Fujii Nobutaka 藤井信孝

… Alternative Names

FUJII Nobutaka 藤井信孝

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Researcher Number	60109014
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Affiliation (Current)	2025: 京都大学, 薬学研究科, 名誉教授
Affiliation (based on the past Project Information) *help	2015 – 2018: 京都大学, 薬学研究科, 名誉教授 2017: 京都大学, 薬学部, 名誉教授 2017: 京都大学, 薬学部, 教授 2011 – 2014: 京都大学, 薬学研究科(研究院), 教授 1997 – 2008: Kyoto University, Graduated School of Pharmaceutical Sciences, Professor, 薬学研究科, 教授 … More 2006: 京都大学, 薬学部, 教授 2001: Graduate School of Pharmaceutical Sciences, Kyoto University, Professor, 薬学研究科(研究院), 教授 1999 – 2001: 京都大学, 大学院・薬学研究科, 教授 1989 – 1996: Faculty of Pharmaceutical Sciences, Kyoto Univ. Professor., 薬学部, 教授 1987 – 1988: Faculty of Pharmaceutical Sciences, Kyot University, 薬学部, 助教授 1986: 京大, 薬学部, 助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Drug development chemistry / 医薬分子機能学 / Chemical pharmacy / Bioorganic chemistry Except Principal Investigator Chemical pharmacy / Digestive surgery / Drug development chemistry / General surgery / Biomedical engineering/Biomaterial science and engineering … More / Pathological medical chemistry / Biological Sciences / Physical pharmacy / 膠原病・アレルギー・感染症内科学 / Bioorganic chemistry Less
Keywords	Principal Investigator CXCR4 / ケモカイン / 癌 / T140 / 構造活性相関 / GPR54 / 環状ペプチド / CXCR4拮抗剤 / ジスルフィド形成反応 / 創薬テンプレート … More / gp41 / 有機銅試薬 / T22 / HIV第二受容体拮抗剤 / GPCR / G-protein coupled receptor / Constitutively Active Receptor Technology / HIVプロテアーゼ阻害剤 / エイズ / 立体配座固定 / ペプチドイソスター / Bombesin Antagonist / 抗腫瘍活性 / ボンベシンアンタゴニスト / polyphemusin / tachyplesin / FC131 / CXCR4ケモカイン受容体 / 複素環 / キナーゼ / コンビナトリアル合成 / 薬剤耐性 / SDF-1 / 膜融合阻害剤 / SARS Corona Virus / 小細胞肺癌 / 膵臓癌 / 乳癌 / ケモカイン受容体 / HIV-cell融合阻害剤 / de novo設計 / 基質遷移状態模倣型酵素阻害剤 / aza-Payne転位反応 / Plasmepsin II / マラリア / 合理的分子設計 / ペプチド / 1 M trimethylsilyl trifluoromethanesulfonate / cancer cell growth / mitogenic factor / human transforming growth factor-<alpha> / タリウム(【III】)酸化 / トリメチルシリルトリフラート / 癌診断 / 【N^(ih)】-benzyloxymethyl histidine / ヒト腫瘍細胞増殖因子α / トリフルオロメタンスルホン酸銀塩 / 1Mトリメチルシリルトリフルオロメタンスルホネート / 腫瘍細胞増殖 / 成長因子 / ヒト腫瘍増殖因子-α / chemical proteomics / Seven transmembrane protein / Intein-splicing system / Bioluminescece Resonance Energy Transfer / 非ペプチド化 / GPR-54 / 光感受性保護基 / Cysteine-ligation / 7TMGPCR / ケミカルプロテオミクス / 7回膜貫通型受容体 / chemical ligation / CXCR4 antagonist / Peptide Chemistry / peptide-isosteres / drug discovery / genome science / ユニバーサル創薬テンプレート / αVβ3-integrin / 7TM-GPCR / プロテオーム / ゲノム / リウマチ / Germinal Center / HIV感染 / 7回膜貫通型レセプター / 蛋白質化学 / ゲノム情報 / 7回膜貫通型GPCR / Chemical Ligation / ペプチド化学 / 創薬研究 / ゲノム科学 / de novo design / HIV-cell fusion inhibitors / low molecular weight CXCR4 antagonists / T-cell line-tropic HIV / chemokine receptor / anti-HIV agents / 有用金属試薬 / エイス / 逆転写酵素阻害 / T140立体構造 / 二価官能性抗HIV剤 / 多剤耐性克服型抗HIV剤 / spring8 / SC34EK / gp41-標的型HIV-Cell膜融合阻害剤 / T140-CXCR4ドッキング解析 / 機能性CXCR4変異体 / ホモロジーモデリング / 環状ペンタペプチドライブラリー / T細胞指向性HIV-1 / HIV侵入阻害剤 / CXCR4アンタゴニスト / de novo分子設計 / 低分子化 / 多剤耐性HIV / T細胞指向性HIV / CXCR4ケモカインレセプター / HIV進入阻害剤 / Alkene-type tipeptide isostere / Organocopper Reagent / HIV-protease / β-Secretase / aza-Payne Rearrangement / Substrate Transition State Mimic / Aspartyl Protease / Stereoselective Synthesis / ケモカインアンタゴニスト / 遷移金属触媒 / 基質遷移状態ミミック構造 / 非天然型アミノ酸誘導体 / (E)-Alkcnc型dipcptidcisostcrc / オレフィンメタセシス閉環反応 / 多剤耐性HIV型プロテアーゼ / β-secretase / グローバル配座固定 / Ru-触媒メタセシス閉環反応 / ペプチドリード医薬品 / 有機亜鉛-銅複合試薬 / アルツハイマー型痴呆症 / αVβ3インテグリン拮抗剤剤 / ゲノム情報集約型ライブラリー / アルケン型ジペプチドイソスター / HIVプロテアーゼ / β-セクレターゼ / aza-Payne転位 / 基質遷移状態模倣型阻害剤 / アスパルチルプロテアーゼ / 立体的選択的合成反応 / Allylpalladium Complex / Organopalladium Compound / Vinylaziridine / Aziridinylenoate / Alkene Isostere / SN2-type Ring-Opening / Organocopper Compound / トリプトフアン・イソスター / トリプトファン・イソスター / アリルパラジウム錯体 / 有機パラジウム化合物 / ビニルアジリジン / アジリジニル・エノエイト / アルケンイソスター / SN2型開環反応 / ボンベシン・アンタゴニスト / 有機銅化合物 / Stereocontrolled Synthetic Route / Anti-Cancer Activity / Inhibition of Amylase Release / (E)-Alkene Dipeptide Isosters / Palladium(0) / Activated Aziridinyl Enoates / Organocopper Reagents / 膵癌細胞増殖抑制 / 遷移金属触媒による異性化反応 / (E)-アルケン型ジペプチドイソスター / 立体特異的1,3-不斉転移 / キラルプール / 立体制御合成プロセス / アミラーゼ分泌抑制 / (E)-アルケンジペプチドイソスター / 0価パラジウム / 活性化アジリジンエノエ-ト / solution-phase synthesis / HCI / AgOTf-DMSO / T cell / beta-sheet / anti-HIV activity / β-sheet / NMR / DMSO / AgOTf / HCl / AgOTf‐DMSO / 液相合成 / T細胞 / β‐sheet / 抗HIV活性 / Nonhydrolyzable Phosophopeptide / Tau-protein / Trk-receptor / Disulfide-bond Formation / Chemoselective Purification / Neurotrophin / Alzheimer Disase / Senile Dementia / Arg-vasopressin(4-9) / アフィニテイークロマト / Biotin化試薬 / 老人性痴呆症 / ジスルフィド形成 / ジメチルスルホキシド / 化学選択的固定化 / 二価官能性試薬 / フラグメント縮合 / NGF / アルツハイマー / NGF合成促進因子 / 非水解性リン酸化ペプチド / Tau蛋白質 / Trk受容体 / 化学選択的精製法 / 神経栄養因子 / アルツハイマー型痴呆 / 老人性痴呆 / Silver Trifluoromethanesulphonate / S-Deprotecting Reagent / Big Endothelin / Endothelin / Caイオンチャンネル / システインのSH保護基 / 血管収縮作用 / トリメチルシリルブロマイド / トリフルオロメタンスルホン酸銀 / Sー脱保護試薬 / ビッグエンドセリン / エンドセリン / トリメチルシリルトリフルオロメタンスルホネート(TMSOTf) / Sー保護システインスルホキシド / カルシトニン遺伝子関連ペプチド(cGRP) / 膵蛋白放出活性 / トリメチルシリルトリフルオロメタンスルホネート / 選択的硫酸エステル化 / ヒトコレシストキニン全合成 / 天然有機化合物 / 鏡像体 / 生物活性化合物 / アッセイ / スクリーニング / 化合物ライブラリー / 天然物 / 複素環骨格構築反応 / ドラッグライク / 分子設計 / キネシンモータータンパク / jaspine B / スフィンゴシンキナーゼ / プロテインキナーゼCK2 / ホモロジーモデル / CXCR7ケモカイン受容体 / キネシン / KSP / CK2 / CXCR7 / 固相反応 / インドール / インドリン / キノリン / イソキノリン / 多成分反応 / ケミカルバイオロジー / ドラッグ指向性 / 化合物バンク / kisspeptin / Kisspeptin / Eg5 / ALL / 立体配座固定創薬テンプレート / ストローマ細胞依存性薬物耐性 / 癌転移メカニズム / 癌の化学療法剤 / CXCR4-ケモカイン受容体 / X-EE-XX-KK配列 / Nelfinavir / 比較ゲノミクス / defensin / SARS CoVゲノム / Bioinformatics / XEEXXKK概念 / HIV膜融合阻害剤 / インフルエンザウイルス / 猫エイズ / VERO-E6細胞 / SARSCoV / I-型ウイルス-宿主細胞膜融合 / 新興・再興ウイルス / 骨髄ストローマ細胞依存性薬剤耐性 / 癌転移抑制剤 / 慢性リンパ性B-Cell白血病 / メラノーマ / 血液癌 / 癌転移 / リポソーム / 脂質膜 / HIV / タンパク質合成 / 脂質二重膜 / ペプチドチオエステル / 膜タンパク質 / 受容体 / MAGI細胞 / T20 / 化学合成ワクチン / 多剤耐性株 / 3-ヘリックスバンドル構造 / Spring 8 / MAGI assay / SC34 / X-線解析 / 6-helical bundle / HIV-cell膜融合阻害剤 / Ru-触媒オレフィンメタセシス / Pd(0) / ケモカインレセプター / T-細胞指向性HIV / マラリアワクチン / Duffy-結合様ドメイン / ChondroitinsulfateA / Plasmodium falciparum … More Except Principal Investigator スクリーニング / p16 / Avidin-biotin / 不斉合成 / DDS / ペプチド合成 / 免疫抑制剤 / ハイブリッド型人工膵 / 膵再生 / EGF / BIRドメイン / カスパーゼ / SH2ドメイン / 医薬品探索 / キラル化合物 / ペプチド / 天然物 / KSP / 末梢神経障害 / 微小管阻害薬 / 乳癌 / kinesin spindle protein / デポ製剤 / 生分解材料 / 注射ゲル / 生体材料 / エラスチン / 徐放 / ペプチド製剤 / 創剤 / 注射ゲル製剤 / 人工エラスチン / 高分子型プロドラッグ / ポリペプチド / 薬物送達 / 抗HIVペプチド / 抗HIV / 低分子化合物スクリーニング / 化合物スクリーニング / TBP-2 / イノベーション / アルファアレスチン / 癌抑制 / 創薬 / ケミカルバイオロジー / 低分子化合物 / インスリン抵抗性 / 癌 / 糖尿病 / Txnip / Insulin / CGRP / Open-chain unsymmetrical cystine peptide / Sulfoxide-directed disulfide bond forming reaction / Thallium (III) oxidation / リラキシンの全合成 / 非対称シスチン含有ペプチドの合成法インシュリンの改良合成 / ニワトリカルシトニン遺伝子関連ペプチド / 非対称シスチンペプチド / リラキシン / インシュリン / カルシトニン遺伝子関連ペプチド / Sー保護システインスルホキシド / 非対称ジスルフィルド形成反応 / Esperamicin / Opioid receptor / Peptide synthesis / Chiral synthesis / Modified oligonucleotide / P-450 model / Retinoid / Chiral 5-deazaflavin / 生物活性物質 / 生物有機化学 / レセプター / 作用機序の解明 / 機能性分子の合成 / 蛋白質 / 核酸 / ヒトパンクレオスタチン / 5-デアザフラビン / ペプチヂ合成 / 修飾オリゴフクレオチド / P-450モデル / 面不斉5-デアザフラビン / エスペラミシン / オピオイド受容体 / レチノイド / オリゴヌクレオチド / Pー450モデル / 5ーデアザフラビン / Pancreatic cancer / integrin αV β3 / Signal transduction / Bcl-X gene / Apoptosis / 受容体 / 遺伝子 / 膵癌治療 / DcR3 / 膵癌 / インテグリンαvβ3 / シグナル伝達 / Bcl-X遺伝子 / アポトーシス / Reverse transcriptase inhibitor / Neutralizing antibody / Vpr transgenic mouse / Membrane fusion inhibitor / CXCR4 inhibitor / Drug resistance / CCR5 inhibitor / Protease inhibitor / u-CRM1 / rev / フィットネス / 転写制御 / tat / CTL / 抗ウイルス剤 / 発症予防ワクチン / ケモカインレセプター阻害剤 / hu-PBL-SCIDマウス / 遺伝子発現制御 / トランスジェニックマウス / CXCR4拮抗剤 / T140 / HIV-1 / 逆転写酵素阻害剤 / 中和抗体 / Vprトランスジェニックマウス / 膜融合阻害剤 / CXCR4阻害剤 / 薬剤耐性 / CCR5阻害剤 / プロテアーゼ阻害剤 / Affinity purification / Defensin / Protegrin / Self-defense peptide / Disulfide bond / Solid-phase synthesis / アフィニティークロマト / デフェンシン / プロテグリン / 生体防御ペプチド / ジスルフィド結合 / 固相合成 / Ample supply of useful enzymes / Development of chiral synthon / Modification of amino acid / Organometalic Chenistry / Asymmetric Synthesis / Biologically active natural products / Protein Phosphayase Inhibitor / Tautomycin,A / アレニルスルホニウム / 甘味成分 / 海洋性天然物 / 生物活性天然物 / アミノ酸修飾 / 生理活性微量天然物合成 / 有用酵素の量的供給 / 不斉合成素子の開発 / アミノ酸装飾 / 有機金属化合物の利用 / 生理活発微量天然物合成 / Orientation / Conformation / Membrane permeability / Lipid membrane / Tachyplesin / Magainin / Trichopolyn / Hypelcin / タチプレシン / 配向 / コンホメ-ション / 膜透過性 / 脂質膜 / タキプレシン / マガイニン / トリコポリン / ヒペルシン / Transplantation / Hybrid islet pancreas with MRPT / Isolation of islet from adult pit pancreas / FK506 and cyclosporine / Post-gastrectomy gallstone / Endothelin & pancreas / GIP & splanchnic circulation / EGF & Pancreatic regeneration / 成熟ブタラ氏島 / ハイブリッド人工膵 / 肝血流 / 膵外分泌 / 成熟ブタ膵ラ氏島 / GIP / 胃切除後胆石 / 成熟ブタ分離ラ氏島 / 移植 / ポリビニ-ルアルコ-ル / 感染症 / 好中球 / 抗菌薬 / パラジウム触媒 / 還元的アルキル化 / 有機銅試薬 / ボンベシン / GRP / (E)-アルケン型ジペプチドイソスター / ペプチドリード医薬品 / GRP拮抗剤 / アルケン / ペプチドイソスター / 重点領域 / 分子設計 / 構造活性相関 / ペプチド三次構造 / 生体内信号 / ペプチド科学 / 生体機能性ペプチド / バッグタイプ人工膵 / MRPT / 分離ラ島 / シオニン / アッセイ / 急性膵炎 / 異種移植 / ラ島移植 / 膵炎 / エンドセリン / プタキロサイド / ポルフィリン / エナペラミシン / ブレオマイシン / ダイネミシン / 抗腫瘍性抗生物質 / DNA切断 / DNA認識 Less

Development of Novel Drug Discovery Technologies for Target Proteins with Elusive Molecular BasisPrincipal Investigator
- Principal Investigator
  
  Fujii Nobutaka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
Development of anti HIV peptide applying multifunctional polypeptide
- Principal Investigator
  
  Nakashima Hideki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  St. Marianna University School of Medicine
Potential new chemotherapy for breast cancer therapy with a novel KSP inhibitor
- Principal Investigator
  
  Ohta Yuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St. Marianna University School of Medicine
Develoment of a screening platform using mirror-image proteins and their application to drug discovery
- Principal Investigator
  
  Shinya Oishi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
Elucidation of the molecular mechanism of insulin resistance by investigating TBP-2/Txnip and chemical biology
- Principal Investigator
  
  MASUTANI Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Development and application of a novel screening technolgy toward effective uses of chemical libraryPrincipal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
Practical medicinal chemistry on the basis of protein chemistry, computational science and synthetic technologies for a variety of heterocyclesPrincipal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
多重標的創薬概念に基づくがん化学療法の新機軸Principal Investigator
- Principal Investigator
  
  大石真也, 藤井信孝
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
GPCR周辺の細胞外環境解明のためのケミカルプローブの創出と応用Principal Investigator
- Principal Investigator
  
  大石真也, 藤井信孝
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
癌転移・骨髄依存薬物耐性の動的超分子機構解明のケミカルプローブ創出と創薬展開Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
有機化学を基盤にしたGPCR細胞外環境のケミカルバイオロジー研究Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ドラッグ指向性化合物バンクの構築と創薬展開Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
CXCR4を分子標的とした癌転移およびストローマ細胞依存性薬物耐性の克服Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
好中球を利用した抗菌薬を感染病巣に到達させる特異的DDSの開発
- Principal Investigator
  
  笹田昌孝
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kyoto University
Evolution of Drug Discovery Targeting for G-protein Coupled ReceptorsPrincipal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
CXCR4を標的とする癌転移抑制剤の開発Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
生物情報科学を活用した新興ウイルス性感染症に対する化学療法剤の実践的開発戦略研究Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
腫瘍転移抑制剤を指向した実用的CXCR4アンタゴニストの開発研究Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ケミカルレセプトームの開発と応用Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
Genome/Proteome-lead Drug Discovery Based on Peptide/Protein ChemistryPrincipal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
HIV-Cell融合遷移状態を標的とした化学合成ワクチンの開発Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
DEVELOPMENT OF NOVEL ANTI -HIV AGENTS BASED ON HIGHLY' SELECTIVE CHEMOKINE RECEPTOR CXCR$ ANTAGONISTSPrincipal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY
マラリア原虫の増殖機構をターゲットとする新規マラリア治療薬の開発研究Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
低分子CXCR4アンタゴニストT22を基盤構造とした抗エイズ治療薬の開発研究Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
(E)-アルケンペプチドイソスターを探索子とする高活性GRP拮抗剤の創製
- Principal Investigator
  
  大高章
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
Basic Research for AIDS control A03 ; Prevention and control of AIDS
- Principal Investigator
  
  MATSUSHITA Shuzo
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  KUMAMOTO UNIVERSITY
Molecular cancer therapy based on the pathological analysis of the pancreatic cancer
- Principal Investigator
  
  HOSOTANI Ryo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
Studies on Practical Strategy for Peptide-lead Drug Discovery and DevelopmentPrincipal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY
(E)-アルケンペプチドイソスターを探索子とする高活性GRP拮抗剤の創製
- Principal Investigator
  
  OTAKA Akira
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Development of highly efficient, selective, and practical synthetic method of pseudo-peptides possessing anti-tumour activity.Principal Investigator
- Principal Investigator
  
  FUJII Nobutaka, 井深俊郎
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Synthesis of Peptide Isosteres with Strong Bombesin Antagonist Activity and Its Development to Anti-Cancer AgentsPrincipal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY
機能性ペプチドの分子設計における新展開
- Principal Investigator
  
  宗像英輔
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  University of Tsukuba
Synthetic Studies for Ample Supply of Biologically Active Natural Products
- Principal Investigator
  
  IRIE Hiroshi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Ngasaki University
Synthetic Study on Neurotrophins and Its Application for Development of Diagnostic Immunoassay Method for Senile DementiaPrincipal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  KYOTO UNIVERSITY
Development of efficient synthetic methods for peptides and syntheses of self-defense peptides possessing anti-virus activity
- Principal Investigator
  
  OTAKA Akira
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Studies on the elucidantion of action mechanisms of tachyplesin analogs as anti-HIV peptidesPrincipal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY
消化管ホルモンを介する臓器相関
- Principal Investigator
  
  INOUE Kazutomo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
生物活性分子による核酸の精密構造認識と機能発現
- Principal Investigator
  
  杉浦幸雄
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Effect of Gastrointestinal Hormones on Organ Interrelationship
- Principal Investigator
  
  INOUE Kazutomo, TOBE Takayoshi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Interactions of antibiotic peptides with lipid membranes
- Principal Investigator
  
  MIYAJIMA Koichiro
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Synthetic Studies on Endothelin and Its Related Peptides Using a New S-Derotecting ReagentPrincipal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
新しいジスルフィド形成反応を用いるカルシトニン遺伝子関連ペプチドの合成研究Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
選択的硫酸エステル化法によるヒトコレシストキニンの全合成Principal Investigator
- Principal Investigator
  
  藤井信孝
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyoto University
New Frontier in Bioorganic Chemistry Research
- Principal Investigator
  
  YONEDA Fumio
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
Exploitation of a New Unsymmetrical Disulfide-Bonding Reaction and Its Application to the Synthesis of Cystine-Conatining Peptides
- Principal Investigator
  
  YAJIMA Haruaki
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
Synthetic Studies on Human Transforming Growth Factor(hTGF)-<alpha>Principal Investigator
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University

[Book] ケミカルバイオロジー研究を基盤にした抗癌剤の創出：KSP阻害剤の創出2012
- Author(s)
  竹内智起、大石真也、藤井信孝
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23390025
[Book] インシリコ創薬科学2008
- Author(s)
  大石真也、藤井信孝、他
- Total Pages
  210
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-20015021
[Book] インシリコ創薬科学2008
- Author(s)
  大石真也、藤井信孝、他
- Total Pages
  210
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-20057011
[Book] Screening and characterization of cyclic pentapeptide CXCR4 antagonists/inverse agonists using a pheromone responsive reporter gene in Saccharomyces cerevisiae: utility of G plotein coupled receptor constitutively active mutants2007
- Author(s)
  Fujii N., et. al.
- Publisher
  Birkhaeuser
- Data Source
  KAKENHI-PROJECT-18659027
[Book] プロテオミクスを基盤とするケミカルバイオロジー-情報から制御へ2006
- Author(s)
  藤井信孝, 他
- Total Pages
  6
- Publisher
  オーム社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Book] 細胞工学(特集)飛躍するケミカルバイオロジー:科学から生命現象を明らかに(分担執筆)2005
- Author(s)
  藤井信孝, 大高章, 玉村啓和
- Total Pages
  6
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-17209004
[Book] Chemokine Roles in Immunoregulation and Disease(ed by P.M.Murphy & R.Horuk)2004
- Author(s)
  H.Zhang, N.Fujii, S.C.Peiper, et al.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Head-to-Tail Macrocyclization of Cysteine-Free Peptides Using an o-Aminoanilide Linker2018
- Author(s)
  T. Ohara, M. Kaneda, T. Saito, N. Fujii, H. Ohno, S. Oishi
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 28 Issue: 8 Pages: 1283-1286
- DOI
  10.1016/j.bmcl.2018.03.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KT0061, KAKENHI-PROJECT-15H04654, KAKENHI-PROJECT-15J05499
[Journal Article] Synthesis of Jaspine B Regioisomers through Palladium-Catalyzed Stereoselective Tetrahydrofuran Formation: Insight into the Ligand Recognition of Sphingosine Kinases2018
- Author(s)
  Miyagawa, S. Inuki, M. Honda, S. Nakamura, I. Nakanishi, N. Fujii, S. Oishi, H. Ohno
- Journal Title
  
  Tetrahdron
  
  Volume: 74 Issue: 15 Pages: 1802-1809
- DOI
  10.1016/j.tet.2018.02.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KT0061, KAKENHI-PROJECT-15H04654, KAKENHI-PUBLICLY-18H04408, KAKENHI-PROJECT-17H03971
[Journal Article] Structure-Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3)2018
- Author(s)
  Sekiguchi Haruka、Kuroyanagi Tomoko、Rhainds David、Kobayashi Kazuya、Kobayashi Yuka、Ohno Hiroaki、Heveker Nikolaus、Akaji Kenichi、Fujii Nobutaka、Oishi Shinya
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 61 Issue: 8 Pages: 3745-3751
- DOI
  10.1021/acs.jmedchem.8b00336
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04654, KAKENHI-PROJECT-16H05104
[Journal Article] Identification of Selective Inhibitors of Sphingosine Kinases 1 and 2 through a Structure-Activity Relationship Study of 4-epi-Jaspine B2017
- Author(s)
  H. Ohno, M. Honda, N. Hamada, J. Miyagaki, A. Iwata, K. Otsuki, T. Maruyama, S. Nakamura, I. Nakanishi, S. Inuki, N. Fujii, S. Oishi
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 25 Issue: 12 Pages: 3046-3052
- DOI
  10.1016/j.bmc.2017.03.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24689001, KAKENHI-PROJECT-15KT0061, KAKENHI-PROJECT-15H04654, KAKENHI-PROJECT-17H03971
[Journal Article] Synthesis of Grb2 SH2 domain proteins for mirror-image screening systems.2017
- Author(s)
  Noguchi T, Ishiba H, Honda K, Kondoh Y, Osada H, Ohno H, Fujii N, Oishi S.
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 28 Issue: 2 Pages: 609-619
- DOI
  10.1021/acs.bioconjchem.6b00692
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14J07738, KAKENHI-PROJECT-26350976, KAKENHI-PROJECT-15H04653
[Journal Article] Synthesis of the Src SH2 domain and its application in bioassays for mirror-image screening2017
- Author(s)
  Shu Keitou、Noguchi Taro、Honda Kaori、Kondoh Yasumitsu、Osada Hiroyuki、Ohno Hiroaki、Fujii Nobutaka、Oishi Shinya
- Journal Title
  
  RSC Advances
  
  Volume: 7 Issue: 61 Pages: 38725-38732
- DOI
  10.1039/c7ra07445j
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04653
[Journal Article] Investigation of the inhibitory mechanism of apomorphine against MDM2-p53 interaction.2017
- Author(s)
  Ishiba H, Noguchi T, Shu K, Ohno H, Honda K, Kondoh Y, Osada H, Fujii N, Oishi S
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 印刷中 Issue: 11 Pages: 2571-2574
- DOI
  10.1016/j.bmcl.2017.03.082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26350976, KAKENHI-PROJECT-15H04653
[Journal Article] A Novel KSP Inhibitor, KPYB10602, Induces Mitotic Arrest and Cell Death in Breast Cancer Cells2016
- Author(s)
  Kojima-Tsuchiya Seiko, Ohta Yuki, Takenaga Mitsuko, Niimi Jun, Watanabe Daiki, Tsunoda Satoshi, Ootaki Masanori, Oishi Shinya, Fujii Nobutaka, Matsumoto Naoki, Tsugawa Koichiro
- Journal Title
  
  Journal of St.Marianna University
  
  Volume: 7 Pages: 105-116
- NAID
  130005251535
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10074
[Journal Article] Development of novel NK3 receptor antagonists with reduced environmental impact2016
- Author(s)
  Yamamoto Koki、Okazaki Shiho、Ohno Hiroaki、Matsuda Fuko、Ohkura Satoshi、Maeda Kei-ichiro、Fujii Nobutaka、Oishi Shinya
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 24 Issue: 16 Pages: 3494-3500
- DOI
  10.1016/j.bmc.2016.05.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04654
[Journal Article] Screening of a virtual mirror-image library of natural products2016
- Author(s)
  T. Noguchi, S. Oishi, K. Honda, Y. Kondoh, T. Saito, H. Ohno, H. Osada, N. Fujii
- Journal Title
  
  Chem. Comm.
  
  Volume: 52 Issue: 49 Pages: 7653-7656
- DOI
  10.1039/c6cc03114e
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04653, KAKENHI-PROJECT-15H04654, KAKENHI-PROJECT-14J07738, KAKENHI-PROJECT-26350976
[Journal Article] Total Synthesis of (+)-Conolidine by the Gold(I)-Catalyzed Cascade Cyclization of a Conjugated Enyne2016
- Author(s)
  S. Naoe, Y. Yoshida, S. Oishi, N. Fujii, H. Ohno
- Journal Title
  
  J. Org. Chem.
  
  Volume: 81 Issue: 13 Pages: 5690-5698
- DOI
  10.1021/acs.joc.6b00720
- NAID
  120006634624
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24689001, KAKENHI-PROJECT-15KT0061, KAKENHI-PROJECT-15H04654
[Journal Article] Formal Total Synthesis of (±)-Strictamine Based on a Gold-Catalyzed Cyclization2016
- Author(s)
  D. Nishiyama, A. Ohara, H. Chiba, H. Kumagai, S. Oishi, N. Fujii, H. Ohno
- Journal Title
  
  Org. Lett.
  
  Volume: 18 Issue: 7 Pages: 1670-1673
- DOI
  10.1021/acs.orglett.6b00536
- NAID
  120006634625
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15KT0061, KAKENHI-PROJECT-24689001, KAKENHI-PROJECT-15H04654
[Journal Article] Structure-Activity Relationship Study of 4-(Thiazol-5-yl)benzoic Acid Derivatives as Potent Protein Kinase CK2 Inhibitors2016
- Author(s)
  H. Ohno, D. Minamiguchi, S. Nakamura, K. Shu, S. Okazaki, M. Honda, R. Misu, H. Moriwaki, S. Nakanishi, S. Oishi, T. Kinoshita, I. Nakanishi, N. Fujii
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 24 Issue: 5 Pages: 1136-1141
- DOI
  10.1016/j.bmc.2016.01.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KT0061, KAKENHI-PROJECT-24689001, KAKENHI-PROJECT-15H04654
[Journal Article] Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors2016
- Author(s)
  Alam, M., Kuwata, T., Shimura, K., Yokoyama, M., Ramirez Valdez, K. P., Tanaka, K., Maruta, Y., Oishi, S., Fujii, N., Sato, H., Matsuoka M. and Matsushita S.
- Journal Title
  
  Retrovirology
  
  Volume: 13 Issue: 1 Pages: 70-70
- DOI
  10.1186/s12977-016-0304-7
- NAID
  120005973385
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430091, KAKENHI-PROJECT-16K08824, KAKENHI-PROJECT-15H04654, KAKENHI-PROJECT-15H04870
[Journal Article] CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent manner2016
- Author(s)
  Abdelouahab Hadjer、Zhang Yanyan、Wittner Monika、Oishi Shinya、Fujii Nobutaka、Besancenot Rodolphe、Plo Isabelle、Ribrag Vincent、Solary Eric、Vainchenker William、Barosi Giovanni、Louache Fawzia
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 33 Pages: 54082-54095
- DOI
  10.18632/oncotarget.10789
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04654
[Journal Article] A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo.2016
- Author(s)
  Watanabe M, Hashimoto K, Abe Y, Kodama EN, Nabika R, Oishi S, Ohara S, Sato M,Kawasaki Y, Fujii N, Hosoya M.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 9 Pages: e0162823-e0162823
- DOI
  10.1371/journal.pone.0162823
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05346, KAKENHI-PROJECT-15H04654
[Journal Article] Novel 3,4,7-Substituted Benzofuran Derivatives Having Binding Affinity to κ-Opioid Receptor2016
- Author(s)
  D. Nishiyama, Y. Sakai, H. Sekiguchi, H. Chiba, R. Misu, S. Oishi, N. Fujii, H. Ohno
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 64 Issue: 7 Pages: 996-1003
- DOI
  10.1248/cpb.c16-00302
- NAID
  130005160050
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24689001, KAKENHI-PROJECT-15KT0061, KAKENHI-PROJECT-15H04654
[Journal Article] Formal [4+2] reaction between 1,3-diynes and pyrroles: gold(I)-catalyzed indole synthesis by double hydroarylation2015
- Author(s)
  Matsuda Y, Naoe S, Oishi S, Fujii N, Ohno H.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 21 Issue: 4 Pages: 1463-1467
- DOI
  10.1002/chem.201405903
- NAID
  120005613671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24689001
[Journal Article] Potential new chemotherapy strategy for human ovarian carcinoma with a novel KSP inhibitor2015
- Author(s)
  Takenaga, M., Yamamoto, Y., Takeuchi T., Ohta, Y., Tokura, Y., Hamaguchi, A., Asai, D., Nakashima, H., Oishi, S., and Fujii, N.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 463 Issue: 3 Pages: 222-228
- DOI
  10.1016/j.bbrc.2015.05.029
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K01319, KAKENHI-PROJECT-26460050, KAKENHI-PROJECT-25462618
[Journal Article] Structure-activity relationship study on senktide for development of novel potent neurokinin-3 receptor selective agonists.2015
- Author(s)
  Misu R, Yamamoto K, Yamada A, Noguchi T, Ohno H, Yamamura T, Okamura H, Matsuda F, Ohkura S, Oishi S, Fujii N.
- Journal Title
  
  MedChemCommun
  
  Volume: 6 Issue: 3 Pages: 469-476
- DOI
  10.1039/c4md00514g
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J06309, KAKENHI-PROJECT-14J07738, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23689007, KAKENHI-PROJECT-24380154
[Journal Article] Synthesis of Fused Carbazoles by Gold-Catalyzed Tricyclization of Conjugated Diynes via Rearrangement of an N-Propargyl Group2015
- Author(s)
  M. Taguchi, Y. Tokimizu, S. Oishi, N. Fujii, H. Ohno
- Journal Title
  
  Org. Lett.
  
  Volume: 17 Issue: 24 Pages: 6250-6253
- DOI
  10.1021/acs.orglett.5b03254
- NAID
  120006634626
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15KT0061, KAKENHI-PROJECT-24689001, KAKENHI-PROJECT-15H04654
[Journal Article] Dual gold catalysis: a novel synthesis of bicyclic and tricyclic pyrroles from N-propargyl ynamides2015
- Author(s)
  Tokimizu Y, Wieteck M, Rudolph M, Oishi S, Fujii N, Hashmi ASK, Ohno H.
- Journal Title
  
  Org. Lett.
  
  Volume: 17 Issue: 3 Pages: 604-607
- DOI
  10.1021/ol503623m
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24689001
[Journal Article] Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation.2014
- Author(s)
  Misu R, Oishi S, Yamada A, Yamamura T, Matsuda F, Yamamoto K, Noguchi T, Ohno H, Okamura H, Ohkura S, Fujii N.
- Journal Title
  
  J. Med. Chem.
  
  Volume: 57 Issue: 20 Pages: 8646-8651
- DOI
  10.1021/jm500771w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06309, KAKENHI-PROJECT-14J07738, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23689007, KAKENHI-PROJECT-24380154
[Journal Article] Gold-catalyzed cascade cyclization of (azido)ynamides: an efficient strategy for the construction of lndoloquinolines2014
- Author(s)
  Tokimizu Y, Oishi S Fujii N, Ohno H.
- Journal Title
  
  Org. Lett.
  
  Volume: 16 Issue: 11 Pages: 3138-3141
- DOI
  10.1021/ol5012604
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24689001
[Journal Article] A radiogallium-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for tumor imaging2014
- Author(s)
  Sano K, Masuda R, Hisada H, Oishi S, Shimokawa K, Ono M, Fujii N, Saji H, Mukai T.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Issue: 5 Pages: 1386-1388
- DOI
  10.1016/j.bmcl.2014.01.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23689007
[Journal Article] Optimization of diaryl amine derivatives as kinesin spindle protein inhibitors2014
- Author(s)
  Takeuchi T, Oishi S, Kaneda M, Misu R, Ohno H, Sawada J, Asai A, Nakamura S, Nakanishi I, Fujii N.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22 Issue: 12 Pages: 3171-3179
- DOI
  10.1016/j.bmc.2014.04.008
- NAID
  120005466732
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390025
[Journal Article] Synthesis of fused tetracyclic spiroindoles via palladium-catalysed cascade cyclisation2014
- Author(s)
  Akira Iwata, Shinsuke Inuki, Shinya Oishi, Nobutaka Fujii and Hiroaki Ohno
- Journal Title
  
  Chemical Communications
  
  Volume: 50 Issue: 3 Pages: 298-300
- DOI
  10.1039/c3cc46511j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05601, KAKENHI-PROJECT-23390025, KAKENHI-PUBLICLY-24106720, KAKENHI-PROJECT-24689001
[Journal Article] Synthesis of IB-01212 by multiple N-methylations of peptide bonds.2014
- Author(s)
  Nabika R, Oishi S, Misu R, Ohno H, Fujii N.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22 Issue: 21 Pages: 6156-6162
- DOI
  10.1016/j.bmc.2014.08.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06309, KAKENHI-PROJECT-14J07872, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24659004
[Journal Article] Design and synthesis of fluorescent probes for GPR54.2014
- Author(s)
  Kaneda M, Misu R, Ohno H, Hirasawa A, Ieda N, Uenoyama Y, Tsukamura H, Maeda K, Oishi S, Fujii N.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22 Issue: 13 Pages: 3325-3330
- DOI
  10.1016/j.bmc.2014.04.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06309, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23689007, KAKENHI-PROJECT-26252046
[Journal Article] Synthesis and biological evaluation of the [D-MeAlall]-epimer of coibamide A.2014
- Author(s)
  Nabika R, Suyama TL, Hau AM, Misu R, Ohno H, Ishmael JE, McPhail KL, Oishi S, Fujii N.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 2 Pages: 302-306
- DOI
  10.1016/j.bmcl.2014.11.044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06309, KAKENHI-PROJECT-14J07872, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24659004
[Journal Article] Kinesin spindle protein inhibitors with diaryl amine scaffolds: crystal packing analysis for improved aqueous solubility2014
- Author(s)
  Takeuchi T, Oishi S, Kaneda M, Ohno H, Nakamura S, Nakanishi I, Yamane M, Sawada J, Asai A, Fujii N.
- Journal Title
  
  ACS Med. Chem. Lett.
  
  Volume: 5 Issue: 5 Pages: 566-571
- DOI
  10.1021/ml500016j
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390025
[Journal Article] Characterization of the receptor binding residues of kisspeptins by positional scanning using peptide photoaffinity probes2013
- Author(s)
  Misu R, Oishi S, Setsuda S, Noguchi T, Kaneda M, Ohno H, Evans B, Navenot JM, Peiper SC, Fujii N.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Issue: 9 Pages: 2628-2631
- DOI
  10.1016/j.bmcl.2013.02.098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06309, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23689007
[Journal Article] Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 4041822013
- Author(s)
  Tsukasa Mizuhara, Shinya Oishi, Hiroaki Ohno, Kazuya Shimura, Masao Matsuoka, Nobutaka Fujii
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 21 Issue: 7 Pages: 2079-2087
- DOI
  10.1016/j.bmc.2013.01.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J01895, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24791021
[Journal Article] Convergent Synthesis of (-)-Quinocarcin Based on the Combination of Sonogashira Coupling and Gold (I)-Catalyzed 6-endo-dig Hydroamination2013
- Author(s)
  Hiroaki Chiba, Yuki Sakai, Ayako Ohara, Shinya Oishi, Nobutaka Fujii, Hiroaki Ohno
- Journal Title
  
  Chemistry A European Journal
  
  Volume: (in press) Issue: 27 Pages: 8875-8883
- DOI
  10.1002/chem.201300687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J01905, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24689001, KAKENHI-PUBLICLY-24106720
[Journal Article] Diversity-oriented synthesis of pyrazolo[4,3-b]indoles by gold-catalysed three-component annulation: application to the development of a new class of CK2 inhibitors2013
- Author(s)
  Hou Z, Oishi S, Suzuki Y, Kure T, Nakanishi I., Hirasawa A, Tsujimoto G, Ohno H, Fujii N.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 11 Issue: 20 Pages: 3288-3296
- DOI
  10.1039/c3ob40223a
- NAID
  120005474525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23659038, KAKENHI-PROJECT-24689001, KAKENHI-PUBLICLY-24106720
[Journal Article] Structure-activity relationship study of phenylpyrazole derivatives as a novel class of anti-HIV agents2013
- Author(s)
  Mizuhara T, Kato T, Hirai A, Kurihara H, Shimada Y, Taniguchi M, Maeta M, Togami H, Shimura K, Matsuoka M, Okazaki S, Takeuchi T, Ohno H, Oishi S, Fujii N.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Issue: 16 Pages: 4557-4561
- DOI
  10.1016/j.bmcl.2013.06.026
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24791021
[Journal Article] Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: identification of novel peptidic inhibitors.2013
- Author(s)
  Noguchi T, Oishi S, Honda K, Kondoh Y, Saito T, Kubo T, Kaneda M, Ohno H, Osada H, Fujii N
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 23 Issue: 13 Pages: 3802-3805
- DOI
  10.1016/j.bmcl.2013.04.094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510287, KAKENHI-PROJECT-24659046
[Journal Article] Synthesis of pachastrissamine (jaspine B) and its derivatives by the late-stage introduction of the C-2 alkyl side-chains using olefin cross metathesis2013
- Author(s)
  Yoshimitsu Y, Miyagaki J, Oishi S, Fujii N, Ohno H.
- Journal Title
  
  Tetrahedron
  
  Volume: 69 Issue: 21 Pages: 4211-4220
- DOI
  10.1016/j.tet.2013.03.091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24659046, KAKENHI-PROJECT-24689001, KAKENHI-PUBLICLY-24106720
[Journal Article] An optimized method of G-protein coupled receptor homology modeling: its application to the discovery of novel CXCR7 ligands2013
- Author(s)
  Yoshikawa Y, Oishi S, Kubo T, Tanahara N, Fujii N, Furuya T.
- Journal Title
  
  J. Med. Chem.
  
  Volume: 56 Issue: 11 Pages: 4236-4251
- DOI
  10.1021/jm400307y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23689007
[Journal Article] Structure-Activity Relationship Study of a CXC Chemokine Receptor Type 4 Antagonist, FC131, Using a Series of Alkene Dipeptide Isosteres2012
- Author(s)
  Kobayashi K., et al
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: (in press) Issue: 6 Pages: 2746-2757
- DOI
  10.1021/jm2016914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02083, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23570192, KAKENHI-PROJECT-23689007
[Journal Article] Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4)2012
- Author(s)
  Oishi S, Fujii N.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 10 Issue: 30 Pages: 5720-5731
- DOI
  10.1039/c2ob25107h
- NAID
  120005243444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025
[Journal Article] Paradoxical downregulation of CXC chemokine receptor 4 induced by polyphemusin II-derived antagonists.2012
- Author(s)
  Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Yano Y, Matsuzaki K, Navenot J, Peiper S, Fujii N.
- Journal Title
  
  Bioconjug. Chem.
  
  Volume: 23 Issue: 6 Pages: 1259-1265
- DOI
  10.1021/bc300084h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23659038, KAKENHI-PROJECT-23689007
[Journal Article] Structure-based Design of Novel Potent CK2 Inhibitors with Phenyl-azole Scaffolds.2012
- Author(s)
  Z. Hou, I. Nakanishi, T. Kinoshita, Y. Takei, M. Yasue, R. Misu, Y. Suzuki, S. Nakamura, T. Kure, H. Ohno, K. Murata, K. Kitaura, A. Hirasawa, G. Tsujimoto, S. Oishi, N. Fujii.
- Journal Title
  
  J. Med. Chem.
  
  Volume: 55 Issue: 6 Pages: 2899-2903
- DOI
  10.1021/jm2015167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590110, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23659038
[Journal Article] Efficient Synthesis of Aminomethylated Azaindoles and Corresponding Pyrrole-Fused Derivatives by Copper-Catalyzed Domino Multicomponent Coupling and Cyclization2012
- Author(s)
  Hou, Z., Ohno, H., et al
- Journal Title
  
  Tetrahedron
  
  Volume: 68 Issue: 6 Pages: 1695-1703
- DOI
  10.1016/j.tet.2011.12.059
- NAID
  120003874274
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22106521, KAKENHI-PROJECT-22590005, KAKENHI-PROJECT-23390025
[Journal Article] Development and application of fluorescent SDF-1 derivatives2012
- Author(s)
  Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Kodama E, Matsuoka M, Fujii N.
- Journal Title
  
  Future Med. Chem.
  
  Volume: 4 Issue: 7 Pages: 837-844
- DOI
  10.4155/fmc.12.31
- NAID
  120005285488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23590636, KAKENHI-PROJECT-23659038, KAKENHI-PROJECT-23689007
[Journal Article] Concise synthesis and anti-HIV activity of pyrimido[1,2-c][1,3]benzothiazin-6-imines and related tricyclic heterocycles.2012
- Author(s)
  Mizuhara T, Oishi S, Ohno H, Shimura K, Matsuoka M, Fujii N.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 10 Issue: 33 Pages: 6792-6802
- DOI
  10.1039/c2ob25904d
- NAID
  120005302103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24791021
[Journal Article] Structure-activity relationship study of pyrimido[1, 2-c][1,3]benzothiazin-6-imine derivatives for potent anti-HIV agents.2012
- Author(s)
  Tsukasa Mizuhara, Shinya Oishi, Hiroaki Ohno, Kazuya Shimura, Masao Matsuoka, Nobutaka Fujii
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 20 Issue: 21 Pages: 6334-6441
- DOI
  10.1016/j.bmc.2012.08.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J01895, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-24791021
[Journal Article] Non-invasive longitudinal imaging of tumor progression using an 111Indium labeled CXCR4 peptide antagonist.2012
- Author(s)
  Buckle T, Van den Berg NS, Kuil J, Bunschoten A, Oldenburg J, Borowsky AD, Wesseling J, Masada R, Oishi S, Fujii N, Van Leeuwen FB.
- Journal Title
  
  Am. J. Nucl. Med. Mol. Imaging,
  
  Volume: 2 Pages: 99-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025
[Journal Article] Design and synthesis of novel class of CK2 inhibitors : application of copper- and gold-catalysed cascade reactions for fused nitrogen heterocycles.2012
- Author(s)
  Suzuki Y, Oishi S, Takei Y, Yasue M, Misu R, Naoe S, Hou Z, Kure T, Nakanishi I, Ohno H, Hirasawa A, Tsujimoto G, Fujii N.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 10 Issue: 25 Pages: 4907-4915
- DOI
  10.1039/c2ob25298h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06309, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23659038
[Journal Article] Molecular Modeling Study of Cyclic Pentapeptide CXCR4 Antagonists : New Intsight into CXCR4-FC131 Interactions2012
- Author(s)
  Kobayashi K., Yoshikawa Y., et al
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 22 Issue: 6 Pages: 2146-2150
- DOI
  10.1016/j.bmcl.2012.01.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02083, KAKENHI-PROJECT-23390025
[Journal Article] Gold-Catalyzed Three-Component Annulation : Efficient Synthesis of Highly Functionalized Dihydropyrazoles from Alkynes, Hydrazines, and Aldehydes or Ketones2012
- Author(s)
  Suzuki, Y., Ohno, H., et al
- Journal Title
  
  Org.Lett.
  
  Volume: 14 Issue: 1 Pages: 326-329
- DOI
  10.1021/ol203072u
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22106521, KAKENHI-PROJECT-22590005, KAKENHI-PROJECT-23390025
[Journal Article] Pachastrissamine (Jaspine B) and Its Stereoisomers Inhibit Sphingosine Kinases and Atypical Protein Kinase C2011
- Author(s)
  Yoshimitsu Y.Oishi S.miyagaki J.Inuki S.Ohno H.Fujii N.
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 19 Issue: 18 Pages: 5402-5408
- DOI
  10.1016/j.bmc.2011.07.061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02576, KAKENHI-PROJECT-23390025
[Journal Article] "Structure-activity relationships of carboline and carbazole derivatives as a novel class of ATP-competitive kinesin spindle protein inhibitors"2011
- Author(s)
  Takeuchi T, Oishi S, Watanabe T, Ohno H, Sawada J, Matsuno K,Asai A, Asada N, Kitaura K, Fujii N.
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 54巻 Issue: 13 Pages: 4839-4846
- DOI
  10.1021/jm200448n
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590067, KAKENHI-PROJECT-23390025
[Journal Article] Fluorescent imaging of high grade bladder cancer using a specific antagonist for chemokine receptor CXCR42010
- Author(s)
  Nishizawa K, Oishi S, Fujii N, et al.
- Journal Title
  
  Int.J.Cancer
  
  Volume: 127 Pages: 1180-1187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Fluorescent imaging of high grade bladder cancer using a specific antagonist for chemokine receptor CXCR42010
- Author(s)
  Nishizawa K, Oishi S, Fujii N, et al.
- Journal Title
  
  Int.J.Cancer
  
  Volume: 127 Pages: 1180-1187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres2010
- Author(s)
  Narumi T, Ohno H, Oishi S, Fujii N, et al.
- Journal Title
  
  Org.Biomol.Chem.
  
  Volume: 8 Pages: 616-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres2010
- Author(s)
  Narumi T, Ohno H, Oishi S, Fujii N, et al.
- Journal Title
  
  Org.Biomol.Chem.
  
  Volume: 8 Pages: 616-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors2009
- Author(s)
  Hyunsuk S., Oishi S., Fujii N., et.al.
- Journal Title
  
  Semin. Cancer Biol 19
  
  Pages: 123-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] SDF-1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair2009
- Author(s)
  Kitaori T., Oishi S., Fujii N., et.al.
- Journal Title
  
  Arthritis Rheum 60
  
  Pages: 813-823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Amino acid-based synthesis of trifluoromethylalkene dipeptide isosteres by alcohol-assisted nucleophilic trifluoromethylation and organozinc-ccopper-mediated SN2' alkylation2009
- Author(s)
  Kobayashi K, Oishi S, Ohno H, Fujii N, et al.
- Journal Title
  
  J.Org.Chem.
  
  Volume: 74 Pages: 4626-4629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Prognostic value of metastin expression in human pancreatic cancer2009
- Author(s)
  Nagai K, Oishi S, Fujii N, et al.
- Journal Title
  
  J.Exp.Clin.Cancer Res.
  
  Volume: 28 Pages: 9-9
- NAID
  120004770245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclicpentapeptide scaffold : the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids2009
- Author(s)
  Tanaka T, Oishi S, Fujii N, et al.
- Journal Title
  
  Org.Biomol.Chem
  
  Volume: 7 Pages: 3805-3809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Prognostic value of metastin expression in human pancreatic cancer2009
- Author(s)
  Nagai K, Oishi S, Fujii N, et al.
- Journal Title
  
  J.Exp.Clin.Cancer Res.
  
  Volume: 28 Pages: 9-9
- NAID
  120004770245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Targeted disruption of the CXCL12/CXCR4 axis inhibits osteolysis in a murine model of mveloma-associated bone loss2009
- Author(s)
  Diamond P., Fujii N., et.al.
- Journal Title
  
  J. Bone Miner
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Amino acid-based synthesis of trifluoromethylalkene dipeptide isosteres by alcoholassisted nucleophilic trifluoromethylation and organozinc-ccopper-mediated SN2' alkylation2009
- Author(s)
  Kobayashi K, Oishi S, Ohno H, Fujii N, et al.
- Journal Title
  
  J.Org.Chem.
  
  Volume: 74 Pages: 4626-4629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] SDF-1/CXCR4 signaling is critical for the recruitment of mesenchvmal stem cells to the fracture site during skeletal repair2009
- Author(s)
  Kitaori T., Oishi S., Fujii N., et.al.
- Journal Title
  
  Arthritis Rheum 60
  
  Pages: 813-823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold : the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids2009
- Author(s)
  Tanaka T, Oishi S, Fujii N, et al.
- Journal Title
  
  Org.Biomol.Chem.
  
  Volume: 7 Pages: 3805-3809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Targeted disruption of the CXCL12/CXCR4 axis inhibits osteolysis in a murine model of myeloma-associated bone loss2009
- Author(s)
  Diamond P., Fujii N., et.al.
- Journal Title
  
  J. Bone Miner
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists2009
- Author(s)
  Evans BJ, Oishi S, Fujii N, et al.
- Journal Title
  
  Methods Enzymol.
  
  Volume: 460 Pages: 399-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists2009
- Author(s)
  Evans BJ, Oishi S, Fujii N, et al.
- Journal Title
  
  Methods Enzymol.
  
  Volume: 460 Pages: 399-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors2009
- Author(s)
  Hyunsuk S., Oishi S., Fujii N., et.al.
- Journal Title
  
  Semin. Cancer Biol 19
  
  Pages: 123-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Clinical significance of plasma metastin level in pancreatic cancer patients2009
- Author(s)
  Katagiri F, Oishi S, Fujii N, et al.
- Journal Title
  
  Oncol.Rep.
  
  Volume: 21 Pages: 815-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Clinical significance of plasma metastin level in pancreatic cancer patients2009
- Author(s)
  Katagiri F, Oishi S, Fujii N, et al.
- Journal Title
  
  Oncol.Rep.
  
  Volume: 21 Pages: 815-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Development of peptide-targeted lipoplexes to CXCR4-expressing rat glioma cells and rat proliferating endothelial cells2008
- Author(s)
  Driessen W.H., Fujii N., et.al.
- Journal Title
  
  Mol. Ther 16
  
  Pages: 516-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Stromal-derived factor 1 signalling regulates radial and tangential migration in the developing cerebral cortex2008
- Author(s)
  Liapi A., Fujii N., et.al.
- Journal Title
  
  Dev. Neurosci 30
  
  Pages: 117-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Structure-activity relationship study of CXCR4 antagonists bearing the cyclic pentapeptide scaffold : identification of the new pharmacophore2008
- Author(s)
  Tanaka T., Fujii N., et.al.
- Journal Title
  
  Org. Biomol. Chem 6
  
  Pages: 4374-4377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Direct construction of bicyclic heterocycles by palladium-catalyzed domino cyclization of propargyl bromides.2008
- Author(s)
  Ohno H., Okano A., Kosaka S., Tsukamoto K., Ohata M., Ishihara K., Maeda H., Tanaka T., Fujii N.
- Journal Title
  
  Org. Lett. 10
  
  Pages: 1171-1174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Modulation of network-driven, GABA-mediated giant depolarizing potentials by SDF-la in the developing hippocampus2008
- Author(s)
  Kasiyanov A., Fujii N., et.al.
- Journal Title
  
  Dev. Neurosci 30
  
  Pages: 285-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Synthesis of highly functionalized alkene dipeptide isosteres and its application to the structure-activity relationship study on bioactive peptides2008
- Author(s)
  Oishi S., Fujii N., et.al.
- Journal Title
  
  J. Synth. Org. Chem. Jpn 66
  
  Pages: 846-857
- NAID
  10024278609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres by palladium-catalyzed carbonylation of amino acid-derived allylic carbonates.2008
- Author(s)
  Inokuchi E., Narumi T., Niida A., Kobayashi K., Tomita K., Oishi S., Ohno H., Fujii N.
- Journal Title
  
  J. Org. Chem. 73
  
  Pages: 3942-3945
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Modulation of network-driven, GABA-mediated giant depolarizing potentials by SDF-la in the developing hippocampus2008
- Author(s)
  Kasiyanov A., Fujii N., et.al.
- Journal Title
  
  Dev. Neurosci 30
  
  Pages: 285-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] A future perspective on the development of chemokine receptorCXCR4 antagonists2008
- Author(s)
  Tamamura H., Fujii N., et.al.
- Journal Title
  
  Expert Opin. Drug Discov 3
  
  Pages: 1155-1166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Facile synthesis of 3-(aminomethyl)isoquinolines by copper-catalysed domino four-component coupling and cyclisation.2008
- Author(s)
  Ohta Y., Oishi S., Fujii N., Ohno H.
- Journal Title
  
  Chem. Commun. 7
  
  Pages: 835-837
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres by palladium-catalyzed carbonylation of amino acid-derived allylic carbonates2008
- Author(s)
  Fujii N., Ohno H., Oishi, S., et. al.
- Journal Title
  
  J. Org. Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Stromal-derived factor 1 signalling regulates radial and tangential migration in thedeveloping cerebral cortex2008
- Author(s)
  Liapi A., Fujii N., et al
- Journal Title
  
  Dev. Neurosci 30
  
  Pages: 117-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to fmoc-based solid phase synthesis of a cyclic pentapeptide mimetic.2008
- Author(s)
  Narumi T., Tomita K., Inokuchi E., Kobayashi K., Oishi S., Ohno H., Fujii N.
- Journal Title
  
  Tetrahedron 64
  
  Pages: 4332-4346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Blockade of CXCL12/CXCR4 axis ameliorates murine experimentalcolitis2008
- Author(s)
  Mikami S., Fujii N., et.al.
- Journal Title
  
  J. Pharmacol. Exp. Ther 327
  
  Pages: 383-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Design of a novel HIV-1 fusion inhibitor that displays a minimal interface for binding affinity2008
- Author(s)
  Fujii N., Ohno H., Oishi, S., et. al.
- Journal Title
  
  J. Med. Chem. 51
  
  Pages: 388-391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Synthesis of highly functionalized alkene dipeptide isosteres and its application to thestructure-activity relationship study on bioactive peptides2008
- Author(s)
  Oishi S., Fujii N., et.al.
- Journal Title
  
  J. Synth. Org. Chem. Jpn 66
  
  Pages: 846-857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid phase synthesis of a cyclic pentapeptide mimetic2008
- Author(s)
  Narumi T., Oishi S., Fujii N., et.al.
- Journal Title
  
  Tetrahedron 64
  
  Pages: 4332-4346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Palladium-catalyzed sp3 C-H activation of simple alkyl groups: direct preparation of indoline derivatives from N-alkyl-2-bromoanilines2008
- Author(s)
  Fujii N., Ohno H., Oishi, S., et. al.
- Journal Title
  
  Org. Lett. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Identification of novel nonpeptide CXCR4 antagonists by ligand-baseddesian aporoach2008
- Author(s)
  Ueda S., Oishi S., Fujii N., et.al.
- Journal Title
  
  Bioorg. Med. Chem. Lett 18
  
  Pages: 4124-4129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Design of a novel HIV-1fusion inhibitor that displays a minimal interface for binding affinity.2008
- Author(s)
  Oishi S., Ito S., Nishikawa H., Watanabe K., Tanaka M., Ohno H., Izumi K., Sakagami Y., Kodama E., Matsuoka M., Fujii N.
- Journal Title
  
  J. Med. Chem. 51
  
  Pages: 388-391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Potent synergistic anti-HIV effects using combinations of a CCR52008
- Author(s)
  Nakata H., Fujii N., et.al.
- Journal Title
  
  Antimicrob. Agents. Chemother 52
  
  Pages: 2111-2119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Heptad repeat-derived peptides block protease-mediated direct entry from the cell surface of severe acute respiratory syndrome coronavirus but not entry via the endosomal pathway pathway.2008
- Author(s)
  Ujike M., Nishikawa H., Otaka A., Yamamoto N., Yamamoto N., Matsuoka M., Kodama E., Fujii N., Taguchi F.
- Journal Title
  
  J. Virol. 82
  
  Pages: 588-592
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of peptide-targeted lipoplexes to CXCR4-expressing rat glioma cells and rat proliferating, endothelial cells.2008
- Author(s)
  Driessen W. H., Fujii N., Tamamura H., Sullivan S. M.
- Journal Title
  
  Mol. Ther. 16
  
  Pages: 516-524
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres bypalladium-catalyzed carbonylation of amino acid-derived Arlie carbonates2008
- Author(s)
  Inokuchi E., Oishi S., Fujii N., et.al.
- Journal Title
  
  J. Org. Chem 73
  
  Pages: 3942-3945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Blockade of CXCL12/CXCR4 axis ameliorates murine experimental colitis2008
- Author(s)
  Mikami S., Fujii N., et.al.
- Journal Title
  
  J. Pharmacol. Exp. Ther 327
  
  Pages: 383-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Potent synergistic anti-HIV effects using combinations of a CCR52008
- Author(s)
  Nakata H., Fujii N., et.al.
- Journal Title
  
  Antimicrob. Agents. Chemother 52
  
  Pages: 2111-2119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Development of novel GPR54 agonists with resistance to degradation by matrix metalloproteinase2008
- Author(s)
  Tomita K., Oishi S., Fujii N., et.al.
- Journal Title
  
  J. Med. Chem 51
  
  Pages: 7645-7649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Identification of novel nonpeptide CXCR4 antagonists by ligand-based design approach2008
- Author(s)
  Ueda S., Oishi S., Fujii N., et.al.
- Journal Title
  
  Bioorg. Med. Chem. Lett 18
  
  Pages: 4124-4129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres by palladium-catalyzed carbonylation of amino acid-derived allylic carbonates2008
- Author(s)
  Inokuchi E., Oishi S., Fujii N., et.al.
- Journal Title
  
  J. Org. Chem 73
  
  Pages: 3942-3945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and itsapplication to Fmoc-based solid phase synthesis of a cyclic pentapeptide mimetic2008
- Author(s)
  Narumi T., Oishi S., Fujii N., et.al.
- Journal Title
  
  Tetrahedron 64
  
  Pages: 4332-4346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Facile synthesis of 3-(aminomethyl) isoquinolines by copper-catalysed domino four-component coupling and cyclisation2008
- Author(s)
  Fujii N., Ohno H., Oishi, S., et. al.
- Journal Title
  
  Chem. Commun. 7
  
  Pages: 835-837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Direct construction of bicyclic heterocycles by palladium-catalyzed domino cyclization of propargyl bromides2008
- Author(s)
  Fujii N., Ohno H., et. al.
- Journal Title
  
  Org. Lett. 10
  
  Pages: 1171-1174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to fmoc-based solid phase synthesis of a cyclic pentapeptide mimetic2008
- Author(s)
  Fujii N., Ohno H., Oishi, S., et. al.
- Journal Title
  
  Tetrahedron (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Structure-activity relationship study of CXCR4 antagonists bearing the cyclic pentapeptide scaffold : identification of the new pharmacophore2008
- Author(s)
  Tanaka T., Fujii N., et.al.
- Journal Title
  
  Org. Biomol. Chem 6
  
  Pages: 4374-4377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Palladium-catalyzed sp3 C-H activation of simple alkyl groups: direct preparation of indoline derivatives from N-alkyl-2-bromoanilines.2008
- Author(s)
  Watanabe T., Oishi S., Fujii N., Ohno H.
- Journal Title
  
  Org. Lett. 10
  
  Pages: 1759-1762
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of peptide-targeted lipoplexes to CXCR4-expressing rat glioma cells andrat proliferating endothelial cells2008
- Author(s)
  Driessen W.H., Fujii N., et.al.
- Journal Title
  
  Mol. Ther 16
  
  Pages: 516-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] A future perspective on the development of chemokine receptor CXCR4 antagonists2008
- Author(s)
  Tamamura H., Fujii N., et.al.
- Journal Title
  
  Expert Opin. Drug Discov 3
  
  Pages: 1155-1166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015021
[Journal Article] Synthesis and application of fluorescein- and botin-labeled molecular probes for chemokine receptor CXCR4.2008
- Author(s)
  Oishi S., Masuda R., Evans B., Ueda S., Goto Y., Ohno H., Hirasawa A., Tsujimoto G., Wang Z., Peiper S. C., Naito T., Kodama E., Matsuoka M., Fujii N.
- Journal Title
  
  Chem BioChem 9
  
  Pages: 1154-1158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Stromal-derived factor 1 signalling regulates radial and tangential migration in the developing cerebral cortex.2008
- Author(s)
  Liapi A., Pritchett J., Jones O., Fujii N., Parnavelas J. G., Nadarajah B.
- Journal Title
  
  Dev. Neurosci. 30
  
  Pages: 117-131
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of novel GPR54 agonists with resistance to degradation by matrixmetalloproteinase2008
- Author(s)
  Tomita K., Oishi S., Fujii N., et.al.
- Journal Title
  
  J. Med. Chem 51
  
  Pages: 7645-7649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20057011
[Journal Article] Establishment and clinical application of enzyme immunoassays for determination of luteinizing hormone releasing hormone and metastin.2007
- Author(s)
  Katagiri F., Tomita K., Oishi S., Takeyama M., Fujii N.
- Journal Title
  
  J. Pept. Sci. 13
  
  Pages: 422-429
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Direct synthesis of 2-(aminomethyl)indoles through copper(I)-catalyzed domino three-component coupling and cyclization reactions.2007
- Author(s)
  Ohno H., Ohta Y., Oishi S., Fujii N.
- Journal Title
  
  Angew. Chem. Int. Ed. 46
  
  Pages: 2295-2298
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Direct Synthesis of 2-(Aminomethyl)indoles through Copper(I)-Catalyzed Domino Three-Component Coupling and Cyclization Reactions.2007
- Author(s)
  Ohno, H., Oishi, S., Fujii, N.et al.
- Journal Title
  
  Angew. Chem. Int. Ed. Engl. 46・13
  
  Pages: 2295-2298
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Inhibitors of the chemokine receptor CXCE4 : chemotherapy of AIDS, metastatic cancer, leukemia and rheumatoid arthritis.2007
- Author(s)
  Tsutsumi H., Tamamura H., Fujii N.
- Journal Title
  
  Lett. Drug Design Discov. 4
  
  Pages: 20-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Synthesis of (Z)-alkene-containing cis-proline dipeptide mimetics using samarium(II) diiodide (SmI_2)-mediated reduactive alkylation2007
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  Tetrahedron 63・9
  
  Pages: 2000-2008
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] The therapeutic potential of the chemokine receptor CXCR4 antagonists as multi-functional agents.2007
- Author(s)
  Tsutsumi H., Tanaka T., Ohashi N., Masuno H., Tamamura H., Hiramatsu K., Araki T., Ueda S., Oishi S., Fujii N.
- Journal Title
  
  Biopolymers 88
  
  Pages: 279-289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Bromoallenes as allyl dication equivalents in the presence or absence of palladium(O) : direct construction of bicyclic sulfamides containing five-to eight-membered rings by tandem cyclization of bromoallenes.2007
- Author(s)
  Hamaguchu, H., Ohno, H., Fujii, N., Tanaka, T.et al.
- Journal Title
  
  Chem.Eur.J. 13・6
  
  Pages: 1692-1708
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Development of copper-mediated allylation of y-activated-a, B-unsaturated lactam toward peptide mimetic synthesis.2007
- Author(s)
  Sasaki Y., Fujii N., Otaka A.
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 3221-3224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Structureactivity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists : disclosing the importance of side-chain and hackbone2007
- Author(s)
  Ueda S., Oishi S., Wang Z. X., Araki T., Tamamura H., Cluzeau J., Ohno H. Kusano S., Nakashima H., Trent J. O., Peiper S. C., Fujii N.
- Journal Title
  
  J. Med. Chem. 50
  
  Pages: 192-198
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling2007
- Author(s)
  Fujii N., Ohno H., Oishi, S., et. al.
- Journal Title
  
  Chem. Commun. 43
  
  Pages: 4516-4518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Development of copper-mediated allylation of γ-activated-α, β-unsaturated lactam toward peptide mimetic synthesis.2007
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  Tetrahedron Lett. 48・18
  
  Pages: 3221-3224
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of copper-mediated allylation of γ-activated-α,β-unsaturated lactam toward peptide mimetic synthesis.2007
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  Tetrahedron Lett. 48・18
  
  Pages: 3221-3224
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] A Highly Regio- and Stereoselective Formation of Bicyclo[4.2.0]oct-5-ene Derivatives through Thermal Intramolecular [2+2] Cycloaddition2007
- Author(s)
  Ohno, H., Fujii, N., Tanaka, T.
- Journal Title
  
  J.Ore.Chem. (in press)
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Heck-type cyclization of oxime ethers : stereoselective carbon-carbon bond formation with aryl halides to produce heterocyclic oximes.2007
- Author(s)
  Ohno H., Aso A., Kadoh Y., Fujii N., Tanaka T.
- Journal Title
  
  Angew. Chem. Int. Ed. 46
  
  Pages: 6325-6328
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and Gai activation.2007
- Author(s)
  Berchiche Y. A., Chow K. Y., Lagane B., Leduc M., Percherancier Y., Fujii N., Tamamura H., Bachelerie F., Heveker N.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 5111-5115
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists.2007
- Author(s)
  Cluzeau J., Oishi S., Ohno H., Wang Z., Evans B., Peiper S. C., Fujii N.
- Journal Title
  
  Org. Biomol. Chem. 5
  
  Pages: 1915-1923
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of copper-mediated allylation of γ-activated-α,β-unsaturated lactam toward peptide mimetic synthesis.2007
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  Tetrahedron Lett. 48・18
  
  Pages: 3221-3224
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] CXCL12-CXCR4 engagement is required for migration of cutaneous dendritic cells2007
- Author(s)
  Kabashima K., Shiraishi N., Sugita K., Mori T., Onoue A., Kobayashi M., Sakabe J., Yoshiki R., Tamamura H., Fujii N., Inaba K., Tokura Y.
- Journal Title
  
  Am. J. Pathol. 171
  
  Pages: 1249-1257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Versatile use of acid-catalyzed ring-opening of □-aziridinyl-□, □ enoates to stereoselective synthesis of peptidomimetics.2007
- Author(s)
  Tamamura H., Tanaka T., Tsutsumi H., Nemoto K., Mizokami S., Ohashi N., Oishi S., Fujii N.
- Journal Title
  
  Tetrahedron 63
  
  Pages: 9243-9254
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and G(alpha)(i) activation.2007
- Author(s)
  Berchiche, Y.A., Fujii, N., Heveker, N.et al.
- Journal Title
  
  J.Biol.Chem. 282・8
  
  Pages: 5111-5115
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Direct Synthesis of 2-(Aminomethyl)indoles through Copper(I)-Catalyzed Domino Three-Component Coupling and Cyclization Reactions.2007
- Author(s)
  Ohno, H., Fujii, N.et al.
- Journal Title
  
  Angew.Chem.Int.Ed.Engl. 46・13
  
  Pages: 2295-2298
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Development of low molecular weight CXCR4 antagonists by exploratory structural tuning of cyclic tetra- and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis.2007
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  Curr Med Chem 14・1
  
  Pages: 93-102
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Synthesis of (Z)-alkene-containing cis-proline dipeptide mimetics using samarium(II) diiodide (SmI2)-mediated reduactive alkylation2007
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  Tetrahedron 63・9
  
  Pages: 2000-2008
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] A Highly Regio- and Stereoselective Formation of Bicyclo[4.2.0]oct-5-ene Derivatives through Thermal Intramolecular [2 + 2] Cycloaddition of Allenes2007
- Author(s)
  Ohno, H., Fujii, N., Tanaka, T.
- Journal Title
  
  J. Org. Chem. (in press)
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Synthesis of (Z)-alkene-containing cis-proline dipeptide mimetics using samarium(II) diiodide (SmI_2)-mediated reduactive alkylation2007
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  Tetrahedron 63・9
  
  Pages: 2000-2008
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Development of low molecular weignt CXCR4 antagonists by exploratory structural tuning of cyclic tetra- and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis2007
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  Curr Med Chem 14・1
  
  Pages: 93-102
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment.2007
- Author(s)
  Juarez, J., Fujii, N., Bendall, L.J.et al.
- Journal Title
  
  Leukemia (in press)
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Synthesis of (Z)-alkene-containing cis-proline dipeptide mimetics using samarium(II) diiodide (SmI_2)-mediated reduactive alkylation2007
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  Tetrahedron 63・9
  
  Pages: 2000-2008
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres.2007
- Author(s)
  Tomita, K., Oishi, S., Fujii, N.et al.
- Journal Title
  
  Biopolymers 88・2
  
  Pages: 272-278
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres.2007
- Author(s)
  Tomita K., Narumi T., Niida A., Oishi S., Ohno H., Fujii N.
- Journal Title
  
  Biopolymers 88
  
  Pages: 272-278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Zipper-mode double C-H activation : palladium-catalyzed direct construction of highly-fused heterocyclic systems.2007
- Author(s)
  Ohno H., Iuchi M., Fujii N., Tanaka T.
- Journal Title
  
  Org. Lett. 9
  
  Pages: 4813-4815
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] SAR and QSAR studies on the N-terminally acylated pentapeptide agonists for GPR54.2007
- Author(s)
  Tomita K., Oishi S., Cluzeau J., Ohno H., Navenot J. M., Wang Z. X., Peiper S. C., Akamatsu M., Fujii N.
- Journal Title
  
  J. Med. Chem. 50
  
  Pages: 3222-3228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] A Highly Regio- and Stereoselective Formation of Bicyclo[4.2.0]oct-5-ene Derivatives through Thermal Intramolecular [2+2] Cycloaddition2007
- Author(s)
  Ohno, H., Fujii, N., Tanaka, T.
- Journal Title
  
  J.Org.Chem. (in press)
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Structure-activity relationships of cyclic Peptide-based chemokine receptor CXCR4 antagonists : disclosing the importance of side-chain and backbone functionalities.2007
- Author(s)
  Ueda, S., Ohno, H., Fujii, N.et al.
- Journal Title
  
  J.Med.Chem. 50・2
  
  Pages: 192-198
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Association of nucleophosmin negatively regulates CXCR4-mediated G protein activation and chemotaxis.2007
- Author(s)
  Zhang W., Navenot J. M., Frilot N. M., Fujii N., Peiper S. C.
- Journal Title
  
  Mol. Pharmacol. 72
  
  Pages: 1310-1321
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment.2007
- Author(s)
  Juarez, J., Fujii, N., Bendall, L.J.et al.
- Journal Title
  
  Leukemia (in press)
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Development of copper-mediated allylation of γ-activated-α,β-unsaturated lactam toward peptide mimetic synthesis.2007
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.t al.
- Journal Title
  
  Tetrahedron Lett. 48・18
  
  Pages: 3221-3224
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Direct Synthesis of 2-(Aminomethyl)indoles through Copper(I)-Catalyzed Domino Three-Component Coupling and Cyclization Reactions.2007
- Author(s)
  Ohno, H., Fujii, N.et al.
- Journal Title
  
  Angew.Chem.Int.Ed.Engl. 46・13
  
  Pages: 2295-2298
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] CXCR4 engagement promotes dendritic cell survival and maturation.2007
- Author(s)
  Kabashima K., Sugita K., Shiraishi N., Tamamura H., Fujii N., Tokura Y.
- Journal Title
  
  Biochem. Biophys. Kes. Commun. 361
  
  Pages: 1012-1016
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Systematc solution-phase parallel synthesis of active vitamin D3 analogs with elongated side chains and their cell differentiation activities.2007
- Author(s)
  Ono Y., Kashiwagi H., Esaki T., Tadakatsu T., Sato H., Fujii N.
- Journal Title
  
  J. Comb. Chem. 9
  
  Pages: 711-716
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Structure-activity relationships of cyclic Peptide-based chemokine receptor CXCR4 antagonists : disclosing the importance of side-chain and backbone functionalities.2007
- Author(s)
  Ueda, S., Oishi, S., Fujii, N.et al.
- Journal Title
  
  J.Med.Chem. 50・2
  
  Pages: 192-198
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Gold-catalyzed hydroarylation of allenes : a highly regioselective carbon-carbon bond formation producing sixmembered rings.2007
- Author(s)
  Watanabe T., Oishi S., Fujii N., Ohno H.
- Journal Title
  
  Org. Lett. 9
  
  Pages: 4821-4824
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Bromoallenes as allyl dication equivalents in the presence or absence of palladlum(O) : direct construction of bicyclic sulfamides containing five- to eight-membered rings by tandem cyclization of bromoallenes2007
- Author(s)
  Hamaguchu, H., Ohno, H., Fujii, N., Tanaka, T.et al.
- Journal Title
  
  Chem.Eur.J. 13・6
  
  Pages: 1692-1708
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Structure-activity relationships of cyclic Peptide-based chemokine receptor CXCR4 antagonists : disclosing the importance of side-chain and backbone functionalities.2007
- Author(s)
  Ueda, S., Ohno, H., Fujii, N.et al.
- Journal Title
  
  J.Med.Chem. 50・2
  
  Pages: 192-198
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Development of low molecular weight CXCR4 antagonists by exploratory structural tuning of cyclic tetra- and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis.2007
- Author(s)
  Tamamura H., Tsutsumi H., Masuno H., Fujii N.
- Journal Title
  
  Curr. Med. Chem. 14
  
  Pages: 93-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] SAR and QSAR studies on the N-terminally acylated pentapeptide agonists for GPR542007
- Author(s)
  Fujii N., Ohno H., Oishi, S., et. al.
- Journal Title
  
  J. Med. Chem. 50
  
  Pages: 3222-3228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and G(alpha)(i) activation.2007
- Author(s)
  Berchiche, Y.A., Fujii, N., Heveker, N.et al.
- Journal Title
  
  J. Biol. Chem. 282・8
  
  Pages: 5111-5115
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and G(alpha)(i) activation.2007
- Author(s)
  Berchiche, Y.A., Fujii, N., Heveker, N.et al.
- Journal Title
  
  J.Biol.Chem. 282・8
  
  Pages: 5111-5115
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Development of plasmacytoid dendritic cells in bone marrow stromal cell niches requires CXCL12-CXCR4 chemokine signaling.2007
- Author(s)
  Kohara H., Omatsu Y., Sugiyama T., Noda M., Fujii N., Nagasawa T.
- Journal Title
  
  Blood 110
  
  Pages: 4153-4160
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] A highly regio- and stereoselective formation of bicyclo[4.2.0]oct-5-ene derivatives through thermal intramolecular [2 + 2] cycloaddition of allenes.2007
- Author(s)
  Ohno H., Mizutani T., Kadoh Y., Aso A., Miyamura K, Fujii N., Tanaka T.
- Journal Title
  
  J. Org. Chem. 72
  
  Pages: 4378-4389
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Facile synthesis of fluoroalkenes by palladium-catalyzed reductive defluorination of allylic gem-difluorides.2007
- Author(s)
  Narumi T., Tomita K., Inokuchi E., Kobayashi K., Oishi S., Ohno H., Fujii N.
- Journal Title
  
  Org. Lett. 9
  
  Pages: 3465-3468
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres.2007
- Author(s)
  Tomita, K., Oishi, S., Fujii, N.et al.
- Journal Title
  
  Biopolymers 88・2
  
  Pages: 272-278
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Direct Synthesis of 2-(Aminomethyl)indoles through Copper(I)-Catalyzed Domino Three-Component Coupling and Cyclization Reactions.2007
- Author(s)
  Ohno, H., Oishi, S., Fujii, N.et al.
- Journal Title
  
  Angew.Chem.Int.Ed.Engl. 46・13
  
  Pages: 2295-2298
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and G(alpha)(i) activation.2007
- Author(s)
  Berchiche, Y.A., Fujii, N., Heveker, N.et al.
- Journal Title
  
  J.Biol.Chem. 282・8
  
  Pages: 5111-5115
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment.2007
- Author(s)
  Juarez, J., Fujii, N., Bendall, L.J.et al.
- Journal Title
  
  Leukemia (in press)
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] A Highly Regio- and Stereoselective Formation of Bicyclo[4.2.0]oct-5-ene Derivatives through Thermal Intramolecular [2 + 2] Cycloaddition2007
- Author(s)
  Ohno, H., Fujii, N., Tanaka, T.
- Journal Title
  
  J.Org.Chem. (in press)
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling2007
- Author(s)
  Watanabe T., Ueda S., Inuki S., Oishi S., Fujii N., Ohno H.
- Journal Title
  
  Chem. Commun.
  
  Pages: 4516-4518
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Modulation of networkdriven, GABA-mediated giant depolarizing potentials by SDF-1a in the developing hippocampus.2007
- Author(s)
  Kasiyanov A., Fujii N., Tamamura H., Xiong H.
- Journal Title
  
  Dev. Neurosci. 30
  
  Pages: 285-292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Bromoallenes as allyl dication equivalents in the presence or absence of palladium(O) : direct construction of bicyclic sulfamides containing five- to eight-membered rings by tandem cyclization of bromoallenes.2007
- Author(s)
  Hamaguchi H., Kosaka S., Ohno H., Fujii N., Tanaka T.
- Journal Title
  
  Chem-Eur. J. 13
  
  Pages: 1692-1708
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres.2007
- Author(s)
  Tomita, K., Ohno, H., Fujii, N.et al.
- Journal Title
  
  Biopolymers 88・2
  
  Pages: 272-278
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Structure-activity relationships of cyclic Peptide-based chemokine receptor CXCR4 antagonists : disclosing the importance of side-chain and backbone functionalities.2007
- Author(s)
  Ueda, S., Oishi, S., Fujii, N.et al.
- Journal Title
  
  J. Med. Chem. 50・2
  
  Pages: 192-198
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Rapid hematopoietic progenitor mobilization by sulfated colominic acid.2007
- Author(s)
  Kubonishi S., Kikuchi T., Yamaguchi S., Tamamura H., Fujii N., Watanabe T., Arenzana-Seisdedos F., Ikeda K., Matsui T., Tanimoto M., Katayama Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 355
  
  Pages: 970-975
- NAID
  120001384686
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of low molecular weight CXCR4 antagonists by exploratory structural tuning or cyclic tetra- and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis2007
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  Curr Med Chem 14・1
  
  Pages: 93-102
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Zipper-mode double C-H activation: palladium-catalyzed direct construction of highly-fused heterocyclic systems2007
- Author(s)
  Fujii N., Ohno H., et. al.
- Journal Title
  
  Org. Lett. 9
  
  Pages: 4813-4815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] A novel oxazolidine linker for the synthesis of peptide aldehydes.2007
- Author(s)
  Tanaka M., Oishi S., Ohno H., Fujii N.
- Journal Title
  
  Int. J. Pep. Res. Ther. 13
  
  Pages: 271-279
- NAID
  10020528946
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres.2007
- Author(s)
  Tomita, K., Ohno, H., Fujii, N.et al.
- Journal Title
  
  Biopolymers 88・2
  
  Pages: 272-278
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Bromoallenes as allyl dication equivalents in the presence or absence of palladium(O) : direct construction of bicyclic sulfamides containing five- to eight-membered rings by tandem cyclization of bromoallenes.2007
- Author(s)
  Hamaguchu, H., Ohno, H., Fujii, N., Tanaka, T.et al.
- Journal Title
  
  Chem.Eur.J. 13・6
  
  Pages: 1692-1708
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Synthesis of (Z)-alkenecontaining cis-proline dipeptide mimetics using samarium (II) diiodide (SmI2)-mediated reductive-alkylation reaction.2007
- Author(s)
  Sasaki Y., Shigenaga A., Fujii N., Otaka A.
- Journal Title
  
  Tetrahedron 63
  
  Pages: 2000-2008
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Facile synthesis of fluoroalkenes by palladium-catalyzed reductive defluorination of allylic gem-difluorides2007
- Author(s)
  Fujii N., Ohno H., Oishi, S., et. al.
- Journal Title
  
  Org. Lett. 9
  
  Pages: 3465-3468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Development of low molecular weight CXCR4 antagonists by exploratory structural tuning of cyclic tetra- and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis.2007
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  Curr Med Chem 14・1
  
  Pages: 93-102
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment.2007
- Author(s)
  Juarez, J., Fujii, N., Bendall, L.J.et al.
- Journal Title
  
  Leukemia (in press)
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Heck-type cyclization of oxime ethers: stereoselective carbon-carbon bond formation with aryl halides to produce heterocyclic oximes2007
- Author(s)
  Fujii N., Ohno H., et. al.
- Journal Title
  
  Angew. Chem. Int. Ed. 46
  
  Pages: 6325-6328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Bromoallenes as allyl dication equivalents in the presence or absence of palladium(O) : direct construction of bicyclic sulfamides containing five-to eight-membered rings by tandem cyclization of bromoallenes.2007
- Author(s)
  Hamaguchu, H., Ohno, H., Fujii, N., Tanaka, T.et al.
- Journal Title
  
  Chem. Eur. J. 13・6
  
  Pages: 1692-1708
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.2007
- Author(s)
  Ogo N., Oishi S., Matsuno K., Sawada J., Fujii N., Asai A.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 17
  
  Pages: 3921-3924
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment.2007
- Author(s)
  Juarez J., Dela Pena A., Baraz R., Hewson J., Khoo M., Cisterne A., Frickei S., Fujii N., Bradstock K. F., Bendall L. J.
- Journal Title
  
  Leukemia 21
  
  Pages: 1249-1257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure.2006
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  J. Med. Chem. 49・11
  
  Pages: 3412-3415
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Structure-activity relationship study on small peptidic GPR54 agonists.2006
- Author(s)
  Tomita, K., Ohno, H., Fujii, N.et al.
- Journal Title
  
  Bioorg.Med.Chem. 45・22
  
  Pages: 7595-7603
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] The chemokine receptor CXCR4 as a therapeutic target for several disease.2006
- Author(s)
  Tamamura, H., Tsutsumi, H., Fujii, N.
- Journal Title
  
  Mini.Rev.Med.Chem. 6・9
  
  Pages: 989-995
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Stereoselective synthesis of (Z)-alkene-containing proline dipeptide mimetics2006
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  J.Org.Chem. 71・13
  
  Pages: 4969-4979
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] The Chemokine Receptor CXCR4 as a Therapeutic Target for Several Diseases2006
- Author(s)
  Tamamura H, Tsutumi A, Fujii N
- Journal Title
  
  Mini-Reviews in Medicinal Chemistry 6
  
  Pages: 109-120
- Data Source
  KAKENHI-PROJECT-16659029
[Journal Article] Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs.2006
- Author(s)
  Tamamura H., Tsutsumi H., Masuno H., Mizokami S., Hiramatsu K., Wang Z., Trent J. O., Nakashima H., Yamamoto N., Peiper S. C., Fujii N.
- Journal Title
  
  Org. Biomol. Chem. 4
  
  Pages: 2354-2357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs.2006
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  Org.Biomol.Chem. 4・12
  
  Pages: 2354-2357
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres2006
- Author(s)
  Narumi, T., Ohno, H., Fujii, N.et al.
- Journal Title
  
  Chem.Commun. 45
  
  Pages: 4720-2722
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents.2006
- Author(s)
  Tsutsumi H, Fujii N. et al.
- Journal Title
  
  Biopolymers 88・2
  
  Pages: 279-289
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Stereoselective synthesis of (Z)-alkene-containing proline dipeptide mimetics2006
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  J. Org. Chem. 71・13
  
  Pages: 4969-4979
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Stereoselective synthesis of (Z)-alkene-containing proline dipeptide mimetics2006
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  J.Org.Chem. 71・13
  
  Pages: 4969-4979
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Structure-activity relationship study on small peptidic GPR54 agonists.2006
- Author(s)
  Tomita K., Niida A., Oishi S., Ohno H., Cluzeau J., Navenot J. M., Wang Z. X., Peiper S. C., Fujii N.
- Journal Title
  
  Bioorg. Med. Chem. 14
  
  Pages: 7595-7603
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Structure-activity relationship study on small peptidic GPR54 agonists.2006
- Author(s)
  Tomita, K., Oishi, S., Fujii, N.et al.
- Journal Title
  
  Bioorg. Med. Chem. 45・22
  
  Pages: 7595-7603
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Synthesis of (Z)-alkene and (E)-fluoroalkene-containing diketopiperazine mimetics utili-zing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations.2006
- Author(s)
  Niida, A., Oishi, S., Fujii, N.et al.
- Journal Title
  
  J. Org. Chem. 71・11
  
  Pages: 4118-4129
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] The chemokine receptor CXCR4 as a therapeutic target for several diseases.2006
- Author(s)
  Tamamura, H., Tsutsumi, H., Fujii, N.
- Journal Title
  
  Mini.Rev.Med.Chem. 6・9
  
  Pages: 989-995
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres.2006
- Author(s)
  Narumi T., Niida A., Tomita K., Oishi S., Otaka A., Ohno H., Fujii N.
- Journal Title
  
  Chem. Commun.
  
  Pages: 4720-4722
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] The chemokine receptor CXCR4 as a therapeutic target for several diseases.2006
- Author(s)
  Tamamura, H., Tsutsumi, H., Fujii, N.
- Journal Title
  
  Mini.Rev.Med.Chem. 6・9
  
  Pages: 989-995
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Application of tri- and tetrasubstituted alkene dipeptide mimetics to conformational studies of cyclic RGD peptides2006
- Author(s)
  Oishi S., Miyamoto K., Niida A., Yamamoto M., Ajito K., Tamamura H., Otaka A., Kuroda Y., Asai A., Fujii N.
- Journal Title
  
  Tetrahedron 62
  
  Pages: 1416-1424
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] The involvement of stromal derived factor la in homing and progression of multiple myeloma in the 5TMM model.2006
- Author(s)
  Menu E., Asosingh K., Indraccolo S., De Raeve H., Van Riet I., Van Valckenborgh E., Van de Broek I, Fujii N., Tamamura H., Van Camp B., Vanderkerken K.
- Journal Title
  
  Haematologica 91
  
  Pages: 605-612
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] HIV-1 gpl20 enhances giant depolarizing potentials via chemokine receptor CXCR4 in neonatal rathippocampus.2006
- Author(s)
  Kasyanov A., Tamamura H., Fujii N., Xiong H.
- Journal Title
  
  Eur. J. Neurosci. 23
  
  Pages: 1120-1128
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Transport characteristics of a novel PEPT1 substrate, antihypotensive drug midodrine, and its amino acid derivatives.2006
- Author(s)
  Tsuda M., Terada T., Me M., Katsura T., Niida A., Tomita K., Fujii N., Inui K.
- Journal Title
  
  J. Pharmacol. Exp. Ther. 318
  
  Pages: 455-460
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Unequivocal synthesis of (Z)-alkene and (E)-fluoroalkene dipeptide isosteres to probe structural requirements of the peptide transporter PEPT1.2006
- Author(s)
  Niida A., Tomita K., Mizumoto M., Tanigaki H., Terada T., Oishi S., Otaka A., Inui K., Fujii N.
- Journal Title
  
  Org. Lett. 8
  
  Pages: 613-616
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Structure-activity relationship study on small peptidic GPR54 agonists.2006
- Author(s)
  Tomita, K., Ohno, H., Fujii, N.et al.
- Journal Title
  
  Bioorg.Med.Chem. 45・22
  
  Pages: 7595-7603
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs.2006
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  Org.Biomol.Chem. 4・12
  
  Pages: 2354-2357
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Synthesis of (Z)-alkene and (E)- fluoroalkene-containing diketopiperazine mimetics utili-zing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations2006
- Author(s)
  Niida, A., Ohno, H., Fujii, N.et al.
- Journal Title
  
  J.Org.Chem. 71・11
  
  Pages: 4118-4129
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure.2006
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  J.Med.Chem. 49・11
  
  Pages: 3412-3415
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Syntnesis of (Z)-alkene and (E)-fluoroalkene-containing diketoplperazine mimetics utin-zing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations2006
- Author(s)
  Niida, A., Ohno, H., Fujii, N.et al.
- Journal Title
  
  J.Org.Chem. 71・11
  
  Pages: 4118-4129
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Structure-activity relationship study on small peptidic GPR54 agonists.2006
- Author(s)
  Tomita, K., Oishi, S., Fujii, N.et al.
- Journal Title
  
  Bioorg.Med.Chem. 45・22
  
  Pages: 7595-7603
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents.2006
- Author(s)
  Tsutsumi H, Fujii N. et al.
- Journal Title
  
  Biopolymers 88・2
  
  Pages: 279-289
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Synthesis of (Z)-alkene and (E)-fluoroalkenecontaining diketopiperazine mimetics utilizing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT2006
- Author(s)
  Niida A., Mizumoto M., Narumi T., Inokuchi E., Oishi S., Ohno H., Otaka A., Kitaura K., Fujii N.
- Journal Title
  
  J. Org. Chem. 71
  
  Pages: 4118-4129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure.2006
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  J.Med.Chem. 49・11
  
  Pages: 3412-3415
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents.2006
- Author(s)
  Tsutsumi H, Fujii N. et al.
- Journal Title
  
  Biopolymers 88・2
  
  Pages: 279-289
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] The chemokine receptor CXCR4 as atherapeutic target for several diseases.2006
- Author(s)
  Tamamura H., Tstsumi H., Fujii N.
- Journal Title
  
  Mini Rev. Med. Chem. 6
  
  Pages: 989-995
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] A-nover one-pot reaction involving orgamcopper-mediated reduction/transmealation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres2006
- Author(s)
  Narumi, T., Ohno, H., Fujii, N.et al.
- Journal Title
  
  Chem.Commun. 45
  
  Pages: 4720-2722
- Data Source
  KAKENHI-PROJECT-18659027
[Journal Article] The chemokine receptor CXCR4 as a therapeutic target for several diseases.2006
- Author(s)
  Tamamura, H., Tsutsumi, H., Fujii, N.
- Journal Title
  
  Mini. Rev. Med. Chem. 6・9
  
  Pages: 989-995
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure.2006
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  J.Med.Chem. 49・11
  
  Pages: 3412-3415
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure.2006
- Author(s)
  Tamamura H., Ojida A., Ogawa T., Tsutsumi H., Masuno H., Nakashima H., Yamamoto N., Hamachi I., Fujii N.
- Journal Title
  
  J. Med. Chem. 49
  
  Pages: 3412-3415
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres.2006
- Author(s)
  Narumi, T., Oishi, S., Fujii, N.et al.
- Journal Title
  
  Chem. Commun. 45
  
  Pages: 4720-2722
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of a lllln-labeled peptide derivative targeting a chemokine receptor, CXCR4, for imaging tumors.2006
- Author(s)
  Hanaoka H., Mukai T., Tamamura H., Mori T., Ishino S., Ogawa K., Iida Y., Doi R., Fujii N., Saji H.
- Journal Title
  
  Nucl. Med. Biol. 33
  
  Pages: 489-494
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Stereoselective synthesis of (Z)-alkene-containing proline dipeptide mimetics2006
- Author(s)
  Sasaki Y., Niida A., Tsuji T., Shigenaga A., Fujii N., Otaka A.
- Journal Title
  
  J. Org. Chem. 71
  
  Pages: 4969-49679
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres.2006
- Author(s)
  Narumi, T., Oishi, S., Fujii, N.et al.
- Journal Title
  
  Chem.Commun. 45
  
  Pages: 4720-4722
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents.2006
- Author(s)
  Tsutsumi H, Fujii N. et al.
- Journal Title
  
  Biopolymers 88・2
  
  Pages: 279-289
- Data Source
  KAKENHI-PROJECT-18015027
[Journal Article] Stereoselective synthesis of (Z)-alkene-containing proline dipeptide mimetics2006
- Author(s)
  Sasaki, T., Fujii, N., Otaka, A.et al.
- Journal Title
  
  J.Org.Chem. 71・13
  
  Pages: 4969-4979
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Cysteinederived S-protected oxazolidinones: potential chemical devices for the preparation of peptide thioesters.2006
- Author(s)
  Ohta Y., Itoh S., Shigenaga A., Shintaku S., Fujii N., Otaka A.
- Journal Title
  
  Org. Lett. 8
  
  Pages: 467-470
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs.2006
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  Org. Biomol. Chem. 4・12
  
  Pages: 2354-2357
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity2006
- Author(s)
  Niida A., Wang Z., Tomita K, Oishi S., Tamamura H., Otaka A., Navenot J. M., Broach J. R., Peiper S. C., Fujii N.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 16
  
  Pages: 134-137
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of antiviral fusion inhibiting peptides.2006
- Author(s)
  Otaka A., Fujii N.
- Journal Title
  
  Kagaku Kogyo 57
  
  Pages: 797-801
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Potassium carbonate-promoted stereospecific 5-endo-trig cyclization of unactivated allenes in the absence of any transition metals.2006
- Author(s)
  Ohno H., Kadoh Y., Fujii N., Tanaka T.
- Journal Title
  
  Org. Lett. 8
  
  Pages: 947-950
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Stereoselective synthesis of 3,6-disubstituted-3,6-dihydropyridin-2-ones as potential diketopiperazine mimetics using organocopper-mediated anti-SN2' reactions and their use in the preparation of low-molecule CXCR4 antagonists.2006
- Author(s)
  Niida A., Tanigaki H., Inokuchi E., Sasaki Y., Oishi S., Ohno H., Tamamura H., Wang Z., Peiper S. C., Kitaura K., Otaka A., Fujii N.
- Journal Title
  
  J. Org. Chem. 71
  
  Pages: 3942-3951
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Synthesis of (Z)-alkene and (E)- fluoroalkene-containing diketopiperazine mimetics utili-zing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations.2006
- Author(s)
  Niida, A., Oishi, S., Fujii, N.et al.
- Journal Title
  
  J.Org.Chem. 71・11
  
  Pages: 4118-4129
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs.2006
- Author(s)
  Tamamura, H., Fujii, N.et al.
- Journal Title
  
  Org.Biomol.Chem. 4・12
  
  Pages: 2354-2357
- Data Source
  KAKENHI-PROJECT-18060020
[Journal Article] Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds.2005
- Author(s)
  Tamamura H., Esaka A., Ogawa T., Araki T., Ueda S., Wang Z., Trent J. O., Tsutsumi H., Masuno H., Nakashima H., Yamamoto N., Peiper S. C., Otaka A., Fujii N.
- Journal Title
  
  Org. Biomol. Chem. 3
  
  Pages: 4392-4394
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] The therapeutic potential of CXCR4 antagonists in the treatment of HIV infection, cancer metastasis and rheumatoid arthritis.2005
- Author(s)
  Tamamura H, Fujii N
- Journal Title
  
  Expert Opin Ther Targets 9
  
  Pages: 1267-1282
- Data Source
  KAKENHI-PROJECT-16659029
[Journal Article] Innovative platform for drug discovery based on chemical proteomics: from knowledge to controlling.2005
- Author(s)
  Fujii N., Otaka A., Tamamura H.
- Journal Title
  
  Saibo Kogaku 24
  
  Pages: 1181-1186
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Photolabile protection for one-pot sequential native chemical ligation.2005
- Author(s)
  Ueda S., Pujita M., Tamamura H., Fujii N., Otaka A.
- Journal Title
  
  ChemBioChem 6
  
  Pages: 1983-1986
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] New HIV-drug inhibits in vitro bladder cancer migration and invasion.2005
- Author(s)
  Retz M., Sidhu S. S., Lehmann J., Tamamura H., Fujii N., Basbaum C.
- Journal Title
  
  Eur. Urol. 48
  
  Pages: 1025-1030
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice : implications for CXCL12/CXCR4 axis in lymphoma generation.2005
- Author(s)
  E.Piovan H.Tamamura, N.Fujii, et al.
- Journal Title
  
  Blood 105
  
  Pages: 931-939
- Data Source
  KAKENHI-PROJECT-16023235
[Journal Article] Stereoselective Synthesis of [L-Arg, L/D-3-(2-naphthyl)alanine]-Type (E)-Alkene Dipeptide Isosteres and its Application to the Synthesis and Biological Evaluation of Pseudopeptide Analogs of the CXCR4 Antagonist FC131.2005
- Author(s)
  H.Tamamura, N.Fujii, S.C.Peiper et al.
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 380-391
- Data Source
  KAKENHI-PROJECT-16023235
[Journal Article] Kisspeptin-10induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: a potential mechanism for the metastasis suppressor activity of kisspeptins.2005
- Author(s)
  Navenot J. M., Wang Z., Chopin M., Fujii N., Peiper S. C.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 10450-10456
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Stereoselective Synthesis of [L-Arg, L/D-3-(2-naphthyl)alanine]-Type(E)-Alkene Dipeptide Isosteres and its Application to the Synthesis and Biological Evaluation of Pseudopeptide Analogs of the CXCR4 Antagonist FC131.2005
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 380-391
- Data Source
  KAKENHI-PROJECT-16659029
[Journal Article] Mutations Conferring Resistance to Human Immunodeficiency Virus Type 1 Fusion Inhibitors Are Restricted by gp41 and Rev-Responsive Element Functions.2005
- Author(s)
  D.Nameki, M.Matsuoka, N.Fujii, et al.
- Journal Title
  
  J.Virology 79
  
  Pages: 764-770
- Data Source
  KAKENHI-PROJECT-16659029
[Journal Article] The therapeutic potential of CXCR4 antagonists in the treatment of HIV infection, cancer metastasis and rheumatoid arthritis2005
- Author(s)
  Tamamura H., Fujii N.
- Journal Title
  
  Exp. Opin. Ther. Target 9
  
  Pages: 1267-1282
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Development of anti-HIV agents targeting dynamic supramolecular mechanism : entry and fusion inhibitors based on CXCR4/CCR5 antagonists and gp41-C34-remodeling peptides.2005
- Author(s)
  Tamamura H, Otaka A, Fujii N.
- Journal Title
  
  Curr HIV Res 3
  
  Pages: 289-301
- Data Source
  KAKENHI-PROJECT-16659029
[Journal Article] Germinal Center Dark and Light Zone Organization Is Mediated by CXCR4 and CXCR5.2004
- Author(s)
  C.D.C.Allen, H.Tamamura, N.Fujii, J.G.Cyster, et al.
- Journal Title
  
  Nature Immunol. 5
  
  Pages: 943-952
- Data Source
  KAKENHI-PROJECT-16023235
[Journal Article] Identification of a CXCR4 Antagonist, a T140 Analog, as an Anti-rheumatoid Arthritis Agent.2004
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  FEBS Lett. 569・1
  
  Pages: 99-104
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] SmI2-mediated Reduction of γ,γ-Difluoro-_α,β-enoates and Its Application to the Synthesis of (Z)-Fluoroalkene-type Dipeptide Isosteres2004
- Author(s)
  A.Otaka, J.Watanabe, N.Fujii, et al.
- Journal Title
  
  J.Org.Chem. 69
  
  Pages: 1634-1645
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Facile Synthesis of Membrane-embedded Peptides Utilizing Lipid Bilayer-assisted Chemical Ligation.2004
- Author(s)
  A.Otaka, S.Ueda, N.Fujii, et al.
- Journal Title
  
  Chem.Commun. 7
  
  Pages: 1722-1723
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] HIV protease inhibitor, nelfinavir, inhibits replication of SARS-associted coronavirus.2004
- Author(s)
  N.Yamamoto, N.Fujii, et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 318
  
  Pages: 719-725
- Data Source
  KAKENHI-PROJECT-16659029
[Journal Article] Two Orthogonal Approaches to Overcome Multi-Drug Resistant HIV-ls : Development of Protease Inhibitors and Entry Inhibitors Based on CXCR4 Antagonists.2004
- Author(s)
  H.Tamamura, N.Fujii
- Journal Title
  
  Curr.Drug Targets-Infectious Disorders 4・2
  
  Pages: 103-110
- Data Source
  KAKENHI-PROJECT-16659029
[Journal Article] CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer.2004
- Author(s)
  T.Mori, R.Doi, N.Fujii, et al.
- Journal Title
  
  Molecular Cancer Therapeutics 3
  
  Pages: 29-37
- Data Source
  KAKENHI-PROJECT-16023235
[Journal Article] Germinal Center Dark and Light Zone Organization Is Mediated by CXCR4 and CXCR5.2004
- Author(s)
  C.D.C.Allen, H.Tamamura, N.Fujii, J.G.Cyster, et al.
- Journal Title
  
  Nature Immunol. 5
  
  Pages: 943-952
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] A Single Treatment with Microcapsules Containing a CXCR4 Antagonist Suppresses Pulmonary Metastasis of Murine Melanoma.2004
- Author(s)
  M.Takenaga, H.Tamamura, N.Fujii, et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 320・1
  
  Pages: 226-232
- Data Source
  KAKENHI-PROJECT-16023235
[Journal Article] Synthesis of Fluorine-Containing Bioisosteres Corresponding to Phosphoamino Acids and Dipeptide Units2004
- Author(s)
  A.Otaka, E.Mitsuyama, N.Fujii, et al.
- Journal Title
  
  Biopolymers 76
  
  Pages: 140-149
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Germinal Center Dark and Light Zone Organization Is Mediated by CXCR4 and CXCR5.2004
- Author(s)
  C.D.C.Allen, H.Tamamura, N.Fujii, J.G.Cyster, et al.
- Journal Title
  
  Nat.Immunol. 5
  
  Pages: 943-952
- Data Source
  KAKENHI-PROJECT-16659029
[Journal Article] Topochemical Exploration of Potent Compounds Using Retro-Enantiomer Libraries of Cyclic Pentapeptides.2004
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  Org.Biomol.Chem. 2
  
  Pages: 1255-1257
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Functional Expression of CXCR4 in Scerevisiae : Development of Tools for Mechanistic and Pharmacologic Studies.2004
- Author(s)
  H.Zhang, H.Tamamura, N.Fujii, S.C.Peier et al.
- Journal Title
  
  Chemokine Roles in Immunoregulation and Disease 45
  
  Pages: 125-152
- Data Source
  KAKENHI-PROJECT-16023235
[Journal Article] Indium-modiated Atom-transfer and Reductive Radical Cyclizations of Iodoalkynes : Synthesis and Biological Evaluation of HIV-Protease Inhibitors.2004
- Author(s)
  R.Yanada, Y.Takemoto, H.Mitsuya, N.Fujii, et al.
- Journal Title
  
  J.Org.Chem., 69
  
  Pages: 2417-2422
- Data Source
  KAKENHI-PROJECT-16659029
[Journal Article] The Therapeutic Potential of CXCR4 Antagonists in the Treatment of HIV.2003
- Author(s)
  N.Fujii, et al.
- Journal Title
  
  Expert Opinion on Investigational Drugs 12
  
  Pages: 185-195
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Molecular Size Reduction of a Potent CXCR4-Chemokimne Antagonists Using Orthogona Combination of Conformation-based and Sequence-based Libraries.2003
- Author(s)
  N.Fujii, et al.
- Journal Title
  
  Angew.Chem.Int Ed.Engl. 42(28)
  
  Pages: 3251-3253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] The Therapeutic Potential of CXCR4 Antagonists in the Treatment of HIV.2003
- Author(s)
  N.Fujii, et al.
- Journal Title
  
  Expert Opinion on Investigational Drugs 12(2)
  
  Pages: 185-195
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Molecular Size Reduction of a Potent CXCR4-Chemokimne Antagonists Using Orthogona Combination of Conformation-based and Sequence-based Libraries.2003
- Author(s)
  N.Fujii, et al.
- Journal Title
  
  Angew.Chem.Int Ed.Engl. 42
  
  Pages: 3251-3253
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Coiled-coil tag-probe system for quick labeling of membrane receptors in living cells.
- Author(s)
  Yano Y., Yano A., Oishi S., Sugimoto Y., Tsujimoto G., Fujii N., Matsuzaki K.
- Journal Title
  
  ACS Chem. Biol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Identification of novel nonpeptide CXCR4 antagonists by ligand-based design approach.
- Author(s)
  Ueda S., Kato M., Inuki S., Ohno H., Evans B., Wang Z., Peiper S. C., Izumi K., Kodama E., Matsuoka M., Nagasawa H., Oishi S., Fujii N.
- Journal Title
  
  Bioorg. Med. Chem. Lett. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Novel screening systems for HIV-1 fusion mediated by two extra-virion heptad repeats of gp41.
- Author(s)
  Nishikawa H., Kodama E., Sakakibara A., Fukudome A., Izumi K., Oishi S., Fujii N., Matsuoka M.
- Journal Title
  
  Antivir. Res. (in press)
- NAID
  120002790066
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Structure-activity relationship of pyrazine-based CK2 inhibitors : synthesis and biological evaluation of 2,6-disubstituted pyrazine and 4,6-disubstituted pyrimidine derivatives.
- Author(s)
  Suzuki Y., Cluzeau J., Hara T., Hirasawa A.. Tsujimoto G., Oishi S., Ohno H., Fujii N.
- Journal Title
  
  Archiv. Pharm. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Palladiumcatalysed biscyclisation of allenic bromoalkenes through zipper-mode cascade.
- Author(s)
  Okano A., Mizutani T., Oishi S., Tanaka T., Ohno H., Fujii N.
- Journal Title
  
  Chem. Commun. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Structure-activity relationship study and NMR analysis of fluorobenzoyl pentapeptide GPR54 agonists.
- Author(s)
  Tomita K., Oishi S., Ohno H., Fujii N.
- Journal Title
  
  Biopolymers (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Journal Article] Potent synergistic anti-HIV effects using combinations of a CCR5. inhibitor aplaviroc with other anti-HIV drugs.
- Author(s)
  Nakata H., Steinberg S. M., Koh Y., Maeda K., Takaoka Y, Tamamura H., Fujii N., Mitsuya H.
- Journal Title
  
  Antimicroh. Agents. Chemother. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] ベンゾイソチアゾロピリミジン誘導体またはその塩,およびウイルス感染阻害剤ならびに医薬品2014
- Inventor(s)
  松岡雅雄、　志村和也、藤井信孝、大野浩章、大石真也、岡崎志穂　他
- Industrial Property Rights Holder
  松岡雅雄、　志村和也、藤井信孝、大野浩章、大石真也、岡崎志穂　他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-206613
- Filing Date
  2014-10-07
- Data Source
  KAKENHI-PROJECT-23390025
[Patent] ＣＸＣＲ７結合剤およびＣＸＣＲ７結合剤を含有する医薬組成物2014
- Inventor(s)
  藤井信孝、大野浩章、大石真也、黒柳友子、久保達彦他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-195189
- Filing Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-23390025
[Patent] Eg5阻害剤2014
- Inventor(s)
  藤井信孝、大野浩章、大石真也、竹内智起、浅井章良、澤田潤一
- Industrial Property Rights Holder
  京都大学、ファルマバレープロジェクト支援機構
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-25
- Overseas
- Data Source
  KAKENHI-PROJECT-23390025
[Patent] 新規ケモカイン受容体拮抗剤2012
- Inventor(s)
  藤井信孝、大野浩章、大石真也、他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-02-29
- Overseas
- Data Source
  KAKENHI-PROJECT-23390025
[Patent] ピリミドベンゾチアジン6-イミン誘導体またはその塩を含有するウイルス感染症の治療および／または予防のための薬剤2012
- Inventor(s)
  前田英樹、加藤貴之、藤井信孝、他
- Industrial Property Rights Holder
  国立大学法人京都大学、富士フイルム株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2012-05-09
- Overseas
- Data Source
  KAKENHI-PROJECT-23390025
[Patent] キナーゼ阻害剤2012
- Inventor(s)
  辻本豪三、平澤明、藤井信孝、他
- Industrial Property Rights Holder
  国立大学法人京都大学、学校法人近畿大学、公立大学法人大阪府立大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-03-02
- Overseas
- Data Source
  KAKENHI-PROJECT-23390025
[Patent] ピリミドベンゾチアジン6-イミン誘導体またはその塩を含有するウイルス感染症の治療および／または予防のための薬剤2011
- Inventor(s)
  前田英樹、加藤貴之、藤井信孝、他
- Industrial Property Rights Holder
  前田英樹、加藤貴之、藤井信孝、他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2011-105642
- Filing Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-23390025
[Patent] Metastin derivative and use thereof2009
- Inventor(s)
  Nobutaka Fujii, Shinya Oishi, Kenji Tomita
- Industrial Property Rights Holder
  Kyoto University, Takeda Pharmaceutical Company
- Industrial Property Rights Type
  特許
- Filing Date
  2009-04-28
- Acquisition Date
  2017-06-07
- Overseas
- Data Source
  KAKENHI-PROJECT-20057011
[Patent] METASTIN DERIVATIVE AND USE THEREOF2009
- Inventor(s)
  Nobutaka Fujii, Shinya Oishi, Kenji Tomita
- Industrial Property Rights Holder
  Kyoto University, Takeda Pharmaceutical Company
- Industrial Property Rights Type
  特許
- Filing Date
  2009-04-28
- Acquisition Date
  2013-11-26
- Overseas
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] メタスチン誘導体およびその用途2009
- Inventor(s)
  藤井信孝、大石真也、富田健嗣
- Industrial Property Rights Holder
  国立大学法人京都大学、武田薬品工業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2009-04-28
- Acquisition Date
  2015-02-27
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] Metastin derivative and use thereof2009
- Inventor(s)
  Nobutaka Fujii, Shinya Oishi, Kenji Tomita
- Industrial Property Rights Holder
  Kyoto University, Takeda Pharmaceutical Company
- Industrial Property Rights Type
  特許
- Filing Date
  2009-04-28
- Acquisition Date
  2017-06-07
- Overseas
- Data Source
  KAKENHI-PROJECT-20015021
[Patent] Eg5阻害剤2009
- Inventor(s)
  藤井信孝、大野浩章、大石真也, 他
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2009-12-25
- Overseas
- Data Source
  KAKENHI-PROJECT-20015021
[Patent] メタスチン誘導体およびその用途2009
- Inventor(s)
  藤井信孝、大石真也, 他
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2009-04-28
- Overseas
- Data Source
  KAKENHI-PROJECT-20015021
[Patent] メタスチン誘導体およびその用途2009
- Inventor(s)
  藤井信孝、大石真也, 他
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2009-04-28
- Overseas
- Data Source
  KAKENHI-PROJECT-20057011
[Patent] METASTIN DERIVATIVE AND USE THEREOF2009
- Inventor(s)
  Nobutaka Fujii, Shinya Oishi, Kenji Tomita
- Industrial Property Rights Holder
  Kyoto University, Takeda Pharmaceutical Company
- Industrial Property Rights Type
  特許
- Filing Date
  2009-04-28
- Acquisition Date
  2013-11-26
- Overseas
- Data Source
  KAKENHI-PROJECT-20015021
[Patent] メタスチン誘導体およびその用途2009
- Inventor(s)
  藤井信孝、大石真也、富田健嗣
- Industrial Property Rights Holder
  国立大学法人京都大学、武田薬品工業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2009-04-28
- Acquisition Date
  2015-02-27
- Data Source
  KAKENHI-PROJECT-20057011
[Patent] METASTIN DERIVATIVE AND USE THEREOF2009
- Inventor(s)
  Nobutaka Fujii, Shinya Oishi, Kenji Tomita
- Industrial Property Rights Holder
  Kyoto University, Takeda Pharmaceutical Company
- Industrial Property Rights Type
  特許
- Filing Date
  2009-04-28
- Acquisition Date
  2013-11-26
- Overseas
- Data Source
  KAKENHI-PROJECT-20057011
[Patent] Metastin derivative and use thereof2009
- Inventor(s)
  Nobutaka Fujii, Shinya Oishi, Kenji Tomita
- Industrial Property Rights Holder
  Kyoto University, Takeda Pharmaceutical Company
- Industrial Property Rights Type
  特許
- Filing Date
  2009-04-28
- Acquisition Date
  2017-06-07
- Overseas
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] メタスチン誘導体およびその用途2009
- Inventor(s)
  藤井信孝、大石真也、富田健嗣
- Industrial Property Rights Holder
  国立大学法人京都大学、武田薬品工業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2009-04-28
- Acquisition Date
  2015-02-27
- Data Source
  KAKENHI-PROJECT-20015021
[Patent] 新規CXCR4拮抗剤及びその用途2008
- Inventor(s)
  藤井、他
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2008-06-26
- Overseas
- Data Source
  KAKENHI-PROJECT-20015021
[Patent] 新規CXCR4拮抗剤及びその用途2008
- Inventor(s)
  藤井、他
- Industrial Property Rights Holder
  京都大学
- Acquisition Date
  2008-06-27
- Overseas
- Data Source
  KAKENHI-PROJECT-20057011
[Patent] 新規CXCR4拮抗剤及びその用途2008
- Inventor(s)
  藤井、他
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20015021
[Patent] Eg5阻害剤2008
- Inventor(s)
  藤井、大石, 他
- Industrial Property Rights Holder
  京都大学・ファルマIP
- Industrial Property Number
  2008-331963
- Filing Date
  2008-12-26
- Data Source
  KAKENHI-PROJECT-20015021
[Patent] 新規CXCR4拮抗剤及びその用途2008
- Inventor(s)
  藤井、他
- Industrial Property Rights Holder
  京都大学
- Acquisition Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20057011
[Patent] 新規CXCR4拮抗剤及びその用途2008
- Inventor(s)
  藤井、他
- Industrial Property Rights Holder
  京都大学
- Acquisition Date
  2008-06-26
- Overseas
- Data Source
  KAKENHI-PROJECT-20057011
[Patent] メタスチン誘導体およびその用途2008
- Inventor(s)
  藤井信孝, 大石真也, 富田健嗣
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Number
  2008-119235
- Filing Date
  2008-04-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] 新規CXCR4拮抗剤およびその用途2008
- Inventor(s)
  藤井信孝, 浜地格, 王子田彰夫, 玉村啓和
- Industrial Property Rights Holder
  国立大学法人京都大学
- Acquisition Date
  2008-05-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] 新規CXCR4拮抗剤及びその用途2008
- Inventor(s)
  藤井、他
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2008-06-27
- Overseas
- Data Source
  KAKENHI-PROJECT-20015021
[Patent] メタスチン誘導体およびその用途2008
- Inventor(s)
  藤井、大石他
- Industrial Property Rights Holder
  京都大学・武田薬品工業
- Industrial Property Number
  2008-119235
- Filing Date
  2008-04-30
- Data Source
  KAKENHI-PROJECT-20057011
[Patent] メタスチン誘導体およびその用途2008
- Inventor(s)
  藤井、大石, 他
- Industrial Property Rights Holder
  京都大学・武田薬品工業
- Industrial Property Number
  2008-119235
- Filing Date
  2008-04-30
- Data Source
  KAKENHI-PROJECT-20015021
[Patent] コイルドコイルを利用した膜タンパク質標識方法2007
- Inventor(s)
  松崎勝巳, 矢野義明, 杉本幸彦, 辻本豪三, 藤井信孝
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Number
  2007-255648
- Filing Date
  2007-09-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] Eg5阻害剤および該化合物を含有してなる抗癌剤2007
- Inventor(s)
  浅井章良, 澤田潤一, 松野研司, 小郷尚久, 藤井信孝, 大石真也
- Industrial Property Rights Holder
  有限責任中間法人フアルマIP
- Industrial Property Number
  2007-069487
- Filing Date
  2007-03-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] GPR54アゴニスト活性を有する化合物2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2006-122305
- Filing Date
  2006-04-26
- Data Source
  KAKENHI-PROJECT-18659027
[Patent] N36結合ペプチドの製造方法2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  月桂冠株式会社
- Industrial Property Number
  2006-204827
- Filing Date
  2006-07-27
- Data Source
  KAKENHI-PROJECT-18659027
[Patent] 抗FIV剤2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学, 東京大学
- Industrial Property Number
  2006-242428
- Filing Date
  2006-09-07
- Data Source
  KAKENHI-PROJECT-18060020
[Patent] 抗HIV剤2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2006-290241
- Filing Date
  2006-10-25
- Data Source
  KAKENHI-PROJECT-18060020
[Patent] 抗FIV剤2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学, 東京大学
- Industrial Property Number
  2006-242428
- Filing Date
  2006-09-07
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] N36結合ペプチドの製造方法2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  月桂冠株式会社
- Industrial Property Number
  2006-204827
- Filing Date
  2006-07-27
- Data Source
  KAKENHI-PROJECT-18015027
[Patent] 抗FIV剤2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学, 東京大学
- Industrial Property Number
  2006-242428
- Filing Date
  2006-09-07
- Data Source
  KAKENHI-PROJECT-18659027
[Patent] 抗FIV剤2006
- Inventor(s)
  辻本元, 藤井信孝
- Industrial Property Rights Holder
  国立大学法人京都大学, 国立大学法人東京大学
- Industrial Property Number
  2006-242428
- Filing Date
  2006-09-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] 抗HIV剤2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2006-290241
- Filing Date
  2006-10-25
- Data Source
  KAKENHI-PROJECT-18659027
[Patent] N36結合ペプチドの製造方法2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  月桂冠株式会社
- Industrial Property Number
  2006-204827
- Filing Date
  2006-07-27
- Data Source
  KAKENHI-PROJECT-18060020
[Patent] GPR54アゴニスト活性を有する化合物2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2006-122305
- Filing Date
  2006-04-26
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] 抗FIV剤2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学, 東京大学
- Industrial Property Number
  2006-242428
- Filing Date
  2006-09-07
- Data Source
  KAKENHI-PROJECT-18015027
[Patent] 抗HIV剤2006
- Inventor(s)
  藤井信孝, 大石真也, 松岡雅雄, 児玉栄
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Number
  2006-290241
- Filing Date
  2006-10-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] GPR54アゴニスト活性を有する化合物2006
- Inventor(s)
  藤井信孝, 大石真也, 富田健嗣, 新居田歩
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Number
  2006-122305
- Filing Date
  2006-04-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] N36結合ぺプチドの製造方法2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  月桂冠株式会社
- Industrial Property Number
  2006-204827
- Filing Date
  2006-07-27
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] GPR54アゴニスト活性を有する化合物2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2006-122305
- Filing Date
  2006-04-26
- Data Source
  KAKENHI-PROJECT-18060020
[Patent] GPR54アゴニスト活性を有する化合物2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2006-122305
- Filing Date
  2006-04-26
- Data Source
  KAKENHI-PROJECT-18015027
[Patent] N36結合ペプチドの製造方法2006
- Inventor(s)
  堤, 石田, 久田, 水本, 秦, 藤井, 松岡, 児玉, 大石
- Industrial Property Rights Holder
  月桂冠株式会
- Industrial Property Number
  2006-204827
- Filing Date
  2006-07-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] 抗HIV剤2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2006-290241
- Filing Date
  2006-10-25
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] 抗HIV剤2006
- Inventor(s)
  藤井信孝他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2006-290241
- Filing Date
  2006-10-25
- Data Source
  KAKENHI-PROJECT-18015027
[Patent] CXCR4 antagonists for wound healing and reepithelialization2005
- Inventor(s)
  Amnon Peled, Nobutaka Fujii
- Industrial Property Rights Holder
  Hadasit Medical Research Services and Development Ltd. Kyoto University
- Filing Date
  2005-05-25
- Description
  「研究成果報告書概要(和文)」より
- Overseas
- Data Source
  KAKENHI-PROJECT-17209004
[Patent] 新規CXCR4拮抗剤およびその用途2005
- Inventor(s)
  藤井信孝, 浜地格, 王子田彰夫, 玉村啓和
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Number
  2006-326069
- Filing Date
  2005-12-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 新規KSP阻害薬のヒト乳癌細胞に対する効果2018
- Author(s)
  太田有紀、土屋聖子、武永美津子、新美純、渡邉大輝、大滝正訓、大石真也、藤井信孝、津川浩一郎、松本直樹
- Organizer
  第138年会日本薬学会
- Data Source
  KAKENHI-PROJECT-15K10074
[Presentation] ケモカイン受容体CXCR7選択的リガンドの構造最適化研究2017
- Author(s)
  関口遼、黒柳友子、小林由佳、藤井信孝、大野浩章、大石真也
- Organizer
  日本薬学会第137回年会
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] CXCR7受容体選択的リガンドの構造活性相関研究2017
- Author(s)
  関口遼、黒柳友子、小林由佳、小林数也、赤路健一、藤井信孝、大野浩章、大石真也
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] 鏡像体タンパク質を利用したc-Src SH2ドメイン阻害剤の探索法の開発2017
- Author(s)
  周敬棠、野口太朗、本田香織、近藤恭光、長田裕之、大野浩章、藤井信孝、大石真也
- Organizer
  日本薬学会第137回年会
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] Development of novel NK3 receptor antagonists with reduced environmental impact2017
- Author(s)
  Koki Yamamoto, Hiroaki Ohno, Nobutaka Fujii, Shinya Oishi
- Organizer
  254th ACS National Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] 4-epi-Jaspine B位置異性体の合成と構造活性相関研究2017
- Author(s)
  宮川貴吏、本田真歩、小林由佳、中村真也、仲西功、藤井信孝、井貫晋輔、大石真也、大野浩章
- Organizer
  第34回有機合成化学セミナー
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] 化学合成タンパク質を利用したc-Src SH2ドメイン阻害剤の探索法の開発2016
- Author(s)
  周敬棠、大石真也、野口太朗、大野浩章、藤井信孝
- Organizer
  日本ケミカルバイオロジー学会　第11回年会
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] Facile access to the mirror-image library of chiral natural product derivatives: identification of MDM2-p53 interaction inhibitor2016
- Author(s)
  Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
- Organizer
  第8回武田振興財団薬科学シンポジウム
- Place of Presentation
  武田研修センター（大阪府吹田市）
- Year and Date
  2016-01-21
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] Strictamineの不斉形式全合成2016
- Author(s)
  熊谷洋、西山大亮、大石真也、藤井信孝、大野浩章
- Organizer
  第42回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] Development of a screening system for Grb2 SH2 domain inhibitors using synthetic proteins2016
- Author(s)
  Taro Noguchi, Hiroyuki Ishiba, Kaori Honda, Yasumitsu Kondoh, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii, Shinya Oishi
- Organizer
  第53回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] 新規合成KSP阻害剤のヒト卵巣がんに対する抗腫瘍効果2016
- Author(s)
  武永美津子、竹内智起、山本有貴、都倉享恵、新美純、濱口明美、太田有紀、浅井大輔、大石真也、中島秀喜、藤井信孝
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  パシフィコ横浜、横浜市西区
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K01319
[Presentation] Design of iron-chelating cyclic peptides2016
- Author(s)
  Yuka Kobayashi, Shinya Oishi, Hiroaki Ohno, Nobutaka Fujii
- Organizer
  8th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] Development of screening systems for c-Src SH2 domain inhibitors using synthetic proteins2016
- Author(s)
  Keitou Shu, Taro Noguchi, Nobutaka Fujii, Hiroaki Ohno, Shinya Oishi
- Organizer
  第53回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] Design of Fe(II)-chelaing cyclic hexapeptide with bidentate pyridinyl-triazlole groups2016
- Author(s)
  Yuka Kobayashi, Shinya Oishi, Hiroaki Ohno, Nobutaka Fujii
- Organizer
  第53回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] ヒト乳癌細胞に対する新規KSP(kinesin spindle protein)阻害薬の効果2016
- Author(s)
  太田有紀, 土屋聖子, 武永美津子, 角田智志, 大滝正訓, 新美純, 大石真也,　藤井信孝, 渡辺実, 武半優子, 飯利太朗, 松本直樹
- Organizer
  第37回日本臨床薬理学会
- Place of Presentation
  米子コンベンションセンター（鳥取県・米子市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K10074
[Presentation] 長時間作用型PEG化NK3受容体作動薬の創製2016
- Author(s)
  桑井真司、大石真也、三須良介、大野浩章、山村崇、若林嘉浩、岡村裕昭、藤井信孝
- Organizer
  日本薬学会第136回年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] 新規合成KSP(Kinesin spindle protein)阻害剤のヒト乳癌細胞に対する抗腫瘍効果に関する研究2016
- Author(s)
  土屋聖子, 太田有紀, 武永美津子, 大滝正訓, 新美純, 大石真也, 藤井信孝, 松本直樹, 津川浩一郎
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビッグサイト（東京都・江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K10074
[Presentation] Development of Novel CXCR7 Ligands: Selectivity Switch from CXCR4 Antagonists with Cyclic Pentapeptide Scaffold2016
- Author(s)
  Tomoko Kuroyanagi, Shinya Oishi, Tatsuhiko Kubo, Yuka Kobayashi, Haruka Sekiguchi, Ryosuke Misu, Hiroaki Ohno, Nicolas Montpas, Nikolaus Heveker, Nobutaka Fujii
- Organizer
  第8回武田振興財団薬科学シンポジウム
- Place of Presentation
  武田研修センター（大阪府吹田市）
- Year and Date
  2016-01-21
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] Strictamineの全合成研究2016
- Author(s)
  西山大亮、大原礼子、熊谷洋、千葉浩亮、藤井信孝、大石真也、大野浩章
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] MDM2タンパク質の化学合成と天然物の鏡像体化合物群からの医薬品探索への応用2016
- Author(s)
  野口太朗、大石真也、本田香織、近藤恭光、斎藤臣雄、大野浩章、長田裕之、藤井信孝
- Organizer
  第36回有機合成若手セミナー
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] ケモカイン受容体CXCR7 選択的リガンドの構造最適化研究2016
- Author(s)
  関口遼、大石真也、黒柳友子、小林由佳、大野浩章、藤井信孝
- Organizer
  日本ケミカルバイオロジー学会　第11回年会
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] Facile access to the mirror-image library of chiral natural product derivatives: identification of MDM2-p53 interaction inhibitor2016
- Author(s)
  Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
- Organizer
  第8回武田振興財団薬科学シンポジウム
- Place of Presentation
  武田研修センター（大阪府吹田市）
- Year and Date
  2016-01-21
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] Total synthesis of a novel cytotoxic depsipeptide from Okinawan marine cyanobacteria2016
- Author(s)
  Masato Kaneda, Shinya Oishi, Kosuke Sueyoshi, Toshiaki Teruya, Hiroaki Ohno and Nobutaka Fujii
- Organizer
  第8回武田振興財団薬科学シンポジウム
- Place of Presentation
  武田研修センター（大阪府吹田市）
- Year and Date
  2016-01-21
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] 化学合成タンパク質を利用したc-Src SH2ドメイン阻害剤の探索法の開発2016
- Author(s)
  周敬棠、野口太朗、藤井信孝、大野浩章、大石真也
- Organizer
  第66回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] 天然物とその誘導体の鏡像体化合物群の活用を目指した新規スクリーニング法の開発2015
- Author(s)
  野口太朗、大石真也、本田香織、近藤恭光、斎藤臣雄、大野浩章、長田裕之、藤井信孝
- Organizer
  日本ケミカルバイオロジー学会　第10回年会
- Place of Presentation
  東北大学川内キャンパス（宮城県仙台市）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] Development of Novel CXCR7 Ligands by Selectivity Switch from CXCR4 Antagonists with a Cyclic Pentapeptide Scaffold2015
- Author(s)
  Shinya Oishi, Tomoko Kuroyanagi, Tatsuhiko Kubo, Nicolas Montpas, Yasushi Yoshikawa, Ryosuke Misu, Yuka Kobayashi, Hiroaki Ohno, Nikolaus Heveker, Toshio Furuya, and Nobutaka Fujii
- Organizer
  AIMECS2015
- Place of Presentation
  Jeju international convention center（韓国、済州島）
- Year and Date
  2015-10-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] Identification of an MDM2-p53 interaction inhibitor from virtual mirror-image library of chiral natural product derivatives2015
- Author(s)
  Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚市中央公民館（神奈川県平塚市）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] Identification of a novel MDM2-p53 inhibitor using mirror-image-screening technology for chiral natural products2015
- Author(s)
  Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
- Organizer
  SKO symposium
- Place of Presentation
  New Drug Development Center, Seoul University（韓国、ソウル）
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] ケモカイン受容体CXCR7選択的リガンドの構造最適化研究2015
- Author(s)
  黒柳友子，大石真也，小林由佳，関口遼，三須良介，大野浩章，Montpas Nicolas，Heveker Nikolaus，藤井信孝
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター（千葉県幕張市）
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] プロパルギル転位を伴う共役ジインの金触媒三連続環化反応を用いたカルバゾールの合成2015
- Author(s)
  田口将光、時水勇輔、大石真也、藤井信孝、大野浩章
- Organizer
  第45回複素環化学討論会
- Place of Presentation
  早稲田大学（東京都新宿区）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] 天然物とその誘導体の鏡像体化合物群の活用を目指した新規スクリーニング法の開発2015
- Author(s)
  野口太朗、大石真也、本田香織、近藤恭光、斎藤臣雄、大野浩章、長田裕之、藤井信孝
- Organizer
  日本ケミカルバイオロジー学会　第10回年会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] ケモカイン受容体CXCR7選択的リガンドの構造最適化研究2015
- Author(s)
  黒柳友子，大石真也，久保達彦，三須良介，小林由佳，大野浩章，Montpas Nicolas，Heveker Nikolaus，吉川寧，古谷利夫，藤井信孝
- Organizer
  第65回日本薬学会　近畿支部総会・大会
- Place of Presentation
  大阪大谷大学（大阪府羽曳野市）
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] Novel screening approach for drug discovery from virtual mirror-image libaray of natural products2015
- Author(s)
  Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
- Organizer
  Pacifichem 2015
- Place of Presentation
  Hilton Hawaiian Village（米国、ホノルル市）
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] アポモルヒネによるMDM2-p53相互作用の阻害メカニズムの解明2015
- Author(s)
  石場勲之、大石真也、野口太朗、周敬棠、大野浩章、本田香織、近藤恭光、斎藤臣雄、長田裕之、藤井信孝
- Organizer
  第65回日本薬学会近畿支部大会
- Place of Presentation
  大阪大谷大学（大阪府富田林市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] Identification of a novel MDM2-p53 inhibitor using mirror-image-screening technology for chiral natural products2015
- Author(s)
  Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
- Organizer
  SKO symposium
- Place of Presentation
  ソウル国際大学（韓国、ソウル市）
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] キラルな天然有機化合物の鏡像体群をリソースとしたMDM2-p53間相互作用阻害剤の探索2015
- Author(s)
  野口太朗、大石真也、本田香織、近藤恭光、斎藤臣雄、大野浩章、長田裕之、藤井信孝
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター（千葉県幕張市）
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] Investigation of inhibitory mechanism of apomorphine against MDM2-p53 interaction2015
- Author(s)
  Hiroyuki Ishiba, Shinya Oishi, Taro Noguchi, Keito Shu, Hiroaki Ohno, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroyuki Osada, Nobutaka Fujii
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚市中央公民館（神奈川県平塚市）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] MDM2-p53タンパク質間相互作用に対するアポモルフィンの阻害メカニズムの解明2015
- Author(s)
  石場勲之、大石真也、野口太朗、周敬棠、大野浩章、藤井信孝
- Organizer
  創薬懇話会2015 in 徳島
- Place of Presentation
  グランドエクシブ鳴門ザ・ロッジ（徳島県鳴門市）
- Year and Date
  2015-07-01
- Data Source
  KAKENHI-PROJECT-15H04653
[Presentation] 環境調和型NK3受容体拮抗剤の創製研究2015
- Author(s)
  山本昂輝、大石真也、大野浩章、藤井信孝
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター（千葉県幕張市）
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] Novel screening approach for drug discovery from virtual mirror-image library of natural products2015
- Author(s)
  Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
- Organizer
  Pacifichem 2015
- Place of Presentation
  Hilton Hawaiian Village（アメリカ、ホノルル）
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] PEG修飾による長時間作用型NK3受容体作動薬の創製2015
- Author(s)
  桑井真司、大石真也、三須良介、岡崎志穂、山本昂輝、大野浩章、山村崇、若林嘉浩、岡村裕昭、藤井信孝
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター（千葉県幕張市）
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] 共役ジインとピロールを用いた金触媒[4+2]型インドール合成と縮環骨格構築への展開2015
- Author(s)
  松田優佳、直江紗織、大石真也、藤井信孝、大野浩章
- Organizer
  第45回複素環化学討論会
- Place of Presentation
  早稲田大学（東京都新宿区）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15H04654
[Presentation] 化合物アレイを用いた新規MDM2/MDMX-p53阻害剤探索法の開発2013
- Author(s)
  野口太朗、大石真也、久保達彦、大野浩章、近藤恭光、斎藤臣雄、長田裕之、藤井信孝
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] ピリミドベンゾチアジン誘導体の新規合成法の開発と抗HIV剤を指向した構造活性相関研究2012
- Author(s)
  水原司、大石真也、大野浩章、志村和也、松岡雅雄、藤井信孝
- Organizer
  第7回日本ケミカルバイオロジー学会年会
- Place of Presentation
  京都大学（京都府）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] ピリミドベンゾチアジン誘導体の合成法の開発と抗HIV 剤の構造活性相関研究への応用2012
- Author(s)
  水原司、大石真也、大野浩章、志村和也、松岡雅雄、藤井信孝
- Organizer
  第42回複素環化学討論会
- Place of Presentation
  京都テルサ（京都府）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Potent CXCR4 Antagonists Containing Amidine-type Peptide Bond Isosteres2012
- Author(s)
  Kubo T, Inokuchi E, Oishi S, Ohno H, Shimura K, Matsuoka M, Fujii N.
- Organizer
  AIMECS11
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Jaspine B立体異性体の分岐的合成と構造活性相関研究2012
- Author(s)
  宮垣潤、吉光佑二、大石真也、大野浩章、藤井信孝
- Organizer
  第7回日本ケミカルバイオロジー学会年会
- Place of Presentation
  京都大学（京都府）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Efficient synthesis of pyrimido[1,2-c][1,3]benzothiazin-6-imine derivatives and its application to structure-activity relationship study of anti-HIV agents2012
- Author(s)
  Mizuhara T, Oishi S, Ohno H, Shimura K, Matsuoka M, Fujii N.
- Organizer
  第6回武田科学振興財団薬科学シンポジウム
- Place of Presentation
  武田薬品工業研修所（大阪府）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Jaspine Bおよびその誘導体の多様性指向型合成研究2012
- Author(s)
  宮垣潤、吉光佑二、大石真也、藤井信孝、大野浩章
- Organizer
  第42回複素環化学討論会
- Place of Presentation
  京都テルサ（京都府）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Stereoselective divergent synthesis of four diastereomers of pachastrissamine (jaspine B) and their sphingosine kinase inhibitory activities2012
- Author(s)
  吉光佑二、宮垣潤、大石真也、藤井信孝、大野浩章
- Organizer
  ISMC2012
- Place of Presentation
  ベルリン（ドイツ）
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] Jaspine Bおよびその誘導体の多様性指向型合成2012
- Author(s)
  宮垣潤、吉光佑二、大石真也、藤井信孝、大野浩章
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学（北海道）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Stereoselective divergent synthesis of four diastereomers of pachastrissamine (jaspine B) and their sphingosine kinase inhibitory activities2012
- Author(s)
  吉光佑二、宮垣潤、大石真也、藤井信孝、大野浩章
- Organizer
  ISMC2012
- Place of Presentation
  ベルリン（ドイツ）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Synthesis and anti-HIV activity of pyrimido[1,2-c][1,3]benzothiazin-6-imine derivatives2012
- Author(s)
  Mizuhara T, Oishi S, Ohno H, Shimura K, Matsuoka M, Fujii N.
- Organizer
  IKCOC-12
- Place of Presentation
  リーがロイヤルホテル京都（京都府）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Synthesis and structure-activity relationship study of pyrimido[1,2-c][1,3]benzothiazin-6-imine derivatives for development of anti-HIV agents2012
- Author(s)
  水原司、大石真也、大野浩章、志村和也、松岡雅雄、藤井信孝
- Organizer
  The 7th SKO Joint Symposium for Young Scientists
- Place of Presentation
  京都大学（京都府）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] アザインドール骨格またはフェニルアゾール骨格を有する新規プロテインキナーゼCK2阻害剤の開発研究2012
- Author(s)
  侯増燁、大石真也、武井義則、安江美里、三須良介、鈴木大和、村田克美、北浦和夫、平澤明、辻本豪三、大野浩章、藤井信孝、仲西功、中村真也、呉竜英、木下誉富
- Organizer
  第10回次世代を担う有機化学シンポジウム
- Place of Presentation
  大阪大学銀杏会館（大阪府）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Jaspine Bおよびその誘導体の多様性指向型合成研究2012
- Author(s)
  宮垣潤、吉光佑二、大石真也、藤井信孝、大野浩章
- Organizer
  第42回複素環化学討論会
- Place of Presentation
  京都テルサ（京都府）
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] Efficient Synthesis of Highly Functionalized Dihydropyrazoles via Gold-Catalyzed Three-Component Annulation2012
- Author(s)
  Suzuki Y, Oishi S, Fujii N, Ohno H.
- Organizer
  AIMECS11
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Efficient Synthesis of Pyrimido[1,2-c]benzothiazin-6-imine and Related Tricyclic Heterocycles by Cu(II)-mediated C-H Functionalization and Aromatic Nucleophilic Substitution2011
- Author(s)
  Mizuhara T, Oishi S, Fujii N, Ohno H.
- Organizer
  AIMECS11
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Synthesis and Biological Evaluation of Novel CXCR4 Antagonists Containing Amidine-type Peptide Bond Isosteres2011
- Author(s)
  Inokuchi E, Oishi S, Kubo T, Ohno H, Shimura K, Matsuoka M, Fujii N.
- Organizer
  22nd American Peptide Symposium
- Place of Presentation
  San Diego（United States of America）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Structure-activity Relationship Study on a CXCR4 Antagonist FC131 Using Alkene-type Dipeptide Isosteres2011
- Author(s)
  Kobayashi K, Oishi S, Hayashi R, Tomita K, Kubo T, Tanahara N, Ohno H, Naito T, Matsuoka M, Fujii N.
- Organizer
  22nd American Peptide Symposium
- Place of Presentation
  San Diego（United States of America）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] DIVERSITY-ORIENTED SYNTHESIS OF PYRIMIDO[1,2-c][1,3]BENZOTHIAZIN-6-IMINE AND THE RELATED TRICYCLIC HETEROCYCLES2011
- Author(s)
  Mizuhara T, Oishi S, Ohno H, Fujii N
- Organizer
  Nature Chemical Biology Symposium 2011: Cancer Chemical Biology
- Place of Presentation
  Boston（United States of America）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] INTERNALIZATION OF CXC CHEMOKINE RECEPTOR 4 (CXCR4) INDUCED BY POLYPHEMUSIN II-DERIVED ANTAGONIST PEPTIDES2011
- Author(s)
  Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Yano Y, Matsuzaki K, Nakase I, Futaki S, Fujii N.
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Jaspine Bおよびその誘導体の多様性指向型合成2011
- Author(s)
  宮垣潤、吉光佑二、大石真也、藤井信孝、大野浩章
- Organizer
  第28回有機合成化学セミナー
- Place of Presentation
  滝の湯（山形県）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] アミジン型ペプチド結合等価体の合成と応用2011
- Author(s)
  井ノ口恵利子、山田愛、大石真也、久保達彦、大野浩章、保住健太郎、野水基義、志村和也、松岡雅雄、藤井信孝
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京工業大学大岡山キャンパス（東京都）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] アルケン型及びアミジン型ジペプチドイソスターの合成とCXCR4拮抗剤の構造活性相関研究への応用2011
- Author(s)
  小林数也、大石真也、井ノ口恵利子、林亮子、富田健嗣、久保達彦、棚原憲子、大野浩章、藤井信孝、吉川寧、古谷利夫、志村和也、松岡雅雄
- Organizer
  第37回反応と合成の進歩シンポジウム
- Place of Presentation
  あわぎんホール（徳島県）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Gold-catalyzed three-component annulation: an efficient synthesis of 1,2,3,5-tetrasubstituted dihydropyrazoles from alkynes, aldehydes, and hydrazines2011
- Author(s)
  Suzuki Y, Oishi S, Fujii N, Ohno H.
- Organizer
  242nd American Chemical Society National Meeting & Exposition
- Place of Presentation
  Denver（United States of America）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 金触媒による三成分環形成反応を用いた多置換ジヒドロピラゾールの効率的合成法の開発2011
- Author(s)
  鈴木大和，大石真也，藤井信孝，大野浩章
- Organizer
  第37回反応と合成の進歩シンポジウム
- Place of Presentation
  あわぎんホール（徳島県）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 縮環インドール構造を有する新規Eg5阻害剤の開発2011
- Author(s)
  竹内智起、大石真也、渡部敏明、大野浩章、浅田直也、北浦和夫、澤田潤一、浅井章良、藤井信孝
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京工業大学大岡山キャンパス（東京都）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Jaspine Bおよびその誘導体の立体分岐合成と構造活性相関研究2011
- Author(s)
  吉光佑二、大石真也、宮垣　潤、井貫晋輔、藤井信孝、大野浩章
- Organizer
  第7回次世代を担う有機化学シンポジウム
- Place of Presentation
  日本薬学会長井記念ホール（東京都）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] DEVELOPMENT AND APPLICATION OF FLUORESCENT PROBES FOR MONITORING CXCR4 RECEPTOR INTERNALIZATION2011
- Author(s)
  Oishi S, Masuda R, Tanahara N, Ohno H, Yano Y, Matsuzaki K, Hirasawa A, Tsujimoto G, Fujii N.
- Organizer
  Nature Chemical Biology Symposium 2011: Cancer Chemical Biology
- Place of Presentation
  Boston（United States of America）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Synthesis and Application of Fluorescent SDF-1 Derivatives2011
- Author(s)
  Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Yano Y, Matsuzaki K, Fujii N.
- Organizer
  22nd American Peptide Symposium
- Place of Presentation
  San Diego（United States of America）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Development of a Novel Class of ATP-competitive Kinesin Spindle Protein Inhibitors2011
- Author(s)
  Oishi S, Takeuchi T, Watanabe T, Ohno H, Sawada J, Matsuno M, Asai A, Asada N, Kitaura K, Fujii N.
- Organizer
  AIMECS11
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 縮環インドール構造を有する新規Eg5阻害剤の開発2010
- Author(s)
  竹内智起、大石真也、大野浩章、藤井信孝, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] ペプチドミメティクスの利用による新規GPR54アゴニストの創製2009
- Author(s)
  説田章平、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第41回若手ペプチド夏の勉強会
- Place of Presentation
  東京
- Year and Date
  2009-08-03
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] アルケン型ジペプチドイソスターの合成とケモカイン受容体CXCR4拮抗剤の構造活性相関研究への応用2009
- Author(s)
  林亮子、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] Efficient Synthesis of Trifluoromethyl and Related Trisubstituted Alkene Dipeptide Isosteres by Pd-Catalyzed Carbonylation of Amino Acid-Derived Allylic Carbonates2009
- Author(s)
  Inokuchi E, Oishi S, Ohno H, Fujii N, et al.
- Organizer
  8th Australian Peptide Conference
- Place of Presentation
  Queensland Australia
- Year and Date
  2009-10-12
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] 固相上におけるペプチド鎖へのDTPAの新規標識法の開発2009
- Author(s)
  増田亮、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] アルケン型ジペプチドイソスターの合成とケモカイン受容体CXCR4拮抗剤の構造活性相関研究への応用2009
- Author(s)
  林亮子、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第59回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] カルバゾール骨格を有する新規Eg5阻害剤のデザインと合成2009
- Author(s)
  渡部敏明、大石真也、大野浩章、藤井信孝, 他
- Organizer
  日本ケミカルバイオロジー研究会第4回年会
- Place of Presentation
  神戸
- Year and Date
  2009-05-19
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] ケモカイン受容体CXCR4選択的蛍光プローブを活用した新規化合物評価系の構築2009
- Author(s)
  棚原憲子、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第59回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] 有機銅-亜鉛複合試薬を用いたトリフルオロメチルアルケンジペプチドイソスターの新規合成法の開発2009
- Author(s)
  小林数也、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第35回反応と合成の進歩シンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-16
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] ケモカイン受容体CXCR4選択的蛍光プローブを活用した化合物評価系の構築2009
- Author(s)
  棚原憲子、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] アルケン型ジペプチドイソスターの合成とケモカイン受容体CXCR4拮抗剤の構造活性相関研究への応用2009
- Author(s)
  林亮子、大石真也、大野浩章、藤井信孝, 他
- Organizer
  日本ケミカルバイオロジー研究会第4回年会
- Place of Presentation
  神戸
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] ケモカイン受容体CXCR4選択的蛍光プローブを活用した新規化合物評価系の構築2009
- Author(s)
  棚原憲子、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第59回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] アルケン型ジペプチドイソスターの合成とケモカイン受容体CXCR4拮抗剤の構造活性相関研究への応用2009
- Author(s)
  林亮子、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第59回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] ペプチドミメティクスの利用による新規GPR54アゴニストの創製2009
- Author(s)
  説田章平、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第6回GPCR研究会
- Place of Presentation
  東京
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] ペプチドミメティクスの利用による新規GPR54アゴニストの創製2009
- Author(s)
  説田章平、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第41回若手ペプチド夏の勉強会
- Place of Presentation
  東京
- Year and Date
  2009-08-03
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] ペプチドミメティクスの利用による新規GPR54アゴニストの創製2009
- Author(s)
  説田章平、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第6回GPCR研究会
- Place of Presentation
  東京
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] Synthesis and Application of Novel Fluorescent-Labeled CXCR4 Antagonists2009
- Author(s)
  増田亮、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第10回文部科学省特定領域研究「がん」5領域若手研究者ワークショップ
- Place of Presentation
  蓼科
- Year and Date
  2009-09-02
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] 固相上におけるペプチド鎖へのDTPAの新規標識法の開発2009
- Author(s)
  増田亮、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] アルケン型ジペプチドイソスターの合成とケモカイン受容体CXCR4拮抗剤の構造活性相関研究への応用2009
- Author(s)
  林亮子、大石真也、大野浩章、藤井信孝, 他
- Organizer
  日本ケミカルバイオロジー研究会第4回年会
- Place of Presentation
  神戸
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] ケモカイン受容体CXCR4選択的蛍光プローブを活用した化合物評価系の構築2009
- Author(s)
  棚原憲子、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] Synthesis and Application of Novel Fluorescent-Labeled CXCR4 Antagonists2009
- Author(s)
  増田亮、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第10回文部科学省特定領域研究「がん」5領域若手研究者ワークショップ
- Place of Presentation
  蓼科
- Year and Date
  2009-09-02
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] アルケン型ジペプチドイソスターの合成とケモカイン受容体CXCR4拮抗剤の構造活性相関研究への応用2009
- Author(s)
  林亮子、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] 縮環インドール構造を有する新規Eg5阻害剤の開発2009
- Author(s)
  竹内智起、大石真也、大野浩章、藤井信孝, 他
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] CXCR4受容体アンタゴニストの蛍光標識体の創製と応用2008
- Author(s)
  増田亮、大石真也、藤井信孝、他
- Organizer
  日本ケミカルバイオロジー研究会第3回年会
- Place of Presentation
  東京
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] 多様なジペフチドイゾースターの分岐的合成とGPR54アゴニストへの応用2008
- Author(s)
  富田健嗣、大石真也、藤井信孝、他
- Organizer
  第27回メディシナルケミストリーシンポジウム
- Place of Presentation
  大阪
- Year and Date
  2008-11-26
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] Development of novel non-peptide CXCR4 antagonists based on cyclic peptide structure2008
- Author(s)
  Oishi S., Katoh M., Ueda S., Inuki S., Ohno H., Barry Evans, Zi-xuan Wang, Stephen C. Peiper, Fujii N.
- Organizer
  3rd Annual Meeting of Japan Chemical Biology Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of Novel Pseudopeptide GPR54 Agonists with High Tolerance against MMP-Mediaed Digestion2008
- Author(s)
  Kenji Tomita, Shinya Oishi,Nobutaka Fujii, 他
- Organizer
  XXth International Symposium on Medicinal Chemistry
- Place of Presentation
  ウイーン
- Year and Date
  2008-09-01
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] 新規ファルマコフォアを有するケモカインレセプターCXCR4アンタゴニストの構造活性相関研究2008
- Author(s)
  田中智博、大石真也、藤井信孝、他
- Organizer
  日本ケミカルバイオロジー研究会第3回年会
- Place of Presentation
  東京
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] 化合物の提供と新規フラグメント化合物群の創製による化合物ライブラリー充実への貢献-ドラッグライク構造を有する多置換型複素環の効率的合成法の開発-2008
- Author(s)
  藤井信孝, et al.
- Organizer
  ターゲットターンパク研究プログラム第1回公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-02-12
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] CXCR4 Antagonists : Relevance to Cancer Chemotherapy2008
- Author(s)
  Nobutaka Fujii, Shinya Oishi
- Organizer
  XXth International Symposium on Medicinal Chemistry
- Place of Presentation
  ウイーン
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] マトリックスメタロプロテアーゼ耐性GPR54アゴニストの開発2008
- Author(s)
  富田健嗣、大石真也、藤井信孝、他
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] Novel labeling protocol for cell-membrane proteins by tag-probe method-2008
- Author(s)
  Yano Y., Yano A., Oishi S., Sugimoto Y., Tsujimoto G., Fujii N., Matsuszaki K.
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and application of fluorescent CXCR4 antagonist2008
- Author(s)
  Masuda R., Oishi S., Ueda S., Evans B., Peiper SC, Hirasawa A., Tsujimoto G., Ohno H., Fujii N.
- Organizer
  3rd Annual Meeting of Japan Chemical Biology Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Chemical Virologyを基盤とする新興・再興ウイルス侵入阻害剤の開発研究2008
- Author(s)
  藤井信孝
- Organizer
  第4回ケミカルバイオロジーシンポジウム-化学-生物融合領域創成の軌跡-
- Place of Presentation
  熱海
- Year and Date
  2008-02-07
- Data Source
  KAKENHI-PROJECT-18060020
[Presentation] Chemical Virologyを基盤とする新興・再興ウイルス侵入阻害剤の開発研究2008
- Author(s)
  藤井信孝
- Organizer
  第4回ケミカルバイオロジーシンボジウムー化学-生物融合領域創成の軌跡-
- Place of Presentation
  熱海
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 求核的CF3化反応による立体選択的トリフルオロメチルアルケン型ジペプチドイソスターの合成研究2008
- Author(s)
  小林数也、大石真也、藤井信孝、他
- Organizer
  第58回日本薬学会近畿支部総会
- Place of Presentation
  神戸
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] Design and synthesis of anti-HIV peptides having helix-inducible motifs2008
- Author(s)
  Watanabe K., Oishi S., Itoh S., Tanaka M., Hishikawa H., Watabe T., Izumi K., Sakagami Y., Kodama E., Matsuoka M., Ohno H., Fujii N.
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] ジペプチドイソスターの分岐型合成による酵素耐性GPR54アゴニストの創出2008
- Author(s)
  富田健嗣、大石真也、藤井信孝、他
- Organizer
  第34回反応と合成の進歩シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-11-04
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] Chemical Virologyを基盤とする新興・再興ウイルス侵入阻害剤の開発研究2008
- Author(s)
  藤井信孝
- Organizer
  第4回ケミカルバイオロジーシンポジウム-化学-生物融合領域創成の軌跡-
- Place of Presentation
  熱海
- Year and Date
  2008-02-07
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Model development for virtual screening of CYP-interactive compounds using CCA spatial model2008
- Author(s)
  Ogawa T., Minowa Y., Adachi T., Feng C, Niijima S., Oishi S., Fujii N., Okuno Y.
- Organizer
  5th Seminars on Biomedical Researches
- Place of Presentation
  Osaka
- Year and Date
  2008-02-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] X-ray crystal structure analysis of 6-helical bundle structure of T-20 (Fuzeon) -resistant HIV mutants2008
- Author(s)
  Watabe T., Oishi S., Nishikawa H., Watanabe K., Nakano H., Nakatsu T., Ohno H., Katoh H., Kodama E., Matsuoka M., Fujii N.
- Organizer
  88th Spring meeting of the chemical society of Japan
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 多様なジペプチドイソスターの分岐的合成と応用2008
- Author(s)
  富田健嗣、大石真也、藤井信孝、他
- Organizer
  第28回有機合成若手セミナー
- Place of Presentation
  大阪
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] ケモカイン受容体CXCR4に対する蛍光標識リカンドの創製と応用2008
- Author(s)
  増田亮、大石真也、藤井信孝、他
- Organizer
  第58回日本薬学会近畿支部総会
- Place of Presentation
  神戸
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] 求核的CF3化反応による立体選択的トリフルオロメチルアルケン型ジペプチドイソスターの合成研究2008
- Author(s)
  小林数也、大石真也、藤井信孝、他
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] 環状ペプチドをリードとする非ペプチド性CXCR4拮抗剤の開発2008
- Author(s)
  大石真也、藤井信孝、他
- Organizer
  日本ケミカルバイオロジー研究会第3回年会
- Place of Presentation
  東京
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] 求核的CF3化反応による立体選択的トリフルオロメチルアルケン型ジペプチドイソスターの合成研究2008
- Author(s)
  小林数也、大石真也、藤井信孝、他
- Organizer
  第58回日本薬学会近畿支部総会
- Place of Presentation
  神戸
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] Structure-activity relathionship on pyrazine-based CK2 inhibitors2008
- Author(s)
  Suzuki Y., Cluzeau J., Oishi S., Ohno H., Fujii N., Hara T., Hirasawa A., Tsujimoto G.
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Establishment of bioevaluation technology for drug discovery for GPCR -novel labeling protocol for cell-membrane proteins by tag-probe method-2008
- Author(s)
  Yano Y., Oishi S., Sugimoto Y., Tsujimoto G., Fujii N., Matsuzaki K.
- Organizer
  The 1st Symposium on Target Protein Research Program
- Place of Presentation
  Tokyo
- Year and Date
  2008-02-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of anti viral agents of emerging and re-emerging viruses based on chemical virology2008
- Author(s)
  Fujii N.
- Organizer
  The 4th Chemical Biology Symposium
- Place of Presentation
  Atami
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 求核的CF3化反応による立体選択的トリフルオロメチルアルケン型ジペプチドイソスターの合成研究2008
- Author(s)
  小林数也、大石真也、藤井信孝、他
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] CXCR4受容体アンタゴニストの蛍光標識体の創製と応用2008
- Author(s)
  増田亮、大石真也、藤井信孝、他
- Organizer
  第41回若手ペプチド夏の勉強会
- Place of Presentation
  京都
- Year and Date
  2008-08-04
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] 多様なジペプチドイソスターの分岐的合成と応用2008
- Author(s)
  富田健嗣、大石真也、藤井信孝、他
- Organizer
  第28回有機合成若手セミナー
- Place of Presentation
  大阪
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] CXCR4 Antagonists: Relevance to Cancer Chemotherapy2008
- Author(s)
  Nobutaka Fujii, Shinya Oishi
- Organizer
  XXth International Symposium on Medicinal Chemistry
- Place of Presentation
  ウイーン
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] Contribution to chemical library by preparation of novel fragment compound -efficient synthesis of multi-substituted heterocycles having drug-like strucure-2008
- Author(s)
  Fujii N., Ohno H., Oishi S., Takemoto Y., Takasu K, Yasui Y., Tomioka K., Yamada K., Yamamoto Y.
- Organizer
  The 1st Symposium on Target Protein Research Program
- Place of Presentation
  Tokyo
- Year and Date
  2008-02-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 化合物の提供と新規フラグメント化合物群の創製による化合物ライブラリー充実への貢献-ドラッグライク構造を有する多置換型複素環の効率的合成法の開発-2008
- Author(s)
  藤井信孝, et al.
- Organizer
  ターゲットタンパク研究プログラム第1回公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-02-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and application of Z-alkene and E-fluoroalkene dipeptide isosteres as cis-amide bond equivalents2008
- Author(s)
  Tomita K, Narumi T., Niida A., Oishi S., Ohno H., Fujii N.
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] ジペプチドイソスターの分岐型合成による酵素耐性GPR54アゴニストの創出2008
- Author(s)
  富田健嗣、大石真也、藤井信孝、他
- Organizer
  第34回反応と合成の進歩シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-11-04
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] 環状ペンタペプチド骨格を有するCXCR4アンタゴニスドの構造活性相関研究 : 新規ファルマコフォアの同定2008
- Author(s)
  田中智博、藤井信孝、他
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] Synthesis of nitrogen heterocycles by palladium-catalyzed sp3 C-H activation.2008
- Author(s)
  Toshiaki Watanabe, Shinya Oishi, Nobutaka Fujii, Hiroaki Ohno
- Organizer
  The 9th Youngnam-Kinki Joint Symposium on Organometallic Chemistry
- Place of Presentation
  Kyoto
- Year and Date
  2008-01-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] CXCR4受容体アンタゴニストの蛍光標識体の創製と応用2008
- Author(s)
  増田亮、大石真也、藤井信孝、他
- Organizer
  第41回若手ペプチド夏の勉強会
- Place of Presentation
  京都
- Year and Date
  2008-08-04
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] Development of screening system for anti-cancer lead compounds -for HIF-1-targeting agents -2008
- Author(s)
  Hattori A., Yagura T., Nishimura S., Oishi S., Fujii N., Kakeya H.
- Organizer
  The 1st Symposium on Target Protein Research Program
- Place of Presentation
  Tokyo
- Year and Date
  2008-02-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Selection of Chemicals for General Library2008
- Author(s)
  Yasuno K., Kojima H., Okabe T., Oishi S., Fujii N., Nagano T. Furuya T.
- Organizer
  The 1st Symposium on Target Protein Research Program
- Place of Presentation
  Tokyo
- Year and Date
  2008-02-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 環状ペンタペプチド骨格を有するCXCR4アンタゴニストの構造活性相関研究 : 新規ファルマコフォアの同定2008
- Author(s)
  田中智博、藤井信孝、他
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] Development of novel in silico technology based on compounds-protein interactions2008
- Author(s)
  Ogawa T., Kitajima M., Minowa Y., Matsuda H., Fujii N., Okuno Y.
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 多様なジペプチドイソスターの分岐的合成とGPR54アゴニストへの応用2008
- Author(s)
  富田健嗣、大石真也、藤井信孝、他
- Organizer
  第27回メディシナルケミストリーシンポジウム
- Place of Presentation
  大阪
- Year and Date
  2008-11-26
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] 環状ペプチドをリードとする非ペプチド性CXCR4拮抗剤の開発2008
- Author(s)
  大石真也、藤井信孝、他
- Organizer
  日本ケミカルバイオロジー研究会第3回年会
- Place of Presentation
  東京
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] 新規ファルマコフォアを有するケモカインレセプターCXCR4アンタゴニストの構造活性相関研究2008
- Author(s)
  田中智博、大石真也、藤井信孝、他
- Organizer
  日本ケミカルバイオロジー研究会第3回年会
- Place of Presentation
  東京
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] Development of Novel Pseudopeptide GPR54 Agonists withHigh Tolerance against MMP-Mediaed Digestion2008
- Author(s)
  Kenji Tomita, Shinya Oishi, Nobutaka Fujii, 他
- Organizer
  XXth International Symposium on Medicinal Chemistry
- Place of Presentation
  ウイーン
- Year and Date
  2008-09-01
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] Synthesis and application of fluorescent CXCR4 antagonist2008
- Author(s)
  Masuda R., Oishi S., Ueda S., Barry Evans, Stephen C. Peiper, Hirasawa A., Tsujimoto G., Ohno H., Fujii N.
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Stereoselective synthesis of trifluoromethylalkene dipeptide isosteres by nucliophilic CF3-introduction2008
- Author(s)
  Kobayashi K., Narumi T., Inokuchi E., Tomita K., Oishi S., Ohno H., Fujii N.
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] ケモカイン受容体CXCR4に対する蛍光標識リガンドの創製と応用2008
- Author(s)
  増田亮、大石真也、藤井信孝、他
- Organizer
  第58回日本薬学会近畿支部総会
- Place of Presentation
  神戸
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] Structure-activity relathionship on pyrazine-based CK2 inhibitors2008
- Author(s)
  Suzuki Y., Jerome Cluzeau, Hara T., Hirasawa A., Tsujimoto G., Oishi S., Ohno H., Fujii N.
- Organizer
  3rd Annual Meeting of Japan Chemical Biology Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] マトリックスメタロプロテアーゼ耐性GPR54アゴニストの開発2008
- Author(s)
  富田健嗣、大石真也、藤井信孝、他
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20015021
[Presentation] Structure-activity relationship on CXCR4 antagonists having novel pharmacophores2008
- Author(s)
  Tanaka T., Nomura W., Tsutsumi H., Tabe Y., Ohhashi N., Itoya K., Oishi S., Fujii N., Evans B., Wang Z., Peiper SC, Tamamura H.
- Organizer
  3rd Annual Meeting of Japan Chemical Biology Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] CXCR4受容体アンタゴニストの蛍光標識体の創製と応用2008
- Author(s)
  増田亮、大石真也、藤井信孝、他
- Organizer
  日本ケミカルバイオロジー研究会第3回年会
- Place of Presentation
  東京
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20057011
[Presentation] Structure-activity relationship study on GPR54 agonist as novel anti-metastatic agent.2007
- Author(s)
  Tomita K., Oishi S., Ohno H., Akamatsu M., Fujii N.
- Organizer
  First JCA-AACR Special Joint Conference : The Latest Advances in Lung Cancer Research : From Basic Science to Therapeutics
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of fluoroalkene isosteres using intramolecular redox reaction by N-heterocyclic carbene2007
- Author(s)
  Yamaki Y., Shigenaga A., Tomita K., Narumi T., Fujii N., Otaka A.
- Organizer
  The 127th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From amino acids to peptide isosteres: Implication to genome-lead drug discovery.2007
- Author(s)
  Fujii N., Oishi S., Narumi T., Tomita K., Ohno H.
- Organizer
  2nd. World Congress of Pharmacy and Pharmaceutical Sciences
- Place of Presentation
  Beijing
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and application of fluorescent CXCR4 antagonist2007
- Author(s)
  Masuda R., Oishi S., Ueda S., Gotoh S., Ohno H., Evans B., Peiper SC, Hirasawa A., Tsujimoto G., Kodama E., Matsuoka M., Fujii N.
- Organizer
  44th Japanese Peptide Symposium
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] CXCR4 antagonists : Relevance to small cell lung cancer chemotherapy.2007
- Author(s)
  Fujii N., Oishi S., Ueda S.
- Organizer
  First JCA-AACR Special Joint Conference : The Latest Advances in Lung Cancer Research : From Basic Science to Therapeutics
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Anti-HIV activity of water-soluble analogue of C29, SC29EK2007
- Author(s)
  Naitoh T., Izumi K., Kodama E., Oishi S., Fujii N., Matsuoka M.
- Organizer
  21st Annual meeting of the Japan Society for AIDS research
- Place of Presentation
  Hiroshima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Stereoselective synthesis of peptidomimetics based on acid-catalyzed ring-opening of □-aziridinyl-□, □-enoates.2007
- Author(s)
  Tamamura H., Tanaka T., Tsutsumi H., Nemoto K., Mizokami S., Ohashi N., Oishi S., Fujii N.
- Organizer
  20th American Peptide Symposium
- Place of Presentation
  Montreal
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] CXCR4 Antagonists; Relevance to Cancer Chemotherapy2007
- Author(s)
  Fujii N.
- Organizer
  6th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Istanbul
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-18659027
[Presentation] One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling2007
- Author(s)
  Watanabe T., Inuki S., Ueda S., Oishi S., Ohno H., Fujii N.
- Organizer
  6th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Istanbul
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From knowledge to controlling : implications of peptide-lead drug templates for genome-lead discovery.2007
- Author(s)
  Nobutaka Fujii, Hiroaki Ohno, Shinya Oishi
- Organizer
  RIKEN International Symposium on Chemical Biology
- Place of Presentation
  Hakone
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From amino acids to peptide isosteres: Implication to genome-lead drug discovery2007
- Author(s)
  Nobutaka Fujii, et al.
- Organizer
  2nd. World Congress of Pharmacy and Pharmaceutical Sciences
- Place of Presentation
  北京
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Construction of 2-(aminomethyl)indole motif by Cu-catalyzed multi-component reaction.2007
- Author(s)
  Ohta Y., Oishi S., Fujii N., Ohno H.
- Organizer
  234th ACS meeting & exposition
- Place of Presentation
  Boston
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Plasma concentration of metastins in pancreatic cancer patients2007
- Author(s)
  Katagiri F., Nagai K., Kida M., Tomita K., Oishi S., Takeyama M., Doi R., Fujii N.
- Organizer
  2nd annual meeding of Japan Chemical Biology Society
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of synthetic methodology for fused aromatic compounds by consecutive bond formations2007
- Author(s)
  Ohno H., Ohta Y., Oishi S., Fujii N., Iuchi M., Tanaka T.
- Organizer
  The 33rd Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Nagasaki
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Pd-Catalyzed carbonylation of CF3-containing allylic carbonate : application to the synthesis of (Z)-trifluoromethylalkene dipeptide isosteres.2007
- Author(s)
  Inokuchi E., Narumi T., Tomita K., Niida A., Kobayashi K., Oishi S., Ohno H., Fujii N.
- Organizer
  14th IUPAC Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
- Place of Presentation
  Nara
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 情報から制御へ : ゲノム情報収斂型創薬科学2007
- Author(s)
  藤井信孝
- Organizer
  21C0E公開シンポジウム
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of a novel fusion inhibitor against T-20-resistant HIV-1.2007
- Author(s)
  Oishi S., Ito S., Nishikawa H., Tanaka M., Ohno H., Otaka A., Izumi K., Kodama E., Matsuoka M., Fujii N.
- Organizer
  20th American Peptide Symposium
- Place of Presentation
  Montreal
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of fusion inhibitors against feline immunodeficiency virus (FIV)2007
- Author(s)
  Nishikawa H., Kodera Y., Tanaka M., Mizukoshi F., Tsujimoto H., Kodama E., Matsuoka M., Oishi S., Ohno H., Fujii N.
- Organizer
  2nd annual meeding of Japan Chemical Biology Society
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of trifluoroalkene dipeptide isosteres and the related compounds using paradium-catalyzed carbonylation2007
- Author(s)
  Inokuchi E., Narumi T., Niida A., Tomita K, Oishi S., Ohno H., Fujii N.
- Organizer
  27th Seminars on Organic Synthesis for Young Scientists
- Place of Presentation
  Kyoto
- Year and Date
  2007-11-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From knowledge to controlling : implications of peptide-lead drug templates for genome-lead discovery2007
- Author(s)
  Nobutaka Fujii, et al.
- Organizer
  RIKEN International Symposium on Chemical Biology
- Place of Presentation
  箱根
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of novel FIV membrane fusion inhibitors.2007
- Author(s)
  Nishikawa H., Kodera Y., Oishi S., Tanaka M., Tochikura T., Kajiwara K., Ohno H., Mizukoshi F., Tsujimoto H., Kodama E., Matsuoka M., Fujii N.
- Organizer
  Virus Molecular Interactions : Therapeutic Targets
- Place of Presentation
  Oxford
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 98. CXCE4 antagonists : relevance to cancer chemotherapy2007
- Author(s)
  Kobutaka Fujii
- Organizer
  6th AFMC IEternational Medicinal Chemistry Symposium
- Place of Presentation
  イスタンブール
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] CXCR4 antagonists ; relevance to cancer chemotherapy.2007
- Author(s)
  Fujii N.
- Organizer
  6th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Istanbul
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] CXCR4 antagonists; relevance to cancer chemotherapy2007
- Author(s)
  Nobutaka Fujii
- Organizer
  6th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  イスタンブール
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and in vivo evaluation of 18F labeled fluorobenzoyl pentapeptide ([18F]TOM80) as a PET imaging agent for GPR54.2007
- Author(s)
  T. Fuchigami, N. Harada, H. Tsukada, M. Ogawa, H. Yamaguchi, H. Raku, K. Tomita, S. Ohishi, N. Fujii, Y. Magata
- Organizer
  Seventh Japan-China Joint Semiinar on Radiopharmaceutical Chemistry
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and application of (Z)-alkene- and (E)-fluoroalkene-dipeptide isosteres as cis-amide equivalents.2007
- Author(s)
  Tomita K., Narumi T., Niida A., Oishi S., Ohno H., Fujii N.
- Organizer
  20th American Peptide Symposium
- Place of Presentation
  Montreal
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of bicyclic heterocycles by paradium-catalyzed domino cyclizations of propargyl bromide2007
- Author(s)
  Okano A., Ohno H., Fujii N., Kosaka S., Ohhata M., Ishihara K., Tanaka T. Tsukamoto K.
- Organizer
  The 33rd Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Nagasaki
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of trifluoroalkene dipeptide isosteres and the related compounds using paradium-catalyzed carbonylation2007
- Author(s)
  Inokuchi E., Narumi T., Niida A., Oishi S., Ohno H., Fujii N.
- Organizer
  The 33rd Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Nagasaki
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From information to controls : Drug discovery based on genomeinformation2007
- Author(s)
  Fujii N.
- Organizer
  21COE symposium
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Design and synthesis of anti-HIV peptides having helix-inducible motifs2007
- Author(s)
  Watanabe K., Itoh S., Nishikawa H., Tanaka M., Oishi S., Ohno H., Izumi K., Kodama E., Matsuoka M., Fujii N.
- Organizer
  44th Japanese Peptide Symposium
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and structure-activity relationship on cystein derivatives having Eg5 inhibiory activity2007
- Author(s)
  Ogo N., Oishi S., Matsuno K., Sawada J., Fujii N., Asai A.
- Organizer
  The 26th Symposium on Medicinal Chemistry
- Place of Presentation
  Sagamihara
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of fluoroalkenes of organometal-mediated C-F bond cleavage : application of stereoselective synthesis of multifunctionalized fluoroalkene dipeptide isosteres2007
- Author(s)
  Narumi T., Tomita K., Inokuchi E., Kobayashi K., Oishi S., Ohno H., Fujii N.
- Organizer
  The 57th Kinki Regional Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Osaka
- Year and Date
  2007-10-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and application of carbazoles by palladium-catalyzed tandem N-arylation and oxidative C-H activation2007
- Author(s)
  Watanabe T., Ueda S., Oishi S., Fujii N., Ohno H.
- Organizer
  Eighth Tetrahedron Symposium
- Place of Presentation
  Berlin
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of novel CXCR4 antagonist having an indole scaffold2007
- Author(s)
  Katoh M., Ueda S., Inuki S., Oishi S., Ohno H., Evans B., Wang Z., Peiper SC, Fujii N.
- Organizer
  The 26th Symposium on Medicinal Chemistry
- Place of Presentation
  Sagamihara
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] CXCR4 Antagonists; Relevance to Cancer Chemotherapy.2007
- Author(s)
  Nobutaka Fujii
- Organizer
  6th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Istanbul
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-18015027
[Presentation] Prediction of drugcytochrome P450 interaction using chemical-biological correlation space model.2007
- Author(s)
  Teppei Ogawa, Yosuke Minowa, Tetsuya Adachi, Chunlai Fen, Satoshi Niijima, Shinya Oishi, Nobutaka Fujii, Yasushi Okuno
- Organizer
  Annual meeding of CBI society
- Place of Presentation
  Hiroshima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of fusion inhibitors based on resistant mutation against T-202007
- Author(s)
  Izumi K., Kodama E., Shimura K., Oishi S., Fujii N., Matsuoka M.
- Organizer
  21st Annual meeting of the Japan Society for AIDS research
- Place of Presentation
  Hiroshima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Palladium-catalyzed synthesis of carbazole by tandem N-arylation and C-H activation.2007
- Author(s)
  Watanabe T., Ueda S., Oishi S., Fujii N., Ohno H.
- Organizer
  The 5th Symposium on Organic Chemistry - The Next Generation
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Stereoselective synthesi of (Z)-trifluoromethylalkene dipeptide isosteres2007
- Author(s)
  Inokuchi E., Narumi T., Niida A., Kobayashi K., Oishi S., Ohno H., Fujii N.
- Organizer
  The 127th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From Amino Acids to Peptide Isosteres: Implication to Genome-lead drug discovery.2007
- Author(s)
  Fujii N
- Organizer
  2. World Congress of Pharmacy and Pharmaceutical Sciences
- Place of Presentation
  Beijing
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-18015027
[Presentation] Construction of 2-(aminomethyl)indole motif by Cu-catalyzed multi-component reaction.2007
- Author(s)
  Ohta Y., Oishi S., Fujii N., Ohno H.
- Organizer
  14th IUPAC Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
- Place of Presentation
  Nara
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and application of (Z)-alkene and (E)-fluoroalkene dipeptide isosteres as cis amide equivalents2007
- Author(s)
  Tomita K., Narumi T., Niida A., Oishi S., Ohno H., Fujii N.
- Organizer
  2nd annual meeding of Japan Chemical Biology Society
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 情報から制御へ:ゲノム情報収斂型創薬科学2007
- Author(s)
  藤井信孝
- Organizer
  21COE公開シンポジウム
- Place of Presentation
  京都
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-18060020
[Presentation] From amino acids to peptide isosteres : Implication to genome-lead drug discovery2007
- Author(s)
  Nobutaka Fujii, et al.
- Organizer
  2nd. World Congress of Pharmacy and Pharmaceutical Sciences
- Place of Presentation
  北京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Fluoroalkenes for peptidomimetics2007
- Author(s)
  Narumi T., Tomita K., Inokuchi E., Kobayashi K., Oishi S., Ohno H., Fujii N.
- Organizer
  44th Japanese Peptide Symposium
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 情報から制御へ:ゲノム情報収斂型創薬科学2007
- Author(s)
  藤井信孝
- Organizer
  21COE公開シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of Highly potent HIV fusion inhibitors2007
- Author(s)
  Tanaka M., Itoh S., Oishi S., Nishikawa H., Izumi K., Kodama E., MatsuokE M., Ohno H., Fujii N.
- Organizer
  2nd annual meeding of Japan Chemical Biology Society
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From Amino Acids to Peptide Isosteres: Implication to Genome-lead drug discovery.2007
- Author(s)
  Fujii N
- Organizer
  2. World Congress of Pharmacy and Pharmaceutical Sciences
- Place of Presentation
  Beijing
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-18060020
[Presentation] HIV activity of T-20 derivatives2007
- Author(s)
  Shimane K., Izumi K., Kodama E., Oishi S., Fujii N., Matsuoka M.
- Organizer
  21st Annual meeting of the Japan Society for AIDS research
- Place of Presentation
  Hiroshima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of chemokine receptor CXCE4 antagonists using bio-mimetic strategy.2007
- Author(s)
  Tamamura H., Tanaka T., Tsutsumi H., Ohashi N., Hiramatsu K., Araki T., Ojida A., Hamachi I., Wang Z., Peiper SC, Trent JO., Ueda S., Oishi S., Fujii N.
- Organizer
  20th American Peptide Symposium
- Place of Presentation
  Montreal
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Palladium-catalyzed synthesis of carbazole by tandem N-arylation and C-H activation.2007
- Author(s)
  Watanabe T., Ueda S., Oishi S., Fujii N., Ohno H.
- Organizer
  The 127th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] CXCR4 antagonists : Relevance to small cell lung cancer chemotherapy.2007
- Author(s)
  Nobutaka Fujii, et al.
- Organizer
  First JCA-AACR Special Joint Conference : The Latest Advances in Lung Cancer Research : From Basic Science to Therapeutics
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of highly potent HIV fusion inhibitors by application of EK concept2007
- Author(s)
  Itoh S., Oishi S., Nishikawa H., Tanaka M., Watanabe K., Izumi K., Kodama E., Matsuoka M., Ohno H., Fujii N.
- Organizer
  The 127th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Structure-affinity relationship study on fluorobenzoyl pentapeptides for GPR542007
- Author(s)
  Tomita K., Oishi S., Ohno H., Fujii N.
- Organizer
  The 127th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Propertie of intracellular fragment peptides of mouse prostaglandin E2 receptor mEP3b isoform.2007
- Author(s)
  Shinbo S., Yano Y., Oishi S., Fujii N., Sugimoto Y., Matsuzaki K.
- Organizer
  44th Japanese Peptide Symposium
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of GPR54 agonists as anti-metastasis agents.2007
- Author(s)
  Tomita K., Oishi S., Ohno H., Akamatsu M., Fujii N.
- Organizer
  The 8th workshop for cancer research for young scientists
- Place of Presentation
  Tateshina
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of novel CXCR4 antagonist having an indole scaffold2007
- Author(s)
  Katoh M., Ueda S., Inuki S., Oishi S., Ohno H., Fujii N.
- Organizer
  The 57th Kinki Regional Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Osaka
- Year and Date
  2007-10-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Unprecedented palladium- mediated carbon-fluorine bond cleavage : relevance to the synthesis of fluoroalkene dipeptidomimetics.2007
- Author(s)
  Narumi T., Inokuchi E., Tomita K, Oishi S., Ohno H., Fujii N.
- Organizer
  American Chemical Society 233rd National Meeting & Exposition
- Place of Presentation
  Chicago
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 情報から制御へ:ゲノム情報収斂型創薬科学2007
- Author(s)
  藤井信孝
- Organizer
  21COE公開シンポジウム
- Place of Presentation
  京都
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-18015027
[Presentation] Development of synthetic method for trifluoromethylalkene dipeptide isosteres by paradium-catalyzed carbonylation2007
- Author(s)
  Inokuchi E., Narumi T., Niida A., Oishi S., Ohno H., Fujii N.
- Organizer
  The 57th Kinki Regional Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Osaka
- Year and Date
  2007-10-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and applicatior of carbazoles by palladium-catalyzed tandem N-arylation and oxidative C-H activation.2007
- Author(s)
  Watanabe T., Ueda S., Oishi S., Fujii N., Ohno H.
- Organizer
  14th IUPAC Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
- Place of Presentation
  Nara
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Design and synthesis of novel HIV fusion inhibitors.2007
- Author(s)
  Oishi S., Ito S., Nishikawa H., Tanaka M., Ohno H., Otaka A., Izumi K., Kodama E., Matsuoka M., Fujii N.
- Organizer
  Virus Molecular Interactions : Therapeutic Targets
- Place of Presentation
  Oxford
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and application of Z-alkene and E-fluoroalkene dipeptide isosteres as cis-amide bond equivalents2007
- Author(s)
  Tomita K., Narumi T., Niida A., Oishi S., Ohno H., Fujii N.
- Organizer
  The 26th Symposium on Medicinal Chemistry
- Place of Presentation
  Sagamihara
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres : Lys-Lys and Glu-Glu type FADIs.2007
- Author(s)
  Narumi T., Kodera Y., Tomita K., Inokuchi E., Oishi S., Ohno H., Fujii N.
- Organizer
  234th ACS meeting & exposition
- Place of Presentation
  Boston
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] CXCR4 Antagonists; Relevance to Cancer Chemotherapy.2007
- Author(s)
  Nobutaka Fujii
- Organizer
  6th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Istanbul
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-18060020
[Presentation] Development of cyclic pentapeptide- based CXCR4 antagonists for the treatment of CXCR4-mediated diseases.2007
- Author(s)
  Ueda S., Oishi S., Wang Z., Ohno H., Peiper SC, Fujii N.
- Organizer
  First JCA-AACR Special Joint Conference : The Latest Advances in Lung Cancer Research : From Basic Science to Therapeutics
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development and application of novel photo-labile protecting groups (2) : One-pot coupling reactions of peptide fragments for chemical synthesis of membrane proteins2006
- Author(s)
  Ogawa T., Ueda S., Tomita K, Otaka A., Fujii N.
- Organizer
  The 126th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Drug Discovery for GPCR: From information to controls2006
- Author(s)
  Fujii N.
- Organizer
  The 269th Symposium of CBI society
- Place of Presentation
  Tokyo
- Year and Date
  2006-11-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Preparation of peptide thioester utilizing S-protected oxazolidinone derived from cysteine.2006
- Author(s)
  Otaka A., Ohta Y., Shigenaga A., Fujii N.
- Organizer
  The 1lth Korea-Japan Joint Symposium on Drug Design and Development
- Place of Presentation
  Cheju
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of fluoroalkenes by paradium-catalyzed C-F bond cleavage2006
- Author(s)
  Narumi T., Tomita K., Inokuchi E., Oishi S., Ohno H., Fujii N.
- Organizer
  The 32th Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Hiroshima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Structureactivity relationship study on GPR54 agonists.2006
- Author(s)
  Tomita K., Niida A., Oishi S., Ohno H., Akamatsu M., Fujii N.
- Organizer
  ICOB-5 & ISCNP-25 IUPAC International Conference on Biodiversity and Natural Products
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From information to controls2006
- Author(s)
  Fujii N.
- Organizer
  The 7th Nagai Nagayoshi Memorial Symposium
- Place of Presentation
  Tokushima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Structure-activity relationship studies on cyclic peptide-based CXCK4 antagonists.2006
- Author(s)
  eda S., Oishi S., Wang Z., Araki T., Tamamura H., Ohno H., NakashimaH., Peiper SC, Fujii N.
- Organizer
  ICOB-5 & ISCNP-25 IUPAC International Conference on Biodiversity and Natural Products
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of small-molecule CXCR4 antagonists2006
- Author(s)
  Tamamura H., Mizogami T., Hiramatsu K., Ogawa T., Ueda S., Tsutsumi H., Masuno H., Yamamoto N., Fujii N.
- Organizer
  The 126th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Kegio- and stereoselective synthesis of (Z)-alkene cis-Xaa-Pro dipeptide mimetics with organocopper- mediated anti-SN2'2006
- Author(s)
  Yoshikazu Sasaki, Takashi Tsuji, Ayumu Niida, Akira Shigenaga, Nobutaka Fujii, Akira Otaka
- Organizer
  29th European Peptide Symposium
- Place of Presentation
  Gdansk
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Discovery of novel low-molecular-weight GPR54 agonists.2006
- Author(s)
  Shinya Oishi, Kenji Tomita, Ayumu Niida, Miki Akamatsu, Toshihiko Masui, Ryuichiro Doi, Jean-Marc Navenot, Zixang Wang, Stephen C. Peiper, Nobutaka Fujii
- Organizer
  29th European Peptide Symposium
- Place of Presentation
  Gdansk
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Diastereoselective synthesis of (Z)-fluoroalkene dipeptide isosteres based on organocopper-mediated reduction/direct alkylation via transmetalation.2006
- Author(s)
  Tetsuo Narumi, Kenji Tomita, Ayumu Niida, Shinya Oishi, Hiroaki Ohno, Nobutaka Fujii
- Organizer
  29th European Peptide Symposium
- Place of Presentation
  Gdansk
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Structure-activity relationship studies on GPR54 agonists2006
- Author(s)
  Tomita K., Oishi S., Ohno H., Akamatsu M., Fujii N.
- Organizer
  The International Conference of 43rd Japanese Peptide Symposium and 4th Peptide Engineering Meeting
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From amino acids to peptide isosteres : Implication to genome-lead drug discovery.2006
- Author(s)
  Fujii N.
- Organizer
  2nd Intermational Symposium on Biomolecules and Related Compounds
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] GPCR創薬 : 情報から制御へ2006
- Author(s)
  藤井信孝
- Organizer
  第269回CBI研究会講演会
- Place of Presentation
  東京
- Year and Date
  2006-11-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of chemokine receptor CXCR4 antagonists having bivalent Zn-complex structure2006
- Author(s)
  Ogawa T., Tamamura H., Ojida A., Tsutsumi H., Masuno H., Nakajima H., Yamamoto N., Oishi S., Ohno H., Hamachi I., Fujii N.
- Organizer
  The 56th Kinki Regional Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Kyoto
- Year and Date
  2006-10-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesi of calbazoles by paradium-mediated tandem N-arylation and C-H activation2006
- Author(s)
  Watanabe T., Ueda S., Oishi S., Fujii N., Ohno H.
- Organizer
  The 56th Kinki Regional Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Kyoto
- Year and Date
  2006-10-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of carbazoles by paradium-catalyzed tandem N-arylation and C-H activation2006
- Author(s)
  Watanabe T., Ueda S., Oishi S., Fujii N., Ohno H.
- Organizer
  The 23rd Seminars on Organic Chemistry
- Place of Presentation
  Onuma
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From amino acids to peptide isosteres : Implications to peptide-lead drug templates for genome-lead drug discovery.2006
- Author(s)
  Nobutaka Fujii, Shinya Oishi, Tetsuo Narumi, Kenji Tomita, Hiroaki Ohno
- Organizer
  232nd American Chemical Society National Meeting & Exposition
- Place of Presentation
  San Francisco
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Novel synthesis of fluoroalkene isosteres utilizing paradium-catalyzed cleavage of C-F bond activation2006
- Author(s)
  Narumi T., Niida A., Tomita K., Oishi S., Otaka A., Ohno H., Fujii N.
- Organizer
  The 126th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of synthetic methodology toward (Z)-fluoro- alkene dipeptide isosteres based on the concept of organometalic-mediated C-F bond cleavage.2006
- Author(s)
  Tetsuo Narumi, Kenji Tomita, Ayumu Niida, Yasuyo Kodera, Shinya Oishi, Hiroaki Ohno, Nobutaka Fujii
- Organizer
  ICOB-5 & ISCNP-25 IUPAC International Conference on Biodiversity and Natural Products
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of (Z)-alkene-containing Pro dipeptide isosteres corresponding to cis-prolyl peptides2006
- Author(s)
  Sasaki Y., Niida A., Tsuji T., Shigenaga A., Fujii N., Otaka A.
- Organizer
  The 1lth Korea-Japan Joint Symposium on Drug Design and Development
- Place of Presentation
  Cheju
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] One-pot synthesis of carbazoles using paradium-catalyzed tandem N-arylation and C-H activation2006
- Author(s)
  Watanabe T., Ueda S., Oishi S., Fujii N., Ohno H.
- Organizer
  The 7th Nagai Nagayoshi Memorial Symposium
- Place of Presentation
  Tokushima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From amino acids to peptide isosteres and heterocycles : implications to vinylaziri- dines and amino allene chemistry.2006
- Author(s)
  Hiroaki Ohno, Tetsuaki Tanaka, Nobutaka Fujii
- Organizer
  11th Akabori conference
- Place of Presentation
  Regensburg
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Allylic hydrodefluorination under palladium catalysis for the synthesis of fluoroalkene dipeptide isosteres.2006
- Author(s)
  Narumi T., Tomita K., Inokuchi E., Oishi S., Ohno H., Fujii H.
- Organizer
  The 10th International KYOTO Conference on New Aspects of Organic Chemistry
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of 2-(aminomethyl)indoles by organocopper-catalyzed three-component coupling2006
- Author(s)
  Ohta Y., Oishi S., Fujii N., Ohno H.
- Organizer
  The 56th Kinki Regional Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Kyoto
- Year and Date
  2006-10-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From amino acids to peptide isosteres : Implications to peptide-lead drugtemplates for genome-lead drug discovery2006
- Author(s)
  Nobutaka Fujii, et al.
- Organizer
  232nd American Chemical Society National Meeting & Exposition
- Place of Presentation
  サンフランシスコ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Drag discovery targeting for 7TM-GPCRs2006
- Author(s)
  Fujii N.
- Organizer
  The 126th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Regio- and stereo-selective cis-Xaa-Pro-type (Z)-alkene dipeptide isosteres using organometal reagents2006
- Author(s)
  Sasaki Y., Tsuji T., Niida A., Fujii N., Otaka A.
- Organizer
  The 126th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of highly potent HIV fusion inhibitors based on EK-concept2006
- Author(s)
  Itoh S., Oishi S., Nishikawa H., Tanaka M., Izumi K., Kodama E., Matsuoki M., Ohno H., Fujii N.
- Organizer
  The 25th Symposium on Medicinal Chemistry
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesi and application of cis-amide equivalent alkene dipeptide isosteres2006
- Author(s)
  Oishi S., Niida A., Narumi T., Tomita K., Inokuchi E., Ohno H., Kitaura K., Fujii N., Otaka A., Inui K.
- Organizer
  The 32th Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Hiroshima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Structure-activity relationship study on novel CXCR4 antagonists having a cyclic scaffold2006
- Author(s)
  Watanabe T., Esaka R., Ogawa T., Ueda S., Tamamura H., Oishi S., Trent, JO., Wang, Z., Peiper, SC. Fujii N.
- Organizer
  The 126th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of novel antiviral agents against T-20 registant HIV2006
- Author(s)
  Itoh S., Oishi S., Nishikawa H., Tanaka M., Izumi K., Kodama E., Matsuoka M., Ohno H., Fujii N.
- Organizer
  The 56th Kinki Regional Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Kyoto
- Year and Date
  2006-10-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of novel CXCR4 antagonists having bivalent Zn-complexes2006
- Author(s)
  Ogawa T., Tamamura H., Ojida A., Tsutsumi H., Nakajima H., Oishi S., Ohno H., Hamachi I., Fujii N.
- Organizer
  The 25th Symposium on Medicinal Chemistry
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] A novel oxazolidine linker for the synthesis of peptide aldehydes.2006
- Author(s)
  Tanaka M., Oishi S., Ohno H., Fujii N.
- Organizer
  The International Conference of 43rd Japanese Peptide Symposium and 4th Peptide Engineering Meeting
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of chemical probes for the chemokine receptor CXCR4 involving radiolabeled T140 anglogs.2006
- Author(s)
  Tamamura H., Hanaoka H., Tsutsumi H., Ohashi N., Tanaka T., Mori T., Mukai T., Doi R., Saji H., Fujii N.
- Organizer
  The International Conference of 43rd Japanese Peptide Symposium and 4th Peptide Engineering Meeting
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] New peptide design for HIV-1 fusion inhibitors against T-20resistant HIV-1 variants.2006
- Author(s)
  Nishikawa H., Kodama E., Ito S., Kajiwara K., Izumi K., Oishi S., Matsuoka M., Fujii N.
- Organizer
  The 3rd Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists
- Place of Presentation
  Seoul
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Establishment anc clinical application of an enzyme immunoassay for metastin to determination of the human plasma levels.2006
- Author(s)
  Katagiri F., Tomita K., Oishi S., Takeyama M., Fujii N.
- Organizer
  The International Conference of 43rd Japanese Peptide Symposium and 4th Peptide Engineering Meeting
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of a novel photo-labile protecting group having 4(dimethylamino)phenacyl group and the application to peptide synthesis2006
- Author(s)
  Ueda S., Tomita K., Nomura M., Otaka A., Oishi S., Ohno H., Fujii N.
- Organizer
  1st Annual Meeting of Japan Chemical Biology Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] SAR and QSAR studies on N-terminal moieties of pentapeptide GPR54 agonists2006
- Author(s)
  Tomita K., Niida A., Harada T., Oishi S., Ohno H., Akamatsu M., Fujii N.
- Organizer
  The 126th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Structure-activity relationship studies on N-terminal acyl groups of pentapeptidic GPR54 agonists.2006
- Author(s)
  Tomita K., Oishi S., Ohno H., Akamatsu M., Fujii N.
- Organizer
  The 3rd Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists
- Place of Presentation
  Seoul
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Palladium-catalyzed synthesis of carbazole by tandem N-arylation and C-H activation.2006
- Author(s)
  Watanabe T., Ueda S., Oishi S., Fujii N., Ohno H.
- Organizer
  The 10th International KYOTO Conference on New Aspects of Organic Chemistry
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of fluoroalkenes by paradium-catalyzed C-F bond cleavage2006
- Author(s)
  Narumi T., Tomita K., Inokuchi E., Oishi S., Ohno H., Fujii N.
- Organizer
  26th Seminar on Organic Synthesis for Young Scientists
- Place of Presentation
  Osaka
- Year and Date
  2006-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of novel photolabile protecting groups for carboxyl- and amino-groups2006
- Author(s)
  Ogawa T., Ueda S., Oishi S., Ohno H., Fujii N.
- Organizer
  33rd Seminars on Organic Reactions
- Place of Presentation
  Kyotanabe
- Year and Date
  2006-08-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Stereoselective synthesis of (Z)-trifluoromethylalkene dipeptide isosteres and the application to bioactive peptides2006
- Author(s)
  Inokuchi E., Narumi T., Niida A., Tomita K., Oishi S., Ohno H., Fujii N.
- Organizer
  33rd Seminars on Organic Reactions
- Place of Presentation
  Kyotanabe
- Year and Date
  2006-08-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From genome to lead : medicinal chemistry beyond XXX-omics researches.2006
- Author(s)
  Fujii, N.
- Organizer
  The 1lth Korea-Japan Joint Symposium on Drug Design and Development
- Place of Presentation
  Cheju
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of novel photo-labile 4-(dimethylamino)phenacyl-type protecting groups for chemical biology2006
- Author(s)
  Ogawa T., Ueda S., Nomura M., Otaka A., Oishi S., Ohno H., Fujii N.
- Organizer
  Seminars on Biomedical Researches
- Place of Presentation
  Osaka
- Year and Date
  2006-09-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of 2-(aminomethyl)indoles by organocopper-mediated three-component coupling2006
- Author(s)
  Ohta Y., Oishi S., Fujii N., Ohno H.
- Organizer
  26th Seminar on Organic Synthesis for Young Scientists
- Place of Presentation
  Osaka
- Year and Date
  2006-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 7回膜貫通GPCRを分子標的とする創薬基盤の革新を目指して2006
- Author(s)
  藤井信孝
- Organizer
  日本薬学会第126年会
- Place of Presentation
  仙台
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From amino acids to peptide isosteres : Implication to genome-lead drug discovery2006
- Author(s)
  Nobutaka Fujii, et al.
- Organizer
  2nd Intermational Symposium on Biomolecules and Related Compounds
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development and application of novel photo-labile protecting groups (1) : 4(dimethylamino)phenacyl protecting groups for carboxy- and amino-groups group2006
- Author(s)
  Ueda S., Nomura M., Ogawa T., Otaka A., Fujii N.
- Organizer
  The 126th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Stereselective synthesi of (Z)-trifluororhethyl alkene dipeptide isosteres and the application to bioactive peptides2006
- Author(s)
  Inokuchi E., Narumi T., Niida A., Tomita K., Oishi S., Ohno H., Fujii N.
- Organizer
  The 41th Seminars on Natural Products
- Place of Presentation
  Hokkaido
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From genome to lead : medicinal chemistry beyond XXX-omics researches.2006
- Author(s)
  Kobutaka Fujii
- Organizer
  The 11th Korea-Japan Joint Symposium on Drug Design and Development
- Place of Presentation
  済州島
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] From genome to lead2006
- Author(s)
  Fujii N.
- Organizer
  The 8th Peptide Forum
- Place of Presentation
  Kyoto
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of fluoroalkenes by organometal-mediated C-F bond cleavage : Application to highly functionalized fluoroalkene dipeptide isosteres2006
- Author(s)
  Narumi T., Tomita K., Niida A., Oishi S., Otaka A., Ohno H., Fujii N.
- Organizer
  The 4th Symposium on Organic Chemistry - The Next Generation -
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Structure-activity relationship study on GPR54 agonists2006
- Author(s)
  Tomita K., Oishi S., Ohno H., Akamatsu M., Fujii N.
- Organizer
  The 34th Symposium on Structure-Activity Relationships
- Place of Presentation
  Niigata
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of anti-FIV agents having fusion inhibitory activiry2006
- Author(s)
  Kodera Y., Nishikawa H., Tanaka M., Mizukoshi F., Tsujimoto H., Kodama E., Matsuoka M., Oishi S., Ohno H., Fujii N.
- Organizer
  The 56th Kinki Regional Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Kyoto
- Year and Date
  2006-10-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Highly stereoselective synthesis of fluoroalkene isosteres and the application to bioactive peptides2006
- Author(s)
  Narumi T., Miyatani T., Niida A., Tomita K., Oishi S., Otaka H., Ohno H., Fujii N.
- Organizer
  The 126th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Palladium-catalyzed synthesis of carbazole by tandem N-arylation and C-H activation.2006
- Author(s)
  Watanabe T., Ueda S., Oishi S., Fujii N., Ohno H.
- Organizer
  26th Seminar on Organic Synthesis for Young Scientists
- Place of Presentation
  Osaka
- Year and Date
  2006-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] ゲノムからりードヘ2006
- Author(s)
  藤井信孝
- Organizer
  第8回ペプチドフォーラム. 「ペプチド・タンパク質合成の革新的方法論とChemical Biologyへの展開」
- Place of Presentation
  京都
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of 2-(aminomethyl)indoles by organocopper-mediated three-component coupling2006
- Author(s)
  Ohta Y., Oishi S., Fujii N.. Ohno H.
- Organizer
  The 32th Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Hiroshima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] 情報から制御へ2006
- Author(s)
  藤井信孝
- Organizer
  第7回長井長義記念シンポジウム
- Place of Presentation
  徳島
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Structure-activity relationship studies on cyclic peptide-based CXCR4 antagonists : Side-chain and backbone modifications.2006
- Author(s)
  Satoshi Ueda, Shinya Oishi, Zixuan Wang, Hiroaki Ohno, Stephen C. Peiper, Nobutaka Fujii
- Organizer
  232nd American Chemical Society National Meeting & Exposition
- Place of Presentation
  San Francisco
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Solid-phase synthesis of peptide aldehydes using an oxazolidine linker2006
- Author(s)
  Tanaka M., Oishi S., Ohno H., Fujii N.
- Organizer
  The 7th Nagai Nagayoshi Memorial Symposium
- Place of Presentation
  Tokushima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Stereoselective of multi-functionalized fluoroalkene dipeptide isosteres2005
- Author(s)
  Narumi T., Niida A., Tomita K., Oishi S., Ohno H., Otaka H., Fujii N.
- Organizer
  Seminar on Organic Synthesis for Young Scientists
- Place of Presentation
  Kobe
- Year and Date
  2005-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of peptide thioester based on N-S acyltransfer utilizing cysteine-derived acyloxazolidinone with practical application to peptide synthesis.2005
- Author(s)
  Ohta Y., Itoh S., Fujii N., Otaka A.
- Organizer
  42th Japanese Peptide Symposium
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of a novel photo-labile protecting group directed to chemical synthesis of 7TM-GPCR2005
- Author(s)
  Ueda S., Tomita K., Nomura M., Otaka A., Fujii N.
- Organizer
  The 31th Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of tokaramide A and miraziridine A isolated from sponges2005
- Author(s)
  Konno H., Kubo K., Makabe H., Fujii N., Nosaka K., Akaji K.
- Organizer
  42th Japanese Peptide Symposium
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Stereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres2005
- Author(s)
  Narumi T., Niida A., Tomita K., Oishi S., Otaka A., Ohno H., Fujii N.
- Organizer
  42th Japanese Peptide Symposium
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of alkene-type peptide isosteres and the application to peptide transporter PEPT12005
- Author(s)
  Niida A., Tomita K., Tanigaki H., Terada T., Mizumoto M., Ohno H., Tamamura H., Otaka A., Inui K., Fujii N.
- Organizer
  42th Japanese Peptide Symposium
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Stereoselective synthesis of [L-Arg, L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isostere and the application to analigues of CXCR4 antagonist FC1312005
- Author(s)
  Tamamura H., Hiramatsu K., Ueda S., Fujii N., Zixuan W., Peiper SC, Trent, JO., Yamamoto N., Nakajima H., Otaka A.
- Organizer
  The 31th Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis and bioevaluation of peptidomimetics of CXCR4 antagonist FC1312005
- Author(s)
  Tamamura H., Hiramatsu K., Araki T., Ueda S., Oishi S., Esaka R., Zixuan Wang, Stephen C. Peoper, John 0. Trent, Nakajima H., Yamamoto N., Otaka A., Fujii N.
- Organizer
  42th Japanese Peptide Symposium
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Structure-activity study on small-molecule GPR54 agonists2005
- Author(s)
  Tomita K., Niida A., Oishi S., Ohno H., Otaka A., Fujii N.
- Organizer
  The 24th Symposium on Medicinal Chemistry
- Place of Presentation
  Oosaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of thioesters using Cys-derivec acyloxazolidinone and the application to peptide synthesis2005
- Author(s)
  Ohta Y., Itoh S., Fujii N., Otaka A.
- Organizer
  Seminar on Organic Synthesis for Young Scientists
- Place of Presentation
  Kobe
- Year and Date
  2005-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of cis-amide equivlalent alkene dipeptide isosteres and the application to peptide transporter PEPT12005
- Author(s)
  Niida A., Tomita K., Tanigaki H., Terada T., Mizumoto M., Ohno H., Tamamura H., Otaka A., Inui K., Fujii N.
- Organizer
  The 24th Symposium on Medicinal Chemistry
- Place of Presentation
  Oosaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Structure-activity relationship study on RW-amide-type hOT7T175 agonist2005
- Author(s)
  Tomita K., Niida A., Oishi S., Ohno H., Otaka A., Fujii N.
- Organizer
  42th Japanese Peptide Symposium
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Elucidation of substrate recognition of peptide transporter PEPT1 using alkene-type peptide isosteres2005
- Author(s)
  Niida A., Tomita K., Tanigaki H., Fujii N., Tamamura H., Otaka A., Terada T., InuiK.
- Organizer
  The 31th Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development and application of indium-mediated regio- and stereo-selective radical cyclization2005
- Author(s)
  Yanada R., Kohiga S., Nishimori N., Mitsuya H., Fujii N., Takemoto Y.
- Organizer
  The 31th Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Stereoselective of multi-functionalized fluoroalkene dipeptide isosteres2005
- Author(s)
  Narumi T., Niida A., Tomita K, Oishi S., Ohno H., Otaka A., Fujii N.
- Organizer
  The 24th Symposium on Medicinal Chemistry
- Place of Presentation
  Oosaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Development of new photoremovable protecting group and its application toward chemical synthesis of 7TM-GPCR2005
- Author(s)
  Ueda S., Otaka A., Tamamura H., Fujii N.
- Organizer
  20th American Peptide Symposium
- Place of Presentation
  San Diego
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of cis-alkene-type Ala-Pro peptidomimetics using organocopper-reagent2005
- Author(s)
  Sasaki Y., Niida A., Tsuji T., Fujii N., Otaka A.
- Organizer
  42th Japanese Peptide Symposium
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Synthesis of cysteine proteases okaramide A and miraziridine A2005
- Author(s)
  Konno H., Nosaka K., Akaji K., Kubo K, Makabe H., Fujii N.
- Organizer
  The 31th Symposium on Progress in Organic Reactions in the Life Sciences
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Unequivocal synthesis of (Z)-alkene or (E)-fluoroalkene dipeptide isosteres via DKP mimetics to probe structural orrequirements of peptide transporter.2005
- Author(s)
  Niida A., Oishi S., Mizumoto M., Sasaki Y., Tomita K., Tamamura H., Otaka A., Terada T., Inui K. Fujii N.
- Organizer
  19th American Peptide Symposium
- Place of Presentation
  San Diego
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209004
[Presentation] Direct Construction of Fused Indoles by Gold-Catalyzed Cascade Cyclization of Conjugated Diynes
- Author(s)
  Saori Naoe, Shinya Oishi, Nobutaka Fujii, Hiroaki Ohno
- Organizer
  第８回集積有機合成国際シンポジウム（ISIS-8）
- Place of Presentation
  東大寺総合文化センター (奈良県奈良市）
- Year and Date
  2013-09-23 – 2013-09-26
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 光アフィニティープローブを利用したキスペプチン類の受容体結合残基の同定
- Author(s)
  三須良介、大石真也、説田章平、野口太朗、金田雅仁、大野浩章、藤井信孝
- Organizer
  第8回ケミカルバイオロジー学会年会
- Place of Presentation
  東京医科歯科大学　（東京都文京区）
- Year and Date
  2013-06-19 – 2013-06-21
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] NK3受容体アゴニストの生体内安定性評価と新規誘導体の創製
- Author(s)
  三須良介、大石真也、山田愛、山本昂輝、野口太朗、大野浩章、山村崇、岡村裕昭、松田二子、大蔵聡、藤井信孝
- Organizer
  第11回GPCR研究会
- Place of Presentation
  日本科学未来館　みらいCANホール　（東京都江東区）
- Year and Date
  2014-05-09 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 化合物アレイを用いた新規mdm2/mdmx-p53阻害剤の探索法の開発とその応用
- Author(s)
  ○野口太朗、大石真也、久保達彦、大野浩章、近藤恭光、斎藤臣雄、長田裕之、藤井信孝
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  アステールプラザ（広島県広島市）
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] Structure-activity Relationship Study of Tachykinin Peptides for Development of Novel Neurokinin-3 Receptor Selective Agonists
- Author(s)
  Ryosuke Misu, Shinya Oishi, Taro Noguchi, Ai Yamada, Hiroaki Ohno, Fuko Matsuda, Satoshi Ohkura, Nobutaka Fujii
- Organizer
  23rd American Peptide Symposium
- Place of Presentation
  ヒルトンワイコロアホテル　（米国ハワイ州ワイコロワ）
- Year and Date
  2013-06-22 – 2013-06-27
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] キネシンモータータンパク質KSP阻害剤の創製研究-連続縮環型分子の変換による溶解性改善-
- Author(s)
  竹内智起、大石真也、金田雅仁、大野浩章、澤田潤一、浅井章良、藤井信孝
- Organizer
  第11回次世代を担う有機化学シンポジウム
- Place of Presentation
  日本薬学会長井記念ホール (東京都渋谷区）
- Year and Date
  2013-05-24 – 2013-05-25
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 金触媒を用いた共役ジインとピロールの分子間 [4 + 2] 型反応によるインドール骨格の構築
- Author(s)
  松田優佳、直江紗織、大石真也、藤井信孝、大野浩章
- Organizer
  第40回反応と合成の進歩シンポジウム
- Place of Presentation
  東北大学川内萩ホール　（宮城県仙台市）
- Year and Date
  2014-11-10 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 金触媒によるアジドイナミドの連続環化反応を用いたインドロキノリン骨格の一挙構築
- Author(s)
  時水勇輔、大石真也、藤井信孝、大野浩章
- Organizer
  第40回反応と合成の進歩シンポジウム
- Place of Presentation
  東北大学川内萩ホール　（宮城県仙台市）
- Year and Date
  2014-11-10 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] スフィンゴシンキナーゼ阻害活性を有するJaspine B誘導体の構造活性相関研究
- Author(s)
  本田真歩、宮垣潤、吉光佑二、岩田顕、大槻和裕、丸山透、大石真也、大野浩章、藤井信孝
- Organizer
  日本ケミカルバイオロジー学会　第9回年会
- Place of Presentation
  大阪大学（大阪府豊中市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] 金触媒を用いた三成分環化反応によるジヒドロピラゾールの合成とCK2阻害剤開発への応用
- Author(s)
  大野浩章、鈴木大和、侯増燁、呉竜英、仲西功、平澤明、大石真也、藤井信孝
- Organizer
  第43回複素環化学討論会
- Place of Presentation
  長良川国際会議場　（岐阜県岐阜市）
- Year and Date
  2013-10-17 – 2013-10-19
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] パラジウム触媒による連続環化反応を用いた四環性スピロインドール類の合成
- Author(s)
  岩田　顕、井貫晋輔、大石真也、藤井信孝、大野浩章
- Organizer
  第39回反応と合成の進歩シンポジウム
- Place of Presentation
  九州大学医学部百年講堂　（福岡県福岡市）
- Year and Date
  2013-11-05 – 2013-11-07
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 鉄(II)イオン配位性ペプチドの設計と機能評価
- Author(s)
  小林由佳、大石真也、大野浩章、藤井信孝
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸　（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 化合物アレイを用いた新規mdm2/mdmx-p53阻害剤の探索法の開発とその応用
- Author(s)
  ○野口太朗、大石真也、久保達彦、大野浩章、近藤恭光、斎藤臣雄、長田裕之、藤井信孝
- Organizer
  第63回日本薬学会近畿支部大会
- Place of Presentation
  同志社女子大学（京都府京田辺市）
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] Peptide-based Drug Discovery
- Author(s)
  Nobutaka Fujii
- Organizer
  4th Asia-Pacific International Peptide Symposium
- Place of Presentation
  ホテル阪急エキスポパーク　（大阪府吹田市）
- Year and Date
  2013-11-06 – 2013-11-08
- Invited
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] パラジウム触媒を用いた中員環形成反応によるLaurencia族環状エーテルの構築：Laurendecumallene Bの合成研究
- Author(s)
  大野浩章、吉光佑二、井貫晋輔、大石真也、藤井信孝
- Organizer
  第39回反応と合成の進歩シンポジウム
- Place of Presentation
  九州大学医学部百年講堂　（福岡県福岡市）
- Year and Date
  2013-11-05 – 2013-11-07
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Structure-activity Relationship Study of Tachykinin Peptides for Evaluation of Biological Stability of Neurokinin-3 Receptor Agonists for the Development of Novel Biostable Analogs
- Author(s)
  Ryosuke Misu, Shinya Oishi, Taro Noguchi, Ai Yamada, Hiroaki Ohno, Fuko Matsuda, Satoshi Ohkura, Nobutaka Fujii
- Organizer
  4th Asia-Pacific International Peptide Symposium
- Place of Presentation
  ホテル阪急エキスポパーク　（大阪府吹田市）
- Year and Date
  2013-11-06 – 2013-11-08
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Identification of Novel CXCR7 Selective Ligands with Cyclic Pentapeptide Scaffold
- Author(s)
  Tomoko Kuroyanagi, Shinya Oishi, Tatsuhiko Kubo, Yuka Kobayashi, Ryosuke Misu, Hiroaki Ohno, Nicolas Montpas, Nikolaus Heveker, Yasushi Yoshikawa, Toshio Furuya, Nobutaka Fujii
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学　（徳島県徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 環状ペンタペプチド骨格を有する新規CXCR7選択的リガンドの創製
- Author(s)
  黒柳友子、大石真也、久保達彦、小林由佳、三須良介、大野浩章、Montpas Nicolas、Heveker Nikolaus、吉川寧、古谷利夫、藤井信孝
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸国際会議場　（兵庫県神戸市）
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 新規CXCR7選択的リガンドの創製：CXCR4拮抗剤からの受容体選択性の変換
- Author(s)
  黒柳友子、大石真也、久保達彦、小林由佳、三須良介、大野浩章、Montpas Nicolas、Heveker Nikolaus、吉川寧、古谷利夫、藤井信孝
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学　（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] クロスメタセシス反応を利用したスフインゴシンキナーゼ阻害剤の創製研究
- Author(s)
  本田真歩、宮垣潤、吉光佑二、大槻和裕、丸山透、中村真也、仲西功、大石真也、大野浩章、藤井信孝
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学　（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] スフィンゴシンキナーゼ阻害活性を有するJaspine B誘導体の構造活性相関研究
- Author(s)
  本田真歩、宮垣潤、吉光佑二、岩田顕、大槻和裕、丸山透、中村真也、仲西功、大石真也、大野浩章、藤井信孝
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] 金触媒を用いた共役ジインの三連続反応による縮環カルバゾールの合成
- Author(s)
  田口将光、時水勇輔、大石真也、藤井信孝、大野浩章
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学　（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] OPTIMIZATION OF NEUROKININ-3 RECEPTOR (NK3R) SELECTIVE AGONISTS
- Author(s)
  Koki Yamamoto, Shinya Oishi, Ryosuke Misu, Taro Noguchi, Hiroaki Ohno, Takashi Yamamura, Hiroaki Okamura, Nobutaka Fujii
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学　（徳島県徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 新規フェニルピラゾール誘導体の抗HIV活性に関する構造活性相関研究
- Author(s)
  岡崎志穂、水原司、加藤貴之、平井敦、栗原秀樹、嶋田泰宏、谷口雅彦、前田英樹、戸上博昭、志村和也、松岡雅雄、竹内智起、大野浩章、大石真也、藤井信孝
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  アステールプラザ　（広島県広島市）
- Year and Date
  2013-11-20 – 2013-11-22
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 新規ニューロキニン-3受容体アゴニストの創製研究
- Author(s)
  山本昂輝、大石真也、三須良介、野口太朗、大野浩章、山村崇、岡村裕昭、藤井信孝
- Organizer
  日本ケミカルバイオロジー学会　第9回年会
- Place of Presentation
  大阪大学　（大阪府吹田市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Kinesin spindle protein (KSP) inhibitors with carbazole and diaryl amine scaffolds
- Author(s)
  Tomoki Takeuchi, Shinya Oishi, Masato Kaneda, Hiroaki Ohno, Jun-ichi Sawada, Akira Asai, Nobutaka Fujii
- Organizer
  246th American Chemical Society National Meeting and Exposition
- Place of Presentation
  Indiana convention center　（米国インディアナ州インディアナポリス）
- Year and Date
  2013-09-08 – 2013-09-12
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Jaspine Bおよびその誘導体の多様性指向型合成研究
- Author(s)
  宮垣潤、吉光佑二、大石真也、藤井信孝、大野浩章
- Organizer
  第62回日本薬学会近畿支部大会
- Place of Presentation
  武庫川女子大学（兵庫県）
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] ピリミドベンゾチアジン誘導体の新規合成法の開発と抗HIV剤を指向した構造活性相関研究
- Author(s)
  水原司、大石真也、大野浩章、志村和也、松岡雅雄、藤井信孝
- Organizer
  第62回日本薬学会近畿支部大会
- Place of Presentation
  武庫川女子大学（兵庫県）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Identification of Novel MDM2/MDMX-p53 interaction inhibitors by chemical array technology
- Author(s)
  ○野口太朗、大石真也、久保達彦、大野浩章、近藤恭光、斎藤臣雄、長田裕之、藤井信孝
- Organizer
  2nd Annual Conference ICBS2013
- Place of Presentation
  京都大学芝蘭会館（京都府京都市）
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] スフィンゴシンキナーゼ阻害活性を有するJaspine B誘導体の構造活性相関研究
- Author(s)
  本田真歩、宮垣潤、吉光佑二、岩田顕、大槻和裕、丸山透、大石真也、大野浩章、藤井信孝
- Organizer
  日本ケミカルバイオロジー学会　第9回年会
- Place of Presentation
  大阪大学　（大阪府吹田市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Development of Carbazole- and Diaryl Amine-type Kinesin Spindle Protein (KSP) Inhibitors
- Author(s)
  Tomoki Takeuchi, Shinya Oishi, Masato Kaneda, Hiroaki Ohno, Tatsuhide Kure, Shinya Nakamura, Isao Nakanishi, Jun-ichi Sawada, Akira Asai, Nobutaka Fujii
- Organizer
  2nd Annual Conference ICBS2013
- Place of Presentation
  京都大学芝蘭会館　（京都府京都市）
- Year and Date
  2013-10-07 – 2013-10-09
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Synthesis of the fused tetracyclic spiroindoles via palladium-catalyzed cascade reaction
- Author(s)
  Akira Iwata, Shinsuke Inuki Shinya Oishi, Hiroaki Ohno, Nobutaka Fujii
- Organizer
  246th American Chemical Society National Meeting and Exposition
- Place of Presentation
  Indiana convention center　（米国インディアナ州インディアナポリス）
- Year and Date
  2013-09-08 – 2013-09-12
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] ケミカルバイオロジーを基盤とする創薬研究
- Author(s)
  藤井信孝
- Organizer
  生命分子機能研究会セミナー2013
- Place of Presentation
  長浜バイオ大学（滋賀県）
- Invited
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] Development of novel neurokinin-3 receptor selective agonists with resistance against proteolytic degradation
- Author(s)
  Ryosuke Misu, Shinya Oishi, Ai Yamada, Koki Yamamoto, Taro Noguchi, Hiroaki Ohno, Takashi Yamamura, Hiroaki Okamura, Fuko Matsuda, Satoshi Ohkura, Nobutaka Fujii
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学　（徳島県徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 新規抗HIV剤を指向したベンゾイソチアゾロピリミジン誘導体の構造活性相関研究
- Author(s)
  岡崎志穂、水原司、志村和也、村山大人、松岡雅雄、大野浩章、大石真也、藤井信孝
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸国際会議場　（兵庫県神戸市）
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] ペプチダーゼ耐性を有する新規NK3受容体アゴニストの創製研究
- Author(s)
  三須良介、大石真也、山田愛、山本昂輝、野口太朗、大野浩章、山村崇、岡村裕昭、松田二子、大蔵聡、藤井信孝
- Organizer
  日本ケミカルバイオロジー学会　第9回年会
- Place of Presentation
  大阪大学　（大阪府吹田市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Jaspine Bおよびその誘導体の多様性指向型合成研究
- Author(s)
  宮垣潤、吉光佑二、大石真也、藤井信孝、大野浩章
- Organizer
  第62回日本薬学会近畿支部大会
- Place of Presentation
  武庫川女子大学（兵庫県）
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 連続縮環型分子の修飾によるKSP阻害剤の溶解性改善
- Author(s)
  竹内智起、大石真也、金田雅仁、大野浩章、中村真也、仲西功、山根正敏、澤田潤一、浅井章良、藤井信孝
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  アステールプラザ　（広島県広島市）
- Year and Date
  2013-11-20 – 2013-11-22
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 天然物の鏡像体化合物群の活用を目指した新規スクリーニング法の開発
- Author(s)
  野口太朗、大石真也、本田香織、近藤恭光、斎藤臣雄、大野浩章、長田裕之、藤井信孝
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] Development of Photoaffinity Probes for Characterization of the Receptor Binding Residues in Kisspeptins
- Author(s)
  Shinya Oishi, Shohei Setsuda, Ryosuke Misua Taro Noguchi, Masato Kaneda, Hiroaki Ohno, Barry Evans, Jean-Marc Navenot, Stephen C. Peiper, Nobutaka Fujii
- Organizer
  23rd American Peptide Symposium
- Place of Presentation
  ヒルトンワイコロアホテル　（米国ハワイ州ワイコロワ）
- Year and Date
  2013-06-22 – 2013-06-27
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] クロスメタセシス反応を利用したスフインゴシンキナーゼ阻害剤の創製研究
- Author(s)
  本田真歩、宮垣潤、吉光佑二、大槻和裕、丸山透、中村真也、仲西功、大石真也、大野浩章、藤井信孝
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24659046
[Presentation] ケミカルバイオロジーを基盤とする創薬研究
- Author(s)
  藤井信孝
- Organizer
  生命分子機能研究会セミナー2013
- Place of Presentation
  長浜バイオ大学（滋賀県）
- Invited
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] 金触媒を用いたベンゾフランによる分子内ヒドロアリール化反応の検討
- Author(s)
  坂井由葵、大石真也、藤井信孝、大野浩章
- Organizer
  第39回反応と合成の進歩シンポジウム
- Place of Presentation
  九州大学医学部百年講堂　（福岡県福岡市）
- Year and Date
  2013-11-05 – 2013-11-07
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Synthesis of IB-01212 by Site-Selective N-Methylation of Peptide Bonds
- Author(s)
  Ryota Nabika, Shinya Oishi, Ryosuke Misu, Hiroaki Ohno and Nobutaka Fujii
- Organizer
  4th Asia-Pacific International Peptide Symposium
- Place of Presentation
  ホテル阪急エキスポパーク　（大阪府吹田市）
- Year and Date
  2013-11-06 – 2013-11-08
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] Synthetic Studies on Coibamide A
- Author(s)
  Ryota Nabika, Shinya Oishi, Hiroaki Ohno, Nobutaka Fujii
- Organizer
  The First Asian Conference for ''MONODUKURI'' Strategy by Synthetic Organic Chemistry
- Place of Presentation
  Southern Beach Hotel & Resort Okinawa（沖縄県糸満市）
- Year and Date
  2013-07-17 – 2013-07-19
- Data Source
  KAKENHI-PROJECT-23390025
[Presentation] C-H官能基化反応、及び芳香族求核置換反応によるピリミド［1,2-c］ベンゾチアジン-6-イミンとその誘導体の効率的合成法の開発
- Author(s)
  Mizuhara T, Oishi S, Fujii N, Ohno H.
- Organizer
  第31回有機合成若手セミナー「明日の有機合成を担う人のために」
- Place of Presentation
  京都大学（京都府）
- Data Source
  KAKENHI-PROJECT-23390025

1. OISHI Shinya (80381739)

# of Collaborated Projects: 11 results

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Fujii Nobutaka 藤井 信孝

FUJII Nobutaka 藤井 信孝

Research Projects

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Co-Researchers

Development of Novel Drug Discovery Technologies for Target Proteins with Elusive Molecular BasisPrincipal Investigator

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Development of anti HIV peptide applying multifunctional polypeptide

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Potential new chemotherapy for breast cancer therapy with a novel KSP inhibitor

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Develoment of a screening platform using mirror-image proteins and their application to drug discovery

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Elucidation of the molecular mechanism of insulin resistance by investigating TBP-2/Txnip and chemical biology

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Development and application of a novel screening technolgy toward effective uses of chemical libraryPrincipal Investigator

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Practical medicinal chemistry on the basis of protein chemistry, computational science and synthetic technologies for a variety of heterocyclesPrincipal Investigator

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多重標的創薬概念に基づくがん化学療法の新機軸Principal Investigator

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GPCR周辺の細胞外環境解明のためのケミカルプローブの創出と応用Principal Investigator

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癌転移・骨髄依存薬物耐性の動的超分子機構解明のケミカルプローブ創出と創薬展開Principal Investigator

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有機化学を基盤にしたGPCR細胞外環境のケミカルバイオロジー研究Principal Investigator

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ドラッグ指向性化合物バンクの構築と創薬展開Principal Investigator

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CXCR4を分子標的とした癌転移およびストローマ細胞依存性薬物耐性の克服Principal Investigator

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Fujii Nobutaka 藤井信孝

FUJII Nobutaka 藤井信孝