Kubo Makoto 久保真

… Alternative Names

KUBO Makoto 久保真

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Researcher Number	60403961
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 九州大学, 医学研究院, 准教授 2016 – 2021: 九州大学, 大学病院, 講師 2007 – 2016: Kyushu University, University Hospital, Assistant Professor 2010: 九州大学, 大學病院, 助教 2005 – 2007: 九州大学, 大学病院, 助手
Review Section/Research Field	Principal Investigator General surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator General surgery / Digestive surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55020:Digestive surgery-related / Basic Section 53020:Cardiology-related
Keywords	Principal Investigator CD44+24- / 乳癌 / ネオアンチゲン / low cell / side population / cancer stem cell / 形態形成シグナル / 薬剤耐性 / 腫瘍浸潤リンパ球（TIL） / MHCテトラマー解析 … More / 細胞医薬 / TIL / ペプチド / 体細胞性遺伝子変異 / ペプチドがんワクチン療法 / Tumor mutational burden / 免疫チェックポイント阻害薬 / がんゲノム / 腫瘍浸潤リンパ球 / 腫瘍遺伝子変異量 / 腫瘍免疫 / がん微小環境 / estroren receptor / morphogenesis signais / anticancer-drug resistant / breast cancer / エストロゲン・レセプター / BRCA1ness / 浸潤性乳菅癌 / Notch経路 / BRCAness / Basal-like / Stemness / Notch4 / Notchシグナル経路 / トリプルネガティブ乳癌 / low細胞 / Side population / 腫瘍幹細胞療法 / リンパ節転移 / CD44+/CD24-細胞 / Hedgehogシグナル系 / Cancer stem cell … More Except Principal Investigator 膵癌 / Hedgehogシグナル / 乳癌 / 乳がん / 治療標的 / 増殖能 / 浸潤能 / オルガノイド / 癌微小環境 / 膵星細胞 / 抗腫瘍効果 / 癌免疫療法 / 癌浸潤リンパ球 / バイオマーカー / MAML3 / RBPJ / 悪性形質誘導 / 低酸素環境 / ヘッジホッグシグナル / 免疫療法 / 増殖 / 制御性T細胞 / 低酸素 / 膵がん / 浸潤 / 分子標的治療 / 大腸癌 / シグナルクロストーク / ALIオルガノイド / 腫瘍微小環境 / 癌免疫微小環境 / 腫瘍内不均一性 / シングルセル解析 / scRNA-seq / scRNAseq / 腫瘍免疫微小環境 / 治療抵抗性 / 癌免疫治療 / Hedgehogシグナル阻害剤 / 乳癌線維化 / 硬癌 / 新規癌治療法開発 / リンパ球組織浸潤 / スキルスタイプ / 細胞傷害性リンパ球 / 腫瘍浸潤リンパ球 / 癌線維化 / 微小環境因子 / desmoplasia / PDXマウス / テーラーメイド治療 / Pin1 / 化合物ライブラリー / 癌間質相互作用 / ハイスループットスクリーニング / Niche factors / CAF / 膵癌肝転移 / 腸内細菌叢 / 新規膵癌治療薬 / 新規癌治療薬 / ERAP2 / 新規治療薬 / 隔離膜 / 小胞体 / オートファジー / 次世代シーケンシング / 個別化治療 / 病理診断 / 人工知能による深層機械学習システム / 個別化医療 / 免疫染色 / 人工知能 / 循環器内科学 / ゲノム / ゲノム遺伝子 / コピー数多型 / 遺伝子多型 / 予測因子 / 一塩基多様性 / 挿入欠失配列 / ゲノム変異 / 心毒性 / トラスツズマブ / Hedgehog signal / Liprin alpha4 / C4orf47 / 膵癌悪性化 / 癌悪性形質 / 治療薬創生 / hedgehogシグナル / SMO / 免疫細胞療法 / ランダムマイグレーション / 細胞障害活性 / 運動能 / リンパ球増殖能 / 細胞傷害活性 / 治療効果予測 / リンパ球運動能 / 活性化リンパ球 / Theranv for colorectal cancer / Glil mRNA / Morphogenesis signaling Pathways / Hedgehog signaling pathway / Wnt signaling pathway / Colorectal cancer / Glil遺伝子 / 大腸がん治療 / Gli1遺伝子 / 形態形成シグナル / Wntシグナル / 大腸がん / Intercellular transmission / Vaccine therapy / Artificial antigens / Functional molecules / Gene transfer / Exosomes / Breast cancer / 伝達物質 / 遺伝子治療 / 細胞間伝達 / ワクチン療法 / 人工抗原 / 機能分子 / 遺伝子導入 / エキソゾーム / 膵臓癌 / Notchシグナル / Ｓｍｏｏｔｈｅｎｅｄ転写活性 / 新規治療標的 / smo転写活性 / 新規治療法開発 / 癌予防法開発 / Smoothened転写 / 膵癌浸潤 / 膵癌増殖 / 膵癌悪性形質 / 転写活性化亢進 / 転写活性 / Smoothened / Hedgehog経路 / Estrogen receptor経路 / エストロゲンレセプターシグナル / 腫瘍形成能 / CD24分子 / 包括的乳癌治療法 / 癌幹細胞 / エストロゲンレセプター / 免疫制御 / 予後予測因子 / 胸腺 / リンパ節 / 大腸癌組織 / アバスチン / FOXP3 / Treg細胞 / 予後因子 / 遊走 / 腫瘍内集積 / VEGF / VEGFR2 / 予防治療 / 前癌病変 / Smo / リンパ節転移 / 乳癌進展 / 包括的癌治療 / 前立腺がん / 免疫不全マウス / 治療標的分子 / 腫瘍幹細胞 / 胃癌 / Gli1 / 薬剤耐性 / 特異的 / γ-secretase / M集積 / G2 / Notch / g-secretase / 細胞増殖 / Nicastrin / Presenilin-2 / Presenilin-1 / ガンマセクレターゼ複合体 / 細胞周期 / アポトーシス / Taxane / GS 阻害剤 / gamma secretase (GS)複合体 / シグナル・クロストーク / Sonic Hh(Shh) / ER経路 / Hedgehog(Hh)シグナル / 治療 / 増殖抑制 / クロストーク / シグナ / Sonic hedgehog / ERα経路 Less

Development of a cancer fibrosis inhibition immunotherapy in breast cancer using Hedgehog signaling inhibitor
- Principal Investigator
  
  OYAMA Yasuhiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
Analysis and remodeling of immune microenvironment using pancreatic cancer organoids after treatment
- Principal Investigator
  
  NAKAMURA Masafumi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyushu University
Development of therapy-resistant breast cancer treatment using neoantigen-reactive lymphocytesPrincipal Investigator
- Principal Investigator
  
  KUBO Makoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyushu University
Construction of Breast Cancer Tissue Image Analysis Algorithm Using Deep Machine Learning System with Artificial Intelligence
- Principal Investigator
  
  KAI Masaya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University
The origin of autophagosome derived from the endoplasmic reticulum with a focus on pancreatic stellate cell activation genes
- Principal Investigator
  
  SAKAI Hiroshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
Elucidation of the mechanism of pancreatic cancer-induced dysbiosis and establishment of liver metastasis
- Principal Investigator
  
  KOZONO Shingo
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyushu University
Construction of an anticancer drug screening system using human pancreatic cancer tissue and therapeutic application
- Principal Investigator
  
  KOZONO Shingo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyushu University
Genetic polymorphisms predict development of trastuzumab-induced cardiotoxicity
- Principal Investigator
  
  Kisho Ohtani
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyushu University
Neoantigen analysis in tumor tissues for development of personalized precision cancer immunotherapyPrincipal Investigator
- Principal Investigator
  
  KUBO Makoto
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
Analysis of hypoxia-induced RBPJ/MAML3-SMO activation pathway and development of therapeutic strategy against pancreatic cancer
- Principal Investigator
  
  Onishi Hideya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Analysis of the mechanism of augmentation of random migration in lymphocytes and verification of the significance as a biomarker predicting therapeutic effect of immunotherapy
- Principal Investigator
  
  Morisaki Takashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Analysis of the pathway of Smo transcription for development of new therapeutic strategy inhibiting Hedgehog signaling
- Principal Investigator
  
  ONISHI HIDEYA
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Development of Notch4-targeted therapy for patients with HR-negative and HER2-negative breast cancerPrincipal Investigator
- Principal Investigator
  
  KUBO Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
comprehensive breast cancer therapy targeting both estrogen receptor and Hedgehog signaling pathways
- Principal Investigator
  
  TANAKA Haruo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Functional analysis of Gli1 molecule for developing a new inclusive therapy against many tumor species
- Principal Investigator
  
  KATANO Mitsuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Suppression of induction and accumulation at tumor site of regulatory T cells by inhibition of VEGF/VEGFR2 pathway
- Principal Investigator
  
  MORISAKI Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Identification and clinical application of colon cancer-specific gamma-secretase-targeting molecules
- Principal Investigator
  
  YAMAGUCHI Kouji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
治療標的となる乳癌幹細胞の再生・維持機構の解析と治療応用への展開Principal Investigator
- Principal Investigator
  
  久保真
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Development of breast cancer therapy using crosstalk between endocrine signaling pathways and morphogenesis signaling pathways
- Principal Investigator
  
  KOJIMA Masayuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Development of the new strategy by cancer stem cell-targeted therapy for patients with breast cancerPrincipal Investigator
- Principal Investigator
  
  KUBO Makoto
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Development of therapeutic strategy for colorectal cancer by utilizing cross-talk between morphogenesis-related signaling pathways
- Principal Investigator
  
  NOSHIRO Hirokazu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Development of the breast cancer therapy using intercellular transmission by small vesicle (Exosomes) having fusion faculty
- Principal Investigator
  
  KUROKI Shouji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  KYUSHU UNIVERSITY

[Book] 乳癌-基礎・臨床研究のアップデート-2007
- Author(s)
  久保真
- Publisher
  日本臨床
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Book] 乳癌-基礎・臨床研究のアップデート2007
- Author(s)
  久保真
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-18591439
[Journal Article] TP53 and/or BRCA1 Mutations Based on CtDNA Analysis as Prognostic Biomarkers for Primary Triple-Negative Breast Cancer2024
- Author(s)
  Arimura Akiko、Sakai Kazuko、Kaneshiro Kazuhisa、Morisaki Takafumi、Hayashi Saori、Mizoguchi Kimihisa、Yamada Mai、Kai Masaya、Ono Mayumi、Nishio Kazuto、Nakamura Masafumi、Kubo Makoto
- Journal Title
  
  Cancers
  
  Volume: 16 Issue: 6 Pages: 1184-1184
- DOI
  10.3390/cancers16061184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-23K27468
[Journal Article] Immunological analysis of hybrid peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine.2023
- Author(s)
  Morisaki S, Onishi H, Morisaki T, Kubo M, Umebayashi M, Tanaka H, Koya N, Nakagawa S, Tsujimura K, Yoshimura S, Yew PY, Kiyotani K, Nakamura Y, Nakamura M, Kitazono T, Morisaki T.
- Journal Title
  
  Front. Immunol
  
  Volume: 14 Pages: 1223331-1223331
- DOI
  10.3389/fimmu.2023.1223331
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08715, KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-23K24422, KAKENHI-PROJECT-23K27469
[Journal Article] Granzyme B Expression in the Tumor Microenvironment as a Prognostic Biomarker for Patients with Triple-Negative Breast Cancer2023
- Author(s)
  Mizoguchi Kimihisa、Kawaji Hitomi、Kai Masaya、Morisaki Takafumi、Hayashi Saori、Takao Yuka、Yamada Mai、Shimazaki Akiko、Osako Tomofumi、Arima Nobuyuki、Okido Masayuki、Oda Yoshinao、Nakamura Masafumi、Kubo Makoto
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 18 Pages: 4456-4456
- DOI
  10.3390/cancers15184456
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19532
[Journal Article] Significance of the Multi-gene Panel myRisk in Japan2022
- Author(s)
  HAYASHI SAORI、KUBO MAKOTO、MATSUZAKI SAWAKO、KAI MASAYA、MORISAKI TAKAFUMI、YAMADA MAI、KANESHIRO KAZUHISA、TAKAO YUKA、SHIMAZAKI AKIKO、NAGAYOSHI KINUKO、MIZUUCHI YUSUKE、NAKAMURA MASAFUMI
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Issue: 8 Pages: 4097-4102
- DOI
  10.21873/anticanres.15907
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-20K19173
[Journal Article] Genetic medicine is accelerating in Japan2022
- Author(s)
  Hayashi Saori、Kubo Makoto、Kaneshiro Kazuhisa、Kai Masaya、Yamada Mai、Morisaki Takafumi、Takao Yuka、Shimazaki Akiko、Shikada Sawako、Nakamura Masafumi
- Journal Title
  
  Breast Cancer
  
  Volume: 印刷中 Issue: 4 Pages: 659-665
- DOI
  10.1007/s12282-022-01342-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-20K19173
[Journal Article] Lymph nodes as anti-tumor immunotherapeutic tool: intranodal tumor-specific antigen-pulsed dendritic cell vaccine immunotherapy2022
- Author(s)
  Morisaki T, Morisaki T, Kubo M, Morisaki S, Nakamura Y, Onishi H
- Journal Title
  
  Cancers
  
  Volume: 14(10) Issue: 10 Pages: 2438-2438
- DOI
  10.3390/cancers14102438
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08672, KAKENHI-PROJECT-21K08673, KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-23K24422
[Journal Article] CCND1 Copy Number Variation in Circulating Tumor DNA from Luminal B Breast Cancer Patients2022
- Author(s)
  SHIMAZAKI AKIKO、KUBO MAKOTO、KURATA KANAKO、TAKAO YUKA、HAYASHI SAORI、HARADA YURINA、KAWAJI HITOMI、KANESHIRO KAZUHISA、YAMADA MAI、KAI MASAYA、NAKAMURA MASAFUMI
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Issue: 8 Pages: 4071-4077
- DOI
  10.21873/anticanres.15904
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19532
[Journal Article] Validity of the prognostication tool PREDICT version 2.2 in Japanese breast cancer patients2021
- Author(s)
  Karen Zaguirre, Masaya Kai, Makoto Kubo, Mai Yamada, Kanako Kurata, Hitomi Kawaji, Kazuhisa Kaneshiro, Yurina Harada, Saori Hayashi, Akiko Shimazaki, Takafumi Morisaki, Hitomi Mori, Yoshinao Oda, Sanmei Chen, Taiki Moriyama, Shuji Shimizu, Masafumi Nakamura
- Journal Title
  
  Cancer Medicine
  
  Volume: 10 Issue: 5 Pages: 1605-1613
- DOI
  10.1002/cam4.3713
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K19474, KAKENHI-PROJECT-18J20301, KAKENHI-PROJECT-18K08577
[Journal Article] Microsatellite Instability in Japanese Female Patients With Triple-Negative Breast Cancer2020
- Author(s)
  Kurata K, Kubo M, Kai M, Mori H, Kawaji H, Kaneshiro K, Yamada M, Nishimura R, Osako T, Arima N, Okido M, Oda Y, Nakamura M
- Journal Title
  
  Breast Cancer
  
  Volume: 印刷中 Issue: 3 Pages: 490-498
- DOI
  10.1007/s12282-019-01043-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08577, KAKENHI-PROJECT-18J20301
[Journal Article] Comprehensive molecular profiling broadens treatment options for breast cancer patients2020
- Author(s)
  Kawaji Hitomi、Kubo Makoto、Yamashita Nami、Yamamoto Hidetaka、Kai Masaya、Kajihara Atsuko、Yamada Mai、Kurata Kanako、Kaneshiro Kazuhisa、Harada Yurina、Hayashi Saori、Shimazaki Akiko、Mori Hitomi、Akiyoshi Sayuri、Oki Eiji、Oda Yoshinao、Baba Eishi、Mori Masaki、Nakamura Masafumi
- Journal Title
  
  Cancer Medicine
  
  Volume: 10 Issue: 2 Pages: 529-539
- DOI
  10.1002/cam4.3619
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J20301, KAKENHI-PROJECT-18K08577
[Journal Article] FoundationOne CDx gene profiling in Japanese pancreatic ductal adenocarcinoma patients: a single-institution experience2020
- Author(s)
  Kimura R, Ohtsuka T, Kubo M, Kajihara A, Fujii A, Watanabe Y, Mori Y, Ikenaga N, Nakata K, Shindo K, Ohuchida K,Nakamura M
- Journal Title
  
  Surgery Today
  
  Volume: 51 Issue: 4 Pages: 619-626
- DOI
  10.1007/s00595-020-02123-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02881, KAKENHI-PROJECT-18K08577, KAKENHI-PROJECT-20K21633, KAKENHI-PROJECT-20H03753
[Journal Article] T-bet+ lymphocytes infiltration as an independent better prognostic indicator for triple-negative breast cancer2019
- Author(s)
  Mori Hitomi、Kubo Makoto、Kai Masaya、Yamada Mai、Kurata Kanako、Kawaji Hitomi、Kaneshiro Kazuhisa、Osako Tomofumi、Nishimura Reiki、Arima Nobuyuki、Okido Masayuki、Kishimoto Junji、Oda Yoshinao、Nakamura Masafumi
- Journal Title
  
  Breast Cancer Research and Treatment
  
  Volume: 176 Issue: 3 Pages: 569-577
- DOI
  10.1007/s10549-019-05256-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08577, KAKENHI-PROJECT-18J20301
[Journal Article] Usefulness of the nCounter Analysis System to Monitor Immune-related Biomarkers in PBMCs During Anti-PD-1 Therapy2019
- Author(s)
  MORISAKI TAKAFUMI、KUBO MAKOTO、UMEBAYASHI MASAYO、YUAN YUAN、TSUYADA AKIHIRO、TANAKA HIROTO、KOYA NORIHIRO、NAKAGAWA SHINICHIROU、MORISAKI TAKASHI、NAKAMURA MASAFUMI
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Issue: 8 Pages: 4517-4523
- DOI
  10.21873/anticanres.13628
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08577, KAKENHI-PROJECT-19K09047
[Journal Article] Catumaxomab with activated T-cells efficiently lyses chemoresistant EpCAM-positive triple-negative breast cancer cell lines.2018
- Author(s)
  Kubo M, Umebayashi M, Kurata K, Mori H, Kai M, Onishi H, Katano M, Nakamura M, Morisaki T
- Journal Title
  
  Anticancer Research
  
  Volume: 38（７） Issue: 7 Pages: 4273-4279
- DOI
  10.21873/anticanres.12724
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04283, KAKENHI-PROJECT-18J20301
[Journal Article] CD24 suppresses malignant phenotype by downregulation of SHH transcription through STAT1 inhibition in breast cancer cells.2016
- Author(s)
  Suyama K, Onishi H, Imaizumi A, Shinkai K, Umebayashi M, Kubo M, Mizuuchi Y, Oda Y, Tanaka M, Nakamura M, Katano M.
- Journal Title
  
  Cancer Letters
  
  Volume: 374(1) Issue: 1 Pages: 44-53
- DOI
  10.1016/j.canlet.2015.12.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461983, KAKENHI-PROJECT-26293289
[Journal Article] NOTCH4 is a potential therapeutic target for triple-negative breast cancer.2014
- Author(s)
  Nagamatsu I, Onishi H, Matsushita S, Kubo M, Kai M, Imaizumi A, Nakano K, Hattori M, Oda Y, Tanaka M, Katano M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 34(1) Pages: 69-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461983
[Journal Article] NOTCH4 is a potential therapeutic target for triple-negative breast cancer.2014
- Author(s)
  Nagamatsu I, Onishi H, Matsushita S, Kubo M, Kai M, Imaizumi A, Nakano K, Hattori M, Oda Y, Tanaka M, Katano M.
- Journal Title
  
  Ａｎｔｉｃａｎｃｅｒ　Ｒｅｓｅａｒｃｈ
  
  Volume: 34（1） Pages: 69-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591895
[Journal Article] NOTCH4 is a potential therapeutic target for gallbladder cancer2014
- Author(s)
  Nagamatsu I, Onishi H, Matsushita S, Kubo M, Kai M, Imaizumi A, Nakano K, Hattori M, Oda Y, Tanaka M, Katano M
- Journal Title
  
  Anticancer Res
  
  Volume: 34(1) Pages: 69-80
- URL
  http://www.ncbi.nlmnih.gov/pubmed/24403446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591895
[Journal Article] Short-term and low-dose prednisolone administration reduces aromatase inhibitor-induced arthralgia in patients with breast cancer2012
- Author(s)
  Kubo M, Onishi H, Kuroki S, Okido S, Shimada K, Yokohata K, Umeda S, Ogawa T, Tanaka M, Katano M
- Journal Title
  
  Anticancer Res
  
  Volume: 32(6) Pages: 2385-2390
- URL
  http://www.ncbi.nlmnih.gov/pubmed/22641670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591895
[Journal Article] Short-term and low-dose prednisolone administration reduces aromatase inhibitor-induced arthralgia in patients with breast cancer.2012
- Author(s)
  Kubo M, Onishi H, Katano M et al.
- Journal Title
  
  Anticancer Res
  
  Volume: 32(6) Pages: 2331-2336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591895
[Journal Article] Semi-quantitative evaluation of CD44+/CD24- tumor cell distribution in breast cancer tissue using a newly developed fluorescence immunohisto-chemical staining method2011
- Author(s)
  Kai M, Onishi H, Katano M, et al
- Journal Title
  
  Cancer Science
  
  Volume: 102 Issue: 12 Pages: 2132-2138
- DOI
  10.1111/j.1349-7006.2011.02063.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390363, KAKENHI-PROJECT-23591895
[Journal Article] Hedgehog signaling pathway mediates the progression of non-invasive breast cancer to invasive breast cancer2011
- Author(s)
  Souzaki M, Kubo M, Kai M, Kameda C, Tanaka H, Taguchi T, Tanaka M, Onishi H, Katano M.
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 373-381
- NAID
  10029290080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390363
[Journal Article] Oestrogen receptor-αcontributes to the regulation of the hedgehog signaling pathway in ERa-positive gastric cancer2010
- Author(s)
  Kameda C, Nakamura M, Tanaka H, Yamasaki A, Kubo M, Tanaka M, Onishi H, Katano M
- Journal Title
  
  British Journalof Cancer
  
  Volume: 102 Pages: 738-747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390363
[Journal Article] Nuclear factor kappaB-activated monocytes contribute to pancreatic cancer progression through the production of Shh2010
- Author(s)
  Yamasaki A, Kameda C, Xu R, TanakaH, Tasaka T, Chikazawa N, Suzuki H, Morisaki T, Kubo M, Onishi H, Tanaka M, Katano M
- Journal Title
  
  Cancer Immunology Immunotherapy
  
  Volume: 59 Pages: 675-686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390363
[Journal Article] The Hedgehog signaling pathway plays an essential role in maintaining the CD44+ CD24-/low subpopulation and the side population of breast cancer cells2009
- Author(s)
  Tanaka H, Nakamura M, Kameda C, Kubo M, Sato N, Kuroki S, Tanaka M, Katano M
- Journal Title
  
  Anticancer Research
  
  Volume: 29 Pages: 2147-2157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390363
[Journal Article] The hedgehog pathway is a possible therapeutic target for patients with estrogen receptor-negative breast cancer2009
- Author(s)
  Kameda C, Tanaka H, Yamasaki A, Nakamura M, Koga K, Sato N, Kubo M, Tanaka M, Katano M
- Journal Title
  
  Anticancer Res 29
  
  Pages: 871-880
- Data Source
  KAKENHI-PROJECT-19591511
[Journal Article] The hedgehog pathway is a possible therapeutic target for patients with estrogen receptornegative breast cancer2009
- Author(s)
  Kameda C, Tanaka H, Yamasaki A, Nakamura M, Koga K, Sato N, Kubo M, Kuroki S, Tanaka M, Katano M
- Journal Title
  
  Anticancer Research
  
  Volume: 29 Pages: 871-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390363
[Journal Article] Novel Link between Estrogen Receptor a and Hedgehog Pathway in Breast Cancer2008
- Author(s)
  Koga, K, Nakamura, M, Nakashima, H, Akiyoshi, T, Kubo, M, Sato, N, Kuroki, S, Nomura, M, Tanaka, M, Katano, M
- Journal Title
  
  Anticancer Res (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Journal Article] Novel link between estrogen receptor a and hedgehog pathway in breast cancer2008
- Author(s)
  Koga K, Nakamura M, Nakashima H, Akiyoshi T, Kubo M, Sato N, Kuroki S, Nomura M, Tanaka M, Katano M
- Journal Title
  
  Anticancer Res 28
  
  Pages: 731-740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591511
[Journal Article] herapeutic A possible therapeutic application of inhibitors of hedgehog signaling for patients with estrogen receptor-negative breast cancer2008
- Author(s)
  Kameda, C, Nakamura, M, Koga, K, Tanaka, H, Akiyoshi, T, Sato, N, Kubo, M, Tanaka, M, Katano, M
- Journal Title
  
  Anticancer Res (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Journal Article] Anti-patched-1 antibodies suppress hedgehog signaling pathway and pancreatic cancer proliferation2007
- Author(s)
  Nakamura M, Kubo M, Yanai K, Mikami Y, Ikebe M, Nagai S, Yamaguchi K, Tanaka M, Katano M
- Journal Title
  
  Anticancer Res 27
  
  Pages: 3743-3748
- Data Source
  KAKENHI-PROJECT-19591511
[Journal Article] New therapeutic strategy for cancer targeting the hedgehog signaling pathway2007
- Author(s)
  Nakamura, M, Kubo, M, Nagai, S, Yamaguchi, K, Tanaka, M, Katano, M
- Journal Title
  
  Gan To Kagaku Ryoho 34(12)
  
  Pages: 1914-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Journal Article] A New Therapeutic Target of Breast Cancer2007
- Author(s)
  Kubo, M, Kuroki, S, Tanaka, M
- Journal Title
  
  Nihon rinsh 65(6)
  
  Pages: 142-147
- NAID
  40015531653
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Journal Article] Anti-patched-1 antibodies suppress hedgehog signaling pathway and pancreatic cancer proliferation2007
- Author(s)
  Nakamura, M, Kubo, M, Yanai, K, Mikami, Y, Ikebe, M, Nagai, S, Yamaguchi, K, Tanaka, M, Katano, M
- Journal Title
  
  Anticancer Res 27(6A)
  
  Pages: 3743-3748
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Journal Article] Effects ofdocetaxelonantigen presentation- related functions of human monocyte-derived dendritic cells.2005
- Author(s)
  Nakashima H, Tasaki A, Kubo M, Kuroki H, Matsumoto K, Tanaka M, Nakamura M, Morisaki T, Katano M.
- Journal Title
  
  Cancer Immunol Pharmacol 55
  
  Pages: 479-487
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591339
[Journal Article] Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production2005
- Author(s)
  Kubo M et al.
- Journal Title
  
  Cancer Immunol Immunother 54
  
  Pages: 468-476
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591339
[Journal Article] Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production.2005
- Author(s)
  Kubo M, Morisaki T, Tasaki A, Yamanaka N, Nakashima H, Kuroki H, Matsumoto K, Nakamura K, Nakamura M, Katano M.
- Journal Title
  
  Cancer Immunol Immunother 54
  
  Pages: 468-476
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591339
[Journal Article] Purification, characterization and biologic significance of tumor-derived exosomes2005
- Author(s)
  Koga K, Matsumoto K, Akiyoshi T, Kubo M, Yamanaka N, Tasaki A, Nakashima H, Nakamura M, Kuroki S, Tanaka M, Katano M.
- Journal Title
  
  Anticancer Research 25
  
  Pages: 3703-3708
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591339
[Journal Article] The hedgehog signaling pathway plays an essential role in maintaining the CD44+CD24-/low subpopulation and the side population of breast cancer cells
- Author(s)
  Tanaka H, Nakamura M, Kameda C, Kubo M, Sato N, Kuroki S, Tanaka M, Katano M
- Journal Title
  
  Anticancer Res (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591511
[Presentation] 乳癌患者とネオアンチゲン解析との関連性の検討2023
- Author(s)
  溝口公久, 森崎隆史, 甲斐昌也, 高尾由佳, 山田舞, 島﨑亜希子, 林早織, 茂地智子, 伊地知秀樹, 森崎隆, 吉住朋晴, 久保真, 中村雅史
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] 腫瘍遺伝子変異量(TMB):乳癌におけるバイオマーカーとしての意義2023
- Author(s)
  久保真, 森崎隆史, 溝口公久, 中垣環, 馬場英司, 中村雅史
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] 日本人乳癌患者の腸内細菌叢解析についての検討2023
- Author(s)
  山田舞, 久保真, 甲斐昌也, 森崎隆史, 溝口公久, 高尾由佳, 林早織, 島崎亜希子, 古賀艶可, 落合百合菜, 茂地智子, 伊地知秀樹, 吉住朋晴, 中村雅史
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] シングルセルRNA sequencingシークエンシングを用いたHER2陽性乳癌治療抵抗性の網羅的遺伝子解析2022
- Author(s)
  林早織, 久保真, 森瞳美, 甲斐昌也, 山田舞, 金城和寿, 森崎隆史, 高尾由佳, 島﨑亜希子, 中村雅史
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] HBOC診療の現状と課題2022
- Author(s)
  久保真, 鹿田佐和子, 甲斐昌也, 森崎隆史, 木村緑, 小川昌宣, 加藤聖子, 水内祐介, 中村雅史
- Organizer
  第28回日本遺伝性腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] TN乳癌の治療戦略・DNA損傷と腫瘍免疫2022
- Author(s)
  久保真
- Organizer
  第30回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19532
[Presentation] Deep Learning を用いた乳癌 HE 染色画像解析とタンパク発現予測に関する研究2021
- Author(s)
  原田由利菜, 中津川宗秀, 久保真, 甲斐昌也, 山田舞, 森瞳美, 川地眸, 金城和寿, 林早織, 島﨑亜希子, 森崎隆史, 岩崎健, 山元英崇, 小田義直, 中村雅史
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K07637
[Presentation] Deep Learningを用いた乳癌HE染色画像解析2021
- Author(s)
  原田由利菜, 中津川宗秀, 久保真, 甲斐昌也, 山田舞, 森瞳美, 川地眸, 金城和寿, 林早織, 島﨑亜希子, 森崎隆史, 岩崎健, 山元英崇, 小田義直, 中村雅史
- Organizer
  第57回九州外科学会
- Data Source
  KAKENHI-PROJECT-20K07637
[Presentation] 乳癌におけるネオアンチゲン解析の有用性2020
- Author(s)
  久保真, 森崎隆史, 甲斐昌也, 梅林雅代, 島﨑亜希子, 林早織, 原田由利菜, 川地眸, 金城和寿, 倉田加奈子, 森瞳美, 山田舞, 森崎隆, 中村雅史
- Organizer
  第28回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08577
[Presentation] Deep Learningを用いた乳癌HE染色画像解析とタンパク発現予測に関する研究2020
- Author(s)
  原田由利菜, 久保真, 甲斐昌也, 山田舞, 森瞳美, 倉田加奈子, 川地眸, 金城和寿, 林早織, 島﨑亜希子, 森崎隆史, 小田義直, 中津川宗秀, 中村雅史,
- Organizer
  第28回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07637
[Presentation] マルチプレックス遺伝子パネルFoundationOne CDxが変えるHER2陽性乳癌の周術期治療2020
- Author(s)
  久保真, 川地眸, 甲斐昌也, 山田舞, 倉田加奈子, 森瞳美, 金城和寿, 本山由利菜, 林早織, 島﨑亜希子, 森崎隆史, 沖英次, 中村雅史
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08577
[Presentation] Precision Oncology：乳がんゲノムプロファイリングから見えてきたこと2020
- Author(s)
  久保真, 甲斐昌也, 山田舞, 中村雅史
- Organizer
  第26回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08577
[Presentation] Tumor Mutational Burden in Japanese Patients with Triple Negative Breast Cancer2019
- Author(s)
  Kurata K, Kubo M, Yuan Y, Harada Y, Morisaki T, Shimazaki A, Hayashi S, Kawaji H, Kaneshiro K, Yamada M, Kai M, Nakamura M
- Organizer
  The 42nd San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08577
[Presentation] PD-L1 expression of tumor infiltrating immune cells has potential as a biomarker in triple-negative breast cancers2019
- Author(s)
  Harada Y, Kubo M, Mori H, Kai M, Yamada M, Kurata K, Kawaji H, Kaneshiro K, Hayashi S, Shimazaki A, Morisaki T, Yamaguchi R, Arima N, Nishimura R, Okido M, Nakamura M
- Organizer
  The 42nd San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08577
[Presentation] A prospective evaluation of comprehensive tumor profiling busing a targeted Next-generation sequencing for Japanese breast cancer patients2019
- Author(s)
  Kawaji H, Kubo M, Yamashita N, Harada Y, Shimazaki A, Hayashi S, Kurata K, Yamada M, Kaneshiro K, Kai M, Babe E, Oda Y, Nakamura M
- Organizer
  The 42nd San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08577
[Presentation] 乳癌におけるネオアンチゲン解析の意義2019
- Author(s)
  森崎隆史、久保真、梅林雅代、吉村祥子、川地眸、倉田加奈子、金城和寿、森瞳、山田舞、林早織、本山由利菜、甲斐昌也、中村雅史、森崎隆
- Organizer
  第32回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18K08577
[Presentation] Microsatellite Instability in Triple Negative Breast Cancers2018
- Author(s)
  Kanako Kurata, Makoto Kubo, Hitomi Mori, Hitomi Kawaji, Yurina Motoyama, Lumi Kuroki, Mai Yamada, Kazuhisa Kaneshiro, Masaya Kai, Masafumi Nakamura
- Organizer
  The 2018 San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08577
[Presentation] Transcription factor T-bet and PD-L1 expression in tumor microenvironment of triple-negative breast cancer2018
- Author(s)
  Hitomi Mori, Makoto Kubo, Masaya Kai, Kanako Kurata, Hitomi Kawaji, Kazuhisa Kaneshiro, Yurina Motoyama, Rumi Kuroki, Mai Yamada, Reiki Nishimura, Masayuki Okido, Yoshinao Oda, Masafumi Nakamura
- Organizer
  The 2018 San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08577
[Presentation] TNBC-correlation with other markers to predict outcome2016
- Author(s)
  Makoto Kubo
- Organizer
  The 14th Asian Breast Diseases Association Meeting & Symposium
- Place of Presentation
  スカラエスパシオ（福岡県・福岡市）
- Year and Date
  2016-09-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461983
[Presentation] 乳癌におけるCD24分子発現の意義：CD24分子発現とHh経路活性化の連関解析2015
- Author(s)
  巣山久実、大西秀哉、今泉晃、新海健太郎、甲斐昌也、田中晴生、久保真、田中雅夫、片野光男
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25461983
[Presentation] BRCAness and PD-L1 expression of Basal-like and Non-Basal-like Triple Negative Breast Cancer2015
- Author(s)
  Hitomi Mori, Makoto Kubo, Mai Yamada, Masaya Kai, Masayuki Okido, Tomofumi Osako, Reiki Nishimura, Nobuyuki Arima, Yoshinao Oda, Masafumi Nakamura
- Organizer
  The 38th San Antonio Breast Cancer Symposium (2015)
- Place of Presentation
  Henry B. Gonzalez Convention Center・サンアントニオ（米国）
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461983
[Presentation] Hh経路制御による乳癌幹細胞制御療法の開発：CD24分子発現とHh経路活性化の連関解析2014
- Author(s)
  巣山久実、大西秀哉、甲斐昌也、田中晴生、久保真、新海健太郎、永松伊織、松下章次郎、森藤良浩、今泉晃、田中雅夫、片野光男
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-25461983
[Presentation] 乳癌細胞においてHh経路は、CD24-/low分画乳癌細胞の有効な治療標的となる2014
- Author(s)
  巣山　久実、大西　秀哉、今泉　晃、新海　健太郎、久保　真、田中　雅夫、片野　光男
- Organizer
  第27回日本バイオセラピィ学会学術集会総会
- Place of Presentation
  ナレッジキャピタルコングレコンベンションセンター（大阪府・大阪市）
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-26293289
[Presentation] 乳癌細胞におけるCD24分子発現とHh経路活性化の連関の解析2013
- Author(s)
  巣山　久実、大西　秀哉、甲斐　昌也、田中　晴生、久保　真、永松　伊織、今泉　晃、田中　雅夫、片野　光男
- Organizer
  第26回日本バイオセラピィ学会学術集会総会
- Place of Presentation
  いわて県民情報交流センターアイーナ（盛岡市）
- Data Source
  KAKENHI-PROJECT-23591895
[Presentation] トリプルネガティブ乳癌に対する新たな治療標的の同定：Notchシグナル2013
- Author(s)
  永松　伊織、甲斐　昌也、大西　秀哉、久保　真、中野　賢二、田中　雅夫、片野　光男
- Organizer
  第113回日本外科学会定期学術集会
- Place of Presentation
  マリンメッセ福岡（福岡市）
- Data Source
  KAKENHI-PROJECT-23591895
[Presentation] 乳癌細胞におけるCD24分子発現とHh経路活性化の連関の解析2013
- Author(s)
  巣山　久実、大西　秀哉、甲斐　昌也、田中　晴生、久保　真、永松　伊織、今泉　晃、田中　雅夫、片野　光男
- Organizer
  第２６回日本バイオセラピィ学会学術集会
- Place of Presentation
  いわて県民情報交流センターアイーナ（盛岡市）
- Data Source
  KAKENHI-PROJECT-25461983
[Presentation] トリプルネガティブ乳癌に対する新たな治療標的の同定：Notchシグナル系2013
- Author(s)
  永松　伊織、甲斐　昌也、松下　章次郎、大西　秀哉、久保　真、中野　賢二、田中　雅夫、片野　光男
- Organizer
  第２６回日本バイオセラピィ学会学術集会
- Place of Presentation
  いわて県民情報交流センターアイーナ（盛岡市）
- Data Source
  KAKENHI-PROJECT-25461983
[Presentation] トリプルネガティブ乳癌に対する新たな治療標的の同定：Notchシグナル系2013
- Author(s)
  永松　伊織、甲斐　昌也、松下　章次郎、大西　秀哉、久保　真、中野　賢二、田中　雅夫、片野　光男
- Organizer
  第26回日本バイオセラピィ学会学術集会総会
- Place of Presentation
  いわて県民情報交流センターアイーナ（盛岡市）
- Data Source
  KAKENHI-PROJECT-23591895
[Presentation] 乳癌の新しい分子標的治療の可能性:抗Patched1抗体2007
- Author(s)
  久保真
- Organizer
  第15回日本乳癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-06-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] Analysis on relation between ER α and Hedgehog signaling pathway in breast cancer2007
- Author(s)
  Koga, K, Kubo, M, Katano, M, et. al.
- Organizer
  20th Japan Society for Biological Therapy(Workshop)
- Place of Presentation
  Sapporo
- Year and Date
  2007-10-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] Analysis on new therapeutic target for patients with ER positive breast cancer2007
- Author(s)
  Koga, K, Kubo, M, Katano, M, et. al.
- Organizer
  107th Japan Surgical Society
- Place of Presentation
  Osaka
- Year and Date
  2007-04-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] A novel anti-Patched1 antibody can suppress Hedgehog signaling pathway in human breast carcinoma cells2007
- Author(s)
  Kubo M.
- Organizer
  30th San Antonio Breast Cancer Symposium
- Place of Presentation
  San Antonio
- Year and Date
  2007-12-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] Development of identification and maintenance of breast cancer stem cells which are resistant to chemotherapy and radiation2007
- Author(s)
  Tanaka, H, Kubo, M, Katano, M, et. al.
- Organizer
  15th Japanese Breast Cancer Society
- Place of Presentation
  Yokohama
- Year and Date
  2007-07-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] A possible targeted therapy by anti-Patchedl antibody for patients with breast cancer2007
- Author(s)
  Kubo, M, Nakamura, M, Katano, M, et. al.
- Organizer
  107th Japan Surgical Society
- Place of Presentation
  Osaka
- Year and Date
  2007-04-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] Development of the new strategy by cancer stem cell-targeted therapy for patients with breast cancer2007
- Author(s)
  Tanaka, H, Kubo, M, Katano, M, et. al.
- Organizer
  107th Japan Surgical Society
- Place of Presentation
  Osaka
- Year and Date
  2007-04-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] A possible targeted therapy for patients with breast cancer : Anti-Patched1 antibody2007
- Author(s)
  Kubo, M, Nakamura, M, Katano, M, et. al.
- Organizer
  15th Japanese Breast Cancer Society
- Place of Presentation
  Yokohama
- Year and Date
  2007-06-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] Analysis on new therapeutic target for patients with ER positive breast cancer2007
- Author(s)
  Koga, K, Kubo, M, Katano, M, et. al.
- Organizer
  15th Japanese Breast Cancer Society
- Place of Presentation
  Yokohama
- Year and Date
  2007-06-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] Development of the new strategy by cancer stem cell-targeted therapy for patients with breast cancer2007
- Author(s)
  Tanaka, H, Kubo, M, Katano, M, et. al.
- Organizer
  20th Japan Society for Biological Therapy
- Place of Presentation
  Sapporo
- Year and Date
  2007-10-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] 抗Patched1抗体による乳癌の分子標的治療の可能性2007
- Author(s)
  久保真
- Organizer
  第107回日本外科学会定期学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-04-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] A novel anti-Patchedl antibody can suppress Hedgehog signaling pathway in human breast carcinoma cells2007
- Author(s)
  Tanaka, H, Kubo, M, Katano, M, et. al.
- Organizer
  30th San Antonio Breast Cancer Symposium
- Place of Presentation
  San Antonio
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[Presentation] Analysis on new therapeutic target for patients with ER positive breast cancer2006
- Author(s)
  Koga, K, Kubo, M, Katano, M, et. al.
- Organizer
  19th Japan Society for Biological Therapy
- Place of Presentation
  Fukuoka
- Year and Date
  2006-11-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591439
[]

1. ONISHI Hideya (30553276)

# of Collaborated Projects: 11 results

# of Collaborated Products: 21 results
2. KATANO Mitsuo (10145203)

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# of Collaborated Products: 21 results
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46. 池永直樹

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Kubo Makoto 久保 真

KUBO Makoto 久保 真

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Development of therapy-resistant breast cancer treatment using neoantigen-reactive lymphocytesPrincipal Investigator

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Neoantigen analysis in tumor tissues for development of personalized precision cancer immunotherapyPrincipal Investigator

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Development of Notch4-targeted therapy for patients with HR-negative and HER2-negative breast cancerPrincipal Investigator

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Kubo Makoto 久保真

KUBO Makoto 久保真