YAMASHITA Nami 山下奈真

… Alternative Names

山下奈真ヤマシタナミ

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Researcher Number	60608967
Other IDs	https://orcid.org/0000-0001-7182-1090
Affiliation (Current)	2025: 公益財団法人がん研究会, 有明病院乳腺外科, 医長
Affiliation (based on the past Project Information) *help	2025: 公益財団法人がん研究会, 有明病院乳腺外科, 医長 2023: 公益財団法人がん研究会, 有明病院乳腺外科, 医長 2017 – 2021: 九州大学, 大学病院, 助教 2016: 九州大学, 医学研究院, 助教 2015: 九州大学, 医学(系)研究科(研究院), 助教 … More 2014: 九州大学, 大学病院, 助教 2014: 九州大学, 大学病院, 医員 2013 – 2014: 九州大学, 大学病院, その他 Less
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / General surgery Except Principal Investigator General surgery / Basic Section 53020:Cardiology-related / Digestive surgery
Keywords	Principal Investigator EMT / E-cadherin / vimentin / トリプルネガティブ乳癌 / 多様性 / ゲノム不安定性 / collective invasion / Vimentin / 浸潤・転移 / 腫瘍免疫 … More / 幹細胞性 / 免疫・栄養 / 免疫回避 / DNA傷害耐性 / インターフェロン経路 / 薬剤耐性 / 癌幹細胞性 / MUC1-C / トリプルネガテイブ乳癌 / BRCA1機能異常 / BRCA1プロモーターメチル化 / BRCA1 dysfunction / heterogeneity / cancer invasion / BRCAness / basal-like乳癌 / triple-negative乳癌 / Axl / 上皮間葉系移行 … More Except Principal Investigator 外科 / がん幹細胞 / 乳癌 / 循環器内科学 / ゲノム / ゲノム遺伝子 / コピー数多型 / 遺伝子多型 / 予測因子 / 一塩基多様性 / 挿入欠失配列 / ゲノム変異 / 心毒性 / トラスツズマブ / 創薬 / プロテオーム / Sphere / 化合物ライブラリー / 造血幹細胞 / 集学的治療 / Type IVcollagen / plasma fibronectin / 腹膜播種 / sphere / シグナル伝達 / トランスレーショナルリサーチ / 薬剤反応性 / 細胞・組織 / 癌 / 腫瘍浸潤リンパ球 / 術前化学療法 / 化学療法 / サブタイプ / 癌抑制遺伝子 / ER陽性乳癌 / APOBEC3B / 染色体不安定性 / 遺伝子変異 / DNA修復 Less

治療抵抗性トリプルネガティブ乳癌の癌幹細胞性の分子機序解明と新規治療への展開Principal Investigator
- Principal Investigator
  
  山下奈真
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
Elucidating of Molecular Mechanisms of Heterogeneity in Triple Negative Breast Cancer and Development of Novel TherapeuticsPrincipal Investigator
- Principal Investigator
  
  山下奈真
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
  Kyushu University
Genetic polymorphisms predict development of trastuzumab-induced cardiotoxicity
- Principal Investigator
  
  Kisho Ohtani
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyushu University
Impact of the cancer stemness and immune checkpoint system in breast cancer
- Principal Investigator
  
  Tokunaga Eriko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Hospital Organization, Kyushu Cancer Center
Elucidation of Molecular Mechanisms of Biological Heterogeneity and Its Clinical Application in Triple-Negative Breast Cancer.Principal Investigator
- Principal Investigator
  
  YAMASHITA Nami
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells
- Principal Investigator
  
  Maehara Yoshihiko
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukuoka Dental College
  Kyushu University
Gemonic alteration, molecular subtypes and drug sensitivity in breast cancer
- Principal Investigator
  
  Tokunaga Eriko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Hospital Organization, Kyushu Cancer Center
  Kyushu University
Elucidation of Molecular Mechanisms of Epithelial-Mesenchymal Transition and Its Clinical Application in Triple-Negative Breast Cancer.Principal Investigator
- Principal Investigator
  
  YAMASHITA Nami
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University

All 2024 2023 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] IDENTIFICATION OF MUC1-C AS A TARGET FOR SUPPRESSING PROGRESSION OF HEAD AND NECK SQUAMOUS CELL CARCINOMAS2024
- Author(s)
  Nakashoji Ayako、Haratake Naoki、Bhattacharya Atrayee、Mao Weipu、Xu Kangjie、Wang Keyi、Daimon Tatsuaki、Ozawa Hiroki、Shigeta Keisuke、Fushimi Atsushi、Yamashita Nami、Morimoto Yoshihiro、Shimokawa Mototsugu、Saito Shin、Egloff Ann Marie、Uppaluri Ravindra、Long Mark D、Kufe Donald
- Journal Title
  
  Cancer Research Communications
  
  Volume: -
- DOI
  10.1158/2767-9764.crc-24-0011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08576
[Journal Article] MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells2024
- Author(s)
  Daimon Tatsuaki、Bhattacharya Atrayee、Wang Keyi、Haratake Naoki、Nakashoji Ayako、Ozawa Hiroki、Morimoto Yoshihiro、Yamashita Nami、Kosaka Takeo、Oya Mototsugu、Kufe Donald W.
- Journal Title
  
  Cell Death Discovery
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41420-023-01772-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08576
[Journal Article] MUC1-C Is a Common Driver of Acquired Osimertinib Resistance in NSCLC2024
- Author(s)
  Haratake Naoki、Ozawa Hiroki、Morimoto Yoshihiro、Yamashita Nami、Daimon Tatsuaki、Bhattacharya Atrayee、Wang Keyi、Nakashoji Ayako、Isozaki Hideko、Shimokawa Mototsugu、Kikutake Chie、Suyama Mikita、Hashinokuchi Asato、Takada Kazuki、Takenaka Tomoyoshi、Yoshizumi Tomoharu、Mitsudomi Tetsuya、Hata Aaron N.、Kufe Donald
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 19 Issue: 3 Pages: 434-450
- DOI
  10.1016/j.jtho.2023.10.017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08576
[Journal Article] A novel system to provide information via online YouTube videos and an evaluation of current online information about hereditary breast cancer2023
- Author(s)
  Iesato Asumi、Fushimi Atsushi、Tahara Rie、Terada Mitsuo、Iwase Madoka、Kawamura Chihiro、Yamashita Nami
- Journal Title
  
  Breast Cancer
  
  Volume: 31 Issue: 1 Pages: 63-74
- DOI
  10.1007/s12282-023-01512-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08576
[Journal Article] MUC1-C intersects chronic inflammation with epigenetic reprogramming by regulating the set1a compass complex in cancer progression2023
- Author(s)
  Bhattacharya Atrayee、Fushimi Atsushi、Wang Keyi、Yamashita Nami、Morimoto Yoshihiro、Ishikawa Satoshi、Daimon Tatsuaki、Liu Tao、Liu Song、Long Mark D.、Kufe Donald
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1
- DOI
  10.1038/s42003-023-05395-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08576
[Journal Article] MUC1-C is necessary for SHP2 activation and BRAF inhibitor resistance in BRAF(V600E) mutant colorectal cancer2023
- Author(s)
  Morimoto Yoshihiro、Yamashita Nami、Hirose Haruka、Fushimi Atsushi、Haratake Naoki、Daimon Tatsuaki、Bhattacharya Atrayee、Ahmad Rehan、Suzuki Yozo、Takahashi Hidekazu、Kufe Donald W.
- Journal Title
  
  Cancer Letters
  
  Volume: 559 Pages: 216116-216116
- DOI
  10.1016/j.canlet.2023.216116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08576
[Journal Article] MUC1-C is a master regulator of MICA/B NKG2D ligand and exosome secretion in human cancer cells2023
- Author(s)
  Morimoto Yoshihiro、Yamashita Nami、Daimon Tatsuaki、Hirose Haruka、Yamano Shizuka、Haratake Naoki、Ishikawa Satoshi、Bhattacharya Atrayee、Fushimi Atsushi、Ahmad Rehan、Takahashi Hidekazu、Dashevsky Olga、Mitsiades Constantine、Kufe Donald
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 11 Issue: 2 Pages: e006238-e006238
- DOI
  10.1136/jitc-2022-006238
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08576
[Journal Article] MUC1-C integrates aerobic glycolysis with suppression of oxidative phosphorylation in triple-negative breast cancer stem cells2023
- Author(s)
  Yamashita Nami、Withers Henry、Morimoto Yoshihiro、Bhattacharya Atrayee、Haratake Naoki、Daimon Tatsuaki、Fushimi Atsushi、Nakashoji Ayako、Thorner Aaron R.、Isenhart Emily、Rosario Spencer、Long Mark D.、Kufe Donald
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 11 Pages: 108168-108168
- DOI
  10.1016/j.isci.2023.108168
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08576
[Journal Article] Factors associated with prolonged overall survival in patients with postmenopausal estrogen receptor-positive advanced breast cancer using real-world data: a follow-up analysis of the JBCRG-C06 Safari study.2019
- Author(s)
  Kawaguchi H, Masuda N, Nakayama T, Aogi K, Anan K, Ito Y, Ohtani S, Sato N, Saji S, Takano T, Tokunaga E, Nakamura S, Hasegawa Y, Hattori M, Fujisawa T, Morita S, Yamaguchi M, Yamashita H, Yamashita T, Yamamoto Y, Yotsumoto D, Toi M, Ohno S.
- Journal Title
  
  Breast Cancer
  
  Volume: 27 Issue: 3 Pages: 389-398
- DOI
  10.1007/s12282-019-01029-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10574
[Journal Article] Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer.2019
- Author(s)
  Modi S, Saura C, Yamashita T, Park YH, Kim SB, Tamura K, Andre F, Iwata H, Ito Y, Tsurutani J, Sohn J, Denduluri N, Perrin C, Aogi K, Tokunaga E, Im SA, Lee KS, Hurvitz SA, Cortes J, Lee C, Chen S, Zhang L, Shahidi J, Yver A, Krop I; DESTINY-Breast01 Investigators.
- Journal Title
  
  N Engl J Med
  
  Volume: 382 Issue: 7 Pages: 610-621
- DOI
  10.1056/nejmoa1914510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10574
[Journal Article] Epithelial Paradox: Clinical Significance of Coexpression of E-cadherin and Vimentin With?Regard to Invasion and Metastasis of Breast?Cancer2018
- Author(s)
  Yamashita Nami、Tokunaga Eriko、Iimori Makoto、Inoue Yuka、Tanaka Kimihiro、Kitao Hiroyuki、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko
- Journal Title
  
  Clinical Breast Cancer
  
  Volume: 印刷中 Issue: 5 Pages: e1003-e1009
- DOI
  10.1016/j.clbc.2018.02.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19899, KAKENHI-PROJECT-18K08576, KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-15H05792
[Journal Article] Differences in PD-L1 expression on tumor and immune cells between lung metastases and corresponding primary tumors.2018
- Author(s)
  Takamori S, Takada K, Tagawa T, Toyokawa G, Hirai F, Yamashita N, Okamoto T, Oki E, Yoshizumi T, Oda Y, Maehara Y.
- Journal Title
  
  Surg Oncol
  
  Volume: 27(4) Issue: 4 Pages: 637-641
- DOI
  10.1016/j.suronc.2018.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08576
[Journal Article] Y-box binding protein YBX1 and its correlated genes as biomarkers for poor outcomes in patients with breast cancer2018
- Author(s)
  Shibata Tomohiro、Tokunaga Eriko、Hattori Satoshi、Watari Kosuke、Murakami Yuichi、Yamashita Nami、Oki Eiji、Itou Junji、Toi Masakazu、Maehara Yoshihiko、Kuwano Michihiko、Ono Mayumi
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 98 Pages: 37216-37228
- DOI
  10.18632/oncotarget.26469
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15508, KAKENHI-PROJECT-15H05792
[Journal Article] The Local Recurrence of Breast Cancer with Squamous Metaplasia and Obvious Histological Heterogeneity.2017
- Author(s)
  Yamashita N, Tokunaga E, Yamamoto H, Shimizu C, Taketani K, Inoue Y, Saeki H, Oki E, Maehara Y.
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Pages: 5249-5254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10574
[Journal Article] Protein Expression of Programmed Death 1 Ligand 1 and HER2 in Gastric Carcinoma2017
- Author(s)
  Oki Eiji、Okano Shinji、Saeki Hiroshi、Umemoto Yuichiro、Teraishi Koji、Nakaji Yu、Ando Koji、Zaitsu Yoko、Yamashita Nami、Sugiyama Masahiko、Nakashima Yuichiro、Ohgaki Kippei、Oda Yoshinao、Maehara Yoshihiko
- Journal Title
  
  Oncology
  
  Volume: 93 Issue: 6 Pages: 387-394
- DOI
  10.1159/000479231
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10502, KAKENHI-PROJECT-15H05792, KAKENHI-PROJECT-16K15620, KAKENHI-PROJECT-16K19899
[Journal Article] The relationship between the expression of FOXA1 and GATA3 and the efficacy of neoadjuvant endocrine therapy.2017
- Author(s)
  Tanaka K, Tokunaga E, Yamashita N, Sagara Y, Ohi Y, Taguchi K, Ohno S, Okano S, Oda Y, Maehara Y.
- Journal Title
  
  Breast Cancer
  
  Volume: 24 Issue: 3 Pages: 384-392
- DOI
  10.1007/s12282-016-0714-3
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
[Journal Article] Clinical Significance of the Wild Type p53-Induced Phosphatase 1 Expression in Invasive Breast Cancer2017
- Author(s)
  Inoue Yuka、Yamashita Nami、Kitao Hiroyuki、Tanaka Kimihiro、Saeki Hiroshi、Oki Eiji、Oda Yoshinao、Tokunaga Eriko、Maehara Yoshihiko
- Journal Title
  
  Clinical Breast Cancer
  
  Volume: 印刷中 Issue: 4 Pages: e643-e650
- DOI
  10.1016/j.clbc.2017.11.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-16K19899, KAKENHI-PROJECT-18K08576, KAKENHI-PROJECT-15H05792
[Journal Article] Biological and clinical significance of loss of heterozygosity at the INPP4B gene locus in Japanese breast cancer.2016
- Author(s)
  Tokunaga E, Yamashita N, Kitao H, Tanaka K, Taketani K, Inoue Y, Saeki H, Oki E, Oda Y, Maehara Y.
- Journal Title
  
  The Breast
  
  Volume: 26 Pages: 62-68
- DOI
  10.1016/j.breast.2015.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
[Journal Article] The impact of the expression of vimentin and Axl in breast cancer.2016
- Author(s)
  Tanaka K, Tokunaga E, Inoue Y, Yamashita N, Saeki H, Okano S, Kitao H, P Oki E, Oda Y, Maehara Y.
- Journal Title
  
  Clin Breast Cancer
  
  Volume: 16 Issue: 6 Pages: 520-526
- DOI
  10.1016/j.clbc.2016.06.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
[Journal Article] Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women.2016
- Author(s)
  Tokunaga E, Yamashita N, Tanaka K, Inoue Y, Akiyoshi S, Saeki H, Oki E, Kitao H, Maehara Y.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 12 Pages: e0168090-e0168090
- DOI
  10.1371/journal.pone.0168090
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
[Journal Article] Prognostic impact of des-γ-carboxyl prothrombin in living-donor liver transplantation for recurrent hepatocellular carcinoma.2015
- Author(s)
  Harimoto N, Yoshida Y, Kurihara T, Takeishi K, Itoh S, Harada N, Tsujita E, Yamashita YI, Uchiyama H, Soejima Y, Ikegami T, Yoshizumi T, Kawanaka H, Ikeda T, Shirabe K, Saeki H, Oki E, Kimura Y, Maehara Y2.
- Journal Title
  
  Transplant Proc.
  
  Volume: 47(3) Issue: 3 Pages: 703-4
- DOI
  10.1016/j.transproceed.2014.09.178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05792
[Journal Article] Triple therapy using direct-acting agents for recurrent hepatitis C after liver transplantation: a single-center experience.2015
- Author(s)
  Ikegami T, Yoshizumi T, Soejima Y, Harimoto N, Itoh S, Takeishi K, Uchiyama H, Kawanaka H, Yamashita YI, Tsujita E, Harada N, Oki E, Saeki H, Kimura Y, Shirabe K, Maehara Y.
- Journal Title
  
  Transplant Proc.
  
  Volume: 47(3): Issue: 3 Pages: 730-2
- DOI
  10.1016/j.transproceed.2014.10.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05792
[Journal Article] Outcomes After Laparoscopic Hepatectomy in the Semi-prone Position for Hepatocellular Carcinoma Located in Segment 6, 7, or 8.2015
- Author(s)
  Harimoto N, Ikeda T, Takeishi K, Itoh S, Yamashita Y, Ikegami T, Yoshizumi T, Kawanaka H, Shirabe K, Maehara Y
- Journal Title
  
  Anticancer Res.
  
  Volume: 35(7) Pages: 4167-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05792
[Journal Article] Education and imaging. Hepatology: Rare Stevens-Johnson syndrome and vanishing bile duct syndrome induced by acetaminophen, requiring liver transplantation.2015
- Author(s)
  Harimoto N, Wang H, Ikegami T, Takeishi K, Itoh S, Yamashita YI, Yoshizumi T, Aishima S, Shirabe K, Oda Y, Maehara Y.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 30(4): Issue: 4 Pages: 656-656
- DOI
  10.1111/jgh.12849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05792
[Journal Article] Epigenetic Inactivation of BRCA1 Through Promoter Hypermethylation and Its Clinical Importance in Triple-Negative Breast Cancer.2015
- Author(s)
  Yamashita N, Tokunaga E, Kitao H, Hitchins M, Inoue Y, Tanaka K, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Oda Y, Saeki H, Oki E, Maehara Y.
- Journal Title
  
  Clin Breast Cancer
  
  Volume: 15 Issue: 6 Pages: 498-504
- DOI
  10.1016/j.clbc.2015.06.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461949
[Journal Article] Impact of GATA-3 and FOXA1 expression in patients with hormone receptor-positive/HER2-negative breast cancer.2014
- Author(s)
  Hisamatsu Y, Tokunaga E, Yamashita N, Akiyoshi S, Okada S, Nakashima Y, Taketani K, Aishima S, Oda Y, Morita M, Maehara Y.
- Journal Title
  
  Breast Cancer
  
  Volume: なし
- Data Source
  KAKENHI-PROJECT-26461949
[Journal Article] Overexpression of metadherin/MTDH is associated with an aggressive phenotype and a poor prognosis in invasive breast cancer.2014
- Author(s)
  Tokunaga E, Nakashima Y, Yamashita N, Hisamatsu Y, Okada S, Akiyoshi S, Aishima S, Kitao H, Morita M, Maehara Y.
- Journal Title
  
  Breast Cancer
  
  Volume: 21 Issue: 3 Pages: 341-349
- DOI
  10.1007/s12282-012-0398-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591896, KAKENHI-PROJECT-25861160
[Journal Article] Molecular mechanisms regulating the hormone sensitivity of breast cancer.2014
- Author(s)
  Tokunaga E1, Hisamatsu Y, Tanaka K, Yamashita N, Saeki H, Oki E, Kitao H, Maehara Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105(11) Issue: 11 Pages: 1377-1377
- DOI
  10.1111/cas.12521
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25861160, KAKENHI-PROJECT-26461949
[Journal Article] Vimentin as a poor prognostic factor for triple-negative breast cancer.2013
- Author(s)
  Yamashita N, Tokunaga E, Kitao H, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Aishima S, Morita M, Maehara Y.
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 139 Issue: 5 Pages: 739-746
- DOI
  10.1007/s00432-013-1376-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591896, KAKENHI-PROJECT-25861160
[Presentation] トリプルネガティブ乳癌の癌幹細胞性に焦点を当てた分子標的治療の探究2024
- Author(s)
  山下奈真, Henry Withers, 森本祥悠, 伏見淳, 原武直紀, Mark D. Long, Donald Kufe,上野貴之
- Organizer
  第124回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08576
[Presentation] MUC1-C INTEGRATES INDUCTION OF AEROBIC GLYCOLYSIS IN TRIPLE-NEGATIVE BREAST CANCER STEM CELLS2023
- Author(s)
  Nami Yamashita, Henry Withers, Yoshihiro Morimoto, Atsushi Fushimi, Naoki Haratake, Atrayee Bhattacharya, Tatsuaki Diamon, Ayako Nakashoji, Mark D. Long, Donald Kufe
- Organizer
  Japan Breast Cancer Symposium 2023
- Data Source
  KAKENHI-PROJECT-18K08576
[Presentation] MUC1-C INTEGRATES CHRONIC ACTIVATION OF INTERFERON PATHWAYS WITH CHROMATIN REMODELING IN TREATMENT RESISTANCE OF TRIPLE-NEGATIVE BREAST CANCER2023
- Author(s)
  Yamashita N, Morimoto Y, Fushimi A, Bhattacharya A, Inoue Y, Daimon T, Haratake N, Hu Q, Liu T, Withers H, Liu S, Shapiro GI, Yoshizumi T, Ueno T, S Ohno, Long MD, Kufe D.
- Organizer
  San Antonio Breast Cancer Symposium 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08576
[Presentation] 非浸潤性乳管癌における免疫微小環境について2019
- Author(s)
  秋吉清百合、山下奈真、佐野瑛貴、茂地智子、久松雄一、佐伯浩司、沖英次、森正樹
- Organizer
  第26回日本乳癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08576
[Presentation] The immune microenvironment of ductal carcinoma in situ of the breast.2019
- Author(s)
  Nami Yamashita, Eiki Sano, Yuichi Hisamatsu, Tomoko Shigechi, Eriko Tokunaga, Hiroshi Saeki, Eiji Oki, Masaki Mori
- Organizer
  第119回日本外科学会定期学術術集会
- Data Source
  KAKENHI-PROJECT-18K08576
[Presentation] 乳癌におけるPrognostic Nutritional Index (PNI)とControlling Nutritional Status(CONUT)の臨床的意義についての比較検討2018
- Author(s)
  山下奈真、井上有香、佐伯浩司、沖英次、徳永えり子、前原喜彦
- Organizer
  第118回日本外科学会定期学術術集会
- Data Source
  KAKENHI-PROJECT-18K08576
[Presentation] The immune microenvironment of ductal carcinoma in situ of the breast.2018
- Author(s)
  Nami Yamashita, Yuichi Hisamatsu, Tomoko Shigechi, Eriko Tokunaga, Hiroshi Saeki, Eiji Oki, Masaki Mori.
- Organizer
  San Antonio Breast Cancer Symposium 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08576
[Presentation] 乳癌における術前末梢血リンパ球数・単球数比の臨床的意義についての検討2018
- Author(s)
  山下奈真, 徳永えり子, 井上有香, 茂地智子, 佐伯浩司, 沖英次, 前原喜彦
- Organizer
  第26回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08576
[Presentation] The comparison of clinical impact of the Prognostic Nutritional Index (PNI) and Controlling Nutritional Status (CONUT) score on breast cancer patients’ survival.2017
- Author(s)
  Nami Yamashita, Yuka Inoue, Hiroshi Saeki, Eiji Oki, Eriko Tokunaga, Yoshihiko Maehara
- Organizer
  第54回日本癌治療学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19899
[Presentation] The clinical impact of the PD-L1 expression and immunonutritional status on breast cancer survival2017
- Author(s)
  Nami Yamashita, Eriko Tokunaga, Yuka Inoue, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19899
[Presentation] 術前化学療法を受けたHER2陽性乳癌におけるTIL及びPD-L1出現の意義2017
- Author(s)
  徳永えり子、田口健一、山下奈真、森田勝、石田真弓
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10574
[Presentation] Epithelial paradox; 乳癌細胞におけるE-cadherinとvimentinの共局在の意義2017
- Author(s)
  山下奈真, 徳永えり子, 井上有香, 田中仁寛, 佐伯浩司, 沖英次, 前原喜彦
- Organizer
  第25回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19899
[Presentation] The clinical impact of the Prognostic Nutritional Index (PNI) and Controlling Nutritional Status (CONUT) score on breast cancer patients survival.2017
- Author(s)
  Nami Yamashita, Yuka Inoue, Kimihiro Tanaka, Hiroshi Saeki, Eiji Oki, Eriko Tokunaga, Yoshihiko Maehara
- Organizer
  ASCO annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19899
[Presentation] Liver re-transplantation for graft failure: What are optimal selection criteria?2016
- Author(s)
  Ikegami T., Yoshizumi T., Uchiyama H.,Harimoto N., Itoh S., Okabe H., Harada N., Yamashita YI., Soejima Y., Mehara Y.
- Organizer
  第71回日本消化器外科学会
- Place of Presentation
  徳島
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] PURE LAPAROSCOPIC IN SEMIPRONE POSITION USING A DUAL HANDLING TECHNIQUE WITH A INTERCOSTAL PORT.2016
- Author(s)
  Ikeda T., Yamashita Y., Harimoto N., Takeishi K.,Ito S., Ikegami T., Yoshizumi T., Akahoshi T., Shirabe K., Maehara Y., Hashizume M.
- Organizer
  24th International congress of the EAES
- Place of Presentation
  Amsterdam
- Year and Date
  2016-06-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] Epithelial paradox; clinical significance of E-cadherin and vimentin expression pattern in invasive breast cancer.2016
- Author(s)
  Nami Yamashita, Eriko Tokunaga, Yuka Inoue, Kimihiro Tanaka, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara
- Organizer
  The 14th Asian Breast Diseases Association
- Place of Presentation
  Fukuoka
- Year and Date
  2016-09-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19899
[Presentation] Epithelial paradox; clinical significance of co-expression of E-cadherin and vimentin in the invasion and the metastasis of breast cancer.2016
- Author(s)
  Nami Yamashita, Eriko Tokunaga, Yuka Inoue, Kimihiro Tanaka, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara
- Organizer
  San Antonio Breast Cancer Symposium 2016
- Place of Presentation
  Texas
- Year and Date
  2016-12-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19899
[Presentation] Management and outcomes of portal vein thrombosis in living donor liver transplantation2016
- Author(s)
  Ikegami T., Yoshizumi T., Uchiyama H., Harimoto N., Itoh S., Okabe H., Kimura K., Yamashita YI., Soejima Y., Maehara Y.
- Organizer
  第28回日本肝胆膵学会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2016-06-02
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] Epithelial paradox; clinical significance E-cadherin and vimentin expression pattern in invasive breast cancer.2016
- Author(s)
  Nami Yamashita, Eriko Tokunaga, Yuka Inoue, Kimihiro Tanaka, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19899
[Presentation] Clinical impact of the expression of polymeraseθ in breast cancer2016
- Author(s)
  Eriko Tokunaga, Yuka Inoue, Nami Yamashita, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461949
[Presentation] 小開腹による安全・低侵襲な生体肝移植肝葉グラフト採取術2016
- Author(s)
  池上　　徹、吉住　朋晴、山下　洋市、播本　憲史、伊藤　心二、木村　光一、池田　哲夫、前原　喜彦
- Organizer
  第70回手術手技研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] Epithelial paradox; 浸潤性乳管癌における浸潤形態のheterogeneityについて2016
- Author(s)
  山下奈真、徳永えり子、井上有香、田中仁寛、上尾裕紀、前原喜彦
- Organizer
  第23回日本乳癌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K19899
[Presentation] Clinical impact of the expression of APOBEC3B in breast cancer2015
- Author(s)
  Eriko Tokunaga, Nami Yamashita, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26461949
[Presentation] 腹腔鏡下肝切除術の安全性向上と適応拡大への工夫2015
- Author(s)
  池田　哲夫、山下　洋市、播本　憲史、武石　一樹、伊藤　心二、池上　　徹、吉住　朋晴、赤星朋比古、調　　　　憲、前原　　喜彦
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  浜松
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] 生体肝移植成績向上に向けた術式の工夫と周術期管理2015
- Author(s)
  吉住　朋晴、調　　　憲、池上　　　　徹、伊藤　心二、播本　憲史、武石　一樹、木村　光一、松本　佳大、今井　大祐、別城　悠樹、栗原　　　健、吉田　佳弘、山下　洋市、内山　秀昭、川中　博文、前原　喜彦
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  浜松
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] Optimizing Outcomes in Living Donor Liver Transplantation2015
- Author(s)
  吉住　朋晴、調　　　憲、池上　　　徹、播本　憲史、伊藤　心二、武石　一樹、山下　洋市、木村　光一、松本　佳大、今井　大祐、別城　悠樹、王　　歓林、栗原　　健、吉田　佳弘、池田　哲夫、内山　秀昭、川中　博文、前原　喜彦
- Organizer
  第27回日本肝胆膵外科学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] Various Types of Donor Resection in Japan2015
- Author(s)
  Ikegami T, Shirabe K, Yoshizumi T, Soejima Y,Uchiyama H, Yamashita Y, Maehara Y
- Organizer
  The Liver Week 2015
- Place of Presentation
  Busan, Korea
- Year and Date
  2015-09-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] 高齢者肝細胞癌におけるサルコペニアの意義2015
- Author(s)
  播本　憲史、調　　　憲、武石　一樹、伊藤　心二、山下　洋市、池上　　徹、吉住　朋晴、川中　博文、池田　哲夫、前原　喜彦
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  浜松
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] 上腹部正中切開による各種生体肝移植グラフト採取の工夫2015
- Author(s)
  池上　　徹、調　　　　憲、山下　洋市、吉住　朋晴、播本　憲史、伊藤　心二、武石　一樹、川中　博文、前原　喜彦
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  浜松
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] 肝移植におけるサルコペニアの問題点2015
- Author(s)
  播本　憲史、調　　憲、武石　一樹、伊藤　心二、栗原　健、吉田　佳弘、今井　大祐、別城　悠樹、王　　歓林、木村　光一、中川原　英和、松本　佳大、山下　洋市、池上　徹、吉住　朋晴、川中　博文、池田　哲夫、前原　喜彦
- Organizer
  第23回日本消化器関連学会週間（JDDW）
- Place of Presentation
  東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] 腹腔鏡下切除におけるトラブルシューティング2015
- Author(s)
  池田　哲夫、山下　洋市、播本　憲史、武石　一樹、伊藤　心二、池上　　徹、吉住　朋晴、赤星朋比古、調　　　　憲、橋爪　　誠、前原　喜彦
- Organizer
  第27回日本肝胆膵外科学会・学術集会
- Place of Presentation
  東京
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] 肝切後にマイクロサージェリーの技法を導入するAutoirrigation BipolarとEndo Quick Suture有用性の検討2015
- Author(s)
  池田　哲夫、播本　憲史、山下　洋市、武石　一樹、伊藤　心二、赤星朋比古、池上　　徹、吉住　朋晴、調　　　　憲、橋爪　　　誠、前原　　喜彦
- Organizer
  第27回日本肝胆膵外科学会・学術集会
- Place of Presentation
  東京
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] 肝予備能不良症例に対する腹腔鏡下肝切除の適応と成績「肝硬変合併肝細胞癌に対する腹腔鏡下肝切除の意義」2015
- Author(s)
  播本　憲史、調　　　憲、武石　一樹、伊藤　心二、山下　洋市、池上　徹、吉住　朋晴、川中　博文、池田　哲夫、前原　喜彦
- Organizer
  第27回日本肝胆膵外科学会・学術集会
- Place of Presentation
  東京
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] トリプルネガティブ乳癌の多様性とその分子機序2013
- Author(s)
  山下奈真、徳永えり子、武谷憲二、安藤幸滋、木村和恵、佐伯浩司、沖　英次、
- Organizer
  第113回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25861160
[Presentation] トリプルネガティブ乳癌におけるvimentin発現の意義2013
- Author(s)
  山下奈真、徳永えり子、田中仁寛、武谷憲二、安藤幸滋、佐伯浩司、沖英次、森田勝、前原喜彦
- Organizer
  第22回日本がん転移学会学術集会・総会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-25861160
[Presentation] Vimentin as a poor prognostic factor for triple negative breast cancer.2013
- Author(s)
  Nami Yamashita, Eriko Tokunaga, Hiroyuki Kitao, Yuichi Hisamatsu, Kenji Taketani, Sayuri Akiyoshi, Satoko Okada, Shinichi Aishima, Masaru Morita, Yoshihiko Maehara
- Organizer
  ASCO annual meeting 2013
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-25861160
[Presentation] 術前薬物療法のトランスレーショナルリサーチ
- Author(s)
  徳永えり子、山下奈真、田中仁寛、森田　勝、前原喜彦
- Organizer
  第22回日本乳癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2014-07-10 – 2014-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-26461949
[Presentation] Clinical significance of co-expression of E-cadherin and vimentin in invasive breast cancer.
- Author(s)
  Nami Yamashita, Eriko Tokunaga, Yuka Inoue, Kimihiro Tanaka, Yuichirou Nakashima, Kouji Ando, Kippei Ohgaki, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara
- Organizer
  14 th St. Gallen International Breast Cancer Conference Primary Therapy of Early Breast Cancer
- Place of Presentation
  Vienna
- Year and Date
  2015-03-18 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25861160
[Presentation] 乳癌の予後変遷とサブタイプとの関連
- Author(s)
  徳永えり子, 山下奈真, 田中仁寛, 上尾裕紀, 安藤幸滋, 佐伯浩司, 沖英次, 森田勝, 前原喜彦
- Organizer
  第52回　日本癌治療学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2014-08-28 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-26461949
[Presentation] トリプルネガティブ乳癌におけるBRCA1機能不全の分子機序
- Author(s)
  山下奈真、徳永えり子、武谷憲二、田中仁寛、安藤幸滋、木村和恵、佐伯浩司、沖　英次、森田勝、楠本哲也、前原喜彦
- Organizer
  第21回日本乳癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2014-07-10 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-25861160
[Presentation] Significance of E-cadherin and vimentin expression in invasive breast cancer.
- Author(s)
  Nami Yamashita, Eriko Tokunaga,Yuka Inoue, Kimihiro Tanaka, Yuichiro Nakashima,Kouji Ando, Kippei Ohgaki, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25861160
[Presentation] The clinical importance of BRCA1 promoter methylation and LOH in breast cancer.
- Author(s)
  Nami Yamashita, Eriko Tokunaga, Kimihiro Tanaka, Hiroyuki Kitao, Kouji Ando, Shuhei Ito, Hiroshi Saeki, Eiji Oki, Masaru Morita, Yoshihiko Maehara
- Organizer
  第114回日本外科学会定期学術術集会
- Place of Presentation
  京都
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-25861160

1. Tokunaga Eriko (50325453)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
2. 岡野慎士 (10380429)

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37. 伊藤心二 (90382423)

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38. 田川哲三 (90419557)

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39. 庄司文裕 (90444851)

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40. 中西良太 (90771254)

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41. 工藤健介 (90801663)

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42. 堤亮介 (60846541)

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43. 橋本直隆 (30608964)

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44. 久保信英 (20811748)

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45. 諸富洋介 (60645365)

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46. 安田光宏 (90269043)

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47. 久保真 (60403961)

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48. 秋吉清百合 (50567360)

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49. 筒井裕之 (70264017)

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50. 井手友美 (90380625)

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51. 柴田智博

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YAMASHITA Nami 山下 奈真

山下 奈真 ヤマシタ ナミ

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治療抵抗性トリプルネガティブ乳癌の癌幹細胞性の分子機序解明と新規治療への展開Principal Investigator

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Elucidating of Molecular Mechanisms of Heterogeneity in Triple Negative Breast Cancer and Development of Novel TherapeuticsPrincipal Investigator

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Genetic polymorphisms predict development of trastuzumab-induced cardiotoxicity

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Impact of the cancer stemness and immune checkpoint system in breast cancer

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Elucidation of Molecular Mechanisms of Biological Heterogeneity and Its Clinical Application in Triple-Negative Breast Cancer.Principal Investigator

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Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells

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Gemonic alteration, molecular subtypes and drug sensitivity in breast cancer

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Elucidation of Molecular Mechanisms of Epithelial-Mesenchymal Transition and Its Clinical Application in Triple-Negative Breast Cancer.Principal Investigator

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[Journal Article] IDENTIFICATION OF MUC1-C AS A TARGET FOR SUPPRESSING PROGRESSION OF HEAD AND NECK SQUAMOUS CELL CARCINOMAS2024

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[Journal Article] MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells2024

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[Journal Article] MUC1-C Is a Common Driver of Acquired Osimertinib Resistance in NSCLC2024

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[Journal Article] A novel system to provide information via online YouTube videos and an evaluation of current online information about hereditary breast cancer2023

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[Journal Article] MUC1-C intersects chronic inflammation with epigenetic reprogramming by regulating the set1a compass complex in cancer progression2023

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[Journal Article] MUC1-C is necessary for SHP2 activation and BRAF inhibitor resistance in BRAF(V600E) mutant colorectal cancer2023

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YAMASHITA Nami 山下奈真

山下奈真ヤマシタナミ