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OHNO Ryuzo
大野 竜三
Connect your ORCID iD
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Researcher Number
70093002
Affiliation (Current)
2021: 愛知県がんセンター(研究所), その他部局等, その他
Affiliation (based on the past Project Information)
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2000: 愛知県がんセンター, 病院長
1997 – 1999: 浜松医科大学, 教授
1993 – 1999: 浜松医科大学, 医学部, 教授
1992: 名古屋大学, 医学部・附属病院分院, 助教授
1989 – 1992: 名古屋大学, 医学部, 助教授
1987 – 1988: 名古屋大学, 医学部, 講師
1986: Nagoya University School of Medicine, 医学部, 講師
Review Section/Research Field
Principal Investigator
Hematology
Except Principal Investigator
Hematology
/
老化(加齢)
/
Biological Sciences
Keywords
Principal Investigator
レチノイン酸 / 分化誘導療法 / 急性前骨髄球性白血病 / Am-80 / MEG-01 / RAR遺伝子 / PML遺伝子 / 分子生物学 / 急性白血病 / all-trans retinoic acid
…
More
/ PML / 薬剤耐性 / 多剤耐性遺伝子 / 急性リンパ性白血病 / 白血病 / 細胞内レチノイン酸結合蛋白 / レチノイドアンタゴニスト / MDR1 / 化学療法 / As_2O_3 / acute promyelocytic leukemia / MDS / erythropoietin receptor / thrombopoietin receptor / CD34 / CD38 / IIIa / JALSG / matched-pair analysis / 骨髄巨核芽球細胞株 / 骨髄巨核球 / 細胞培養株 / Megakaryoblastic cell line / Megakaryocyte / TPA / 多剤耐性 / mdr1 / 白血病細胞株 / ヌードマウス / cALL / 免疫グロブリン遺伝子 / 微量残存腫瘍 / CDR3 / 分子マ-カ- / レチノイン酸受容体 / 急性前骨髄性白血病 / 分子誘導療法 / レチノイド / レチノイン酸レセプター / ポリプレン酸 / ブファリン / ユビキチン・プロテアゾーム / トランスジェニック・マウス / RARA / 亜砒酸 / 遺伝子導入 / Pー糖蛋白 / 造血幹細胞 / レトロウイルスベクタ- / 形貭転換 / 形質転換 / mdr / 骨髄幹細胞 / CFU / PSVLベクタ- / Gene transfection / Multidrug resistant gene / P-glycoprotin / Hematopoietic stem cells / Retroviral vector / Drug resistance / Phenotypic change / ドイツ連邦共和国 / 共同研究 / ミュンスタ-大学 / ハノ-バ-大学 / 治療戦略 / Federal Republic of Germany / Leukemia / Cooperative study / University of Munster / Hannover Medical School / Chemotherapy / FAB classification / PML-RARαキメラ遺伝子 / 癌瘍1号-713 / アポトーシス / Vitamin A / apoptosis / retinoid / cytoplasmic retinoic acid binding protein / 骨髄異形成症候群 / Glycophorin A / Glycoprotein IIb / エリスロポイエチンレセプター / Glycophorin-A / glycophorin A / glycoprotein IIb / 骨髄移植療法 / マッチドペアアナリシス / メタアナリシス / 急性骨髄性白血病 / メタアナリス / IBMTR / MRC / acute leukemia / chemotherapy / bone marrow transplantation / differentiation therapy / meta-analysis / 凝固因子 / プロテインS / β-thromboglobulin / 単クローン抗体 / culture cell line / Coagulation factor / Protein S / <beta> -thromboglobulin / MEGー01 / がん遺伝子 / 分化 / phorbol esters / 分化誘導 / cーmyc / cーfos / cーsis / phorbol esters;TPA,分化誘導 / c-myc / c-fos / c-sis / Culture cell line / Oncogene / Differentiation induction / Phorbol esters / C-myc / C-fos
…
More
Except Principal Investigator
急性前骨髄球性白血病 / 多剤耐性 / シスプラチン耐性 / 薬剤耐性 / 急性骨髄性白血病 / NB4 / 制癌剤耐性 / エトポシド耐性 / 5ーフルオロウラシル耐性 / Pー糖蛋白質 / MDR1遺伝子 / 耐性克服剤 / 微量残存腫瘍 / 遺伝子マーカー / 免疫グログリン / 超可変部遺伝子 / 急性リンパ性白血病 / PCR / 治療効果 / 免疫グロブリン重鎖(IgH)遺伝子 / 加齢 / B細胞レパトアー / CDR-III / B細胞分化 / 抗体サブクラス / mutation / 抗がん剤 / p-糖蛋白 / ABCカッセトファミリー / DNAトポイソメラーゼ / 耐性克服 / アポトーシス / 分子標的 / 抗体療法 / 分子誘導療法 / 癌組織血管 / 糖鎖抗原GM2,GD2 / ヒト化抗体 / チオレドキシン / サロゲイトマーカー / RI標識抗体結合物 / GVHD予防 / 分化誘導療法 / 新規分子標的 / Surrogateマーカー / 癌組織血管内皮細胞 / モノクローナル抗体 / ミサイル療法 / キメラ抗体 / 微少残存腫瘍(MRD) / ADF / CMA676 / タミバロテン / 亜砒酸 / ATRA耐性 / ヒト化抗CD33抗体 / ホメオボックスB遺伝子 / 細胞分化 / レチノイン酸 / アンチセンス核酸 / 急性骨髄性白血病細胞株 / ホメオボックス遺伝子 / 骨髄性白血病 / Homeobox Box gene / Acute myeloid leukemia / myeloid differentiation / Antisense nucleotide / 全トランス型レチノイン酸耐性 / P糖蛋白 / 全トランス型レチノイン酸 / Acute Promyelocytic Leukemia / All-trans Retinoic Acid (ATRA)-Resistance / P-glycoprotein
Less
Research Projects
(
22
results)
Co-Researchers
(
57
People)
Project Start Year (Newest)
Project Start Year (Oldest)
白血病における分子標的療法の至適臨床応用と併用による効果増強に関する研究
Principal Investigator
OHNISHI Kazunori
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Hamamatsu University School of Medicine
Study of Resistance Mechanisms of All-trans Retinoic Acid in Acute Promyelocytic Leukemia
Principal Investigator
TAKESHITA Akihiro
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
Hamamatsu University School of Medicine
分子標的治療の臨床応用へのアプローチ
Principal Investigator
上田 龍三
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Nagoya City University
がん細胞分化機構の分子生物学的解明と分化誘導療法の臨床応用に関する基礎的研究
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hamamatsu University School of Medicine
Collaborative study for the best treatment of acute leukemia.
Principal Investigator
Principal Investigator
OHNO Ryuzo
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for international Scientific Research
Research Field
Hematology
Research Institution
Hamamatsu University School of Medicine
がん細胞分化機構の分子生物学的解明と分化誘導療法の臨床応用に関する基礎的研究
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hamamatsu University School of Medicine
臨床応用可能な抗がん剤耐性マーカーの探索とその克服
Principal Investigator
桑野 信彦
Project Period (FY)
1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyushu University
Cytokine receptor expression and gene in myelodysplastic syndromes.
Principal Investigator
Principal Investigator
OHNO Ryuzo
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Hematology
Research Institution
Hamamatsu University School of Medicine
Homeobox B genes expression in human leukemia cell lines during myelomonocytic differentiation
Principal Investigator
OHNISHI Kazunori
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
Hamamatsu University School of Medicine
がん細胞分化機構の分子生物学的の解明と分化誘導療法の臨床応用に関する基礎的研究
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hamamatsu University School of Medicine
レチノイン酸による急性前骨髄球性白血病の分化誘導療法と分化機構の細胞生物学的解明
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hamamatsu University School of Medicine
加齢にともなうB細胞免疫グロブリン遺伝子レパトアーの変遷
Principal Investigator
直江 知樹
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
老化(加齢)
Research Institution
Nagoya University
Differentiation therapy of acute promylocytic leukemia.
Principal Investigator
Principal Investigator
OHNO Ryuzo, 大野 龍三
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Hamamatsu Univ.
新しい制がん剤耐性遺伝子群の解析と克服法の確立
Principal Investigator
桑野 信彦
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
大分医科大学
遺伝子マーカーを指標にした微量残存腫瘍の高感度検出と治療効果の新評価法
Principal Investigator
直江 知樹
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
レチノイン酸による白血病の分化誘導療法と分化機構の分子生物学的解明
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
免疫遺伝子超可変部をマ-カとした2ステップPCR法による微量残存腫瘍の検出
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
Investigation on a cooperative development of stratergy on curative treatment of leukemia with Federal Republic of Germany
Principal Investigator
Principal Investigator
OHNO Ryuzo, 大野 龍三
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Nagoya University
ヌードマウス可移植性多剤耐性ヒト腫瘍細胞株を用いた抗腫瘍薬剤耐性克服に関する研究
Principal Investigator
Principal Investigator
大野 竜三
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
Transfection of Multidrug Resistant Gene into Human Hematopoietic Stem Cells and its Clinical Application in Bone Marrow Transplantation
Principal Investigator
Principal Investigator
OHNO Ryuzo
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Hematology
Research Institution
Nagoya University
Analysis of genes involved in proliferation and differentiation of megakaryopoiesis using a human megakaryoblastic leukemia cell line
Principal Investigator
Principal Investigator
OHNO Ryuzo
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Hematology
Research Institution
Nagoya University School of Medicine
Differentiation of a human megaryoblastic cell line (MEG-01) and its production of platelets and platelet-derived factors
Principal Investigator
Principal Investigator
OHNO Ryuzo
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Hematology
Research Institution
Nagoya University
# of Projects (Dsc)
# of Projects (Asc)
1.
NAOE Tomoki
(50217634)
# of Collaborated Projects:
11 results
# of Collaborated Products:
0 results
2.
TAKESHITA Akihiro
(00242769)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
3.
OHNISHI Kazunori
(80252170)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
4.
福谷 久
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
5.
久保 和明
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
6.
本間 良夫
(70142114)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
武藤 泰敏
(20010069)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
橋本 祐一
(90164798)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
9.
TANIMOTO Mitsune
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
10.
TOMONAGA Masao
(40100854)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
SAITO Hidehiko
(20153819)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
OGURA Michinori
(40231229)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
13.
MORISHIMA Yasuo
(20220056)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
桑野 信彦
(80037431)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
15.
石田 良司
(50150214)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
垣塚 彰
(80204329)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
TOBITA Tadasu
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
18.
REES John K
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
19.
FUJIMOTO Takeo
(10037442)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
鬼頭 純三
(60022802)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
黒沢 良和
(10109259)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
西條 長宏
(00215526)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
前原 喜彦
(80165662)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
稲葉 実
(60085636)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
加藤 芳郎
(20152754)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
富田 章弘
(40251483)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
谷川原 祐介
(30179832)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
秋山 伸一
(60117413)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
梅沢 一夫
(70114402)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
上田 龍三
(20142169)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
真弓 忠範
(00098485)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
遠藤 啓吾
(10115800)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
山口 俊晴
(90111327)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
吉田 均
(30303548)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
王 伯銘
(60223707)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
栗山 一孝
(90128174)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
RIEHM Hansjog
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
BUCHNER Thomas
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
SHOU Dong
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
CHEN Sai-juan
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
41.
CHEN Zhu
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
42.
WANG Zen-yi
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
43.
YANAGI Mitsuaki
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
44.
DEGOS Laurent
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
45.
BURNETT Alan
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
46.
HOROWITZ Mary
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
47.
竹尾 高明
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
48.
伊藤 良則
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
49.
花井 陳雄
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
50.
森下 剛久
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
51.
RIEM Hansjog
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
52.
BUCHUER Thom
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
53.
CHUO Dong
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
54.
TAKESHITA Kaori
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
55.
新庄 香
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
56.
奥村 雅男
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
57.
OKUMURA Masao
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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