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Nakano Kazumi  中野 和民

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Kazumi Nakano  中野 和民

NAKANO Kazumi  中野 和民

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Researcher Number 60549591
Other IDs
Affiliation (Current) 2025: 国立健康危機管理研究機構, 国立感染症研究所 次世代生物学的製剤研究センター, 室長
Affiliation (based on the past Project Information) *help 2019 – 2022: 東京大学, 大学院新領域創成科学研究科, 准教授
2017: 東京大学, 大学院新領域創成科学研究科, 准教授
2016: 東京大学, 大学院新領域創成科学研究科, 助教
2011 – 2016: 東京大学, 新領域創成科学研究科, 助教
2009 – 2013: 東京大学, 大学院・新領域創成科学研究科, 助教
Review Section/Research Field
Principal Investigator
Carcinogenesis / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 49060:Virology-related / Tumor biology
Except Principal Investigator
Hematology
Keywords
Principal Investigator
ATL / HTLV-1 / ウイルスタンパク質 / Rex / ウイルス発がん / NMD / 細胞外微小環境 / ATL / HTLV-1 / ウイルスタンパク質機能 … More / 疫学研究 / 疫学調査 / HTLV-1関連疾患 / HTLV-1 a/c / リモート診療 / オーストラリア先住民 / HTLV-1c / 気管支拡張症 / HU / HAM / オーストラリア / HTLV-1c / 日本 / HTLV-1a / 腫瘍化 / 微小環境 / 感染T細胞 / primary PBMC感染実験 / ウイルスタンパク質の相互作用 / HBZ / T細胞 / 感染細胞微小環境 / 潜伏感染細胞 / Hbz / Tax / RNA代謝 / ウイルスRNA / 宿主ウイルス相互作用 / RNA核外輸送 / ウイルス発癌 / 発がんウイルス / 翻訳 / スプライシング / mRNA / 遺伝子発現 / インテラクトーム / RNA輸送 / NMD / Rex / ウイルスゲノムRNA / ウイルス自己複製 / ヒト白血病ウィルス / がん遺伝子 … More
Except Principal Investigator
血液腫瘍学 / ゲノム機能発現 / CD4陽性T細胞 / ドミナントネガティブ / スプライス変異 / Helios / HTLV-1 Tax / CD4 陽性 T 細胞 / NF-κB / シグナル伝達 / エピジェネティクス / NP-κB / HTLV-1 / miRNA / セファランチン / イマチニブ / ハイスループット / トキシコゲノミクス / 薬効評価 / 発現解析 / ATL Less
  • Research Projects

    (9 results)
  • Research Products

    (165 results)
  • Co-Researchers

    (12 People)
  •  Japan-Australia joint study for epidemiological survey of HTLV-1 a/c subtypes and elucidation of their unique pathogenic mechanimsPrincipal Investigator

    • Principal Investigator
      中野 和民
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      The University of Tokyo
  •  Influences of the HTLV-1 viral activities in the determination of the infected cell-fate via hijacking the micro-environment of infected cellsPrincipal Investigator

    • Principal Investigator
      Kazumi Nakano
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      The University of Tokyo
  •  The role of the viral protein Rex in the host-pathogen interaction between HTLV-1 and T cells.Principal Investigator

    • Principal Investigator
      Kazumi Nakano
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      The University of Tokyo
  •  Integrated analysis of abnormal expression profiles that define phenotype of ATL cells

    • Principal Investigator
      Watanabe Toshiki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      St. Marianna University School of Medicine
      The University of Tokyo
  •  Implication of NMD inhibition by Rex to the host cell leukemogenesisPrincipal Investigator

    • Principal Investigator
      NAKANO Kazumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Carcinogenesis
    • Research Institution
      The University of Tokyo
  •  Oncogene addiction of ATL cells and abnormal Polycomb-miRNA-signal transduction

    • Principal Investigator
      WATANABE Toshiki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  HTLV-1 hijacks T-cell differentiation/function by deregulatingHelios gene expression

    • Principal Investigator
      WATANABE Toshiki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  The implication of NMD disruption by HTLV-1 infection in cellular transformationPrincipal Investigator

    • Principal Investigator
      NAKANO Kazumi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Carcinogenesis
    • Research Institution
      The University of Tokyo
  •  Pursuit of a new system for a high throughput screening of drugs to develop a new strategy of prevention and treatment of ATL

    • Principal Investigator
      WATANABE Toshiki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo

All 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Patent

  • [Journal Article] Elucidation of the mechanism of host NMD suppression by HTLV-1 Rex: Dissection of Rex to identify the NMD inhibitory domain2022

    • Author(s)
      Nakano, K., Karasawa N., Hashizume M., Tanaka, Y, Ohsugi, T., Uchimaru. K. and Watanabe, T.
    • Journal Title

      Viruses

      Volume: 14 Issue: 2 Pages: 344-344

    • DOI

      10.3390/v14020344

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-19K07573, KAKENHI-PROJECT-20KK0181
  • [Journal Article] Tuning Rex rules HTLV-1 pathogenesis2022

    • Author(s)
      Kazumi Nakano and Toshiki Watanabe
    • Journal Title

      Frontiers Immunology

      Volume: 13 Pages: 959962-959962

    • DOI

      10.3389/fimmu.2022.959962

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20KK0181
  • [Journal Article] Exploring New Functional Aspects of HTLV-1 RNA-Binding Protein Rex: How Does Rex Control Viral Replication?2022

    • Author(s)
      Kazumi Nakano(corresponding author), Koichi Yokoyama, Shuichi Shin, Koki Uchida, Kazuki Tsuji, Marie Tanaka, Kaoru Uchimaru, and Toshiki Watanabe
    • Journal Title

      Viruses

      Volume: 14 Issue: 2 Pages: 407-407

    • DOI

      10.3390/v14020407

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07573, KAKENHI-PROJECT-20KK0181
  • [Journal Article] Overexpression of aberrant Wnt5a and its effect on acquisition of malignant phenotypes in adult T-cell leukemia/lymphoma (ATL) cells.2021

    • Author(s)
      Nakano K., Chihara Y., Kobayashi S., Iwanaga M., Utsunomiya A., Watanabe T., and Uchimaru K.
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 4114-4114

    • DOI

      10.1038/s41598-021-83613-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07573, KAKENHI-PROJECT-20KK0181, KAKENHI-PROJECT-16H06277
  • [Journal Article] Dysregulation of c-Myb Pathway by Aberrant Expression of Proto-oncogene MYB Provides the Basis for Malignancy in Adult T-cell Leukemia/lymphoma Cells.2016

    • Author(s)
      Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T.
    • Journal Title

      Clin Cancer Res

      Volume: 22 Issue: 23 Pages: 5915-5928

    • DOI

      10.1158/1078-0432.ccr-15-1739

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05248, KAKENHI-PROJECT-15K06827, KAKENHI-PROJECT-16H06277
  • [Journal Article] Dysregulation of c-Myb Pathway by Aberrant Expression of Proto-oncogene MYB Provides the Basis for Malignancy in Adult T-cell Leukemia/lymphoma Cells2016

    • Author(s)
      Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T
    • Journal Title

      Clin Cancer Res

      Volume: 22(23) Pages: 5915-5928

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Journal Article] Polycomb-dependent epigenetic landscape in adult T-cell leukemia.2016

    • Author(s)
      Dai Fujikawa; Shota Nakagawa; Makoto Hori; Naoya Kurokawa; Ai Soejima; Kazumi Nakano; Tadanori Yamochi; Makoto Nakashima; Seiichiro Kobayashi; Yuetsu Tanaka; Masako Iwanaga; Atae Utsunomiya; Kaoru Uchimaru; Makoto Yamagishi; Toshiki Watanabe
    • Journal Title

      Blood

      Volume: 127 Issue: 14 Pages: 1790-1802

    • DOI

      10.1182/blood-2015-08-662593

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J08236, KAKENHI-PROJECT-16H05248, KAKENHI-PROJECT-16H05323, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-15K06907, KAKENHI-PROJECT-16H06277
  • [Journal Article] HTLV-1 Rex Tunes the Cellular Environment Favorable for Viral Replication2016

    • Author(s)
      Kazumi Nakano and Toshiki Watanabe
    • Journal Title

      Viruses

      Volume: 8 Issue: 3 Pages: 1-18

    • DOI

      10.3390/v8030058

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06827
  • [Journal Article] Advanced HTLV-1 carriers and early-stage indolent ATLs are indistinguishable based on CADM1 positivity in flow cytometry2015

    • Author(s)
      Kobayashi S, Watanabe E, Ishigaki T, Ohno N, Yuji K, Nakano K, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K.
    • Journal Title

      Cancer Sci

      Volume: 印刷中 Issue: 5 Pages: 598-603

    • DOI

      10.1111/cas.12639

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24501304, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-14J07244
  • [Journal Article] CADM1 expression and stepwise downregulation of CD7 are closely associated with clonal expansion of HTLV-1-infected cells in adult T-cell leukemia/lymphoma2014

    • Author(s)
      Kobayashi S, Nakano K, Watanabe E, Ishigaki T, Ohno N, Yuji K, Oyaizu N, Asanuma S, Yamagishi M, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K
    • Journal Title

      Clin Cancer Res

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Journal Article] Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia2014

    • Author(s)
      Takahashi R; Yamagishi M, Nakano K, Yamochi T, Yamochi T, Fujikawa D, Nakashima M, Tanaka Y, Uchimaru K, Utsunomiya A, Watanabe T
    • Journal Title

      Cancer Sci

      Volume: 105 Issue: 9 Pages: 1160-1169

    • DOI

      10.1111/cas.12480

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24501304, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-221S0001
  • [Journal Article] CADM1 expression and stepwise downregulation of CD7 are closely associated with clonal expansion of HTLV-I-infected cells in adult T-cell leukemia/lymphoma2014

    • Author(s)
      Kobayashi S, Nakano K, Watanabe E, Ishigaki T, Ohno N, Yuji K, Oyaizu N, Asanuma S, Yamagishi M, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K
    • Journal Title

      Clinical Cancer Research

      Volume: 20(11) Issue: 11 Pages: 2851-61

    • DOI

      10.1158/1078-0432.ccr-13-3169

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J07244, KAKENHI-PROJECT-24501304, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-221S0001
  • [Journal Article] Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T-cell growth.2013

    • Author(s)
      Asanuma S, Uchimaru K, et al.
    • Journal Title

      Cancer Sci

      Volume: - Issue: 8 Pages: 1097-1106

    • DOI

      10.1111/cas.12181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591028, KAKENHI-PROJECT-23390250, KAKENHI-PROJECT-23659484, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-24790436, KAKENHI-PROJECT-221S0001
  • [Journal Article] Viral interference with host mRNA surveillance, the nonsense-mediated mRNA decay (NMD) pathway, through a new function of HTLV-1 Rex: implications for retroviral replication.2013

    • Author(s)
      Nakano, K., Ando, T., Yamagishi, M., Yokoyama, K., Ishida, T., Ohsugi, T., Tanaka, Y., Brighty, D. W. and Watanabe, T.
    • Journal Title

      Microbes and Infection

      Volume: 15 Issue: 6-7 Pages: 491-505

    • DOI

      10.1016/j.micinf.2013.03.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500493, KAKENHI-PROJECT-24501304, KAKENHI-PROJECT-221S0001
  • [Journal Article] Polycomb-Mediated Loss of miR-31 Activates NIK-dependent NF-κB Pathway in Adult T-cell Leukemia and Other Cancers2012

    • Author(s)
      Yamagishi M, Uchimaru K, et al.
    • Journal Title

      Cancer cell

      Volume: 21 Issue: 1 Pages: 121-135

    • DOI

      10.1016/j.ccr.2011.12.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591028, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-23390250, KAKENHI-PROJECT-24790436, KAKENHI-PLANNED-22134006
  • [Journal Article] 特集:抗ウイルス薬 III.新規抗ウイルス薬の開発動向と展望「抗HTLV-1薬開発の現状」2012

    • Author(s)
      中野和民、渡邉俊樹
    • Journal Title

      日本臨床

      Volume: 70(4) Pages: 671-675

    • Data Source
      KAKENHI-PROJECT-23390250
  • [Journal Article] HTLV-1 Rex: the courier of viral messages, making use of the host vehicle2012

    • Author(s)
      Nakano K, Watanabe T
    • Journal Title

      Front Microbiol

      Volume: 3:330 Pages: 330-330

    • DOI

      10.3389/fmicb.2012.00330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390250, KAKENHI-PROJECT-24501304, KAKENHI-PROJECT-221S0001
  • [Journal Article] SMYD3 interacts with HTLV-1 Tax and regulates sub-cellular localization of Tax2011

    • Author(s)
      Yamamoto K, Ishida T, Nakano K, Yamagishi M, Yamochi T, Tanaka Y, Furukawa Y, Nakamura Y, Watanabe T
    • Journal Title

      Cancer Science

      Volume: 102 Pages: 260-266

    • NAID

      10029289377

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Journal Article] SMYD3 interacts with HTLV-1 Tax and regulates sub-cellular localization of Tax.2011

    • Author(s)
      Yamamoto K, Ishida T, Nakano K, Yamagishi M, Yamochi T, Tanaka Y, Furukawa Y, Nakamura Y, Watanabe T.
    • Journal Title

      Cancer Sci 102(1)

      Pages: 260-266

    • NAID

      10029289377

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Patent] 抗CADM1抗体2021

    • Inventor(s)
      中野和民、高橋良明、田部亜季、渡邉俊樹、津本浩平
    • Industrial Property Rights Holder
      中野和民、高橋良明、田部亜季、渡邉俊樹、津本浩平
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-080133
    • Filing Date
      2021
    • Acquisition Date
      2021
    • Data Source
      KAKENHI-PROJECT-19K07573
  • [Patent] 抗CADM1抗体2021

    • Inventor(s)
      中野和民、高橋良明、田部亜季、渡邉俊樹、津本浩平
    • Industrial Property Rights Holder
      中野和民、高橋良明、田部亜季、渡邉俊樹、津本浩平
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-080133
    • Filing Date
      2021
    • Acquisition Date
      2021
    • Data Source
      KAKENHI-PROJECT-20KK0181
  • [Presentation] 新規抗CADM1抗体を用いた成人T細胞白血病・リンパ腫細胞に対する抗体薬物複合体の開発2022

    • Author(s)
      田部 亜季、高橋 良明、那須 智博、由井 杏奈、中木 戸誠、内丸 薫、渡邉 俊樹、津本 浩平、中野 和民
    • Organizer
      第8回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-20KK0181
  • [Presentation] 新規CADM1抗体-FoxM1阻害剤複合体によるATL細胞への標的治療の試み2022

    • Author(s)
      中野 和民、田部 亜季、高橋 良明、山本 菜央佳、津本 浩平、渡邉 俊樹、内丸 薫
    • Organizer
      第8回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-20KK0181
  • [Presentation] HTLV-1機能タンパク質群のインテラクティブな働きとHTLV-1感染の成立2021

    • Author(s)
      中野 和民、田中 稀瑛、内田 弘毅、渡邉 俊樹、内丸 薫
    • Organizer
      第7回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07573
  • [Presentation] HTLV-1感染の場におけるウイルスタンパク質の相互制御機構と相乗的機能の解析2021

    • Author(s)
      中野 和民、田中 稀瑛、内田 弘毅、渡邉 俊樹、内丸 薫
    • Organizer
      第68回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07573
  • [Presentation] HTLV-1感染の場におけるウイルスタンパク質の相互制御機構と相乗的機能の解析2021

    • Author(s)
      中野 和民、田中 稀瑛、内田 弘毅、渡邉 俊樹、内丸 薫
    • Organizer
      第68回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-20KK0181
  • [Presentation] HTLV-1機能タンパク質群のインテラクティブな働きとHTLV-1感染の成立2021

    • Author(s)
      中野 和民、田中 稀瑛、内田 弘毅、渡邉 俊樹、内丸 薫
    • Organizer
      第7回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-20KK0181
  • [Presentation] Exploring the biological impact of HTLV-1 Rex on dysregulation of the host T-cell splicing machinery2020

    • Author(s)
      Marie Tanaka, Koki Uchida, Toshiki Watanabe, Kaoru Uchimaru, and Kazumi Nakano
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07573
  • [Presentation] Examination of effects and the mode-of-action of a new drug candidate, Darinaparsin, on adult T-cell leukemia/lymphoma (ATL) cells2020

    • Author(s)
      Tomohiro Nasu, Aki Tanabe, Toshiki Watanabe, Kaoru Uchimaru, and Kazumi Nakano
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07573
  • [Presentation] HTLV-1 Rexの宿主スプライシング機構制御における新規機能の探索2019

    • Author(s)
      内田 弘毅、渡邉 俊樹、内丸 薫、中野 和民
    • Organizer
      第6回 日本HTLV-1学会
    • Data Source
      KAKENHI-PROJECT-19K07573
  • [Presentation] HTLV-1感染および腫瘍化と関連するエクソソーム表面抗原マーカー同定の試み2019

    • Author(s)
      中野 和民、宇都宮 與、渡邉 俊樹、内丸 薫
    • Organizer
      第6回 日本HTLV-1学会
    • Data Source
      KAKENHI-PROJECT-19K07573
  • [Presentation] Exploring new functional aspects of HTLV-1 Rex to manipulate host-cellular pathways for viral replication2017

    • Author(s)
      Kazumi Nakano, Koichi Yokoyama, Shuichi Sin, Nobuaki Karasawa, Toshiki Watanabe, Kaoru Uchimaru
    • Organizer
      18thInternational Conference on Human Retrovirology HTLV-1 and Related Viruses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06827
  • [Presentation] Development and Molecular Analysis of Synthetic Lethality by Targeting EZH1/2 in ATL and HTLV-1-infected cells2017

    • Author(s)
      Yamagishi M, Hori M, Fujikawa D, Honma D, Adachi N, Ohsugi T, Nakano K, Nakashima M, Kobayashi S, Iwanaga M, Utsunomiya A, Tanaka Y, Okada S, Tsukasaki K, Tobinai K, Araki K, Watanabe T, Uchimaru K
    • Organizer
      18th International Conference on Human Retrovirology:HTLV and Related Viruses
    • Place of Presentation
      Hotel Grand Ark Hanzomon, Tokyo
    • Year and Date
      2017-03-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] The functions of a transcription factor STAT3 in Tax-expressing HTLV-1-infected cells2017

    • Author(s)
      Shiga H, Yamagishi M, Fujikawa D, Nakano K, Utsunomiya A, Tanaka Y, Watanabe T, Uchimaru K
    • Organizer
      18th International Conference on Human Retrovirology:HTLV and Related Viruses
    • Place of Presentation
      Hotel Grand Ark Hanzomon, Tokyo
    • Year and Date
      2017-03-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Comparative Transcriptome Analysis of HTLV-1-infected cells and ATL cells2017

    • Author(s)
      Yamagishi M, Nakano K, Fujikawa D, Kobayashi S, Araya N, Sato T, Yagishita N, Iwanaga M, Utsunomiya A, Tanaka Y, Yamano Y, Watanabe T, Uchimaru K
    • Organizer
      18th International Conference on Human Retrovirology:HTLV and Related Viruses
    • Place of Presentation
      Hotel Grand Ark Hanzomon, Tokyo
    • Year and Date
      2017-03-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Development and molecular analysis of synthetic lethality by targeting EZH1 and EZH2 in T cell lymphomas2017

    • Author(s)
      Yamagishi M, Hori M, Fujikawa D, Honma D, Adachi N, Ohsugi T, Nakano K, Nakashima M, Kobayashi S, Iwanaga M, Utsunomiya A, Okada S, Tsukasaki K, Tobinai K, Araki K, Watanabe T, Uchimaru K
    • Organizer
      9th Annual T-Celll Lymphoma Forum
    • Place of Presentation
      San Francisco, CA, U.S.A.
    • Year and Date
      2017-01-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Exploring new functional aspects of HTLV-1 Rex to manipulate host-cellular pathways for viral replication2017

    • Author(s)
      Kazumi Nakano, Koichi Yokoyama, Shuichi Sin, Nobuaki Karasawa, Toshiki Watanabe, Kaoru Uchimaru
    • Organizer
      18th Internatial Conference on Human Retrovirology: HTLV-1 and Related Viruses
    • Place of Presentation
      Hotel Grand Arc Hanzomon, Tokyo, Japan
    • Year and Date
      2017-03-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06827
  • [Presentation] Exploring new functional aspects of HTLV-1 Rex to manipulate host-cellular pathways for viral replication2017

    • Author(s)
      Nakano K, Yokoyama K, Sin S, Karasawa N, Watanabe T, Uchimaru K
    • Organizer
      18th International Conference on Human Retrovirology:HTLV and Related Viruses
    • Place of Presentation
      Hotel Grand Ark Hanzomon, Tokyo
    • Year and Date
      2017-03-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] ウイルス複製に有利な細胞内環境整備を可能にするHTLV-1 Rexの新たな機能的側面の探索2017

    • Author(s)
      中野 和民、横山 弘一、慎 秀一、唐澤 伸明、渡邉 俊樹、内丸 薫
    • Organizer
      第4回 日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K06827
  • [Presentation] Synergistic-loop between FoxM1 and c-Myb is responsible for proliferative/invasive phenotypes of ATL cells2016

    • Author(s)
      Kazumi Nakano, Aki Nishida, Makoto Nakakido, Yohei Chihara, Seiichiro Kobayashi, Yuetsu Tanaka, Atae Utsunomiya, Kohei Tsumoto, Kaoru Uchimaru, and Toshiki Watanabe
    • Organizer
      第5回日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K06827
  • [Presentation] Proto-oncogene MYB発現異常によるc-Myb経路撹乱がATL細胞悪性化形質を規定する2016

    • Author(s)
      中野和民、宇都宮與、山口一成、内丸 薫、渡邉俊樹
    • Organizer
      第3回日本HTLV-1学会学術集会
    • Place of Presentation
      鹿児島県市町村自治会館、鹿児島
    • Year and Date
      2016-08-28
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] ATL細胞におけるシグナル伝達系の異常な活性化の機構と意義2016

    • Author(s)
      渡邉俊樹、山岸 誠、中野和民、内丸薫
    • Organizer
      第75回日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-10-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Proto-oncogene MYB発現異常によるc-Myb経路撹乱がATL細胞悪性化形質を規定する2016

    • Author(s)
      中野 和民、宇都宮 與、山口 一成、内丸 薫、渡邉 俊樹
    • Organizer
      第3回日本HTLV-1学会学術集会
    • Place of Presentation
      鹿児島県市町村自治会館(鹿児島県)
    • Year and Date
      2016-08-26
    • Data Source
      KAKENHI-PROJECT-15K06827
  • [Presentation] エピジェネティクスを基盤とした成人T細胞白血病の新たな治療戦略2016

    • Author(s)
      山岸誠、藤川大、大杉剛生、堀真琴、中野和民、小林誠一郎、岩永正子、宇都宮與、内丸薫、渡邉俊樹
    • Organizer
      第75回日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Development and Molecular Analysis of Synthetic Lethality By Targeting EZH1 and EZH2 in Non-Hodgkin Lymphomas2016

    • Author(s)
      Yamagishi M, Hori M, Fujikawa D, Honma D, Adachi N, Ohsugi T, Nakano K, Nakashima M, Kobayashi S, Iwanaga M, Utsunomiya A, Okada S, Tsukasaki K, Tobinai K, Araki K, Watanabe T, Uchimaru K
    • Organizer
      the 58th ASH Annual Meeting and Exposition
    • Place of Presentation
      San Diego, CA, U.S.A.
    • Year and Date
      2016-12-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Quantitative and qualitative disorders of the Wnt5a pathway in ATL cells2016

    • Author(s)
      Kazumi Nakano, Yohei Chihara, Seiichiro Kobayashi, Kaoru Uchimaru, and Toshiki Watanabe
    • Organizer
      第78回血液学会学術集会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K06827
  • [Presentation] FoxM1とc-Myb間の相乗的活性化ループがATL細胞の悪性化形質を規定する2016

    • Author(s)
      中野和民、田部亜季、中木戸誠、千原庸平、小林誠一郎、田中勇悦、宇都宮與、津本浩一、内丸薫、渡邉俊樹
    • Organizer
      第75回日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Epigenetic landscape in adult T cell leukemia-lymphoma (ATL); proof of concept for targeting EZH1/22016

    • Author(s)
      山岸誠、藤川大、大杉剛生、本間大輔、安達宣明、堀真琴、中川翔太、中野和民、小林誠一郎、田中勇悦、岩永正子、宇都宮與、塚崎邦弘、荒木一司、内丸薫、渡邉俊樹
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] 成人T細胞白血病(ATL)の遺伝子翻訳異常とその意義2016

    • Author(s)
      山岸誠、澤礼乃、藤川大、堀真琴、中野和民、宇都宮與、渡邉俊樹、内丸薫
    • Organizer
      第3回日本HTLV-1学会学術集会
    • Place of Presentation
      鹿児島県市町村自治会館、鹿児島
    • Year and Date
      2016-08-27
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Polycomb-dependent epigenetic landscape in adult T cell leukemia (ATL); providing proof of concept for targeting EZH1/2 to selectively eliminate the HTLV-1 infected population2016

    • Author(s)
      Yamagishi M, Fujikawa D, Ohsugi T, Honma D, Adachi N, Nakagawa S, Hori M, Kurokawa N, Soejima A, Nakano K, Yamochi T, Nakashima M, Kobayashi S, Tanaka Y, Iwanaga M, Utsunomiya A, Uchimaru K, Tsukasaki K, Araki K, Watanabe T
    • Organizer
      T-cell Lymphoma Forum 2016
    • Place of Presentation
      San Francisco, CA, U.S.A.
    • Year and Date
      2016-01-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Quantitative and qualitative disorders of the Wnt5a pathway in ATL cells2016

    • Author(s)
      中野和民、千原庸平、小林誠一郎、内丸薫、渡邉俊樹
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Polycomb-Dependent Epigenetic Landscape in Adult T Cell Leukemia (ATL); Providing Proof of Concept for Targeting EZH1/2 to Selectively Eliminate the HTLV-1 Infected Population2015

    • Author(s)
      Yamagishi M, Fujikawa D, Honma D, Adachi N, Nakagawa S, Hori M, Kurokawa N, Soejima A, Nakano K, Yamochi T, Nakashima M, Kobayashi S, Tanaka Y, Iwanaga M, Utsunomiya A, Uchimaru K, Tsukasaki K, Araki K, Watanabe T
    • Organizer
      the 57th ASH Annual Meeting and Exposition
    • Place of Presentation
      Orlando, FL, U.S.A.
    • Year and Date
      2015-12-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] ATL細胞特異的なエピゲノム異常を制御するEZH2の質的、量的変化2015

    • Author(s)
      堀真琴、山岸誠、藤川大、中川翔太、中野和民、田中勇悦、小林誠一郎、宇都宮與、内丸薫、渡邉俊樹
    • Organizer
      第2回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所(東京都港区)
    • Year and Date
      2015-08-22
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] EZH2-dependent epigenetic landscape in adult T-cell leukemia and Tax-immortalized cells2015

    • Author(s)
      Fujikawa D, Yamagishi M, Nakagawa S, Kurokawa N, Soejima A, Kobayashi S, Uchimaru K, Tanaka Y, Nakano K, Watanabe T
    • Organizer
      17th Internatioal Conference on Human Retrovilrology HTLV & Related Viruses
    • Place of Presentation
      the Carayou Hotel, Martinique, France
    • Year and Date
      2015-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] 成人T細胞白血病におけるTAK1-p38経路の活性化とその意義2015

    • Author(s)
      澤礼乃、山岸誠、酒井直規、藤川大、中野和民、宇都宮與、内丸薫、渡邉俊樹
    • Organizer
      第2回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所(東京都港区)
    • Year and Date
      2015-08-22
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] ATL細胞におけるEZH2依存的なエピゲノム異常とその原因メカニズムの解析2015

    • Author(s)
      藤川大、山岸誠、堀真琴、中野和民、田中勇悦、小林誠一郎、宇都宮與、内丸薫、渡邉俊樹
    • Organizer
      第2回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所(東京都港区)
    • Year and Date
      2015-08-22
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Tumor-specific gene expression leads to p38 and Hedgehog signaling activation in adult T cell leukemia2014

    • Author(s)
      Yamagishi M, Takahashi R, Sakai N, Fujikawa D, Nakagawa S, Yamochi T, Yamochi T, Nakano K, Uchimaru K, Utsunomiya A, Watanabe T
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場、大阪
    • Year and Date
      2014-11-01
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] Human T-Lymphotropic Virus Type 1 Biomarkers in Patients with Rheumatoid Arthritis2014

    • Author(s)
      Okayama A, Iwanaga M, Sagara Y, Hidaka T, Umekita K, Nakano K, Watanabe T, Yamano Y, Horai Y, Nakamura H, Kawakami A
    • Organizer
      ACR/ARHP Annual Meeting
    • Place of Presentation
      Boston, U.S.A
    • Year and Date
      2014-11-18
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] 成人T細胞白血病におけるEZH2依存的エピジェネティック異常の包括的解析2014

    • Author(s)
      堀真琴、藤川大、中川翔太、田中勇悦、中野和民、渡邉俊樹、山岸誠
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2014-11-25
    • Data Source
      KAKENHI-PROJECT-26293226
  • [Presentation] HAS-Flow法を用いたHTLV-1キャリア/くすぶり型ATL境界の検討2013

    • Author(s)
      小林誠一郎、渡辺恵理、石垣知寛、中野和民、矢持忠徳、山岸誠、浅沼里実、大野伸広、湯地晃一郎、渡辺信和、東條有伸、渡邉俊樹、内丸薫
    • Organizer
      第6回HTLV-1研究会・シンポジウム
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Molecular hallmarks of adult T cell leukemia : miRNA, pigenetics, and emerging signaling abnormalities2013

    • Author(s)
      Yamagishi M, Fujikawa D, Kurokawa N, Soejima A, Takahashi R, Sakai N, Nakagawa S, Nakano K, Kobayashi S, Utsunomiya A, Yamaguchi K, Uchimaru K, Ogawa S, Watanabe T
    • Organizer
      16th International Conference on Human Retrovirology HTLV and Related Viruses
    • Place of Presentation
      Montreal, Canada
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] 成人T細胞白血病におけるポリコームファミリーの過剰発現機構の解析2013

    • Author(s)
      中川翔太、山岸誠、藤川大、中野和民、宇都宮與、内丸薫、渡邉俊樹
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Disorders of the cMyb proto-oncogene expression and its significance in the course of ATL development2013

    • Author(s)
      Nakano K, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      16th International Conference on Human Retrovirology HTLV and Related Viruses
    • Place of Presentation
      Montreal, Canada
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Diverse ways of modulating Polycomb group function and host epigenome in adult T cell leukemia2013

    • Author(s)
      Yamagishi M, Fujikawa D, Kurokawa N, Soejima A, Nakagawa S, Nakano K, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] HTLV-1 Tax disrupts the host epigenome by interacting with a Polycomb group protein EZH22013

    • Author(s)
      Fujikawa D, Yamagishi M, Kurokawa N, Soejima A, Ishida T, Tanaka Y, Nakano K, Watanabe T
    • Organizer
      平成25年度東京大学医科学研究所研究成果発表会
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Molecular hallmarks of adult T cell leukemia: miRNA, pigenetics, and emerging signaling abnormalities2013

    • Author(s)
      Yamagishi M, Fujikawa D, Kurokawa N, Soejima A, Takahashi R, Sakai N, Nakagawa S, Nakano K, Kobayashi S, Utsunomiya A, Yamaguchi K, Uchimaru K, Ogawa S, Watanabe T
    • Organizer
      16th International Conference on Human Retrovirology HTLV and Related Viruses
    • Place of Presentation
      Montreal, Canada
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] 成人T細胞白血病におけるp38シグナル伝達系の異常とその意義2013

    • Author(s)
      酒井直規、山岸誠、藤川大、中野和民、宇都宮與、内丸薫、渡邉俊樹
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] ATL細胞におけるp38シグナル伝達系の異常とNF-κB経路への影響2013

    • Author(s)
      酒井直規、山岸誠、藤川大、中野和民、宇都宮與、内丸薫、渡邉俊樹
    • Organizer
      第6回HTLV-1研究会・シンポジウム
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] The CD7 vs CADM1 plot in FACS is useful for selecion of advanced HTLV-1 carriers2013

    • Author(s)
      Kobayashi S, Watanabe E, Ishigaki T, Ohno N, Yuji K, Nakano K, Yamochi T, Watanabe T, Watanabe N, Tojo A, Uchimaru K
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      ロイトン札幌, 札幌
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] HTLV-1 Tax disrupts the host epigenome by interacting with a Polycomb group protein EZH22013

    • Author(s)
      Fujikawa D, Yamagishi M, Kurokawa N, Soejima A, Ishida T, Tanaka Y, Nakano K, Watanabe T
    • Organizer
      16th International Conference on Human Retrovirology HTLV and Related Viruses
    • Place of Presentation
      Montreal, Canada
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] 宿主mRNA品質管理機構(NMD)抑制を司るHTLV-1 Rexの機能ドメインの解析2013

    • Author(s)
      唐澤 伸明、中野 和民、安東 知美、橋爪 大明、横山 弘一、渡邉 俊樹
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] Cordinated epigenetic reglulation of mRNAs activates simultaneous signaling in maglignart lymphoma2013

    • Author(s)
      Yamagishi M, Katano H, Nakano K, Ota Y, Hishima T, Okada S, Watanabe T
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] 成人T細胞白血病細胞におけるポリコームタンパク質の過剰発現機構の解析2013

    • Author(s)
      中川翔太、山岸誠、藤川大、中野和民、宇都宮與、内丸薫、渡邉俊樹
    • Organizer
      第6回HTLV-1研究会・シンポジウム
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] ATLにおけるEZH2過剰発現の分子メカニズム2013

    • Author(s)
      中川翔太、山岸誠、藤川大、中野和民、宇都宮與、内丸薫、渡邉俊樹
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] 腫瘍別シンポジウム「リンパ腫におけるエピジェネティック依存的なmiRNAの発現異常とシグナル伝達系の活性化」2013

    • Author(s)
      山岸誠、片野晴隆、中川翔太、中野和民、太田泰徳、比島恒和、岡田誠治、渡邉俊樹
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Diverse ways of modulating Polycomb group function and host epigenome in adult T cell leukemia2013

    • Author(s)
      Yamagishi M, Fujikawa D, Kurokawa N, Soejima A, Nakagawa S, Nakano K, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      ロイトン札幌, 札幌
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] ウイルス複製を有利にするHTLV-1 Rex の新たな機能の可能性と 宿主細胞への影響2013

    • Author(s)
      中野 和民
    • Organizer
      第6回HTLV-1研究会
    • Place of Presentation
      東京大学医科学研究所
    • Invited
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] The CD7 vs CADM1 plot in FACS is useful for selecion of advanced HTLV-1 carriers2013

    • Author(s)
      Kobayashi S, Watanabe E, Ishigaki T, Ohno N, Yuji K, Nakano K, Yamochi T, Watanabe T, Watanabe N, Tojo A, Uchimaru K
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] mRNA品質管理機構(NMD)阻害に関わるHTLV-1 Rexの 機能ドメインの特定及び相互作用するNMD因子の同定2013

    • Author(s)
      唐澤 伸明、中野 和民、安東 知美、橋爪 大明、横山 弘一、渡邉 俊樹
    • Organizer
      第6回HTLV-1研究会
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] スプライシングとmRNA品質管理機構の二重不全によるATL細胞でのPTC含有異常転写産物の高発現とその影響2013

    • Author(s)
      中野和民、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] HTLV-1タンパク質TaxとPolycombタンパク質EZH2との相互作用を介して宿主細胞のエピゲノムを撹乱し、腫瘍化の進行に寄与する2013

    • Author(s)
      藤川大、山岸誠、中川翔太、黒川直也、副島あい、中野和民、宇都宮與、内丸薫、石田尚臣、田中勇悦、渡邉俊樹
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] HTLV-1タンパク質Taxはポリコームタンパク質EZH2との相互作用を介してエピゲノムを撹乱する2013

    • Author(s)
      藤川大、山岸誠、黒川直也、副島あい、石田尚臣、田中勇悦、中野和民、渡邉俊樹
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Aberrrantly spliced Helios variants in ATL cells induce T cellproliferation2012

    • Author(s)
      Asanuma S, Nakano K, Yamagishi M, Ogawa S, Yamaguchi K, Utsunomiya A, Watanabe T
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都国際会議場
    • Data Source
      KAKENHI-PROJECT-23659484
  • [Presentation] 成人T細胞白血病から明らかになった新たなクロストーク:Polycomb-miR-31-NF-kB経路の異常とがん2012

    • Author(s)
      山岸誠、中野和民、宇都宮與、山口一成、内丸薫、小川誠司、渡邉俊樹
    • Organizer
      平成24年度東京大学医科学研究所研究成果発表会
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] HTLV-1タンパク質TaxはPolycombタンパク質EZH2との相互作用を介してエピジェネティクスの脱制御を誘導する2012

    • Author(s)
      藤川大, 山岸誠, 黒川直也, 副島あい, 石田尚臣, 中野和民, 渡邉俊樹
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] HTLV-1 RexにおるmRNA品質管理機構(NMD)の抑制及び宿主T細胞への影響2012

    • Author(s)
      横山弘一、中野和民、安東友美、大杉剛生、田中勇悦、渡邉俊樹
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] Molecular hallmarks of adult T cell leukemia : miRNA epigenetics and emerging signaling abnormalities2012

    • Author(s)
      Yamagishi M, Takahashi R, Nakano K, Asanuma S, Utsunomiya A, Yamaguchi K, Uchimaru K, Ogawa S, Watanabe T
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都国際会議場
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] HTLV-1 viral protein Tax mediates epigenetic deregulation by interaction with a Polycomb group protein, EZH22011

    • Author(s)
      藤川大, 山岸誠, 黒川直也, 副鳥あい, 石田尚臣, 中野和民, 渡邉俊樹
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] A Novel Function of HTLV-1 Rex in Inhibition of the Host mRNA Surveillance Mechanism (NMD) for Protection of the Viral Genomic mRNA2011

    • Author(s)
      Nakano K, Ando T, Ishida T, Ohsugi T, Tanaka Y, Watanabe T
    • Organizer
      The 15^<th> International Conference on Human Retrovirology : HTLV and Related Viruses
    • Place of Presentation
      Leuven, Belgium
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] Polycomb-Mediated Epigenetic Silencing of miR-31 Activates NF-κ B Signalingin Adult T-cell Leukemia2011

    • Author(s)
      Yamagishi M, Nakano K, Yamochi T, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-14
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] A Novel Function of HTLV-1 Rex in Inhibition of the Host mRNA Surveillance Mechanism (NMD) for Protection of the Viral Genomic mRNA2011

    • Author(s)
      Nakano K, Ando T, Yamagishi M, Ishida T, Ohsugi T, Tanaka Y, Brighty D, Watanabe T
    • Organizer
      第4回HTLV-1研究会・合同班会議
    • Place of Presentation
      東京(東京大学弥生講堂)
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] 新規ATL型HeliosはIkaros転写因子ファミリーの機能を阻害し、T細胞の増殖を促進する2011

    • Author(s)
      浅沼里実,川波克明,山岸 誠,中野和民,山口一成,宇都宮 與,渡邉俊樹
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-23659484
  • [Presentation] 新規ATL型HeliosはIkaros転写因子ファミリーの機能を阻害し、T細胞の増殖を促進する。2011

    • Author(s)
      浅沼里実、川波克明、山岸誠、中野和民、山口一成、宇都宮與、渡邉俊樹
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Data Source
      KAKENHI-PROJECT-23659484
  • [Presentation] Polycomb依存的なエピジェネティック異常によるmiR-31の発現低下とNF-kB活性化機構2011

    • Author(s)
      山岸誠, 中野和民, 矢持忠徳, 宇都宮與, 山口一成, 内丸薫, 渡邉俊樹
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] A Novel Function of HTLV-1 Rex in Inhibition of the Host mRNA Surveillance Mechanism (NMD) for Protection of the Viral Genotnic mRNA2011

    • Author(s)
      Nakano K, Ando T, Yamagishi M, Ishida T, Ohsugi T, Tanaka Y, Brighty D, Watanabe T
    • Organizer
      The XXV Symposium of the International Association for Comparative Research on Leukemia and Related Diseases
    • Place of Presentation
      Tokyo(東京大学弥生講堂)
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] A Novel Function of HTLV-1 Rex in Inhibition of the Host mRNA Surveillance Mechanism(NMD) for Protection of the Viral Genomic mRNA2011

    • Author(s)
      Nakano K, Ando T, Yamagishi M, Ishida T, Ohsugi T, Tanaka Y, Brighty D, Watanabe T
    • Organizer
      The XXV Symposium of the International Association for Comparative Research on Leukemia and Related Diseases
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] Over-expression of dominant-negative Helios isoforms in adult T-cell leukemia (ATL) cells2011

    • Author(s)
      Asanuma S, Kawanami K, Nakano K,Yamagishi M, Yamaguchi K, Utsunomiya A, Watanabe T
    • Organizer
      The 15^th International Conference on Human Retrovirology: HTLV and Related Viruses
    • Place of Presentation
      Lueven, Belgium
    • Data Source
      KAKENHI-PROJECT-23659484
  • [Presentation] 新規ATL型HeliosはIkaros転写因子ファミリーの機能を阻害し、T細胞の増殖を促進する2011

    • Author(s)
      浅沼里実,川波克明,山岸誠,中野和民,山口一成,宇都宮與,渡邉俊樹
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23659484
  • [Presentation] A Novel Function of HTLV-1 Rex in Inhibition of the Host mRNA Surveillance Mechanism(NMD) for Protection of the Viral Genomic mRNA2011

    • Author(s)
      Nakano K, Ando T, Ishida T, Ohsugi T, Tanaka Y, Watanabe T
    • Organizer
      The 15th International Conference on Human Retrovirology : HTLV and Related Viruses
    • Place of Presentation
      Leuven, Belgium
    • Year and Date
      2011-06-05
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] Polycomb-Mediated Epigenetic Silencing of miR-31 Activates NF-κB Signaling in Adult T-cell Leukemia2011

    • Author(s)
      Yamagishi M, Nakano K, Yamochi T, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋国際会議場、名古屋
    • Year and Date
      2011-10-14
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] A Novel Function of HTLV-1 REX in Inhibition of the Host mRNA Surveillance Mechanism (NMD) for Protection of the Viral Genomic mRNA2011

    • Author(s)
      Nakano K, Ando T, Ishida T, Ohsugi T, Tanaka Y, Watanabe T
    • Organizer
      The XV International Congress of Virology
    • Place of Presentation
      Sapporo(札幌コンベンションセンター)
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] Novel Helios variants found in ATL cells hamper functions of Ikaros family proteins and induce T cell proliferation2011

    • Author(s)
      Asanuma S, Kawanami K, Yamagishi M, Nakano K, Yamaguchi K, Utsunomiya A, Watanabe T
    • Organizer
      The XXV Symposium of the International Association for Comparative Research on Leukemia and Related Diseases
    • Place of Presentation
      Yayoi Auditorium of Univ.Tokyo
    • Data Source
      KAKENHI-PROJECT-23659484
  • [Presentation] Genetic and Epigenetic Loss of miR-31 Activates NIK-dependent NF-κ B Pathway in Adult T-cell Leukemia2011

    • Author(s)
      Yamagisi M, Nakano K, Yamochi T, Miyake A, Kagami Y, Tsutsumi A, Otsubo A, Ogawa S, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      The 15th International Conference on Human Retrovirology : HTLV and Related Viruses
    • Place of Presentation
      Lueven, Belgium
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Over-expression of dominant-negative Helios isoforms in adult T-cell leukemia (ATL) cells2011

    • Author(s)
      Asanuma S, Kawanami K, Nakano K, Yamagishi M, Yamaguchi K, Utsunomiya A, Watanabe
    • Organizer
      The 15th International Conference on Human Retrovirology: HTLV and Related Viruses
    • Place of Presentation
      Lueven, Belgium
    • Data Source
      KAKENHI-PROJECT-23659484
  • [Presentation] 新規ATL型HeliosはIkaros転写因子ファミリーの機能を阻害し、T細胞の増殖を促進する2011

    • Author(s)
      浅沼里実、川波克明、山岸誠、中野和民、山口一成、宇都宮與、渡邉俊樹
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-23659484
  • [Presentation] A Novel Function of HTLV-1 Rex in Inhibition of the Host mRNA Surveillance Mechanism(NMD) for Protection of the Viral Genomic mRNA2011

    • Author(s)
      Nakano K, Ando T, Yamagishi M, Ishida T, Ohsugi T, Tanaka Y, Brighty D, Watanabe T
    • Organizer
      第4回HTLV-1研究会・合同班会議
    • Place of Presentation
      東京
    • Year and Date
      2011-09-19
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] Novel Helios variants found in ATL cells hamper functions of Ikaros family proteins and induce T cell proliferation2011

    • Author(s)
      Asanuma S, Kawanami K, Yamagishi M, Nakano K, Yamaguchi K, Utsunomiya A, Watanabe T
    • Organizer
      The XXV Symposium of the International Association for Comparative Research on Leukemia and Related Diseases
    • Place of Presentation
      東京大学弥生講堂(東京)
    • Data Source
      KAKENHI-PROJECT-23659484
  • [Presentation] Genetic and Epigenetic Loss of miR-31 Activates NIK-dependent NF-κB Pathway in Adult T-cell Leukemia2011

    • Author(s)
      Yamagisi M, Nakano K, Yamochi T, Miyake A, Kagami Y, Tsutsumi A, Otsubo A, Ogawa S, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      The 15^<th> International Conference on Huma Retrovirology : HTLV and Related Viruses
    • Place of Presentation
      Lueven, Belgium
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Polycomb依存的なエピジェネティック異常によるmiR-31の発現低下とNF-κB活性化機構2011

    • Author(s)
      山岸誠、中野和民、矢持忠徳、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場、名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Genetic and Epigenetic Loss of miR-31 Activates NIK-dependent NF-κB Pathway in Adult T-cell Leukemia2011

    • Author(s)
      Yamagishi M, Nakano K, Yamochi T, Miyake A, Kagami Y, Tsutsumi A, Matsubara A, Ogawa S, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      The XXV Symposium of the International Association for Comparative Research on Leukemia and Related Diseases
    • Place of Presentation
      Yayoi Auditorium, The University of Tokyo, Tokyo
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] 成人T細胞白血病に置けるHeliosのドミナントネガティブ型アイソフォームの過剰発現2010

    • Author(s)
      浅沼里実、中野和民、山岸誠、小川誠司、山口一成、宇都宮與、渡邉俊樹
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] 成人T細胞白血病(ATL)患者でのmicroRNA発現異常の実態2010

    • Author(s)
      中野和民、山岸 誠、三宅在子、加賀美弥生、包明久、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第50回日本リンパ網内系学会総会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL細胞におけるmiR-31発現低下によるNF-kBの恒常的活性化機構2010

    • Author(s)
      山岸誠、中野和民、三宅在子、矢持忠徳、加賀美弥生、包明久、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第50回日本リンパ網内系学会総会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Exploring biological significance of microRNA-451 up-regulation in ATL leukemo genesis2010

    • Author(s)
      Cai Y, Nakano K, Yamagishi M, Matsubara A, Kagami Y, Tsutsumi A, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL細胞におけるエピジェネティックな異常は、miR-31発現低下をしてNF-κBの恒常的活性化に寄与する2010

    • Author(s)
      山岸誠、中野和民、三宅在子、加賀美弥生、包明久、宇都宮與、山口一成、内丸薫、小川誠司、渡邉俊樹
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      徳島
    • Year and Date
      2010-11-08
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL細胞におけるエピジェネティックな異常によるmiR-31の発現低下とNF-κB活性化機構2010

    • Author(s)
      山岸誠, 中野和民、三宅在子、加賀美弥生、包明久、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] A Novel Function of HTLV-1 Rex in Inhibition of the Host NMD, the mRNA Surveillance Mechanism.2010

    • Author(s)
      Nakano K, Ando T, Ishida T, Ohsugi T, Tanaka Y, Watanabe T
    • Organizer
      Viruses, Genes, and Cancer
    • Place of Presentation
      Venice, Italy
    • Year and Date
      2010-09-30
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] A Novel Function of HTLV-1 Rex in Inhibition of the Host NMD, the mRNA Surveillance Mechanism2010

    • Author(s)
      Nakano K, Ando T, Ishida T, Ohsugi T, Tanaka Y, Watanabe T
    • Organizer
      Viruses, Genes ad Cancer-2010
    • Place of Presentation
      Venezia, Italy
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] HTLV-1 Rexの新しい機能:宿主Nonsense-Mediated mRNA Decay(NMD)の抑制2010

    • Author(s)
      Nakano K, Ando T, Ishida T, Ohsugi T, Tanaka Y, Watanabe T
    • Organizer
      日本ウィルス学会総会
    • Place of Presentation
      徳島
    • Year and Date
      2010-11-08
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] Loss of miR-31 links NF-κB activation in adult T-cell leukemia2010

    • Author(s)
      山岸誠, 中野和民, 三宅在子, 加賀美弥生, 包明久, 宇都宮與, 山口一成, 浅沼里実, 渡邉俊樹
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATLリスク・インァィケーター遺伝子同定の試みと、ATL発症における機能解析2010

    • Author(s)
      中野和民、松原亜以子、矢持忠徳、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Exploring biological significance of microRNA-451 up-regulation in ATL leukemogenesis2010

    • Author(s)
      Cai Y, Nakano K, Yamagishi M, Matsubara A, Kagami Y, Tsutsumi A, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Loss of miR-31 links NF-κB activation in Adult T-cell leukemia Viruses, Genes ad Cancer-20102010

    • Author(s)
      Yamagishi M, Nakano K, Miyake A, Kagami Y, Tsutsumi A, Utsunomiya A, Yamaguchi K, Uchimaru K, Watanabe T
    • Organizer
      Viruses, Genes and Cancer-2010
    • Place of Presentation
      Venezia, Italy
    • Year and Date
      2010-09-30
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Loss of miR-31 links NF-.B activation in Adult T-cell leukemia2010

    • Author(s)
      山岸誠, 中野和民, 三宅在子, 加賀美弥生, 包明久, 宇都宮與, 山口一成, 浅沼里実, 渡邉俊樹
    • Organizer
      Viruses, Genes and Cancer-2010
    • Place of Presentation
      Venezia, Italy
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Over-expression of dominant-negative Helios isoforms in adult T-cell leukemia (A TL) cells2010

    • Author(s)
      Asanuma S, Nakano K, Yamagishi M, Ogawa S, Yamaguchi K, Utsunomiya A, Watanabe T
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-02-09
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] A Novel Function of HTLV-1 Rex in Inhibition of the Host NMD, the mRNA Surveillance Mechanism2010

    • Author(s)
      中野和民
    • Organizer
      Viruses, Genes, and Cancer 2010
    • Place of Presentation
      Vienice, Italy
    • Year and Date
      2010-09-30
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] ATLリスク・インディケーター遺伝子同定の試みと、ATL発症における機能解析2010

    • Author(s)
      中野和民、松原亜以子、矢持忠徳、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Over-expression of dominant-nagative Helios isoforms in adult T-cell leukemia (ATL) cells2010

    • Author(s)
      浅沼里実, 中野和民, 山岸誠, 小川誠司, 山口一成, 宇都宮與, 渡邉俊樹
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] HTLV-1 Rexの新しい機能:宿主Nonsense-Mediated mRNA Decay(NMD)の抑制2010

    • Author(s)
      中野和民
    • Organizer
      日本ウイルス学会総会
    • Place of Presentation
      徳島 徳島県郷土文化会館(あわぎんホール)
    • Year and Date
      2010-11-08
    • Data Source
      KAKENHI-PROJECT-22700863
  • [Presentation] ATL細胞におけるエピジェネティックな異常は、miR-31発現低下を介してNF-κBの恒常的活性化に寄与する2010

    • Author(s)
      山岸誠、中野和民、三宅在子、加賀美弥生、包明久、宇都宮與、山口一成、内丸薫、小川誠司、渡邉俊樹
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] HTLV-1の自己複製と宿主mRNA品質管理機構(Nonsense-MediatedmRNA Decay : NMD)の攻防2009

    • Author(s)
      中野和民、安東友美、高橋隆太郎、石田尚臣、渡邉俊樹
    • Organizer
      第2回HTLV-1研究会・合同班会議
    • Place of Presentation
      東京大学医科学研究所
    • Year and Date
      2009-08-30
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Human T-Cell Leukemia Virus Tpe 1(HTLV-1)と宿主Nonsense-Mediated mRNA Decay(NMD)の攻防2009

    • Author(s)
      中野和民、安東友美、高橋隆太郎、石田尚臣、渡邉俊樹
    • Organizer
      第57回日本ウイルス学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-27
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] 植物アルカロイドセファランチンによる、HTLV-1感染細胞に対する抗腫瘍効果2009

    • Author(s)
      石渡優、矢持忠徳、山岸誠、中野和民、渡邉俊樹
    • Organizer
      第2回HTLV-1研究会・合同班会議
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Abnormal expression patterns of a lymphoid-specific transcriptional factor Helios in adult T-cell leukemia(ATL)cells2009

    • Author(s)
      浅沼里実、中野和民、山岸誠、山口一成、小川誠司、宇都宮與、渡邉俊樹
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] 成人T細胞白血病(ATL)での血球系特異的転写因子Heliosの発現異常2009

    • Author(s)
      浅沼里実、渡邉俊樹、中野和民、山岸誠、小川誠司、山口一成、宇都宮與
    • Organizer
      第2回HTLV-1研究会・合同班会議
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Potential Biomarker and Risk-Indicator Genes of ATL in Gene Expression Profiling of HTLV-1 Carriers2009

    • Author(s)
      中野和民、松原亜以子、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL患者でのマイクロアレイ技術を用いたマイクロRNA発現異常の解析2009

    • Author(s)
      三宅在子、山岸誠、中野和民、加賀美弥生、包明久、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL細胞におけるNMD機能不全の可能性の検討2009

    • Author(s)
      高橋隆太郎、安東友美、中野和民、宇都宮與、山口一成、渡邉俊樹
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL, HTLV-1感染細胞におけるEZH2の発現及び機能的解析2009

    • Author(s)
      山岸誠、黒川直也、副島あい、石田尚臣、中野和民、渡邉俊樹
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL細胞におけるmicroRNA発現異常の解析:miR-31の発現低下とNF-κBシグナル伝達系に及ぼす影響2009

    • Author(s)
      山岸誠、中野和民、三宅在子、加賀美弥生、包明久、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第2回HTLV-1研究会・合同班会議
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] 血球系特異的転写因子HeliosのATLにおける発現パターンの異常2009

    • Author(s)
      浅沼里実、渡邉俊樹、中野和民、山岸誠、小川誠司、山口一成、宇都宮與
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL,HTLV-1感染細胞におけるEZH2の発現及び機能的解析2009

    • Author(s)
      山岸誠、黒川直也、副島あい、石田尚臣、中野和民、渡邉俊樹
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] MicroRaNA Expression Profiling and Abnormal MicroRNA Expression in Adult T-Cell Leukemia2009

    • Author(s)
      山岸誠、三宅在子、中野和民、加賀美弥生、包明久、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL細胞におけるmicroRNA発現異常の解析:miR-31の発現低下とNF-κBシグナル伝達系に及ぼす影響2009

    • Author(s)
      山岸誠、中野和民、三宅在子、加賀美弥生、包明久、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第57回日本ウイルス学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-27
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Possible dysfunction of NMD in ATL cells2009

    • Author(s)
      Takahasi R, Ando T, Nakano K, Utsuno miva A, Yamaguchi K, Watanabe T
    • Organizer
      14th International Conference of Human Retrovirology : HTLV and related retroviruses
    • Place of Presentation
      Salvador, Brazil
    • Year and Date
      2009-07-02
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] HTLV-1キャリアの遺伝子発現プロファイリングによるATLバイオマーカー遺伝子とリスク・インディケーター遺伝子同定の試み2009

    • Author(s)
      中野和民、松原亜以子、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ビスコクラウリン型アルカイド製剤セファランチンによる、HTLV-1感染細胞に対する細胞毒性効果2009

    • Author(s)
      石渡優、矢持忠徳、山岸誠、中野和民、渡邉俊樹
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL患者におけるmicroRNA発現異常の解析:miR-31の発現低下がNIKおよびNF-κBシグナル伝達系に及ぼす影響2009

    • Author(s)
      中野和民、山岸誠、三宅在子、加賀美弥生、包明久、宇都宮與、山口一成、内丸薫、渡邉俊樹
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] Abnormal expression patterns of a lymphoid-specific transcriptional factor Helios in adult T-cell leukemia(ATL) cells2009

    • Author(s)
      浅沼里実、中野和民、山岸誠、山口一成、小川誠司、宇都宮與、渡邉俊樹
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL型発現スコアによるATL発症ハイリスクHTLV-1キャリアの同定2008

    • Author(s)
      加賀美弥生, 松原亜以子、正田桃子、中野和民、岩永正子、渡辺慎哉、宇都宮與、東條有伸、山口一成、渡邉俊樹
    • Organizer
      第1回HTLV-1研究会・合同班会議
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATLにおける遺伝子発現レベルおよびゲノムコピーナンバー異常の相関解析による網羅的遺伝子プロファイリング2008

    • Author(s)
      中野和民、松原亜以子、武藤早紀、加藤元博、滝田順子、宇都宮與、山口一成、山田恭輝、大島孝一、小川誠司、渡邉俊樹
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL細胞及びHTLV-1感染細胞株のmiRNAプロフィール2008

    • Author(s)
      包明久、加賀美弥生、吉田エリカ、松原亜以子、中野和民、渡邉俊樹
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] ATL細胞におけるヒトmiRNAの発現プロフィール解析2008

    • Author(s)
      包明久、加賀美弥生, 中野和民、松原亜以子、渡邉俊樹
    • Organizer
      第1回HTLV-1研究会・合同班会議
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-20390267
  • [Presentation] 成人T細胞白血病におけるEZH2依存的エピジェネティック異常の包括的解析

    • Author(s)
      堀真琴、藤川大、中川翔太、田中勇悦、中野和民、渡邉俊樹、山岸誠
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] miRNA signature and its functional involvement in aggressiveness of diffuse large B cell lymphoma

    • Author(s)
      Yamagishi M, Katano H, Nakano K, Ota Y, Hishima T, Okada S, Watanabe T
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都国際会議場
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Aberrrantly spliced Helios variants in ATL cells induce T cell proliferation

    • Author(s)
      Asanuma S, Nakano K, Yamagishi M, Ogawa S, Yamaguchi K, Utsunomiya A, Watanabe T
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都国際会議場
    • Data Source
      KAKENHI-PROJECT-23659484
  • [Presentation] ATL細胞におけるEZH2依存的エピジェネティック異常の包括的解析

    • Author(s)
      藤川大、山岸誠、黒川直也、副島あい、中川翔太、石田尚臣、田中勇悦、中野和民、渡邉俊樹
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所、 東京
    • Year and Date
      2014-08-22 – 2014-08-24
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] Tumor-specific gene expression leads to p38 and Hedgehog signaling activation in adult T cell leukemia

    • Author(s)
      Yamagishi M, Takahashi R, Sakai N, Fujikawa D, Nakagawa S, Yamochi T, Yamochi T, Nakano K, Uchimaru K, Utsunomiya A, Watanabe T
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場、大阪
    • Year and Date
      2014-10-31 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] 鎖抗体(scFv)を用いたHTLV-1感染細胞特異的miRNA輸送システムの構築

    • Author(s)
      西田亜季、長門石曉、中野和民、山岸誠、矢持忠徳、田中勇悦、津本浩平、渡邉俊樹
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所、 東京
    • Year and Date
      2014-08-22 – 2014-08-24
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] ATL細胞におけるEZH2依存的エピジェネティック異常の包括的解析

    • Author(s)
      藤川大、山岸誠、中川翔太、黒川直也、副島あい、石田尚臣、田中勇悦、中野和民、渡邉俊樹
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2014-10-31 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] HTLV-1タンパク質TaxはPolycombタンパク質EZH2との相互作用を介してエピジェネティクスの脱制御を誘導する

    • Author(s)
      藤川 大、山岸誠、黒川直也、副島あい、石田尚臣、中野和民、渡邉俊樹
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] Molecular hallmarks of adult T cell leukemia: miRNA epigenetics and emerging signaling abnormalities

    • Author(s)
      Yamagishi M, Takahashi R, Nakano K, Asanuma S, Utsunomiya A, Yamaguchi K, Uchimaru K, Ogawa S, Watanabe T
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都国際会議場
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] HTLV-1タンパク質TaxとPolycombタンパク質との新規相互作用がT細胞に与える影響の解析

    • Author(s)
      藤川 大、山岸 誠、黒川直也、副島あい、石田尚臣、中野和民、渡邉俊樹
    • Organizer
      第5回HTLV-1研究会・シンポジウム
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-23390250
  • [Presentation] ETV6/FLT3 fusion is a novel client protein of hsp90

    • Author(s)
      Bui TK Ly, Hoang T Chi, Yuko Sato, Phan T Xinh, Nakano K, Watanabe T
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場、大阪
    • Year and Date
      2014-10-31 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-24501304
  • [Presentation] 成人T細胞白血病(ATL)における新規TIAM2変異体の同定と遺伝子発現異常の解析

    • Author(s)
      笹島悟史、中野和民、内丸 薫、渡邉俊樹
    • Organizer
      第5回HTLV-1研究会・シンポジウム
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-23659484
  • 1.  WATANABE Toshiki (30182934)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  UCHIMARU Kaoru (60251203)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 50 results
  • 3.  TSUKASAKI Kunihiro (40274659)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  ISHIDA Takaomi (80293447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 5.  矢持 忠徳 (80306844)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  山岸 誠 (90625261)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 17 results
  • 7.  佐藤 知雄 (30387063)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  鴨居 功樹 (40451942)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  宇都宮 與 (40511663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  田部 亜季 (60786367)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 11.  渡辺 俊樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 137 results
  • 12.  大杉 剛生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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