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OHNO Ryuzo
大野 竜三
Connect your ORCID iD
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Researcher Number
70093002
Affiliation (Current)
2018 : 愛知県がんセンター(研究所), その他部局等, その他
Affiliation (based on the past Project Information)
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2000 : 愛知県がんセンター, 病院長
1997 – 1999 : 浜松医科大学, 教授
1993 – 1999 : 浜松医科大学, 医学部, 教授
1992 : 名古屋大学, 医学部・附属病院分院, 助教授
1989 – 1992 : 名古屋大学, 医学部, 助教授
1987 – 1988 : 名古屋大学, 医学部, 講師
1986 : Nagoya University School of Medicine, 医学部, 講師
Review Section/Research Field
Principal Investigator
Hematology
Except Principal Investigator
Hematology
/
老化(加齢)
/
Biological Sciences
Keywords
Principal Investigator
急性前骨髄球性白血病 / 分化誘導療法 / レチノイン酸 / Am-80 / MEG-01 / RAR遺伝子 / all-trans retinoic acid / 分子生物学 / PML / 急性白血病
…
More
/ PML遺伝子 / CD38 / CD34 / 多剤耐性遺伝子 / matched-pair analysis / thrombopoietin receptor / MDR1 / TPA / JALSG / 骨髄巨核芽球細胞株 / 骨髄巨核球 / 細胞内レチノイン酸結合蛋白 / IIIa / 急性リンパ性白血病 / Megakaryocyte / acute promyelocytic leukemia / 細胞培養株 / レチノイドアンタゴニスト / As_2O_3 / MDS / 化学療法 / erythropoietin receptor / Megakaryoblastic cell line / 薬剤耐性 / 白血病 / Oncogene / <beta> -thromboglobulin / 微量残存腫瘍 / がん遺伝子 / 形貭転換 / レチノイン酸受容体 / 単クローン抗体 / IBMTR / RARA / glycoprotein IIb / エリスロポイエチンレセプター / cytoplasmic retinoic acid binding protein / 分化誘導 / Gene transfection / メタアナリシス / bone marrow transplantation / ハノ-バ-大学 / apoptosis / 形質転換 / University of Munster / FAB classification / 治療戦略 / MRC / 分子マ-カ- / MEGー01 / ドイツ連邦共和国 / Glycophorin A / 免疫グロブリン遺伝子 / cーfos / chemotherapy / meta-analysis / 遺伝子導入 / phorbol esters;TPA,分化誘導 / mdr1 / 亜砒酸 / phorbol esters / 癌瘍1号-713 / acute leukemia / Hematopoietic stem cells / Federal Republic of Germany / ミュンスタ-大学 / メタアナリス / retinoid / Multidrug resistant gene / cーsis / トランスジェニック・マウス / cALL / glycophorin A / Differentiation induction / P-glycoprotin / β-thromboglobulin / 多剤耐性 / 骨髄異形成症候群 / Vitamin A / プロテインS / 共同研究 / 急性骨髄性白血病 / Glycophorin-A / アポトーシス / 造血幹細胞 / Cooperative study / Leukemia / レチノイド / ポリプレン酸 / C-myc / c-fos / レトロウイルスベクタ- / PML-RARαキメラ遺伝子 / 骨髄幹細胞 / Hannover Medical School / C-fos / ユビキチン・プロテアゾーム / Pー糖蛋白 / Phorbol esters / culture cell line / Glycoprotein IIb / 分化 / ヌードマウス / differentiation therapy / mdr / 急性前骨髄性白血病 / Chemotherapy / マッチドペアアナリシス / PSVLベクタ- / Phenotypic change / CDR3 / 分子誘導療法 / 骨髄移植療法 / Drug resistance / c-sis / cーmyc / ブファリン / Coagulation factor / Protein S / 凝固因子 / 白血病細胞株 / c-myc / Retroviral vector / Culture cell line / レチノイン酸レセプター / CFU
…
More
Except Principal Investigator
急性前骨髄球性白血病 / NB4 / 急性骨髄性白血病 / 薬剤耐性 / シスプラチン耐性 / 多剤耐性 / 加齢 / p-糖蛋白 / B細胞分化 / PCR / レチノイン酸 / Acute myeloid leukemia / myeloid differentiation / MDR1遺伝子 / Surrogateマーカー / 抗体療法 / 亜砒酸 / 耐性克服剤 / RI標識抗体結合物 / ヒト化抗体 / P糖蛋白 / ホメオボックス遺伝子 / チオレドキシン / GVHD予防 / 癌組織血管内皮細胞 / アポトーシス / 超可変部遺伝子 / 微少残存腫瘍(MRD) / サロゲイトマーカー / 分子標的 / 癌組織血管 / ホメオボックスB遺伝子 / ABCカッセトファミリー / mutation / 治療効果 / アンチセンス核酸 / CMA676 / P-glycoprotein / ATRA耐性 / 糖鎖抗原GM2,GD2 / キメラ抗体 / 全トランス型レチノイン酸 / 新規分子標的 / Acute Promyelocytic Leukemia / ADF / エトポシド耐性 / 5ーフルオロウラシル耐性 / 微量残存腫瘍 / 細胞分化 / ヒト化抗CD33抗体 / 免疫グロブリン重鎖(IgH)遺伝子 / 全トランス型レチノイン酸耐性 / Antisense nucleotide / 免疫グログリン / 抗体サブクラス / Homeobox Box gene / 耐性克服 / Pー糖蛋白質 / All-trans Retinoic Acid (ATRA)-Resistance / ミサイル療法 / DNAトポイソメラーゼ / 骨髄性白血病 / 制癌剤耐性 / 遺伝子マーカー / モノクローナル抗体 / 分化誘導療法 / CDR-III / タミバロテン / B細胞レパトアー / 急性リンパ性白血病 / 分子誘導療法 / 抗がん剤 / 急性骨髄性白血病細胞株
Less
Research Projects
(
22
results)
Co-Researchers
(
57
People)
Project Start Year(Newest)
Project Start Year(Oldest)
白血病における分子標的療法の至適臨床応用と併用による効果増強に関する研究
Principal Investigator
OHNISHI Kazunori
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Hamamatsu University School of Medicine
Study of Resistance Mechanisms of All-trans Retinoic Acid in Acute Promyelocytic Leukemia
Principal Investigator
TAKESHITA Akihiro
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
Hamamatsu University School of Medicine
分子標的治療の臨床応用へのアプローチ
Principal Investigator
上田 龍三
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Nagoya City University
がん細胞分化機構の分子生物学的解明と分化誘導療法の臨床応用に関する基礎的研究
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hamamatsu University School of Medicine
Collaborative study for the best treatment of acute leukemia.
Principal Investigator
Principal Investigator
OHNO Ryuzo
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for international Scientific Research
Research Field
Hematology
Research Institution
Hamamatsu University School of Medicine
がん細胞分化機構の分子生物学的解明と分化誘導療法の臨床応用に関する基礎的研究
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hamamatsu University School of Medicine
臨床応用可能な抗がん剤耐性マーカーの探索とその克服
Principal Investigator
桑野 信彦
Project Period (FY)
1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyushu University
Cytokine receptor expression and gene in myelodysplastic syndromes.
Principal Investigator
Principal Investigator
OHNO Ryuzo
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Hematology
Research Institution
Hamamatsu University School of Medicine
Homeobox B genes expression in human leukemia cell lines during myelomonocytic differentiation
Principal Investigator
OHNISHI Kazunori
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
Hamamatsu University School of Medicine
がん細胞分化機構の分子生物学的の解明と分化誘導療法の臨床応用に関する基礎的研究
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hamamatsu University School of Medicine
レチノイン酸による急性前骨髄球性白血病の分化誘導療法と分化機構の細胞生物学的解明
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hamamatsu University School of Medicine
加齢にともなうB細胞免疫グロブリン遺伝子レパトアーの変遷
Principal Investigator
直江 知樹
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
老化(加齢)
Research Institution
Nagoya University
Differentiation therapy of acute promylocytic leukemia.
Principal Investigator
Principal Investigator
OHNO Ryuzo, 大野 龍三
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Hamamatsu Univ.
新しい制がん剤耐性遺伝子群の解析と克服法の確立
Principal Investigator
桑野 信彦
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
大分医科大学
遺伝子マーカーを指標にした微量残存腫瘍の高感度検出と治療効果の新評価法
Principal Investigator
直江 知樹
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
レチノイン酸による白血病の分化誘導療法と分化機構の分子生物学的解明
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
免疫遺伝子超可変部をマ-カとした2ステップPCR法による微量残存腫瘍の検出
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
Investigation on a cooperative development of stratergy on curative treatment of leukemia with Federal Republic of Germany
Principal Investigator
Principal Investigator
OHNO Ryuzo, 大野 龍三
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Nagoya University
ヌードマウス可移植性多剤耐性ヒト腫瘍細胞株を用いた抗腫瘍薬剤耐性克服に関する研究
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
Transfection of Multidrug Resistant Gene into Human Hematopoietic Stem Cells and its Clinical Application in Bone Marrow Transplantation
Principal Investigator
Principal Investigator
OHNO Ryuzo
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Hematology
Research Institution
Nagoya University
Analysis of genes involved in proliferation and differentiation of megakaryopoiesis using a human megakaryoblastic leukemia cell line
Principal Investigator
Principal Investigator
OHNO Ryuzo
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Hematology
Research Institution
Nagoya University School of Medicine
Differentiation of a human megaryoblastic cell line (MEG-01) and its production of platelets and platelet-derived factors
Principal Investigator
Principal Investigator
OHNO Ryuzo
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Hematology
Research Institution
Nagoya University
# of Projects (Dsc)
# of Projects (Asc)
1.
NAOE Tomoki
(50217634)
# of Collaborated Projects :
11results
# of Collaborated Products :
0results
2.
TAKESHITA Akihiro
(00242769)
# of Collaborated Projects :
6results
# of Collaborated Products :
0results
3.
OHNISHI Kazunori
(80252170)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
4.
福谷 久
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
5.
久保 和明
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
6.
本間 良夫
(70142114)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
7.
武藤 泰敏
(20010069)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
8.
橋本 祐一
(90164798)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
9.
TANIMOTO Mitsune
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
10.
TOMONAGA Masao
(40100854)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
11.
SAITO Hidehiko
(20153819)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
12.
OGURA Michinori
(40231229)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
13.
MORISHIMA Yasuo
(20220056)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
14.
桑野 信彦
(80037431)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
15.
石田 良司
(50150214)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
16.
垣塚 彰
(80204329)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
17.
TOBITA Tadasu
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
18.
REES John K
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
19.
FUJIMOTO Takeo
(10037442)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
20.
鬼頭 純三
(60022802)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
21.
黒沢 良和
(10109259)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
22.
西條 長宏
(00215526)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
23.
前原 喜彦
(80165662)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
24.
稲葉 実
(60085636)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
25.
加藤 芳郎
(20152754)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
26.
富田 章弘
(40251483)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
27.
谷川原 祐介
(30179832)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
28.
秋山 伸一
(60117413)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
29.
梅沢 一夫
(70114402)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
30.
上田 龍三
(20142169)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
31.
真弓 忠範
(00098485)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
32.
遠藤 啓吾
(10115800)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
33.
山口 俊晴
(90111327)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
34.
吉田 均
(30303548)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
35.
王 伯銘
(60223707)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
36.
栗山 一孝
(90128174)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
37.
RIEHM Hansjog
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
38.
BUCHNER Thomas
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
39.
SHOU Dong
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
40.
CHEN Sai-juan
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
41.
CHEN Zhu
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
42.
WANG Zen-yi
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
43.
YANAGI Mitsuaki
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
44.
DEGOS Laurent
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
45.
BURNETT Alan
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
46.
HOROWITZ Mary
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
47.
竹尾 高明
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
48.
伊藤 良則
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
49.
花井 陳雄
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
50.
森下 剛久
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
51.
RIEM Hansjog
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
52.
BUCHUER Thom
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
53.
CHUO Dong
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
54.
TAKESHITA Kaori
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
55.
新庄 香
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
56.
奥村 雅男
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
57.
OKUMURA Masao
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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