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SASAKI Hiroyuki  佐々木 博之

Researcher Number 60170693
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-5358-5853
Affiliation (based on the past Project Information) *help 2015: 帝京平成大学, 健康医療スポーツ学部, 教授
2007 – 2012: 東京慈恵会医科大学, 医学部, 准教授
2004 – 2006: 東京慈恵会医科大学, 医学部, 助教授
2004: 東京慈恵会医科大学, DNA研究所, 講師
Review Section/Research Field
Principal Investigator
General anatomy (including Histology/Embryology)
Except Principal Investigator
Biological Sciences / Morphological basic dentistry / Neurophysiology and muscle physiology / Complex systems / Neurophysiology and muscle physiology
Keywords
Principal Investigator
Tet-Off / GFP / Claudin / Tight junction / ZO-1 / クローディン / タイトジャンクション
Except Principal Investigator
タイトジャンクション / アドヘレンスジャンクション / claudin … More / tight junction / 細胞間接着 / クローディン / 細胞接着 / 上皮細胞 / occludin / オクルディン / ノックアウトマウス / 細胞内Ca / 拡張型心筋症 / Ca感受性 / 細胞内Ca^<2+> / トロポニン / Ca^<2+>感受性 / メルリン / ERM蛋白質 / がん / マーリン / ERM / ZO-1 / tooth / amelogenesis / amelohlast / 免疫組織化学 / 細胞間輸送 / 細胞接着装置 / エナメル質 / 歯 / エナメル質形成 / エナメル芽細胞 / cell proliferation / knockout mouse / epidermal barrier / ERM proteins / cell-cell adhesion / カドヘリン / β-カテニン / α-カテニン / ラディキシン / 大腸癌 / PDZドメイン / MUPP1 / 血液脳関門 / ノックアウト / ドラッグデリバリー / GFP / 転移浸潤 / 上皮間葉転換 / ZO-2 / Snail / 細胞増殖 / 上皮間バリアー / RAA系 / 線維化 / アンギオテンシン / 計算生理学 / フィジオーム / 細胞微細構造 / 数理生物学 / 不整脈 / 心臓 / 電気生理学 / プラットフォーム / 生体機能シミュレーション / バリア / クローディ / 細胞間接着装 / プロテオミクス / バリアー / 細胞間バリアー / 細胞骨格 / 細胞膜 / プロテオーム / 生体分子 / 細胞・組織 / 繊毛 / Odf2 / 炎症 / アピカル膜 / タイトジャンクション(TJ) / 肝臓毛細胆管画分 / CaMKII / 細胞内Ca2^<2+> / Ca 感受性 / 心エコー / レニン・アンギオテンシン系 / Ca transient / マウス / DCM / アンギオテンシンII / Caトランジェント / 筋小胞体 / Ca^<2+> / アンギオテンシンII受容体 / トロポニンT / 心筋 / タイトジャンクシ / Gene Chip / 膜インタフェイス / トリセルリン / アドへレンスジャンクション / ユビキチン化 / 近位尿細管 / 腸管バリア / 血管内皮細胞 Less
  • Research Projects

    (9 results)
  • Research Products

    (73 results)
  • Co-Researchers

    (29 People)
  •  Research and development of a software platform for integrative multi-level systems biology

    • Principal Investigator
      Kurachi Yoshihisa
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Osaka University
  •  Molecular mechanisms of an improvement in prognosis in the mouse model of dilated cardiomyopathy treated by inhibition of the RAA system

    • Principal Investigator
      KURIHARA Satoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Jikei University School of Medicine
  •  上皮細胞における膜インターフェイスとしての細胞間接着関連分子群

    • Principal Investigator
      月田 早智子
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Molecular mechanism of contractile dysfunction and the alteration of intracellular Ca^<2+> handling caused by mutation of cardiac troponin T

    • Principal Investigator
      KURIHARA Satoshi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Jikei University School of Medicine
  •  A novel approach to cell adhesion/cytoskeleton research for exploring the epithelia cell system

    • Principal Investigator
      TSUKITA Sachiko
    • Project Period (FY)
      2007 – 2012
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Osaka University
  •  Molecular mechanisms of cell-cell adhesion in cancer cells

    • Principal Investigator
      FURUSE Mikio
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
      Kyoto University
  •  Expression patterns of tight junction associated proteins, occludin and claudins in ameloblasts during amelogenesis of mouse incisor.

    • Principal Investigator
      YAMAMOTO Toshio
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Okayama University
  •  Dynamic analysis of tight junction strandsPrincipal Investigator

    • Principal Investigator
      SASAKI Hiroyuki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      The Jikei University School of Medicine
  •  Molecular mechanism for cell-cell adhesion in canceration and metastasis

    • Principal Investigator
      TSUKITA Shoichiro
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      KYOTO UNIVERSITY

All 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining.2012

    • Author(s)
      Palmela I, Sasaki H, Cardoso FL, Moutinho M, Kim KS, Brites D, Brito MA.
    • Journal Title

      Frontiers in cellular neuroscience

      Volume: 6(22)

    • DOI

      10.3389/fncel.2012.00022

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] Structural changes in isometrically contracting insect flight muscle trapped following a mechanical perturbation.2012

    • Author(s)
      Wu S, Liu J, Reedy MC, Perz-Edwards RJ, Tregear RT, Winkler H, Franzini-Armstrong C, Sasaki H, Lucaveche C, Goldman YE, Reedy MK, Taylor KA.
    • Journal Title

      PLoS One

      Volume: 7(6) Issue: 6 Pages: e39422-e39422

    • DOI

      10.1371/journal.pone.0039422

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] Tight junction regulates epidermal calcium ion gradient and differentiation.2011

    • Author(s)
      M Kurasawa, T Maeda, A Oba, T Yamamoto, H Sasaki
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] Neuronal expression, cytosolic localization, and developmental regulation of the organic solute carrier partner 1 in the mouse brain2011

    • Author(s)
      K Hiratsuka, A Momose, N Takagi, H Sasaki, S-A Yin, M Fujita, T Ohtomo, K Tanonaka, H Toyoda, H Suzuki, T Kurosawa, J Yamada
    • Journal Title

      Histochemistry and Cell Biology

      Volume: 135 Pages: 229-238

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] A look at tricellulin, a recently discovered tight junction protein2011

    • Author(s)
      C Mariano, H Sasaki, D Brites, MA Brito
    • Journal Title

      European Journal of Cell Biology

      Volume: 90(10) Issue: 10 Pages: 787-796

    • DOI

      10.1016/j.ejcb.2011.06.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] LSR defines cell corners for tricellular tight junction formation in epithelial cells.2011

    • Author(s)
      S Masuda, Y Oda, H Sasaki, J Ikenouchi, T Higashi, M Akashi, E Nishi, M Furuse.
    • Journal Title

      Journal of Cell Science

      Volume: 124(Pt 4) Pages: 548-555

    • NAID

      40019439596

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] Tight junction regulates epidermal calcium ion gradient and differentiation2011

    • Author(s)
      M Kurasawa, T Maeda, A Oba, T Yamamoto, H Sasaki
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 406(4) Issue: 4 Pages: 506-511

    • DOI

      10.1016/j.bbrc.2011.02.057

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] Claudin-2-deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules.2010

    • Author(s)
      S Muto, M Hata, J Taniguchi, S Tsuruoka, K Moriwaki, M Saitou, K Furuse, H Sasaki, A Fujimura, M Imai, E Kusano, S Tsukita, M Furuse.
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 107(17) Pages: 8011-8016

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] Claudin-2-deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules.2010

    • Author(s)
      Muto S, Hata M, Taniguchi J, Tsuruoka S, Moriwaki K, Saitou M, Furuse K, Sasaki H, Fujimura A, Imai M, Kusano E, Tsukita S, Furuse M.
    • Journal Title

      Proc Natl Acad Sci U S A 107

      Pages: 8011-8016

    • Data Source
      KAKENHI-PROJECT-17014044
  • [Journal Article] Tight junction-associated MARVEL proteins marvelD3, tricellulin, and occludin have Ddistinct but overlapping functions.2010

    • Author(s)
      D.R Raleigh, A.M Marchiando, Y Zhang, L Shen, H Sasaki, Y Wang, M.Long, J.R.Turner
    • Journal Title

      Molecular Biology of the Cell

      Volume: 21(7) Pages: 1200-1213

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] Electron tomography of cryofixed, isometrically contracting insect flight muscle reveals novel actin-myosin interactions.2010

    • Author(s)
      S Wu, J Liu, M.C Reedy, R.T Tregear, H Winkler, C Franzini-Armstrong, H Sasaki, C Lucaveche, Y.E.Goldman, M.K Reedy, K.A Taylor
    • Journal Title

      PLoS One

      Volume: 5(9)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] Transdermal delivery of a readthrough-inducing drug : a new approach of gentamicin administration for the treatment of nonsense mutation-me diated disorders.2010

    • Author(s)
      M Shiozuka, A Wagatsuma, T Kawamoto, H Sasaki, K Shimada, Y Takahashi, Y Nonomura, R Matsuda
    • Journal Title

      The Journal of Biochemistry

      Volume: 147(4) Pages: 463-470

    • NAID

      10027874843

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Journal Article] The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells2009

    • Author(s)
      Takahashi S, Iwamoto N, Sasaki H, Ohashi M, Oda Y, Tsukita S, Furuse M.
    • Journal Title

      J Cell Sci 122

      Pages: 985-994

    • Data Source
      KAKENHI-PROJECT-17014044
  • [Journal Article] Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca2+ leak in mouse heart2009

    • Author(s)
      Morimoto S, O-Uchi J, Kawai M, Hoshina T, Kusakari Y, Komukai K, Sasaki H, Hongo K, Kurihara S
    • Journal Title

      BBRC 390

      Pages: 87-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500357
  • [Journal Article] Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca^<2+> leak in mouse heart.2009

    • Author(s)
      Morimoto S, O-Uchi J, kawai M, Hoshina T, Kusakari Y, Komukai K, Sasaki H, Hongo K, Kurihara S
    • Journal Title

      BBRC 390

      Pages: 87-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500357
  • [Journal Article] Loss of occludin affects tricellular localization of tricellulin2008

    • Author(s)
      Ikenouchi J, Sasaki H, Tsukita S, Furuse M, Tsukita S
    • Journal Title

      Mol Biol Cell 19

      Pages: 4687-4693

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Journal Article] Megaintestine in claudin-15- deficient mice2008

    • Author(s)
      Tamura, A., Kitano, Y., Hata, M., Katsuno, T., Moriwaki, K., Sasaki, H., Hayashi, H., Suzuki, Y., Noda, T., Furuse, M., Tsukita, Sh., Tsukita, Sa.
    • Journal Title

      Gastroenterology 134

      Pages: 523-534

    • Data Source
      KAKENHI-PROJECT-19GS0313
  • [Journal Article] Loss of occludin affects tricellular localization of tricellulin.2008

    • Author(s)
      Ikenouchi J, Sasaki H, Tsukita S, Furuse M, Tsukita S.
    • Journal Title

      Mol Biol Cell 19

      Pages: 4687-4693

    • Data Source
      KAKENHI-PROJECT-17014044
  • [Journal Article] Megaintestine in claudin-15-deficient mice2008

    • Author(s)
      Tamura A, Kitano Y, Hata M, Katsuno T, Moriwaki K, Sasaki H, Hayashi H, Suzuki Y, Noda T, Furuse M, Tsukita S, Tsukita S.
    • Journal Title

      Gastroenterology 134

      Pages: 523-534

    • Data Source
      KAKENHI-PROJECT-17014044
  • [Journal Article] Interaction of alpha1-adrenoceptor subtypes with different G proteins induces opposite effects on cardiac L-type Ca2 channel2008

    • Author(s)
      O-Uchi J, Sasaki H, Morimoto S, Kusakari Y, Shinji H, Obata T, Hongo K, Komukai K, Kurihara S
    • Journal Title

      Circ Res 102(11)

      Pages: 1378-1388

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500357
  • [Journal Article] Interaction of alphal-adrenoceptor subtypes with different G proteins induces opposite effects on cardiac L-type Ca^<2+>channel.2008

    • Author(s)
      O-Uchi J, Sasaki H, Morimoto S, Kusakari Y, Shinji H, Obata T, Hongo K, Komukai K, Kurihara S
    • Journal Title

      Circ Res. 102(11)

      Pages: 1378-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500357
  • [Journal Article] ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation.2006

    • Author(s)
      Umeda K, Ikenouchi J, Katahira-Tayama S, Furuse K, Sasaki H, Nakayama M, Matsui T, Tsukita S, Furuse M, Tsukita S.
    • Journal Title

      Cell 126

      Pages: 741-754

    • Data Source
      KAKENHI-PROJECT-17014044
  • [Journal Article] Tight junctions in Schwann cells of peripheral myelinat-ed axons : a lesson from claudin-19-deficient mice.2005

    • Author(s)
      Miyamoto T., Morita K., Takemoto D., Sasaki H., et al.
    • Journal Title

      J. Cell Biol 169(3)

      Pages: 527-538

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Alpha1-adrenoceptor stimulation potentiates L-type Ca2+ current through Ca2+/calmodulin-dependent PK II (CaMKII) activation in rat ventricular myocytes.2005

    • Author(s)
      O-Uchi J., Kusakari Y., Sasaki H., et al.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 102(26)

      Pages: 9400-9405

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Tight junctions in Schwann cells of peripheral myelinated axons : a lesson from claudin-19-deficient mice.2005

    • Author(s)
      Miyamoto T., Morita K, Sasaki H., et al.
    • Journal Title

      J.Cell Biol. 169(3)

      Pages: 527-538

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Alpha1-adrenoceptor stimulation potentiates L-type Ca2+ current through Ca2+/calmodulin-dependent PK II (CaMKII) activation in rat ventricular myocytes.2005

    • Author(s)
      O-Uchi J., Komukai K., Kusakari Y., Obata T., Sasaki H., et al.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 102(26)

      Pages: 9400-9405

    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.2005

    • Author(s)
      Ikenouchi J., Furuse M., Furuse K., Sasaki H., Tsukita S., Tsukita S.
    • Journal Title

      J.Cell Biol. 171(6)

      Pages: 939-945

    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.2005

    • Author(s)
      Ikenouchi J, Furuse M, Furuse K, Sasaki H, Tsukita S, Tsukita S.
    • Journal Title

      J Cell Biol 171

      Pages: 939-945

    • Data Source
      KAKENHI-PROJECT-17014044
  • [Journal Article] Specificity and biomineralization activities of Ti-binding peptide-1 (TBP-1).2005

    • Author(s)
      Sano K., Sasaki H., Shiba K.
    • Journal Title

      Langmuir 21(7)

      Pages: 1717-1722

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Alphal-adrenoceptor stimulation potentiates L-type Ca2+ current through Ca2+/calmodulin-dependent PK II(CaMKII) activation in rat ventricular myocytes.2005

    • Author(s)
      O-Uchi J., Kusakari Y., Obata T., Sasaki H., et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 102(26)

      Pages: 9400-9405

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.2005

    • Author(s)
      Mimori-Kiyosue Y., Grigoriev I., Lansbergen G., Sasaki H., et al.
    • Journal Title

      J.Cell Sci. 168(1)

      Pages: 141-153

    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.2005

    • Author(s)
      Mimori-Kiyosue Y., Grigoriev I., Sasaki H., et al.
    • Journal Title

      J. Cell Sci. 168(1)

      Pages: 141-153

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice.2005

    • Author(s)
      Miyamoto T, Morita K, Takemoto D, Takeuchi K, Kitano Y, Miyakawa T, Nakayama K, Okamura Y, Sasaki H, Miyachi Y, Furuse M, Tsukita S.
    • Journal Title

      J Cell Biol 169

      Pages: 527-538

    • Data Source
      KAKENHI-PROJECT-17014044
  • [Journal Article] CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.2005

    • Author(s)
      Mimori-Kiyosue Y., Grigoriev I., Sasaki H., et al.
    • Journal Title

      J.Cell Sci. 168(1)

      Pages: 141-153

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.2005

    • Author(s)
      Ikenouchi J., Furuse M., Sasaki H., et al.
    • Journal Title

      J.Cell Biol. 171(6)

      Pages: 939-945

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Tight junctions in Schwann cells of peripheral myelinated axons : a lesson from claudin-19-deficient mice.2005

    • Author(s)
      Miyamoto T., Morita K., Takemoto D., Takeuchi K., Sasaki H., et al.
    • Journal Title

      J.Cell Biol. 169(3)

      Pages: 527-538

    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.2005

    • Author(s)
      Ikenouchi J., Furuse M., Furuse K., Sasaki H., et al.
    • Journal Title

      J. Cell Biol 171(6)

      Pages: 939-945

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Membrane-embedded C-terminal segment of rat mitochondria TOM40 constitutes protein-conducting pore with enriched2004

    • Author(s)
      Suzuki H., Kadowaki T., Maeda M., Sasaki H., et al.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 50619-50629

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Actin filaments play an essential role for transport of nascent HIV-1 proteins in host cells.2004

    • Author(s)
      Sasaki H., Ozaki H., Karaki H., Nonomura Y.
    • Journal Title

      Biochem.Biophys.Res.Commun. 316

      Pages: 588-593

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Radixin deficiency causes deafness associated with progressive degeneration of co- chlear stereocilia.2004

    • Author(s)
      S.Kitajiri, K.Fukumoto, M.Hata, H.Sasaki, et al.
    • Journal Title

      J Cell Biol 166

      Pages: 559-570

    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Establishment and characterization of cultured epithelial cells lacking expression of ZO-1.2004

    • Author(s)
      K.Umeda, T.matsui, M.Nakayama.K.Furuse, H.Sasaki et al.
    • Journal Title

      J Biol Chem 279

      Pages: 44785-44794

    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Electron tomography of fast frozen, stretched rigor ibers reveals elastic distortions in the myosin crossbridges.2004

    • Author(s)
      J.Liu, M.C.Reedy, Y.Goldman, C.Armstrong, H.Sasaki, et al.
    • Journal Title

      J Struct Biol 147

      Pages: 268-282

    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] JACOP, A novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin.2004

    • Author(s)
      Ohnishi H., Nakahara T., Sasaki H., et al.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 46014-46022

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Membrane-embedded C-terminal segment of rat mitochondria TOM40 constitutes protein-conducting pore with enriched B-structure.2004

    • Author(s)
      Suzuki H., Kadowaki T., Sasaki H., et al.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 50619-50629

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] JACOP : A novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin.2004

    • Author(s)
      H.Ohnishi, T.Nakahara, K.Furuse, H.Sasaki, et al.
    • Journal Title

      J Boil Chem 279

      Pages: 46014-46022

    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Membrane-embedded C-terminal segment of rat mitochondria TOM40 constitutes protein-conducting pore with enriched B-structure.2004

    • Author(s)
      H.Suzuki, T.Kadowaki, M.Maeda, H.Sasaki, et al.
    • Journal Title

      J Biol Chem 279

      Pages: 50619-50629

    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Establishment and characterization of cultured epithelial cells lacking expression of ZO-1.2004

    • Author(s)
      Umeda K., Matsui T., Sasaki H., et al.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 44785-44794

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia.2004

    • Author(s)
      Kitajiri S., Fukumoto K., Sasaki H., et al.
    • Journal Title

      J.Cell Biol. 166

      Pages: 559-570

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia.2004

    • Author(s)
      Kitajiri S., Fukumoto K., Hata M., Sasaki H., et al.
    • Journal Title

      J. Cell. Biol 166

      Pages: 559-570

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Actin filaments play an essential role for transport of nascent HIV-1 proteins in host cells.2004

    • Author(s)
      Sasaki H., Ozaki H., Karaki H., Nonomura Y.
    • Journal Title

      Biochem. Biophys. Res. Commun. 316

      Pages: 588-593

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Electron tomography of fast frozen, stretched rigor fibers reveals elastic distortions in the myosin crossbridges.2004

    • Author(s)
      Liu J., Reedy M.C., Goldman Y., Sasaki H., et al.
    • Journal Title

      J.Struct.Biol. 147

      Pages: 268-282

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Actin filaments play an essential role for transport of nascent HIV-1 proteins in host cells.2004

    • Author(s)
      H.Sasaki, H.Ozaki, H.Karaki, Y.Nonomura
    • Journal Title

      Biochem Biophys Res Commun 316

      Pages: 588-593

    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Electron tomography of fast frozen, stretched rigor fibers reveals elastic distortions in the myosin crossbridges.2004

    • Author(s)
      Liu J., Reedy M.C., Goldman Y., Sasaki H., et al.
    • Journal Title

      J. Struct. Biol 147

      Pages: 268-282

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] JACOP, A novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin.2004

    • Author(s)
      Ohnishi H., Nakahara T., Furuse K., Sasaki H., et al.
    • Journal Title

      J. Boil. Chem. 279

      Pages: 46014-46022

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Establishment and characterization of cultured epithelial cells lacking expression of ZO-1.2004

    • Author(s)
      Umeda K., Matsui T., Sasaki H., et al.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 44785-44794

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590155
  • [Journal Article] Dynamic behavior of paired claudin strands within apposing plasma membranes.2003

    • Author(s)
      Sasaki, H. et al.
    • Journal Title

      Proc.Natl.Acaci.Sci.USA 100

      Pages: 3971-3976

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12219210
  • [Journal Article] Dynamic behavior of paired claudin strands within apposing plasma membranes.2003

    • Author(s)
      Sasaki, H. et al.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 100

      Pages: 3971-3976

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12219210
  • [Journal Article] The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells

    • Author(s)
      Takahashi S, Iwamoto N, Sasaki H, Ohashi M, Oda Y, Tsukita S, Furuse M
    • Journal Title

      J Cell Sci (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Presentation] Beta-adrenergic stimulation enhances Ca^ leak from sarcoplasmic reticulum through protein kinase A-dependent phosphorylation of ryanodine receptor under physiological condition2010

    • Author(s)
      Morimoto S, O-Uchi J, Kawai M, Kusakari Y,Komukai K,Sasaki H, Yoshimura M, Hongo K,Kurihara S
    • Organizer
      Scientific Session of American Heart Association
    • Place of Presentation
      Chicago, IL, USA
    • Data Source
      KAKENHI-PROJECT-22300130
  • [Presentation] Tight junction maintains calcium distribution which leads to the cellular differentiation in epidermis.2010

    • Author(s)
      K Seki, M Murata, H Sasaki
    • Organizer
      The 50th American Sciety for Cell Biology Annual Meeting.
    • Place of Presentation
      Philadelphia Convention Center, (USA)
    • Year and Date
      2010-12-14
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Presentation] Epidermal tight junction maintains calcium distribution in human recorfstructed epidermis and regulates the epidermal differentiation.2010

    • Author(s)
      H Sasaki, T Maeda, S Kuroda, M Kurasawa, A Oba, T Yamamoto
    • Organizer
      The 40th Annual European Society for Dermatological Research meeting
    • Place of Presentation
      Helsinki Marina Congress Center, (Finland)
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PLANNED-22136002
  • [Presentation] β-Adrenoceptor stimulation increased Ca2+ leak from sarcoplasmic reticulum without dissociation of FKBP12. 6 under physiological condition2009

    • Author(s)
      Morimoto S, O-uchi J, Kawai M, Komukai K, Sasaki H, Yoshimura M, Hongo K, Kurihara S
    • Organizer
      The XXXVI International Congress of Physiological Sciences
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19500357
  • [Presentation] 3細胞結合領域に局在する新規膜内在性タンパク質の同定と解析2009

    • Author(s)
      増田小百合、佐々木博之、池ノ内順一、西英一郎、古瀬幹夫
    • Organizer
      第61回日本細胞生物学会大会・第81回日本生化学会大会合同大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Presentation] β-Adrenoceptor stimulation increased Ca leak from sarcoplasmic reticulum without dissociation of FKBP12.6 under physiological condition.2009

    • Author(s)
      Morimoto S, O-uchi J, Kawai M, Komukai K, Sasaki H, Yoshimura M, Hongo K, Kurihara S
    • Organizer
      The XXXVI International Congress of Physiological Sciences
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19500357
  • [Presentation] The E3 ubiquitin ligase LNX-1 downregulates claudins from tight junctions2008

    • Author(s)
      岩本典子、高橋千絵、佐々木博之、月田承一郎、古瀬幹夫
    • Organizer
      第31回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Presentation] The E3 ubiquitin ligase LNX-1 downregulates claudins from tight junctions2008

    • Author(s)
      Takahashi S, Iwamoto N, Sasaki H, Tsukita S, Furuse M
    • Organizer
      48th The American Society for Cell Biology Annual Meeting
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2008-12-13
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Presentation] The E3 ubiquitin ligase LNX-1 downregulates claudins from tight junctions2008

    • Author(s)
      Iwamoto N, Takahashi S, Sasaki H, Tsukita S, Furuse M
    • Organizer
      Gordon Research Conference : SIGNALING BY ADHESION RECEPTORS
    • Place of Presentation
      South Hadley, Massachusetts, USA
    • Year and Date
      2008-06-29
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Presentation] E3ユビキチンリガーゼLNX1によるクローディンのタイトジャンクションからの消失2008

    • Author(s)
      高橋千絵、岩本典子、佐々木博之、月田承一郎、古瀬幹夫
    • Organizer
      第60回日本細胞生物学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Presentation] The E3 ubiquitin ligase LNX-1 downregulates claudins from tight junctions.2008

    • Author(s)
      Iwamoto N, Takahashi S, Sasaki H, Tsukita S, Furuse M.
    • Organizer
      Gordon Research Conference: SIGNALING BY ADHESION RECEPTORS.
    • Place of Presentation
      South Hadley, USA
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Presentation] The E3 ubiquitin ligase LNX-1 downregulates claudins from tight junctions.2008

    • Author(s)
      Takahashi S, Iwamoto N, Sasaki H, Tsukita S, Furuse M.
    • Organizer
      48th The American Society for Cell Biology Annual Meeting.
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Presentation] クローディン15ノックアウトマウスにおける小腸肥大化の解析2007

    • Author(s)
      田村淳、北野由佳、秦正樹、勝野達也、森脇一将、佐々木博之、野田哲生、古瀬幹夫、月田承一郎、月田早智子
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Presentation] Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.2006

    • Author(s)
      Ikenouchi J, Furuse M, Furuse K, Sasaki H, Tsukita Sa, Tsukita Sh.
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology.
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-17014044
  • [Presentation] Overlapping and distinct functions of two jomologous, PDZ domain-containing tight junction proteins, MUPP-1 and Patj.2006

    • Author(s)
      Adachi, M, Hamazaki Y, Kobayashi Y, Itoh M, Sasaki H, Takai Y, Furuse M, Tsukita S.
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology.
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-17014044
  • 1.  TSUKITA Sachiko (00188517)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 19 results
  • 2.  TAMURA Atsushi (00362525)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 3.  MORIMOTO Sachio (50202362)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 4.  FURUSE Mikio (90281089)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 19 results
  • 5.  ADACHI Makoto (30335244)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  KUBO Akiharu (70335256)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KURIHARA Satoshi (90057026)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 8.  HONGO Kenichi (00256447)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 9.  KOMUKAI Kimiaki (60360145)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 10.  ODA Yukako (70452498)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 11.  FUKUDA Norio (30301534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MATSUI Takeshi (10452442)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TAKEUCHI Kosei (90206946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  YAMAZAKI Yuji (80527664)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Kurachi Yoshihisa (30142011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  INANOBE Atsushi (00270851)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  ASAI Yoshiyuki (00415639)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  FURUTANI Kazuharu (40452437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  TSUMOTO Kunichika (70353331)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NOMURA Taishin (50283734)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  KUSAKARI Yoichiro (80338889)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  TSUKITA Shoichiro (50155347)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  YAMAMOTO Toshio (30107776)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KAWAI Mariko (40379839)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  中尾 和貴 (20217657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  AitHaddou Rachid (50506574)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  伊藤 雅彦 (70270486)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  米村 重信 (60192811)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  永渕 昭良 (80218023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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