• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

HARA Yoshitaka  原 宜興

ORCIDConnect your ORCID iD *help
… Alternative Names

原 宣興  ハラ ヨシタカ

HARA YOSHITAKA  原 宣興

Less
Researcher Number 60159100
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2014 – 2019: 長崎大学, 医歯薬学総合研究科(歯学系), 教授
2015: 長崎大学, 医歯学総合研究科(歯学系), 教授
2015: 長崎大学, 大学院医歯薬学総合研究科(歯学系), 教授
2011 – 2015: 長崎大学, 医歯(薬)学総合研究科, 教授
2014: 長崎大学, 大学院医歯薬学総合研究科, 教授 … More
2007 – 2012: Nagasaki University, Graduate School of Biomedical Sciences, Professor
2007: Nagasaki University, 医歯(薬)学総合研究科, 教授
2006: 長崎大学, 大学院医歯薬学総合研究科, 教授
2002 – 2005: Graduate School of Biomedical Sciences, Professor, 大学院・医歯薬学総合研究科, 教授
2000 – 2001: 長崎大学, 歯学部, 教授
1989 – 1999: 長崎大学, 歯学部, 助教授
1996: 長崎大学, 医学部, 助教授
1991: 長崎大学, 歯学部・歯科保存学第2講座, 助教授
1987 – 1988: Kyushu University, Faculty of Dentistry Hospital, Lecture, 歯学部付属病院, 講師
1986 – 1988: 九州大学, 歯学部附属病院, 講師 Less
Review Section/Research Field
Principal Investigator
Conservative dentistry / Periodontal dentistry / Periodontal dentistry / Periodontology
Except Principal Investigator
Periodontal dentistry / Conservative dentistry / Periodontology / Morphological basic dentistry / 病態科学系歯学(含放射線系歯学) / Periodontal dentistry
Keywords
Principal Investigator
骨吸収 / 病理組織学的研究 / LPS / TNF-α / Bone resorption / Immunohistological study / 免疫組織学的研究 / 歯周炎 / RANKL / OPG … More / Osteoclast / 破骨細胞 / Histopathological study / IL-4 / IFN-γ / Tリンパ球 / ラット / インプラント周囲炎 / T cell / ラットインプラント周囲炎発症モデル / glycyrrhetinic acid / グリチルリチン酸 / アタッチメントロス / Minor tooth movement / Hydroxyapatite / 矯正的歯牙移動 / 歯槽骨 / 歯周組織 / 歯牙小矯正移動 / ハイドロキシアパタイト / B cell / 好中球 / B細胞 / IL-1 β / Interferron-γ / IL-1β / Interferon-γ / IL-1B / LSP / COX2 / Odontoclast / Periodontal ligament tissue / Root resorption / 歯周組織再生 / 歯根膜細胞 / COX-2 / 破歯細胞 / 歯根膜組織 / 歯根吸収 / periodontal disease / IFN-gamma / IL-1 / サイトカイン / 歯肉溝浸出液 / 免疫組織学的検索 / SCID mouse / Nude mouse / 病理組織学的検索 / T細胞 / SCIDマウス / ヌードマウス / fibronectin / laminin / collagen type IV / basement membrane / 間接螢光抗体法 / 細胞外基質 / ポケット上皮 / Type IV コラ-ゲン / フィブロネクチン / ラミニン / タイプIVコラ-ゲン / 基底膜 / S. aureus / A. actinomycetemcomitans / 歯周ポケット / 実験病理学的研究 / インプラント / 免疫複合体 / interleukin-4 / interferon-γ / LPS誘導型骨吸収 / リポ多糖(LPS) / リポ多糖 / 感作 / 免疫系細胞 … More
Except Principal Investigator
歯周病原細菌 / 骨吸収 / 歯周病 / 辺縁性歯周炎 / 内毒素 / 歯周炎 / 破骨細胞 / サイトカイン / 結晶化ガラス / Bacteroides gingivalis / Periodontopathic bacteria / 歯周病原性細菌 / インフラマソーム / IL-4 / 歯学 / RANKL / 自然免疫 / IL-1 / fibroblasts / 線維芽細胞 / Notch / CCN3 / Runx2 / Actinobacillus actinomycetemcomitans / 歯周組織 / in situ hybridization / mRNA / TNF-alpha / P.gingivalis / Gingiva / Periodontitis / 歯肉 / Histopathological study / Endotoxin / 病理組織学的研究 / 咬合性外傷 / NLRC4 / NLRP1 / IL-1β / カスパーゼ1 / NLRP3 / IFN-γ / 免疫組織化学 / TNF-α / 細胞・組織 / 再生医学 / 移植・再生医療 / Porphyromonas gingivalis / ペプチドグリカン / TLR4 / TLR2 / 歯肉縁下プラーク / 歯肉縁上プラーク / ハイドロキシアパタイト / HMGB-1 / アポトーシス / マウス / 外傷性咬合 / HMGB1 / 骨細胞 / 結晶 / 歯石 / 免疫感作 / 老化 / Wnt / C1q / 動物モデル / 老化促進因子 / 歯周ポケット形成 / Soperoxide / Polymorphonuclear Leukocyte / Periodontal Disease / 受容体(Receptor) / 活性酸素 / 多形核白血球 / 白血球生物活性 / 抗体価 / 抑制物質 / Macrophage / T Cell B Cell / IgG antibody / Chronic Inflammatory Periodontal Disease / Outer membrane / Cell wall成分 / 血中抗体量 / ランゲルハンス細胞 / マクロファージ / Tcell Bcell / IgG抗体 / 血中抗体価 / alveolar bone / tissue eneineerin / periodontal tissue / cell transplantation / 歯槽骨 / ティッシュエンジニアリング / 細胞移植 / Protease / Escape from immune surveillance / Innate immunity / 蛋白分解酵素 / 免疫逃避 / integrin / tenascin-C / fibronectin / extracellular matrix / periodontal regenerative therapy / α5β1インテグリン / テネイシン-C / フィブロネクチン / インテグリン / テネイシン / フィヌロネクチン / 細胞外マトリクス / 歯周再生療法 / bone regeneration / evolution / frog / Mesenchymal stem cell / osteoblast / 両生類 / 細胞分化 / 再生療法 / 再生 / 軟骨内骨化 / アフリカツメガエル / BMP / 骨形成 / 骨再生 / 進化 / カエル / 間葉系幹細胞 / 骨芽細胞 / Time of infection / Peri-impantitis / Implant / 黒色色素産生嫌気性桿菌 / 歯周病関連菌 / 感染時期 / インプラント周囲炎 / インプラント / Periodontal pocket / Periodontal tissue / Lipopolysaccharide / 接合上皮 / 歯周ポケット / リポ多糖 / bone resorptin / IFN-gamma / In situ hybridization / gingival crevicular fluid / protease inhibitor / experimental gingivitis / lysosomal enzyme / periodontal disease / medullasin / cathepsin G / 炎症歯肉 / 好中球 / カテプシンD / カテプシンE / 実験的歯肉炎 / 歯肉溝滲出液 / プロテアーゼインヒビター / 実験歯肉炎 / リソゾーム性酵素 / 歯周疾患 / メダラシン / カテプシンG / Cytokine / RT-PCR method / 受容体系遺伝子 / 細胞接着分子 / 逆転写酵素PCR法 / Alveolar bone resorption / Periodontal disease associated bacteria / 免疫系細胞 / B.gingivalis / 歯槽骨吸収 / macrophage / Monocyte / Natural killer cell / B cell / T cell / Monoclonal antibody / Immunohistochemistry / 単球・マクロファ-ジ / B細胞 / T細胞 / インタ-ロイキン / リンパ球 / 単球・大食細胞 / NK細胞 / βリンパ球 / Tリンパ球 / モノクロ-ナル抗体 / 辺緑性歯周炎 / Osteoclast / Bone resorption / Node mouse / 血清抗体 / EIA法 / ELISA法 / ヌ-ドマウス / 人工歯冠鋳造用結晶化ガラス合成開発ー周辺機器の開発 / 人工歯石創成 / 石灰化現象 / 基底板様構造物 / 電顕観察 / 培養細胞 / 歯科用インプラント / 歯科用埋没材 / 鋳造歯冠修復 / 模型歯 / AIM2 / カスパーゼ5 / Caspase 5 / Caspase 4 / Caspase 1 / ピロトーシス / カスパーゼ4 / グリブリド / osteoclast / 吸収活性 / RANKL前刺激 / TNFa / TNFα / LPS / グラム陰性菌 / 性別 / 年齢 / 歯肉炎指数 / Toll-like receptor / 遺伝子多型 / 炎症性サイトカイン / Toll-like receptor 2 / Toll-like receptor 4 / ケニア / HIV感染 / HIV / HIV / エイズ / HIVに対する抗体価 / 歯周病原細菌感染 / IL-18 / 歯周病源細菌 / カスパーゼ-1 / NALP3 / TLR / Th2 / Th 17 / IL-23 / IL-10 / Th1 / IL-17 / Th17 / 接着斑 / 増殖因子 / 幹細胞 / シクナル伝達 / ApoE / IFNγ / インターフェロンγ / CD40 ligand / 炎症性骨吸収 / 動脈硬化 / 歯周免疫機能学 / 泡沫化細胞 / アテローム性動脈硬化 / Porphylomonas gingivalis / Fusobacterium nucleatum / Aggregatibacter actinomycetemcomitans / Nucleotide-binding oligomerization / NOD2 / NOD1 / 歯肉緑下プラーク / 歯周疾患活動性 / ノックアウトマウス / TNF受容体 / TNF / 免疫組織学的研究 / 免疫学的研究 / 難治性歯周炎 / 成人性歯周炎 / 補体制御因子 / 骨原性細胞 / 埋没材 / コンポジットレジン用フィラ- / レジン床改良 / ゾル-ゲル法 / ガラスセラミックス / 生体材料 / ALP活性 / MC3T3ーE1細胞 / アルカリフォスファターゼ / 石灰化 / βーTCP Less
  • Research Projects

    (44 results)
  • Research Products

    (185 results)
  • Co-Researchers

    (45 People)
  •  Inflammasome activation by dental calculus and prevention of periodontal tissue destruction using inflammasome inhibitor

    • Principal Investigator
      YOSHIMURA Atsutoshi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Nagasaki University
  •  Study of the role of osteocytes in the occlusal trauma

    • Principal Investigator
      UKAI Takashi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Nagasaki University
  •  Elucidation of periodontitis onset mechanism based on C1q and Wnt signaling

    • Principal Investigator
      Yoshinaga Yausnori
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Fukuoka Dental College
  •  Experimental pathological study on prevention of periodontitis and periimplantitis caused by drugsPrincipal Investigator

    • Principal Investigator
      HARA Yoshitaka
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Nagasaki University
  •  The role of capases in clearance of periodontal pathogens and regulation of inflammatory responses.

    • Principal Investigator
      Kaneko Takashi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Fukuoka Dental College
  •  Basic research for analysis of occlusal trauma mechanism using in vitro osteoclastogenesis assay

    • Principal Investigator
      UKAI Takashi
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Nagasaki University
  •  Relationship between periodontal infection and HIV infection in Kenya using simultaneous microsphere-based multiplex assays

    • Principal Investigator
      NAKAYAMA Koji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  Basic study on the regulation of inflammation of periodontal tissue by targeting Toll-like receptor 4

    • Principal Investigator
      YOSHIMURA Atsutoshi
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  An experimental study of mechanism of periodontal and peri-implant tissue destruction.Principal Investigator

    • Principal Investigator
      HARA Yoshitaka
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  Basic study on periodontal destruction by new T cell subset Th17

    • Principal Investigator
      OZAKI Yukio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  The regulation of periodontal inflammation based on the inflammasomes activated by periodontal pathogens.

    • Principal Investigator
      KANEKO Takashi
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Fukuoka Dental College
      Nagasaki University
  •  Development of multi-layered stem cell sheet transplant materialfor periodontal regenerative therapy

    • Principal Investigator
      ABE Tatsuya
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  Analysis an accelerative mechanism of atherosclerosis by periodontitis-effect of inflammatory alveolar bone resorption-

    • Principal Investigator
      UKAI Takashi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  Evaluation of the periodontal disease activity measuring the ability of dental plaque to activate innate immune system

    • Principal Investigator
      YOSHIMURA Atsutoshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  Biological responses that eliminate invasive bacteria in the periodontal cells

    • Principal Investigator
      KANEKO Takashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  A study on acceleration of bone resorption by immunized cellsPrincipal Investigator

    • Principal Investigator
      HARA Yoshitaka
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  Elucidation of 3D cell growth and its applications for periodontal regeneration therapy

    • Principal Investigator
      ABE Tatsuya
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  Analysis of the mechanism for a periodontopathic bacteria P. gingivalis to escape from innate immune system

    • Principal Investigator
      YOSHIMURA Atsutoshi
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  A basic research on coupling factors between bone resorption and bone formationPrincipal Investigator

    • Principal Investigator
      HARA Yoshitaka
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  The development of periodontal ligament substitutes of fibroblast sheets and their applications for periodontal regenerative therapy

    • Principal Investigator
      ABE Tatsuya
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  Comprehensive analysis of bone formation and its application

    • Principal Investigator
      YAMAGUCHI Akira
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
      Nagasaki University
  •  Immunohistlogical study of mouse periodontal burst modelPrincipal Investigator

    • Principal Investigator
      HARA Yoshitaka
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      NAGASAKI University
  •  炎症性サイトカイン関連遺伝子変異マウスを用いて歯周組織破壊と再生の機序を解析する

    • Principal Investigator
      YAMAGUCHI Akira
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Nagasaki University
  •  難治性歯周炎の細菌学的および免疫学的病態解析ならびにその治療法への応用

    • Principal Investigator
      KATO Ihachi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  Function of cementblast: I vitro study and histopathological studyPrincipal Investigator

    • Principal Investigator
      HARA Yoshitaka
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nagasaki University
  •  Immunohistological study on infiltration of periodontopathic bacterial lipopolysaccharide into gingiva and lesional lymph node.

    • Principal Investigator
      KATO Ihachi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Nagasaki University
  •  A study for establishment of judging periodontal disease activityPrincipal Investigator

    • Principal Investigator
      HARA Yoshitaka
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Nagasaki University
  •  The study of the infection route of periodontopathic bacteria to implants and the time of infection.

    • Principal Investigator
      TANI Masahiko, 長田 豊
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Nagasaki University
  •  Histopathological study with in situ hybridization on cytokine producing cells in bone ersorption

    • Principal Investigator
      KATO Ihachi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Nagasaki University
  •  Experimental study of the effect of T cell on alveolar bone resorption induced by bacterial endotoxinPrincipal Investigator

    • Principal Investigator
      HARA Yoshitaka
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Nagasaki University
  •  A study on possible roles of granulocyte neutral proteinases and the control mechanism of their activities in the process of periodontal breakdown

    • Principal Investigator
      KUNIMATSU Kazushi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Nagasaki University
  •  Immunohistological study on immnological activity of P.gingivalis LPS -Effects on immne cells in vitro and in vivo-

    • Principal Investigator
      KATO Ihachi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Nagasaki University
  •  Comparison between mRNA expression by RT-PCR method in human gingiva of periodontitis and clinical finding

    • Principal Investigator
      TAKAHASHI Hiroshi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Nagasaki University
  •  生体機能性ファイン材料の創成・成体との相互作用及び臨床応用

    • Principal Investigator
      青野 正男
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  Immunohistological study of immune system associated with periodontal tissue breakdown by endotoxin

    • Principal Investigator
      KATO Ihachi
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Nagasaki University
  •  Comparison between phenotyping of immunocompetent cells in the gingiva with periodontitis and clinical behavior

    • Principal Investigator
      TAKAHASHI H
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Nagasaki University
  •  Immunoelectron Microscopic Study on Cytoskelcton of Pocket Epithelium and Infiltrating CellsPrincipal Investigator

    • Principal Investigator
      HARA Yoshitaka
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Nagasaki University
  •  生体機能性ファイン材料の創成・生体との相互作用及び臨床応用

    • Principal Investigator
      AONO Masao
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  生体機能性ファイン材料の創成・生体との相互作用及び臨床応用

    • Principal Investigator
      青野 正男
    • Project Period (FY)
      1987 – 1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Asahi University
  •  生体機能性ファイン材料の創成・主体との相互作用及び臨床応用

    • Principal Investigator
      青野 正男
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  生体機能性ファイン材料の創成・生体との相互作用及び臨床応用

    • Principal Investigator
      青野 正男
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  An experimental study on histopathological changes of alveolar bone around hydroxyapatite during orthodontic tooth movement.Principal Investigator

    • Principal Investigator
      HARA Yoshitaka, 古川 猛士
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Kyushu University
  •  Biological activity of bacterial components in the pathogenesis of periodontal disease

    • Principal Investigator
      AONO Masao
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Conservative dentistry
    • Research Institution
      Kyushu University
  •  The biological activity of inflammatory cells in the pathogenesis of periodontal kisease

    • Principal Investigator
      MAEDA KATSUMASA
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Kyushu University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] ザ・ペリオドントロジー 第2版2014

    • Author(s)
      吉村篤利、原宜興
    • Total Pages
      279
    • Publisher
      永末書店
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Book] エンドトキシン・自然免疫研究 162013

    • Author(s)
      吉村篤利、佐藤佳昌、金子高士、原宜興
    • Total Pages
      39
    • Publisher
      医学図書出版株式会社
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Book] エンドトキシン・自然免疫研究16, 自然免疫から自然炎症へ2013

    • Author(s)
      吉村篤利、佐藤佳昌、金子高士、原宜興
    • Publisher
      医学図書出版株式会社
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Journal Article] Topical application of glycyrrhetinic acid in the gingival sulcus inhibits attachment loss in lipopolysaccharide-induced experimental periodontitis in rats2018

    • Author(s)
      Takamori A.、Yoshinaga Y.、Ukai T.、Nakamura H.、Takamori Y.、Izumi S.、Shiraishi C.、Hara Y.
    • Journal Title

      Journal of Periodontal Research

      Volume: 1 Issue: 3 Pages: 1-1

    • DOI

      10.1111/jre.12529

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K11395, KAKENHI-PROJECT-15K11396, KAKENHI-PROJECT-15K11394
  • [Journal Article] T cell and periosteum cooperation in osteoclastogenesis induced by lipopolysaccharide injection in transplanted mouse tibia2018

    • Author(s)
      Kobayashi Hiroki、Ukai Takashi、Shiraishi Chiaki、Ozaki Yukio、Yoshimura Atsutoshi、Hara Yoshitaka
    • Journal Title

      Journal of Dental Sciences

      Volume: 13 Issue: 3 Pages: 226-233

    • DOI

      10.1016/j.jds.2018.03.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Journal Article] Crystalline structure of pulverized dental calculus induces cell death in oral epithelial cells2018

    • Author(s)
      Ziauddin S M、Yoshimura A、Montenegro Raudales J L、Ozaki Y、Higuchi K、Ukai T、Kaneko T、Miyazaki T、Latz E、Hara Y
    • Journal Title

      Journal of Periodontal Research

      Volume: - Issue: 3 Pages: 353-361

    • DOI

      10.1111/jre.12520

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11836, KAKENHI-PROJECT-15K11015, KAKENHI-PROJECT-26463138, KAKENHI-PROJECT-18K09615
  • [Journal Article] Analysis of access of instrument to root in the skill evaluation of student2017

    • Author(s)
      鵜飼 孝、中村 弘隆、吉永 泰周、高森 明子、尾崎 幸生、白石 千秋、吉村 篤利、原 宜興
    • Journal Title

      Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)

      Volume: 59 Issue: 3 Pages: 172-178

    • DOI

      10.2329/perio.59.172

    • NAID

      130006105727

    • ISSN
      0385-0110, 1880-408X
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Journal Article] Site-level progression of periodontal disease during a follow-up period2017

    • Author(s)
      Nomura Yoshiaki、Yoshimura Atsutoshi、Hara Yoshitaka、Nakamura Toshiaki、Noguchi Kazuyuki、Kakuta Erika、Hanada Nobuhiro、Takashiba Shogo、Amitani Yasuharu、Yoshie Hiromasa、他
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 12 Pages: e0188670-e0188670

    • DOI

      10.1371/journal.pone.0188670

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11836, KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-17K12030, KAKENHI-PROJECT-15H05036, KAKENHI-PROJECT-26463132
  • [Journal Article] Assessing the progression of chronic periodontitis using subgingival pathogen levels: a 24-month prospective multicenter cohort study.2017

    • Author(s)
      Kakuta E, Nomura Y, Morozumi T, et al.
    • Journal Title

      BMC Oral Health.

      Volume: 17 Issue: 1 Pages: 46-46

    • DOI

      10.1186/s12903-017-0337-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26463143, KAKENHI-PROJECT-16K11836, KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-26463132
  • [Journal Article] Role of inflammasome in periodontal tissue2017

    • Author(s)
      吉村 篤利、樋口 賀奈子、原 宜興
    • Journal Title

      Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)

      Volume: 59 Issue: 2 Pages: 57-62

    • DOI

      10.2329/perio.59.57

    • NAID

      130005858793

    • ISSN
      0385-0110, 1880-408X
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Journal Article] Analysis of the ability of subgingival plaque to stimulate Toll-like receptor (TLR)2 and TLR42016

    • Author(s)
      Ziauddin SM, Montenegro RJL, Sato K, Yoshioka H, Ozaki Y, Kaneko T, Yoshimura A, Hara Y
    • Journal Title

      Journal of Periodontology

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Journal Article] Analysis of the ability of sub gingival plaque to stimulate toll-like receptor (TLR) 2 and TLR4.2016

    • Author(s)
      Ziauddin S. M, Jorge L. Montenegro, Kayo Sato, Hidenobu Yoshioka, Yukio Ozaki, Takashi Kaneko, Atsutoshi Yoshimura, Yoshitaka Hara
    • Journal Title

      Journal of Periodontology

      Volume: 00

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Journal Article] Salivary pathogen and serum antibody to assess the progression of chronic periodontitis: a 24-mo prospective multicenter cohort study2016

    • Author(s)
      Morozumi T, Nakagawa T, Nomura Y, Sugaya T, Kawanami M, Suzuki F, Takahashi K, Abe Y, Sato S, Makino-Oi A, Saito A, Takano S, Minabe M, Nakayama Y, Ogata Y, Kobayashi H, Izumi Y, Sugano N, …., Yoshimura A, Hara Y, ….
    • Journal Title

      Journal of Periodontal Research

      Volume: 印刷中 Issue: 6 Pages: 768-778

    • DOI

      10.1111/jre.12353

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24593126, KAKENHI-PROJECT-25463229, KAKENHI-PROJECT-25293424, KAKENHI-PROJECT-26463143, KAKENHI-PROJECT-16K11836, KAKENHI-PROJECT-26463132
  • [Journal Article] The histopathological comparison on the destruction of the periodontal tissue between normal junctional epithelium and long junctional epithelium2016

    • Author(s)
      Noguchi S, Ukai T, Kuramoto A, Yoshinaga Y, Nakamura H, Takamori Y, Yamashita Y, Hara Y
    • Journal Title

      Journal of Periodontal Research

      Volume: 印刷中 Issue: 1 Pages: 74-82

    • DOI

      10.1111/jre.12370

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24593126, KAKENHI-PROJECT-15K11394
  • [Journal Article] Histopathological comparison of the onset of peri-implantitis and periodontitis in rats2016

    • Author(s)
      Yuzo Takamori, Ikiru Atsuta, Hirotaka Nakamura, Takashi Sawase, Kiyoshi Koyano, Yoshitaka Hara
    • Journal Title

      Clinical Oral Implant Research

      Volume: 27 Pages: 1-8

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24593127
  • [Journal Article] Dental Calculus Stimulates Interleukin-1β Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes.2016

    • Author(s)
      Montenegro Raudales JL, Yoshimura A, Sm Z, Kaneko T, Ozaki Y, Ukai T, Miyazaki T, Latz E, Hara Y
    • Journal Title

      PLoS One

      Volume: 11 Issue: 9 Pages: e0162865-e0162865

    • DOI

      10.1371/journal.pone.0162865

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11836, KAKENHI-PROJECT-26463138
  • [Journal Article] Histopathological comparison of the onset of peri-implantitis and periodontitis in rats2016

    • Author(s)
      Takamori Y, Atsuta I, Nakamura H, Sawase T, Koyano K, Hara Y
    • Journal Title

      Clinical Oral Implants Research

      Volume: 印刷中 Issue: 2 Pages: 163-170

    • DOI

      10.1111/clr.12777

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Journal Article] Analysis of the ability of subgingival plaque to stimulate Toll-like receptor (TLR)2 and TLR42016

    • Author(s)
      Ziauddin SM, Montenegro Raudales JL, Sato K, Yoshioka H, Ozaki Y, Kaneko T, Yoshimura A, Hara Y
    • Journal Title

      J. Periodontol.

      Volume: 87 Issue: 9 Pages: 1083-1091

    • DOI

      10.1902/jop.2016.150573

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11836, KAKENHI-PROJECT-26463138
  • [Journal Article] T Cells Are Not Crucial in Bone Resorption in Response to Traumatic Occlusion2015

    • Author(s)
      中村弘隆, 鵜飼 孝, 吉永泰周, 白石千秋, 吉永美穂, 吉村篤利, 原 宜興
    • Journal Title

      The Japanese Journal of Conservative Dentistry

      Volume: 58 Issue: 1 Pages: 35-41

    • DOI

      10.11471/shikahozon.58.35

    • NAID

      130005005974

    • ISSN
      0387-2343, 2188-0808
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Journal Article] 37.RANKL pretreatment plays an important role in the differentiation of pit-forming osteoclasts induced by TNF-α on murine bone marrow macrophages.2015

    • Author(s)
      Yamashita Y, Ukai T, Nakamura H, Yoshinaga Y, Kobayashi H, Takamori Y, Noguchi S, Yoshimura A, Hara Y
    • Journal Title

      Arch Oral Biol.

      Volume: 60(9) Issue: 9 Pages: 1273-1282

    • DOI

      10.1016/j.archoralbio.2015.06.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25463220, KAKENHI-PROJECT-24593126
  • [Journal Article] The Effect of Gram-positive or -negative Bacteria Homogenates on Periodontal Tissue of Immunized Rats2014

    • Author(s)
      吉永泰周,長野史子,金子高士,鵜飼孝,吉村篤利,尾崎幸生,吉永美穂,白石千秋,中村弘隆,藏本明子,高森雄三,野口惠司,山下恭德,泉聡史,原宜興
    • Journal Title

      The Japanese Journal of Conservative Dentistry

      Volume: 57 Issue: 2 Pages: 154-161

    • DOI

      10.11471/shikahozon.57.154

    • NAID

      130004669776

    • ISSN
      0387-2343, 2188-0808
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23593066, KAKENHI-PROJECT-24593126
  • [Journal Article] Nakatsu S, Yoshinaga Y, Kuramoto A, Nagano F, Ichimura I, Oshino K, Yoshimura A, Yano Y, Hara Y2014

    • Author(s)
      Nakatsu S, Yoshinaga Y, Kuramoto A, Nagano F, Ichimura I, Oshino K, Yoshimura A, Yano Y, Hara Y
    • Journal Title

      Journal of Periodontal Research

      Volume: 49 Issue: 3 Pages: 314-322

    • DOI

      10.1111/jre.12109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24593126, KAKENHI-PROJECT-24890169, KAKENHI-PROJECT-26861820
  • [Journal Article] ROCK inhibitor Y-27632 maintains the proliferation of confluent human messenchymal stem cells.2014

    • Author(s)
      Nakamura K, Yoshimura A, Kaneko T, Sato K, Hara Y.
    • Journal Title

      J Periodontal Res

      Volume: 49 Issue: 3 Pages: 363-370

    • DOI

      10.1111/jre.12114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593066, KAKENHI-PROJECT-24593126
  • [Journal Article] Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction.2013

    • Author(s)
      Nagano F, Kaneko T, Yoshinaga Y, Ukai T, Kuramoto A, Nakatsu S, Oshino K, Ichimura I, Hara Y.
    • Journal Title

      Journal of Periodontal Research

      Volume: 48 Issue: 4 Pages: 420-427

    • DOI

      10.1111/jre.12021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593066, KAKENHI-PROJECT-24890169
  • [Journal Article] Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction2013

    • Author(s)
      Fumiko Nagano , Takashi Kaneko, Yasunori Yoshinaga, Takashi Ukai, Akiko Kuramoto, Susumu Nakatsu, Kazushi Oshino, Ikuhisa Ichimura, Yoshitaka Hara
    • Journal Title

      Journal of Periodontal Research

      Volume: 48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24593127
  • [Journal Article] Topical application of lipopolysaccharide into gingival sulcus promotes periodontal destruction in rats immunized with lipopolysaccharide.2012

    • Author(s)
      Yoshinaga Y, Ukai T, Kaneko T, Nakatsu S, Shiraishi C, Kuramoto A, Oshino K, Ichimura I, Hara Y.
    • Journal Title

      Journal of Periodontal Research

      Volume: 47 Pages: 674-680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Journal Article] A single nucleotide polymorphism in 3’-untranslated region contributes to the regulation of Toll-like receptor 4 translation.2012

    • Author(s)
      Sato K, Yoshimura A. Kaneko T, Ukai T, Ozaki Y, Nakamura H, Li X, Matsumura H, Hara Y, Ogata Y.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 287 Pages: 25163-25172

    • NAID

      120006985653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Journal Article] Peptidoglycan and lipopolysaccharide synergistically enhance bone resorption and osteoclastogenesis2012

    • Author(s)
      Kishimoto T, Kaneko T, Ukai T, Yokoyama M, Ayon Haro R, Yoshinaga Y, Yoshimura A, Hara Y.
    • Journal Title

      J Periodontal Res

      Volume: 47 Issue: 4 Pages: 446-454

    • DOI

      10.1111/j.1600-0765.2011.01452.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592627, KAKENHI-PROJECT-24593126
  • [Journal Article] The formation of immune complexes is involved in the acute phase of periodontal destruction in rats.2012

    • Author(s)
      Kuramoto A, Yoshinaga Y, Kaneko T, Ukai T, Shiraishi C, Oshino K, Ichimura I, Hara Y.
    • Journal Title

      Journal of Periodontal Research

      Volume: 47 Pages: 455-462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Journal Article] A single nucleotide polymorphism in 3'-untranslated region contributes to the regulation of Toll-like receptor 4 translation.2012

    • Author(s)
      Sato K, Yoshimura A, Kaneko T, Ukai T, Ozaki Y, Nakamura H, Li X, Matsumura H, Hara Y, Ogata Y
    • Journal Title

      Journal of Biological Chemistry

      Volume: 287 Issue: 30 Pages: 25163-72512

    • DOI

      10.1074/jbc.m111.338426

    • NAID

      120006985653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Journal Article] テーパード毛歯ブラシの臨床効果に関する研究2012

    • Author(s)
      吉永美穂、鵜飼孝、吉永泰周、白石千秋、金子高士、岸本隆明、佐藤佳昌、吉村篤利、原宜興
    • Journal Title

      日本歯科保存学雑誌

      Volume: 55 Pages: 158-164

    • NAID

      110009479992

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Journal Article] Peptidoglycan and lipopolysaccharide synergistically enhance bone resorption and osteoclastogenesis.2012

    • Author(s)
      Kishimoto T, Kaneko T, Ukai T, Yokoyama M, Ayon Haro R, Yoshinaga Y, Yoshimura A, Hara Y.
    • Journal Title

      Journal of Periodontal Research

      Volume: 47 Pages: 446-454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Journal Article] テーパード毛歯ブラシの臨床効果に関する研究2012

    • Author(s)
      吉永美穂、鵜飼孝、吉永泰周、白石千秋、金子高士、岸本隆明、佐藤佳昌、吉村篤利、原宜興
    • Journal Title

      歯科保存学会会誌

      Volume: 55 Pages: 158-164

    • NAID

      110009479992

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Journal Article] Membrane-bound CD40 Ligand on T cells from mice injected with lipopolysaccharide(LPS) accelerates LPS-induced osteoclastogenesis2011

    • Author(s)
      M Yokoyama, T Ukai, E. R. Ayon Haro, T Kishimoto, Y Yoshinaga, Y Hara
    • Journal Title

      Journal of Periodontal Research,

      Volume: 46 Pages: 464-474

    • Data Source
      KAKENHI-PROJECT-21592627
  • [Journal Article] Locally administered interferon-γaccelerates lipopolysaccharide-induced osteoclastogenesis independent of immunohistological RANKL upregulation E2011

    • Author(s)
      R. Ayon Haro, T Ukai, M Yokoyama, T Kishimoto, Y Yoshinaga, Y Hara
    • Journal Title

      Journal of Periodontal Research

      Volume: 46 Pages: 361-373

    • Data Source
      KAKENHI-PROJECT-21592627
  • [Journal Article] Green tea catechin inhibits lipopolysaccharide-induced bone resorption in vivo2010

    • Author(s)
      Hirotaka Nakamura, Takashi Ukai, Atsutoshi Yoshimura, Yoshio Kozuka, Hidenobu Yoshioka, Yasunori Yoshinaga, Yoshihiro Abe, Yoshitaka Hara
    • Journal Title

      Journal of Periodontal Research 45

      Pages: 23-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592431
  • [Journal Article] NOD1 and NOD2 Mediate Sensing of Periodontal Pathogens2010

    • Author(s)
      Tsuyoshi Okugawa, Takashi Kaneko, Atsutoshi Yoshimura, Neal Silverman, Yoshitaka Hara
    • Journal Title

      Journal of Dental Research 89

      Pages: 186-191

    • URL

      http://naosite.1b.nagasaki-u.ac.jp/dspace/bitstream/10069/24668/1/JDR89_186.pdf

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592431
  • [Journal Article] NOD1 and NOD2 Mediate Sensing of Periodontal Pathogens.2010

    • Author(s)
      Okugawa T, Kaneko T, Yoshimura A, Silverman N, Hara Y.
    • Journal Title

      J Dent Res 89(2)

      Pages: 186-191

    • Data Source
      KAKENHI-PROJECT-20592432
  • [Journal Article] Recombinant Porphyomonas gingivalis FimA preproprotein expressed in Escherichia coil is a lipoprotein and recombinant FimA processed protein is auto-polymerized in vitro2010

    • Author(s)
      Mikio Shoji, Atsutoshi Yoshimura, Hidenobu Yoshioka, Akemi Takade, Yasuko Takuma, Hideharu Yukitake, Mariko Naito, Yoshitaka Hara, Shin-Ichi Yoshida, Koji Nakayama
    • Journal Title

      Canadian Journal of Microbiology 56

      Pages: 959-967

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592431
  • [Journal Article] Activity of Supragingival Plaque to Induce Toll-Like Receptor 4-Mediated Stimulation is Associated with Cytokine Production by Peripheral Blood Mononuclear Cells2009

    • Author(s)
      Ryusuke Yamaguchi, Atsutoshi Yoshimura, Hidenobu Yoshioka, Takashi Kaneko, Yoshitaka Hara
    • Journal Title

      Journal of Periodontology 79

      Pages: 512-520

    • NAID

      130004571075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592431
  • [Journal Article] Relationship between periodontal status and HbAlc in non-diabetics2009

    • Author(s)
      Hideaki Hayashida Koji Kawasaki, Atsutoshi Yoshimura, Noboru Takamura, Yoshitaka Hara, Takahiro Maeda, Toshiyuki Saito
    • Journal Title

      Journal of Public Health Dentistry 69

      Pages: 204-206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592431
  • [Journal Article] Locally administered T cells from mice immunized with lipopolysaccharide (LPS) accelerate LPS-induced bone resorption2009

    • Author(s)
      Ozaki Y, Ukai T, Yamaguchi M, Yokoyama M, Ayon Haro ER, Kaneko T, Yoshinaga M, Nakamura H, Shiraishi C, Hara Y
    • Journal Title

      Bone, (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592389
  • [Journal Article] Cyclosporin A and phenytoin modulate inflammatory responses.2009

    • Author(s)
      Suzuki AMM, Yoshimura A, Ozaki Y, Kaneko T, Hara Y.
    • Journal Title

      J Dent Res 88(12)

      Pages: 1131-1136

    • Data Source
      KAKENHI-PROJECT-20592432
  • [Journal Article] Identification of a Gingipain-Sensitive Surface Ligand of Porphyromonas gingivalis That Induces Toll-Like Receptor 2- and 4-Independent NF-κB Activation in CHO Cells2009

    • Author(s)
      Koki Haruyama, Atsutoshi Yoshimura, Mariko Naito, Mami Kishimoto, Mikio Shoji, Yoshimitsu Abiko, Yoshitak Hara, Koji Nakayama
    • Journal Title

      Infection and Immunity 77

      Pages: 4414-4420

    • URL

      http://naosite.1b.nagasaki-u.ac.jp/dspace/bitstream/10069/23135/1/InfImm77_4414.pdf

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592431
  • [Journal Article] Locally administered T cells from mice immunized with lipopolysaccharide (LPS) accelerate LPS-induced bone resorption.2009

    • Author(s)
      Ozaki Y, Ukai T, Yamaguchi M, Yokoyama M, Haro ER, Yoshimoto M, Kaneko T, Yoshinaga M, Nakamura H, Shiraishi C, Hara Y.
    • Journal Title

      Bone 44(6)

      Pages: 1169-1176

    • Data Source
      KAKENHI-PROJECT-20592432
  • [Journal Article] Activity of supragingival plaque to induce Toll-like receptor 4-mediated stimulation is associated with cytokine production by peripheral blood mononuclear cells.2009

    • Author(s)
      Yamaguchi R, Yoshimura A, Yoshioka H, Kaneko T, Hara Y.
    • Journal Title

      J Periodontol 80(3)

      Pages: 512-520

    • NAID

      130004571075

    • Data Source
      KAKENHI-PROJECT-20592432
  • [Journal Article] Cyclosporin A and Phenytoin Modulate Inflammatory Responses2009

    • Author(s)
      Ana Maria M.Suzuki, Atsutoshi Yoshimura, Yokio Ozaki, Takashi Kaneko, Yoshitaka Hara
    • Journal Title

      Journal of Dental Research 88

      Pages: 1131-1136

    • URL

      http://naosite.1b.nagasaki-u.ac.jp/dspace/bitstream/10069/24540/1/JDR88_1131.pdf

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592431
  • [Journal Article] グリチルレチン酸はLPS誘導性骨吸収を抑制する2008

    • Author(s)
      中村弘隆, 鵜飼孝, 吉永泰周, 尾崎幸生, 金子高士, 白石千秋, 岸本真実, 小野山美穂, 阿部嘉裕, 安部達也, 吉村篤利, 原宜興
    • Journal Title

      日本歯科保存学雑誌 51

      Pages: 323-330

    • NAID

      110007151238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592431
  • [Journal Article] Lack of Toll-like receptor 4 decreases lipopolysaccharide-induced bone resorption in C3H/HeJ mice in vivo2008

    • Author(s)
      Hirotaka Nakamura, Yukiko Fukusaki, Atsutoshi Yoshimura, Chiaki Shiraishi, Mami Kishimoto, Takashi Kaneko, Yoshitaka Hara
    • Journal Title

      Oral Microbiology and Immunology 23

      Pages: 190-195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592431
  • [Journal Article] Analysis of the activity to induce TLR2- and TLR4-mediaed stimulation of supragingival plaque2008

    • Author(s)
      Yoshioka H, Yoshimura A, Kaneko T, Golenbock DT, Hara Y.
    • Journal Title

      J Periodontol 79(5)

      Pages: 920-928

    • Data Source
      KAKENHI-PROJECT-20592432
  • [Journal Article] グリチルレチン酸はLPS誘導性骨吸収を抑制する2008

    • Author(s)
      中村弘隆、鵜飼孝、吉永泰周、尾崎幸生、金子高士、白石千秋、岸本真実、小野山美穂、阿部嘉裕、安部達也、吉村篤利、原宜興
    • Journal Title

      日本歯科保存学雑誌 51(3)

      Pages: 323-330

    • NAID

      110007151238

    • Data Source
      KAKENHI-PROJECT-20592432
  • [Journal Article] Analysis of the Activity to Induce TLR2- and TLR4-Mediated Stimulation of Supragingival Plaque2008

    • Author(s)
      Hidenobu Yoshioka, Atsutoshi Yoshimura, Takashi Kaneko, Douglas T.Golenbock, Yoshitaka Hara
    • Journal Title

      Journal of Periodontology 23

      Pages: 920-928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592431
  • [Journal Article] T cells are able to promote lipopolysaccharide-induced bone resorption in mice in the absence of B cells.2008

    • Author(s)
      Yamaguchi M, Ukai T, Kaneko T, Yoshinaga M, Yokoyama M, Ozaki Y, Hara Y.
    • Journal Title

      J Periodontal Res 43(5)

      Pages: 549-555

    • NAID

      120006982397

    • Data Source
      KAKENHI-PROJECT-20592432
  • [Journal Article] T cells areable to promote lipopolysaccharide-induced bone resorption in mice in the absence of B cells2008

    • Author(s)
      Yamaguchi M, Ukai T, Kaneko T, Yoshinaga M, Yokoyama M, Ozaki Y, Hara Y
    • Journal Title

      J Periodontal Res 43 (5)

      Pages: 549-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592389
  • [Journal Article] Lack of Toll-like receptor 4 decreases lipopolysaccharide-induced bone resorption in C3H/HeJ mice in vivo.2008

    • Author(s)
      Nakamura H, Fukusaki Y, Yoshimura A, Shiraishi C, Kishimoto M, Kaneko T, Hara Y.
    • Journal Title

      Oral Microbiol Immunol 23(3)

      Pages: 190-195

    • Data Source
      KAKENHI-PROJECT-20592432
  • [Journal Article] Regulation of osteoclast differentiation and function by the CaMK/CREB pathway.2007

    • Author(s)
      Sato K, Suematsu A, Nakashima T, Takemoto- Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H, Takayanagi H
    • Journal Title

      Nat Med 12

      Pages: 1410-1416

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104015
  • [Journal Article] Regulation of osteoclast differentiation and function by the CaMK/CREB pathway.2007

    • Author(s)
      Sato K, Suematsu A, Nakashima T, Takemoto-Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H, Takayanagi H
    • Journal Title

      Nat Med 12

      Pages: 1410-1416

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104015
  • [Journal Article] B cell play an important role in lipopolysaccharide-induced bone resorption2006

    • Author(s)
      Yoshio Kozuka, Yukio Ozaki, Takashi Ukai, Takashi Kaneko, Yoshitaka Hara
    • Journal Title

      Calcified Tissue International. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16592072
  • [Journal Article] Evaluation of RANKL/RANK/OPG gene polymorphism in aggressive periodontitis.2006

    • Author(s)
      Nurtami S, Robello D, Ishihara U, Noguchi T, Yamaguchi A, Kojima T
    • Journal Title

      J Pepriod Res In press

    • Data Source
      KAKENHI-PROJECT-14104015
  • [Journal Article] LPS誘導型骨吸収におけるRANKLおよびOPGに関する免疫組織学的研究.2005

    • Author(s)
      吉本真弓, 鵜飼 孝, 原 宣興
    • Journal Title

      日本歯科保存学会雑誌 48巻2号

      Pages: 257-265

    • NAID

      10015686404

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16592072
  • [Journal Article] Immunohistological study on expression of receptor activator of NF-κ B ligand and osteoprotegerin in lipopolysaccharide-induced bone resorption2005

    • Author(s)
      Mayumi Yoshimoto, Takashi Ukai, Yoshitaka Hara
    • Journal Title

      Journal of Japanese Conservative Dentistry. 48(2)

      Pages: 257-265

    • NAID

      10015686404

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16592072
  • [Journal Article] Periodontal tissue engineering by transplantation of multilayered sheets of phenotypically modified gingival fibroblasts.

    • Author(s)
      Nakajima, K., Abe, T., Tanaka, M., Hara, Y
    • Journal Title

      Journal of Periodontal Research (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592265
  • [Journal Article] Periodontal tissue engineering by transplantation of multilayered sheets of phenotypically modified gingival fibroblasts

    • Author(s)
      K. Nakajima, T. Abe, M. Tanaka, Y. Hara
    • Journal Title

      Journal of Periodontal Research 印刷中

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592265
  • [Presentation] 歯周病原細菌によるIL‐1βの活性化に対するスルホニル尿素薬の影響2019

    • Author(s)
      河原ゆり, 金子高士, 吉永泰周, 有田陽一, 笠孝成, 中村恵子, 古賀千尋, 吉村篤利, 坂上竜資
    • Organizer
      第62回日本歯周病学会春季学術大会
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] NLRP3インフラマソームは外傷性咬合による骨吸収に関与する2018

    • Author(s)
      有田陽一, 吉永泰周, 金子高士, 河原ゆり, 中村恵子, 古賀千尋, 大城希美子, 山本南奈, 廣松亮, 有田晴一, 坂上竜資
    • Organizer
      第61回秋季日本歯周病学会
    • Data Source
      KAKENHI-PROJECT-15K11394
  • [Presentation] Dental calculus alters the permeability of HSC-2 oral epithelial cell monolayer2018

    • Author(s)
      SM Ziauddin,Atsutoshi Yoshimura,Jorge Luis Montenegro Raudales,Yukio Ozaki,Kanako Higuchi,Takashi Kaneko,Takashi Ukai,Yoshitaka Hara
    • Organizer
      第61回日本歯周病学会春季学術大会
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] 歯石により誘導されるHSC-2口腔上皮細胞の細胞死において結晶構造および菌体成分が果たす役割2017

    • Author(s)
      SM Ziauddin, 吉村篤利, Jorge Luis Montenegro Raudales, 尾崎幸生, 樋口賀奈子, 金子高士, 原宜興
    • Organizer
      平成29年度日本歯周病学会60周年記念京都大会
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] Dental calculus induces pyroptotic cell death in the HSC-2 oral epithelial cell line2017

    • Author(s)
      Ziauddin S M, Yoshimura A, Montenegro Raudales J L, Ozaki Y, Higuchi K, Kaneko T, Hara Y
    • Organizer
      第60回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] 歯石により誘導される HSC-2 口腔上皮細胞の細胞死において結晶構造および菌体成分が果たす役割2017

    • Author(s)
      S M Ziauddin, 吉村 篤利, Montenegro Raudales J.L., 尾崎 幸生, 樋口 賀奈子, 金子 高士, 原 宜興
    • Organizer
      第60回日本歯周病学会春季学術大会
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] Toll-like receptor刺激は酸化LDL受容体Lox-1を介して破骨細胞形成に影響する2017

    • Author(s)
      大城希美子、吉永泰周、金子高士、有田陽一、河原ゆり、有田晴一、笠孝成、山本南奈、村上弘、廣松亮、岡部幸司、坂上竜資
    • Organizer
      平成29年度日本歯周病学会九州五大学・日本臨床歯周病学会九州支部合同研修会
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] アポトーシスが咬合性外傷における骨吸収におよぼす影響に関する病理組織学的研究2017

    • Author(s)
      小山美香,鵜飼 孝,中村弘隆,山下恭徳,小林弘樹,樋口賀奈子,白石千秋,吉村篤利,原 宜興
    • Organizer
      日本歯科保存学会2017年度春季学術大会
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] アポトーシスが咬合性外傷における骨吸収におよぼす影響に関する病理組織学的研究.2017

    • Author(s)
      小山 美香, 鵜飼 孝, 中村 弘隆, 山下 恭徳, 小林 弘樹, 樋口 賀奈子, 白石 千秋, 吉村 篤利, 原 宜興
    • Organizer
      第146回日本歯科保存学会2017年度春季学術大会
    • Data Source
      KAKENHI-PROJECT-16K11837
  • [Presentation] グリブリドは歯周病原細菌による実験的歯周炎を抑制する2017

    • Author(s)
      吉永泰周、金子高士、有田陽一、河原ゆり、有田晴一、笠孝成、中村恵子、吉村篤利、古賀千尋、坂上竜資
    • Organizer
      平成29年度第60回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] 炎症性骨吸収における破骨細胞形成への T 細胞と骨膜構成細胞の関与2017

    • Author(s)
      小林弘樹,鵜飼 孝,中村弘隆,高森(藏本)明子,高森雄三,山下恭徳,泉 聡史,小山美香,白石千秋,吉村篤利,原 宜興
    • Organizer
      日本歯科保存学会2017年度春季学術大会
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] Epigallocatechin gallate inhibits acceleration of osteoclastogenesis by TNFα in vitro.2017

    • Author(s)
      Ukai T, Yamashita Y, Kobayashi H, Oyama M, Yoshimura A, Hara Y
    • Organizer
      International conference on Dentistry and Oral Health, Valencia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] T細胞および骨芽細胞は炎症性骨吸収に関与するー病理組織学的研究ー2017

    • Author(s)
      小林弘樹, 鵜飼 孝, 白石千秋, 尾崎幸生, 吉村篤利, 原 宜興
    • Organizer
      平成29年度日本歯周病学会九州五大学・日本臨床歯周病学会九州支部合同研修会
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] グリブリドは歯周病原細菌によるラット実験的歯周炎を抑制する2017

    • Author(s)
      吉永泰周,金子高士,有田陽一,河原ゆり,有田晴一,笠孝成,中村恵子,吉村篤利,古賀千尋,坂上竜資
    • Organizer
      第59回日本歯周病学会春季学術大会
    • Data Source
      KAKENHI-PROJECT-15K11394
  • [Presentation] 外傷性咬合による骨吸収へのRANKLとHMGB-1の関与-病理組織学的研究-2017

    • Author(s)
      小山美香, 鵜飼 孝, 山下恭徳, 小林弘樹, 吉村篤利, 原宜興
    • Organizer
      平成29年度日本歯周病学会九州五大学・日本臨床歯周病学会九州支部合同研修会
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] Hydroxyapatite crystal particles induce cell death in the HSC-2 oral epithelial cell line2017

    • Author(s)
      Ziauddin SM, A. Yoshimura, J L Montenegro Raudales, Y. Ozaki, T. Kaneko, K. Higuchi, C. Shiraishi, A. Kuramoto, Y. Takamori, Y. Yamashita, H. Kobayashi, T. Ukai, Y. Hara
    • Organizer
      16th International Congress of Periodontology of the International Academy of Periodontology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] 外傷性咬合による骨吸収へのRANKLとHMGB-1の関与-病理組織学的研究-2017

    • Author(s)
      小山 美香, 鵜飼 孝, 山下 恭徳, 小林 弘樹, 吉村 篤利, 原 宜興
    • Organizer
      平成29年度日本歯周病学会九州五大学・日本臨床歯周病学会九州支部合同研修会
    • Data Source
      KAKENHI-PROJECT-16K11837
  • [Presentation] グリブリドは歯周病原細菌によるラット実験的歯周炎を抑制する2017

    • Author(s)
      吉永泰周、金子高士、有田陽一、河原ゆり、有田晴一、笠孝成、中村恵子、古賀千尋、佐藤博信、坂上竜資
    • Organizer
      第44回福岡歯科大学学会総会
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] コレステロール結晶はNLRP3インフラマソームを活性化してマウスマクロファージにおけるIL-1β産生と破骨細胞形成を促進する2017

    • Author(s)
      樋口賀奈子, 吉村篤利, 白石千秋, 原 宜興
    • Organizer
      第146回日本歯科保存学会2017年度秋季学術大会
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] グリブリドは歯周病原細菌によるラット実験的歯周炎を抑制する2017

    • Author(s)
      吉永泰周, 金子高士, 有田陽一, 河原ゆり, 有田晴一, 笠孝成, 中村恵子, 吉村篤利, 古賀千尋, 坂上竜資
    • Organizer
      第60回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] Dental calculus activates inflammasome in human oral epithelial cells.2016

    • Author(s)
      SM Z, Montenegro Raudales JL, Ozaki Y, Kaneko T, Yoshimura A, Hara Y
    • Organizer
      第23回日本歯科医学会総会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2016-10-21
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] リポ多糖およびペプチドグリカン局所投与マウス歯槽骨面上の破骨細胞形成において TNF-α が果たす役割2016

    • Author(s)
      尾崎幸生、吉村篤利、金子 高士、鵜飼 孝、山下 恭徳、Montenegro Jorge、 Sm Ziauden、原 宜興
    • Organizer
      平成28年度秋季日本歯周病学会学術大会
    • Place of Presentation
      新潟市
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] 糖尿病治療薬グリブリドは菌体破砕物誘導性ラット実験的歯周炎を抑制する2016

    • Author(s)
      吉永泰周, 金子高士, 有田陽一, 河原ゆり, 有田晴一, 笠孝成, 吉村篤利, 古賀千尋, 坂上竜資
    • Organizer
      平成28年度日本歯周病学会九州五大学日本臨床歯周病学会九州支部合同研修会
    • Place of Presentation
      長崎市
    • Year and Date
      2016-11-06
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] 破骨細胞前駆細胞へのRANKL前刺激はTNFαによる吸収能をもった破骨細胞分化に重要である2016

    • Author(s)
      鵜飼 孝、山下恭徳、原 宜興
    • Organizer
      第23回日本歯科医学会総会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2016-10-21
    • Data Source
      KAKENHI-PROJECT-25463220
  • [Presentation] RANKL前刺激を受けた破骨細胞前駆細胞はTNF-αにより吸収能をもった破骨細胞に分化する2016

    • Author(s)
      鵜飼孝, 山下恭德, 原 宜興
    • Organizer
      歯科医学会総会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2016-10-21
    • Data Source
      KAKENHI-PROJECT-25463220
  • [Presentation] Dental calculus triggers NLRP3 inflammasome-dependent IL-1beta secretion in mouse macrophages.2016

    • Author(s)
      Jorge Luis Montenegro Raudales, A Yoshimura, SM Ziauddin, T Kaneko, Y. Ozaki, T, Ukai, T. Miyazaki, E. Latz, Y. Hara.
    • Organizer
      14th Biennial Meeting International Endotoxin and Innate Immunity Society
    • Place of Presentation
      Hambrug
    • Year and Date
      2016-09-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] Relationships between the ability of subgingival plaque to stimulate Toll-like receptor 4 and periodontal conditions2016

    • Author(s)
      SM Z, Montenegro Raudales JL, Sato K, Yoshioka H, Ozaki Y, Kaneko T, Yoshimura A, Hara Y
    • Organizer
      第59回春季日本歯周病学会学術大会
    • Place of Presentation
      かごしま県民交流センター(鹿児島県・鹿児島市)
    • Year and Date
      2016-05-20
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] Dental calculus triggers NLRP3 inflammasome-dependent IL-1β secretion in mouse macrophages.2016

    • Author(s)
      Montenegro Raudales JL, Yoshimura A, SM Z, Kaneko T, Ozaki Y, Ukai T, Miyazaki T, Latz E, Hara Y
    • Organizer
      he 14th Biennial Meeting of the International Endotoxin and Innate Immunity Society
    • Place of Presentation
      Curio Haus (Hamburg, Germany)
    • Year and Date
      2016-09-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] Dental calculus activates inflammasome in human oral epithelial cells.2016

    • Author(s)
      Jorge Montenegro, Atsutoshi Yoshimura, SM Ziauddin, Takashi Kaneko, Yukio Ozaki, Toshihiro Miyazaki, Takashi Ukai, Eicke Latz, Yoshitaka Hara.
    • Organizer
      第23回日本歯科医学会総会
    • Place of Presentation
      福岡市
    • Year and Date
      2016-10-21
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] 糖尿病治療薬グリブリドは菌体破砕物誘導性ラット実験的歯周炎を抑制する2016

    • Author(s)
      吉永泰周, 金子高士, 有田陽一, 河原ゆり, 有田晴一, 笠孝成, 吉村篤利, 古賀千尋, 坂上竜資
    • Organizer
      平成28年度日本歯周病学会九州五大学・日本臨床歯周病学会九州支部合同研修会
    • Place of Presentation
      長崎県歯科医師会館(長崎県・長崎市)
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] Dental calculus stimulates IL-1beta release through the NLRP3 inflammasome in human and mouse phagocytes.2016

    • Author(s)
      Jorge Montenegro, Atsutoshi Yoshimura, SM Ziauddin, Takashi Kaneko, Yukio Ozaki, Toshihiro Miyazaki, Takashi Ukai, Eicke Latz, Yoshitaka Hara.
    • Organizer
      第23回日本歯科医学会総会
    • Place of Presentation
      福岡市
    • Year and Date
      2016-10-21
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] Dental calculus stimulates IL-1β release through the NLRP3 inflammasome in human and mouse phagocytes.2016

    • Author(s)
      Montenegro Raudales JL, Yoshimura A, SM Z, Kaneko T, Ozaki Y, Miyazaki T, Ukai T, Latz E, Hara Y
    • Organizer
      第23回日本歯科医学会総会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2016-10-21
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] リポ多糖およびペプチドグリカン局所投与マウス歯槽骨面上の破骨細胞形成においてTNF-α が果たす役割2016

    • Author(s)
      尾崎幸生, 吉村篤利, 金子高士, 鵜飼孝, 山下恭徳, Montenegro Raudales JL, SM Z, 原宜興
    • Organizer
      第59回秋季日本歯周病学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県・新潟市)
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-16K11836
  • [Presentation] 歯石はNLRP3インフラマソームを活性化してヒトおよびマウス貪食細胞によるIL-1β産生を誘導す2015

    • Author(s)
      ホルへ ルイス モンテネグロ、 吉村 篤利、 ジャウディン エスエム、中村 弘隆 、金子 高士、 尾崎 幸生、 原 宜興
    • Organizer
      平成27年度日本歯周病学会九州5大学、日本臨床歯周病学会九州支部合同研修会
    • Place of Presentation
      福岡市
    • Year and Date
      2015-11-08
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] Topical application of glycyrrhetinic acid into rat gingival sulcus inhibits periodontal destruction induced by lipopolisaccharide2015

    • Author(s)
      Takamori A, Yoshinaga Y, Ukai T, Nakamura H, Takamori Y, Yamashita Y, Izumi S, Kobayashi H, Shiraishi C, Hara Y
    • Organizer
      International Academy of Periodontology Meeting
    • Place of Presentation
      Santiago (Chile)
    • Year and Date
      2015-04-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Vascular endothelial cells promotes bone destruction in rat occlusal trauma.2015

    • Author(s)
      Ukai T, Yamashita Y, Nakamura H, Yoshimura A, Hara Y
    • Organizer
      11th APSP meeting
    • Place of Presentation
      Bali, Indonesia
    • Year and Date
      2015-10-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25463220
  • [Presentation] マウス骨髄マクロファージにおいてRANKL前刺激はTNF-a刺激による吸収活性を持つ破骨細胞の分化に重要な役割をはたす2015

    • Author(s)
      山下恭德, 鵜飼孝, 中村弘隆, 小林弘樹, 高森雄三, 野口惠司, 吉村篤利, 原 宜興
    • Organizer
      平成27年度日本歯周病学会九州五大学・日本臨床歯周病学会九州支部合同研修会
    • Place of Presentation
      アクロス福岡(福岡県福岡市)
    • Year and Date
      2015-11-08
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] 歯石は NLRP3インフラマソームを活性化してヒトおよびマウス貪食細胞によるIL-1β産生を誘導する2015

    • Author(s)
      モンテネグロホルヘルイス、吉村篤利、ジャウディンエスエム、中村弘隆, 金子高士, 尾崎幸生, 原宜興
    • Organizer
      平成27年度日本歯周病学会九州五大学・日本臨床歯周病学会九州支部合同研修会
    • Place of Presentation
      アクロス福岡(福岡県福岡市)
    • Year and Date
      2015-11-08
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] ラット実験的歯周炎モデルを用いた歯周炎とインプラント周囲炎の病理組織学的比較2015

    • Author(s)
      髙森雄三, 中村弘隆, 藏本明子, 吉村篤利, 鵜飼 孝, 尾崎幸生, 白石千秋, 山下恭德, 泉 聡史, 小林弘樹, 小山美香, 原 宜興
    • Organizer
      日本歯科保存学会2015年度秋季学術大会
    • Place of Presentation
      文京シビックホール(東京)
    • Year and Date
      2015-11-12
    • Data Source
      KAKENHI-PROJECT-24593127
  • [Presentation] Dental calculus induces IL-1β production through the NLRP3 inflammasome.2015

    • Author(s)
      A.Yoshimura , J.L. Montenegro, S.M. Ziauddin, H. Nakamura, T. Kaneko, Y. Ozaki, Y. Hara
    • Organizer
      Toll2015
    • Place of Presentation
      Marbella, Spain
    • Year and Date
      2015-09-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] Dental calculus induces IL-1β production through the NLRP3 inflammasome2015

    • Author(s)
      Yoshimura A, Montenegro JL, Ziauddin SM, Nakamura H, Kaneko T, Ozaki1 Y, Hara Y
    • Organizer
      Toll 2015
    • Place of Presentation
      Marbella (Spain)
    • Year and Date
      2015-09-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Resveratrol inhibits NLRP3 inflammasome-derived IL-1 beta secretion induced by dental calculus in murine macrophages2015

    • Author(s)
      Jorge Luis Montenegro Raudales,Atsutoshi Yoshimura, Sm Ziauddin, Hirotaka Nakamura, Takashi Kaneko, Yukio Ozaki, Yoshitaka Hara
    • Organizer
      第58回秋季歯周病学会学術大会
    • Place of Presentation
      浜松市
    • Year and Date
      2015-09-12
    • Data Source
      KAKENHI-PROJECT-26463138
  • [Presentation] Histopathological comparison of destruction between peri-implant and periodontal yissue in rats2015

    • Author(s)
      Takamori Y, Takamori A, Yoshinaga Y, Ukai T, Ozaki Y, Shiraishi C, Izumi S, Kobayashi H, Nakamura H, Yoshimura A, Hara Y
    • Organizer
      11th APSP meeting
    • Place of Presentation
      Bali (Indonesia)
    • Year and Date
      2015-10-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] ラット実験的歯周炎モデルを用いた歯周炎とインプラント周囲炎の病理組織学的比較2015

    • Author(s)
      髙森雄三, 中村弘隆, 藏本明子, 吉村篤利, 鵜飼 孝, 尾崎幸生, 白石千秋, 山下恭德, 泉 聡史, 小林弘樹, 小山美香, 原 宜興
    • Organizer
      日本歯科保存学会2015年度秋季学術大会
    • Place of Presentation
      文京シビックホール(東京都文京区)
    • Year and Date
      2015-11-12
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Relationship between a single nucleotide polymorphism in the 3’-untranslated region of TLR4 and periodontal condition2015

    • Author(s)
      Lee H, Yoshimura A, Montenegro RJL, Ziauddin SM, Kuramoto A, Shiraishi C, Ukai T, Hara Y
    • Organizer
      International Academy of Periodontology Meeting
    • Place of Presentation
      Santiago (Chile)
    • Year and Date
      2015-04-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Histopathological Comparison Of Destruction Between Peri-implant And Periodontal Tissue In Rats.2015

    • Author(s)
      Takamori Y, Takamori A, Yoshinaga Y, Ukai T, Ozaki Y, Shiraishi C, Izumi S, Kobayashi H, Nakamura H, Yoshimura A, Hara Y
    • Organizer
      11th Asian Pacific Society of Periodontology meeting
    • Place of Presentation
      Bali, Indonesia
    • Year and Date
      2015-10-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24593127
  • [Presentation] Vascular endothelial cells promotes bone destruction in rat occlusal trauma2015

    • Author(s)
      Ukai T, Yamashita Y, Nakamura H, Yoshimura A, Hara Y
    • Organizer
      11th APSP meeting
    • Place of Presentation
      Bali (Indonesia)
    • Year and Date
      2015-10-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Resveratrol inhibits NLRP3 inflammasome-derived IL-1β secretion induced by dental calculus in murine macrophages2015

    • Author(s)
      モンテネグロホルヘルイス, 吉村篤利, ジャウディンエスエム, 中村弘隆, 金子高士, 尾崎幸生, 原宜興
    • Organizer
      第58回春秋日本歯周病学会学術大会
    • Place of Presentation
      アクトシティ浜松(静岡県浜松市)
    • Year and Date
      2015-09-12
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] マウス骨髄マクロファージにおいてRANKL前刺激はTNF-a刺激による吸収活性を持つ破骨細胞の分化に重要な役割をはたす2015

    • Author(s)
      山下恭德, 鵜飼孝, 中村弘隆, 小林弘樹, 高森雄三, 野口惠司, 吉村篤利, 原 宜興
    • Organizer
      平成27年度日本歯周病学会九州五大学・日本臨床歯周病学会九州支部合同研修会
    • Place of Presentation
      アクロス福岡(福岡県・福岡市)
    • Year and Date
      2015-11-08
    • Data Source
      KAKENHI-PROJECT-25463220
  • [Presentation] ラットにおけるインプラント周囲炎と歯周炎発症の病理組織学的比較2014

    • Author(s)
      高森雄三,熱田 生,吉永泰周,藏本明子,野口惠司,泉 聡史,山下恭德, 鵜飼 孝,吉村篤利,原 宜興
    • Organizer
      日本歯周病学会2014年度秋季学術大会
    • Place of Presentation
      神戸国際展示場(神戸市)
    • Year and Date
      2014-10-19
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Dental calculus induces IL-1β production in murine macrophages through the NLRP3 inflammasome2014

    • Author(s)
      モンテネグロ・ホルヘ、吉村篤利、エスエム・ジャウディン、金子高士、原 宜興
    • Organizer
      日本歯周病学会2014年度秋季学術大会
    • Place of Presentation
      神戸国際展示場(神戸市)
    • Year and Date
      2014-10-19
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Dental calculus induces IL-1β production in murine macrophages through the NLRP3 inflammasome2014

    • Author(s)
      モンテネグロホルヘ、吉村篤利、エスエムジャウディン、金子高士、原宜興
    • Organizer
      第56回秋季歯周病学会学術大会
    • Place of Presentation
      神戸国際展示場(兵庫県・神戸市)
    • Year and Date
      2014-10-19
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] ROCK inhibitor Y-27632 maintains the proliferation ofconfluent human mesenchymal stem cells2013

    • Author(s)
      Kouhei Nakamura, Atsutoshi Yoshimura, Takashi Kaneko, Kayo Sato, Chiaki Shiraishi, Miho Yoshinaga, Hirotaka Nakamura, Yoshitaka Hara
    • Organizer
      10th Asian Pacific Society of Periodontology Meeting
    • Place of Presentation
      奈良県新公会堂(奈良市)
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] 歯肉縁下プラークのToll-like receptor (TLR) 2およびTLR4活性化能と歯周組織の状態との関連性について2013

    • Author(s)
      佐藤佳昌, 吉岡英将, 吉村篤利, 金子高士, 原 宜興
    • Organizer
      日本歯科保存学会2013年度秋季学術大会
    • Place of Presentation
      秋田県総合生活文化会館(秋田市)
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] 歯肉縁下プラークの Toll-like receptor (TLR)2 および TLR4 活性化能と歯周組織の状態との関連性について2013

    • Author(s)
      佐藤佳昌、吉岡英将、吉村篤利、金子高士、原宜興
    • Organizer
      第139回日本歯科保存学会秋季学術大会
    • Place of Presentation
      秋田県総合生活文化会館(秋田市)
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] ROCK inhibitor Y-27632 maintains the proliferation of confluent human mesenchymal stem cells.2013

    • Author(s)
      Nakamura K, Yoshimura A, Kaneko T, Sato K, Shiraishi C, Yoshinaga M, Nakamura H, Hara Y
    • Organizer
      10th Asian Pacific Society of Periodontology Meeting
    • Place of Presentation
      Nara Prefectural New Public Hall(Nara,Japan)
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] TNF-α刺激により破骨細胞形成が促進されるRANKL前刺激条件の検討2013

    • Author(s)
      山下恭德, 鵜飼 孝, 吉村篤利, 金子高士, 白石千秋, 吉永美穂, 吉永泰周, 原 宜興
    • Organizer
      日本歯科保存学会2013年度秋季学術大会
    • Place of Presentation
      秋田県総合生活文化会館(秋田市)
    • Data Source
      KAKENHI-PROJECT-25463220
  • [Presentation] 18β-グリチルレチン酸は LPS 誘導性実験的歯周炎を抑制する2013

    • Author(s)
      藏本明子, 鵜飼孝, 中村弘隆, 吉永泰周, 髙森雄三, 野口惠司, 泉聡史, 白石千秋, 小野山美穂, 吉村篤利, 原宜興
    • Organizer
      第139回日本歯科保存学会秋季学術大会
    • Place of Presentation
      秋田県総合生活文化会館(秋田市)
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] TNF-α刺激により破骨細胞形成が促進されるRANKL前刺激条件の検討2013

    • Author(s)
      山下恭德, 鵜飼 孝, 吉村篤利, 金子高士, 白石千秋, 吉永美穂, 吉永泰周, 原 宜興
    • Organizer
      日本歯科保存学会2013年度秋季学術大会
    • Place of Presentation
      秋田県総合生活文化会館(秋田市)
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] ラットにおけるグラム陽性細菌の感作および歯肉溝内滴下は歯周組織破壊を促進する2013

    • Author(s)
      長野史子、金子高士、吉永泰周、鵜飼孝、藏本明子、中津晋、高森雄三、野口恵司、原 宜興
    • Organizer
      第4回口腔環境制御研究カテゴリー集会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-24593127
  • [Presentation] TNFα刺激により破骨細胞形成が促進される RANKL 前刺激条件の検討2013

    • Author(s)
      山下恭德, 鵜飼 孝, 吉村篤利, 金子高士, 白石千秋, 吉永美穂, 吉永泰周, 原 宜興
    • Organizer
      第139回日本歯科保存学会秋季学術大会
    • Place of Presentation
      秋田県総合生活文化会館(秋田市)
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] TNFα刺激により破骨細胞形成が促進されるRANKL前刺激条件の検討2013

    • Author(s)
      山下 恭德、鵜飼 孝、原 宜興
    • Organizer
      平成25年度日本歯周病学会九州五大学・日本臨床歯周病学会九州支部合同研修会
    • Place of Presentation
      九州歯科大学(北九州市)
    • Data Source
      KAKENHI-PROJECT-25463220
  • [Presentation] ペプチドグリカンで感作したマウスのT細胞はLPS存在下で破骨細胞形成を促進する2012

    • Author(s)
      横山美穂, 鵜飼 孝,山下恭徳,吉永泰周,中村弘隆,尾崎幸生,金子高士,吉村篤利,原 宜興
    • Organizer
      第55回秋季日本歯周病学会学術大会
    • Place of Presentation
      つくば市
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Analysis of the pro-inflammatory property of subgingival plaque.2012

    • Author(s)
      Sato K, Yoshioka H, Yoshimura A, Kaneko T, Hara Y.
    • Organizer
      Firirst International Conference on Porphyromonas gingivalis and Related Bacterial Species.
    • Place of Presentation
      Nagasaki, Japan
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] A single nucleotide polymorphism rs11536889 in 3’-untranslated region of TLR4 contributes to the regulation of Toll-like receptor 4 expression.2012

    • Author(s)
      Yoshimura A, Sato K, Kaneko T, Li X, Matsumura H, Ogata Y, Hara Y.
    • Organizer
      The 12th Biennial International Endotoxin and Innate Immunity Society Meeting
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] Topical application of sonicated and heat-treated Staphylococcus aureus or Aggregatibacter actinomycetemcomitans 
into rat gingival sulcus induces periodontal tissue destruction after immunization.2012

    • Author(s)
      Nagano F, Yoshinaga Y, Kaneko T, Kuramoto A , Nakatsu S , Kishimoto T, Takamori Y, Noguchi S, Hara Y
    • Organizer
      7th Conference of the European Federation of Periodontology
    • Place of Presentation
      Wien, Austria
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] ペプチドグリカンで感作したマウスのT 細胞はLPS存在下で破骨細胞形成を促進する2012

    • Author(s)
      横山美穂, 鵜飼孝, 山下恭徳,吉永泰周,中村弘隆,尾崎幸生,金子高士,吉村篤利,原宜興
    • Organizer
      第55回秋季日本歯周病学会学術大会
    • Place of Presentation
      筑波、茨城
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] 菌体破砕物による感作とその歯肉溝内滴下は歯周ポケットの形成を誘導する2012

    • Author(s)
      長野史子、吉永泰周、金子高士、藏本明子、中津晋、高森雄三、野口恵司、岸本隆明、原 宜興
    • Organizer
      第54回春季日本歯周病学会学術大会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24593127
  • [Presentation] A single nucleotide polymorphism rs11536889 in 3’-untranslated region of TLR4 contributes to the regulation of Toll-like receptor 4 expression2012

    • Author(s)
      Atsutoshi Yoshimura, Kayo Sato, Takashi Kaneko, Xinyue Li, Hiroyoshi Matsumura, Yorimasa Ogata, Yoshitaka Hara
    • Organizer
      The 12th Biennial International Endotoxin and Innate Immunity Society Meeting
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] 菌体破砕物による感作とその歯肉溝内滴下は歯周ポケットの形成を誘導する.2012

    • Author(s)
      長野史子、吉永泰周、金子高士、蔵本明子、中津 晋、髙森雄三、野口恵司、岸本隆明、原 宜興
    • Organizer
      第54回春季日本歯周病学会学術大会
    • Place of Presentation
      札幌、北海道
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] Analysis of the pro-inflammatory property of subgingival plaque2012

    • Author(s)
      Kayo Sato, Hidenobu Yoshioka, Atsutoshi Yoshimura, Takashi Kaneko, Yoshitaka Hara
    • Organizer
      First International Conference on Porphyromonas gingivalis and Related Bacterial Species
    • Place of Presentation
      Nagasaki, Japan
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Effects of rs11536889 G/C polymorphism on Toll-like receptor 4 expression2012

    • Author(s)
      Kayo Sato, Atsutoshi Yoshimura, Takashi Kaneko, Takaaki Kishimoto, Hiroyoshi Matsumura, Xinyue Li, Yorimasa Ogata, Yoshitaka Hara
    • Organizer
      The 98th Annual Meeting of American Academy of Periodontology in collaboration with the Japanese Society of Periodontology
    • Place of Presentation
      Los Angeles, USA
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Peptidoglycan and lipopolysaccharide synergistically enhance bone resorption and osteoclastogenesis2012

    • Author(s)
      Takashi Kaneko, Takaaki Kishimoto, Takashi Ukai, Miho Yokoyama, Yasunori Yoshimaga, Kayo Sato, Atsutoshi Yoshimura, Yoshitaka Hara
    • Organizer
      The 98th Annual Meeting of American Academy of Periodontology in collaboration with the Japanese Society of Periodontology
    • Place of Presentation
      Los Angeles, USA
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] T cell from mice immunized with peptidoglycan accerelates lipopolisacchride-induced osteoclastgnesis2012

    • Author(s)
      Yokoyama M, Ukai T, Kaneko T, Kishimoto T, Sato K, Shiraishi C, Ozaki Y, Yoshimura A, Hara Y
    • Organizer
      7th Congress of the European Federation of Periodontology
    • Place of Presentation
      Vienna, Austria
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] The crystals in dental calculus accelerate IL-1β production through activation of NLRP3 inflammasome in mouse macrophage and human peripheral polymorphonuclear leukocyte2012

    • Author(s)
      Nakamura H, Yoshimura A, Kaneko T, Latz E, HaraY
    • Organizer
      The 12th Biennial International Endotoxin and Innate Immunity Society Meeting
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] T cells from mice immunized with peptidoglycan accelerates lipopolysaccharide-induced osteoclastogenesis2012

    • Author(s)
      Yokoyama M, Ukai T, Kaneko T, Kishimoto T, Sato K, Shiraishi C, Ozaki Y, Yoshimura A, Hara Y
    • Organizer
      7th Conference of the European Federation of Periodontology
    • Place of Presentation
      Wien, Austria
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] LPSの全身的な感作後のLPS歯肉溝内投与はアタッチメントロスを誘導する。2012

    • Author(s)
      吉永泰周, 中津 晋, 藏本明子, 鵜飼 孝, 金子高士, 市村育久, 押野一志, 矢納義高, 原 宜興
    • Organizer
      第136回日本歯科保存学会春季学術大会
    • Place of Presentation
      宜野湾、沖縄
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] Toll-Like Receptor 4発現におけるTLR4遺伝子3’側非翻訳領域の一塩基多型rs11536889の役割2012

    • Author(s)
      佐藤佳昌, 吉村篤利, 金子高士, 岸本隆明, 松村浩禎, 小方頼昌, 原 宜興
    • Organizer
      第136回日本歯科保存学会秋季学術大会
    • Place of Presentation
      宜野湾市
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] Peptidoglycan and lipopolysaccharide synergistically enhance bone resorption and osteoclastogenesis.2012

    • Author(s)
      Kaneko T, Kishimoto T, Ukai T, Yokoyama M, Yoshimaga Y, Sato K, Yoshimura A, Hara T
    • Organizer
      The 98th Annual Meeting American Academy of Periodontology in collaboration with the Japanese Society of Periodontology
    • Place of Presentation
      Los Angeles, CA
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] 歯石中のリン酸カルシウム結晶はNLRP3インフラマソームを活性化する2012

    • Author(s)
      中村弘隆, 吉村篤利. 金子高士, Eicke Latz, 原 宜興
    • Organizer
      2012年度日本臨床歯周病学会九州支部・日本歯周病学会九州5大学合同研修会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] The crystals in dental calculus accelerate IL-1β production through activation of NLRP3 inflammasome in mouse macrophage and human peripheral polymorphonuclear leukocyte2012

    • Author(s)
      Nakanura H, Yoshimura A, Kaneko T, Latz E, Hara H.
    • Organizer
      The 12th Biennial International Endotoxin and Inn.ate Immunity Society Meeting
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] Effects of rs11536889 G/C polymorphism on Toll-like receptor 4 expression.2012

    • Author(s)
      Sato K, Yoshimura A, Kaneko T, Kishimoto T, Matumura H, Li X, Ogata Y, Hara Y
    • Organizer
      The 98th Annual Meeting of American Academy of Periodontology in collaboration with the Japanese Society of Periodontology
    • Place of Presentation
      Los Angeles, CA
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] Toll-Like Receptor 4発現におけるTLR4遺伝子3’側非翻訳領域の一塩基多型rs11536889の役割2012

    • Author(s)
      佐藤佳昌,吉村篤利,金子高士,岸本隆明,松村浩禎,小方頼昌,原宜興
    • Organizer
      第136回日本歯科保存学会春季学術大会
    • Place of Presentation
      宜野湾、沖縄
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] Topical application of sonicated and heat-treated Staphyrococcus aureus or Aggregatebacter actinomycetemcomitans into rat gingival sulcus induces periodontal tissue destruction after immunization.2012

    • Author(s)
      Fumiko Nagano, Yasunori Yoshinaga, Takashi Kaneko, Akiko Kuramoto, Susumu Nakatsu, Takaaki Kishimoto, Yuzo Takamori, Satosi Noguchi, Yoshitaka Hara
    • Organizer
      7th Conference of the Eyropean Federation of Periodontology
    • Place of Presentation
      Vienna
    • Data Source
      KAKENHI-PROJECT-24593127
  • [Presentation] 骨吸収に対するペプチドグリカンとリポ多糖の協調作用に関する研究2011

    • Author(s)
      岸本隆明、金子高士、鵜飼孝、横山美穂、吉永泰周、佐藤佳昌、長野史子、山下泰徳、吉村篤利、原宜興
    • Organizer
      日本歯科保存学会、プログラムおよび講演抄録集、2011年度秋季学術大会
    • Place of Presentation
      大阪国際交流センター
    • Data Source
      KAKENHI-PROJECT-21592627
  • [Presentation] ペプチドグリカンはリポ多糖と協調して歯槽骨吸収と破骨細胞形成を促進する2011

    • Author(s)
      岸本隆明、金子高士、鵜飼孝、横山美穂、長野史子、佐藤佳昌、吉永泰周、吉村篤利、原宜興
    • Organizer
      第54回春季日本歯周病学会学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2011-05-27
    • Data Source
      KAKENHI-PROJECT-21592627
  • [Presentation] Locally administered interferon-gamma accelerates RANKL-induced osteoclastogenesis in the presence of lipopolysaccharide2010

    • Author(s)
      E. R. Ayon Haro, T. Ukai, M. Yokoyama, T. Kishimoto, Y. Yoshinaga, Y. Hara
    • Organizer
      The 96^<th> annual meeting of the American Academy of Periodontology
    • Place of Presentation
      Honolulu, Hawaii
    • Data Source
      KAKENHI-PROJECT-21592627
  • [Presentation] ラット歯肉溝へのLPSおよび抗LPS IgGの交互滴下によりアタッチメントロスが誘導される2010

    • Author(s)
      藏本明子, 金子高士, 吉永泰周, 鵜飼孝, 白石千秋, 岸本真実, 横山美穂, 岸本隆明, 市村育久, 押野一志, 原宜興
    • Organizer
      第53回春季日本歯周病学会学術大会、盛岡市民文化ホールおよびいわて県民情報交流センター(アイーナ)
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] LPS注入マウス脾細胞によるfoam cell形成の促進2010

    • Author(s)
      鵜飼孝、岸本隆明、横山美穂、原宜興
    • Organizer
      第53回秋季日本歯周病学会学術大会
    • Place of Presentation
      高松
    • Year and Date
      2010-09-19
    • Data Source
      KAKENHI-PROJECT-21592627
  • [Presentation] 「幹細胞シートの作製に関する研究」2010

    • Author(s)
      中村康平、安部達也、原宜興
    • Organizer
      第53回秋季日本歯周病学会学術大会
    • Place of Presentation
      高松
    • Data Source
      KAKENHI-PROJECT-22592315
  • [Presentation] 幹細胞シートの作製2010

    • Author(s)
      中村康平、安部達也、原宜興
    • Organizer
      日本歯周病学会九州5大学・日本臨床歯周病学会九州支部合同研修会
    • Place of Presentation
      福岡県歯科医師会館(福岡市)
    • Year and Date
      2010-11-23
    • Data Source
      KAKENHI-PROJECT-22592315
  • [Presentation] CD40L accelerates osteoclastogenesis induced by RANKL and LPS2010

    • Author(s)
      Yokoyama M, Ukai T, Kishimoto T, Ayon Haro ER, Kuramoto A, Yoshinaga Y, Takamori Y, Hara Y
    • Organizer
      88^<th> General Session & Exhibition of the IADR
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21592627
  • [Presentation] 幹細胞シートの作製に関する研究2010

    • Author(s)
      中村康平、安部達也、原宜興
    • Organizer
      第53回秋季日本歯周病学会学術大会
    • Place of Presentation
      かがわ国際会議場(高松市)
    • Year and Date
      2010-09-19
    • Data Source
      KAKENHI-PROJECT-22592315
  • [Presentation] 「幹細胞シートの作製」2010

    • Author(s)
      中村康平、安部達也、原宜興
    • Organizer
      2010年度日本臨床歯周病学会九州支部・日本歯周病学会九州5大学合同研修会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22592315
  • [Presentation] LPS存在下でCD40Lはin vivoにおける破骨細胞形成を促進する2010

    • Author(s)
      横山美穂、鵜飼孝、Ayon Haro Esperanza Raquel、岸本隆明、藏本明子、白石千秋、吉永美穂、原宜興
    • Organizer
      第53回秋季日本歯周病学会学術大会
    • Place of Presentation
      高松
    • Year and Date
      2010-09-19
    • Data Source
      KAKENHI-PROJECT-21592627
  • [Presentation] Cyclosporin A and phenytoin differently modulate Toll-Like receptor-mediated responses in human gingival fibroblasts.2009

    • Author(s)
      Suzuki AMM, Yoshimura A, Kaneko T, Hara Y
    • Organizer
      The 9^<th> World Congress on Inflammation.
    • Place of Presentation
      Keio plaza hotel, Tokyo.
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] NODによる歯周病原細菌の認識2009

    • Author(s)
      金子高士、吉村篤利、原宜興
    • Organizer
      第131回日本歯科保存学会2009年度秋季学術大会
    • Place of Presentation
      仙台市仙台国際センター
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] 歯肉炎上プラークのTLR4刺激作用と末梢血単核球からのサイトカイン産生誘導能との関連2009

    • Author(s)
      吉村篤利、山口竜亮、吉岡英将、佐藤佳昌、金子高士、原宜興
    • Organizer
      第52回春季日本歯周病学会学術大会
    • Place of Presentation
      岡山市岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] 歯肉縁下プラークのToll-1ike receptor (TLR) 2およびTLR4刺激作用と歯周病臨床パラメーターの関連性について2008

    • Author(s)
      吉村篤利, 吉岡英将, 山口竜亮, 金子高士, 原宜興
    • Organizer
      第129回日本歯科保存学会2008年度秋季学術大会
    • Place of Presentation
      富山市富山国際会議場
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] Analysis of the activity to induce TLR2- and TLR4-mediated stimulation of supragingival and subgingival plaque.2008

    • Author(s)
      Yoshimura A, Yoshioka H, Suzuki AMM, Kishimoto M, Kaneko T, Golenbock DT, Hara Y.
    • Organizer
      10^<th> Biannual IEIIS Meeting, International Endotoxin and Innate Immunity Society Edinburgh
    • Place of Presentation
      UK
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] Locally administrated T cells from LPS-immunized mice accelerate LPS-induced bone resorption2008

    • Author(s)
      Hara Y, Ozaki Y, Yokoyama M, Shiraishi C, Yoshinaga Y, Ukai T
    • Organizer
      The 10th International Endotoxin and Innate Immunity Society meeting
    • Place of Presentation
      Edinburgh, UK
    • Data Source
      KAKENHI-PROJECT-19592389
  • [Presentation] Cyclosporin A modulates TLR-mediated responses in human gingival fibroblasts.2008

    • Author(s)
      Suzuki AMM, Yoshimura A, Kaneko T, Kishimoto M, Hara Y.
    • Organizer
      10^<th> Biannual IEIIS Meeting, International Endotoxin and Innate Immunity Society Edinburgh
    • Place of Presentation
      UK
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] Locally administated T cells fromLPS-induced bone resorption2008

    • Author(s)
      Hara Y
    • Organizer
      The 10th IEIIS meeting
    • Place of Presentation
      Edinburgh, UK
    • Year and Date
      2008-07-31
    • Data Source
      KAKENHI-PROJECT-19592389
  • [Presentation] Effects of Cyclosporin A on TLR-Mediated Responses of Gingival Fibroblasts.2008

    • Author(s)
      Suzuki AMM, Yoshimura A, Kaneko T, Hara Y.
    • Organizer
      第51回春季日本歯周病学会総会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] 歯周病原性細菌のNOD活性化能に関する研究2008

    • Author(s)
      奥川剛志、金子高士、吉村篤利、原宜興
    • Organizer
      第51回春季日本歯周病学会春季学術大会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] Identification of a cell surface component of Porphyromonas gingivalis that induces TLR2- and TLR4-independent activation of NF-kB in CHO cells.2008

    • Author(s)
      Kishimoto M, Yoshimura A, Naito M, Haruyama K, Kaneko T, Nakayama K, Hara Y.
    • Organizer
      10^<th> Biannual IEIIS Meeting, International Endotoxin and Innate Immunity Society Edinburgh
    • Place of Presentation
      UK
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] NOD mediates cytoplasmic sensing of periodontal pathogens.2008

    • Author(s)
      Kaneko T, Okugawa T, Yoshinaga M, Kishimoto M, Yoshimura A, Hara Y.
    • Organizer
      10^<th> Biannual IEIIS Meeting, International Endotoxin and Innate Immunity Society Edinburgh
    • Place of Presentation
      UK
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] Periodontal tissue engineering by transplantation of multilayered gingival fibroblasts2007

    • Author(s)
      Kahori, Nakajima, Tatsuya, Abe, Maya, Tanaka, Yoshitaka, Hara
    • Organizer
      11th International Academy of Periodontology(IAP) Congress
    • Place of Presentation
      Berne, Swiss
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592265
  • [Presentation] T cells are closely related to LPS-induced bone resorption.2007

    • Author(s)
      Y Hara, et. al.
    • Organizer
      International Academy of Periodontology
    • Place of Presentation
      Bern, Switzerland
    • Data Source
      KAKENHI-PROJECT-19592389
  • [Presentation] T cells are closely related to LPS-induced bone resorption. The 11th^<th> International Biennial Congress of International Academy of Periodontology2007

    • Author(s)
      Hara Y, Yamaguchi M, Ukai T, Onoyama M, Yokoyama M, Ozaki Y, Kaneko T
    • Organizer
      Bern, Switzerland
    • Data Source
      KAKENHI-PROJECT-19592389
  • [Presentation] Periodontal tissue engineering by transplantation of multilayered gingival fibroblasts2007

    • Author(s)
      Kahori Nakajima, Tatsuya Abe, Maya Torisu, Yoshitaka Hara.
    • Organizer
      11th International Academy of Periodontology(IAP)Congress
    • Place of Presentation
      スイス、ベルン
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592265
  • [Presentation] Transplantation od alkaline phosphatase-expressing gingival fibroblasts into a rat periodontal defect.2006

    • Author(s)
      Kahori, Nakajima, Tatsuya, Abe, Maya, Tanaka, Yoshitaka, Hara
    • Organizer
      Japanese Society of Conservative Dentistry
    • Place of Presentation
      Kagoshima, Japan
    • Year and Date
      2006-11-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592265
  • [Presentation] アルカリホスファターゼを発現する線維芽細胞シートのラット歯周組織欠損部への移植2006

    • Author(s)
      中嶋 香、安部 達也、田中 麻弥、原 宜興
    • Organizer
      日本歯科保存学会2006年度秋季学術大会(第125回)
    • Place of Presentation
      鹿児島
    • Year and Date
      2006-11-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592265
  • [Presentation] Immune complex formed in rat gingival sulcus induces attachment loss.

    • Author(s)
      Kuramot A, Yoshinaga Y, Ukai T, Kaneko T, Shiraishi C, Yokoyama M, Sato T, Nagano F, Takamori Y, Hara Y.
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] RANKL priming accelerates osteoclast formation with resorptive activity in TNF-alpha-stimulated murine bone marrow macrophages independent of RANKL

    • Author(s)
      Yamashita Y, Ukai T, Takamori Y, Noguchi S, Montenegro Raudales JL, Nakamura H, Ozaki Y, Shiraishi C, Yoshimura A, Hara Y
    • Organizer
      100th Anniversary meeting of American Academy of Periodontology
    • Place of Presentation
      モスコンセンター (サンフランシスコ)
    • Year and Date
      2014-09-19 – 2014-09-22
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] TLR2およびTLR4リガンド投与マウス歯肉における炎症性および抗炎症性サイトカインの発現

    • Author(s)
      尾崎幸生、吉村篤利、金子高士、鵜飼孝、吉永泰周、Jorge Montenegro, Ziauddin SM、白石千秋、中村弘隆、藏本明子、原宜興
    • Organizer
      日本歯科保存学会2014年秋季学術大会
    • Place of Presentation
      山形テルサ(山形県・山形市)
    • Year and Date
      2014-10-30 – 2014-10-31
    • Data Source
      KAKENHI-PROJECT-23593066
  • [Presentation] NOD1 and NOD2 mediate cytoplasmic sensing of periodontal pathogens.

    • Author(s)
      Kaneko T, Okugawa T, Yoshimura A, Sato K, Hara Y.
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] RANKL priming accelerates osteoclast formation with resorptive activity in TNF-alpha-stimulated murine bone marrow macrophages independent of RANKL

    • Author(s)
      Yamashita Y, Ukai T, Takamori Y, Noguchi S, Montenegro Raudales JL, Nakamura H, Ozaki Y, Shiraishi C, Yoshimura A, Hara Y
    • Organizer
      100th American Academy of Periodontology
    • Place of Presentation
      San Francisco convention center (USA)
    • Year and Date
      2014-09-19 – 2014-09-24
    • Data Source
      KAKENHI-PROJECT-25463220
  • [Presentation] TLR2およびTLR4リガンド投与マウス歯肉における炎症性および抗炎症性サイトカインの発現

    • Author(s)
      尾崎幸生, 吉村篤利, 金子高士, 鵜飼 孝, 吉永泰周, Jorge Montenegro, Ziauddin SM, 白石千秋, 中村弘隆, 藏本明子, 原 宜興
    • Organizer
      日本歯科保存学会2014年度秋季学術大会
    • Place of Presentation
      山形テルサ(山形市)
    • Year and Date
      2014-10-30 – 2014-10-31
    • Data Source
      KAKENHI-PROJECT-24593126
  • [Presentation] An experimental model of periodontitis in LPS-Immunized rat.

    • Author(s)
      Yoshinaga Y, Kuramoto A, Kaneko T, Ukai T, Shiraishi C, Yoshinaga M, Sato T, Nagano F, Hara Y.
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] Cyclosporin A and phenytoin modulate inflammatory responses in gingival fibroblasts.

    • Author(s)
      Yoshimura A, Suzuki AMM, Y. Ozaki Y, Sato K, Kaneko T, Hara Y.
    • Data Source
      KAKENHI-PROJECT-20592432
  • [Presentation] LPS 感作と歯肉溝滴下による長い上皮性付着破壊に関する実験病理組織学的検討

    • Author(s)
      野口惠司、吉村篤利、鵜飼孝、白石千秋、吉永美穂、吉永泰周、藏本明子、高森雄三、泉聡史、原宜興
    • Organizer
      日本歯科保存学会2014年度春季学術大会
    • Place of Presentation
      滋賀県立芸術劇場(大津市)
    • Year and Date
      2014-06-19 – 2014-06-20
    • Data Source
      KAKENHI-PROJECT-24593126
  • 1.  YOSHIMURA Atsutoshi (70253680)
    # of Collaborated Projects: 16 results
    # of Collaborated Products: 115 results
  • 2.  UKAI Takashi (20295091)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 27 results
  • 3.  KANEKO Takashi (10284697)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 94 results
  • 4.  KATO Ihachi (30005087)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 5.  AONO Masao (70037498)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 6.  MAEDA Katsumasa (00117243)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 7.  TANI Masahiko (70188374)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 8.  ABE Yoshiriro (70202687)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 9.  松井 昌
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 10.  FUJITA S. (00181355)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 11.  廣藤 卓雄 (10189897)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 12.  IKEDA Yasuo (90274670)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 13.  ABE Tatsuya (80271112)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 14.  赤峰 昭文 (00117053)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 15.  TAKAHASHI H (20124597)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  NAKAYAMA Koji (80150473)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 17.  ICHIMARU Eiji (60223111)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  TANI Yoshiko (90196436)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 19.  渋谷 武宏
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  YOSHINAGA Yasunori (60452869)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 21.  YAMAGUCHI Akira (00142430)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 22.  OZAKI Yukio (60204187)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  柴田 恭明 (80253673)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  鎮守 信弘 (90163758)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  KANEKO Satoshi (00342907)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  FUJII Yoshito (10404237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  TSUKUBA Tomoko (70336080)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  KUNIMATSU Kazushi (20170011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  NISHIDA Eiji (90336173)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  KATSUBE Ken-ichi (20233760)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  SAKAMOTO Kei (00302886)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  TAMAMURA Sadahiro (70431963)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  SHIRAISHI Chiaki (30336177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  NAITO Mariko (20244072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  MIYATAKE Sachiko (40190798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  HAMACHI Takafumi (80198811)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  山木 昌雄 (00034166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  加藤 有三 (20014128)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  作花 済夫 (10027021)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  長田 豊 (90160837)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  塚崎 智雄 (50315230)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  進藤 裕幸 (30107677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  相田 宜利 (10127954)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  古川 猛士 (30128087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  宮崎 敏博 (10174161)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi