MIZUGAKI Michinao 水柿道直

… Alternative Names

水柿通直

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Researcher Number	60004595
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2006: Tohoku Pharmaceutical University, Clinical Pharmaceutics, Professor, 薬学部, 特任教授 2005: 東北薬科大学, 薬学部, 教授 2002: Tohoku Pharmaceutical University, Professor, 薬学部, 教授 1997 – 2001: Tohoku University, Hospital, Professor, 医学部・附属病院, 教授 1996 – 1997: 東北大学, 医学部, 教授 … More 1996: 東北大学, 医学部附属病院, 教授 1995: Tohoku University Hospital, Phamaceatical Sciences, Professor, 医学部附属病院・薬剤部, 教授 1993 – 1995: Tohoku University School of Medicine, Department of Pharmacy, Professor, 医学部・附属病院, 教授 1994: 東北大学, 医学部附属病院, 教授 1993: 東北大学医学部附属病院, 薬剤部, 教授 1990 – 1992: 東北大学, 医学部附属病院, 教授 1991: 東北大学, 附属病院, 教授 1988 – 1989: Tohoku University Hospital, 医学部付属病院, 教授 1988: 東北大学, 医学部・付属病院薬剤部, 教授 1987: 東北大学, 医学部, 教授 1987: 東北大学, 医学部・薬剤部, 教授 1987: 東北大学, 医学部附属病院薬剤部, 教授 1986 – 1987: 東北大学, 医学部附属病院, 教授 1986: 東北大, 医学部, 教授 Less
Review Section/Research Field	Principal Investigator Radiation science / Medical pharmacy / 応用薬理学・医療系薬学 / Psychiatric science Except Principal Investigator 応用薬理学・医療系薬学 / Cerebral neurosurgery / Bioorganic chemistry / Circulatory organs internal medicine / Respiratory organ internal medicine
Keywords	Principal Investigator エイコサペンタエン酸 / MS / GC / Denaturing HPLC / SNP / CYP2D6 / 体内動態 / モニタリング / シュードウリジン / 1-メチルアデノシン … More / 修飾ヌクレオシド / プロスタサイクリン / PGI_3 / プロスタグランジン / regional distribution in brain / ^<11>C-methamphetamine tissue distribution / ^<11>C-imipramine / syhthesis of ^<11>C-labelled drug / 【^(11)C】標識メタンフェタミン / 【^(11)C】標識イミプラミン / レセプター / 脳内分布 / 体内分布 / 11C標識メタンフェタミン / 11C標識イミプラミン / ポジトロン標識薬剤の合成 / Pharmacogenetics / Genetic polymorphism / ファルマコジェネティクス / 遺伝子多型 / LTB_4 / 11beta-PGF_<2alpha> / LC-MS / leukotriene (LT) / 8-isoprostane / cyclooxygenase (COX) / thromboxane / prostaglandin / リポキシゲナーゼ / イムノアッセイ / 測定法 / 血小板活性化因子 / 病態 / 炎症 / トロンボキサン / シクロオキシゲナーゼ / ロイコトリエン / sensitization / biodistribution / addiction / positron / drug / cocaine / 逆耐性 / 中毒 / ポジトロン / 麻薬 / コカイン / 腫瘍マーカー / 予後判定 / 診断 / 固型腫瘍 / 阻害ELISA / DELTA^<17>-2,3-dinor-6-keto PGF_<1α> / 3型PG / 糖尿病 / Δ^<17>-6-keto-PGF_<1α> / TXB_3 / △ ^<17>ー6ーketoーPGF_<1a> / △^<17>-6keto-PGF_<1α> / モノクロ-ナル抗体 / GC@SIM … More Except Principal Investigator GC-MS / GC / MS / モノクローナル抗体 / PET / ELISA / BDMS / PFB / ECNICIMS / SIM / トロンボキサン / プロスタサイクリン / ファージディスプレイ / エイコサペンタエン酸 / inositol phospholipid / 脂質代謝 / 可逆性 / 虚血脳 / ブレインスライス / シナプトゾーム / 〔^3H〕-inositol / 脳虚血 / イノシトールリン脂質 / anesthesia / imaging / EphA5 / Histamine / sensitization / methamphetamine / 受容体 / サル / ヒト / ガングリオシド / DNAメチル化 / MAP / 脳 / ドパミン / 覚醒剤精神病 / 覚醒剤 / 麻酔 / 画像解析 / EphA5受容体 / ヒスタミン / 逆耐性 / メタンフェタミン / olefin metathesis / synthesis / gene / antigen / hapten / antibody / ciguatoxin / 免疫 / コンジュゲート / 海産ポリエーテル / 抗シガトキシン抗体 / シガテラ / 人工抗原 / オレフィンメタセシス / 合成 / 遺伝子配列 / 抗原 / ハプテン / 抗体 / シガトキシン / Rotaviruses / Combinatorial libraries / Human antibodies / Phage display system / ファージディスプレイシステム / ロタウイルス / コンビナトリアルライブラリー / ヒト型抗体 / glucuronide conjugate / 19HETE / 20HETE / PFB-tert-BDMS誘導体 / 19-HETE / 20-HETE / グルクロン酸抱合 / 19 HETE / 20 HETE / biodistribution / 11-dehydro-TXB3 / 11-dehydro-TXB2 / thromboxane / prostacycline / prostaglandin / 3型PG / 阻害ELISA / 6,15-diketo-13,14-dihydro-PGF_<1α> / 11-dehydro-TXB_3 / 糖尿病 / 3型プロスタグランジン / GC-SIM / Measurement / Inflammation / Toxemia of pregnancy / Hypertension / 2, 3-dinor-6-keto-prostaglandin F_1alpha / 11-dehydro-thromboxane B_2 / Thromboxane A_2 / Prostacyclin / 6,15-diketo-13,14 dihydro PGF_1α / 2,3-dinor 6-keto PGF_1α / EIA法 / RIA法 / 6,15-diketo-13,14dehydro PGF_1α / 2,3-dinor-b-keto PGF_1α / 11-dehydro-TXB_2 / プロスタサイクリン(PGI_2) / トロンボキサン(TXA_2) / 炎症 / 妊娠中毒症 / 高血圧 / 測定法 / 2,3-ジノル-6-ケト-PGF1α / 11-デヒドロ-トロンボキサンB2 / 老年期痴呆 / 脳萎縮 / 血管性痴呆 / アルツハイマー病 / 神経伝達物質 / irritant受容体 / C-fiber受容体 / 気管支平滑筋 / 交感神経 / VIP / 即時裂アレルギー反応 / 刺激受容体 / カプサイシン / Cー線継続末 / 非アドレナリン作動性抑制神経 / CDRペプチド / シュードウリジン / マウスモノクローナル抗体 / モノクロ-ナル抗体 / Δ^<17>-6-keto-PGF^<1d> / プロスタグランジン Less

Research Projects
(22 results)
Co-Researchers
(36 People)

Analysis of genetic polymorphisms in human drug-metabolizing enzyme genes and functions of enzymatic proteinsPrincipal Investigator
- Principal Investigator
  
  MIZUGAKI Michinao
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku Pharmaceutical University
Investigation of mechanism of stimulant-induced psychosis -Imaging study by PET -Principal Investigator
- Principal Investigator
  
  HISHINUMA Takanori, 水柿道直
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  TOHOKU UNIVERSITY
A Study on Designed Hapten Aimed at Anti-ciguatoxin Monoclonal Antibody
- Principal Investigator
  
  HIRAMA Masahiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Tohoku University
抗体のCDR領域に由来する機能性ペプチド分子の作製とがん治療への応用
- Principal Investigator
  
  ITOH Kunihiko
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Akita University
Preparation and Clinical application of Human Monoclonal Antibodies using Phage Display System.
- Principal Investigator
  
  ITOH Kunihiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Akita University
尿中トメチルアデノシンとシュードウリジンの固形腫瘍の予後判定への応用Principal Investigator
- Principal Investigator
  
  水柿道直
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Arachibonate cascade and physiologicalPrincipal Investigator
- Principal Investigator
  
  MIZUGAKI Michinao
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
尿中1-メチルアデノシンとシュードウリジンの固形腫瘍の予後判定への応用Principal Investigator
- Principal Investigator
  
  水柿道直
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Development of HETE Analysis by means of mass Spectrometry
- Principal Investigator
  
  OHYAMA Yoshiharu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
エイコサペンタエン酸誘導体の構造と栄養学的意義との関連性の検討Principal Investigator
- Principal Investigator
  
  水柿道直
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Development of microdetermination of 3-series prostanoid and the study of the physiological significance in diseases
- Principal Investigator
  
  HISHINUMA Takanori
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  TOHOKU UNIVERSITY
エイコサペンタエン酸誘導体の構造と栄養学的意義との関連性の検討Principal Investigator
- Principal Investigator
  
  水柿道直
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
3型プロスタノイドの超微量定量を目的としたモノクローナル抗体の作製
- Principal Investigator
  
  菱沼隆則
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
Standardization and problems to measure prostanoids in the biological fluid.
- Principal Investigator
  
  ABE Keishi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  TOHOKU UNIVERSITY
The study of the addiction using positron-labeled cocainePrincipal Investigator
- Principal Investigator
  
  MIZUGAKI Michinao
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Tohoku University
エイコサペンタエン酸誘導体の構造と生物活性との相関(栄養学的意義の再検討)Principal Investigator
- Principal Investigator
  
  水柿道直
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
エイコサペンタエン酸誘導体の構造と生物活性との相関(栄養学的意義の再検討)Principal Investigator
- Principal Investigator
  
  水柿道直
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
エイコサペンタエン酸誘導体の構造と生物活性との相関(栄養学的意義の再検討)Principal Investigator
- Principal Investigator
  
  水柿道直
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
老人(老年期)痴呆の画像解析ーPET・MR-CT(MRI)・X-CTによる定量的計測を中心にー
- Principal Investigator
  
  MATSUZAWA Taiju
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Institution
  Tohoku University
Inositol phospholipid metabolism in cerebral ischemia
- Principal Investigator
  
  KATAKURA Ryuichi, 今泉茂樹
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  TOHOKU UNIVERSITY
未知の気道拡張性神経活性物質の検出および同定・合成に関する研究
- Principal Investigator
  
  井上洋西
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Synthesis and biodistribution of ^<11>C-imipramine and ^<11>C-methamphetaminePrincipal Investigator
- Principal Investigator
  
  MIZUGAKI Michinao
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  TOHOKU UNIVERSITY

1. HISHINUMA Takanori (20199003)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. OHYAMA Yoshiharu (30233290)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. EDO Kiyoto (40125505)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 石橋正兀

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YAMAMOTO Syuzo (50025607)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MUROTA Seiitsu (50072989)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OUTI Kazuo (20006357)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ITOH Kunihiko (90221770)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SUZUKI Toshio (20108559)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. MATSUZAWA Taiju (10006108)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. SATO Mitsumoto (70033321)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. ABE Keishi (60004777)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KATORI Makoto (50050365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. KATAKURA Ryuichi (70152676)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. SHIMIZU Takao (80127092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. OMATA Ken (50194634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HIRAMA Masahiro (30165203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OGURI Hiroki (80311546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TOMIOKA Yoshihisa (00282062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YANAI Kazuhiko (50192787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ITO Masatoshi (00125501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. IDO Tatsuo (80134063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. NUMACHI Yotaro (00261636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. HIRATSUKA Masahiro (50282140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KONNO Yumiko (90364413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. SASAKI Takamitsu (20382674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. ENDO Masao (40004668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. MOTOMIYA Masakichi (20006092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 井上洋西 (40133962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 飛田渉 (10142944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 無江季次 (40004882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 石井慶造 (00134065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 武田俊平 (00006115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 小暮久也 (20133936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 今泉茂樹 (30160039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 石田名香雄

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIZUGAKI Michinao 水柿 道直

水柿 通直

Research Projects

Co-Researchers

Analysis of genetic polymorphisms in human drug-metabolizing enzyme genes and functions of enzymatic proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of mechanism of stimulant-induced psychosis -Imaging study by PET -Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

尿中トメチルアデノシンとシュードウリジンの固形腫瘍の予後判定への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Arachibonate cascade and physiologicalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

尿中1-メチルアデノシンとシュードウリジンの固形腫瘍の予後判定への応用Principal Investigator

Principal Investigator

Project Period (FY)

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Principal Investigator

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エイコサペンタエン酸誘導体の構造と栄養学的意義との関連性の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

エイコサペンタエン酸誘導体の構造と栄養学的意義との関連性の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

The study of the addiction using positron-labeled cocainePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

MIZUGAKI Michinao 水柿道直

水柿通直