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IHARA Makoto  井原 誠

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… Alternative Names

井原 誠  イハラ マコト

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Researcher Number 60175213
External Links
Affiliation (Current) 2025: 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員
Affiliation (based on the past Project Information) *help 2022 – 2023: 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員
2013 – 2016: 長崎大学, 原爆後障害医療研究所, 助教
2012: 長崎大学, 医歯(薬)学総合研究科, 助教
2009: 長崎大学, 医歯薬学総合研究科, 助教
2006: Nagasaki University, Graduate School of Biomedical Sciences, Assistant Professor, 大学院医歯薬学総合研究科, 助手 … More
2003 – 2005: Nagasaki University, Graduated School of Biochemical Sciences, Assistant Professor, 大学院・医歯薬学総合研究科, 助手
1995 – 2002: 長崎大学, 医学部, 助手
1988: 奈良医科大学, 研究員 Less
Review Section/Research Field
Principal Investigator
Radiation science
Except Principal Investigator
Radiation science / Risk sciences of radiation/Chemicals / Radiation science / Medium-sized Section 63:Environmental analyses and evaluation and related fields / 環境影響評価(含放射線生物学)
Keywords
Principal Investigator
Ku70 / DNA-PK / HSC73 / Ku80 / 熱ショック蛋白質 / 温熱処理 / 80 / Heat shock Protein / Recovery of hea-inactivation / Heat shock protein … More / 熱失活の回復 / Heat treatment / DNA double strand break / X線 / DNA二本鎖切断の修復 / DNA-PK活性 / DNA二本鎖切断 … More
Except Principal Investigator
p53 / 放射線感受性 / RBE / 変異部位 / アポトーシス / 放射線治療 / 放射線耐性 / 癌治療 / XRCC / DNA-PK / MTF-1 / ATM / 細胞周期 / ERK / FAK / scid cells / DNA-PK activity / DNA double strand breaks / radiosensitivity / heavy ion particles / DNA-PK活性 / DNA二重鎖切断 / 重粒子線 / scid細胞 / 突然変異 / Saos-2 / 放射線リスク / DNA修復モデル / BLQモデル / 放射線突然変異 / 非相同末端再結合 / 相同組換え修復 / cell cycle / DNA repair / radiation / thyroid / 甲状腺がん / MDM2 / DNA修復 / 放射線 / 甲状腺 / laminin / integrin / X-ray / metastasis / cell mobility / P53 / 神経膠芽腫細胞 / 放射線照射 / 細胞外マトリックス / 癌転移 / ラミニン / インテグリン / X線 / がん転移 / 細胞運動性 / DNA二重鎖 / transduction / apoptosis / signal transduction / radio-sensitivity / mutation / SaOS-2 / G1停止 / シグナル伝達 / Saos2 / 遺伝子導入 / シグナルトランスダクション / DNAニ重鎖切断 / NIH3T3 Cells / Thermosensitivity / Oncogene / NIH3T3細胞 / 熱感受性 / 癌遺伝子 / 活性中心 / 部位特異的突然変異誘発 / 光吸収体 / シクロブタン型ピリミジン二量体 / 光回復酵素 / 腫瘍浸潤 / FDG PET / テーラーメイド医療 / 膵癌 / 核医学 / リスクコミュニケーション / 福島原発事故 / 分子イメージング / 放射性ヨウ素 / 内部被ばく / メチルメタンスルフォン酸 / 修復間違い / 除去修復 / 光回復 / Polymerase I / 紫外線 / 損傷乗り越え複製 Less
  • Research Projects

    (16 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (18 People)
  •  DNA修復細胞集団の再構成に伴う低線量放射線リスクの上振れ

    • Principal Investigator
      小松 賢志
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 63:Environmental analyses and evaluation and related fields
    • Research Institution
      Kyoto University
  •  Development of patient specific medicine using FDG PET and gene expression

    • Principal Investigator
      KUDO Takashi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Nagasaki University
  •  Evaluation of health risk of internal exposure with radioactive iodine by molecular imaging

    • Principal Investigator
      MATSUDA Naoki
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Nagasaki University
  •  紫外線誘発突然変異は除去修復ギャップの修復複製で生じる

    • Principal Investigator
      山本 和生
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Tohoku University
  •  Study of Involvement of DNA Repair in Radiation Induced Thyroid Cancer

    • Principal Investigator
      ASHIZAWA Kiyoto
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Radiation Effects Research Foundation
  •  Effect of X-ray irradiation on tumor metastasis

    • Principal Investigator
      MATSUDA Naoki, 奥村 寛
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Nagasaki University
  •  Role of heat shock protein (HSP) for the recovery of heat-inactivated DNA-PKPrincipal Investigator

    • Principal Investigator
      MAKOTO Ihara
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Nagasaki University
  •  Radiosensitivity of Scid Cells Deficient in Repair of DNA Damages Induced by High LET Irradiation

    • Principal Investigator
      OKUMURA Yutaka
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Nagasaki University
  •  p53の変異部位に対応した放射線による癌治療法の開発

    • Principal Investigator
      岡市 協生
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagasaki University
  •  p53の変異部位に対応した放射線による癌治療法の開発

    • Principal Investigator
      岡市 協生
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagasaki University
  •  Relationship between DNA double strand break repair and DNA-PK activityPrincipal Investigator

    • Principal Investigator
      IHARA Makoto
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Nagasaki University
  •  p53の変異部位に対応した放射線による癌治療法の開発

    • Principal Investigator
      OKAICHI Kumio
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagasaki University
  •  Radiosensitivity of scid cells for heavy ion particles

    • Principal Investigator
      OKUMURA Yutaka
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      NAGASAKI UNIVERSITY
  •  The changes of radio-sensitivity and signal transduction by mutation in p53

    • Principal Investigator
      OKAICHI Kumio
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Nagasaki University
  •  Analysis of Thermotolerance of Cancer by Introduction of Oncogeges

    • Principal Investigator
      OKUMURA Yutaka
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Nagasaki University
  •  大腸菌光回復酵素遺伝子の構造と酵素の機能

    • Principal Investigator
      山本 和生
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka Prefectural Institute of Public Health

All 2016 2015

All Presentation

  • [Presentation] DNA二重鎖切断修復過程に働くATMの線量依存性2016

    • Author(s)
      井原誠, 斉藤裕一郎, 小林純也, 栗政明弘, 工藤崇
    • Organizer
      日本放射線影響学会第59回大会
    • Place of Presentation
      JMSアステールプラザ(広島県・広島市)
    • Year and Date
      2016-10-26
    • Data Source
      KAKENHI-PROJECT-26461857
  • [Presentation] Association of ATM with the rejoining of DNA double-strand breaks in cells lacking non-homologous end-joining2015

    • Author(s)
      Makoto Ihara
    • Organizer
      15th International Congress of Radiation Research
    • Place of Presentation
      京都国際会議場(京都府・京都市)
    • Year and Date
      2015-05-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461857
  • 1.  OKUMURA Yutaka (00073130)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  OKAICHI Kumio (80124874)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  MATSUDA Naoki (00304973)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KUDO Takashi (20330300)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  山本 和生 (20093536)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  NAKAYAMA Morio (60164373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SIMASAKI Tatsuya (60264248)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  TAKESHITA Satoshi (20295083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MORITA Naoko (90380972)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ASHIZAWA Kiyoto (10304932)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  NANBA Hiroyuki (80237635)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  吉田 正博 (50264247)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  福岡 順也 (00324575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  上谷 雅孝 (40176582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  七島 篤志 (60380838)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  山下 俊一 (30200679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  小松 賢志 (80124577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  田内 広 (70216597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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