)
  
  Pages: 33-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] 血管内皮細胞の遺伝子発現制御研究からみたin vivoプロモーター解析の重要性2009
- Author(s)
  岡田欣晃, 土井健史
- Journal Title
  
  生化学 80巻
  
  Pages: 117-121
- NAID
  10024915912
- Data Source
  KAKENHI-PROJECT-19390022
[Journal Article] Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.2009
- Author(s)
  Baek KH, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, Lensch MW, Park IH, Yoon SS, Minami T, Korenberg JR, Folkman J, Daley GQ, Aird WC, Galdzicki Z, Ryeom S
- Journal Title
  
  Nature. 459(7250)
  
  Pages: 1126-1130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Differential roles for ETS, CREB and EGR binding sites in mediating VEGF receptor 1 expression in vivo2009
- Author(s)
  E. Jin, J. Liu, J. Suehiro, L. Yaun, Y. Okada, V. Nikolova-Krstevski, K. Yano, L. Janes, D. Beeler, K. Spokes, E. Regan, S.C. Shih, P. Oettgen, T. Minami, W.C. Aird
- Journal Title
  
  Blood Vol.114
  
  Pages: 5557-5566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390022
[Journal Article] Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR12009
- Author(s)
  K.H. Baek, A. Zaslavsky, R.C. Lynch, C. Britt, Y. Okada, R.J. Siarey, M.W. Lensch, I.H. Park, S.S. Yoon, T. Minami, J.R. Korenberg, J. Folkman, G.Q. Daley, W.C. Aird, Z. Galdzicki, S. Ryeom
- Journal Title
  
  Nature Vol.459
  
  Pages: 1126-1130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] 血管内皮細胞の遺伝子発現制御研究からみたin vivoプロモーター解析の重要性2009
- Author(s)
  岡田欣晃
- Journal Title
  
  生化学 81
  
  Pages: 117-121
- NAID
  10024915912
- Data Source
  KAKENHI-PROJECT-19390022
[Journal Article] A +220 GATA motif mediates basal but not endotoxin-repressible expression of the von Willebrand factor promoter in Hprt-targeted transgenic mice2009
- Author(s)
  J. Liu, Y. Kanki, Y. Okada, E. Jin, K. Yano, S. -C. Shih, T. Minami, W.C. Aird
- Journal Title
  
  J. Thromb. Haemost. Vol.7
  
  Pages: 1384-1392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] Differential. roles for ETS, CREB and EGR binding sites in mediating VEGF receptor 1 expression in vivo2009
- Author(s)
  Jin E, Liu J, Suehiro J, Yuan L, Okada Y, Nikolova-Krstevski V, Yano K, Janes L, Beeler D, Spokes KC, Li D, Regan E, Shih SC, Oettgen P, Minami T, Aird WC.
- Journal Title
  
  Blood 114
  
  Pages: 5557-5566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] A+220 GATA motif mediates basal but not endotoxin-repressible expression of the von Willebrand factor promoter in Hprt-targeted transgenic mice2009
- Author(s)
  Liu J, Kanki Y, Okada Y. Jin E, Yano K, Shih SC, Minami T, Aird WC.
- Journal Title
  
  Journal of thrombosis and haemostasis 284
  
  Pages: 22195-22205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Direct cell-entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery.2009
- Author(s)
  Kamei K, Mukai Y, Kojima H, Yoshikawa T, Yoshikawa M, Kiyohara G, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S,
- Journal Title
  
  Biomaterials. 30(9)
  
  Pages: 1809-1814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] 血管内皮細胞の遺伝子発現制御研究からみたin vivoプロモーター解析の重要性2009
- Author(s)
  岡田欣晃、土井健史
- Journal Title
  
  生化学 81巻
  
  Pages: 117-121
- NAID
  10024915912
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] Differential roles for ETS, CREB and EGR binding sites in mediating VEGF receptor 1 expression in vivo2009
- Author(s)
  E. Jin, J. Liu, J. Suehiro, L. Yaun, Y. Okada, V. Nikolova-Krstevski, K. Yano, L. Janes, D. Beeler, K.C. Spokes, D. Li, E. Regan, S.C. Shih, P. Oettgen, T. Minami, W.C. Aird
- Journal Title
  
  Blood Vol.114
  
  Pages: 5557-5566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR12009
- Author(s)
  K.H. Baek, A. Zaslavsky, R.C. Lynch, C. Britt, Y. Okada, R.J. Siarey, M.W. Lensch, I.H. Park, S.S. Yoon, T. Minami, J.R. Korenberg, J. Folkman, G.Q. Daley, W.C. Aird, Z. Galdzicki, S. Ryeom
- Journal Title
  
  Nature Vol.459
  
  Pages: 1126-1130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390022
[Journal Article] Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery2009
- Author(s)
  Kamei K, Mukai Y, Kojima H, Yoshikawa T, Yoshikawa M, Kiyohara G, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S.
- Journal Title
  
  Biomaterials 30
  
  Pages: 1809-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] 血管内皮細胞の遺伝子発現制御研究からみたin vivoプロモーター解析の重要性2009
- Author(s)
  岡田欣晃
- Journal Title
  
  生化学 81
  
  Pages: 117-121
- NAID
  10024915912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] Elevated levels of placental growth factor represent anadaptive host response in sepsis2008
- Author(s)
  Yano K, Okada Y, Beldi G, Shih SC, Bodyak N, Okada H, Kang PM, Luscirtskas W, Robson SC, Carmeliet P, Karumanchi SA, Aird WC.
- Journal Title
  
  J Exp Med 205
  
  Pages: 2623-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo2008
- Author(s)
  Yoshiaki Okada
- Journal Title
  
  Blood 112
  
  Pages: 2336-2339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390022
[Journal Article] A GABP-binding element in the Robo 4 promoter is necessary for endothelial expression in vivo2008
- Author(s)
  Okada Y, Jin E, Nikolova-Krstevski V, Yano K, Liu J, Beeler D, Spokes K, Kitayama M, Funahashi N, Doi T, Janes L, Minami T, Oettgen P, Aird WC.
- Journal Title
  
  Blood 112
  
  Pages: 2336-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Ligand-independent assembly of purified soluble magic roundabout (Robo4), a tumor-specific endothelial marker2008
- Author(s)
  Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda S, Tsutsumi Y, Okada N, Aird WC, Doi T, Nakagawa S.
- Journal Title
  
  Protein Expr Purif 61
  
  Pages: 78-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo2008
- Author(s)
  Y. Okada, E. Jin, V. Nikolova-Krstevski, K. Yano, J. Liu, D. Beeler, K. Spokes, M. Kitayama, N. Funahashi, T. Doi, L. Janes, T. Minami, P. Oettgen, W.C. Aird
- Journal Title
  
  Blood Vol.112
  
  Pages: 2336-2339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] Elevated levels of placental growth factor represent an adaptive host response in sepsis2008
- Author(s)
  Yano K, Okada Y, Beldi G, Shih SC, Bodyak N, Okada H, Kang PM, Luscinskas W, Robson SC, Carmeliet P, Karumanchi SA, Aird WC.
- Journal Title
  
  J Exp Med 205
  
  Pages: 2623-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo2008
- Author(s)
  Okada Y, Jin E, Nikolova-Krstevski V, Yano K, Liu J, Beeler D, Spokes K, Kitayama M, Funahashi N, Doi T, Janes L, Minami T, Oettgen P, Aird WC.
- Journal Title
  
  Blood 112
  
  Pages: 2336-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] Ligand-independent assembly of purified soluble magic roundabout (Robo4), a tumor-specific endothelial marker2008
- Author(s)
  Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda S, Tsutsumi Y, Okada N, Aird WC, Doi T, NakaEawa S.
- Journal Title
  
  Protein Expr Purif. 61
  
  Pages: 78-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo2008
- Author(s)
  Y. Okada, E. Jin, V. Nikolova-Krstevski, K. Yano, J. Liu, D. Beeler, K. Spokes, M. Kitayama, N. Funahashi, T. Doi, L. Janes, T. Minami, P. Oettgen, W.C. Aird
- Journal Title
  
  Blood Vol.112
  
  Pages: 2336-2339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390022
[Journal Article] A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.2008
- Author(s)
  Okada Y, Jin E, Nikolova-Krstevski V, Yano K, Liu J, Beeler D, Spokes K, Kitayama M, Funahashi N, Doi T, Janes L, Minami T, Oettgen P, Aird WC.
- Journal Title
  
  Blood. 112(6)
  
  Pages: 2336-2339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Elevated levels of placental growth factor represent an adaptive host response in sepsis2008
- Author(s)
  K. Yano, Y. Okada, G. Beldi, S.C. Shih, N. Bodyak, H. Okada, P.M. Kang, W. Luscinskas, S.C. Robson, P. Carmeliet, S.A. Karumanchi, W.C. Aird
- Journal Title
  
  J Exp Med. Vol.205
  
  Pages: 2623-2631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] Ligand-independent assembly of purified soluble magic roundabout (Robo4), a tumor-specific endothelial marker2008
- Author(s)
  M. Yoshikawa, Y. Mukai, Y. Okada, Y. Yoshioka, S. Tsunoda, Y. Tsutsumi, N. Okada, W.C. Aird, T. Doi, S. Nakagawa
- Journal Title
  
  Protein Expr Purif. Vol.61
  
  Pages: 78-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790064
[Journal Article] A Three-Kilobase Fragment of the Human Robo4 Promoter Directs Cell Type-Specific Expression in Endothelium2007
- Author(s)
  Y. Okada, K. Yano, E. Jin, N. Funahashi, M. Kitayama, T. Doi, K. Spokes, D.L. Beeler, S-C. Shih, H. Okada, T.A. Danilov, E. Maynard, T. Minami, P. Oettgen, W.C. Aird
- Journal Title
  
  Circulation Research Vol.100
  
  Pages: 1712-1722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390022
[Journal Article] A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium.2007
- Author(s)
  Yoshiaki Okada
- Journal Title
  
  Circulation Research 100(12)
  
  Pages: 1712-1722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890117
[Journal Article] A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium.2007
- Author(s)
  Yoshiaki Okada
- Journal Title
  
  Circulation Research 100(12)
  
  Pages: 1712-1722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390022
[Patent] 血管内皮バリア破綻の阻害剤及びその使用2023
- Inventor(s)
  高山和雄、岡田欣晃、他
- Industrial Property Rights Holder
  国立大学法人　大阪大学、京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-20H03382
[Patent] Claudin 5抗体、及びその抗体を含有する医薬品2016
- Inventor(s)
  岡田欣晃, 近藤昌夫, ほか
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] SARS-CoV-2が血管内皮バリア破綻を誘導する分子メカニズムの解析2024
- Author(s)
  早川玲菜、髙橋潤也、橋本里菜、渡邉幸夫、高山和雄、藤尾慈、岡田欣晃
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血管内皮バリアを標的とする重症感染症治療薬の開発2024
- Author(s)
  岡田欣晃
- Organizer
  日本薬学会第144年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] SARS-CoV-2による血管内皮バリア破綻機構の解明と抑制薬の同定2023
- Author(s)
  高橋潤也、橋本里菜、高山和雄、橘敬祐、近藤昌夫、藤尾慈、岡田欣晃
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血管を標的とする重症感染症・炎症性疾患治療薬の開発2023
- Author(s)
  岡田欣晃
- Organizer
  第20回鈴鹿病態薬学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血管内皮バリアを強化する戦略でのCOVID-19治療の可能性2023
- Author(s)
  森田真綾、高山和雄、吉岡靖雄、藤尾慈、岡田欣晃
- Organizer
  第１回新型コロナウイルス研究集会
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血管を標的とする疾患治療戦略の提案2023
- Author(s)
  岡田欣晃
- Organizer
  日本血管生物医学会第 3 回血管研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血管透過性を標的とする疾患治療薬の可能性2023
- Author(s)
  岡田欣晃
- Organizer
  第14回スクリーニング学研究会プレカンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血管透過性を標的とする重症感染症治療薬の開発2023
- Author(s)
  岡田欣晃
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血液脳関門を制御して脳内薬物送達を促進するClaudin-5結合分子の開発2023
- Author(s)
  井上采人、村岡康介、田口純平、冨田里美、竹田浩之、池田幸樹、土井健史、橘敬佑、近藤昌夫、細谷孝充、藤尾慈、岡田欣晃
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血管透過性を標的とする重症感染症治療薬の開発2023
- Author(s)
  岡田欣晃、高山和雄、吉岡靖雄、近藤昌夫、藤尾慈
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 重症感染症における血管内皮バリアの破綻と制御2023
- Author(s)
  岡田欣晃
- Organizer
  CVMW2023
- Invited
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] Upregulation of Robo4 reduces vascular permeability and mortality in endotoxemia and COVID-19 models2023
- Author(s)
  Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Rina Hashimoto, Hiroyasu Kidoya, Nobuyuki Takakura, Yoshiaki Kubota, Kazuo Takayama, Yasuo Yoshioka, Yasushi Fujio, Yoshiaki Okada
- Organizer
  ICoLA 2023/Asia-Australia Vascular Biology Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血管透過性抑制分子Robo4の発現を促進する重症感染症治療薬の開発2023
- Author(s)
  森田真綾、米田安希、徳納渚沙、正木辰実、橋本里菜、高山和雄、吉岡靖雄、藤尾慈、岡田欣晃
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 免疫細胞浸潤性の低い腫瘍（Cold tumor）に対する効果的ながん免疫療法の開発2023
- Author(s)
  加藤吏恵、宗像理紗、青枝大貴、小山正平、小俣大樹、鈴木悠乃、岡田欣晃、吉岡靖雄、鈴木　亮
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H04519
[Presentation] Development of small molecules that bind to Claudin-5 and control blood-brain barrier2023
- Author(s)
  Saito Inoue, Kousuke Muraoka, Jumpei Taguchi, Satomi Tomita, Hiroyuki Takeda, Takefumi Doi, Keisuke Tachibana, Masuo Kondoh, Takamitsu Hosoya, Yasushi Fujio, Yoshiaki Okada
- Organizer
  ICoLA 2023/Asia-Australia Vascular Biology Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血管内皮細胞間の接着を標的とする重症感染症治療薬の開発2023
- Author(s)
  岡田欣晃、高山和雄、吉岡靖雄、近藤昌夫、藤尾慈
- Organizer
  生理学研究所　上皮細胞研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 血管安定化分子Robo4が炎症性疾患を緩和するメカニズムの解析2023
- Author(s)
  田中雅人、白倉圭佑、松井美紀、渡邉幸夫、髙山結衣、土井健史、高山和雄、藤尾慈、岡田欣晃
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] Robo4 が感染症病態の悪化を抑制する新規メカニズムの探索2023
- Author(s)
  髙山結衣、田中雅人、高山和雄、藤尾慈、岡田欣晃
- Organizer
  第73回日本薬学会関西支部　総会・大会
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 免疫抑制的な腫瘍内微小環境を有する腫瘍への効果的ながん免疫療法構築に向けた基礎的研究2022
- Author(s)
  宗像理紗、青枝大貴、小山正平、小俣大樹、丸山　保、鈴木悠乃、萩原芙美子、岡田欣晃、吉岡靖雄、鈴木　亮
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H04519
[Presentation] SARS-CoV-2による肺血管バリア機能の制御2022
- Author(s)
  岡田欣晃、高橋潤也、橋本里菜、藤尾慈、高山和雄
- Organizer
  CVMW2022 心血管代謝週間
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 免疫抑制的な環境を構築する腫瘍への抗腫瘍免疫誘導に関する検討2022
- Author(s)
  宗像理紗、小俣大樹、小山正平、岡田欣晃、吉岡靖雄、青枝大貴、鈴木　亮
- Organizer
  日本核酸医薬学会第7年会
- Data Source
  KAKENHI-PROJECT-20H04519
[Presentation] Development of type A CpG oligodeoxynucleotide loaded lipid nanoparticles as an adjuvant for cancer immunotherapy2022
- Author(s)
  宗像理紗、青枝大貴、小山正平、小俣大樹、鈴木悠乃、岡田欣晃、吉岡靖雄、鈴木　亮
- Organizer
  第16回次世代を担う若手のための医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-20H04519
[Presentation] マイクロバブルと超音波照射による固形がん組織の腫瘍微小環境変化を介した養子免疫療法の抗腫瘍効果増強に関する検討2022
- Author(s)
  鈴木　亮、丸山　保、宗像理紗、鈴木悠乃、小俣大樹、工藤信樹、小山正平、岡田欣晃
- Organizer
  日本ハイパーサーミア学会39回大会
- Data Source
  KAKENHI-PROJECT-20H04519
[Presentation] マイクロバブルと超音波併用による免疫微小環境の変化と養子免疫療法の抗腫瘍効果増強に関する基礎的検討2022
- Author(s)
  丸山　保、宗像理紗、小俣大樹、萩原芙美子、鈴木悠乃、小山正平、岡田欣晃、工藤信樹、鈴木　亮
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H04519
[Presentation] SARS-CoV-2が肺血管の内皮細胞バリアに与える影響の解析2022
- Author(s)
  高橋潤也、橋本里菜、高山和雄、藤尾慈、岡田欣晃
- Organizer
  第22回 Pharmaco-Hematology シンポジウム
- Data Source
  KAKENHI-PROJECT-20H03382
[Presentation] 固形がんに対する養子免疫療法とマイクロバブル-超音波併用による抗腫瘍効果の増強に関する検討2022
- Author(s)
  丸山　保、宗像理紗、小俣大樹、鈴木悠乃、小山正平、岡田欣晃、鈴木　亮
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-20H04519
[Presentation] 血管透過性を標的とする新戦略でのがん・炎症性疾患治療の可能性2021
- Author(s)
  岡田欣晃
- Organizer
  Angiogeneis & Immunology Research-Hepatocellular Carcinoma
- Invited
- Data Source
  KAKENHI-PROJECT-20H04519
[Presentation] 血管内皮細胞特異的タンパク質Robo4による炎症血管の透過性制御2019
- Author(s)
  岡田欣晃
- Organizer
  薬学会第１３９年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19487
[Presentation] HDAC阻害剤MS-275のガン転移モデルにおける二面性2019
- Author(s)
  岡田欣晃
- Organizer
  第5回血管生物若手研究会
- Data Source
  KAKENHI-PROJECT-17K19487
[Presentation] 脳内に効率よく薬を運ぶための新しい血液脳関門制御技術2019
- Author(s)
  岡田欣晃
- Organizer
  大阪大学新技術説明会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19487
[Presentation] ETV2, an endothelial master transcription factor, induces endothelial cell-specific gene expression via promoter demethylation.2018
- Author(s)
  Toru Tanaka, Kohei Izawa, Osamu Nakagawa, William C. Aird, Hiroyuki Mizuguchi, Kenji Kawabata, Takefumi Doi, Yoshiaki Okada
- Organizer
  The 16th Korea-Japan Joint Symposium on Vascular Bioloty
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19487
[Presentation] 血管内皮細胞特異的な遺伝子発現を生み出す転写・エピジェネティック因子複合体2018
- Author(s)
  岡田欣晃
- Organizer
  阪大医学系研究科若手研究フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-17K19487
[Presentation] 血管内皮細胞を生み出すエピジェネティクス機構とは？2018
- Author(s)
  岡田欣晃
- Organizer
  第13回関西バイオ創薬研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19487
[Presentation] ETV2-TET1/2 Complexes Induce Endothelial Cell-Specific Robo4 Expression via Promoter Demethylation2018
- Author(s)
  Tor Tanaka, Kohei Izawa, Osamu Nakagawa, William C. Aird, Hiroyuki Mizuguchi, Kenji Kawabata, Takefumi Doi, Yoshiaki Okada
- Organizer
  The 20th International Vacular Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19487
[Presentation] 血管内皮細胞特異的膜タンパク質Robo4の炎症における役割2018
- Author(s)
  白倉圭佑, 樫尾泰斗, 船津梨彩, William Aird, 土井健史, 岡田欣晃
- Organizer
  CVMW2018心血管代謝週間
- Data Source
  KAKENHI-PROJECT-17K19487
[Presentation] 2.血管内皮細胞特異的受容体Robo4が癌の増殖、転移、血管透過性に与える影響の解析2017
- Author(s)
  石破亮祐, 樫尾泰斗, 吉岡靖雄, 鈴木亮, 小山正平, 青枝大貴, 岡田欣晃, 土井健史
- Organizer
  第25回日本血管生物医学会学術集会/心血管代謝週間
- Data Source
  KAKENHI-PROJECT-17K19487
[Presentation] TNF-αはNF-κB経路を介して血管内皮細胞特異的受容体Robo4の発現を促進する2017
- Author(s)
  前河直樹, 田中亨, 樫尾泰斗, William C. Aird, 岡田欣晃, 土井健史
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  東北大学（宮城）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] 1.新規内皮細胞特異的複合体Robo4-TRAF7は炎症時の血管透過性亢進を抑制する2017
- Author(s)
  白倉圭佑, 石破亮祐, 樫尾泰斗, 船津梨彩, William C Aird, 岡田欣晃, 土井健史
- Organizer
  第25回日本血管生物医学会学術集会/心血管代謝週間
- Data Source
  KAKENHI-PROJECT-17K19487
[Presentation] 第二回血管生物医学会若手研究会2016
- Author(s)
  岡田欣晃
- Organizer
  Robo4発現抑制分子を用いた新規敗血症治療戦略の可能性
- Place of Presentation
  東北大学（宮城県）
- Year and Date
  2016-03-05
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] Novel anti-sepsis strategy targeting the endothelial cell-specific receptor Robo42016
- Author(s)
  Yoshiaki Okada, Keisuke Shirakura, Kiichiro Yano, Naoya Shigesada, Yu Fukushima, Ryosuke Ishiba, Taito Kashio, William C. Aird, Takefumi Doi
- Organizer
  第2 回春期特別日本血管生物医学会シンポジウム
- Place of Presentation
  大阪大学微生物病研究所（大阪府）
- Year and Date
  2016-06-03
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] 3.Roundabout4 suppresses TNFα-induced vascular hyperpermeability via TRAF72016
- Author(s)
  Keisuke Shirakura, Toru Tanaka, William C. Aird, Takefumi Doi, Yoshiaki Okada
- Organizer
  19th International Vascular Biology Meeting
- Place of Presentation
  ボストン（アメリカ）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] Robo4が炎症時の血管透過性を制御するメカニズムの解析2016
- Author(s)
  白倉圭佑, William Aird, 岡田欣晃, 土井健史
- Organizer
  第17回 Pharmaco-Hematology シンポジウム
- Place of Presentation
  帝京大学（東京）
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] Tricellular tight junction を標的とした新規バリア制御技術、angubindin-1 の開発2016
- Author(s)
  山本浩樹, 井口大輔, 早石知浩, Susanne M. KRUG, Michael FROMM, 渡利彰浩, 岡田欣晃, 竹田浩之, 永浜政博, 土井健史, 澤崎達也, 近藤昌夫, 八木清仁
- Organizer
  日本薬学会　第136年会
- Place of Presentation
  横浜（神奈川県）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] 血管内皮細胞特異的Robo4発現が生み出されるメカニズムの解明2016
- Author(s)
  田中亨, 岡村麻紀, 川端健二, 岡田欣晃, 土井健史
- Organizer
  第17回 Pharmaco-Hematology シンポジウム
- Place of Presentation
  帝京大学（東京）
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] Novel anti-sepsis strategy targeting the endothelial cell-specific receptor Robo42016
- Author(s)
  Yoshiaki Okada, Keisuke Shirakura, Kiichiro Yano, Naoya Shigesada, Yu Fukushima, Ryosuke Ishiba, Taito Kashio, William C. Aird, Takefumi Doi
- Organizer
  第２回春期特別日本血管生物医学会シンポジウム
- Place of Presentation
  大阪大学（大阪）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] 炎症下の血管透過性制御におけるRobo4の役割2016
- Author(s)
  岡田欣晃
- Organizer
  Kansai Vascular Biology Meeting 2016
- Place of Presentation
  ホテルグランビア大阪（大阪）
- Invited
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] Claudin を標的とした創薬基盤技術の開発～claudin-4 を標的としたがん治療戦略の有効性及び安全性の評価～2016
- Author(s)
  松田基, 橋本洋佑, 川東祐美, 畑智幸, 渡利彰浩, 近藤昌夫, 岡田欣晃，多田稔, 石井明子, 深澤征義, 土井健史, 八木清仁
- Organizer
  日本薬学会　第136年会
- Place of Presentation
  横浜（神奈川県）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] 血管内皮細胞特異的受容体を標的とする新規全身性炎症治療薬の開発2015
- Author(s)
  重定直弥、真鍋詩織、山本奈那、William Aird、岡田欣晃、土井健史
- Organizer
  第１４回次世代を担う若手ファーマ・バイオフォーラム2015
- Place of Presentation
  千葉大学亥鼻キャンパス(千葉県)
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] 血管内皮細胞特異的受容体Robo4の敗血症治療標的としての可能性2015
- Author(s)
  岡田欣晃
- Organizer
  日本血管生物医学会若手研究会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2015-02-06
- Data Source
  KAKENHI-PROJECT-25670056
[Presentation] Robo4プロモーターの血管内皮細胞特異的なDNAメチル化パターン形成に寄与する因子の探索2015
- Author(s)
  田中亨、間庭佑典、岡田淳雅、川端健二、Aird WC、岡田欣晃、土井健史
- Organizer
  第９回日本エピジェネティクス研究会年会
- Place of Presentation
  学術総合センター一橋講堂（東京都）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] 血管内皮細胞特異的受容体Robo4の敗血症治療標的としての可能性2015
- Author(s)
  岡田欣晃
- Organizer
  日本血管生物医学会若手研究会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2015-02-06
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] 血管内皮細胞特異的な遺伝子発現とDNAメチル化2015
- Author(s)
  岡田欣晃、William Aird、土井健史
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（兵庫）
- Year and Date
  2015-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-25670056
[Presentation] 血管内皮細胞特異的な遺伝子発現とDNAメチル化2015
- Author(s)
  岡田欣晃、William Aird、土井健史
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（兵庫）
- Year and Date
  2015-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] 血管内皮細胞特異的受容体Robo4 の炎症応答における役割2014
- Author(s)
  白倉圭佑、酒井美貴、福島優、真鍋詩織、William Aird、岡田欣晃、土井健史
- Organizer
  第15回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  名古屋市立大学大学院薬学研究科（愛知）
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25670056
[Presentation] 血管内皮細胞特異的受容体Robo4 の炎症応答における役割2014
- Author(s)
  白倉圭佑、酒井美貴、福島優、真鍋詩織、William Aird、岡田欣晃、土井健史
- Organizer
  第15回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  名古屋市立大学大学院薬学研究科（愛知）
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] DNA methylation of the proximal promoter regulates endothelial cell-specific Robo4 gene expression2014
- Author(s)
  Yoshiaki Okada, Nobuaki Funahashi, Yuji Nishiyama, Toru Tanaka, Keisuke Shirakura, Yusuke Maniwa, William C. Aird, Takefumi Doi
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] 血管内皮細胞特異的受容体Robo4 の血管透過性制御における役割2014
- Author(s)
  山内沙織、白倉圭佑、William C Aird、岡田欣晃、土井健史
- Organizer
  第64回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25670056
[Presentation] Roles of Endothelial cell specific receptor, Robo4 in inflammatory response2014
- Author(s)
  Keisuke Shirakura, Miki Sakai, Yu Fukushima, Shiori Manabe, William C. Aird, Yoshiaki Okada, Takefumi Doi
- Organizer
  第8回SKOシンポジウム
- Place of Presentation
  大阪大学銀杏会館（大阪）
- Year and Date
  2014-06-10
- Data Source
  KAKENHI-PROJECT-25670056
[Presentation] Robo4 発現抑制による炎症抑制機構の解析と敗血症治療薬開発への応用2014
- Author(s)
  真鍋詩織、山本奈那、Aird WC、岡田欣晃、土井健史
- Organizer
  第64回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25670056
[Presentation] 血管内皮細胞特異的受容体Robo4 の血管透過性制御における役割2014
- Author(s)
  山内沙織、白倉圭佑、William C Aird、岡田欣晃、土井健史
- Organizer
  第64回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] Roles of Endothelial cell specific receptor, Robo4 in inflammatory response2014
- Author(s)
  Keisuke Shirakura, Miki Sakai, Yu Fukushima, Shiori Manabe, William C. Aird, Yoshiaki Okada, Takefumi Doi
- Organizer
  第8回SKOシンポジウム
- Place of Presentation
  大阪大学銀杏会館（大阪）
- Year and Date
  2014-06-10
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] Robo4 発現抑制による炎症抑制機構の解析と敗血症治療薬開発への応用2014
- Author(s)
  真鍋詩織、山本奈那、Aird WC、岡田欣晃、土井健史
- Organizer
  第64回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-26293014
[Presentation] DNA methylation of the proximal promoter regulates endothelial cell-specific Robo4 gene expression2014
- Author(s)
  Yoshiaki Okada, Nobuaki Funahashi, Yuji Nishiyama, Toru Tanaka, Keisuke Shirakura, Yusuke Maniwa, William C. Aird, Takefumi Doi
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-25670056
[Presentation] Robo4遺伝子の組織特異的な発現を制御するDNA メチル化サイトについての解析2012
- Author(s)
  西山侑児、酒井美貴、鈴木綾乃、加納義浩、舟橋伸昭、岡田欣晃、土井健史
- Organizer
  第13回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  日本薬学会長井記念ホール(東京都)
- Year and Date
  2012-06-16
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation] DNA メチル化サイトへの点変異導入はRobo4プロモーターの組織特異性を失わせる2012
- Author(s)
  岡田欣晃、西山侑児、鈴木綾乃、酒井美貴、舟橋伸昭、加納義浩、William Aird、土井健史
- Place of Presentation
  学術総合センター(東京都)
- Year and Date
  2012-05-14
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation] 血管内皮細胞特異的遺伝子発現の制御メカニズム解析2012
- Author(s)
  岡田欣晃
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation] Robo4プロモーターの組織特異的なDNAメチル化パターンが決定されるメカニズムの解析2012
- Author(s)
  酒井美貴、西山侑児、舟橋伸昭、柿内康司、間庭佑典、岡田欣晃、土井健史
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation] Robo4 遺伝子の組織特異的な発現はDNA メチル化により制御される-血管内皮細胞特異的な遺伝子発現が生み出されるメカニズムとは-2012
- Author(s)
  岡田欣晃, William Aird, 土井健史
- Organizer
  第62回日本薬学会近畿支部総会・大会
- Place of Presentation
  武庫川女子大学薬学部(兵庫県)(招待講演)
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation] DNAメチル化はRobo4遺伝子を血管内皮細胞特異的に発現させる2011
- Author(s)
  岡田　欣晃
- Organizer
  第5回日本エピジェネティクス研究会年会
- Place of Presentation
  KKRホテル熊本（熊本県）
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation] DNA メチル化によるRobo4遺伝子の組織特異的発現の制御 Robo4 遺伝子はなぜ血管内皮細胞特異的に発現するのか-2011
- Author(s)
  岡田欣晃、西山侑児、鈴木綾乃、酒井美貴、舟橋伸昭、加納義浩、成瀬啓樹、William Aird、土井健史
- Organizer
  第61回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学ポートアイランドキャンパス(兵庫県)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation] 血管内皮細胞特異的に発現するRobo4遺伝子の発現は血管平滑筋細胞の共存により抑制される2011
- Author(s)
  鈴木綾乃, 成瀬啓樹, 舟橋伸昭, 西山侑児, 岡田欣晃, 土井健史
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] DNAメチル化によるRobo4遺伝子の組織特異的発現の制御2011
- Author(s)
  岡田欣晃
- Organizer
  第61回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学(神戸)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] DNAメチル化によるRobo4遺伝子の組織特異的発現の制御2011
- Author(s)
  岡田　欣晃
- Organizer
  第61回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学（兵庫県）
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation] 血小板第4因子遺伝子の-51ETSサイトを介した発現制御メカニズムについて2011
- Author(s)
  志水美己子, 神川悠子, 仲井友子, 渡邊美穂, 米倉正哲, 岡田欣晃, 土井健史
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] DNAメチル化はRobo4遺伝子を血管内皮細胞特異的に発現させる2011
- Author(s)
  岡田欣晃、舟橋伸昭、加納義浩、西山侑児、成瀬啓樹、鈴木綾乃、William Aird、土井健史
- Organizer
  第5回日本エピジェネティクス研究会年会
- Place of Presentation
  KKRホテル熊本
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] Robo4遺伝子の血管内皮細胞特異的な発現を担うエピジェネティックな遺伝子発現制御メカニズム2011
- Author(s)
  西山侑児, 舟橋伸昭, 成瀬啓樹, 鈴木綾乃, 岡田欣晃, 土井健史
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] Protein purification system using magnetic beads modified with gold nanoparticles2011
- Author(s)
  Seino S, Okada Y, Takano TY, Doi T, Koga Y, Takashi Nakagawa T, Yamamoto TA
- Organizer
  第35回日本磁気学会学術講演会(日本磁気学会国際シンポジウム)
- Place of Presentation
  朱鷺メッセ
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] DNAメチル化によるRobo4遺伝子の組織特異的発現の制御2011
- Author(s)
  岡田欣晃、西山侑児、鈴木綾乃、酒井美貴、舟橋伸昭、加納義浩、成瀬啓樹、William Aird、土井健史
- Organizer
  第61回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] DNAメチル化はRobo4遺伝子を血管内皮細胞特異的に発現させる2011
- Author(s)
  岡田欣晃、舟橋伸昭、加納義浩、西山侑児、成瀬啓樹、鈴木綾乃、William Aird、土井健史
- Organizer
  第5回日本エピジェネティクス研究会年会
- Place of Presentation
  KKRホテル熊本(熊本県)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation] DNAメチル化はRobo4遺伝子を血管内皮細胞特異的に発現させる2011
- Author(s)
  岡田欣晃
- Organizer
  第5回日本エピジェネティクス研究会年会
- Place of Presentation
  KKRホテル熊本(熊本)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] Robo4遺伝子が血管内皮細胞特異的に発現するメカニズムとは2010
- Author(s)
  岡田欣晃
- Organizer
  第11回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  日本薬学会長井記念ホール
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] 家族性血小板減少症患者にみられる変異型RUNX1の機能解析2010
- Author(s)
  渡邊美穂, 米倉正哲, 仲井友子, 登治謙, 志水美己子, 岡田欣晃, 土井健史
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山桃太郎アリーナ(岡山県)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-19390022
[Presentation] Robo4遺伝子が血管内皮細胞特異的に発現するメカニズムとは?2010
- Author(s)
  岡田欣晃
- Organizer
  第11回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  日本薬学会長井記念ホール
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] 血小板分化における野生型および変異型RUNX1の機能について2010
- Author(s)
  仲井友子、渡邊美穂、米倉正哲、志水美己子、神川悠子、岡田欣晃、土井健史
- Organizer
  BMB2010(第33回日本分子生物学会年会、第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] 血管内皮細胞特異的に発現するレセプターROBO4とSLITの相互作用解析2010
- Author(s)
  蒋志侠、鈴木綾乃、舟橋伸昭、加納義浩、成瀬啓樹、岡田欣晃、土井健史
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Immuno-conjugate製剤における抗体の細胞内侵入活性と抗腫瘍効果の連関解析2010
- Author(s)
  吉川舞、向洋平、堤康央、角田慎一、吉岡靖雄、岡田直貴、中川晋作
- Organizer
  第26回日本DDS学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] ROBO4の血管内皮細胞特異的発現制御とDNAメチル化の関連性の解析2010
- Author(s)
  加納義浩, 舟橋伸昭, 成瀬啓樹, 蒋志侠, 鈴木綾乃, 岡田欣晃, 土井健史
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山桃太郎アリーナ(岡山県)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] 血管内皮細胞特異的に発現するレセプターROBO4とSLITの相互作用解析2010
- Author(s)
  蒋志侠, 鈴木綾乃, 舟橋伸昭, 加納義浩, 成瀬啓樹, 岡田欣晃, 土井健史
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山桃太郎アリーナ(岡山県)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] Gold/ Iron-oxide composite nanoparticles as new type of magnetic nanocarrier for in-vivo and in-vitro applications2010
- Author(s)
  Seino S, Koga Y, Mukai Y, Okada Y, Nakagawa T, Yamamoto TA., Doi T,Nakagawa Shinsaku
- Organizer
  Pacifichem2010
- Place of Presentation
  ホノルル
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] 血小板系列特異的に特定の遺伝子を発現できるES細胞分化系の構築2010
- Author(s)
  米倉正哲, 渡邊美穂, 仲井友子, 志水美己子, 神川悠子, 岡田欣晃, 土井健史
- Organizer
  BMB2010(第33回日本分子生物学会年会、第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] Immune-conjugate製剤の開発に適う細胞内侵入抗体の効率的創製法の確立2010
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 新規腫瘍MRI造影剤としてのPEG化金SPIOの有用性評価2010
- Author(s)
  松尾奈緒美、向洋平、小島拓記、吉川舞、清野智史、山本孝夫、吉岡靖雄、岡田直貴、高島庄太夫、中川晋作
- Organizer
  第26回日本DDS学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 血管新生関連因子Robo4の発現制御メカニズムの解析2010
- Author(s)
  成瀬啓樹、蒋志侠、舟橋伸昭、志水美己子、鈴木綾乃、西山侑児、William Aird、岡田欣晃、土井健史
- Organizer
  BMB2010(第33回日本分子生物学会年会、第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] 金/酸化鉄磁性複合ナノ粒子を用いたタンパク質の精製2010
- Author(s)
  清野智史、澤祐司、中川貴、古賀雄一、岡田欣晃、土井健史、中川晋作、山本孝夫
- Organizer
  第34回日本磁気学会学術講演会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22790066
[Presentation] ROBO4の血管内皮細胞特異的発現制御とDNAメチル化の関連性の解析2010
- Author(s)
  加納義浩、舟橋伸昭、成瀬啓樹、蒋志侠、鈴木綾乃、岡田欣晃、土井健史
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Robo4プロモーターに存在するGABP結合配列のin vivoにおける重要性2009
- Author(s)
  岡田欣晃、金恩京、北山美絵、舟橋伸昭、矢野喜一郎、Aird WC、土井健史
- Organizer
  第10回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 血管内皮細胞に特異的に発現するRobo4遺伝子の新規転写調節配列の同定と解析2009
- Author(s)
  成瀬啓樹、蒋志侠、舟橋伸昭、加納義浩、鈴木綾乃、William Aird、岡田欣晃、土井健史
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] High-throughput screening method of "Cell-internalizing monoclonal antibodies", potent anti-tumor drug delivery carriers2009
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Design of tumor targeting magnetic resonance imaging (MRI) agent based on gold/iron-oxide composite nanoparticle.2009
- Author(s)
  Kojima H, Mukai Y, Kamei K, Seino S, Morita M, Inubushi T, Yoshioka Y, Okada N, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 血管内皮細胞に特異的に発現するRobo4遺伝子の新規転写調節配列の同定と解析2009
- Author(s)
  成瀬啓樹、蒋志侠、舟橋伸昭、加納義浩、鈴木綾乃、Aird WC、岡田欣晃、土井健史
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Ligand independent assembly of purified soluble Magic Roundabout (Robo4), a tumor-specific endothelial marker2009
- Author(s)
  Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda S, Tsutsumi Y, Okada N, Aird WC, Doi T, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Design of tumor targeting magnetic resonance imaging (MRI) agent based on gold/iron-oxide composite nanoparticle.2009
- Author(s)
  Kojima H, Mukai Y, Kamei K, Seino S, Morita M, Inubushi T, Yoshioka Y, Okada N, Nakagawa S.
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery2009
- Author(s)
  Mukai Y, Kojima H, Yoshikawa T, Kamei K, Yoshikawa M, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 血管内皮細胞に発現するレセプターROBO4のリガンドの同定2009
- Author(s)
  蒋志侠, 舟橋伸昭, 加納義浩, 成瀬啓樹, 岡田欣晃, 土井健史
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] Robo4遺伝子の血管内皮細胞特異的な発現とDNAメチル化との関連2009
- Author(s)
  舟橋伸昭、成瀬啓樹、加納義浩、Jiang Zhixia、鈴木綾乃, 岡田欣晃、土井健史
- Organizer
  第8回次世代を担う若手ファーマバイオフォーラム2009
- Place of Presentation
  名古屋市立大学田辺通キャンパス(愛知県)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] 血管内皮細胞と非血管内皮細胞におけるROBO4プロモーターのメチル化パターンの相違2009
- Author(s)
  加納義浩、舟橋伸昭、成瀬啓樹、蒋志侠、岡田欣晃、土井健史
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] 微細超常磁性酸化鉄粒子(USPIO)をコアとしたPEG化金磁性ナノ粒子の創製とそのMRI腫瘍造影剤としての有用性評価2009
- Author(s)
  小島拓記、向洋平、森田将史、犬伏俊郎、山本孝夫、吉岡靖雄、岡田直貴、清野智史、中川晋作
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Antibody-drug conjugateの開発に適う細胞内侵入抗体の効率的探索法2009
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  第8回ファーマ・バイオフォーラム
- Place of Presentation
  名古屋
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 51 ETSサイトを介するPF4遺伝子の発現制御メカニズムの解明2009
- Author(s)
  登治謙, 渡邊美穂, 米倉正哲, 志水美己子, 仲井友子, 岡田欣晃, 土井健史
- Organizer
  第8回次世代を担う若手ファーマバイオフォーラム2009
- Place of Presentation
  名古屋市立大学田辺通キャンパス(愛知県)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-19390022
[Presentation] Robo4遺伝子の血管内皮細胞特異的な発現とDNAメチル化との関連2009
- Author(s)
  舟橋伸昭、成瀬啓樹、加納義浩、Ziang Zhixia、鈴木綾乃、岡田欣晃、土井健史
- Organizer
  第8回次世代を担う若手ファーマバイオフォーラム2009
- Place of Presentation
  名古屋
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Robo4プロモーターに存在するGABP結合配列のin vivoにおける重要性2009
- Author(s)
  岡田欣晃、金恩京、北山美絵、舟橋伸昭、矢野喜一郎、William Aird、土井健史
- Organizer
  第10回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  日本薬学会長井記念ホール(東京都)
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] -51 ETSサイトを介する血小板第4因子遺伝子の発現制御機構の解析2009
- Author(s)
  登治謙, 渡邊美穂, 米倉正哲, 岡田欣晃, 土井健史
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19390022
[Presentation] immuno-conjugate製剤の開発に適う細胞内侵入抗体の効率的創製法の確立2009
- Author(s)
  吉川舞、向洋平、久保貴、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Ligand independent assembly of purified soluble Magic Roundabout (Robo4), a tumor-specific endothelial marker2009
- Author(s)
  Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda S, Tsutsumi Y, Okada N, Aird WC, Doi T, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 血小板第4因子遺伝子の発現制御における-51 ETSサイトの役割2009
- Author(s)
  登治謙, 渡邊美穂, 米倉正哲, 岡田欣晃, 土井健史
- Organizer
  第10回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  日本薬学会長井記念ホール(東京都)
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-19390022
[Presentation] Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery2009
- Author(s)
  Mukai Y, Kojima H, Yoshikawa T, Kamei K, Yoshikawa M, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 血管内皮細胞と非血管内皮細胞におけるROBO4プロモーターのDNAメチル化状態の相違2008
- Author(s)
  舟橋伸昭、成瀬啓樹、加納義浩、Zhixia Jiang、岡田欣晃、土井健史
- Organizer
  第81回日本生化学会大会第31回日本分子生物学会年会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] Difference of the methylation pattern of the Robo4 promoter between endothelial cell and non-endothelial cell2008
- Author(s)
  Yoshiaki Okada, Nobuaki Funahashi, Yoshihiro Kano, Hiroki Naruse, Zhixia Jiang, Enjing Jin, kiichiro Yano, William Aird, Takefumi Doi
- Organizer
  The 6^<th> Korea-Japan Joint Symposium on Vascular Biology and The 16th Annual Meeting of the Japan Vascular Biology and Medicine Organization JOINT MEETING
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] Difference of the methy lation pattern of the Robo4 promoter bet ween endothelial cell and non-endothelial cell2008
- Author(s)
  Yoshiaki Okada, Nobuaki Funahashi, Yos hihiro Kano, Hiroki Naruse, Zhixia Jiang, Enjing Jin, Kiichiro Yano, William Aird, Takefumi Doi
- Organizer
  The 6th Korea-Japan Joint Symposiu m on Vascular Biology and The 16th A nnual Meeting of the Japan Vascular Bio logy and Medicine Organization JOINTM EETING
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] 金磁性ナノ粒子が可能とする遺伝子導入技術の確立2008
- Author(s)
  小島拓記, 向洋平, 亀井数正, 吉川友章, 吉岡靖雄, 清野智史, 山本孝夫, 岡田直貴, 中川晋作
- Organizer
  第24回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 新規腫瘍MR造影剤の開発を目指したPEG化金磁性ナノ粒子の創製2008
- Author(s)
  亀井数正, 向洋平, 小島石記, 森田将史, 犬伏俊郎, 清野智史, 山本孝夫, 吉岡靖雄, 岡田直貴, 中川晋作
- Organizer
  第24回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 新規血管内皮細胞マーカーRobo4のin vivo発現制御機構解析2008
- Author(s)
  岡田欣晃、金恩京、北山美絵、舟橋伸昭、矢野喜一郎、William Aird、土井健史
- Organizer
  第81回日本生化学会大会第31回日本分子生物学会年会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 新規血管内皮細胞マーカーRobo4のi n vivo発現制御機構解析2008
- Author(s)
  岡田欣晃、金恩京、北山美絵、舟橋伸昭、矢野喜一郎、William Aird、土井健史
- Organizer
  第81回日本生化学会大会第31回日本分子生物学会年会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] 新規血管内皮細胞マーカーRobo4のin vivo発現制御機構解析2008
- Author(s)
  岡田欣晃、金恩京、北山美絵、舟橋伸昭、矢野喜一郎、William Aird、土井健史
- Organizer
  第81回日本生化学会大会第31回日本分子生物学会年会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20790064
[Presentation] 新規MRI腫瘍造影剤を目指したPEG化金磁性ナノ粒子の創製2008
- Author(s)
  小島拓記、亀井数正、向洋平、森田将史、犬伏俊郎、清野智史、山本孝夫、吉岡靖雄、岡田直貴、中川晋作
- Organizer
  ファーマ・バイオフォーラム2008
- Place of Presentation
  東京
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 血管内皮細胞と非血管内皮細胞におけるROBO4プロモーターのDNAメチル化状態の相違2008
- Author(s)
  舟橋伸昭、成瀬啓樹、加納義浩、Zhixia Jiang、岡田欣晃、土井健史
- Organizer
  第81回日本生化学会大会第31回日本分子生物学会年会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 家族性血小板減少症(FPD)に見られるRUNX1変異体を血小板系列特異的に発現するES細胞株の樹立2008
- Author(s)
  渡邊美穂, 北山美絵, 原敏郎, 米倉正哲, 登治謙, 山崎大典, William Aird, 北島健二, 仲野徹, 岡田欣晃, 土井健史
- Organizer
  Biochemistry and Molecular Biology 2008
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19390022
[Presentation] Difference of the methylation pattern of the Robo 4 promoter between endothelial cell and non-endothelial cell2008
- Author(s)
  Yoshiaki Okada, Nobuaki Funahashi, Yoshihiro Kano, Hiroki Naruse, Zhixia Jiang, Enjing Jin, Kiichiro Yano, William Aird, Takefumi Doi
- Organizer
  The 6^<th> Korea Japan Joint Symposium on Vascular Biology and The 16th Annual Meeting of the Japan Vascular Biology and Medicine Organization JOINT MEETING
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 金磁性ナノ粒子が可能とする新規遺伝子導入法2008
- Author(s)
  小島拓記、吉川友章、亀井数正、清野智史、山本孝夫、吉岡靖雄、岡田直貴、向洋平、中川晋作
- Organizer
  遺伝子・デリバリー研究会第8回夏季セミナー
- Place of Presentation
  神戸
- Year and Date
  2008-08-08
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 血管内皮細胞に特異的に発現するRobo4の発現制御機構の解析2007
- Author(s)
  岡田欣晃
- Organizer
  Pharmaco-Hematologyシンポジウム
- Place of Presentation
  金沢(金沢エクセルホテル東急)
- Year and Date
  2007-06-07
- Data Source
  KAKENHI-PROJECT-19890117
[Presentation] 3kbのヒトRobo4プロモーターは血管内皮細胞特異的遺伝子発現を制御する2007
- Author(s)
  岡田欣晃
- Organizer
  第30回分子生物学会年会・生化学会大会合同大会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19890117
[Presentation] Robo4 遺伝子の組織特異的な発現はDNA メチル化により制御される　 ―血管内皮細胞特異的な遺伝子発現が生み出されるメカニズムとは―
- Author(s)
  岡田　欣晃
- Organizer
  第62 回日本薬学会近畿支部総会・大会
- Place of Presentation
  武庫川女子大学薬学部（兵庫県）
- Invited
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation]
- Author(s)
  岡田欣晃、金恩京、北山美絵、舟橋伸昭
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 血管内皮細胞特異的遺伝子発現の制御メカニズム解析
- Author(s)
  岡田　欣晃
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Invited
- Data Source
  KAKENHI-PROJECT-23659040
[Presentation] 血管内皮細胞特異的レセプターRobo4の発現制御メカニズムの解析
- Author(s)
  岡田欣晃
- Organizer
  第14回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  日本薬学会長井記念ホール(東京)
- Invited
- Data Source
  KAKENHI-PROJECT-25670056
[Presentation] DNAメチル化サイトへの点変異導入はRobo4プロモーターの組織特異性を失わせる
- Author(s)
  岡田　欣晃
- Organizer
  第６回日本エピジェネティクス研究会年会
- Place of Presentation
  学術総合センター（東京都）
- Data Source
  KAKENHI-PROJECT-23659040

1. DOI Takefumi (00211409)

# of Collaborated Projects: 4 results

# of Collaborated Products: 52 results
2. MUKAI Yohei (60444501)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
3. FUJIO Yasushi (20359839)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 樋野展正 (90469916)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. 櫻井文教 (70370939)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 小山正平 (80767559)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. NAKANO Toru (00172370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. SEINO Satoshi (90432517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
9. MORITA Masahito (30381594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. HATAZAWA Jun (70198745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAGAWA Shinsaku (70207728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
12. YAMAMOTO Takao (00174798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
13. INUBUSHI Toshiro (20213142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
14. KANAI Yasukazu (80467555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OBIKA Satoshi (80243252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KURODA Etsushi (10299604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Suzuki Ryo (90384784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
18. 青枝大貴 (10324344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 工藤信樹 (30271638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. 立花雅史 (80513449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 高山和雄 (10759509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KONDOH masuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. TAKEDA hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. Aird William

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
25. TAKASHIMA Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 橘敬祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 石本憲司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 国安弘基

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
29. 永浜政博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 澤田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 民谷繁幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 舟橋伸昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKADA Yoshiaki 岡田 欣晃

Okada Yoshiaki 岡田 欣晃

Research Projects

Research Products

Co-Researchers

血管バリアに着目する新しい視点での重症感染症の病態・後遺症発症機構の解明と制御Principal Investigator

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血管を経由する新発想での臓器の脱線維化技術の開発Principal Investigator

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Development of anti-inflammatory drugs targeting vascular permeabilityPrincipal Investigator

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Development of novel treatment for fibrotic diseases using direct reprogramming technologyPrincipal Investigator

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Development of novel cancer therapy based on promotion of tumor infiltrating lymphocyte by the immunomodulation with ultrasound technology

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A novel technology for regulating blood brain barrierPrincipal Investigator

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Novel anti-sepsis strategy targeting the endothelial cell-specific receptor Robo4Principal Investigator

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A novel anti-inflammatory strategy by targeting endothelial cell-specific receptor, Robo4Principal Investigator

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Regulation mechanisms involved in tissue-specific gene expression

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DNA methylation and endothelial cell-specific gene expressionPrincipal Investigator

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Construction of antibody-based molecular imaging techniques to analyze a development of tumor angiogenesis.

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The mechanism for endothelial cell-specific gene expression through the Robo4 promoter.Principal Investigator

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Transcription factors regulating normal and pathological platelet differentiation

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OKADA Yoshiaki 岡田欣晃

Okada Yoshiaki 岡田欣晃