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Mogushi Kaoru  茂櫛 薫

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… Alternative Names

MOGUSHI Kaoru  茂櫛 薫

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Researcher Number 60569292
Other IDs
Affiliation (Current) 2025: 順天堂大学, 大学院医学研究科, 非常勤講師
2025: 東京科学大学, 医療・創薬イノベーション教育開発機構, 特任教授
Affiliation (based on the past Project Information) *help 2021 – 2022: 順天堂大学, 大学院医学研究科, 非常勤講師
2018 – 2020: 順天堂大学, 医学(系)研究科(研究院), 非常勤講師
2017: 順天堂大学, 医学(系)研究科(研究院), 講師
2014 – 2016: 順天堂大学, 医学(系)研究科(研究院), 助教
2015: 順天堂大学大学院医学系研究科ゲノム, 再生医療センター, 助教
2014: 順天堂大学, 医学(系)研究科, 助教
2013: 東京医科歯科大学, 難治疾患研究所, 非常勤講師
Review Section/Research Field
Principal Investigator
Basic Section 43060:System genome science-related / Tumor therapeutics
Except Principal Investigator
Digestive surgery / Respiratory organ internal medicine / Basic Section 55040:Respiratory surgery-related / Basic Section 53030:Respiratory medicine-related / Surgical dentistry / General surgery / Medical genome science / Gastroenterology
Keywords
Principal Investigator
バイオインフォマティクス / 遺伝子発現解析 / 遺伝子発現情報 / 臨床検体 / 仮想ダイセクション / 教師なし学習 / 仮想ダイセクション法 / マイクロアレイ / シグナル伝達 / 多変量解析 / 部分最小二乗回帰 / 肝細胞癌 … More
Except Principal Investigator
… More 大腸癌 / 腫瘍マーカー / 大腸がん / CAGE法 / 癌 / 転移予測マーカー / 新規治療標的 / 遺伝子解析 / スクリーニング解析 / チロシンキナーゼ / 遺伝子異常 / 再発予測マーカー / バイオマーカー / 網羅的解析 / microRNA / マーカー / CAGE / 採血 / 転移マーカー / 肺転移 / 胸腺癌 / 転移メカニズム / マイクロダイセクション / 採血診断 / 癌遺伝子 / 肝転移 / スクリーニング / 分子標的 / 分子標的治療薬 / 小細胞肺癌 / トランスレーショナルリサーチ / 遺伝子 / 網羅的発現解析 / 次世代シークエンサー / 次世代シークセンサー / リンパ節転移 / ヒストンメチル化酵素 / 中皮腫 / エピジェネティクス / ヒストン脱メチル化酵素 / 小細胞肺がん / 中皮腫久 / LSD1 / ヒストン脱メチル化 / ヒストンメチル化 / ヒストン修飾 / エピジェンティクス / 肺がん / 転移 / 不均一性 / 悪性腫瘍 / ゲノム / 口腔 / 腫瘍内不均一性 / 個別化 / 血中循環腫瘍DNA / 個別化マーカー / 再発 / 血中循環腫瘍DNA / リキッドバイオプシー / 腫瘍メーカー / 治療効果判定 / CAGE解析 / 血中RNA / マイクロRNA / 抗がん剤感受性 / 遺伝子ネットワーク / 肝細胞癌 / がんパスウェイ / ARACNe / Waddington地形 / 遺伝子発現プロファイル / がん転移 / 上皮間葉転換 / siRNA / mRNA / 網羅的遺伝子発現解析 / 肝腫瘍原性遺伝子 / 酸化ストレス / 肝発癌 Less
  • Research Projects

    (13 results)
  • Research Products

    (47 results)
  • Co-Researchers

    (30 People)
  •  Development and its application of the "virtual dissection" method using gene expression profiles of clinical specimensPrincipal Investigator

    • Principal Investigator
      Mogushi Kaoru
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43060:System genome science-related
    • Research Institution
      Juntendo University
  •  analysis of novel transcript variant of tyrosine kinase gene in thymic carcinoma

    • Principal Investigator
      Takahashi Kazuhisa
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Juntendo University
  •  Identification of lung metastasis predictive marker for colorectal cancer with gene explession analysis using CAGE

    • Principal Investigator
      Yaginuma Yukihiro
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Juntendo University
  •  analysis of novel transcript variant of tyrosine kinase gene in small cell lung cancer using the NanoString nCounter

    • Principal Investigator
      Takahashi Fumiyuki
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Juntendo University
  •  Identification of biomaker for predicting liver metastasis of colorectal cancer with CAGE analysis

    • Principal Investigator
      Hiromitsu Komiayama
    • Project Period (FY)
      2017 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Juntendo University
  •  Inactivation of tumor suppressor by histone methylation in lung cancer

    • Principal Investigator
      Tajima Ken
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Juntendo University
  •  Development of biomarker for detection of lymphnode metastasis and prediction of recurrence in colorectal cancer using CAGE analysis

    • Principal Investigator
      Okuzawa Atsushi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Juntendo University
  •  Searching for miRNA as a biomarker in blood colorectal cancer in blood to evaluate sensitivities against chemotherapies for colorectal cancer

    • Principal Investigator
      TAKAHSHI Makoto
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Juntendo University
  •  Construction of personalized monitoring system for colorectal caner using circulating tumor DNA

    • Principal Investigator
      KAMIYAMA HIROHIKO
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Juntendo University
  •  Study on formation and evaluation method of intratumoral heterogeneity in oral cancer

    • Principal Investigator
      UZAWA NARIKAZU
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Osaka University
      Tokyo Medical and Dental University
  •  System-based drug discovery database using partial least square regressionPrincipal Investigator

    • Principal Investigator
      MOGUSHI Kaoru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Juntendo University
  •  Identification and clinical application of pathway-based markers for cancer

    • Principal Investigator
      Tanaka Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical genome science
    • Research Institution
      Tokyo Medical and Dental University
  •  Functional analysis of oxidative stress-induced hepatocarcinogenic genes for molecular target treatment

    • Principal Investigator
      TSUBOTA Akihito
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Jikei University School of Medicine

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Other

  • [Journal Article] Biological and Clinicopathological Implications of Beta-3-N-acetylglucosaminyltransferase 8 in Triple-negative Breast Cancer2021

    • Author(s)
      OKAZAKI MISATO、MOGUSHI KAORU、DENDA-NAGAI KAORI、FUJIHIRA HARUHIKO、NOJI MIKI、ISHII-SCHRADE KATRIN、SAKATA-MATSUZAWA MADOKA、NAKAI KATSUYA、HORIMOTO YOSHIYA、SAITO MITSUE、IRIMURA TATSURO
    • Journal Title

      Anticancer Research

      Volume: 41 Issue: 2 Pages: 845-858

    • DOI

      10.21873/anticanres.14837

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07163, KAKENHI-PROJECT-18K06198
  • [Journal Article] A novel diagnostic system to evaluate epidermal growth factor receptor impact as a prognostic and therapeutic indicator for lung adenocarcinoma2020

    • Author(s)
      Takakuwa Kazuya、Mogushi Kaoru、Han Min、Fujii Tomoaki、Hosoya Masaki、Yamanami Arina、Akita Tomomi、Yamashita Chikamasa、Hayashida Tetsu、Kato Shunsuke、Yamaguchi Shigeo
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 6214-6214

    • DOI

      10.1038/s41598-020-63200-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10558, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-19K07740, KAKENHI-PROJECT-18K14961
  • [Journal Article] Short somatic alterations at the site of copy number variation in breast cancer2020

    • Author(s)
      Murakami Fumi、Tsuboi Yumi、Takahashi Yuka、Horimoto Yoshiya、Mogushi Kaoru、Ito Takeshi、Emi Mitsuru、Matsubara Daisuke、Shibata Tatsuhiro、Saito Mitsue、Murakami Yoshinori
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 1 Pages: 444-453

    • DOI

      10.1111/cas.14630

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-20K21539, KAKENHI-PROJECT-20H03525
  • [Journal Article] Comprehensive molecular characterization of liver cancer and inheritance of the phenotypic traits during tumor recurrence.2019

    • Author(s)
      Shimada S, Mogushi K, Akiyama Y, Furuyama T, Watanabe S, Ogura T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Tanabe M, Wands JR, Tanaka S.
    • Journal Title

      EBioMedicine

      Volume: 40 Pages: 457-470

    • DOI

      10.1016/j.ebiom.2018.12.058

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-16H02670
  • [Journal Article] Identification of genes and pathways, including the CXCL2 axis, altered by DNA methylation in hepatocellular carcinoma.2019

    • Author(s)
      Subat S, Mogushi K, Yasen M, Kohda T, Ishikawa Y, Tanaka H.
    • Journal Title

      Journal of cancer research and clinical oncology

      Volume: 145(3) Issue: 3 Pages: 675-684

    • DOI

      10.1007/s00432-018-2824-0

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08798
  • [Journal Article] Glucose metabolism changes during the development and progression of oral tongue squamous cell carcinomas2019

    • Author(s)
      Nakazato K, Mogushi K, Kayamori K, Tsuchiya M, Takahashi KI, Sumino J, Michi Y, Yoda T, Uzawa N.
    • Journal Title

      Oncology Letters

      Volume: 18 Pages: 1372-1380

    • DOI

      10.3892/ol.2019.10420

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06198
  • [Journal Article] Idebenone has preventative and therapeutic effects on pulmonary fibrosis via preferential suppression of fibroblast activity2019

    • Author(s)
      Sugizaki T, Tanaka KI, Asano T, Kobayashi D, Hino Y, Takafuji A, Shimoda M, Mogushi K, Kawahara M, Mizushima T.
    • Journal Title

      Cell Death Discovery

      Volume: 5 Issue: 1 Pages: 146-146

    • DOI

      10.1038/s41420-019-0226-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06198
  • [Journal Article] Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism.2019

    • Author(s)
      Nakayama S, Shimonaka S, Elahi M, Nishioka K, Oji Y, Matsumoto SE, Li Y, Yoshino H, Mogushi K, Hatano T, Sato T, Ikura T, Ito N, Motoi Y, Hattori N.
    • Journal Title

      Neurobiology of Aging

      Volume: 19 Pages: 240.e13-240.e22

    • DOI

      10.1016/j.neurobiolaging.2019.02.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09678, KAKENHI-PROJECT-18K06198
  • [Journal Article] Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome.2019

    • Author(s)
      Borna NN, Kishita Y, Kohda M, Lim SC, Shimura M, Wu Y, Mogushi K, Yatsuka Y, Harashima H, Hisatomi Y, Fushimi T, Ichimoto K, Murayama K, Ohtake A, Okazaki Y.
    • Journal Title

      Neurogenetics

      Volume: 20(1) Issue: 1 Pages: 9-25

    • DOI

      10.1007/s10048-018-0561-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-17F17714, KAKENHI-PROJECT-16K09973
  • [Journal Article] Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity.2019

    • Author(s)
      Matsumura Y, Ito Y, Mezawa Y, Sulidan K, Daigo Y, Hiraga T, Mogushi K, Wali N, Suzuki H, Itoh T, Miyagi Y, Yokose T, Shimizu S, Takano A, Terao Y, Saeki H, Ozawa M, Abe M, Takeda S, Okumura K, Habu S, Hino O, Takeda K, Hamada M, Orimo A.
    • Journal Title

      Life Sci Alliance

      Volume: 2(4):e201900425. Issue: 4 Pages: 1-24

    • DOI

      10.26508/lsa.201900425

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K07207, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-19K07884, KAKENHI-PROJECT-18K19656, KAKENHI-PROJECT-18H02695, KAKENHI-PROJECT-19H03559, KAKENHI-PROJECT-18K19483, KAKENHI-PROJECT-19K21278, KAKENHI-PROJECT-16H05879, KAKENHI-PROJECT-16H06277
  • [Journal Article] Estrogen receptor-positive ductal carcinoma in situ frequently overexpresses HER2 protein without gene amplification.2019

    • Author(s)
      Horimoto Y, Terao T, Tsutsumi Y, Tanabe M, Mogushi K, Hlaing MT, Sasaki R, Saeki H, Okazaki M, Sonoue H, Arakawa A, Saito M.
    • Journal Title

      Am J Surg Pathol

      Volume: 43(9) Issue: 9 Pages: 1221-1228

    • DOI

      10.1097/pas.0000000000001300

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K16287
  • [Journal Article] Elucidation of inhibitory effects on metastatic sentinel lymph nodes of breast cancer during One-Step Nucleic Acid Amplification.2018

    • Author(s)
      Horimoto Y, Tanabe M, Kazuno S, Miura Y, Mogushi K, Sonoue H, Arakawa A, Kajino K, Kobayashi T, Saito M.
    • Journal Title

      Sci Rep

      Volume: 8(1):7563 Issue: 1 Pages: 1-7

    • DOI

      10.1038/s41598-018-25911-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798
  • [Journal Article] Tumor sidedness and enriched gene groups for efficacy of first-line cetuximab treatment in metastatic colorectal cancer.2018

    • Author(s)
      Sunakawa Y, Mogushi K, Lenz HJ, Zhang W, Tsuji A, Takahashi T, Denda T, Shimada K, Kochi M, Nakamura M, Kotaka M, Ichikawa W. et al
    • Journal Title

      Molecular Cancer Therapeutics

      Volume: 17(12) Pages: 2788-2795

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08798
  • [Journal Article] Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors2018

    • Author(s)
      Chiyonobu Norimichi、Shimada Shu、Akiyama Yoshimitsu、Mogushi Kaoru、Itoh Michiko、Akahoshi Keiichi、Matsumura Satoshi、Ogawa Kosuke、Ono Hiroaki、Mitsunori Yusuke、Ban Daisuke、Kudo Atsushi、Arii Shigeki、Suganami Takayoshi、Yamaoka Shoji、Ogawa Yoshihiro、Tanabe Minoru、Tanaka Shinji
    • Journal Title

      Am. J. Pathol.

      Volume: 188 Issue: 5 Pages: 1213-1224

    • DOI

      10.1016/j.ajpath.2018.01.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0110, KAKENHI-PROJECT-16K08732, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16H05171, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K19575, KAKENHI-PUBLICLY-17H05500
  • [Journal Article] KCTD12 is negatively regulated by Kit in gastrointestinal stromal tumors.2018

    • Author(s)
      Suehara Y, Akaike K, Mukaihara K, Kurisaki-Arakawa A, Kubota D, Okubo T, Mitomi H, Mitani K, Takahashi M, Toda-Ishii M1, Kim Y, Tanabe Y, Takagi T, Hayashi T, Mogushi K, Kaneko K, Yao T, Saito T.
    • Journal Title

      Oncotarget

      Volume: 9(43) Issue: 43 Pages: 27016-27026

    • DOI

      10.18632/oncotarget.25469

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K15329, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070
  • [Journal Article] Tumor Sidedness and Enriched Gene Groups for Efficacy of First-line Cetuximab Treatment in Metastatic Colorectal Cancer.2018

    • Author(s)
      Sunakawa Y, Mogushi K, Lenz HJ, Zhang W, Tsuji A, Takahashi T, Denda T, Shimada K, Kochi M, Nakamura M, Kotaka M, Segawa Y, Tanioka H, Negoro Y, Moran M, Astrow SH, Hsiang J, Stephens C, Fujii M, Ichikawa W.
    • Journal Title

      Mol Cancer Ther.

      Volume: 17 Issue: 12 Pages: 2788-2795

    • DOI

      10.1158/1535-7163.mct-18-0694

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09333, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-18K06198
  • [Journal Article] GCH1 mutations in dopa-responsive dystonia and Parkinson's disease.2018

    • Author(s)
      Yoshino H, Nishioka K, Li Y, Oji Y, Oyama G, Hatano T, Machida Y, Shimo Y, Hayashida A, Ikeda A, Mogushi K, Shibagaki Y, Hosaka A, Iwanaga H, Fujitake J, Ohi T, Miyazaki D, Sekijima Y, Oki M, Kusaka H, Fujimoto KI Ugawa Y, Funayama M, Hattori N.
    • Journal Title

      Journal of Neurology

      Volume: 265(8) Issue: 8 Pages: 1860-1870

    • DOI

      10.1007/s00415-018-8930-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09676, KAKENHI-PROJECT-16K09678, KAKENHI-PROJECT-16K09700
  • [Journal Article] Tumor suppressor functions of DAXX through histone H3.3/H3K9me3 pathway in pancreatic NETs.2018

    • Author(s)
      Ueda H, Akiyama Y, Shimada S, Mogushi K, Serizawa M, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S.
    • Journal Title

      Endocr Relat Cancer

      Volume: 25(6) Issue: 6 Pages: 619-631

    • DOI

      10.1530/erc-17-0328

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10653, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-15H04926
  • [Journal Article] COQ2 variants in Parkinson's disease and multiple system atrophy.2018

    • Author(s)
      Mikasa M, Kanai K, Li Y, Yoshino H, Mogushi K, Hayashida A, Ikeda A, Kawajiri S, Okuma Y, Kashihara K, Sato T, Kondo H, Funayama M, Nishioka K, Hattori N.
    • Journal Title

      J Neural Transm (Vienna)

      Volume: - Issue: 6 Pages: 938-944

    • DOI

      10.1007/s00702-018-1885-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09676, KAKENHI-PROJECT-26461319, KAKENHI-PROJECT-15KK0354, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K09811, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-16K09678, KAKENHI-PROJECT-16K09700, KAKENHI-PROJECT-20K18340
  • [Journal Article] Non-small cell lung carcinoma with diffuse co-expression of thyroid transcription factor-1 and ΔNp63/p402018

    • Author(s)
      Hayashi Takuo、Takamochi Kazuya、Yanai Yuka、Mitani Keiko、Tomita Hisashi、Mogushi Kaoru、Suehara Yoshiyuki、Takahashi Fumiyuki、Suzuki Kenji、Saito Tsuyoshi、Yao Takashi
    • Journal Title

      Human Pathology

      Volume: S0046-8177 Pages: 30037-6

    • DOI

      10.1016/j.humpath.2018.01.023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26461200, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-18K08798
  • [Journal Article] Molecular and clinical features of the TP53 signature gene expression profile in early-stage breast cancer.2018

    • Author(s)
      Yamaguchi S, Takahashi S, Mogushi K, Izumi Y, Nozaki Y, Nomizu T, Kakugawa Y, Ishida T, Ohuchi N, Ishioka C, Kato S.
    • Journal Title

      Oncotarget

      Volume: 9(18) Issue: 18 Pages: 14193-14206

    • DOI

      10.18632/oncotarget.24447

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-15K06851, KAKENHI-PROJECT-15K10081, KAKENHI-PROJECT-16K11029
  • [Journal Article] ARID2 modulates DNA damage response in human hepatocellular carcinoma cells.2017

    • Author(s)
      Oba A, Shimada S, Akiyama Y, Nishikawaji T, Mogushi K, Ito H, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Asahara H, Kaida A, Miura M, Tanabe M, Tanaka S.
    • Journal Title

      Journal of Hepatology

      Volume: in press Issue: 5 Pages: 942-951

    • DOI

      10.1016/j.jhep.2016.12.026

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10421, KAKENHI-PROJECT-17K10653, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15H04926
  • [Journal Article] Clinical significance of methylation and reduced expression of the quaking gene in colorectal cancer2017

    • Author(s)
      Iwata N, Ishikawa T, Okazaki S, Mogushi K, Baba H, Ishiguro M, Kobayashi H, Tanaka H, Kawano T, Sugihara K, Uetake H.
    • Journal Title

      Anticancer Res

      Volume: 37(2) Issue: 2 Pages: 489-498

    • DOI

      10.21873/anticanres.11341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10552
  • [Journal Article] Promoter-level transcriptome in primary lesions of endometrial cancer identified biomarkers associated with lymph node metastasis.2017

    • Author(s)
      Yoshida E, Terao Y, Hayashi N, Mogushi K, Arakawa A, Tanaka Y, Ito Y, Ohmiya H, Hayashizaki Y, Takeda S, Itoh M, Kawaji H.
    • Journal Title

      Sci Rep

      Volume: 7(1):14160 Issue: 1 Pages: 1-15

    • DOI

      10.1038/s41598-017-14418-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-15K10732, KAKENHI-PROJECT-16K15334
  • [Journal Article] Acquired resistance with epigenetic alterations under long-term anti-angiogenic therapy for hepatocellular carcinoma.2017

    • Author(s)
      Ohata Y, Akiyama Y, Shimada S, Mogushi K, Nakao K, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S.
    • Journal Title

      Molecular Cancer Therapeutics

      Volume: in press Issue: 6 Pages: 1155-1165

    • DOI

      10.1158/1535-7163.mct-16-0728

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10421, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670
  • [Journal Article] LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer2017

    • Author(s)
      Jotatsu, T., Yagishita, S., Tajima, K., Takahashi, F., Mogushi, K., Hidayat, M., Wirawan, A., Ko, R., Kanemaru, R., Shimada, N., Mitani, K., Saito, T., Takamochi, K., Suzuki, K., Kohsaka, S., Kojima, S., Mukae, H., Yatera, K., and Takahashi, K.
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 9 Pages: 86-94

    • DOI

      10.1016/j.bbrep.2016.11.015

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09586, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15625
  • [Journal Article] Correlation of EGFR or KRAS mutation status with 18F-FDG uptake on PET-CT scan in lung adenocarcinoma.2017

    • Author(s)
      Takamochi K, Mogushi K, Kawaji H, Imashimizu K, Fukui M, Oh S, Itoh M, Hayashizaki Y, Ko W, Akeboshi M, Suzuki K.
    • Journal Title

      PLoS One

      Volume: 12(4):e0175622. Issue: 4 Pages: e0175622-e0175622

    • DOI

      10.1371/journal.pone.0175622

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10035
  • [Journal Article] CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells.2016

    • Author(s)
      Katsuta, E., Tanaka, S., Mogushi, K., Shimada, S., Akiyama, Y., Aihara, A., Matsumura, S., Mitsunori, Y., Ban, D., Ochiai, T., Kudo, A., Fukamachi, H., Tanaka, H., Nakayama, K., Arii, S., Tanabe, M.
    • Journal Title

      Int. J. Oncol.

      Volume: 48 Issue: 2 Pages: 657-669

    • DOI

      10.3892/ijo.2015.3299

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06832, KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25462082, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-26462025
  • [Journal Article] Novel biomarkers that assist in accurate discrimination of squamous cell carcinoma from adenocarcinoma of the lung2016

    • Author(s)
      Kazuya Takamochi, Hiroko Ohmiya, Masayoshi Itoh, Kaoru Mogushi, Tsuyoshi Saito, Kieko Hara, Keiko Mitani, Yasushi Kogo, Yasunari Yamanaka, Jun Kawai, Yoshihide Hayashizaki, Shiaki Oh, Kenji Suzuki, Hideya Kawaji
    • Journal Title

      BMC cancer

      Volume: 16:760 Pages: 1-10

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10552
  • [Journal Article] CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells.2016

    • Author(s)
      Katsuta E, Tanaka S, Mogushi K, Shimada S, Akiyama Y, Aihara A, Matsumura S, Mitsunori Y, Ban D, Ochiai T, Kudo A, Fukamachi H, Tanaka H, Nakayama K, Arii S, Tanabe M.
    • Journal Title

      International Journal of Oncology

      Volume: 48 Issue: 9 Pages: 657-69

    • DOI

      10.1007/s00535-015-1159-8

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-26870175
  • [Journal Article] Characterizing Genetic Transitions of Copy Number Alterations and Allelic Imbalances in Oral Tongue Carcinoma Metastasis2016

    • Author(s)
      Morita T, Uzawa N, Mogushi K, Sumino J, Michikawa C, Takahashi KI, Myo K, Izumo T, Harada K
    • Journal Title

      Genes Chromosomes Cancer

      Volume: 55 Issue: 12 Pages: 975-986

    • DOI

      10.1002/gcc.22395

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25861913, KAKENHI-PROJECT-26861704, KAKENHI-PROJECT-26861705, KAKENHI-PROJECT-15K11288
  • [Journal Article] Overexpression of the S100A2 protein as a prognostic marker for patients with stage II and III colorectal cancer.2016

    • Author(s)
      Masuda T, Ishikawa T, Mogushi K, Okazaki S, Ishiguro M, Iida S, Mizushima H, Tanaka H, Uetake H, Sugihara K.
    • Journal Title

      Int J Oncol. 2016 Mar;48(3):975-82..

      Volume: 48(3) Issue: 3 Pages: 975-982

    • DOI

      10.3892/ijo.2016.3329

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10035
  • [Journal Article] Loss of MyD88 alters neuroinflammatory response and attenuates early Purkinje cell loss in a spinocerebellar ataxia type 6 mouse model2015

    • Author(s)
      Aikawa T, Mogushi K, Iijima-Tsutsui K, Ishikawa K, Sakurai H, Tanaka H, Mizusawa H, Watase K
    • Journal Title

      Human molecular genetics

      Volume: 24(17) Issue: 17 Pages: 4780-4791

    • DOI

      10.1093/hmg/ddv202

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-26860661, KAKENHI-PROJECT-25282241
  • [Journal Article] CHCHD2 mutations in autosomal dominant late-onset Parkinson’s disease: a genome-wide linkage and sequencing study.2015

    • Author(s)
      Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Yuanzhe L, Ogaki K, Ando M, Yoshinon H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N.
    • Journal Title

      Lancet Neurol

      Volume: 14 Issue: 3 Pages: 274-282

    • DOI

      10.1016/s1474-4422(14)70266-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-24390224, KAKENHI-PROJECT-24500868, KAKENHI-PROJECT-24790903, KAKENHI-PUBLICLY-25110720, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111007, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25461291, KAKENHI-PROJECT-25461292, KAKENHI-PROJECT-25670420, KAKENHI-PROJECT-25713015, KAKENHI-PROJECT-25860725, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-15K10050, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-25257507, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-25305030
  • [Journal Article] Prognostic significance of Traf2-and Nck- interacting kinase (TNIK) in colorectal cancer.2015

    • Author(s)
      Takahashi H, Ishikawa T, Ishiguro M, Okazaki S, Mogushi K, Kobayashi H, Iida S, Mizushima H, Tanaka H, Uetake H, Sugihara K.
    • Journal Title

      BMC Cancer

      Volume: 15 Issue: 1 Pages: 794-794

    • DOI

      10.1186/s12885-015-1783-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26870175
  • [Journal Article] Distinct clinicopathological phenotype of hepatocellular carcinoma with EOB-MRI hyperintensity: association with gene expression signature2015

    • Author(s)
      Miura T, Ban D, Tanaka S, Mogushi K, Kudo A, Matsumura S, Mitsunori Y, Ochiai T, Tanaka H, Tanabe M.
    • Journal Title

      Am J Surg.

      Volume: 210 Issue: 3 Pages: 561-569

    • DOI

      10.1016/j.amjsurg.2015.03.027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25462082
  • [Journal Article] Mitochondrial metabolism in the noncancerous liver determine the occurrence of hepatocellular carcinoma: a prospective study.2014

    • Author(s)
      Kudo A, Mogushi K, Takayama T, Matsumura S, Ban D, Irie T, Ochiai T, Nakamura N, Tanaka H, Anzai N, Sakamoto M, Tanaka S, Arii S.
    • Journal Title

      J Gastroenterol.

      Volume: 49 Issue: 3 Pages: 502-10

    • DOI

      10.1007/s00535-013-0791-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591868, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-25290070, KAKENHI-PROJECT-26870175
  • [Journal Article] Involvement of MAP3K8 and miR-17-5p in poor virologic response to interferon-based combination therapy for chronic hepatitis C2014

    • Author(s)
      Tsubota A, Mogushi K, Aizaki H, Miyaguchi K, Nagatsuma K, Matsudaira H, Kushida T, Furihata T, Tanaka H, Matsuura T.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 5 Pages: e97078-e97078

    • DOI

      10.1371/journal.pone.0097078

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-24591001, KAKENHI-PROJECT-26870175
  • [Journal Article] Age-related clinicopathological and molecular features of patients received curative hepatectomy for hepatocellular carcinoma.2014

    • Author(s)
      Katsuta E, Tanaka S, Mogushi K, Matsumura S, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Tanaka H, Tanabe M, Arii S.
    • Journal Title

      American Journal of Surgery

      Volume: 208(3) Issue: 3 Pages: 450-456

    • DOI

      10.1016/j.amjsurg.2014.01.015

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22130005, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-25290070, KAKENHI-PROJECT-26870175
  • [Journal Article] Visualization of stem cell features in human hepatocellular carcinoma enlightened in vivo significance of tumor-host interaction and clinical implication.2013

    • Author(s)
      Muramatsu S
    • Journal Title

      Hepatology

      Volume: 58 Issue: 1 Pages: 218-228

    • DOI

      10.1002/hep.26345

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130005, KAKENHI-PROJECT-22249050, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-25290070, KAKENHI-PLANNED-22117004
  • [Journal Article] Contrast-enhanced intraoperative ultrasonography for vascular imaging of hepatocellular carcinoma; clinical and biological significance.2013

    • Author(s)
      Sato K
    • Journal Title

      Hepatology

      Volume: 57 Issue: 4 Pages: 1436-1447

    • DOI

      10.1002/hep.26122

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-22249050, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-25290070, KAKENHI-PLANNED-22130005
  • [Journal Article] PathAct: a novel method for pathway analysis using gene expression profiles.2013

    • Author(s)
      Mogushi K, Tanaka H.
    • Journal Title

      Bioinformation

      Volume: 9 Pages: 394-400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25290070
  • [Presentation] Gene expression analysis and cancer signaling networks2017

    • Author(s)
      Kaoru Mogushi
    • Organizer
      International Symposium on BioComplexity
    • Place of Presentation
      B-Conプラザ (別府)
    • Year and Date
      2017-01-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26870175
  • [Presentation] 小細胞肺がんにおけるヒストン脱メチル化酵素LSD1+8aの役割2016

    • Author(s)
      Aditya Wirawan、田島健、丈達陽順、柳下薫寛、高遼、Moulid Hidayat、金丸良太、濃沼淑芳、井原宏彰、嶋田奈緒子、茂櫛薫、高橋史行、高橋和久
    • Organizer
      第57回日本肺癌学会総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2016-12-19
    • Data Source
      KAKENHI-PROJECT-16K09586
  • [Presentation] 舌癌同一患者における原発巣-転移リンパ節間の全ゲノムコピー数異常の比較2015

    • Author(s)
      森田琢磨、鵜澤成一、茂櫛薫、名生邦彦、高橋謙一郎、道川千絵子、炭野淳、出雲俊之、原田清
    • Organizer
      第53回日本癌治療学会学術集会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2015-10-15
    • Data Source
      KAKENHI-PROJECT-15K11288
  • [Presentation] A novel method for pathway analysis using gene expression profiles2013

    • Author(s)
      茂櫛薫、田中博
    • Organizer
      CBI学会2013年大会
    • Place of Presentation
      タワーホール船堀
    • Data Source
      KAKENHI-PROJECT-25290070
  • []

  • 1.  Hiromitsu Komiayama (30348982)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  加藤 俊介 (40312657)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 3.  Tajima Ken (50384102)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 4.  Takahashi Fumiyuki (70327823)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 5.  Takahashi Kazuhisa (80245711)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 6.  TSUBOTA Akihito (90322643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  Tanaka Hiroshi (60155158)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  Tanaka Shinji (30253420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 9.  Morioka Katuki (30351589)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TAKAHSHI Makoto (40445549)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  KAMIYAMA HIROHIKO (00365595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  UZAWA NARIKAZU (30345285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  Okuzawa Atsushi (00348913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  Yaginuma Yukihiro (60338415)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  坂本 啓 (00302886)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  島田 周 (20609705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  SATAKE Wataru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  Itoh Michiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  FUNAYAMA Manabu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  秋山 好光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  工藤 篤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  戸田 達史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  菅波 孝祥
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  深町 博史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  藤井 智明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  傳田 忠道
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  傅田 香里
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  落合 匠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  名生 邦彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  西岡 健弥
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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