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Outani Hidetatsu  王谷 英達

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… Alternative Names

Otani Hidetatsu  王谷 英達

王谷 英達  オウタニ ヒデタツ

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Researcher Number 60727965
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 講師
Affiliation (based on the past Project Information) *help 2025: 大阪大学, 大学院医学系研究科, 講師
2022 – 2023: 大阪大学, 大学院医学系研究科, 講師
2021: 大阪大学, 医学系研究科, 講師
2019 – 2021: 大阪大学, 医学系研究科, 助教
2017: 大阪大学, 医学系研究科, 特任助教(常勤) … More
2016: 大阪大学, 医学部附属病院, 医員
2015: 地方独立行政法人大阪府立病院機構大阪府立成人病センター, 整形外科, 医員
2014: 大阪大学, 医学部附属病院, その他 Less
Review Section/Research Field
Principal Investigator
Basic Section 56020:Orthopedics-related
Except Principal Investigator
Orthopaedic surgery / Basic Section 56030:Urology-related
Keywords
Principal Investigator
エピゲノム / 軟部肉腫 / 融合遺伝子 / 薬物療法
Except Principal Investigator
融合遺伝子 / 血液バイオマーカー / 転移性骨腫瘍 / GDPP / 大阪臨床研究ネットワーク / 癌種横断的 … More / バイオマーカー / 骨転移 / 骨軟部肉腫 / 整形外科 / ゲノム / 癌 / 骨軟部腫瘍 / がんゲノム / ゲノム解析 / 肉腫 / 抗腫瘍効果 / 創薬 / Xenograft model / Targeted therapy / Pre-clinical study / Fusion gene / Xenograht model / Targetd therapy / Synovial sarcoma / 新規治療開発 / 滑膜肉腫 Less
  • Research Projects

    (6 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (54 People)
  •  転座関連肉腫に対する融合遺伝子をターゲットとした新規治療方法の開発Principal Investigator

    • Principal Investigator
      王谷 英達
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      The University of Osaka
  •  融合遺伝子のエピゲノム制御メカニズムの解明と融合遺伝子制御療法の開発Principal Investigator

    • Principal Investigator
      王谷 英達
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Osaka University
  •  GDPP is a novel tumor-agnostic blood biomarker for the diagnosis and monitoring the bone metastasis

    • Principal Investigator
      Yamamichi Gaku
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  High-throughput screening of soft tissue sarcoma cell lines for new drug developmentPrincipal Investigator

    • Principal Investigator
      Otani Hidetatsu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Osaka University
  •  Identification of diagnostic biomarker and novel fusion genes of bone and soft tissue sarcoma

    • Principal Investigator
      Matsuda Koichi
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Functional analysis of synovial sarcoma specific fusion-gene and identification of new therapeutic targets

    • Principal Investigator
      Kenichiro Hamada
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Osaka University

All 2022 2021 2020 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Clinical outcomes of patients with epithelioid sarcomas: impact and management of nodal metastasis2018

    • Author(s)
      Outani H, Imura Y, Tanaka T, Takenaka S, Oshima K, Hamada K, Kakunaga S, Joyama S, Naka N, Kudawara I, Ueda T, Araki N, Yoshikawa H.
    • Journal Title

      Int J Clin Oncol

      Volume: 23 Pages: 181-188

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Journal Article] Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma.2017

    • Author(s)
      Yamada S, Imura Y, Nakai T, Nakai S, Yasuda N, Kaneko K, Outani H, Takenaka S, Hamada K, Myoui A, Araki N, Ueda T, Itoh K, Yoshikawa H, Naka N.
    • Journal Title

      BMC Cancer

      Volume: 17(1) Issue: 1 Pages: 334-334

    • DOI

      10.1186/s12885-017-3324-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05448, KAKENHI-PROJECT-26462264, KAKENHI-PROJECT-15K15560
  • [Journal Article] Role of zoledronic acid in oncolytic virotherapy: Promotion of antitumor effect and prevention of bone destruction2017

    • Author(s)
      Yamakawa Yasuaki、Tazawa Hiroshi、Hasei Joe、Osaki Shuhei、Omori Toshinori、Sugiu Kazuhisa、Komatsubara Tadashi、Uotani Kouji、Fujiwara Tomohiro、Yoshida Aki、Kunisada Toshiyuki、Urata Yasuo、Kagawa Shunsuke、Ozaki Toshifumi、Fujiwara Toshiyoshi
    • Journal Title

      Cancer Science

      Volume: 108 Issue: 9 Pages: 1870-1880

    • DOI

      10.1111/cas.13316

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10862, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-16H05416, KAKENHI-PROJECT-15K10446
  • [Journal Article] p53-independent p21 induction by MELK inhibition2017

    • Author(s)
      Matsuda Tatsuo、Kato Taigo、Kiyotani Kazuma、Tarhan Yunus Emre、Saloura Vassiliki、Chung Suyoun、Ueda Koji、Nakamura Yusuke、Park Jae-Hyun
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 35 Pages: 57938-57947

    • DOI

      10.18632/oncotarget.18488

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-26710007, KAKENHI-PROJECT-16H02676
  • [Journal Article] Clinical significance of circulating miR-25-3p as a novel diagnostic and prognostic biomarker in osteosarcoma2017

    • Author(s)
      Fujiwara T, Uotani K, Yoshida A, Morita T, Nezu Y, Kobayashi E, Yoshida A5, Uehara T1, Omori T1, Sugiu K1, Komatsubara T, Takeda K, Kunisada T, Kawamura M, Kawai A, Ochiya T, Ozaki T
    • Journal Title

      Oncotarget

      Volume: - Issue: 20 Pages: 33375-33392

    • DOI

      10.18632/oncotarget.16498

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10050, KAKENHI-PROJECT-16K20054, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-16H05449
  • [Journal Article] Circulating MicroRNA-92b-3p as a Novel Biomarker for Monitoring of Synovial Sarcoma2017

    • Author(s)
      Uotani Koji、Fujiwara Tomohiro、Yoshida Aki、Iwata Shintaro、Morita Takuya、Kiyono Masahiro、Yokoo Suguru、Kunisada Toshiyuki、Takeda Ken、Hasei Joe、Numoto Kunihiko、Nezu Yutaka、Yonemoto Tsukasa、Ishii Takeshi、Kawai Akira、Ochiya Takahiro、Ozaki Toshifumi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 14634-14634

    • DOI

      10.1038/s41598-017-12660-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-16H05449
  • [Journal Article] Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma2017

    • Author(s)
      Nakai Takaaki、Imura Yoshinori、Tamiya Hironari、Yamada Shutaro、Nakai Sho、Yasuda Naohiro、Kaneko Keiko、Outani Hidetatsu、Takenaka Satoshi、Hamada Kenichiro、Myoui Akira、Araki Nobuhito、Ueda Takafumi、Itoh Kazuyuki、Yoshikawa Hideki、Naka Norifumi
    • Journal Title

      Cancer Medicine

      Volume: 6 Issue: 9 Pages: 2121-2130

    • DOI

      10.1002/cam4.1130

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-16H05448, KAKENHI-PROJECT-26462264, KAKENHI-PROJECT-15K15560
  • [Journal Article] Clinical outcomes of patients with epithelioid sarcomas: impact and management of nodal metastasis2017

    • Author(s)
      Outani Hidetatsu、Imura Yoshinori、Tanaka Takaaki、Takenaka Satoshi、Oshima Kazuya、Hamada Kenichiro、Kakunaga Shigeki、Joyama Susumu、Naka Norifumi、Kudawara Ikuo、Ueda Takafumi、Araki Nobuhito、Yoshikawa Hideki
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 23 Issue: 1 Pages: 181-188

    • DOI

      10.1007/s10147-017-1179-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-16H05448
  • [Journal Article] Functional and therapeutic relevance of hepatocyte growth factor/c-MET signaling in synovial sarcoma.2016

    • Author(s)
      Imura Y, Nakai T, Yamada S, Outani H, Takenaka S, Hamada K, Araki N, Itoh K, Yoshikawa H, Naka N.
    • Journal Title

      Cancer Sci.

      Volume: 107 Issue: 12 Pages: 1867-1876

    • DOI

      10.1111/cas.13092

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05448, KAKENHI-PROJECT-26462264, KAKENHI-PROJECT-15K15560
  • [Journal Article] Trabectedin is a promising antitumor agent for synovial sarcoma2016

    • Author(s)
      Yasui H, Imura Y, Outani H, Hamada K, Nakai T, Yamada S, Takenaka S, Sasagawa S, Araki N, Itoh K, Myoui A, Yoshikawa H, Naka N
    • Journal Title

      J Chemother

      Volume: 28(5) Pages: 417-424

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] 淡明細胞肉腫におけるHDAC阻害薬の抗腫瘍効果の検討2022

    • Author(s)
      前裕和、王谷英達
    • Organizer
      日本サルコーマ治療研究学会
    • Data Source
      KAKENHI-PROJECT-19K18498
  • [Presentation] HDAC阻害薬による淡明細胞肉腫有効遺伝子EWS-ATF1の発現制御メカニズムの解明とその効果を増強する薬剤の発見2022

    • Author(s)
      前裕和、王谷英達
    • Organizer
      日本整形外科学会 骨軟部腫瘍学術集会
    • Data Source
      KAKENHI-PROJECT-22K09375
  • [Presentation] HDAC阻害薬による淡明細胞肉腫融合遺伝子EWS-ATF1の発現抑制メカニズムの解明とその効果を増強する薬剤の発見2022

    • Author(s)
      前裕和、王谷英達
    • Organizer
      日本整形外科学会 骨軟部腫瘍学術集会
    • Data Source
      KAKENHI-PROJECT-19K18498
  • [Presentation] HDAC阻害薬による 淡明細胞肉腫融合遺伝子EWS-ATF1の 発現制御メカニズムの解明2021

    • Author(s)
      前裕和、王谷英達
    • Organizer
      日本整形外科学会 基礎学術集会
    • Data Source
      KAKENHI-PROJECT-19K18498
  • [Presentation] ハイスループットスクリーニングを用いた淡明細胞肉腫に対する抗腫瘍薬の探索2020

    • Author(s)
      前裕和、王谷英達
    • Organizer
      日本整形外科学会 基礎学術集会
    • Data Source
      KAKENHI-PROJECT-19K18498
  • [Presentation] Ewing-like sarcoma細胞株樹立と新規癒合遺伝子の解析2018

    • Author(s)
      安田直弘 中井翔 王谷英達 竹中聡 濱田健一郎 中紀文 吉川秀樹
    • Organizer
      日本サルコーマ治療研究学会学術集会
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] 淡明細胞肉腫に対するEribulin mesilateの抗腫瘍効果2018

    • Author(s)
      中井翔 安田直弘 王谷英達 竹中聡 濱田健一郎 中紀文 吉川秀樹
    • Organizer
      日本サルコーマ治療研究学会学術集会
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] Clinical outcomes and management of nodal metastasis in the patients with epithelioid sarcoma.2017

    • Author(s)
      Outani, H., Yoshikawa, H., et al.
    • Organizer
      Annual Meeting of the Connective Tissue Oncology Society (CTOS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02676
  • [Presentation] 淡明細胞肉腫に対する eribulin mesilate の抗腫瘍効果2017

    • Author(s)
      中井翔 安田直弘 王谷英達 竹中聡 濱田健一郎 中紀文 吉川秀樹
    • Organizer
      日本整形外科学会骨軟部腫瘍学会
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] 初診時転移を有する軟部肉腫の治療成績2017

    • Author(s)
      王谷英達 中井翔 安田直弘 竹中聡 濱田健一郎 中紀文 吉川秀樹
    • Organizer
      日本整形外科学会骨軟部腫瘍学会
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] 神経線維腫症 1 型に発症した悪性末梢神経鞘腫瘍に対する治療成績2017

    • Author(s)
      濱田健一郎 中井翔 安田直弘 王谷英達 竹中聡 中紀文 吉川秀樹
    • Organizer
      日本整形外科学会骨軟部腫瘍学会
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] Anti-tumor effects of Eribulin mesilate on clear cell sarcoma cell lines2017

    • Author(s)
      中井翔 安田直弘 王谷英達 竹中聡 濱田健一郎 中紀文 吉川秀樹
    • Organizer
      CTOS2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] 淡明細胞肉腫に対する trabectedin(Yondelis; ET-743)の抗腫瘍効果2017

    • Author(s)
      中井隆彰 王谷英達 中井翔 安田直弘 竹中聡 濱田健一郎 中紀文 吉川秀樹
    • Organizer
      日本整形外科学会骨軟部腫瘍学会
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] Clinilar resultsof Osteosarcoma patients of lower extremity under 12 years-old2017

    • Author(s)
      濱田健一郎 中井翔 安田直弘 王谷英達 竹中聡 中紀文 吉川秀樹
    • Organizer
      SICOT2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] Clinical outcomes and management of nodal metastasis is the patients with epithelioid sarcoma2017

    • Author(s)
      王谷英達 中井翔 安田直弘 竹中聡 濱田健一郎 中紀文 吉川秀樹
    • Organizer
      CTOS2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] The Effect of SS18-SSX on TUmor growth and initiation of synovial sarcoma2016

    • Author(s)
      Hidetatsu Outani, Takaaki Tanaka, Yoshinori Imura, Kazuya Oshima, Nobuhito Araki, Takaaki Nakai, Kenichiro Hamada, Takafumi Ueda, Hideki Yoshikawa, Norifumi Naka
    • Organizer
      Connective Tissue Oncology Society 2016 Annual Meeting
    • Place of Presentation
      Lisbon Portugal
    • Year and Date
      2016-11-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462264
  • [Presentation] Anti tumor effects of Trabectedin on Clear cell sarcoma cell lines2016

    • Author(s)
      Takaaki Nakai, Yoshinori Imura, Shutaro Yamada, Sho Nakai, Hidetatsu Outani, Satoshi Takenaka, Kenichiro Hamada, Akira Myoui, Nobuhito Araki, Kazuyuki Itoh, Hideki Yoshikawa, Norifumi Naka
    • Organizer
      Connective Tissue Oncology Society 2016 Annual Meeting
    • Place of Presentation
      Lisbon Portugal
    • Year and Date
      2016-11-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462264
  • 1.  中 紀文 (90601964)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 2.  Kenichiro Hamada (50649043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 3.  Matsuda Koichi (90401257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  Yamamichi Gaku (40882262)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  中村 卓郎 (00180373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  中山 タラントロバート (00365298)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  綿貫 宗則 (90451575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  吉川 秀樹 (60191558)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 42.  岡本 健 (30414113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  五嶋 孝博 (20272544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  岩田 慎太郎 (90549685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 45.  田中 啓之 (00432542)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  植村 元秀 (40631015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  武田 理宏 (70506493)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  千々松 良太 (60803210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  KAWAMURA Machiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  名井 陽
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  伊村 慶紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 52.  国定 俊之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 53.  尾崎 敏文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 54.  藤原 智洋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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