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Kasai Haruo  河西 春郎

… Alternative Names

KASAI Haruo  河西 春郎

KASSAI Haruo  葛西 春郎

河西 春郎  カサイ ハルオ

Less
Researcher Number 60224375
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-2327-9027
Affiliation (Current) 2025: 東京大学, ニューロインテリジェンス国際研究機構, 特任教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 東京大学, ニューロインテリジェンス国際研究機構, 特任教授
2020 – 2021: 東京大学, 大学院医学系研究科(医学部), 教授
2016 – 2018: 東京大学, 大学院医学系研究科(医学部), 教授
2016: 東京大学, 大学院医学系研究科, 教授
2014 – 2015: 東京大学, 医学(系)研究科(研究院), 教授 … More
2014: 東京大学, 医学(系)研究科(研究院), 教授
2013 – 2014: 東京大学, 大学院医学系研究科, 教授
2011 – 2012: 東京大学, 医学(系)研究科(研究院), 教授
2007 – 2010: The University of Tokyo, 大学院・医学系研究科, 教授
2006: 東京大学, 大学院医学系研究科, 教授
2005: 東京大学, 大学院・医学系研究科, 教授
2004: 生理学研究所, 教授
2004: 生理学研究所, 細胞器官研究系, 教授
2000 – 2003: 岡崎国立共同研究機構, 生理学研究所, 教授
1999: PROFESSOR, NATIONAL INSTITUTE OF PHYSIOLOGICAL SCIENCES, 細胞器官研究系, 教授
1998: Okazaki, NATIONAL INSTITUTh OF PHYSIOLOGICAL SCIENCES, PROFESSOR, 生理学研究所, 教授
1998: 東京大学, 大学院医学系研究科, 助教授
1997 – 1998: 東京大学, 大学院・医学系研究科, 助教授
1996: 東京大学, 医学部, 助教授
1995: Dept.physiol., Facult.Med., Univ.Tokyo, Associate Professor, 医学部・第一生理, 助教授
1994 – 1995: 東京大学, 医学部(医), 助教授
1994: 東京大学, 医学部, 助教授
1991: 東京大学, 医学部(医), 助手 Less
Review Section/Research Field
Principal Investigator
Broad Section G / General physiology / Neurophysiology / General neuroscience / Biological Sciences / Neuroscience in general / Biological Sciences / Medium-sized Section 46:Neuroscience and related fields / 神経・脳内生理学
Except Principal Investigator
Biological Sciences / Neurophysiology / General neuroscience … More / Biological Sciences / General physiology / General physiology / Functional biochemistry Less
Keywords
Principal Investigator
シナプス / ケイジド試薬 / 樹状突起スパイン / 生理学 / シグナル伝達 / 2光子励起 / グルタミン酸受容体 / 学習 / スパイン / 学習・記憶 … More / 開口放出 / 脳・神経 / 糖尿病 / 生物・生体工学 / カルシウム / メカノバイオロジー / 記憶 / Exocrine gland / 外分泌腺 / 精神疾患 / スパインシナプス / ドーパミン / グルタミン酸 / 学習記憶 / 神経回路 / 知能 / 情動 / アクチン繊維 / 作業記憶 / シナプス化学遺伝学 / 蛍光プローブ / 2光子顕微鏡 / 光プローブ / 光刺激 / D2受容体 / 精神症状 / 条件学習 / 蛋白質合成 / 大脳基底核 / 大脳皮質 / synapse / caged compounds / two-photon excitation / glutamate receptor / High performance laser / Two-photon microscope / Signal transduction / Physiology / 急性膵炎 / 膵臓外分泌腺 / 塩素イオンチャネル / 溶液輸送 / アクチン / ケージド試薬 / 2光子顕微鏡 / 高性能レーザー / 2光子励起顕微鏡 / Caged compounds / Acetylcholine / Zymogeu granule / Patch Clamp / Exocytosis / Calcium / イオンチャネル / カルシウム(Ca) / 分泌顆粒 / アセチハコリン / パッチクランプ / 膵臓腺細胞 / カルシウムシグナル / ヘブ学習 / 強化学習 / 分泌 / 顕微鏡 / 2光子励起 / 小脳 / グルタメイト / 画像処理 / Ca画像処理 / シナプス剤終末 / レ-ザ-顕微鏡 … More
Except Principal Investigator
シナプス可塑性 / 2光子励起顕微鏡 / ケイジド試薬 / 受容体 / 神経可塑性 / 樹状突起スパイン / lipid mediators / シグナル伝達 / 脂質メディエーター / ノックアウトマウス / 高性能レーザー / スパイン / 生理学 / 標的遺伝子組み換え / 2光子顕微鏡 / プレシナプス / 2光子顕微鏡 / FRET / 蛍光寿命画像顕微鏡 / 逆行性情報伝達 / スパイン形態可塑性 / シナプス / 機械的刺激 / 逆行性シグナル / プレシナプスブトン / シナプス刈り込み / Synaptic optogenetics / DISC1 / AS-PaRac1 / Functional connectomics / 精神疾患 / シナプス光遺伝学 / 統合失調症 / 2光子イメージング / phospholipases / protein kinase C / 低分子量Gタンパク質 / プロスタノイド / グリア細胞 / Miller-Dieker / ホスホリパーゼA_2 / 開口放出 / 無脳回症 / 低分子量Gタンパク / プロスタグランジン / 血小板活性化因子 / ホスホリパーゼ / プロテインキナーゼC / NMDA receptor / Knockout mice / Synaptic plasticity / リン酸化酵素 / Gタンパク質 / グルタイン酸受容体 / 若手研究者 / 班会議 / 公開シンポジウム / 記憶 / NMDA受容体 / 細胞 / 可視化 / 糖尿病 / 細胞・組織 / 細胞生理学 / 長期観察 / グルタミン酸 / 超短パルスレーザー / 神経生理学 / 中枢神経細胞 / グルタミン酸受容体 / 2光子励起 / 外分泌腺 / チャネルゲート / 細胞内情報伝達 / トランスポーター / イオンチャネル / 転写制御 / 血管平滑筋 / GFP / cAMP / 蛍光カルシウム指示薬 / 受精 / 分泌 / 膵臓β細胞 / イノシトール三燐酸 / カルシウム / 可塑性遺伝子 / 可塑性情報 Less
  • Research Projects

    (26 results)
  • Research Products

    (231 results)
  • Co-Researchers

    (41 People)
  •  大脳スパインシナプス力学伝達の統合的な解析とシナプス化学遺伝学の創始Principal Investigator

    • Principal Investigator
      河西 春郎
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section G
    • Research Institution
      The University of Tokyo
  •  From the structure-function relationship of dendrtic spines to synaptic mechanobiologyPrincipal Investigator

    • Principal Investigator
      河西 春郎
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section G
    • Research Institution
      The University of Tokyo
  •  From structural plasticity of dendritic spines to synaptic mechano-biologyPrincipal Investigator

    • Principal Investigator
      河西 春郎
    • Project Period (FY)
      2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 46:Neuroscience and related fields
    • Research Institution
      The University of Tokyo
  •  大脳の記憶シナプスの2光子顕微鏡と新規光プローブとを用いた研究Principal Investigator

    • Principal Investigator
      河西 春郎
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurophysiology / General neuroscience
    • Research Institution
      The University of Tokyo
  •  Study of cerebral synapses and circuits using two-photon microscopy and novel optoprobesPrincipal Investigator

    • Principal Investigator
      Kasai Haruo
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Neurophysiology / General neuroscience
    • Research Institution
      The University of Tokyo
  •  Analysis of the properties of synaptic back propagating signal

    • Principal Investigator
      NOGUCHI Jun
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology / General neuroscience
    • Research Institution
      National Center of Neurology and Psychiatry
      The University of Tokyo
  •  The dendritic spine as the microendophenotype of psychiatric disorders

    • Principal Investigator
      Hayashi-Takagi Akiko
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
      The University of Tokyo
  •  大脳棘シナプスと分泌現象の2光子顕微鏡による研究Principal Investigator

    • Principal Investigator
      河西 春郎
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neuroscience in general
    • Research Institution
      The University of Tokyo
  •  Cerebral spine synapses and exocytosis studied with two-photon microscopePrincipal Investigator

    • Principal Investigator
      KASAI Haruo
    • Project Period (FY)
      2009 – 2014
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Analysis of endocrine pancreas using two-photon excitation imaging

    • Principal Investigator
      TAKAHASHI Noriko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      The University of Tokyo
  •  Dynamics of synapse and exocytosis studied with two-photon excitationPrincipal Investigator

    • Principal Investigator
      KASSAI Haruo
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
      National Institute for Physiological Sciences
  •  2光子励起ケイジドグルタミン酸を用いた樹状突起スパイン形態・機能の可塑性の研究

    • Principal Investigator
      MATSUZAKI Masanori
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Okazaki National Research Institutes
  •  2光子励起ケイジドグルタミン酸を用いたシナプス結合形態・機能の動態と可塑性の研究

    • Principal Investigator
      松崎 政紀
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute for Physiological Sciences
      Okazaki National Research Institutes
  •  2光子励起顕微鏡法を用いたシナプス・開口放出機構の研究Principal Investigator

    • Principal Investigator
      河西 春郎
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Neuroscience in general
    • Research Institution
      National Institute for Physiological Sciences
      Okazaki National Research Institutes
  •  2光子励起法とケイジド試薬を用いたグルタミン酸受容体の機能分布・動態の可視化Principal Investigator

    • Principal Investigator
      河西 春郎
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Okazaki National Research Institutes
  •  2光子励起ケイジドグルタミン酸を用いた樹状突起スパイン機能の研究

    • Principal Investigator
      NEMOTO Tomomi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Okazaki National Research Institutes
  •  Mechanisms of secretion studied with two-photon excitation imaging and uncagingPrincipal Investigator

    • Principal Investigator
      NEMOTO Tomomi, 河西 春郎
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute for Physiological Sciences
      Okazaki National Research Institutes
  •  Investigation of Ca-dependent cellular functions with caged compoundsPrincipal Investigator

    • Principal Investigator
      KASAI Haruo
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      OKAZAKI NATIONAL RESEARCH INSTITUTES
  •  細胞内情報伝達の生理機能解析と情報分子の可視化

    • Principal Investigator
      飯野 正光
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  イオンチャネル及び膜受容体の信号伝達による細胞機能発現機構の生理学的意義

    • Principal Investigator
      瀬山 一正
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Hiroshima University
  •  Molecular mechanism of synaptic plasticity

    • Principal Investigator
      SHIMIZU Takao
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Molecular mechanism of synaptic plasticity

    • Principal Investigator
      SHIMIZU Takao
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  神経可塑性の分子機構に関する総合研究

    • Principal Investigator
      SHIMIZU Takao
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokyo
  •  A study of exocrine cell functions using local photolysis of caged compounds.Principal Investigator

    • Principal Investigator
      KASAI Haruo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      The University of Tokyo
  •  シナプス前終末マクティブソンシのCa濃度変化の高速測定Principal Investigator

    • Principal Investigator
      河西 春郎
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      神経・脳内生理学
    • Research Institution
      The University of Tokyo
  •  中枢神経シナプス剤終末カルシウム濃度のレ-ザ-顕微鏡を用いた直接測定Principal Investigator

    • Principal Investigator
      河西 春郎
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2000 Other

All Journal Article Presentation Book Patent

  • [Book] The islet of Langerhans.2009

    • Author(s)
      Kasai, H.
    • Total Pages
      554
    • Publisher
      Springer Verlag, New York
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Book] cAMPによるインスリン分泌増強機構「新時代の糖尿病学(1)」(66巻増刊号3)2008

    • Author(s)
      高橋倫子, 河西春郎
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Book] 膵島における開口放出のイメージング「BIOCLINICA」(22巻6号)2007

    • Author(s)
      高橋倫子, 河西春郎
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Book] インスリン開口放出の評価法「内分泌・糖尿病科」(25巻3号)2007

    • Author(s)
      高橋倫子, 河西春郎
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Book] インスリン分泌における開口分泌機構-2光子励起画像法による検出「カラー版 糖尿病学 -基礎と臨床-」2007

    • Author(s)
      畠山裕康, 高橋倫子, 河西春郎
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Book] Two-photon excitation imaging of insulin exocytosis. Pancreatic beta cell in health and disease2007

    • Author(s)
      Takahashi N., Kasai H.
    • Publisher
      Springer Verlag
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Book] インスリン分泌 第1章「インシュリン開口放出現象の可視化から何がわかるか」pp.39-422004

    • Author(s)
      畠山裕康, 高橋倫子, 根本知己, 河西春郎
    • Total Pages
      195
    • Publisher
      文光堂(東京)
    • Data Source
      KAKENHI-PROJECT-12144209
  • [Journal Article] Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment2023

    • Author(s)
      Hagiwara, H., Hirotaka, S.,…, Kasai, H. (29 th author out of 131 authors), …, Miyakawa, T.
    • Journal Title

      eLife

      Volume: 12

    • DOI

      10.7554/elife.89376.1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Journal Article] シナプス構造可塑性:現在と未来.2023

    • Author(s)
      72.河西春郎
    • Journal Title

      生体の科学

      Volume: 74 Pages: 51-56

    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Journal Article] Unraveling the mysteries of dendritic spine dynamics: Five key principles shaping memory and cognition2023

    • Author(s)
      Kasai, H.
    • Journal Title

      Proceedings of the Japan Academy, Series B

      Volume: 99 Issue: 8 Pages: 254-305

    • DOI

      10.2183/pjab.99.018

    • ISSN
      0386-2208, 1349-2896
    • Year and Date
      2023-10-11
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Journal Article] Mechanical transmission at spine synapses: Short-term potentiation and working memory2023

    • Author(s)
      Haruo Kasai, Hasan Ucar, Yuichi Morimoto, Fumihiro Eto, Hitoshi Okazaki
    • Journal Title

      Current Opinion in Neurobiology

      Volume: 80 Pages: 102706-102706

    • DOI

      10.1016/j.conb.2023.102706

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15203, KAKENHI-PROJECT-20H05685
  • [Journal Article] Tri-view two-photon microscopic image registration and deblurring with convolutional neural networks2022

    • Author(s)
      Lee Sehyung、Kume Hideaki、Urakubo Hidetoshi、Kasai Haruo、Ishii Shin
    • Journal Title

      Neural Networks

      Volume: 152 Pages: 57-69

    • DOI

      10.1016/j.neunet.2022.04.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K12062, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-19H04180, KAKENHI-PLANNED-17H06310, KAKENHI-PROJECT-22H04998
  • [Journal Article] The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal.2021

    • Author(s)
      Urakubo H, Yagishita S, Kasai H, Kubota Y, Ishii S
    • Journal Title

      PLoS Comput Biol

      Volume: 17 Issue: 9 Pages: e1009364-e1009364

    • DOI

      10.1371/journal.pcbi.1009364

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03336, KAKENHI-PUBLICLY-21H00217, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-20K12062, KAKENHI-PLANNED-17H06310, KAKENHI-PLANNED-17H06311
  • [Journal Article] Forceful synapses reveal mechanical interactions in the brain.2021

    • Author(s)
      Kasai, H. & Ucar, H.
    • Journal Title

      Nature

      Volume: 600 Pages: 2021-2021

    • DOI

      10.1038/d41586-021-03516-0

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-21K15203
  • [Journal Article] Mechanical actions of dendritic-spine enlargement on presynaptic exocytosis2021

    • Author(s)
      Ucar Hasan、Watanabe Satoshi、Noguchi Jun、Morimoto Yuichi、Iino Yusuke、Yagishita Sho、Takahashi Noriko、Kasai Haruo
    • Journal Title

      Nature

      Volume: 600 Issue: 7890 Pages: 686-689

    • DOI

      10.1038/s41586-021-04125-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-21H05176, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-21H02594, KAKENHI-PROJECT-20K07280, KAKENHI-PROJECT-21K15203
  • [Journal Article] Spine dynamics in the brain, mental disorders and artificial neural networks2021

    • Author(s)
      Kasai Haruo、Ziv Noam E.、Okazaki Hitoshi、Yagishita Sho、Toyoizumi Taro
    • Journal Title

      Nature Reviews Neuroscience

      Volume: 22 Issue: 7 Pages: 407-422

    • DOI

      10.1038/s41583-021-00467-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05432, KAKENHI-PROJECT-20H05685
  • [Journal Article] Computational roles of intrinsic synaptic dynamics2021

    • Author(s)
      Shimizu Genki、Yoshida Kensuke、Kasai Haruo、Toyoizumi Taro
    • Journal Title

      Current Opinion in Neurobiology

      Volume: 70 Pages: 34-42

    • DOI

      10.1016/j.conb.2021.06.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05432, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-21J10564
  • [Journal Article] Mu-net: Multi-scale U-net for two-photon microscopy image denoising and restoration2020

    • Author(s)
      Lee Sehyung、Negishi Makiko、Urakubo Hidetoshi、Kasai Haruo、Ishii Shin
    • Journal Title

      Neural Networks

      Volume: 125 Pages: 92-103

    • DOI

      10.1016/j.neunet.2020.01.026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K00404, KAKENHI-PROJECT-20H05685
  • [Journal Article] Generative and discriminative model-based approaches to microscopic image restoration and segmentation2020

    • Author(s)
      Ishii Shin、Lee Sehyung、Urakubo Hidetoshi、Kume Hideaki、Kasai Haruo
    • Journal Title

      Microscopy

      Volume: 69 Pages: 79-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H00480
  • [Journal Article] Signaling models for dopamine-dependent temporal contiguity in striatal synaptic plasticity2020

    • Author(s)
      Hidetoshi Urakubo, Sho Yagishita, Haruo Kasai, Shin Ishii
    • Journal Title

      PLoS Computational Biology

      Volume: 16 Issue: 7 Pages: 1008078-1008078

    • DOI

      10.1371/journal.pcbi.1008078

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K12062, KAKENHI-PLANNED-17H06310, KAKENHI-PROJECT-20H00480, KAKENHI-PROJECT-17K00404, KAKENHI-PROJECT-19K16249, KAKENHI-PLANNED-16H06396
  • [Journal Article] Dopamine D2 receptors in discrimination learning and spine enlargement2020

    • Author(s)
      Iino Yusuke、Sawada Takeshi、Yamaguchi Kenji、Tajiri Mio、Ishii Shin、Kasai Haruo、Yagishita Sho
    • Journal Title

      Nature

      Volume: 579 Issue: 7800 Pages: 555-560

    • DOI

      10.1038/s41586-020-2115-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-INTERNATIONAL-16K21720, KAKENHI-PLANNED-16H06396, KAKENHI-PROJECT-18J21753, KAKENHI-PROJECT-18J21845, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-19K16249
  • [Journal Article] Computational Characteristics of the Striatal Dopamine System Described by Reinforcement Learning With Fast Generalization2020

    • Author(s)
      Fujita Yoshihisa、Yagishita Sho、Kasai Haruo、Ishii Shin
    • Journal Title

      Frontiers in Computational Neuroscience

      Volume: 14 Pages: 66-66

    • DOI

      10.3389/fncom.2020.00066

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00480, KAKENHI-PROJECT-19K16249, KAKENHI-PLANNED-16H06396
  • [Journal Article] Dual-Component Structural Plasticity Mediated by αCaMKII Autophosphorylation on Basal Dendrites of Cortical Layer 2/3 Neurones2020

    • Author(s)
      Seaton Gillian、Hodges Gladys、de Haan Annelies、Grewal Aneesha、Pandey Anurag、Kasai Haruo、Fox Kevin
    • Journal Title

      The Journal of Neuroscience

      Volume: 40 Issue: 11 Pages: 2228-2245

    • DOI

      10.1523/jneurosci.2297-19.2020

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Journal Article] Melanophilin accelerates insulin granule fusion without predocking to the plasma membrane.2020

    • Author(s)
      Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T.
    • Journal Title

      Diabetes

      Volume: 69 Issue: 12 Pages: 2655-2666

    • DOI

      10.2337/db20-0069

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07280, KAKENHI-PROJECT-20K08796, KAKENHI-PROJECT-20K08866, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-20H00480, KAKENHI-PROJECT-19H03449, KAKENHI-PROJECT-20K15742
  • [Journal Article] Generative and discriminative model-based approaches to microscopic image restoration and segmentation2020

    • Author(s)
      Ishii Shin、Lee Sehyung、Urakubo Hidetoshi、Kume Hideaki、Kasai Haruo
    • Journal Title

      Microscopy

      Volume: 69 Issue: 2 Pages: 79-91

    • DOI

      10.1093/jmicro/dfaa007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K00404, KAKENHI-PLANNED-17H06310, KAKENHI-PROJECT-20H05685
  • [Journal Article] Strong stimulation triggers full fusion exocytosis and very slow endocytosis of the small dense core granules in carotid glomus cells.2018

    • Author(s)
      Tse A, Lee AK, Takahashi N, Gong A, Kasai H, Tse FW.
    • Journal Title

      J Neurogenet

      Volume: 32 Issue: 3 Pages: 267-278

    • DOI

      10.1080/01677063.2018.1497629

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08530, KAKENHI-PROJECT-26221001
  • [Journal Article] In Vivo Volume Dynamics of Dendritic Spines in the Neocortex of Wild-Type and Fmr1 KO Mice.2018

    • Author(s)
      Ishii K, Nagaoka A, Kishida Y, Okazaki H, Yagishita S, Ucar H, Takahashi N, Saito N, Kasai H.
    • Journal Title

      eNeuro

      Volume: 5 Issue: 5 Pages: 1-13

    • DOI

      10.1523/eneuro.0282-18.2018

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08530, KAKENHI-PROJECT-26221001, KAKENHI-PLANNED-16H06396
  • [Journal Article] Calcineurin knockout mice show a selective loss of small spines2018

    • Author(s)
      Okazaki H, Hayashi-Takagi A, Nagaoka A, Negishi M, Ucar H, Yagishita S, Ishii K, Toyoizumi T, Kasai H
    • Journal Title

      Neuroscience Letters

      Volume: 671 Pages: 99-102

    • DOI

      10.1016/j.neulet.2018.02.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293260, KAKENHI-PUBLICLY-17H05735, KAKENHI-PLANNED-18H05433, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-17K19438, KAKENHI-PLANNED-16H06396
  • [Journal Article] Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents.2018

    • Author(s)
      Tainaka K, Murakami TC, Susaki EA, Shimizu C, Saito R, Takahashi K, Hayashi-Takagi A, Sekiya H, Arima Y, Nojima S, Ikemura M, Ushiku T, Shimizu Y, Murakami M, Tanaka KF, Iino M, Kasai H, Sasaoka T, Kobayashi K, Miyazono K, Morii E, Isa T, Fukayama M, Kakita A, Ueda HR.
    • Journal Title

      Cell Rep.

      Volume: 24 Issue: 8 Pages: 2196-2210

    • DOI

      10.1016/j.celrep.2018.07.056

    • NAID

      120006542018

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19373, KAKENHI-PROJECT-18K19419, KAKENHI-PROJECT-18K14915, KAKENHI-PUBLICLY-17H05680, KAKENHI-PUBLICLY-17H05688, KAKENHI-PUBLICLY-17H05735, KAKENHI-PLANNED-17H06328, KAKENHI-PUBLICLY-18H04543, KAKENHI-PUBLICLY-18H04937, KAKENHI-ORGANIZER-18H05428, KAKENHI-PLANNED-18H05433, KAKENHI-PROJECT-18H05270, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26221003, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-18H02105, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02545, KAKENHI-PROJECT-15H05650, KAKENHI-PROJECT-16J05041, KAKENHI-PROJECT-17K19438, KAKENHI-PROJECT-25221304, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-17H06326
  • [Journal Article] Engineering Pak1 allosteric switches2017

    • Author(s)
      Dagliyan, O., Karginov, A., Yagishita, S., Gale, M., Wang, H., DerMardirossian, C., Wells, C., Dokholyan, N., Kasai, H. & Hahn, K.
    • Journal Title

      ACS Synthetic Biology

      Volume: 6 Issue: 7 Pages: 1257-1262

    • DOI

      10.1021/acssynbio.6b00359

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Journal Article] Fast 3D visualization of endogenous brain signals with high-sensitivity laser scanning photothermal microscopy2016

    • Author(s)
      J. Miyazaki, T.Iida, S. Tanaka, A. Hayashi-Takagi, H. Kasai, S. Okabe, and T. Kobayashi
    • Journal Title

      Biomed. Opt. Express

      Volume: 7 Issue: 5 Pages: 1702-1710

    • DOI

      10.1364/boe.7.001702

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K17735, KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116003, KAKENHI-PLANNED-25117006, KAKENHI-PROJECT-26250014, KAKENHI-PROJECT-26293260, KAKENHI-PROJECT-15K18360
  • [Journal Article] Abnormal intrinsic dynamics of dendritic spines in a fragile X syndrome mouse model in vivo.2016

    • Author(s)
      Nagaoka A, Takehara H, _Hayashi-Takagi A_, Noguchi J, Ishii K, Shirai F, Yagishita S, Akagi T, Ichiki T, Kasai H.
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 26651-26651

    • DOI

      10.1038/srep26651

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116003, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26293260, KAKENHI-PROJECT-26430005
  • [Journal Article] Implantable Microfluidic Device with Hydrogel Permeable Membrane for Delivering Chemical Compounds and Imaging Neural Cells in Living Mice2016

    • Author(s)
      Takehara, H., Nagaoka, A., Noguchi, J., Akagi, T., Kasai, H. & Ichiki, T.
    • Journal Title

      J. Photopol. Sci. Technol.

      Volume: 29 Issue: 4 Pages: 513-518

    • DOI

      10.2494/photopolymer.29.513

    • NAID

      130005261780

    • ISSN
      0914-9244, 1349-6336
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26430005
  • [Journal Article] Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells2016

    • Author(s)
      Masataka Kunii, et al,
    • Journal Title

      J. Cell Biol.

      Volume: 215 Issue: 1 Pages: 121-138

    • DOI

      10.1083/jcb.201604030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05953, KAKENHI-PLANNED-26110003, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26242082, KAKENHI-PROJECT-15H04668, KAKENHI-PROJECT-26291036, KAKENHI-PROJECT-26350976, KAKENHI-PROJECT-26460290, KAKENHI-PROJECT-15K19525, KAKENHI-PROJECT-16K08519, KAKENHI-PROJECT-26460396
  • [Journal Article] State-dependent diffusion of actin-depolymerizing factor/cofilin underlies the enlargement and shrinkage of dendritic spines.2016

    • Author(s)
      Noguchi, J., Hayama, T., Watanabe, S., Ucar, H., Yagishita, S., Takahashi, N. & Kasai, H.
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 32897-32897

    • DOI

      10.1038/srep32897

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26430005, KAKENHI-PROJECT-26460290
  • [Journal Article] Design and Synthesis of a 4-Nitrobromobenzene Derivative Bearing an Ethylene Glycol Tetraacetic Acid Unit for a New Generation of Caged Calcium Compounds with Two-Photon Absorption Properties in the Near-IR Region and Their Application in Vivo2016

    • Author(s)
      Satish Jakkampudi, Manabu Abe, Naomitsu Komori Ryukichi Takagi, Ko Furukawa, Claudine Katan, Wakako Sawada, Noriko Takahashi, and Haruo Kasai
    • Journal Title

      ACS Omega

      Volume: 1 Issue: 2 Pages: 193-201

    • DOI

      10.1021/acsomega.6b00119

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-24109008, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26410121, KAKENHI-PROJECT-26460290
  • [Journal Article] Design and synthesis of a new chromophore, 2-(4-nitrophenyl)benzofuran, for two-photon uncaging using near-IR light2016

    • Author(s)
      Komori, N.; Jakkampudi, S.; Motoishi, R.; Abe, M.; Kamada, K.; Furukawa, K.; Katan, C.; Sawada, W.; Takahashi, N.; Kasai, H.; Xue, B.; Kobayashi, T.
    • Journal Title

      Chemical Communications

      Volume: 52 Issue: 2 Pages: 331-334

    • DOI

      10.1039/c5cc07664a

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H00966, KAKENHI-PLANNED-24109008, KAKENHI-PROJECT-26221001, KAKENHI-PLANNED-26107004, KAKENHI-PROJECT-26460290
  • [Journal Article] Labelling and optical erasure of synaptic memory traces in the motor cortex.2015

    • Author(s)
      Hayashi-Takagi A, Yagishita S, Nakamura M, Shirai F, Wu YI, Loshbaugh AL, Kuhlman B, Hahn KM, Kasai H
    • Journal Title

      Nature

      Volume: 525 Issue: 7569 Pages: 333-338

    • DOI

      10.1038/nature15257

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-24116001, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26293260, KAKENHI-PLANNED-24116003
  • [Journal Article] Two-photon fluorescence lifetime imaging of primed SNARE complexes in presynaptic terminals and β cells.2015

    • Author(s)
      Takahashi N#, Sawada W#, Noguchi J#, Watanabe S#, Ucar H, Hayashi-Takagi A, Yagishita S, Ohno M, Tokumaru H & Kasai H. (#Equally contributed).
    • Journal Title

      Nature Communications

      Volume: 6 Issue: 1 Pages: 8531-8531

    • DOI

      10.1038/ncomms9531

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430005, KAKENHI-PROJECT-26460290, KAKENHI-PUBLICLY-26111706, KAKENHI-ORGANIZER-24116001, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26293260
  • [Journal Article] Caged Glutamates with π-Extended 1, 2-Dihydronaphthalene Chromophore : Design, Synthesis, Two-Photon Absorption Property, and Photochemical Reactivity2014

    • Author(s)
      Boinapally, S., Huang, B., Abe, M., Katan, C., Noguchi, J., Watanabe, S., Kasai, H., Xue, B. & Kobayashi, T.
    • Journal Title

      Opt Express

      Volume: 22 Issue: 17 Pages: 7822-30

    • DOI

      10.1021/jo501425p

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-PUBLICLY-26111706, KAKENHI-PROJECT-26250004, KAKENHI-PROJECT-26430005
  • [Journal Article] Lab-on-a-brain: Implantable micro-optical fluidic devices for neural cell analysis in vivo.2014

    • Author(s)
      Takehara, H. *, Nagaoka, A. *, Noguchi, J., Akagi, T., Kasai, H. & Ichiki, T.
    • Journal Title

      Scientific Report

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26250004
  • [Journal Article] Sub-diffraction resolution pump-probe microscopy with shot-noise limited sensitivity using laser diodes2014

    • Author(s)
      Miyazaki, J., Tsurui, H., Hayashi-Takagi, A., Kasai, H. & Kobayashi, T.
    • Journal Title

      Opt Express

      Volume: 22 Issue: 8 Pages: 9024-32

    • DOI

      10.1364/oe.22.009024

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116003, KAKENHI-PROJECT-24740261, KAKENHI-PROJECT-25330349, KAKENHI-PROJECT-26250004, KAKENHI-PROJECT-26293260
  • [Journal Article] PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence2014

    • Author(s)
      Hayashi-Takagi, A., Araki, Y., Nakamura, M., Vollrath, B., Duron, S.G., Yan, Z., Kasai, H., Huganir, R.L., Campbell, D.A. & Sawa, A.
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A.

      Volume: 111 Issue: 17 Pages: 6461-6

    • DOI

      10.1073/pnas.1321109111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116003, KAKENHI-PROJECT-26293260
  • [Journal Article] A critical time window for dopamine action on the structural plasticity of dendritic spines.2014

    • Author(s)
      Yagishita, S., Hayashi-Takagi, A., Suzaki, R. & Kasai, H.
    • Journal Title

      Science

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26250004
  • [Journal Article] Lab-on-a-brain : Implantable micro-optical fluidic devices for neural cell analysis in vivo2014

    • Author(s)
      Takehara, H.*, Nagaoka, A.*, Noguchi, J., Akagi, T., Kasai, H. & Ichiki, T.
    • Journal Title

      Scientific Report

      Volume: 4 Issue: 1 Pages: 6721-6721

    • DOI

      10.1038/srep06721

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-PUBLICLY-26111706, KAKENHI-PROJECT-26430005
  • [Journal Article] A critical time window for dopamine actions on the structural plasticity of dendritic spines.2014

    • Author(s)
      Yagishita, S., Hayashi-Takagi, A., Ellis-Davies, G.C.R., Urakubo, H., Ishii, S., & Kasai, H.
    • Journal Title

      Science

      Volume: 345 Issue: 6204 Pages: 1616-1620

    • DOI

      10.1126/science.1255514

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22115012, KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116003, KAKENHI-PROJECT-26293260, KAKENHI-PROJECT-26540154
  • [Journal Article] PAK inhibitors rescue DISC1-deficit-triggered dendritic spine deterioration : novel therapeutic potential for schizophrenia.2014

    • Author(s)
      Hayashi-Takagi, A., Araki, Y., Nakamura, M., Vollrath, B., Duron, S. G., Yan, Z., Kasai, H., Huganir, R. L., Campbell, D. A., Sawa, A.
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] Evaluation of dialkylaminofluorene-based hemicyanine dyes for second harmonic generation imaging by the direct comparison approach.2013

    • Author(s)
      Nuriya, M, Momotake, A, Kimura, Y., Yasui, M., Kasai, H. & Arai, T.
    • Journal Title

      Bull. Chemical Soc. Jpn.

      Volume: 86 Issue: 10 Pages: 1190-1192

    • DOI

      10.1246/bcsj.20130094

    • NAID

      10031201275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-PROJECT-23350075, KAKENHI-PROJECT-23657106, KAKENHI-PROJECT-25620123
  • [Journal Article] Next-generation transgenic mice for optogenetic analysis of neural circuits.2013

    • Author(s)
      Asrican, B, Augustine, G. J., Berglund, K., Chen, S., Chow, N. Deisseroth, K., Feng, G., Gloss, B. Hira, R., Hoffman, C., Kasai, K., Katarya, M.
    • Journal Title

      Frontier in Neural Circuits

      Volume: 7 Pages: 1-10

    • DOI

      10.3389/fncir.2013.00160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-PLANNED-22115005, KAKENHI-PROJECT-23300148, KAKENHI-PROJECT-25893287
  • [Journal Article] Spatiolemporal dynamics of functional clusters of neurons in mouse motor corlex during a voluntary movement2013

    • Author(s)
      Hira R, Okubo F, Ozawa K, Isomura Y, KHamura K, Kano M, Kasai H, Matsuzaki M
    • Journal Title

      Journal of Neuroscience

      Volume: 33 Issue: 4 Pages: 1377-90

    • DOI

      10.1523/jneurosci.2550-12.2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J00136, KAKENHI-PROJECT-21000009, KAKENHI-PROJECT-21220006, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-22680031, KAKENHI-PROJECT-23650204, KAKENHI-PROJECT-24300143, KAKENHI-PUBLICLY-23115504, KAKENHI-PUBLICLY-24120715
  • [Journal Article] GABA promotes the competitive selection of dendritic spines by controlling local Ca2+ signaling. Nature Neurosci. 16:1409-1416.2013

    • Author(s)
      Hayama, T., Noguchi, J., Watanabe, S., Ellis-Davies, G. C. R., Hayashi, A., Takahashi, N., Matsuzaki, M. & Kasai, H.
    • Journal Title

      Nature Neurosci.

      Volume: 16 Issue: 10 Pages: 1409-1416

    • DOI

      10.1038/nn.3496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-PLANNED-22115005, KAKENHI-PROJECT-23300148, KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116003
  • [Journal Article] Implementation of tetra-poly (ethylene glycol) hydrogel with high mechanical strength into microfluidic device technology.2013

    • Author(s)
      Takehara, H., Nagaoka, A., Noguchi, J., Akagi, T., Sakai, T., Chung, U., Kasai, H. & Ichiki, T.
    • Journal Title

      Biomicrofluidics

      Volume: 7 Issue: 5 Pages: 1-9

    • DOI

      10.1063/1.4822033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] Polarity-dependent photophysical properties of hemicyanine dyes and their application in 2-photon microscopy biological imaging.2012

    • Author(s)
      Kimura, Y., Momotake, A., Takahashi, N., Kasai, H. & Arai, T.
    • Journal Title

      Chemistry Letters

      Volume: 41 Issue: 5 Pages: 528-530

    • DOI

      10.1246/cl.2012.528

    • NAID

      10030619751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-PROJECT-22750143, KAKENHI-PROJECT-23350075
  • [Journal Article] Distinct initial SNARE configurations underlying the diversity of exocytosis.2012

    • Author(s)
      Kasai, H., Takahashi, N. & Tokumaru, H.
    • Journal Title

      Physiol. Rev.

      Volume: 92 Issue: 4 Pages: 1915-1964

    • DOI

      10.1152/physrev.00007.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] A novel function of Noc2 in agonist-induced intracellular Ca2+ increase during zymogen-granule exocytosis in pancreatic acinar cells.2012

    • Author(s)
      Ogata, S., Miki, T., Seino, S., Tamai, S., Kasai, H. & Nemoto, T.
    • Journal Title

      PLoS ONE

      Volume: e37048 Issue: 5 Pages: 1-9

    • DOI

      10.1371/journal.pone.0037048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-PROJECT-22300131, KAKENHI-PROJECT-22590970, KAKENHI-PROJECT-24229007, KAKENHI-PLANNED-22113005
  • [Journal Article] In vivo two-photon uncaging of glutamate revealing the structure-function relationships of dendritic spines in the neocortex of adult mice2011

    • Author(s)
      Noguchi, J., Nagaoka, A., Watanabe, S., Ellis-Davies, G.C.R., Kitamura, K., Kano, M., Matsuzaki, M. & Kasai H.
    • Journal Title

      J.Physiol.

      Volume: 589 Issue: 10 Pages: 2447

    • DOI

      10.1113/jphysiol.2011.207100

    • URL

      https://pure.teikyo.jp/en/publications/6bd20e90-3fe3-4d5d-8c39-c671ea0eeda1

    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-PROJECT-21220006, KAKENHI-PROJECT-21500367, KAKENHI-PLANNED-22115005, KAKENHI-PROJECT-22650083, KAKENHI-PROJECT-22680031, KAKENHI-PUBLICLY-23115504, KAKENHI-PROJECT-23300148, KAKENHI-PROJECT-23650204
  • [Journal Article] Two-Photon Uncaging Microscopy.2011

    • Author(s)
      Matsuzaki, M. & Kasai, H.
    • Journal Title

      Cold Spring Harbor protocols

      Volume: 2011 Issue: 5 Pages: 555-561

    • DOI

      10.1101/pdb.prot5620

    • Data Source
      KAKENHI-PROJECT-21000009, KAKENHI-PLANNED-22115005, KAKENHI-PROJECT-23300148
  • [Journal Article] Decreased in the number of dense core vesicles is responsible for the impaired secretion if insulin in IA-2 and IA-2ss null mice2011

    • Author(s)
      Cai, T., Hirai, H., Zhang, G, Zhang, M., Takahashi, N., Kasai, H., Satin, L.S., Leapman, R.D., Notkins, A.L.
    • Journal Title

      Diabetologia

      Volume: 54 Pages: 2347-2357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] Spatial distributions of GABA receptors and local inhibition of Ca^<2+> transients studied with GABA uncaging in the dendrites of CA1 pyramidal neurons2011

    • Author(s)
      Yuya Kanemoto, Masanori Matsuzaki, Susumu Morita, Tatsuya Hayama, Jun Noguchi, Naoko Senda, Atsuya Momotake, Tatsuo Arai, Haruo Kasai
    • Journal Title

      PLoS One

      Volume: 6 Issue: 7 Pages: e22652-e22652

    • DOI

      10.1371/journal.pone.0022652

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J05575, KAKENHI-PROJECT-21000009, KAKENHI-PROJECT-21500367, KAKENHI-PLANNED-22115005, KAKENHI-PROJECT-22750143, KAKENHI-PROJECT-23300148, KAKENHI-PROJECT-23350075
  • [Journal Article] Simultaneous two-photon activation of presynaptic cells and calcium imaging in postsynaptic dendritic spines2011

    • Author(s)
      Matsuzaki, M., Ellis-Davies, G.C.R., Kanemoto, Y., Kasai, H.
    • Journal Title

      Neural Systems and Circuits

      Volume: 1 Pages: 2-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] Two-color, two-photon uncaging of glutamate and GABA.2010

    • Author(s)
      Kantevari, S. *, Matsuzaki, M. *, Kanemoto, Y., Kasai, H. CA, Ellis-DaviesG.C.R. CA
    • Journal Title

      Nature Methods 7

      Pages: 123-125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Class IA phosphoinositide 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms2010

    • Author(s)
      Kaneko, K., Ueki, K., Takahashi, N., Hashimoto, S., Okamoto, M., Awazawa, M., Okazaki, Y., Ohsugi, M., Inabe, K., Umehafa T., Yoshida M., Kakei M., Kitamura, T., Luo, J., Kulkarni, R.N., Kahn, C.R., Kasai, H., Cantley, L.C., Kadowaki, T.
    • Journal Title

      Cell Metabolism

      Volume: 12 Pages: 619-632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] Exocytosis in islet beta-cells.2010

    • Author(s)
      Kasai, H., Hatakeyama, H., Ohno, M., Takahashi, N.
    • Journal Title

      Advances in Experimental Medicine and Biology 654

      Pages: 3-336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] 1-Acyl-5-methoxy-8-nitro-1,2-dihydroquinoline : A biologically useful photolabile precursor of carboxylic acids2010

    • Author(s)
      Obi, N., Momotake, A., Kanemoto, Y., Matsuzaki, M, Kasai, H., Arai, T.
    • Journal Title

      Tetrahedron letters

      Volume: 51 Pages: 1642-1657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] Structural dynamics of dendritic spines in memory and cognition.2010

    • Author(s)
      Kasai, H., Fukuda, M, Watanabe, S., Hayashi-Takagi, A., Noguchi, J.
    • Journal Title

      Trends Neurosci 33

      Pages: 121-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Structural dynamics of dendritic spines in memory and cognition2010

    • Author(s)
      Kasai, H., et al.
    • Journal Title

      Trends in Neurosciences 33

      Pages: 121-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] SNARE conformational changes that prepare vesicles for exocytosis2010

    • Author(s)
      Takahashi, N., Hatakeyama, H., Okado, H., Noguchi, J.Ohno, M., Kasai, H.
    • Journal Title

      Cell Metabolism

      Volume: 12 Pages: 19-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] Two photon uncaging of γ-aminobutyric acid probes on neurons in intact brain tissue.2010

    • Author(s)
      Matsuzaki, M. Hayama, T., Kasai, H., Ellis-Davies, G.C. R
    • Journal Title

      Nature Chemical Biology 6

      Pages: 255-257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Exocytosis in islet beta-cells2010

    • Author(s)
      Kasai, H., et al.
    • Journal Title

      Advances in Experimental Medicine and Biology 654

      Pages: 303-336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] 1-Acyl-5-methoxy-8-nitro-1, 2-dihydroquinoline: A biologically useful photolabile precursor of carboxylic acids.2010

    • Author(s)
      Obi, N., Momotake, A., Kanemoto, Y., Matsuzaki, M, Kasai, H., Arai, T.
    • Journal Title

      Tetrahedron letters 51

      Pages: 1642-1657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] SNARE conformational changes that prepare vesicles for exocytosis.2010

    • Author(s)
      Takahashi, N., Hatakeyama, H., Okado, H., Noguchi, J. Ohno, M., Kasai, H.
    • Journal Title

      Cell Metabolism (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Learning rules and persistence of dendritic spines2010

    • Author(s)
      Kasai, H., Hayama, T., Ishikawa, M., Watanabe, S., Yagishita, S.
    • Journal Title

      Eur.J.Neurosci.

      Volume: 32 Pages: 241-249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Journal Article] Generation, elimination and weight fluctuations of synapses in the cerebral cortex.2009

    • Author(s)
      Morita, S., Yasumatsu, N. Noguchi, J., Kasai, H.
    • Journal Title

      Communicative and Integrative Biology 2

      Pages: 1-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Transcranial optogenetic stimulation for functional mapping of the motor cortex.2009

    • Author(s)
      Hira, R., Honkura, N., Noguchi, J., Maruyama, Y., Augustine, G.J., Kasai, H., Matsuzaki, M.
    • Journal Title

      J. Neurosci. Methods 179

      Pages: 258-263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] 2光子励起画像法によるインスリン開口放出の解析2009

    • Author(s)
      高橋倫子、大野光代、河西春郎
    • Journal Title

      Diabetes Journal 37

      Pages: 37-41

    • Data Source
      KAKENHI-PROJECT-19590204
  • [Journal Article] cAMPによるインスリン分泌増強機構2008

    • Author(s)
      高橋倫子、河西春郎
    • Journal Title

      新時代の糖尿病学(1) 66

      Pages: 164-168

    • Data Source
      KAKENHI-PROJECT-19590204
  • [Journal Article] The subspine organization of actin fibers regulates the structure and plasticity of dendritic spines.2008

    • Author(s)
      Honkura, N., Matsuzaki, M., Noguchi, J., Ellis-Davies, G.C.R., Kasai, H.
    • Journal Title

      Neuron 57

      Pages: 719-729

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines.2008

    • Author(s)
      Tanaka, J., Horiike, Y., Matsuzaki, M., Miyazaki, T., Ellis-Davies, GCR, Kasai, H.
    • Journal Title

      Science 319

      Pages: 1683-1687

    • NAID

      130007039544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Three-dimensional 5 mapping of unitary synaptic connections by two-photon macro photolysis of caged glutamate.2008

    • Author(s)
      Matsuzaki., M., Ellis-Davies, G.C.R., Kasai, H.
    • Journal Title

      J. Neurophysiol. 99

      Pages: 1535-1544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Principles of long-term dynamics of dendritic spines.2008

    • Author(s)
      Yasumatsu, N., Matsuzaki, M., Miyazaki, T., Noguchi, J., Kasai, H.
    • Journal Title

      J. Neurosci. 28

      Pages: 13592-13608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Two cAMP-dependent pathways differentially regulate exocytosis of large dense-core and small vesicles in b-cells2007

    • Author(s)
      Hatakeyama H., Takahashi N., Kishimoto T., Nemoto T., Kasai H.
    • Journal Title

      J. Physiol. Vol 582

      Pages: 1087-1098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Journal Article] Activation and high-speed mapping of brain circuitry using photostimulation in Channelrhodopsin-2 transgenic mice.2007

    • Author(s)
      Wang, H. *, Peca, J. *, Matsusaki, M. *, Matsuzaki, K., Noguchi, J., Qiu, L., Wang, D., Zhang, F., Boyden, E., Deisseroth, K., Kasai, H., Hall, W.C., Feng, G., Augustine, G.J.
    • Journal Title

      PNAS 104

      Pages: 8143-8148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] CDNI-Glu: an improved caged glutamate for expeditious ultraviolet and 2-photon photolysis in brain slices.2007

    • Author(s)
      Ellis-Davies, G.C.R., Matsuzaki, M., Paukert, M., Kasai, H., Bergles, D.E.
    • Journal Title

      J. Neurosci. 27

      Pages: 6601-6604

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Exocytic Process Analyzed with Two-photon Excitation Imaging in Endocrine Pancreas2007

    • Author(s)
      Takahashi N., Kasai H.
    • Journal Title

      Endocrine J. Vol 54

      Pages: 337-346

    • NAID

      130004770028

    • Data Source
      KAKENHI-PROJECT-19590204
  • [Journal Article] Two cAMP-dependent pathways differentially regulate exocytosis of large dense-core and small vesicles in mouse beta-cells.2007

    • Author(s)
      Hatakeyama H, Takahashi N, Kishimoto T, Nemoto T & Kasai H
    • Journal Title

      Journal of Physiology 582

      Pages: 1087-1098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Journal Article] Exocytic process analyzed with two-photon excitation imaging in endocrine pancreas.2007

    • Author(s)
      Takahashi N and Kasai H
    • Journal Title

      Endocrine Journal 54

      Pages: 337-347

    • NAID

      130004770028

    • Data Source
      KAKENHI-PROJECT-19590204
  • [Journal Article] Two cAMP-dependent pathways differentially regulate large-dense core and small vesicles in mouse beta cells.2007

    • Author(s)
      Hatakeyama, H., Takahashi, N., Kishimoto, T., Nemoto, T., Kasai, H.
    • Journal Title

      J. Physiol. 582

      Pages: 1087-1098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Exocytic process analyzed with two-photon excitation imaging in endocrine pancreas.2007

    • Author(s)
      Takahashi, N., Kasai, H.
    • Journal Title

      Endocrine J. 54

      Pages: 337-347

    • NAID

      130004770028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Rapid glucose sensing by protein kinase A for insulin exocytosis in mouse pancreatic islets.2006

    • Author(s)
      Hatakeyama, H., Kishimoto, T., Nemoto, T., Kasai, H., Takahashi, N.
    • Journal Title

      J. Physiol. 570

      Pages: 271-282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Vacuolar sequential exocytosis of large dense-core vesicles in adrenal medulla.2006

    • Author(s)
      Kishimoto, T., Kimura, R., Liu, T. -T., Nemoto, T., Takahashi, N., Kasai, H.
    • Journal Title

      EMBO J. 25

      Pages: 673-682

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Two-photon excitation imaging of exocytosis and endpcytosis and determination of their spatial organization.2006

    • Author(s)
      Kasai, H.
    • Journal Title

      Adv. Drug Delivery Rev. 58

      Pages: 850-877

    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Two-photon excitation imaging of exocytosis and endocytosis and determination of their spatial organization.2006

    • Author(s)
      Kasai, H., Kishimoto, T. Nemoto, T. Hatakeyama, H, Liu, T-T., Takahashi, N.
    • Journal Title

      Adv. Drug Delivery Rev. 58

      Pages: 850-877

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Spine-neck geometry determines NMDA receptor-dependent Ca^2+ signaling in dendrites.2005

    • Author(s)
      Noguchi, J., Matsuzaki, M., Ellis-Davies, G.C.R., Kasai, H.
    • Journal Title

      Neuron 46

      Pages: 609-622

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] A new quantitative (two-photon extracellular polar-tracer imaging-based quantification (TEPIQ)) analysis for diameters of exocytic vesicles and its application to pancreatic islets.2005

    • Author(s)
      Kasai, H., Hatakeyama, H., Kishimoto, T., Liu, T. -T., Nemoto, T., Takahashi, N.
    • Journal Title

      J. Physiol. 568

      Pages: 891-903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Number and Density of AMPA Receptors in Single Synapses in Immature Cerebellum.2005

    • Author(s)
      Tanaka, J., Matsuzaki, M., Tarusawa, E., Momiyama, A., Molnar, E., Kasai, H., Shigemoto, R.
    • Journal Title

      J. Neurosci. 25

      Pages: 799-807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Rapid Ca^<2+>-dependent increase in oxygen consumption by mitochondria in single mammalian central neurons2005

    • Author(s)
      Y.Hayakawa, T.Nemoto, M.Iino, H.Kasai
    • Journal Title

      Cell Ca. (In press)

    • Data Source
      KAKENHI-PROJECT-12144209
  • [Journal Article] Two-photon microscopic analysis of acetylcholine-induced mucus secretion in guinea pig nasal glands2005

    • Author(s)
      A.Oshima, T.Kojima, K.Dejima, Y.Hisa, H.Kasai, T.Nemoto
    • Journal Title

      Cell Ca. (In press)

    • Data Source
      KAKENHI-PROJECT-12144209
  • [Journal Article] Two-photon microscopic analysis of acetylcholine-induced mucus secretion in guinea pig nasal glands.2005

    • Author(s)
      Oshima, A., Kojima, T., Dejima, K., Hisa, I., Kasai, H., Nemoto, T.
    • Journal Title

      Cell Calcium 37

      Pages: 349-357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Rapid Ca2+-dependent increase in oxygen consumption by mitochondria in single mammalian central neurons.2005

    • Author(s)
      Hayakawa, Y., Nemoto, T., Iino, M., Kasai, H.
    • Journal Title

      Cell Calcium 37

      Pages: 359-370

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] A new quantitative (TEPIQ) analysis for diameters of exocytic vesicles and its application to pancreatic islets2005

    • Author(s)
      Kasai H
    • Journal Title

      J Physiol 568

      Pages: 891-903

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144209
  • [Journal Article] Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation2005

    • Author(s)
      Kasai, K.
    • Journal Title

      J.Clin.Invest. 115

      Pages: 388-396

    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Exocytosis and endocytosis of small vesicle in PC12 cells studied with TEPIQ (two-photon extracellular polar-tracer imaging-based quantification) analysis.2005

    • Author(s)
      Liu, T. -T., Kishimoto, T., Hatakeyama, H., Nemoto, T., Takahashi, N., Kasai, H.
    • Journal Title

      J. Physiol. 568

      Pages: 917-929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] A new quantitative (two-photon extracellular polar-tracer imaging-based quantification (TEPIQ)) analysis for diameters of exocytic vesicles and its application to pancreatic islets.2005

    • Author(s)
      Kasai, H.
    • Journal Title

      J.Physiol. 568

      Pages: 891-903

    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Sequential compound exocytosis of large dense-core vesicles in PC12 cells studied with TEPIQ (two-photon extracellular polar-tracer imaging-based quantification) analysis.2005

    • Author(s)
      Kishimoto, T., Liu, T. -T., Hatakeyama, H., Nemoto, T., Takahashi, N., Kasai, H.
    • Journal Title

      J. Physiol. 568

      Pages: 905-915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] A new quantitative (TEPIQ) analysis for estimating diameters of exocytic vesicles and its application to pancreatic islets2005

    • Author(s)
      Kasai H.
    • Journal Title

      J Physiol 568

      Pages: 891-903

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144209
  • [Journal Article] Two-photon uncaging microscopy2004

    • Author(s)
      Kasai, H., Matsuzaki, M., Ellis-Davies, G.C.R.
    • Journal Title

      In "Imaging in Neuroscience and Development, " CSH Lab (Press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Stabilization of exocytosis by dynamic F-actin coating of zymogen granules in pancreatic acini.2004

    • Author(s)
      Nemoto, T., Kojima, T., Oshima, A., Bito, H., Kasai, H.
    • Journal Title

      J. Biol. Chem 279

      Pages: 37544-37550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Stabilization of exocytosis by dynamic F-actin coating of Zymogen granules in pancreatic acini2004

    • Author(s)
      T.Nemoto, T.Kojima, A.Oshima, H.Bito, H.Kasai
    • Journal Title

      J.Biol.Chem. 279

      Pages: 37544-37550

    • Data Source
      KAKENHI-PROJECT-12144209
  • [Journal Article] Structural basis of long-term potentiation in single dendritic spines.2004

    • Author(s)
      Matsuzaki, M., Honkura, N., Ellis-Davies, G.C.R., Kasai, H.
    • Journal Title

      Nature 429

      Pages: 761-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Journal Article] Structure-stability-function relationships of dendritic spines2003

    • Author(s)
      Kasai, H.
    • Journal Title

      Trends Neurosci. 26

      Pages: 360-368

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144209
  • [Journal Article] Fast and cAMP-sensitive mode of Ca^<2+>-dependent exocytosis in pancreatic β cells2002

    • Author(s)
      Kasai, H.
    • Journal Title

      Diabetes 51 S1

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144209
  • [Patent] スパイン増強用タンパク質の発現コンストラクト、形質転換細胞、トランスジェニック非ヒト動物、精神障害、認知機能障害、睡眠障害、若しくは記憶障害の治療または予防用薬剤、及びスパイン増強方法2023

    • Inventor(s)
      澤田健、河西春郎、有馬知輝、柳下祥、岡崎斉
    • Industrial Property Rights Holder
      澤田健、河西春郎、有馬知輝、柳下祥、岡崎斉
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Patent] 走査型顕微鏡及び標本画像取得方法2007

    • Inventor(s)
      河西春郎、松崎政紀、服部敏征、松川康成、上野牧男、中田竜男
    • Industrial Property Rights Holder
      河西春郎、松崎政紀、オリンパス株式会社
    • Industrial Property Number
      2007-285938
    • Filing Date
      2007-01-12
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Patent] 脂質膜小胞のサイズ決定方法、脂質膜小胞の存否の判定方法2005

    • Inventor(s)
      岸本拓哉、河西春郎
    • Industrial Property Rights Holder
      科学技術振興機構
    • Industrial Property Number
      2005-107593
    • Filing Date
      2005-07-07
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Patent] 多光子励起蛍光寿命画像化システム2000

    • Inventor(s)
      根本 知己, 河西 春郎
    • Industrial Property Rights Holder
      独立行政法人科学技術振興機構
    • Industrial Property Number
      2000-226758
    • Filing Date
      2000-07-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144209
  • [Presentation] Mechanical brain: The force of synapses on the dendritic spines for memory and cognitive function2024

    • Author(s)
      Haruo Kasai
    • Organizer
      Special lecture, 101th Annual Meeting of Physiological Society of Japan (Fukuoka, Japan).
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] The force of dendritic-spine enlargement facilitating presynaptic exocytosis2023

    • Author(s)
      Haruo Kasai
    • Organizer
      Excitatory Synapses and Brain Function Gordon Research Conference (Les Diablerets, Switzerland).
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] 大脳スパインシナプスの運動と記憶・精神疾患2023

    • Author(s)
      河西春郎
    • Organizer
      宮崎大学セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] Mechanical brain: The force of dendritic-spine synapses for memory and cognition2023

    • Author(s)
      Haruo Kasai
    • Organizer
      The Laboratory of Molecular Biology seminar series(Cambridge, UK).
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] The force of dendritic-spine synapses in mental functions and disorders2023

    • Author(s)
      163.Haruo Kasai
    • Organizer
      IRCN- iPlasticity International Symposium
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] Mechanical synaptic transmission: A frontier in neuroscience2023

    • Author(s)
      Haruo Kasai
    • Organizer
      The Augustine Symposium (NTU, Singapore).
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] シナプスの力学カップリングを担う軸索終末機構2022

    • Author(s)
      162.河西春郎
    • Organizer
      革新的先端研究開発支援事業(AMED-CREST/PRIME)シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] Mechanical actions of brain spine synapses underlying learning and memory2022

    • Author(s)
      Kasai, H.
    • Organizer
      Nature Virtual Conference (Zoom)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] Mechanical actions of dendritic-spine enlargement and the discovery of the PREST mechanism in the presynaptic terminals in the CNS.2022

    • Author(s)
      Ucar, H., Watanabe, S., Noguchi, J., Yagishita, S., Takahashi, N., Kasai, H.
    • Organizer
      JNS
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] 大脳スパインシナプスの運動と機能・精神疾患2022

    • Author(s)
      河西春郎
    • Organizer
      FUJITAブレインサイエンスセミナー(藤田医科大学, Zoom)
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] The force of dendritic-spine enlargement facilitating presynaptic exocytosis.2022

    • Author(s)
      H. Kasai
    • Organizer
      The International Symposium on Development and Plasticity of Neural Systems, WPI-ASHBi
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] Mechanical interactions of dendritic-spine synapses.2022

    • Author(s)
      H. Kasai
    • Organizer
      JST-CREST "Opt Bio" / IIIS Joint Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] 運動するシナプスの探求は続く2022

    • Author(s)
      河西春郎
    • Organizer
      東京大学大学院医学系研究科退官記念最終講義(公開)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] 大脳スパインシナプスと記憶・精神疾患2022

    • Author(s)
      河西春郎
    • Organizer
      東京大学大学院薬学系研究科大学院講義「疾患生物学特論」
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] Spine dynamics, mental disorders and artificial intelligence2021

    • Author(s)
      H. Kasai
    • Organizer
      Science Salon of IRCN (Zoom)
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] Dopamine actions on the dendritic spines for reward and aversive learning in the nucleus accumbens2020

    • Author(s)
      Takeshi Sawada & Haruo Kasai
    • Organizer
      UT Bioscience, University of Tokyo
    • Data Source
      KAKENHI-PROJECT-20H00480
  • [Presentation] Intrinsic dynamics of dendritic spines.2020

    • Author(s)
      Okazaki, H. & Kasai, H.
    • Organizer
      Annual meeting of Japanese Neuroscience Society 2020
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] Intrinsic dynamics of dendritic spine2020

    • Author(s)
      Hitoshi Okazaki & Haruo Kasai
    • Organizer
      Japanese Society of Neuroscience 2020
    • Data Source
      KAKENHI-PROJECT-20H00480
  • [Presentation] Potentiation of presynaptic functions by mechanosensing the spine enlargement in rat hippocampus.2020

    • Author(s)
      Ucar, H., Watanabe, S., Noguchi, J., Yagishita, S., , Morimoto, Y., Takahashi, N., Kasai, H.
    • Organizer
      FENS (Glasgow online).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05685
  • [Presentation] Dopamine receptors, synaptic plasticity and psychiatric disorders2019

    • Author(s)
      H. Kasai
    • Organizer
      Japan-UK Neuroscience Symposium 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Mechanical forces of spine enlargement detected by presynaptic FRET/FLIM imaging2019

    • Author(s)
      H. Kasai
    • Organizer
      Federation of the Asian and Oceanian Physiolgocial Societies (FAOPS), Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Bidirectional tuning of behavioral conditioning and synaptic plasticity by dopamine in the nucleus accumbens, Japan-Canadian Joint Symposium2018

    • Author(s)
      H. Kasai, Y. Iino, R. Nakazato, K. Yamaguchi, T. Sawada, S. Yagishita
    • Organizer
      Japanese Society of Neuroscience 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Dopamine actions on the dendritic spines for reward and aversive learning in the nucleus accumbens2018

    • Author(s)
      H. Kasai
    • Organizer
      World Congress of Pharmacological Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Synaptic optogenetics for memory structures2018

    • Author(s)
      H. Kasai
    • Organizer
      Mini-Symposium, Japanese Society of Neuroscience 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Synaptic optogenetics for memory structures.2018

    • Author(s)
      H. Kasai
    • Organizer
      World Congress of Pharmacological Sciences 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Dopamine actions on the dendritic spines and conditioned behaviors2017

    • Author(s)
      Haruo Kasai
    • Organizer
      The 48th NIPS International Symposium on “Neural circuitry and plasticity underlying brain functions”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Dopamine actions on the structural plasticity of dendritic spines2017

    • Author(s)
      Haruo Kasai
    • Organizer
      Gordon Research Conference on Synaptic Transmission
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Identification of the synapses involved in memory formation2017

    • Author(s)
      Haruo Kasai
    • Organizer
      The brain Conferences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Dopamine actions on the dendritic spines of medium spiny neurons in the nucleus accumbens for classical conditioning2017

    • Author(s)
      Haruo Kasai, Yusuke Iino, Yoshitomo Maeda, Ryo Nakazato, Sho Yagishita
    • Organizer
      新学術国際シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] 2光子励起蛍光寿命画像法で解析した開口放出部位におけるSNAP25の分子構造、第94回日本生理学会2017

    • Author(s)
      高橋、渡辺、澤田、河西
    • Organizer
      第94回日本生理学会
    • Place of Presentation
      アクトシティ浜松(静岡県浜松市)
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Plasticity and fluctuations of dendritic spines; synaptic bases of memory and mental disorders2017

    • Author(s)
      Haruo Kasai
    • Organizer
      Neurosci 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Spine synapses shaping memory and behavior, Lecture, Nanyang Technical University2016

    • Author(s)
      Haruo Kasai
    • Organizer
      Lecture, Nanyang Technical University
    • Place of Presentation
      Nanyang Drive, Singapore
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] 2光子励起蛍光寿命画像法を用いたSNARE複合化の解析2016

    • Author(s)
      高橋 倫子、澤田 和可子、野口 潤、ハサン ウチャル、渡辺 惠、河西 春郎
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-07-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-26430005
  • [Presentation] Structural Plasticity of Dendritic Spines in NAc for Reinforcement Learning2016

    • Author(s)
      Haruo Kasai
    • Organizer
      Gordon Conference
    • Place of Presentation
      Ventura, CA, USA
    • Year and Date
      2016-03-03
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Rapid regulations of spine plasticity by dopamine in the D1 and D2 projection neurons in the nucleus accumbens. Cold Spring Harbor Asia Conference2016

    • Author(s)
      Haruo Kasai, Sho Yagishita, Yusuke Iino, Yosuke Nakazato, Yoshitomo Maeda
    • Organizer
      Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou, China
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Plasticity and fluctuations of dendritic spines studied with synaptic optogenetics.2016

    • Author(s)
      Haruo Kasai
    • Organizer
      iCeMS, MRC and AMED workshop
    • Place of Presentation
      Cambridge, UK
    • Year and Date
      2016-03-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Synaptic optogenetics2016

    • Author(s)
      Haruo Kasai
    • Organizer
      Neocortical Organization Ⅲ
    • Place of Presentation
      東京大学小柴ホール(東京都文京区)
    • Year and Date
      2016-02-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] FRET-FLIM measurement with a trans-SNARE-probe detecting the mechanical force from dendritic spine to pre-synaptic bouton.2016

    • Author(s)
      ハサン ウチャル、渡辺 惠、野口 潤、高橋 倫子、澤田 和可子、栁下 祥、河西 春郎
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-07-22
    • Data Source
      KAKENHI-PROJECT-26430005
  • [Presentation] Synaptic optogenetics2016

    • Author(s)
      Haruo Kasai
    • Organizer
      Neocortical Organization Ⅲ
    • Place of Presentation
      東京大学小柴ホール(東京都,文京区)
    • Year and Date
      2016-02-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Dendritic spines shaping memory and behaviors2016

    • Author(s)
      Haruo Kasai
    • Organizer
      Special Lecture, Society for Neuroscience
    • Place of Presentation
      San Diego, CA, USA
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Structural Plasticity of Dendritic Spines in NAc for Reinforcement Learning2016

    • Author(s)
      Haruo Kasai
    • Organizer
      Gordon Conference
    • Place of Presentation
      Ventural, CA, USA
    • Year and Date
      2016-03-03
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Plasticity and fluctuations of dendritic spines in mice models of autism and schizophrenia.2016

    • Author(s)
      Haruo Kasai
    • Organizer
      Symposium in JNS meeting 2016
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] 大脳シナプスの生理と精神神経疾患2015

    • Author(s)
      河西春郎
    • Organizer
      青森ドーパミン研究会
    • Place of Presentation
      ホテルJALシティ青森(青森県,青森市)
    • Year and Date
      2015-11-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] 大脳シナプスの生理と精神神経疾患2015

    • Author(s)
      河西春郎
    • Organizer
      青森ドーパミン研究会
    • Place of Presentation
      ホテルJALシティ青森(青森県青森市)
    • Year and Date
      2015-11-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221001
  • [Presentation] Imaging and optogenetics of dendritic spines2015

    • Author(s)
      H. Kasai
    • Organizer
      BSI seminar series
    • Place of Presentation
      理化学研究所(埼玉県和光市)
    • Year and Date
      2015-02-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] A critical time window for dopamine actions on the dendritic spines in ventral striatum.2014

    • Author(s)
      H. Kasai & S. Yagishita
    • Organizer
      Max-Planck-Institute/U-Tokyo Symposium
    • Place of Presentation
      Florida, USA
    • Year and Date
      2014-05-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250004
  • [Presentation] The critical time window for dopamine actions on the structural plasticity of dendritic spines in the nucleus of accumbens2014

    • Author(s)
      H. Kasai & S. Yagishita
    • Organizer
      Symposium on“Emotional mechanisms”
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] ドーパミンによる側坐核スパイン形態可塑性の鋭い時間枠での調節とその分子機構2014

    • Author(s)
      柳下 祥、林(高木)朗子、渡邉恵、河西春郎
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島大学郡元キャンパス(鹿児島市)
    • Year and Date
      2014-03-16
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] 内分泌細胞と神経細胞におけるSNARE複合化の2光子FLIM解析.2014

    • Author(s)
      高橋倫子、澤田和可子、渡邉恵、大野光代、河西春郎
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島大学郡元キャンパス(鹿児島市)
    • Year and Date
      2014-03-18
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] The critical time window for dopamine actions on the structural plasticity of dendritic spines in the nucleus of accumbens2014

    • Author(s)
      H. Kasai & S. Yagishita
    • Organizer
      Neuro2014
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-26250004
  • [Presentation] シナプス可塑性記録のためのプレシナプスプローブの海馬培養スライスにおける使用2014

    • Author(s)
      野口潤、渡邊恵、高橋倫子、河西春郎
    • Organizer
      日本神経科学学会
    • Place of Presentation
      パシフィコ横浜(神奈川県、横浜市)
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-26430005
  • [Presentation] 半導体レーザーを用いた超解像誘導放出顕微鏡の開発と生体イメージングへの応用.2014

    • Author(s)
      宮崎 淳1,2, 鶴井 博理2,3, 林(高木)朗子4, 河西 春郎2,4, 小林 孝嘉1,2
    • Organizer
      第61回応用物理学会
    • Place of Presentation
      青山学院大学相模原キャンパス(相模原市)
    • Year and Date
      2014-03-18
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] シナプス前終末における開口放出関連蛋白SNAP25の構造と機能.2014

    • Author(s)
      澤田和可子、高橋倫子、渡邉恵、大野光代、河西春郎
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島大学郡元キャンパス(鹿児島市)
    • Year and Date
      2014-03-17
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Labeling and erasure of dendritic spines and motor learning with novel synaptic optogenetic probes in vivo2014

    • Author(s)
      H. Kasai & A. Hayashi
    • Organizer
      Janelia Conference for“Structure and function of synapses”
    • Place of Presentation
      Janelia Farm Research Campus(Ashburn, VA., USA)
    • Year and Date
      2014-04-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Presynaptic probe for reporting synaptic plasticity in hippocampal cultured slices2014

    • Author(s)
      J. Noguchi, Satoshi, W, Noriko, T. & H. Kasai
    • Organizer
      Neuro2014
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-26250004
  • [Presentation] ベータ細胞と神経終末の分泌分子機構の可視化解析2013

    • Author(s)
      河西春郎
    • Organizer
      朝日生命成人病研究所分泌セミナー
    • Place of Presentation
      ノボノルディスクファーマ(株)本社アピスカフェ(東京都千代田区)
    • Year and Date
      2013-10-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] 革新的的な脳計測・解析技術、「こころの健康社会の創造に向けて」2013

    • Author(s)
      H. Kasai
    • Organizer
      日本学術会議主催学術フォーラム
    • Place of Presentation
      東京大学鉄門記念講堂(東京都文京区)
    • Year and Date
      2013-09-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] A narrow time window for dopaminergic enhancement of spine structural plasticity in nucleus accumbens2013

    • Author(s)
      S. Yagishita, A. Hayashi-Takagi, S. Watanabe & H. Kasai
    • Organizer
      Neuro2013
    • Place of Presentation
      国立京都国際会館(京都市左京区)
    • Year and Date
      2013-06-21
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Structural plasticity of spine synapses in vitro and in vivo, Current trends and future directions of synaptic plasticity research2013

    • Author(s)
      H. Kasai
    • Organizer
      US/Japan joint workshop
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2013-07-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Imaging synaptic function and plasticity.2013

    • Author(s)
      H. Kasai
    • Organizer
      MRC-JST-British Embassy Tokyo Workshop : The use of next generation optical microscopy for neuroscience disease challenges
    • Place of Presentation
      在日本英国大使館(東京都千代田区)
    • Year and Date
      2013-09-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Structural plasticity of spine synapses studied with two-photon microscope.2012

    • Author(s)
      Haruo Kasai
    • Organizer
      International Symposium on in vivo microscopy
    • Place of Presentation
      Helsinki, Finland
    • Year and Date
      2012-05-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Chronic in vivo imaging of dendritic spines with a microfluidic device and open-dura surgery in the adult mouse cortex.2012

    • Author(s)
      A. Nagaoka, H. Takehara, J. Noguchi, T. Akagi, T. Ichiki & H. Kasai
    • Organizer
      42th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2012-10-14
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] The molecular basis of local synaptic competition between dendritic spines.2012

    • Author(s)
      T. Hayama, J. Noguchi, S. Watanabe, N. Takahashi, A. Hayashi-Takagi, G. C. R. Ellis-Davies, M. Matsuzaki & H. Kasai
    • Organizer
      42th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2012-10-13
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] 2光子蛍光寿命画像法による開口放出SNARE機構の研究2012

    • Author(s)
      河西春郎、高橋倫子、大野光代、澤田和可子
    • Organizer
      日本腎臓学会
    • Place of Presentation
      パシフィコ横浜会議センター(横浜市)
    • Year and Date
      2012-06-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Synaptic competition in the dendritic spines.2012

    • Author(s)
      Haruo Kasai, Tatsuya Hayama, Jun Noguchi, Satoshi Watanabe
    • Organizer
      Jacques-Monod Symposium in "Imaging neuronal functions: from molecules to circuits,"
    • Place of Presentation
      Roscoff, France
    • Year and Date
      2012-06-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Two-photon FRET/FLIM imaging of SNARE-dependent exocytosis. 42th Annual Meeting of Society for Neuroscience2012

    • Author(s)
      N. Takahashi, M. Ohno, S. Watanabe, W. Sawada & H. Kasai
    • Organizer
      42th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2012-10-15
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Statistical dynamics of synapses2011

    • Author(s)
      Haruo Kasai
    • Organizer
      System Neurobiology Spring School 2011
    • Place of Presentation
      コープイン京都(京都)(招待講演)
    • Year and Date
      2011-03-13
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] In vivo two-photon uncaging in the adult brain2010

    • Author(s)
      河西春郎
    • Organizer
      Janelia Conference for structural plasticity in mammalian brain
    • Place of Presentation
      ジャネリアファーム(米国)
    • Year and Date
      2010-03-23
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] 2光子顕微鏡の神経科学領域への応用2010

    • Author(s)
      河西春郎
    • Organizer
      京都大学大学院神経科学コース
    • Place of Presentation
      京都大学医学部(京都)(招待講演)
    • Year and Date
      2010-09-15
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] GABA dependence of locally competitive learning rules of dendritic spines revealed by two-color uncaging of glutamate and GABA2010

    • Author(s)
      Tatsuya Hayama, Yuya Kanemoto, Masanori Matsuzaki, Graham C.R.Ellis-Davies, Haruo Kasai
    • Organizer
      25^<th> Annual Meeting of Socienty for Neuroscience
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Optical stimulation illuminates synapses in the mammalian brain2010

    • Author(s)
      Haruo Kasai
    • Organizer
      新学術領域「分子行動学」シンポジウム
    • Place of Presentation
      東京大学小柴ホール(東京)(招待講演)
    • Year and Date
      2010-11-10
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] SNARE conformational changes that prepare vesicle for exocytosis2010

    • Author(s)
      Haruo Kasai
    • Organizer
      Biophysical Meeting
    • Place of Presentation
      北京国際会議場(中国)(招待講演)
    • Year and Date
      2010-10-11
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Imaging of synapses2010

    • Author(s)
      Haruo Kasai
    • Organizer
      BSI tutorial course 2010
    • Place of Presentation
      理研BSI(埼玉)(招待講演)
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] GABA dependence of glutamate-mediated shrinkage and enlimination of dendritic spines revealed with two-color glutamate and GABA2010

    • Author(s)
      Tatsuya Hayama, Yuya Kanemoto, Masanori Matsuzaki, Graham C.R.Ellis-Davies, Haruo Kasai
    • Organizer
      日本神経科学会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2010-09-04
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] インスリン分泌過程における膜融合関連蛋白質の構造変化2009

    • Author(s)
      高橋倫子、畠山裕康、大野光代、河西春郎
    • Organizer
      第52回日本糖尿病学会
    • Place of Presentation
      大阪(大阪国際会議場)
    • Year and Date
      2009-05-23
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Presentation] Protein synthesis and neurotrophin-dependent structural plasticity of dendritic spines.2009

    • Author(s)
      H. Kasai
    • Organizer
      Neurotrophic Factor Gordon Research Conference
    • Place of Presentation
      Rhode Island, USA
    • Year and Date
      2009-06-23
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] 分泌現象の2光子励起顕微鏡による解析2009

    • Author(s)
      河西春郎
    • Organizer
      解剖学会・生理学会連携シンポジウム
    • Place of Presentation
      岡山市、岡山理科大学
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Two-photon uncaging microscope to study cerebral synapses in vitro and in vivo2009

    • Author(s)
      河西春郎
    • Organizer
      第3回 Annual Nanobiotechnology Global Symposium
    • Place of Presentation
      ロサンゼルス(米国)
    • Year and Date
      2009-11-18
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Two-photon imaging of conformation changes in SNAP25 during insulin exocytosis from islet beta-cells, Symposium on exocytosis and neurons2009

    • Author(s)
      Kasai, H., Takahashi, N., Hatakeyama, H.
    • Organizer
      Japanese Cell Biology Meeting
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Patch-clamp, imaging and photostimulation.2009

    • Author(s)
      H. Kasai
    • Organizer
      Third Neurizons Conference
    • Place of Presentation
      Goettingen, Germany
    • Year and Date
      2009-05-15
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] インスリン分泌過程における膜融合関連蛋白質の構造変化2009

    • Author(s)
      高橋倫子、大野光代、河西春郎
    • Organizer
      第82回 日本内分泌学会
    • Place of Presentation
      群馬(群馬県民会館)
    • Year and Date
      2009-04-24
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Presentation] Patch-clamp, imaging and photostimulation2009

    • Author(s)
      河西春郎
    • Organizer
      Neurisons Conference 2010
    • Place of Presentation
      ゲッティンゲン(ドイツ)
    • Year and Date
      2009-05-15
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Two-photon imaging of brain cell dynamics2009

    • Author(s)
      H. Kasai
    • Organizer
      Two-photon uncaging in vitro and in vivo. EMBO Practival course in 6
    • Place of Presentation
      Zurich, Swiss
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Two-photon uncaging in vitro and in vivo2009

    • Author(s)
      河西春郎
    • Organizer
      EMBO Practical course in "Two-photon imaging of brain cell dynamics"
    • Place of Presentation
      Zurich(Swiss)
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] 新しい2光子刺激法の神経科学への応用2009

    • Author(s)
      河西春郎
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2009-09-16
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Protein dynamics during insulin exocytosis analyzed with two-photon imaging2009

    • Author(s)
      高橋倫子, 畠山裕康, 大野光代, 河西春郎
    • Organizer
      IUPS 2009(国際生理学会)
    • Place of Presentation
      Kyoto(Kyoto International Conference Center)
    • Year and Date
      2009-07-30
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Presentation] 2光子励起顕微鏡で見る大脳の運動するシナプス2008

    • Author(s)
      河西春郎
    • Organizer
      東京大学生命科学ネット
    • Place of Presentation
      文京区、東京大学安田講堂
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Long-term dynamics of dendritic spines studied with two-photon microscope : Possible relationships with schizophrenia.2008

    • Author(s)
      河西春郎
    • Organizer
      第31回日本神経科学会シンポジウム
    • Place of Presentation
      千代田区、東京国際フォーラム
    • Year and Date
      2008-07-11
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] 2光子顕微鏡による大脳シナプスの研究2008

    • Author(s)
      河西春郎
    • Organizer
      東京医科歯科大学大学院講義
    • Place of Presentation
      文京区、東京医科歯科大学
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] 大脳棘シナプスの統計動力学と神経回路機能2008

    • Author(s)
      河西春郎
    • Organizer
      生理研研究会
    • Place of Presentation
      岡崎市、自然科学研究機構生理学研究所
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Imaging of exocytosis and endocytosis with two-photon microscope.2008

    • Author(s)
      H. Kasai
    • Organizer
      International Meeting on Exocytosis
    • Place of Presentation
      Ljublijana, Slovenia
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] 大脳シナプスの2光子顕微鏡による研究2008

    • Author(s)
      河西春郎
    • Organizer
      名古屋大学医学系研究科大学院講義
    • Place of Presentation
      名古屋市、名古屋大学
    • Year and Date
      2008-12-22
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Synaptic plasticity in the Cerebral Cortex Studied with Two-Photon Microscope.2008

    • Author(s)
      Kasai, H.
    • Organizer
      BSI tutorial course
    • Place of Presentation
      和光市、理化学研究所
    • Year and Date
      2008-10-07
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] 2光子顕微鏡による大脳シナプスの研究2008

    • Author(s)
      河西春郎
    • Organizer
      大阪バイオサイエンス財団マンスリーレクチャー
    • Place of Presentation
      大阪府吹田市、大阪バイオサイエンス研究所
    • Year and Date
      2008-10-21
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Protein dynamics during insulin secretion analyzed with two-photon imaging2008

    • Author(s)
      高橋倫子, 畠山裕康, 大野光代, 河西春郎
    • Organizer
      NanoBio-Seoul 2008
    • Place of Presentation
      Seoul(Yonsei University)
    • Year and Date
      2008-10-30
    • Data Source
      KAKENHI-PROJECT-19590204
  • [Presentation] 大脳シナプスの2光子顕微鏡による研究2008

    • Author(s)
      河西春郎
    • Organizer
      生化学夏の学校
    • Place of Presentation
      八王子市、八王子セミナーハウス
    • Year and Date
      2008-08-02
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] インスリン分泌現象の2光子励起解析2008

    • Author(s)
      高橋倫子、河西春郎
    • Organizer
      第52回日本顕微鏡学会シンポジウム
    • Place of Presentation
      千葉市、千葉大学はやき会館
    • Year and Date
      2008-10-18
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Two-photon imaging, uncaging and photoactivation of dendritic spines.2008

    • Author(s)
      H. Kasai
    • Organizer
      Jacques Monod Conference "Investigating brain function using light
    • Place of Presentation
      Roscoff, France
    • Year and Date
      2008-06-22
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] 2光子励起顕微鏡の特徴と医学応用2008

    • Author(s)
      河西春郎
    • Organizer
      ナノ医療工学講義
    • Place of Presentation
      文京区、東京大学工学部
    • Year and Date
      2008-10-16
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Principles of long-term dynamics of dendritic spines.2008

    • Author(s)
      H. Kasai
    • Organizer
      Neuroscience Workshop in NUS
    • Place of Presentation
      Singapore
    • Year and Date
      2008-04-21
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Actin-based plasticity of dendritic spines.2008

    • Author(s)
      H. Kasai
    • Organizer
      US-Japan Workshop
    • Place of Presentation
      Asilomar, USA
    • Year and Date
      2008-02-26
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Imaging of exocytosis and endocytosis with two-photon microscope.2008

    • Author(s)
      Kasai, H.
    • Organizer
      International meeting on Exocytosis
    • Place of Presentation
      Ljublijana, Slovenia
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Protein dynamics during insulin secretion analyzed with two-photonimaging.2008

    • Author(s)
      Noriko Takahashi, Hiroyasu Hatakeyama, Haruo Kasai
    • Organizer
      NanoBio-Seoul 2008
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-10-30
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Two-photon imaging, uncaging and photoactivation of dendritic spines.2008

    • Author(s)
      Kasai, H.
    • Organizer
      Jacques Monod Conference
    • Place of Presentation
      Roscoff, France
    • Year and Date
      2008-06-22
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] 大脳シナプスの2光子顕微鏡による研究2008

    • Author(s)
      河西春郎
    • Organizer
      東京大学大学院薬学系研究科大学院講義
    • Place of Presentation
      文京区、東京大学薬学部
    • Year and Date
      2008-11-06
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Structure dependence of plasticity in dendritic spines.2006

    • Author(s)
      H. Kasai
    • Organizer
      Gordon Research Conference on Synaptic transmission.
    • Place of Presentation
      New London (USA)
    • Year and Date
      2006-07-24
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Stability and plasticity of dendritic spines.2005

    • Author(s)
      H. Kasai
    • Organizer
      Gordon Research Conference on Excitatory Amino Acids.
    • Place of Presentation
      Ausoir (France)
    • Year and Date
      2005-09-13
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Dendritic spine structures critical for spine functions and plasticity.2005

    • Author(s)
      H. Kasai
    • Organizer
      Cold Spring Harbor Symposium on Learning and Memory.
    • Place of Presentation
      Cold Spring Harbor (NY, USA)
    • Year and Date
      2005-04-21
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Two-photon excitation imaging of exocytosis and endocytosis.2004

    • Author(s)
      H. Kasai
    • Organizer
      Gordon Research Conference on Cell Biology of the Neuron.
    • Place of Presentation
      New London (NH, USA)
    • Year and Date
      2004-06-23
    • Data Source
      KAKENHI-PROJECT-16002012
  • [Presentation] Monitoring dynamics of single synapses during circuit plasticity

    • Author(s)
      Haruo Kasai
    • Organizer
      IBRO summer course
    • Place of Presentation
      Seoul
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Two-photon FRET/FLIM imaging of SNARE dependent exocytosis.

    • Author(s)
      Haruo Kasai, Mitsuyo Ohno, Wakako Sawada, Satoshi Watanabe, Noriko Takahashi
    • Organizer
      IUPAB
    • Place of Presentation
      Beijin (China)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] Synaptic competition in the dendritic spines of CA1 pyramidal neurons.

    • Author(s)
      Haruo Kasai
    • Organizer
      高等研国際シンポジウム
    • Place of Presentation
      奈良
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] GABA dependence of synaptic competion in dendritic spines.

    • Author(s)
      Haruo Kasai
    • Organizer
      Max-Planck-Institute/U-Tokyo Symposium
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] 2光子蛍光寿命画像法による開口放出SNARE機構の研究 (Two-photon FRET/FLIM imaging of SNARE dependent exocytosis)

    • Author(s)
      高橋倫子、大野光代、澤田和可子、河西春郎
    • Organizer
      日本生理学会
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] SNARE蛋白の膜拡散 によるインスリン分泌調節の2光子顕微鏡に よる解析

    • Author(s)
      大野光代 高橋倫子 河西春郎
    • Organizer
      第54回日本糖尿病 学会年次学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-21000009
  • [Presentation] SNARE conformation and insulin exocytosis

    • Author(s)
      Noriko Takahashi, Mitsuyo Ohno, Haruo Kasai
    • Organizer
      第54回日本糖尿病 学会年次学術集会シンポジウム
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000009
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