Hashii Yoshiko 橋井佳子

… Alternative Names

HASHII Yoshiko 橋井佳子

橋井佳子ハシイヨシコ

MATSUDA Yoshiko 松田佳子

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Researcher Number	60343258
Other IDs
Affiliation (Current)	2025: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 小児科主任部長
Affiliation (based on the past Project Information) *help	2021 – 2024: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 小児科主任部長 2018 – 2020: 大阪大学, 医学系研究科, 寄附講座准教授 2016 – 2017: 大阪大学, 医学系研究科, 講師 2012 – 2015: 大阪大学, 医学(系)研究科(研究院), 講師 2014: 大阪大学, 大学院医学系研究科, 講師 … More 2010 – 2012: 大阪大学, 医学系研究科, 講師 2005 – 2006: 大阪大学, 医学系研究科, 助手 2002 – 2003: 大阪大学, 医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Pediatrics / Basic Section 49030:Experimental pathology-related / Pediatrics
Keywords	Principal Investigator がんワクチン / WT1 / パイエル板 / ビフィズス菌 / 腸管免疫 / 樹状細胞 / LRRC8 / がん免疫 / 小児がん / 小児血液悪性腫瘍 … More / 同種造血幹細胞移植 / 癌ワクチン / 免疫細胞の動態 / KikGRマウス / 経口がんワクチン / WT1蛋白 / 癌免疫 / 腸内細菌 / B cell development / LRRC8 family / B細胞の分化 / LRRC8ファミリー / 小児血液腫瘍 / 免疫モニタリング / 同種移植後免疫療法 / 早期探索臨床試験 / 造血細胞移植 / 同種造血細胞移植 / ペプチドワクチン / 同種造血細胞移植後 / WT1ペプチドワクチン / 免疫療法 / 小児腫瘍学 … More Except Principal Investigator CD34+ CD38- / MCL-1 / IL-8 / 白血病幹細胞 / 単細胞遺伝子発現解析 / 細胞移動 / 細胞周期 / 細胞動態 / In situ光ラベリング / 急性骨髄性白血病 / immunology / biotechnology / gene / 免疫学 / バイオテクノロジー / 遺伝子 / DNA miroarray / hematopoietic stem cell / Leukemic stem cell / 幹細胞 / 白血病 / ABCG2 / マイクロアレイ / MONO-7 / CD34+CD38- / DNAマイクロアレイ / 造血幹細胞 / ゲノム編集技術 / がん免疫療法 / 免疫療法 / ゲノム編集 / がんワクチン療法 / ガン免疫療法 / iPS細胞 / 癌 / 細胞・組織 / 移植・再生医療 / TRAIL / 急性白血病 / 悪性腫瘍 / 小児 / 間葉系幹細胞 Less

Identification of novel therapeutic target molecules based on correlation between leukemia stem cell heterogeneity and in vivo dynamics
- Principal Investigator
  
  戸村道夫
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Osaka Ohtani University
腸管細胞の獲得免疫における動態評価Principal Investigator
- Principal Investigator
  
  橋井佳子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Osaka International Cancer Institute
Clarification of the mechanism of effectiveness of the oral cancer vaccine a platform expressing a cancer antigenPrincipal Investigator
- Principal Investigator
  
  Hashii Yoshiko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Development new immunotherapy for pediatric cancer using human iPSCs
- Principal Investigator
  
  Miyamura Takako
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Elucidation and control of molecular mechanism in WT1 peptide vaccine therapy after allogeneic hematopoietic stem cell transplantationPrincipal Investigator
- Principal Investigator
  
  Hashii Yoshiko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
The preferential anticancer effect on pediatric malignancies by mesencymal stem cells
- Principal Investigator
  
  MIYAMURA Takako
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
  Okayama University
Development of WT1 based immunotherapy after stem cell transplantation and the analysis of antitumor activityPrincipal Investigator
- Principal Investigator
  
  HASHII Yoshiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Functional analysis of gene LRRC8 causing agammaglobulinemia
- Principal Investigator
  
  OHTA Hideaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Functional characterization of LRRC8, a novel gene isolated from a patients with agammaglobulinemia, and its homologues.Principal Investigator
- Principal Investigator
  
  HARA Junichi, 松田佳子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Detection and characterization of leukemic stem cells
- Principal Investigator
  
  HARA Junichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University

[Journal Article] Enhanced antitumor activity of a novel, oral, helper epitope-containing WT1 protein vaccine in a model of murine leukemia2023
- Author(s)
  Minagawa Hikaru、Hashii Yoshiko、Nakajima Hiroko、Fujiki Fumihiro、Morimoto Soyoko、Nakata Jun、Shirakawa Toshiro、Katayama Takane、Tsuboi Akihiro、Ozono Keiichi
- Journal Title
  
  BMC Cancer
  
  Volume: 23 Issue: 1 Pages: 167-167
- DOI
  10.1186/s12885-023-10547-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07841, KAKENHI-PROJECT-23K06761
[Journal Article] An oral WT1 protein vaccine composed of WT1-anchored, genetically engineered Bifidobacterium longum allows for intestinal immunity in mice with acute myeloid leukemia.2022
- Author(s)
  1.Nakagawa N, Hashii Y, Kayama H, OkumuraR, Nakajima H, Minagawa H, Morimoto S, Fujiki F, Nakata J, Shirakawa T, Katayama T, Takeda K, Tsuboi A, Ozono K.
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07841
[Journal Article] An oral WT1 protein vaccine composed of WT1-anchored, genetically engineered Bifidobacterium longum allows for intestinal immunity in mice with acute myeloid leukemia2022
- Author(s)
  Nakagawa Natsuki、Hashii Yoshiko、Kayama Hisako、Okumura Ryu、Nakajima Hiroko、Minagawa Hikaru、Morimoto Soyoko、Fujiki Fumihiro、Nakata Jun、Shirakawa Toshiro、Katayama Takane、Takeda Kiyoshi、Tsuboi Akihiro、Ozono Keiichi
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 72 Issue: 1 Pages: 39-53
- DOI
  10.1007/s00262-022-03214-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07841, KAKENHI-PROJECT-23K06761
[Journal Article] 小児がん治療の晩期合併症を回避するために～免疫療法の確立2020
- Author(s)
  橋井佳子
- Journal Title
  
  Bio Clinica
  
  Volume: 35 Pages: 145-150
- Data Source
  KAKENHI-PROJECT-17K10109
[Journal Article] 小児がん治療の晩期合併症を回避するために　免疫療法の開発2020
- Author(s)
  橋井佳子
- Journal Title
  
  BIO Clinica
  
  Volume: 35 Pages: 145-150
- Data Source
  KAKENHI-PROJECT-17K10109
[Journal Article] WT1蛋白を標的とした新規免疫療法の開発ペプチドワクチンから人体最大の免疫組織　腸管をいかした経口がんワクチンへ2020
- Author(s)
  橋井佳子
- Journal Title
  
  Precision Medicine
  
  Volume: 3 Pages: 80-85
- Data Source
  KAKENHI-PROJECT-17K10109
[Journal Article] 小児がんに対するWT1蛋白を標的とした免疫療法の開発　ペプチドワクチンから経口がんワクチンへ2019
- Author(s)
  橋井佳子
- Journal Title
  
  BIO Clinica
  
  Volume: 34 Pages: 969-974
- Data Source
  KAKENHI-PROJECT-17K10109
[Journal Article] Perioperative management after high-dose chemotherapy with autologous or allogeneic hematopoietic stem cell transplantation for pediatric solid tumors2015
- Author(s)
  Uehara S, Oue T, Nakahata K, Nara K, Ueno T, Owari M, Usui N, Miyamura T, Hashii Y
- Journal Title
  
  European Journal of Pediatric Surgery
  
  Volume: 25 Issue: 01 Pages: 118-122
- DOI
  10.1055/s-0034-1386638
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23256006, KAKENHI-PROJECT-23591541
[Journal Article] Mycobacterium avium complex-associated peritonitis with CAPD after unrelated bone marrow transplantation.2014
- Author(s)
  Miyashita E, Yoshida H, Mori D, Nakagawa N, Miyamura T, Ohta H, Seki M, Tomono K, Hashii Y, Ozono K
- Journal Title
  
  Pediatr Int
  
  Volume: 56(6) Issue: 6
- DOI
  10.1111/ped.12463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591541, KAKENHI-PROJECT-24406022
[Journal Article] 小児がんに対する WT1 ペプチドワクチン治療2014
- Author(s)
  橋井佳子
- Journal Title
  
  日本小児血液がん学会雑誌
  
  Volume: 51 Pages: 412-417
- Data Source
  KAKENHI-PROJECT-25461592
[Journal Article] WT1 peptide vaccination following allogeneic stem cell transplantation in pediatric leukemic patients with high risk for relapse: successful maintenance of durable remission2012
- Author(s)
  Hashii Y, Sato-Miyashita E, Matsumura R, Kusuki S, Yoshida H, Ohta H, Hosen N, Tsuboi A, Oji Y, Oka Y, Sugiyama H, Ozono K
- Journal Title
  
  Leukemia
  
  Volume: 26 Pages: 530-532
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] WT1 peptide vaccination following allogeneic stem cell transplantation in pediatric leukemic patients with high risk for relapse : successful maintenance of durable remission2012
- Author(s)
  Hashii Y, Sato-Miyashita E, Matsumura R, Kusuki S, Yoshida H, Ohta H, Hosen N, Tsuboi A, Oji Y, Oka Y, Sugiyama H, Ozono K.
- Journal Title
  
  Leukemia
  
  Volume: 26 Issue: 3 Pages: 530-2
- DOI
  10.1038/leu.2011.226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591205, KAKENHI-PROJECT-22591160
[Journal Article] 同種造血幹細胞移植後の難治性小児血液腫瘍患者におけるWT1ペプチドワクチンを用いた免疫療法2011
- Author(s)
  橋井佳子、松村梨沙、吉田寿雄、宮下恵実子、太田秀明、坪井昭博、尾路祐介、保仙直毅、岡芳弘、大薗恵一、杉山治夫
- Journal Title
  
  Biotherapy
  
  Volume: 25 Pages: 851-856
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] 悪性腫瘍に対するWT1ペプチドワクチン療法-特に2011
- Author(s)
  Oka Y, Tsuboi A, Nishida S, Hosen N, Nakata J, Hashii Y, Maeda T, Oji Y, Kumanogoh A, Sugiyama H
- Journal Title
  
  造血器腫瘍に焦点を当て
  
  Volume: 52 Pages: 235-242
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] 同種造血幹細胞移植後の難治性小児血液腫瘍患者におけるWT1ペプチドワクチンを用いた免疫療法2011
- Author(s)
  橋井佳子, ほか
- Journal Title
  
  バイオセラピイ
  
  Volume: 25 Pages: 851-856
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] 小児がんに対するWT1ペプチドワクチン療法2010
- Author(s)
  太田秀明、橋井佳子
- Journal Title
  
  小児がん
  
  Volume: 47 Pages: 263-267
- NAID
  110007671760
- Data Source
  KAKENHI-PROJECT-22591160
[Journal Article] LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins2004
- Author(s)
  Keiko K, Matsuda-Hashii Y, Hara J, et al.
- Journal Title
  
  FEBS Letters 564(1-2)
  
  Pages: 147-152
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591105
[Journal Article] LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins2004
- Author(s)
  Kubota K, Kim JY, Sawada A, Tokimasa S, Fujisaki H, Matsuda-Hashii Y, Ozano K, Hara J.
- Journal Title
  
  FEBS Letters 564(1-2)
  
  Pages: 147-152
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591105
[Journal Article] A congenital mutation of the novel gene LRRC8 causes agammaglobuloinemia in humans2003
- Author(s)
  Sawada A, Matsuda-Hashii Y, Hara J, et al.
- Journal Title
  
  J Clin Incest 112(11)
  
  Pages: 1707-1713
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591105
[Journal Article] A congenital mutation of the novel gene LRRC8 causes agammaglobulinemia in humans2003
- Author(s)
  Sawada A, Takihara Y, Kim JY, Matsuda-Hashii Y, Tokimasa S, Fujisaki H, Kubota K, Endo H, Onodera T, Ohta H, Ozono K, Hara J.
- Journal Title
  
  J Clin Incest. 112(11)
  
  Pages: 1707-1713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591105
[Journal Article] Establishment of a monosomy 7 leukemia cell line, MONO-7, with a ras gene mutation.2002
- Author(s)
  Fujisaki H, Takai, K.Akihisa, S.Tokimasa, S.Matsuda, Y.Ohta, H Osugi, Y.Kim, J.Sako M.Hara, J.
- Journal Title
  
  Int J Hematol 75
  
  Pages: 72-77
- NAID
  10007867337
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570743
[Journal Article] Establishment of a monosomy 7 leukemia cell line, MONO-7, with a ras gene mutation.2002
- Author(s)
  Fujisaki, H., Takai, K., Akihisa, S., Tokimasa, S., Matsuda, Y., Ohta, H., Osugi, Y., Kim, J.Y., Sako, M., Hara, J.
- Journal Title
  
  Int J Hematol 75
  
  Pages: 72-77
- NAID
  10007867337
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570743
[Patent] 経口腫瘍ワクチン2020
- Inventor(s)
  橋井佳子、大薗恵一、白川利朗、片山高嶺
- Industrial Property Rights Holder
  橋井佳子、大薗恵一、白川利朗、片山高嶺
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-17K10109
[Patent] 経口腫瘍ワクチンと免疫抑制阻害剤との併用によるがん治療2018
- Inventor(s)
  橋井佳子、白川利朗、片山高嶺
- Industrial Property Rights Holder
  橋井佳子、白川利朗、片山高嶺
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-558975
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K10109
[Patent] 経口腫瘍ワクチンと免疫抑制阻害剤との併用によるがん治療2017
- Inventor(s)
  白川利朗、橋井佳子
- Industrial Property Rights Holder
  白川利朗、橋井佳子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-558975
- Filing Date
  2017
- Acquisition Date
  2020
- Data Source
  KAKENHI-PROJECT-17K10109
[Presentation] An oral WT1 protein vaccine composed of WT1-anchored, genetically engineered Bifidobacterium longum activates intestinal immunity and exhibits anti-tumour effects in mice with acute myeloid leukemia.2023
- Author(s)
  橋井佳子
- Organizer
  10th International Conference on WT1 in Human Neoplasia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07841
[Presentation] WT1蛋白を標的とした小児固形腫瘍に対するがん免疫療法　予後と免疫学的解析2022
- Author(s)
  橋井佳子
- Organizer
  日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-21K07841
[Presentation] 小児がんに対する免疫療法の現状　小児固形腫瘍に対するWT1ペプチドワクチン療法の有効性と免疫学的解析2022
- Author(s)
  橋井佳子
- Organizer
  日本がん治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07841
[Presentation] WT1蛋白を標的としたがんワクチン治療の現状とあらたな展開2020
- Author(s)
  橋井佳子
- Organizer
  日本小児科学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10109
[Presentation] WT1-targeteing immunotherapy in children with refractory cancer2020
- Author(s)
  橋井佳子
- Organizer
  日本小児血液がん学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10109
[Presentation] The anti-tumor effect of oral cancer vaccine using Bifidobacterium as a platform for displaying Wilms’ tumor 1 protein.2019
- Author(s)
  Hikaru Minagawa, Yoshiko Hashii, Natsuki Nakagawa, Hiroko Nakajima, Yoshihiro Oka, Takane Katayama, Toshiro Shirakawa, Keiichi Ozono
- Organizer
  2019 ASCO-SITC Clinical Immuno-Oncology Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10109
[Presentation] Immunotherapy Targeting Wilms’ Tumor 1 for Pediatric Cancer2016
- Author(s)
  Hashii Yoshiko
- Organizer
  Korean Society of Pediatric Hematology-Oncology
- Place of Presentation
  Seoul, Korea,
- Year and Date
  2016-10-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 小児がんにおける免疫療法の現状と今後の展望～免疫制御抗体の先を見据えて～2015
- Author(s)
  橋井佳子
- Organizer
  第57回日本小児血液・がん学会学術集会
- Place of Presentation
  甲府富士屋ホテル
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 小児がんに対するWT1ペプチドワクチンを用いた免疫療法:新しい集学的治療の開発2015
- Author(s)
  橋井佳子
- Organizer
  第53回日本癌治療学会
- Place of Presentation
  国立京都国際会議場
- Year and Date
  2015-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] WT1vaccination for pediatric malignancies.2015
- Author(s)
  Yoshiko Hashii
- Organizer
  First Sino-US-Japan Pediatric Translational Medicine Forum and Third International Pediatric Hematology and Oncology
- Place of Presentation
  Songshan Hall and Tiansha Hall(China)
- Year and Date
  2015-11-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] WT1ワクチンを用いた難治性小児血液腫瘍患者に対する同種移植後免疫療法　臨床試験：再発例の解析2015
- Author(s)
  橋井佳子
- Organizer
  第7回血液疾患免疫療法研究会
- Place of Presentation
  東京大学　伊藤謝恩ホール
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] Phase I/II clinical study of WT1 peptide vaccination in pediatric leukemia patients after allogeneic stem cell transplantation2015
- Author(s)
  Yoshiko Hashii
- Organizer
  The 8th International Conference on WT1 in Human Neoplasia
- Place of Presentation
  KBS Kyoto Hall
- Year and Date
  2015-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 骨転移に対して手術、放射線治療を施行した難治性肝芽腫の1例.2015
- Author(s)
  宮村能子，橋井佳子，濱田健一郎，中　紀文，吉田寿雄，宮下恵実子，齋藤広幸，磯橋文明，上原秀一郎，大植孝治，奥山宏臣，大薗恵一.
- Organizer
  日本小児肝癌スタディグループ(JPLT)研究会
- Place of Presentation
  東京
- Year and Date
  2015-01-25
- Data Source
  KAKENHI-PROJECT-23591541
[Presentation] 小児WT1ペプチドワクチン臨床試験　事務局報告2015
- Author(s)
  橋井佳子
- Organizer
  第18回WT1ペプチド癌免疫療法研究会
- Place of Presentation
  大阪
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] WT1蛋白を標的とした小児白血病への免疫療法2014
- Author(s)
  橋井佳子
- Organizer
  第18回大阪小児免疫研究会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] WTワクチンを用いた難治性小児血液腫瘍患者に対する同種移植後免疫療法臨床試験：中間報告2014
- Author(s)
  橋井佳子
- Organizer
  第6回血液疾患免疫療法研究会
- Place of Presentation
  京都
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 小児白血病に対する免疫療法：がんワクチンはこどもの“未来”を作るくすりです2014
- Author(s)
  橋井佳子
- Organizer
  第16回さくら造血細胞セミナー
- Place of Presentation
  東京
- Year and Date
  2014-11-13
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] WT1ペプチドワクチンを用いた小児悪性固形腫瘍に対する第I/II相臨床試験2013
- Author(s)
  橋井　佳子
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 小児血液腫瘍に対する同種造血幹細胞移植後WT1ペプチドワクチンの有効性2013
- Author(s)
  橋井佳子
- Organizer
  第16回WT1ペプチド癌免疫療法研究会
- Place of Presentation
  大阪大学
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 小児血液腫瘍に対する同種造血幹細胞移植後WT1ペプチドワクチンの有効性2013
- Author(s)
  橋井佳子
- Organizer
  第16回WT1ペプチド癌免疫療法研究会
- Place of Presentation
  大阪
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1ペプチドワクチンを用いた難治性小児血液腫瘍患者にに対する同種造血幹細胞移植後免疫療法第II相試験2013
- Author(s)
  橋井　佳子
- Organizer
  第5回造血器腫瘍免疫療法研究会
- Place of Presentation
  ウイング愛知
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] Tumor immunotherapy targeting WT1 (Wilms tumor gene 1) peptide for pediatric rare tumors.2013
- Author(s)
  Yoshiko Hashii
- Organizer
  45th Congress of the International Society of Paediatric Oncology
- Place of Presentation
  Hong Kong China
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 同種造血幹細胞移植後のWT1ペプチドワクチンによる小児血液悪性腫瘍に対する免疫療法2013
- Author(s)
  橋井　佳子
- Organizer
  第26回日本バイオセラピィ学会学術集会
- Place of Presentation
  いわて県民情報交流センター　アイーナ
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 小児科における血液腫瘍・免疫の役割　　～悪性腫瘍、感染症治療戦略と免疫治療について～2013
- Author(s)
  橋井佳子
- Organizer
  第21回高知県小児神経疾患研究会
- Place of Presentation
  ザ・クラウンパレス新阪急
- Invited
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] こどもの治る力を引き出す治療～WT1ぺプチドワクチン療法2013
- Author(s)
  橋井　佳子
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク
- Invited
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 再発高悪性グリオーマに対するWT1ペプチドワクチンを用いた免疫療法2013
- Author(s)
  橋井　佳子
- Organizer
  第12回小児脳腫瘍治療研究会
- Place of Presentation
  帝人ビル
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 小児がんに対するWT1ペプチドワクチン療法2013
- Author(s)
  橋井　佳子
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 子どものなおる力を引き出す治療：WT1ワクチン療法2013
- Author(s)
  橋井　佳子
- Organizer
  第3回東京小児がん研究セミナー
- Place of Presentation
  ベルサーチ八重洲
- Invited
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 小児白血病を「本当に治る病気」にするために2013
- Author(s)
  橋井　佳子
- Organizer
  第19回九州山口小児血液・腫瘍研究会
- Place of Presentation
  九州大学コラボステーションI
- Invited
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] Clinical effects of Wilms Tumor Protein(WT)1 peptide vaccination in pediatric patiens with Rhabdomyosarcoma.2013
- Author(s)
  Yoshiko Hashii
- Organizer
  45th Congress of the International Society of Paediatric Oncology
- Place of Presentation
  Hong Kong China
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] Clinical of WT1 peptide vaccination for pediatric leukemia after stem cell transplantation.2013
- Author(s)
  橋井　佳子
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] WT1 peptide vaccination following allogeneic stem cell transplantation2012
- Author(s)
  橋井佳子
- Organizer
  The　6th International Conference on WT1 in Human neoplasma　in pediatric patients
- Place of Presentation
  京都KBSホール
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 当院でのRIST+免疫療法をおこない寛解維持している寛解導入遅延例2012
- Author(s)
  橋井佳子
- Organizer
  JPLSG総会
- Place of Presentation
  国立病院機構名古屋医療センター
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 小児血液悪性腫瘍を対象とした同種造血幹細胞移植後のWT1ワクチン療法2012
- Author(s)
  橋井佳子、大薗恵一
- Organizer
  第15回WT1ペプチド癌免疫治療研究会
- Place of Presentation
  大阪
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1ペプチドワクチンを用いた小児血液腫瘍に対する同種造血幹細胞移植後免疫療法.2012
- Author(s)
  橋井佳子、宮村能子、松村梨紗、吉田寿雄、宮下恵実子、平松英文、谷澤昭彦、坪井昭博、尾路祐介、保仙直毅、岡芳弘、杉山治夫、.大薗恵一
- Organizer
  第4回造血器腫瘍免疫療法研究会学術総会
- Place of Presentation
  金沢
- Year and Date
  2012-08-18
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1ペプチドワクチンを用いた小児血液腫瘍に対する同種造血幹細胞移植後免疫療法2012
- Author(s)
  橋井佳子
- Organizer
  造血器腫瘍免疫療法研究会
- Place of Presentation
  金沢市文化ホール
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1ペプチドワクチンを用いた小児血液腫瘍に対する同種造血幹細胞移植後免疫療法2012
- Author(s)
  橋井佳子
- Organizer
  日本血液学会
- Place of Presentation
  国立京都国際会議場
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 同種造血幹細胞移植後のWT1ペプチドワクチンによる免疫療法2011
- Author(s)
  橋井佳子
- Organizer
  第14回WT1ペプチドがん免疫療法研究会
- Place of Presentation
  大阪
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1ペプチドワクチンを用いた小児血液腫瘍に対する同種造血幹細胞移植後免疫療法2011
- Author(s)
  橋井佳子
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1ペプチドワクチンを用いた小児血液腫瘍に対する同種造血幹細胞移植後免疫療法2011
- Author(s)
  橋井佳子
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 同種造血幹細胞移植後のWT1ペプチドワクチンによる免疫療法2011
- Author(s)
  橋井佳子
- Organizer
  第3回造血器腫瘍免疫治療研究会
- Place of Presentation
  別府
- Year and Date
  2011-08-21
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 同種造血幹細胞移植後のWT1ペプチドワクチンによる免疫療法2011
- Author(s)
  橋井佳子
- Organizer
  第14回WT1ペプチドがん免疫療法研究会
- Place of Presentation
  大阪府吹田市大阪大学
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 同種造血幹細胞移植後のWT1ペプチドワクチンによる免疫療法2011
- Author(s)
  橋井佳子
- Organizer
  第3回造血器腫瘍免疫療法研究会
- Place of Presentation
  大分県別府市ホテル白菊
- Year and Date
  2011-08-21
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 同種造血幹細胞移植後の難治性小児血液腫瘍患者に対するWT1ペプチドワクチンを用いた免疫療法2010
- Author(s)
  橋井佳子
- Organizer
  第2回造血器腫瘍免疫治療研究会
- Place of Presentation
  松山
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 同種造血幹細胞移植後の難治性小児血液腫瘍患者に対するWT1ペプチドワクチンを用いた免疫療法2010
- Author(s)
  橋井佳子
- Organizer
  日本バイオセラピイ学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 同種造血幹細胞移植後の難治性小児血液腫瘍患者に対するWT1ペプチドワクチヒンを用いた免疫療法2010
- Author(s)
  橋井佳子
- Organizer
  造血器腫瘍免疫療法研究会
- Place of Presentation
  大和屋本店
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1ペプチドワクチンによる再発させない小児がん治療2010
- Author(s)
  橋井佳子
- Organizer
  第48回日本癌治療学会
- Place of Presentation
  国立京都国際会議場.
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 同種造血幹細胞移植後の難治性小児血液腫瘍患者に対する WT1 ペプチドワクチンを用いた免疫療法2010
- Author(s)
  橋井佳子、太田秀明、松村梨沙、吉田寿雄、楠木重範、佐藤恵実子、坪井昭博、尾路祐介、岡芳弘、杉山治夫、大薗恵一
- Organizer
  第52回日本小児血液学会
- Place of Presentation
  大阪
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] WT1ペプチドワクチンによる再発させない小児がん治療2010
- Author(s)
  橋井佳子
- Organizer
  日本癌治療学会
- Place of Presentation
  国立京都国際会館(招待講演)
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 小児血液腫瘍に対する同種造血幹細胞移植後のWT1ペプチドワクチン療法2010
- Author(s)
  橋井佳子、松村梨沙、吉田寿雄、楠木重範、佐藤恵実子、太田秀明、大薗恵一
- Organizer
  第12回WT1ペプチドがん免疫療法研究会
- Place of Presentation
  大阪
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] 同種造血幹細胞移植後の難治性小児血液腫瘍患者に対するWT1ペプチドワクチンを用いた免疫療法2010
- Author(s)
  橋井佳子
- Organizer
  日本バイオセラピイ学会
- Place of Presentation
  大阪国際会議場.
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22591160
[Presentation] Phase II clinical study of WT1 peptide vaccination in pediatric leukemia patients after allogeneic stem cell transplantation – clinical efficacy and immunological monitoring
- Author(s)
  Yoshiko Hashii
- Organizer
  American Society of Hematology
- Place of Presentation
  San Francisco　USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] WT1ペプチドワクチンを用いた小児血液腫瘍に対する移植後免疫療法第 I/II相臨床試験
- Author(s)
  橋井佳子
- Organizer
  日本血液学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25461592
[Presentation] 大量化学療法後にウイルス関連出血性膀胱炎を合併した神経芽細胞腫の2例.
- Author(s)
  宮村能子，橋井佳子，吉田寿雄，宮下恵実子，中川夏季，齊藤広幸，上原秀一郎，大植孝治，大薗恵一.
- Organizer
  第56回日本小児血液・がん学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-23591541
[Presentation] Clinical characteristic and prognosis of post-transplant lymphoproliferative disorder: A single institute experience in Japan.
- Author(s)
  Miyamura T，Hashii Y， Fukushima N， Kogaki S，Minami M， Ueno T，Kondo H，Yoshida H， Miyashita E，Nakagaw N， Saito H， Ozono K.
- Organizer
  46th Congress of the International society of Paediatric Oncology
- Place of Presentation
  Toronto,Canada.
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-23591541
[Presentation] 移植後リンパ増殖性疾患(PTLD)の臨床経過と予後についての検討.
- Author(s)
  宮村能子，橋井佳子，福島教偉，小垣滋豊，南　正人，上野豪久，近藤宏樹，吉田寿雄，宮下恵美子，大薗恵一.
- Organizer
  第50回日本移植学会総会
- Place of Presentation
  東京
- Year and Date
  2014-09-10 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-23591541
[Presentation] 化学療法を変更し治療効果が得られた初期治療抵抗性Wilms腫瘍の1例.
- Author(s)
  宮村能子，橋井佳子，吉田寿雄，宮下恵実子，中川夏季，齊藤広幸，上原秀一郎，大植孝治，大薗恵一.
- Organizer
  第56回日本小児血液・がん学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-23591541

1. OHTA Hideaki (60322187)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. MIYAMURA Takako (20379796)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. HARA Junichi (00238156)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. OKA Yoshihiro (20273691)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. TOKIMASA Sadao (80403187)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 白川利朗 (70335446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. 片山高嶺 (70346104)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. 戸村道夫 (30314321)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. FUJISAKI Hiroyuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. MIYASHITA Emiko (40528395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. NANBA Noriyuki (10379076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YAMASHITA Nobuko (40379798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. WASHIO Kana (10379802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 北畠康司 (80506494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 香山尚子 (40548814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 皆川光 (60792132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 楠本豊 (40252689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 橋本茉由子 (60943628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 岩崎正幸 (70790913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 大植孝治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 尾路祐介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashii Yoshiko 橋井 佳子

HASHII Yoshiko 橋井 佳子

橋井 佳子 ハシイ ヨシコ

MATSUDA Yoshiko 松田 佳子

Research Projects

Research Products

Co-Researchers

Identification of novel therapeutic target molecules based on correlation between leukemia stem cell heterogeneity and in vivo dynamics

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腸管細胞の獲得免疫における動態評価Principal Investigator

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Clarification of the mechanism of effectiveness of the oral cancer vaccine a platform expressing a cancer antigenPrincipal Investigator

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Development new immunotherapy for pediatric cancer using human iPSCs

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Elucidation and control of molecular mechanism in WT1 peptide vaccine therapy after allogeneic hematopoietic stem cell transplantationPrincipal Investigator

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The preferential anticancer effect on pediatric malignancies by mesencymal stem cells

Principal Investigator

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Development of WT1 based immunotherapy after stem cell transplantation and the analysis of antitumor activityPrincipal Investigator

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Functional analysis of gene LRRC8 causing agammaglobulinemia

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Functional characterization of LRRC8, a novel gene isolated from a patients with agammaglobulinemia, and its homologues.Principal Investigator

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Detection and characterization of leukemic stem cells

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[Journal Article] Enhanced antitumor activity of a novel, oral, helper epitope-containing WT1 protein vaccine in a model of murine leukemia2023

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[Journal Article] An oral WT1 protein vaccine composed of WT1-anchored, genetically engineered Bifidobacterium longum allows for intestinal immunity in mice with acute myeloid leukemia.2022

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[Journal Article] An oral WT1 protein vaccine composed of WT1-anchored, genetically engineered Bifidobacterium longum allows for intestinal immunity in mice with acute myeloid leukemia2022

Author(s)

Journal Title

DOI

Hashii Yoshiko 橋井佳子

HASHII Yoshiko 橋井佳子

橋井佳子ハシイヨシコ

MATSUDA Yoshiko 松田佳子

[Journal Article] 小児がん治療の晩期合併症を回避するために　免疫療法の開発2020

[Journal Article] WT1蛋白を標的とした新規免疫療法の開発ペプチドワクチンから人体最大の免疫組織　腸管をいかした経口がんワクチンへ2020

[Journal Article] 小児がんに対するWT1蛋白を標的とした免疫療法の開発　ペプチドワクチンから経口がんワクチンへ2019