Miyashita Akinori 宮下哲典

… Alternative Names

宮下哲典ミヤシタアキノリ

MIYASHITA Akinori 宮下哲典

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Researcher Number	60323995
Other IDs	https://orcid.org/0000-0003-2508-9649
Affiliation (Current)	2025: 新潟大学, 脳研究所, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 新潟大学, 脳研究所, 准教授 2007 – 2015: 新潟大学, 脳研究所, 助教 2002 – 2006: 新潟大学, 脳研究所, 助手 2002: 新潟大学, 腦研究所, 助手 2001: 新潟大学, 遺伝子実験施設, 助手
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Medical genome science / Human genetics / Laboratory animal science Except Principal Investigator Medical genome science / Basic Section 62010:Life, health and medical informatics-related / Medical genome science / Neurochemistry/Neuropharmacology / System genome science / Biological Sciences … More / Statistical science / Biological Sciences / Neurochemistry/Neuropharmacology / Laboratory animal science Less
Keywords	Principal Investigator アルツハイマー病 / 感受性遺伝子 / ゲノム / 脂質 / 認知症 / 脂質代謝 / ミスセンスバリアント / コモンレアミスセンスバリアント / コモンミスセンスバリアント / レアミスセンスバリアント … More / バリアント / APOE / トランスクリプトーム / 遺伝子発現 / 死後脳 / バイオマーカー / タウ / ゲノム医学 / ゲノム医科学 / ジーントラップ / ES細胞 … More Except Principal Investigator アルツハイマー病 / 遺伝子発現 / 脳組織 / PDZ / RNA / ゲノム / 次世代シークエンサー / 疾患感受性遺伝子 / リスク遺伝子 / システム生物 / 生命情報 / 疾患アトラクター / 深層学習 / 機械学習 / 遺伝子・環境相互作用 / 多因子疾患の発症機序 / 低分子RNA / マイクロRNA / 凍結脳 / 凍結ヒト脳 / miRNA / membrane protein / cell adhesion molecule / immunohistochemistry / adenovirus / coxackie virus / immature neuron / neurogenesis / 大脳皮質 / コクサッキーウイルス / 組織修復期 / 脳形成 / 受容体 / 組織修復 / 細胞接着 / コクッサキーウイルス / 膜タンパク / 細胞接着因子 / 免疫組織化学 / アデノウイルス / コクサッキー / 幼弱ニューロン / 神経新生 / コピー数多型 / マイクロアレイ / コピー数変異 / ポストGWAS / 発現制御 / クロマチン構造 / 核内高次構造 / 神経原繊維変化 / 老人斑 / 培養細胞 / 染色体 / ターゲット分子 / メチル化DNA / 全塩基配列 / エクソーム / 変異 / 家族内発症 / 次世代シークエンス / パーソナルゲノム / シミュレーション / 遺伝子解析 / 陽性反応適中度 / 統計学的検出力 / Joint analysis / Replication-based analysis / 多段階関連解析法 / 症例-対照関連解析 / 医薬生物統計 / マイクロサテライト / ゲノムワイド / 相関解析 / 認知症 / 原因遺伝子 / SNP / 感受性遺伝子 / 脳神経疾患 / ゲノムワイド相関解析 / 遺伝子多型解析 / タイピング支援 / アミロイドβ結合物質 / MC装置 / 亜鉛イオン / アミロイドβ / アンチセンス / ES細胞 / ジーントラップ Less

Missense rare variant analysis of APOE: Exploring the link between lipid metabolism and Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Miyashita Akinori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Niigata University
Systems pathology approach using deep learning to understand the effect of environmental exposure on the pathogenesis of common diseases
- Principal Investigator
  
  荻島創一
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Tohoku University
Molecular analysis of the differentially expressed miRNA related to progression of Alzheimer's disease
- Principal Investigator
  
  Kuwano Ryozo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical genome science
- Research Institution
  Niigata University
Copy number variation database of Alzheimer's disease for genome analysis
- Principal Investigator
  
  Nakaya Akihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  System genome science
- Research Institution
  Osaka University
  Niigata University
Identification of target molecules related the progression of Alzheimer's disease
- Principal Investigator
  
  KUWANO Ryozo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  Niigata University
末梢血におけるアルツハイマー病脳関連遺伝子のエピジェネティック・遺伝子発現解析Principal Investigator
- Principal Investigator
  
  宮下哲典
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical genome science
- Research Institution
  Niigata University
chromosome conformation capture variant technique for disease risk genomic loci
- Principal Investigator
  
  HASEGAWA Mai
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical genome science
- Research Institution
  Niigata University
Personal genome analysis on Alzheimer's disease
- Principal Investigator
  
  KUWANO Ryozo
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Identification and expression analysis of genes controlled by a Alzheimer's disease susceptibility region including APOEPrincipal Investigator
- Principal Investigator
  
  MIYASHITA Akinori
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human genetics
- Research Institution
  Niigata University
Statistical genetics for designing multistage genome-wide association studies to detect genetic risk factors
- Principal Investigator
  
  AKAZAWA Kohei
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Statistical science
- Research Institution
  Niigata University
Genotyping and its use for brain diseases
- Principal Investigator
  
  KUWANO Ryozo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
アルツハイマー病診断・治療薬の開発:βアミロイド結合分子探索からのアプローチ
- Principal Investigator
  
  橘正芳
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Niigata University
アンチセンス転写で形質発現に破綻をきたすダブルジーントラップマウスの開発
- Principal Investigator
  
  KUWANO Ryozo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Niigata University
Identification of immature cells in the adult mouse brain
- Principal Investigator
  
  KUWANO Ryozo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  NIIGATA UNIVERSITY
マウス胚性幹細胞を用いたジーントラップ法によるゲノム欠失型疾患モデルマウスの作出Principal Investigator
- Principal Investigator
  
  宮下哲典
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Niigata University

[Book] アルツハイマー病治療の新たなストラテジー2022
- Author(s)
  宮下哲典、原範和、池内健
- Total Pages
  150
- Publisher
  先端医学社
- ISBN
  4865505407
- Data Source
  KAKENHI-PROJECT-21K07271
[Journal Article] Polygenic effects on the risk of Alzheimer’s disease in the Japanese population2024
- Author(s)
  Kikuchi M et al.
- Journal Title
  
  Alzheimer's Research & Therapy
  
  Volume: 16 Issue: 1 Pages: 0-0
- DOI
  10.1186/s13195-024-01414-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07830, KAKENHI-PROJECT-22K07511, KAKENHI-PROJECT-18K07491, KAKENHI-PROJECT-21K07271, KAKENHI-PROJECT-20H04018, KAKENHI-PROJECT-21H02844
[Journal Article] Heterogenous Genetic, Clinical, and Imaging Features in Patients with Neuronal Intranuclear Inclusion Disease Carrying NOTCH2NLC Repeat Expansion2023
- Author(s)
  Fitrah Yusran Ady、....、Miyashita Akinori、Onodera Osamu、Ikeuchi Takeshi
- Journal Title
  
  Brain Sciences
  
  Volume: 13 Issue: 6 Pages: 955-955
- DOI
  10.3390/brainsci13060955
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03537
[Journal Article] The clinical application of optimized AT(N) classification in Alzheimer’s clinical syndrome (ACS) and non-ACS conditions2023
- Author(s)
  Kasuga Kensaku、Tsukie Tamao、Kikuchi Masataka、Tokutake Takayoshi、Washiyama Kazuo、Shimizu Soichiro、Yoshizawa Hiroshi、Kuroha Yasuko、Yajima Ryuji、Mori Hiroshi、Arakawa Yasuaki、Onda Kiyoshi、Miyashita Akinori、Onodera Osamu、Iwatsubo Takeshi、Ikeuchi Takeshi
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 127 Pages: 23-32
- DOI
  10.1016/j.neurobiolaging.2023.03.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-23K18262, KAKENHI-PROJECT-18K07491, KAKENHI-PROJECT-21H03537
[Journal Article] Amygdala granular fuzzy astrocytes are independently associated with both LATE neuropathologic change and argyrophilic grains: a study of Japanese series with a low to moderate Braak stage2023
- Author(s)
  Yokota Osamu、Miki Tomoko、Nakashima-Yasuda Hanae、Ishizu Hideki、Haraguchi Takashi、Ikeda Chikako、Miyashita Akinori、Ikeuchi Takeshi、Takenoshita Shintaro、Terada Seishi、Takaki Manabu
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 11 Issue: 1 Pages: 148-148
- DOI
  10.1186/s40478-023-01643-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10450, KAKENHI-PROJECT-21H03537
[Journal Article] Novel Partial Deletions, Frameshift and Missense Mutations of CSF1R in Patents with CSF1R-Related Leukoencephalopathy2023
- Author(s)
  Ishiguro Takanobu 、...、Miyashita Akinori , Onodera Osamu , Ikeuchi Takeshi
- Journal Title
  
  European Journal of Neurology
  
  Volume: - Issue: 7 Pages: 1861-1870
- DOI
  10.1111/ene.15796
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03537, KAKENHI-PROJECT-23K24241
[Journal Article] Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes2023
- Author(s)
  Le Guen Yann、.....、Miyashita Akinori、...、Liu Jianjun、Tan Eng-King、EADB、GR@ACE study group、DEGESCO consortium、DemGene、EADI、GERAD、Asian Parkinson’s Disease Genetics consortium
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 36
- DOI
  10.1073/pnas.2302720120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03537
[Journal Article] Clinicopathologic features of two unrelated autopsied patients with Charcot-Marie-Tooth disease carrying MFN2 gene mutation2023
- Author(s)
  Hayashi H, Saito R, Tanaka H, et al.
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 11 Issue: 1 Pages: 207-207
- DOI
  10.1186/s40478-023-01692-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07271, KAKENHI-PROJECT-21H03537, KAKENHI-PROJECT-23H00434
[Journal Article] Actin-binding protein filamin-A drives tau aggregation and contributes to progressive supranuclear palsy pathology2022
- Author(s)
  Tsujikawa K,Hamanaka K, Riku Y, Hattori Y, Hara N, Iguchi Y,Miyata T, Sobue G, Matsumoto N, Sahashi K, Katsuno M, et al.
- Journal Title
  
  Sci Adv
  
  Volume: - Issue: 21 Pages: 1-16
- DOI
  10.1126/sciadv.abm5029
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00527, KAKENHI-PROJECT-22K19506, KAKENHI-PUBLICLY-21H05624, KAKENHI-PROJECT-20H00525, KAKENHI-PROJECT-20H03589, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-21K15330, KAKENHI-PUBLICLY-21H00446, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K21410, KAKENHI-PROJECT-21H03537
[Journal Article] Amygdala granular fuzzy astrocytes as lesions preceding development of argyrophilic grains: data from 239 autopsy cases2022
- Author(s)
  Yokota Osamu 、Miki Tomoko、Ikeda Chikako 、Ishizu Hideki 、Haraguchi Takashi 、Miyashita Akinori 、Ikeuchi Takeshi 、Takenoshita Shintaro 、Terada Seishi 4.巻 3
- Journal Title
  
  Free Neuropathology
  
  Volume: 3 Pages: 1-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03537
[Journal Article] Identification of mild cognitive impairment subtypes predicting conversion to Alzheimer’s disease using multimodal data2022
- Author(s)
  Kikuchi M, Kobayashi K, Itoh S, Kasuga K, Miyashita A, Ikeuchi T, Yumoto E, Kosaka Y, Fushimi Y, Takeda T, Manabe S, Hattori S; Alzheimer's Disease Neuroimaging Initiative; Nakaya A, Kamijo K, Matsumura Y
- Journal Title
  
  Computational and Structural Biotechnology Journal
  
  Volume: 20 Pages: 5296-5308
- DOI
  10.1016/j.csbj.2022.08.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06629, KAKENHI-PROJECT-20K07196, KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-21H03537
[Journal Article] SYNE1-ataxia: clinicopathologic features of an autopsied patient with novel compound heterozygous mutations2022
- Author(s)
  Saito Rie、Hara Norikazu、Tada Mari、Wakabayashi Masatoshi、Miyashita Akinori、Nishizawa Masatoyo、Onodera Osamu、Ikeuchi Takeshi、Kakita Akiyoshi
- Journal Title
  
  Journal of Neuropathology & Experimental Neurology
  
  Volume: 82 Issue: 3 Pages: 267-271
- DOI
  10.1093/jnen/nlac120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24256, KAKENHI-PROJECT-21H03537
[Journal Article] Genetics of Alzheimer’s disease: an East Asian perspective2022
- Author(s)
  Miyashita Akinori、Kikuchi Masataka、Hara Norikazu、Ikeuchi Takeshi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 3 Pages: 115-124
- DOI
  10.1038/s10038-022-01050-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07271, KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-21H03537
[Journal Article] Biallelic COX10 Mutations and PMP22 Deletion in a Family With Leigh Syndrome and Hereditary Neuropathy With Liability to Pressure Palsy2022
- Author(s)
  Kuroha Yasuko、....、 Miyashita Akinori、.....、 Ikeuchi Takeshi
- Journal Title
  
  Neurology Genetics
  
  Volume: 8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03537
[Journal Article] Different AT(N) profiles and clinical progression classified by two different N markers using total tau and neurofilament light chain in cerebrospinal fluid2022
- Author(s)
  Kasuga Kensaku、Kikuchi Masataka、Tsukie Tamao、Suzuki Kazushi、Ihara Ryoko、Iwata Atsushi、Hara Norikazu、Miyashita Akinori、Kuwano Ryozo、Iwatsubo Takeshi、Ikeuchi Takeshi、collaboration author: Masaki Ikeda
- Journal Title
  
  BMJ Neurology Open
  
  Volume: 4 Issue: 2 Pages: e000321-e000321
- DOI
  10.1136/bmjno-2022-000321
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07491, KAKENHI-PROJECT-22K07511, KAKENHI-PROJECT-22K07549, KAKENHI-PROJECT-22H04961, KAKENHI-PROJECT-21H02844, KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-21H03537
[Journal Article] Biallelic COX10 Mutations and PMP22 Deletion in a Family With Leigh Syndrome and Hereditary Neuropathy With Liability to Pressure Palsy2022
- Author(s)
  Kuroha Yasuko、....、 Miyashita Akinori、.....、 Ikeuchi Takeshi
- Journal Title
  
  Neurology Genetics
  
  Volume: 8 Issue: 5
- DOI
  10.1212/nxg.0000000000200030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03537
[Journal Article] Brain TDP‐43 pathology in corticobasal degeneration: Topographical correlation with neuronal loss2022
- Author(s)
  Sainouchi Makoto、Tada Mari、Fitrah Yusran Ady、Hara Norikazu、Tanaka Kou、Idezuka Jiro、Aida Izumi、Nakajima Takashi、Miyashita Akinori、Akazawa Kohei、Ikeuchi Takeshi、Onodera Osamu、Kakita Akiyoshi
- Journal Title
  
  Neuropathology and Applied Neurobiology
  
  Volume: 48 Issue: 3
- DOI
  10.1111/nan.12786
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07972, KAKENHI-PROJECT-21H03537
[Journal Article] Four‐repeat tauopathies and late‐onset psychiatric disorders: Etiological relevance or incidental findings?2022
- Author(s)
  Yokota Osamu、Miki Tomoko、Ishizu Hideki、Haraguchi Takashi、Kishimoto Yuki、Takenoshita Shintaro、Hara Norikazu、Miyashita Akinori、Ikeuchi Takeshi、Terada Seishi、Yamada Norihito
- Journal Title
  
  Neuropathology
  
  Volume: 43 Issue: 1 Pages: 51-71
- DOI
  10.1111/neup.12820
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03537
[Journal Article] A functional variant of SHARPIN confers increased risk of late-onset Alzheimer’s disease2021
- Author(s)
  Asanomi Yuya、Shigemizu Daichi、Akiyama Shintaro、Miyashita Akinori、Mitsumori Risa、Hara Norikazu、Ikeuchi Takeshi、Niida Shumpei、Ozaki Kouichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 67 Issue: 4 Pages: 203-208
- DOI
  10.1038/s10038-021-00987-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03537
[Journal Article] Network-Based Analysis for Uncovering Mechanisms Underlying Alzheimer's Disease.2016
- Author(s)
  Kikuchi M, Ogishima S, Mizuno S, Miyashita A, Kuwano R, Nakaya J, Tanaka H.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1303 Pages: 479-91
- DOI
  10.1007/978-1-4939-2627-5_29
- ISBN
  9781493926268, 9781493926275
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25330333, KAKENHI-PROJECT-26640122, KAKENHI-PROJECT-26240044
[Journal Article] AlzPathway, an Updated Map of Curated Signaling Pathways: Towards Deciphering Alzheimer's Disease Pathogenesis.2016
- Author(s)
  Ogishima S, Mizuno S, Kikuchi M, Miyashita A, Kuwano R, Tanaka H, Nakaya J.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1303 Pages: 423-32
- DOI
  10.1007/978-1-4939-2627-5_25
- ISBN
  9781493926268, 9781493926275
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25330333, KAKENHI-PROJECT-26640122, KAKENHI-PROJECT-26240044
[Journal Article] Genes associated with the progression of neurofibrillary tangles in Alzheimer's disease2014
- Author(s)
  Akinori Miyashita, Hiroyuki Hatsuta, Masataka Kikuchi, Akihiro Nakaya, Yuko Saito, Tamao Tsukie, Norikazu Hara, Soichi Ogishima, Nobutaka Kitamura, Kohei Akazawa, Akiyoshi Kakita, Hitoshi Takahashi, Shigeo Murayama, Yasuo Ihara, Takeshi Ikeuchi, and Ryozo Kuwano
- Journal Title
  
  Translational Psychiatry
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430181
[Journal Article] Clinical and neuroimaging features of patient with early-onset Parkinson's disease with dementia carrying SNCA p.G51D mutation.2014
- Author(s)
  Tokutake T, Ishikawa A, Yoshimura N, Miyashita A, Kuwano R, Nishizawa M, Ikeuchi T
- Journal Title
  
  Parkinsonism Relat Disord
  
  Volume: 20 Issue: 2 Pages: 262-264
- DOI
  10.1016/j.parkreldis.2013.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PROJECT-24310144, KAKENHI-PROJECT-25893077
[Journal Article] Genes associated with the progression of neurofibrillary tangles in Alzheimer’s disease2014
- Author(s)
  Miyashita A　ほか
- Journal Title
  
  Translational Psychiatry
  
  Volume: 4 Issue: 6 Pages: e396-e396
- DOI
  10.1038/tp.2014.35
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PROJECT-24310144
[Journal Article] Genes associated with the progression of neurofibrillary tangles in Alzheimer’s disease2014
- Author(s)
  Miyashita A, Hatsuta H, Kikuchi M, Nakaya A, Saito Y, et al.
- Journal Title
  
  Transl Psychiatry
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510275
[Journal Article] Lack of genetic association between TREM2 and late-onset Alzheimer’s disease in a Japanese population2014
- Author(s)
  Akinori Miyashitaa, Yanan Wen　他
- Journal Title
  
  J Alzheimer's Dis.
  
  Volume: 印刷中 Issue: 4 Pages: 1301-1308
- DOI
  10.3233/jad-140225
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-24310144, KAKENHI-PROJECT-24390179, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24700371, KAKENHI-PROJECT-25670415, KAKENHI-PROJECT-26460907, KAKENHI-PROJECT-26461264
[Journal Article] Lack of genetic association between TREM2 and late-onset Alzheimer’s disease in a Japanese population2014
- Author(s)
  Miyashita A, Wen Y, Kitamura N, Matsubara E, Kawarabayashi T, et al.
- Journal Title
  
  J Alzheimers Dis
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510275
[Journal Article] SORL1 is genetically associated with neuropathologically characterized late-onset Alzheimer's disease2013
- Author(s)
  Wen Y, Miyashita A, Kitamura N, Tsukie T, Saito Y, Hatsuta H, Murayama S, et al.
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 35(2) Issue: 2 Pages: 387-94
- DOI
  10.3233/jad-122395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590968, KAKENHI-PROJECT-24310144, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24510275, KAKENHI-PROJECT-24650149, KAKENHI-PROJECT-24700371, KAKENHI-PROJECT-221S0002, KAKENHI-PLANNED-22129004
[Journal Article] A map of Alzheimer'sdisease-signaling pathways: a hope for drug target discovery2013
- Author(s)
  Ogishima S, Mizuno S, Kikuchi M, Miyashita A, Kuwano R, Tanaka H, Nakaya J.
- Journal Title
  
  Clin Pharmacol Ther
  
  Volume: 93(5) Issue: 5 Pages: 399-401
- DOI
  10.1038/clpt.2013.37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700311, KAKENHI-PROJECT-24510275, KAKENHI-PROJECT-25330333, KAKENHI-PLANNED-22129004
[Journal Article] 15. Identification of unstable network modules reveals disease modules associated with the progression of Alzheimer's disease2013
- Author(s)
  Kikuchi M, Ogishima S, Miyamoto T, Miyashita A, Kuwano R, Nakaya J, Tanaka H
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 11 Pages: e76162-e76162
- DOI
  10.1371/journal.pone.0076162
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PROJECT-24310144, KAKENHI-PROJECT-25330333
[Journal Article] SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians2013
- Author(s)
  Miyashita A, Koike A, Jun G, Kawarabayashi T, Shoji M,Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Ikeuchi T, St. George-Hyslop P,
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e58618-e58618
- DOI
  10.1371/journal.pone.0058618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-23591234, KAKENHI-PROJECT-23591706, KAKENHI-PROJECT-23659450, KAKENHI-PROJECT-24310144, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24510275, KAKENHI-PROJECT-24591246, KAKENHI-PROJECT-25670415, KAKENHI-PROJECT-221S0002, KAKENHI-PLANNED-22129004
[Journal Article] Alteration of P0LDIP3 Splicing Associated with Loss of Function of TDP-43 in Tissues Affected with ALS2012
- Author(s)
  Shiga A, et al ;
- Journal Title
  
  PLoS ONE
  
  Volume: 7(8) Issue: 8 Pages: e43120-e43120
- DOI
  10.1371/journal.pone.0043120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07914, KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23890060, KAKENHI-PROJECT-24510275, KAKENHI-PROJECT-24790875, KAKENHI-PLANNED-22129004
[Journal Article] AlzPathway: a comprehensive map of signaling pathways of Alzheimer'sdisease2012
- Author(s)
  Mizuno S, Iijima R, Ogishima S, Kikuchi M, Matsuoka Y, Ghosh S, Miyamoto T, Miyashita A, Kuwano R, Tanaka H.
- Journal Title
  
  BMC Syst Biol
  
  Volume: 6 Issue: 1 Pages: 52-52
- DOI
  10.1186/1752-0509-6-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700311, KAKENHI-PROJECT-24510275, KAKENHI-PLANNED-22129004
[Journal Article] Evidence for a Common Founder and Clinical Characteristics of Japanese Families with the MAPT R406W Mutation2011
- Author(s)
  Ikeuchi T, Imamura T, Kawase Y, Kitade Y, Tsuchiya M, Tokutake T, Kasuga K, Yajima R, Tsukie T, Miyashita A, Sugishita M, Kuwano R, Nishizawa M
- Journal Title
  
  Dement Geriatr Cogn Disord Extra
  
  Volume: 1 Pages: 267-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] 検査診断学とバイオマーカー:概論2011
- Author(s)
  桑野良三, 宮下哲典, 月江珠緒
- Journal Title
  
  日本臨床
  
  Volume: 69(増刊号8) Pages: 476-483
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] Apolipoprotein E遺伝子2011
- Author(s)
  桑野良三, 宮下哲典
- Journal Title
  
  日本臨床
  
  Volume: 69(増刊号8) Pages: 93-97
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] 認知症のイメージングゲノミクス2011
- Author(s)
  宮下哲典, 桑野良三
- Journal Title
  
  別冊・医学のあゆみ
  
  Pages: 57-61
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] 遺伝子診断とイメージング・ジェネティクス2011
- Author(s)
  宮下哲典, 桑野良三
- Journal Title
  
  日本臨床
  
  Volume: 69(増刊号8) Pages: 565-569
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] 認知症のイメージングゲノミクス2010
- Author(s)
  宮下哲典, 桑野良三
- Journal Title
  
  医学のあゆみ
  
  Volume: 235(6) Pages: 663-667
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] TRPM7 Is Not Associated With Amyotrophic Lateral Sclerosis-Parkinsonism Dementia Complex in the Kii Peninsula of Japan2010
- Author(s)
  Hara K, Kokubo Y, Ishiura H, Fukuda Y, Miyashita A, Kuwano R, Sasaki R, Goto J, Nishizawa M, Kuzuhara S, Tsuji S
- Journal Title
  
  Am J Med Genet Part B
  
  Volume: 153B Pages: 310-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] Neuroblastoma amplified sequence gene is associated with a novel short stature syndrome characterised by optic nerve atrophy and Pelger-Huet anomaly2010
- Author(s)
  Maksimova N, Hara K, Nikolaeva I, Chun-Feng T, Usui T, Takagi M, Nishihira Y, Miyashita A, Fujiwara H, Oyama T, Nogovicina A, Sukhomyasova A, Potapova S, Kuwano R, Takahashi H, Nishizawa M, Onodera O
- Journal Title
  
  J Med Genet
  
  Volume: 47 Pages: 538-548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] 認知症性疾患の遺伝子と病態・認知症の遺伝子異常2010
- Author(s)
  宮下哲典, 桑野良三
- Journal Title
  
  認知症診療マニュアル
  
  Volume: 72(Suppl. 6) Pages: 40-45
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] Sporadic four-repeat tauopathy with frontotemporal lobar degeneration, Parkinsonism, and motor neuron disease : a distinct clinicopathological and biochemical disease entity2010
- Author(s)
  Fu YJ, Nishihira Y, Kuroda S, Toyoshima Y, Ishihara T, Shinozaki M, Miyashita A, Piao YS, Tan CF, Tani T, Koike R, Iwanaga K, Tsujihata M, Onodera O, Kuwano R, Nishizawa M, Kakita A, Ikeuchi T, Takahashi H
- Journal Title
  
  Acta Neuropathol
  
  Volume: 120 Pages: 21-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] Genetic deficiency of plasma lipoprotein-associated phospholipase A2(PLA2G7 V297F null mutation) and risk of Alzheimer's disease in Japan2010
- Author(s)
  Koshy B, Miyashita A, St Jean P, Stirnadel H, Kaise T, Rubio JP, Mooser V, Kuwano R, Irizarry MC
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 21 Pages: 775-780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790331
[Journal Article] Hoque MA: Programs for calculating the statistical powers of detecting susceptibility genes in case-control studies based on multistage designs2009
- Author(s)
  Kitamura N, Akazawa K, Miyashita A, Kuwano R, Toyabe SI, Nakamura J, Nakamura N, Sato T
- Journal Title
  
  Bioinformatics 25
  
  Pages: 272-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] Programs for calculating the statistical powers of detecting susceptibility genes in case-control studies based on multistage designs2009
- Author(s)
  Kitamura N, Akazawa K, Miyashita A, Kuwano R, Toyabe SI, Nakamura J, Nakamura N, Sato T, Hoque MA
- Journal Title
  
  Bioinformatics 25(2)
  
  Pages: 272-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300095
[Journal Article] SNP HiTLink: a high-throughput linkage analysis system employing dense SNP data2009
- Author(s)
  Fukuda Y, Nakahara Y, Date H, Takahashi Y, Goto J, Miyashita A, Kuwano R, Adachi H, Nakamura E, Tsuji S.
- Journal Title
  
  BMC Bioinformatics 10
  
  Pages: 121-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] Depression and psychiatric symptoms preceding onset of dementia in a family with early-onset Alzheimer disease with a novel PSEN1 mutation2009
- Author(s)
  Kasuga K, Ohno T, Ishihara T, Miyashita A, Kuwano R, Onodera O, Nishizawa M, Ikeuchi T.
- Journal Title
  
  J Neurol 256
  
  Pages: 1351-1353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] GAB2 is not associated with late-onset Alzheimer's disease in Japanese2009
- Author(s)
  Miyashita A, Arai H, Asada T, Imagawa M, Shoji M, Higuchi S, Urakami K, Toyabe S, Akazawa K, Kanazawa I, Ihara Y, Kuwano R.
- Journal Title
  
  Eur J Hum Genet 17
  
  Pages: 682-686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese2009
- Author(s)
  Takei N, Miyashita A, Tsukie T, Arai H, Asada T, Imagawa M, Shoji M, Higuchi S, Urakami K, Kimura H, Kakita A, Takahashi H, Tsuji S, Kanazawa I, Ihara Y, Odani S, Kuwano R, the Japanese Genetic Study Consortium for Alzheimer Disease
- Journal Title
  
  Genomics 93
  
  Pages: 441-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] GAB2 is not associated with late-onset Alzheimer's disease in Japanese2009
- Author(s)
  Miyashita A.
- Journal Title
  
  Eur J Hum Genet (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease2009
- Author(s)
  Hara K, Shiga A, Fukutake T, Nozaki H, Miyashita A, Yokoseki A, Kawata H, Koyama A, Arima K, Takahashi T, Ikeda M, Shiota H, Tamura M, Shimoe Y, Hirayama M, Arisato T, Yanagawa S, Tanaka A, Nakano I, Ikeda S, Yoshida Y, Yamamoto T, Ikeuchi T, Kuwano R, Nishizawa M, Tsuji S, Onodera O.
- Journal Title
  
  N Engl J Med 360
  
  Pages: 1729-1739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] Prediction of Disease-associated Single Nucleotide Polymorphisms Using Virtual Genomes Constructed from a Public Haplotype Database2008
- Author(s)
  Toyabe S, Miyashita A, Kitamura N, Kuwano R, Akazawa K
- Journal Title
  
  Methods Inf Med 47(6)
  
  Pages: 522-528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300095
[Journal Article] Mutational analysis in early-onset familial dementia in the Japanese population. The role of PSEN1 and MAPT R406W mutations2008
- Author(s)
  Ikeuchi T, Kaneko H, Miyashita A, Nozaki H, Kasuga K, Tsukie T, Tsuchiya M, Imamura T, Ishizu H, Aoki K, Ishikawa A, Onodera O, Kuwano R, Nishizawa M
- Journal Title
  
  ement Geriatr Cogn Disord 26(1)
  
  Pages: 43-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] Prediction of Disease-associated Single Nucleotide Polymorphisms Using Virtual Genomes Constructed from a Public Haplotype Database2008
- Author(s)
  Toyabe S, Miyashita A, Kitamura N, Kuwano R, Akazawa K
- Journal Title
  
  Methods Inf Med 47(6)
  
  Pages: 522-528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] Sample-size properties of a case-control association analysis of multistage SNP studies for identifying disease susceptibility genes.2008
- Author(s)
  Kitamura N, Akazawa K, Toyabe SI, Miyashita A, Kuwano R, Nakamura J
- Journal Title
  
  Journal of Human Genetics (印刷中)
- NAID
  10021248775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300095
[Journal Article] Sample-size properties of a case-control association analysis of multistage SNP studies for identifying disease susceptibility genes2008
- Author(s)
  Kitamura N, Akazawa K, Toyabe SI, Miyashita A, Kuwano R, Nakamura J
- Journal Title
  
  J Hum Genet 53(5)
  
  Pages: 390-400
- NAID
  10021248775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300095
[Journal Article] Genetic association of CTNNA3 with late-onset Alzheimer's disease in females2007
- Author(s)
  Miyashita A, Arai H, Asada T, Imagawa M, Matsubara E, Shoji M, Higuchi S, Urakami K, Kakita A, Takahashi H, Toyabe S, Akazawa K, Kanazawa I, Ihara Y, Kuwano R.
- Journal Title
  
  Human Molecular Genetics 16(23)
  
  Pages: 2854-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300095
[Journal Article] Genetic association of CTNNA3 with late-onset Alzheimer's disease in females2007
- Author(s)
  Miyashita A, Arai H, Asada T, Imagawa M, Matsubara E, Shoji M, Higuchi S, Urakami K, Kakita A, Takahashi H, Toyabe S, Akazawa K, Kanazawa I, Ihara Y, Kuwano R
- Journal Title
  
  Human Molecular Genetics 16(23)
  
  Pages: 2854-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300095
[Journal Article] Genetic association of CTNNA3 with late-onset Alzheimer's disease in females2007
- Author(s)
  Miyashita A
- Journal Title
  
  Hum Mol Genet 16
  
  Pages: 2854-2869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] Genetic association of CTNNA3 with late-onset Alzheimer‘s disease in females2007
- Author(s)
  Miyashita A, Arai H, Asada T, Imagawa M, Matsubara E, Shoji M, Higuchi S, Urakami K, Kakita A, Takahashi H, Toyabe S, Akazawa K, Kanazawa I, Ihara Y, Kuwano R
- Journal Title
  
  Hum Mol Genet 16(23)
  
  Pages: 2854-2869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17020004
[Journal Article] Japanese Genetic Study Consortium for Alzeheimer's Disease. Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease2006
- Author(s)
  Kuwano R, Miyashita A, Arai H, Asada T, Imagawa M, Shoji M, Higuchi S, Urakami K, Kakita A, Takahashi H, Tsukie T, Toyabe S, Akazawa K, Kanazawa I, Ihara Y
- Journal Title
  
  Hum Mol Genet. 15
  
  Pages: 2170-2182
- Data Source
  KAKENHI-PROJECT-17020004
[Presentation] 認知症のトランスクリプトーム解析：ヒト剖検脳のシングル核解析から見えてくるもの2023
- Author(s)
  宮下哲典、他田真理、原範和、長谷川舞衣、柿田明美、池内健
- Organizer
  第41回（2022年）日本認知症学会学術集会（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-21K07271
[Presentation] APOEコモン・レアミスセンスレアバリアント2023
- Author(s)
  宮下哲典
- Organizer
  The ApoEーapoE好きがapoEについて語る会ー
- Invited
- Data Source
  KAKENHI-PROJECT-21K07271
[Presentation] ヒト剖検脳におけるAD、LATE、PARTの感受性バリアント解析2022
- Author(s)
  宮下哲典、金田大太、原範和、月江珠緒、長谷川舞衣、春日健作、橋詰良夫、池内健
- Organizer
  第41回（2022年）日本認知症学会学術集会（東京）
- Data Source
  KAKENHI-PROJECT-21K07271
[Presentation] アルツハイマー病感受性領域が近接する染色体領域の同定2015
- Author(s)
  菊地正隆, 原範和, 長谷川舞衣, 宮下哲典, 桑野良三, 池内健, 中谷明弘
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  リンクステーション青森・ホテル青森
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-25430181
[Presentation] アルツハイマー病感受性領域が近接する染色体領域の同定2015
- Author(s)
  菊地正隆、原範和、長谷川舞衣、宮下哲典、桑野良三、池内健、中谷明弘
- Organizer
  第３４回日本認知症学会
- Place of Presentation
  リンクステーションホール（青森県、青森市）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26640122
[Presentation] Identification of chromosomal regions interacting with susceptibility loci for Alzheimer’s disease2015
- Author(s)
  Kikuchi M, Hara N, Hasegawa M, Miyashita A, Kuwano R, Ikeuchi T, and Nakaya A
- Organizer
  American Society of Human Genetics Annual Meeting 2015
- Place of Presentation
  Baltimore, MD, USA
- Year and Date
  2015-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430181
[Presentation] アルツハイマー病感受性領域が近接する染色体領域の同定2015
- Author(s)
  菊地正隆, 原範和, 長谷川舞衣, 宮下哲典, 桑野良三, 池内健, 中谷明弘
- Organizer
  日本人類遺伝学会第60回大会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-25430181
[Presentation] AD/GD CNVdb (Alzheimer's Disease Genomic Databases, Copy Number Variation Database)2015
- Author(s)
  Nakaya A, Kikuchi M, Miyashita A, Hara N, Kasuga K, Nishida N, Tokunaga K, Kuwano R, and Ikeuchi T
- Organizer
  日本バイオインフォマティクス学会2015年年会
- Place of Presentation
  京都大学宇治キャンパスおうばくプラザ
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-25430181
[Presentation] Genomic structure and distribution of copy number variations in relation to Japanese Alzheimer's disease2015
- Author(s)
  Nakaya A, Kikuchi M, Miyashita A, Hara N, Kasuga K, Nishida N, Tokunaga K, Kuwano R, and Ikeuchi T
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25430181
[Presentation] アルツハイマー病感受性領域が近接する染色体領域の同定2015
- Author(s)
  菊地正隆, 原範和, 長谷川舞衣, 宮下哲典, 桑野良三, 池内健, 中谷明弘
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25430181
[Presentation] アルツハイマー病の血清バイオマーカーとしてのマイクロRNA解析2015
- Author(s)
  原範和、菊地正隆、宮下哲典、初田裕幸、齊藤祐子、村山繁雄、春日健作、池内健、桑野良三
- Organizer
  第３４回日本認知症学会
- Place of Presentation
  リンクステーションホール（青森県、青森市）
- Year and Date
  2015-10-03
- Data Source
  KAKENHI-PROJECT-26640122
[Presentation] 細胞特異的な染色体高次構造は遺伝子発現を調節するのか?2014
- Author(s)
  菊地正隆, 長谷川舞衣, 原範和, 宮下哲典, 中谷明弘, 池内健, 桑野良三
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-25430181
[Presentation] AD/GD CNVdb: アルツハイマー病のコピー数変異データベース2013
- Author(s)
  中谷明弘, 宮下哲典, 菊地正隆, 長谷川舞衣, 原範和, 西田奈央, 徳永勝士, 井原康夫, 池内健, 桑野良三
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25430181
[Presentation] 2）細胞特異的なゲノム高次構造解析法の検討2013
- Author(s)
  長谷川舞衣, 原範和, 菊地正隆, 宮下哲典, 中谷明弘, 池内健, 桑野良三
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-22129004
[Presentation] AD/GD CNVdb: アルツハイマー病のコピー数変異データベース.2013
- Author(s)
  中谷明弘, 宮下哲典, 菊地正隆, 長谷川舞衣, 原範和, 西田奈央, 徳永勝士, 井原康夫, 池内健, 桑野良三
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-22129004
[Presentation] SORL1 is Genetically Associated With Late-Onset Alzheimer's Disease in Japanese, Koreans and Caucasians.2013
- Author(s)
  Miyashita A, Kuwano R, Schellenberg G, Ihara Y, Kanazawa I, Tsuji S, Yamamoto K, Tokunaga K, Nishida N, Yoshida M, Pericak-Vance M, Haines J, Mayeux R, St. George-Hyslop P, Kim JW, Takahashi S, Wang LS, Jun G, Koike A, Farrer L
- Organizer
  AAIC
- Place of Presentation
  アメリカ、ボストン
- Data Source
  KAKENHI-PLANNED-22129004
[Presentation] 細胞特異的なゲノム高次構造解析法の検討2013
- Author(s)
  長谷川舞衣,原範和,菊地正隆,宮下哲典,中谷明弘,池内健,桑野良三
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-24651221
[Presentation] SORL1 is Genetically Associated With Late-Onset Alzheimer's Disease in Japanese, Koreans and Caucasians2013
- Author(s)
  Miyashita A, Kuwano R, Schellenberg G, Ihara Y, Kanazawa I, Tsuji S, Yamamoto K, Tokunaga K, Nishida N, Yoshida M, Pericak-Vance M, Haines J, Mayeux R, St. George-Hyslop P, Kim JW, Takahashi S, Wang LS, Jun G, Koike A, Farrer L
- Organizer
  Alzheimer's Association International Conference 2013
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24510275
[Presentation] AD/GD CNVdb : アルツハイマー病のコピー数変異データベース2013
- Author(s)
  中谷明弘,宮下哲典,菊地正隆,長谷川舞衣,原範和,西田奈央,徳永勝士,井原康夫,池内健,桑野良三
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-24651221
[Presentation] SORL1 is Genetically Associated With Late-Onset Alzheimer's Disease in Japanese, Koreans and Caucasians.2013
- Author(s)
  Miyashita A, Kuwano R, Schellenberg G, Ihara Y, Kanazawa I, Tsuji S, Yamamoto K, Tokunaga K, Nishida N, Yoshida M, Pericak-Vance M, Haines J, Mayeux R, St. George-Hyslop P, Kim JW, Takahashi S, Wang LS, Jun G, Koike A, Farrer L
- Organizer
  AAIC
- Place of Presentation
  アメリカ、ボストン
- Data Source
  KAKENHI-PROJECT-24310144
[Presentation] 細胞特異的なゲノム高次構造解析法の検討2013
- Author(s)
  長谷川舞衣, 原範和, 菊地正隆, 宮下哲典, 中谷明弘, 池内健, 桑野良三
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24310144
[Presentation] 細胞特異的なゲノム高次構造解析法の検討2013
- Author(s)
  長谷川舞衣, 原範和, 菊地正隆, 宮下哲典, 中谷明弘, 池内健, 桑野良三
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県）
- Data Source
  KAKENHI-PROJECT-24651221
[Presentation] 細胞特異的な転写制御にかかわるゲノム高次構造の解析法の検討2013
- Author(s)
  長谷川舞衣,原範和,菊地正隆,中谷明弘,宮下哲典,池内健,桑野良三
- Organizer
  第43回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センターセミナーホール(新潟県新潟市)
- Year and Date
  2013-07-26
- Data Source
  KAKENHI-PROJECT-24651221
[Presentation] 晩期発症型アルツハイマー病とTREM2の関連解析2013
- Author(s)
  宮下哲典, 温雅楠, 初田裕幸, 村山繁雄, 山口晴保, 赤津裕康, 柿田明美, 高橋均, 井原康夫, 池内健, 桑野良三
- Organizer
  第32回日本認知症学会
- Place of Presentation
  長野県松本市
- Data Source
  KAKENHI-PROJECT-24510275
[Presentation] AD/GD CNVdb: アルツハイマー病のコピー数変異データベース2013
- Author(s)
  中谷明弘, 宮下哲典, 菊地正隆, 長谷川舞衣, 原範和, 西田奈央, 徳永勝士, 井原康夫, 池内健, 桑野良三
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県）
- Data Source
  KAKENHI-PROJECT-24651221
[Presentation] 細胞特異的な転写制御にかかわるゲノム高次構造の解析法の検討2013
- Author(s)
  長谷川舞衣, 原範和, 菊地正隆, 中谷明弘, 宮下哲典, 池内健, 桑野良三
- Organizer
  第４３回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学（新潟県）
- Data Source
  KAKENHI-PROJECT-24651221
[Presentation] Gene expression analysis in the postmortem brains classified by Braak NFT-SP staging2012
- Author(s)
  Miyashita A
- Organizer
  the Alzheimer's Association International Conference (AAIC)
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PLANNED-22129004
[Presentation] アルツハイマー病のコピー数多型解析（Copy number variation analysis of Alzheimer's disease）.2012
- Author(s)
  中谷明弘, 宮下哲典, 西田奈央, 徳永勝士, 井原康夫, 桑野良三（Akihiro Nakaya, Akinori Miyashita, Nao Nishida, Katsusi Tokunaga, Yasuo Ihara, Ryozo Kuwano）.
- Organizer
  第35回日本分子生物学会年会.
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-24510275
[Presentation] The Japanese Alzheimer's Disease Neuroimaging Initiative. Biomarker for diagnosis of Alzheimer's disease2012
- Author(s)
  Ryozo Kuwano, Tamao Tsukie, Akinori Miyashita, Takeshi Ikeuchi, Akihiro Nakaya, Takeshi Iwatsubo
- Organizer
  42nd NIPS International Symposium-NIPS and BRI Niigata University Joint Symposium-
- Place of Presentation
  岡崎
- Year and Date
  2012-03-06
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] アルツハイマー病とSORL1の関連解析.2012
- Author(s)
  宮下哲典, 温雅楠, 月江珠緒, 桑野良三.
- Organizer
  第31回日本認知症学会.
- Place of Presentation
  茨城県つくば市
- Data Source
  KAKENHI-PROJECT-24510275
[Presentation] Gene expression analysis in the postmortem brains classified by Braak NFT-SP staging.2012
- Author(s)
  Miyashita A, Saito Y, Hatsuta H, Tsukie T, Nakaya A, Murayama S, Ihara Y, Kuwano R.
- Organizer
  Alzheimer's Association International Conference 2012.
- Place of Presentation
  Vancouver, Canada.
- Data Source
  KAKENHI-PROJECT-24510275
[Presentation] Gene expression profiling in the postmortem brains classified by Braak neurofibrillary tangle staging2011
- Author(s)
  Miyashita A, Saito Y, Hatsuta H, Tsukie T, Murayama S, Ihara Y, Kuwano R
- Organizer
  Alzheimer's Association International Conference 2011
- Place of Presentation
  Paris
- Year and Date
  2011-07-17
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] 日本人における晩期発症型アルツハイマー病のGWAS (Genome-wide association study of late-onset Alzheimer's disease in Japanese)2011
- Author(s)
  桑野良三, ら(宮下哲典共同演者・2番目)
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  神奈川,横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] アルツハイマー病のゲノム・遺伝子発現解析2011
- Author(s)
  宮下哲典,月江珠緒,中谷明弘,桑野良三
- Organizer
  新潟脳神経研究会第294回例会
- Place of Presentation
  新潟
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] アルツハイマー病脳の遺伝子発現プロファイリング2011
- Author(s)
  宮下哲典,齋藤祐子,初田裕幸,月江珠緒,村山繁雄,井原康夫,中谷明弘,桑野良三
- Organizer
  第30回日本認知症学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] Gene expression profiling in the postmortem brains classified by Braak neurofibrillary tangle staging2011
- Author(s)
  Miyashita A, et al
- Organizer
  Alzheimer's Association International Conference 2011
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-17
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] アルツハイマー病脳における遺伝子発現解析2011
- Author(s)
  宮下哲典,月江珠緒,齊藤祐子,初田裕幸,中谷明弘,村山繁雄,井原康夫,桑野良三
- Organizer
  Bio Japan2011
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] Genome-wide association study of late-onset Alzheimer's disease in Japanese2011
- Author(s)
  Ryozo Kuwano, Akinori Miyashita, Asako Koike, Nao Nishida, Katsusi Tokunaga, Ken Yamamoto, Shoji Tsuji, Yasuo Ihara
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] アルツハイマー病脳の遺伝子発現プロファイリング2011
- Author(s)
  宮下哲典, ら
- Organizer
  第30回日本認知症学会
- Place of Presentation
  東京,江戸川区
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] アルツハイマー病脳における遺伝子発現解析2010
- Author(s)
  宮下哲典,月江珠緒,齊藤祐子,初田裕幸,村山繁雄,桑野良三
- Organizer
  第28回バイオテクノロジーシンポジウム
- Place of Presentation
  横浜
- Year and Date
  2010-09-29
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] アルツハイマー病脳組織におけるSORL1の遺伝子発現解析2010
- Author(s)
  温雅楠,宮下哲典,月江珠緒,齋藤祐子,初田裕幸,村山繁雄,柿田明美,高橋均,北村信隆,赤澤宏平,井原康夫,桑野良三
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] 脳脊髄液中のアミロイドβ,総タウリン酸化タウ測定条件の検討2010
- Author(s)
  月江珠緒,宮下哲典,池内健,角田伸人,高橋智,桑野良三
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] 死後脳におけるアルツハイマー病関連遺伝子の発現プロファイリング2010
- Author(s)
  宮下哲典,齋藤祐子,初田裕幸,月江珠緒,村山繁雄,井原康夫,桑野良三
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] 後部帯状回と楔前部におけるアミロイドβ沈着2010
- Author(s)
  初田裕幸,齋藤祐子,伊藤慎治,杉山美紀子,舟辺さやか,新井冨生,沢辺元司,金丸和富,石井賢二,宮下哲典,桑野良三,村山繁雄
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] Genetic deficiency of plasma lipoprotein phopsholipase A2(Lp-PLA2) and risk of Alzheimer's disease in Japan2010
- Author(s)
  Koshy B, Miyashita A, StJean P, Stirnadel H, Kaise T, Rubio J, Mooser V, Kuwano R, Irizarry M
- Organizer
  Alzheimer's Association International Conference 2010
- Place of Presentation
  Hawaii
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] Gene expression profiling of postmortem brain tissues with Alzheimer's disease.2010
- Author(s)
  Miyashita A, et al.
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2010
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] R. Gene expression profiling of postmortem brain tissues with Alzheimer's disease2010
- Author(s)
  Miyashita A, Saito Y, Hatsuta H, Tsukie T, Kakita A, Iijima R, Ogishima S, Tanaka H, Takahashi H, Murayama S, Ihara Y, Kuwano
- Organizer
  Alzheimer's Association International Conference 2010
- Place of Presentation
  Hawaii
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] The Japanese Genetic Study Consortium for Alzheimer's Disease(JGSCAD,代表:井原康夫).アルツハイマー病脳組織におけるSORL1の発現解析2010
- Author(s)
  温雅楠,宮下哲典,月江珠緒,齊藤祐子,初田裕幸,村山繁雄,柿田明美,高橋均,北村信隆,赤澤宏平,桑野良三
- Organizer
  第40回新潟神経学夏期セミナー
- Place of Presentation
  新潟
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-22790331
[Presentation] JGSCAD): Fine SNP mapping in and around the APOE in late-onset Alzheimer disease2009
- Author(s)
  Kuwano R, Takei N, Miyashita A, Ihara Y
- Organizer
  The 12th International Conference on Alzheimer's Disease
- Place of Presentation
  Vienna, Austria
- Year and Date
  2009-07-15
- Data Source
  KAKENHI-PROJECT-17020004
[Presentation] Gene Expression Profiling of Postmortem Brain Tissues Affected by Alzheimer's Disease2008
- Author(s)
  Miyashita A, Saitoh Y, Kakita A, Ogishima S, Tanaka H, Takahashi H, Murayama S, Ihara Y, Kuwano R
- Organizer
  The 11th International Conference on Alzheimer ' s Disease and Related Disorders
- Place of Presentation
  Chicago, USA
- Year and Date
  2008-07-29
- Data Source
  KAKENHI-PROJECT-17020004
[Presentation] 死後脳を用いた晩期発症型アルツハイマー病の網羅的遺伝子発現解析2008
- Author(s)
  宮下哲典
- Organizer
  第27回日本認知症学会
- Place of Presentation
  前橋市
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-17020004
[Presentation] Gene expression profiling of postmortem brain tissues affected by Alzheimer7s disease2008
- Author(s)
  Miyashita A.
- Organizer
  The 11th International Conference on Alzheimer's Disease and Related Disorder
- Place of Presentation
  シカゴ
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-17020004
[Presentation] Gender-related genetic lociassociated with late-onset Alzheimer's disease on chromosome 10q.2007
- Author(s)
  宮下哲典
- Organizer
  第26回日本認知症学会
- Place of Presentation
  大阪
- Year and Date
  2007-10-17
- Data Source
  KAKENHI-PROJECT-17020004
[Presentation] 染色体10番長腕におけるアルツハイマー病のリスク遺伝子2007
- Author(s)
  宮下哲典
- Organizer
  第52回日本人類遺伝学会
- Place of Presentation
  東京
- Year and Date
  2007-09-14
- Data Source
  KAKENHI-PROJECT-17020004
[Presentation] Genes associated with the progression of neurofibrillary tangles in Alzheimer’s disease brains
- Author(s)
  Miyashita A, Kuwano R, Hatsuta H, Kikuchi M, Nakaya A, Saito Y, Tsukie T, Hara N, Ogishima S, Kakita A, Takahashi H, Murayama S, Ihara, Ikeuchi T
- Organizer
  AAIC
- Place of Presentation
  Bella Center, Copenhagen, Denmark
- Year and Date
  2014-07-11 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-24310144
[Presentation] アルツハイマー病における生体分子間ネットワーク解析手法の提案
- Author(s)
  菊地正隆, 原範和, 宮下哲典, 初田裕幸, 齊藤祐子, 村山繁雄, 池内健, 桑野良三
- Organizer
  日本認知症学会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2014-11-27 – 2014-12-01
- Data Source
  KAKENHI-PROJECT-26640122
[Presentation] ヒト剖検脳を用いたアルツハイマー病関連マイクロRNAの解析.
- Author(s)
  原範和、菊地正隆、宮下哲典、初田裕幸、齊藤祐子、村山繁雄、赤津裕康、池内健、桑野良三
- Organizer
  日本認知症学会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2014-11-27 – 2014-12-01
- Data Source
  KAKENHI-PROJECT-26640122
[Presentation] 細胞特異的な遺伝子発現は染色体高次構造の影響を受けるのか？
- Author(s)
  菊地正隆, 長谷川舞衣, 原範和, 宮下哲典, 中谷明弘, 池内健, 桑野良三
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24310144
[Presentation] アルツハイマー病における生体分子間ネットワーク解析手法の提案
- Author(s)
  菊地正隆, 原範和, 宮下哲典, 初田裕幸, 齊藤祐子, 村山繁雄, 池内健, 桑野良三
- Organizer
  日本認知症学会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2014-11-27 – 2014-12-01
- Data Source
  KAKENHI-PROJECT-24310144
[Presentation] Genes associated with the progression of neurofibrillary tangles in Alzheimer’s disease brains
- Author(s)
  Miyashita A ほか
- Organizer
  AAIC
- Place of Presentation
  Bella Center, Copenhagen, Denmark
- Year and Date
  2014-07-11 – 2014-07-17
- Data Source
  KAKENHI-PLANNED-22129004
[Presentation] ヒト剖検脳を用いたアルツハイマー病関連マイクロRNAの解析.
- Author(s)
  原範和、菊地正隆、宮下哲典、初田裕幸、齊藤祐子、村山繁雄、赤津裕康、池内健、桑野良三
- Organizer
  日本認知症学会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2014-11-29 – 2014-12-01
- Data Source
  KAKENHI-PROJECT-24310144

1. KUWANO Ryozo (20111734)

# of Collaborated Projects: 9 results

# of Collaborated Products: 48 results
2. NAKAYA Akihiro (60301149)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
3. IKEUCHI Takeshi (20372469)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. AKAZAWA Kohei (10175771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. TOYABE Shin-ichi (20227648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. KAKITA Akiyoshi (80281012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. HASEGAWA Mai (50596153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. 橘正芳 (10128712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 他田真理 (30646394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 阿部学 (10334674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 荻島創一 (40447496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 川島秀一 (50314274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 片山俊明 (60396869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 鎌田真由美 (70749077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小島諒介 (70807651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 水野聖士 (80646795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 野中裕美

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KATSUNO Masahisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. TERADA Seishi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. IKEDA Yoshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 齊藤祐子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 村山繁雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 佐橋健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 井口洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 菊地正隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 横田修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 池田将樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 東海林幹夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Miyashita Akinori 宮下 哲典

宮下 哲典 ミヤシタ アキノリ

MIYASHITA Akinori 宮下 哲典

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Missense rare variant analysis of APOE: Exploring the link between lipid metabolism and Alzheimer's diseasePrincipal Investigator

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末梢血におけるアルツハイマー病脳関連遺伝子のエピジェネティック・遺伝子発現解析Principal Investigator

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Identification and expression analysis of genes controlled by a Alzheimer's disease susceptibility region including APOEPrincipal Investigator

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マウス胚性幹細胞を用いたジーントラップ法によるゲノム欠失型疾患モデルマウスの作出Principal Investigator

Miyashita Akinori 宮下哲典

宮下哲典ミヤシタアキノリ

MIYASHITA Akinori 宮下哲典