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SASAKAWA Chihiro  笹川 千尋

ORCIDConnect your ORCID iD *help
Researcher Number 70114494
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2017: 東京大学, 名誉教授
2012 – 2015: 東京大学, 医科学研究所, 名誉教授
1995 – 2011: Institute of Medical Science, University of Tokyo, Professor, 医科学研究所, 教授
2008: 東大, 医科学研究所, 教授
1994: 東京大学医科学研究所, 細菌研究部, 助教授 … More
1986 – 1994: 東京大学, 医科学研究所, 助教授
1992: 東大医科研, 助教授
1990: 東京大学医科学研究所, 助教授
1986: Institute of Medical Science, University of Tokyo, Associate Professor, 医科学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
細菌学 / Bacteriology (including Mycology) / Biological Sciences / Bacteriology (including Mycology) / Biological Sciences
Except Principal Investigator
Bacteriology (including Mycology) / 細菌学 / Biological Sciences / Biological Sciences / Pathological medical chemistry / Virology / Laboratory animal science
Keywords
Principal Investigator
赤痢菌 / 病原性 / 細胞侵入 / エフェクター / 感染 / Shigella / 自然免疫 / プラスミド / CagA / invasiveness … More / Pathogenicity / 下痢 / ビルレンス / 細菌病原性 / オートファジー / 病原細菌 / 上皮細胞 / 腸管 / 細菌感染 / III型分泌装置 / III型分泌機構 / gene regulation / invasion / intercellular spread / Virulence / 遺伝子解析 / ビルレンス遺伝子 / LPS / 染色体 / 遺伝子調節 / 細胞間拡散 / plasmid / transposon / 薬剤耐性 / トランスポゾン / Secretion system / Stomach / Helicobacter pylori / 分泌装置 / 胃 / ヘリコバクターピロリ / Type III secretion system / Autophagv / Inflamation / Effector / Innate Immunity / Infection / オートプァジー / 粘膜感染 / RhoGTPase / 細菌 / 細胞骨格タンパク質 / 感染症 / 赤痢因子 / 炎症 / pathogenicity / integrin / infection / Shigellosis / 細胞外マトリックス / インテグリン / 赤痢 / REGULATION / INVASION / PATHOGENICITY / SHIGELLA / VirB / 温度調節 / 遺伝子発現 / 低分子化合物 / 粘膜上皮 / バリアー / 抗菌剤 / 自然免疫回避 / インフラマソーム / 感染モデル / 組換えDNA / ISI / IS / 病原性大腸菌 / 遺伝子発現調節 / マイクロRNA / バイオインフォマティクス / HIF-1α / 細胞増殖 / miRNA / 感染防御機構 / ユビキチン / 細胞死 / 粘膜 / 病原因子 / III型分子機構 / 3型分泌装置 / 腸炎ビブリオ / チュブリン / タイプIII分泌系 … More
Except Principal Investigator
赤痢菌 / 病原性 / 細菌 / ビルレンス / 分子遺伝学 / 組換えDNA実験 / 病原細菌 / 緑膿菌 / 微生物 / 寄生虫 / ウイルス / 病原因子 / PCR / Plasmid / Pathogenicity / 遺伝子解析 / プラスミド / Ipa protein / Virulence / 細胞侵入性 / 病原細菌学 / コレラ菌 / virulence / Shigella / 細胞侵入 / 下痢 / ビルレンス遺伝子 / 免疫学 / 免疫 / 感染症 / 毒素 / 遺伝子 / 溶血毒 / 感染 / ビルレンス因子 / 電子線クライオトモグラフフィー / 3Dプリンター / 蛋白質 / ナノバイオ / 分子モーター / 電子顕微鏡 / 電子線クライオトモグラフィー / 3Dプリンター / 高速AFM / 質量分析 / ビデオライブラリー / スマートフォンアプリ / 技術開発・支援 / 急速凍結レプリカ法 / クライオ電子顕微鏡 / Pathogenic Bacteria / Gene Analysis / Molecular Genetics / Recombinant DNA Technology / Virulence gene / Pathogenic Bacteriology / 嫌気性菌 / ブローブ / ビブリオ / チフス菌 / サルモネラ / 分子進化 / 遺伝的制御機構 / ピルレンス / クローン化 / 塩基配列 / 病原菌 / 分子遺伝学的研究 / Molecular genetics / Recombinant DNA technology / Cell invasion / tolic Shigella / ビルレンズ / 組換之DNA実験 / 転写アクチベータ / caspase / macrophage / Cell differentiation / Cell death / Apoptosis / Bacterial infection / 病原性因子 / 単球 / U937 / 食細胞 / 細胞感染 / アポトーシス / マクロファージ / 細胞死 / 細胞分化 / カスパーゼ / スポトーシス / タンパク質分解 / PHICTX phage / virulence plasmid / Vibrio genome / hemolysin / motility / collagenase / Two component regulatory system / ヘリコバクター・ピロリ / ボツリヌス毒素 / B.fragilis / 腸炎ビブリオ / P.gingivalis / 赤痢菌Ipa蛋白 / φCTXファージ / ビルレンスプラスミド / ビブリオゲノム / Ipaタンパク / 運動性 / コラゲナーゼ / 2成分制御系 / detection / flagella / NaCl / Listeri monocytogenes / 食品 / 鞭毛 / 低温増殖能 / リステリア菌 / 診断 / 食塩 / べん毛 / リステリア / molecular genetics / vaccine / cell invasion / recombinant DNA experiments / pathogenicity / Shigella flexneri / 免疫病理学 / 分子遺伝学的解析 / サル実験 / 赤痢 / 組換えDNA / ワクチン / Vibrio cholerae / Pseudomonas aeruginosa / Shigella fiexneri / Pathogenic plasmid / Activation of toxin / Regulation of expression / Toxin gene / Bacterial pathogenesis / 溶原ファ-ジ / DNA塩基配例 / 調節遣伝子 / 病原性の調節 / 病原性ファージ / 病原性プラスミド / DNA塩基配列 / 調節遺伝子 / 病原遺伝子 / 病原プラスミド / 毒素の活性化 / 転写調節 / 毒素遺伝子 / 細菌性病原因子 / dysentery / chromosome map / chromosome / virulence gene / トランスポソン / NotI切断地図 / 細胞性赤痢 / 遺伝子調節 / 細胞間拡散 / 染色体地図 / 染色体 / 研究マトリックス / 宿主応答機構 / 病原性発現機構 / 増殖機構 / 感染現象 / スーパー抗原 / 内毒素 / 外毒素 / 細菌感染 / 細菌毒素 / 生体内輸送 / 侵入 / 定着 / 防禦反班 / 細胞内情報伝達定着 / 細菌感染症 / 連鎖球菌感染症 / 組織型フィブロネクチン / フィブロネクチン結合蛋白 / 化膿連鎖球菌 / 豚丹毒 / 抗菌薬 / 制御 / 標的細胞 / 胞内細菌 / RCR / プライマー / 実験動物 / 腸内細菌 / 発現調節 Less
  • Research Projects

    (33 results)
  • Research Products

    (167 results)
  • Co-Researchers

    (77 People)
  •  Generalization of harmonized supramolecular motility machinery and its diversity

    • Principal Investigator
      MIYATA Makoto
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka City University
  •  Study of bacterial stratagem to circumvent host innate immune system and its application.Principal Investigator

    • Principal Investigator
      SASAKAWA CHIHIRO
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Study of Shigella infectious strategy for the intestinal barrierPrincipal Investigator

    • Principal Investigator
      SASAKAWA Chihiro
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  赤痢菌の腸粘膜バリアー感染戦略の解明Principal Investigator

    • Principal Investigator
      笹川 千尋
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  赤痢菌感染におけるmicroRNAの役割の解明Principal Investigator

    • Principal Investigator
      笹川 千尋
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  Studies of proliferation and pathogenesis of extracellular gram-negative bacterial pathogensPrincipal Investigator

    • Principal Investigator
      SASAKAWA Chihiro
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Matrix of Infection Phenomena

    • Principal Investigator
      NOMOTO Akio
    • Project Period (FY)
      2006 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Microbial Chemistry Research Foundation
      The University of Tokyo
  •  Support for Research Techniques and Materials

    • Principal Investigator
      NOMOTO Akio
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
      Microbial Chemistry Research Foundation
  •  感染現象の研究マトリックスを構築するための企画調査研究

    • Principal Investigator
      NOMOTO Akio
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      The University of Tokyo
  •  The studies of Helicobacter pylori on the functions of effector protein and the mechanisms of gastric mucosa infection.Principal Investigator

    • Principal Investigator
      SASAKAWA Chihiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  Investigation of molecular interplay between Shigella effectors and the host factorsPrincipal Investigator

    • Principal Investigator
      SASAKA Chihiro
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  赤痢菌の粘膜上皮感染を決定するエフェクター蛋白質と微小管の相互作用の解明Principal Investigator

    • Principal Investigator
      笹川 千尋
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Induction of Cell Death upon Infection with Shigella flexneri

    • Principal Investigator
      IMAJOH-OHMI Shinobu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokyo
  •  細菌感染症発症機構の分子生物学的手法による解析とその治療への応用

    • Principal Investigator
      OGUMA Keiji
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Okayama University
  •  病原細菌由来ビルレンス因子と宿主細胞の相互連関との解析

    • Principal Investigator
      中村 信一
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kanazawa University
  •  Molecular mechanisms for shigellae invasion of and spreading among colonic epithelial cells.Principal Investigator

    • Principal Investigator
      SASAKAWA Chihiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  細菌由来病原因子による標的細胞機能変換作用の解析

    • Principal Investigator
      本田 武司
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Osaka University
  •  豚丹毒菌のヘモリジン遺伝子に関する遺伝学的および生物学的研究

    • Principal Investigator
      MAKINO Sou-ichi
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Obihiro University of Agriculture and Veterinary Medicine
  •  化膿連鎖球菌のF蛋白とヒト組織型フィブロネクチンにおける相互作用の解析

    • Principal Investigator
      OKADA Nobuhiko
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  Studies on molecular genetics of bacterial pathogenesis

    • Principal Investigator
      NAKAZAWA Teruko
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Yamaguchi University
  •  迅速核酸分析法を用いた実験動物腸内に生息する腸内細菌の分類とモニタリング法の確立

    • Principal Investigator
      伊藤 喜久治
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  Molecular mechanism of invasion of epithelial cells by ShigellaPrincipal Investigator

    • Principal Investigator
      SASAKAWA Chihiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  赤痢菌ビルレンス発現調節の分子機構

    • Principal Investigator
      YOSHIKAWA Masanosuke
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  Molecular genetical study of low-temperature growth in Listeria monocytogenes

    • Principal Investigator
      MAKINO Sou-ichi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Obihiro University of Agricuruture and Veterinary Medicine
      国立公衆衛生院
  •  Analysis of molecular mechanisms of invasion of epithelial cells by ShigellaPrincipal Investigator

    • Principal Investigator
      SASAKAWA Chihiro
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokyo
  •  Developement of live attenuated anti-Shigella vaccine based on molecular pathogenesis studies

    • Principal Investigator
      YOSHIKAWA Masanosuke
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokyo
  •  Molecular Genetics of Micrbial Pathogenesis

    • Principal Investigator
      TERAWAKI Yoshiro
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      細菌学
    • Research Institution
      Shinshu University
  •  The significance of Chromosomal Virulence Genes of Shigella flexneri in the Pathogenesis of Bacillary Dysentery

    • Principal Investigator
      YOSHIKAWA Masanosuke
    • Project Period (FY)
      1989 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokyo
  •  The Roles of the Virulence Factors of Shigella Flexneri in Cell to Cell Spread.Principal Investigator

    • Principal Investigator
      SASAKAWA Chihiro
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokyo
  •  腸管系病原性大腸菌染色体DNAの分子遺伝学的特性の解析Principal Investigator

    • Principal Investigator
      笹川 千尋
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokyo
  •  Molecular Genetic Studies on Bacterial Pathogenicity

    • Principal Investigator
      YOSHIKAWA Masanosuke
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokyo
  •  Structure and Function of the plasmid genes associated with epethelial invasion in Shigella Flexneri

    • Principal Investigator
      YOSHIKAWA Masanosuke
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      細菌学
    • Research Institution
      University of Tokyo
  •  New Tn5 variants with various drug resistance markers and suicide vector for transposon mutagenesisPrincipal Investigator

    • Principal Investigator
      SASAKAWA Chihiro
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      University of Tokyo

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2003 Other

All Journal Article Presentation Book

  • [Book] 実験医学増刊 感染・共生・生体防御システム2012

    • Author(s)
      笹川千尋
    • Total Pages
      222
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Book] 実験医学増刊 感染症・ウイルス・細菌・寄生虫の感染戦略2009

    • Author(s)
      芦田浩、笹川千尋
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Book] Autophagy in Immunity and infection2006

    • Author(s)
      Ogawa, M., Sasakawa, C.
    • Total Pages
      250
    • Publisher
      WILEY-VCH
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021011
  • [Book] 解明が進むウィルス・細菌 感染と免疫応答2006

    • Author(s)
      小川道永, 笹川千尋
    • Total Pages
      226
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021011
  • [Book] Bacterial Invasion of Host Cells2003

    • Author(s)
      Sasakawa, Chihiro
    • Publisher
      CAMBRIDGE UNIVERSITY PRESS
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021011
  • [Journal Article] Molecular mechanisms regulating NLRP3 inflammasome activation.2016

    • Author(s)
      Jo EK, Kim JK, Shin DM, Sasakawa C.
    • Journal Title

      Cell Mo1 Immunol.

      Volume: 13 Issue: 2 Pages: 148-159

    • DOI

      10.1038/cmi.2015.95

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] Shigella IpaH family effectors as a versatile model for studying pathogenic bacteria2016

    • Author(s)
      Ashida H & Sasakawa C
    • Journal Title

      Front Cell. Infect. Microbiol

      Volume: 5 Pages: 100-100

    • DOI

      10.3389/fcimb.2015.00100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-23000012
  • [Journal Article] Crystal structure of the substrate-recognition domain of the Shigella E3 ligase IpaH9.8.2016

    • Author(s)
      Takagi K, Kim M, Sasakawa C, Mizushima T.
    • Journal Title

      Acta Crystallographica Section F.

      Volume: F72 Issue: 4 Pages: 269-275

    • DOI

      10.1107/s2053230x16003794

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] A Midori-ishi Cyan/monomeric Kusabira-Orange-based fluorescence resonance energy transfer assay for characterization of various E3 ligases.2016

    • Author(s)
      Otsubo R, Kim M, Lee J, Sasakawa C.
    • Journal Title

      Genes to Cells

      Volume: 21

    • Description
      【掲載確定】 印刷中
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] Shigella manipulates host immune responses by delivering effector proteins with specific roles2015

    • Author(s)
      Ashida H, Mimuro H, & Sasakawa C
    • Journal Title

      Front Immunol

      Volume: 6 Pages: 219-219

    • DOI

      10.3389/fimmu.2015.00219

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-26293095, KAKENHI-PROJECT-23000012
  • [Journal Article] Bacterial Effectors and Their Functions in the Ubiquitin-Proteasome System: Insight from the Modes of Substrate Recognition2014

    • Author(s)
      Kim M et. al
    • Journal Title

      Cells

      Volume: 3 Issue: 3 Pages: 848-864

    • DOI

      10.3390/cells3030848

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-14J10879, KAKENHI-PROJECT-23000012, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25870631
  • [Journal Article] Disease severity is associated with differential gene expression at the early and late phases of infection in nonhuman primates infected with different H5N1 highly pathogenic avian influenza viruses.2014

    • Author(s)
      Muramoto Y, Shoemaker JE, Le MQ, Itoh Y, Tamura D, Sakai-Tagawa Y, Imai H, Uraki R, Takano R, Kawakami E, Ito M, Okamoto K, Ishigaki H, Mimuro H, Sasakawa C, Matsuoka Y, Noda T, Fukuyama S, Ogasawara K, Kitano H, Kawaoka Y.
    • Journal Title

      Journal of Virlogy

      Volume: 88(16) Issue: 16 Pages: 8981-8997

    • DOI

      10.1128/jvi.00907-14

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J01509, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23590145, KAKENHI-PROJECT-25670216, KAKENHI-PROJECT-26293095, KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-26850180
  • [Journal Article] Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkc δ.2014

    • Author(s)
      Suzuki S, Franchi L, He Y, Muioz-Planillo R, Mimuro H, Suzuki T, Sasakawa C, Nunez G.
    • Journal Title

      PLoS Pathog.

      Volume: 10 Issue: 2 Pages: e1003926-e1003926

    • DOI

      10.1371/journal.ppat.1003926

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23390106, KAKENHI-PROJECT-24659201, KAKENHI-PROJECT-26860283
  • [Journal Article] Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection2014

    • Author(s)
      Kiga K et.al
    • Journal Title

      Nat Commun

      Volume: 5 Issue: 1 Pages: 4497-4497

    • DOI

      10.1038/ncomms5497

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390329, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460555, KAKENHI-PROJECT-25670209, KAKENHI-PROJECT-25830134, KAKENHI-PROJECT-26293095
  • [Journal Article] Comprehensive silencing of target-sharing microRNAs is a mechanism for SIRT1 overexpression in cancer2014

    • Author(s)
      Kiga K, Fukuda-Yuzawa Y, Tanabe M, Tsuji S, Sasakawa C, Fukao T
    • Journal Title

      RNA Biol

      Volume: 11 Issue: 11 Pages: 1347-54

    • DOI

      10.4161/rna.32093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] Shigella hacks host immune responses by reprogramming the host epigenome2014

    • Author(s)
      Ashida H, Sasakawa C
    • Journal Title

      EMBO J

      Volume: 33 Issue: 22 Pages: 2598-600

    • DOI

      10.15252/embj.201489934

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-25460527
  • [Journal Article] Innate lymphoid cells regulate intestinal epithelial cell glycosylation.2014

    • Author(s)
      Goto Y, Obata T, Kunisawa J, Sato S, Ivanov II, Lamichhane A, Takeyama N, Kamioka M, Sakamoto M, Matsuki T, Uematsu S, Akira S, Domino SE, Kulig P, Becher B, Renauld JC, Sasakawa C, Umesaki Y, Benno Y, Kiyono H
    • Journal Title

      Science

      Volume: 345 Issue: 6202 Pages: 1254009-1254009

    • DOI

      10.1126/science.1254009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-24590582, KAKENHI-PROJECT-25860353, KAKENHI-PROJECT-26293111, KAKENHI-PROJECT-19H03465
  • [Journal Article] Exploitation of the host ubiquitin system by human bacterial pathogens2014

    • Author(s)
      Ashida H et. al
    • Journal Title

      Nat Rev Microbiol

      Volume: 12 Issue: 6 Pages: 399-413

    • DOI

      10.1038/nrmicro3259

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711
  • [Journal Article] Manipulation of the host cell death pathway by Shigella2014

    • Author(s)
      Ashida H, Kim M, Sasakawa C
    • Journal Title

      Cell Microbiol

      Volume: 16 Issue: 12 Pages: 1757-66

    • DOI

      10.1111/cmi.12367

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-25460527
  • [Journal Article] Shigella IpaH7.8 E3 ligase targets glomulin and activates inflammasomes to demolish macrophages2014

    • Author(s)
      Suzuki S et.al
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 111 Issue: 40

    • DOI

      10.1073/pnas.1324021111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25460555, KAKENHI-PROJECT-26293095, KAKENHI-PROJECT-26860283
  • [Journal Article] Roles of autophagy in elimination of intracellular bacterial pathogens.2013

    • Author(s)
      Jo EK, Yuk JM, Shin DM, Sasakawa C.
    • Journal Title

      Front Immunol.

      Volume: 4

    • DOI

      10.3389/fimmu.2013.00097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] The Shigella OspC3 effector inhibits Cspase-4, antagonizes inflammatory cell death, and promotes epithelial infection2013

    • Author(s)
      Kobayashi T, et. al
    • Journal Title

      Cell Host Microbe

      Volume: 13 Issue: 5 Pages: 570-583

    • DOI

      10.1016/j.chom.2013.04.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471, KAKENHI-PUBLICLY-24117507, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25460555
  • [Journal Article] Autophagy controls an intrinsic host defense to bacteria by promoting epithelial cell survival : a murine model.2013

    • Author(s)
      Chang SY, Lee SN, Yang JY, Kim DW, Yoon JH, Ko HJ, Ogawa M, Sasakawa C, Kweon MN.
    • Journal Title

      PLoS One.

      Volume: 8 Issue: 11 Pages: e81095-e81095

    • DOI

      10.1371/journal.pone.0081095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-25460555
  • [Journal Article] 赤痢菌による自然免疫の抑制機構2013

    • Author(s)
      真田 貴人、笹川 千尋
    • Journal Title

      感染・炎症・免疫

      Volume: 43 Pages: 168-169

    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] 赤痢菌感染分子基盤戦略の解明2013

    • Author(s)
      芦田 浩、笹川 千尋
    • Journal Title

      感染・炎症・免疫

      Volume: 43 Pages: 135-144

    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] Shigella IpaH0722 E3 ubiquitin ligase effector targets TRAF2 to inhibit PKC-NF-κB activity in invaded epithelial cells.2013

    • Author(s)
      Ashida H, Nakano H, Sasakawa C.
    • Journal Title

      PLoS Pathog.

      Volume: 9 Issue: 6 Pages: e1003409-e1003409

    • DOI

      10.1371/journal.ppat.1003409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-24390100, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25670167
  • [Journal Article] 赤痢菌の病原性の研究:粘膜バリアーにおける病原体と宿主の相互作用の研究2012

    • Author(s)
      笹川千尋
    • Journal Title

      日本細菌学雑誌

      Volume: 67 Pages: 257-268

    • NAID

      10031156164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response2012

    • Author(s)
      Sanada, T.
    • Journal Title

      Nature

      Volume: 483 Issue: 7391 Pages: 623-626

    • DOI

      10.1038/nature10894

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22117001, KAKENHI-PLANNED-22117002, KAKENHI-PROJECT-22790403, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-23121525, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23770203, KAKENHI-PROJECT-23790471
  • [Journal Article] Shigella are versatile mucosal pathogens that circumvent the host innate immune system2011

    • Author(s)
      Ashida H., Sasakawa C., et al.
    • Journal Title

      Curr Opin Immunol

      Volume: 23 Pages: 448-455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] Shigella are versatile mucosal pathogens that circumvent the host innateimmune system.2011

    • Author(s)
      Ashida, H., Sasakawa, C., et al.
    • Journal Title

      Curr Opin Immunol.

      Volume: (In press)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] The role of Tecprl in selective autophagy as a cargo receptor2011

    • Author(s)
      Ogawa, M., Sasakawa, C., et al
    • Journal Title

      Autophagy

      Volume: 7(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] The role of Tecpr1 in selective autophagy as a cargo receptor2011

    • Author(s)
      Ogawa M., Sasakawa C.
    • Journal Title

      Autophagy

      Volume: 7 Pages: 1389-1391

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] Shigella deploy multiple countermeasures against host innate immune responses.2011

    • Author(s)
      Ashida H, Ogawa M, Kim M, Suzuki S, Sanada T, Punginelli C, Mimuro H, Sasakawa C.
    • Journal Title

      Curr Opin Microbiol. 14

      Pages: 16-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Bacteria and host interactions in the gut epithelial barrier2011

    • Author(s)
      Ashida H., Sasakawa C., et al.
    • Journal Title

      Nat Chem Biol

      Volume: 8 Issue: 1 Pages: 36-45

    • DOI

      10.1038/nchembio.741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471
  • [Journal Article] Shigella deploy multiple countermeasures against host innate immune responses.2011

    • Author(s)
      Ashida, H., Sasakawa, C., et al.
    • Journal Title

      Curr Opin Microbiol.

      Volume: 14 Pages: 16-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] l death and infection : a double-edged sword for host and pathogen surviv2011

    • Author(s)
      Ashida, H., Sasakawa, C., et al
    • Journal Title

      Journal of cell biology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] BabA-mediated adherence is a potentiator of the Helicobacter pylori Type IV secretion system activity.2011

    • Author(s)
      Ishijima N, Suzuki M, Ashida H, Ichikawa Y, Kanegae Y, Saito I, Boren T, Haas R, Sasakawa C, Mimuro H.
    • Journal Title

      J Biol Chem. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Shigella deploy multiple countermeasures against host innate immune responses.2011

    • Author(s)
      Ashida, H., Sasakawa, C., et al.
    • Journal Title

      Curr Opin Microbiol.

      Volume: 14 Pages: 16-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Manipulation of autophagy by bacteria for their own benefit2011

    • Author(s)
      Ogawa, M., Sasakawa, C., et al
    • Journal Title

      Microbiol Immunol

      Volume: 55 Pages: 459-71

    • NAID

      10031121491

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Manipulation of autophagy by bacteria for their own benefit2011

    • Author(s)
      Ogawa M.
    • Journal Title

      Microbiology and Immunology

      Volume: VOL.55 Issue: 7 Pages: 459-471

    • DOI

      10.1111/j.1348-0421.2011.00343.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22890154, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23790471
  • [Journal Article] A tecpr1-dependent selective autophagy pathway targets bacterial pathogens.2011

    • Author(s)
      Ogawa M, Yoshikawa Y, Kobayashi T, Mimuro H, Fukumatsu M, Kiga K, Piao Z, Ashida H, Yoshida M, Kakuta S, Koyama T, Goto Y, Nagatake T, Nagai S, Kiyono H, Kawalec M, Reichhart JM, Sasakawa C.
    • Journal Title

      Cell Host Microbe. 9

      Pages: 376-389

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Attenuated CagA oncoprotein in Helicobacter pylori from Amerindians in Peruvian Amazon2011

    • Author(s)
      Suzuki M., Sasakawa C., et al.
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 29964-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] BabA-mediated adherence is a potentiator of the Helicobacter pylori type IV secretion system activity2011

    • Author(s)
      Ishijima N., Sasakawa C, Mimuro H., et al.
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 25256-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] Cell death and infection : a double-edged sword for host and pathogen survival2011

    • Author(s)
      Ashida H., Sasakawa C., et al.
    • Journal Title

      J Cell Biol

      Volume: 195 Pages: 931-942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Journal Article] Shigella are versatile mucosal pathogens that circumvent the host innate immune system.2011

    • Author(s)
      Ashida, H., Sasakawa, C., et al.
    • Journal Title

      Curr Opin Immunol.

      Volume: (in press)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Bacterial interactions with the host epithelium.2010

    • Author(s)
      Kim M., Sasakawa, C., et al.
    • Journal Title

      Cell Host Microbe.

      Volume: 8 Pages: 20-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] A bacterial E3 ubiquitin ligase lpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response.2010

    • Author(s)
      Ashida, H., Sasakawa, C., et al.
    • Journal Title

      Nat.Cell Biol 12

      Pages: 66-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response2010

    • Author(s)
      Ashida, H., Sasakawa, C., et al.
    • Journal Title

      Nat.Cell Biol 12

      Pages: 66-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] A new paradigm of bacteria-gut interplay brought through the study of Shigella2010

    • Author(s)
      Sasakawa, C.
    • Journal Title

      Proc.of the Japan Academy, Ser.B 86

      Pages: 229-243

    • NAID

      130000264076

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Bacterial interactions with the host epithelium.2010

    • Author(s)
      Kim M, Ashida H, Ogawa M, Yoshikawa Y, Mimuro H, Sasakawa C.
    • Journal Title

      Cell Host Microbe. 8

      Pages: 20-35

    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Bacterial interactions with the host epithelium.2010

    • Author(s)
      Kim M, Ashida H, Ogawa M, Yoshikawa Y, Mimuro H, Sasakawa C.
    • Journal Title

      Cell Host Microbe. 8

      Pages: 20-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Bacterial interactions with the host epithelium.2010

    • Author(s)
      Kim M., Sasakawa, C., et al.
    • Journal Title

      Cell Host Microbe.

      Volume: 8 Pages: 20-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response.2010

    • Author(s)
      Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C.
    • Journal Title

      Nat Cell Biol. 12

      Pages: 66-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response.2010

    • Author(s)
      Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C.
    • Journal Title

      Nat Cell Biol. 12

      Pages: 66-73

    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Reinforcement of epithelial cell adhesion to basement membrane by a bacterial pathogen as a new infectious stratagem2010

    • Author(s)
      Kim, M., Sasakawa, C., et al.
    • Journal Title

      Virulence 1

      Pages: 52-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Shigella infection of intestinal epithelium and circumvention of the host innate defense system.2009

    • Author(s)
      Ashida, H., Sasakawa, C., et al.
    • Journal Title

      Curr.Top.Microbiol.Immunol 337

      Pages: 231-255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment.2009

    • Author(s)
      Kim M, Ogawa M, Fujita Y, Yoshikawa Y, Nagai T, Koyama T, Nagai S, Lange A, Fassler R, Sasakawa C.
    • Journal Title

      Nature 459

      Pages: 578-582

    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Listeria monocytogenes ActA-mediated escape from autophagic recognition.2009

    • Author(s)
      Yoshikawa Y, Ogawa M, Hain T, Yoshida M, Fukumatsu M, Kim M, Mimuro H, Nakagawa I, Yanagawa T, Ishii T, Kakizuka A, Sztul E, Chakraborty T, Sasakawa C.
    • Journal Title

      Nat Cell Biol. 11

      Pages: 1233-1240

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article]2009

    • Author(s)
      芦田浩、笹川千尋
    • Journal Title

      実験医学増刊感染症・ウイルス・細菌・寄生虫の感染戦略(羊土社)

      Pages: 199-204

    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Shigella infection of intestinal epithelium and circumvention of the host innate defense system2009

    • Author(s)
      Ashida, H., Sasakawa, C., et al.
    • Journal Title

      Curr.Top.Microbiol.Immunol 337

      Pages: 231-255

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Streptococcus-, Shigella-, and Listeria-induced autophagy.2009

    • Author(s)
      Ogawa, M., Sasakawa, C., et al.
    • Journal Title

      Methods Enzymol 452

      Pages: 363-381

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Listeria monocytogenes ActA-Mediated escape from autophagic recognition.2009

    • Author(s)
      Yoshikawa, Y., Sasakawa, C., et al.
    • Journal Title

      Nat.Cell Biol 11

      Pages: 1233-1240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Listeria monocytogenes ActA is a key player in evading autophagic recognition.2009

    • Author(s)
      Yoshikawa, Y., Sasakawa, C., et al.
    • Journal Title

      Autophagy 5

      Pages: 1220-1221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Helicobacter pylori CagA phosphorylation-independent function in epithelial proliferation and inflammation.2009

    • Author(s)
      Suzuki M, Mimuro H, Kiga K, Fukumatsu M, Ishijima N, Morikawa H, Nagai S, Koyasu S, Gilman RH, Kersulyte D, Berg DE, Sasakawa C.
    • Journal Title

      Cell Host Microbe. 5

      Pages: 23-34

    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment.2009

    • Author(s)
      Kim, M., Sasakawa, C., et al.
    • Journal Title

      Nature 459

      Pages: 578-582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment.2009

    • Author(s)
      Kim M, Ogawa M, Fujita Y, Yoshikawa Y, Nagai T, Koyama T, Nagai S, Lange A, Fassler R, Sasakawa C.
    • Journal Title

      Nature. 459

      Pages: 578-582

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Shigella infection of intestinal epithelium and circumvention of the host innate defense system.2009

    • Author(s)
      Ashida H, Ogawa M, Mimuro H, Sasakawa C.
    • Journal Title

      Curr Top Microbiol Immunol. 337

      Pages: 231-255

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Streptococcus-, Shigella-, and Listeria-induced autophagy2009

    • Author(s)
      Ogawa, M., Sasakawa, C., et al.
    • Journal Title

      Methods Enzymol 452

      Pages: 363-381

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment2009

    • Author(s)
      Kim, M., Sasakawa, C., et al.
    • Journal Title

      Nature 459

      Pages: 578-582

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Listenia monocytogenes ActA is a key player in evading autophagic recognition2009

    • Author(s)
      Yoshikawa, Y., Sasakawa, C., et al.
    • Journal Title

      Autophagy 5

      Pages: 1220-1221

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Listeria monocytogenes ActA-mediated escape from autophagic recognition2009

    • Author(s)
      Yoshikawa, Y., Sasakawa, C., et al.
    • Journal Title

      Nat.Cell Biol 11

      Pages: 1233-1240

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Listeria monocytogenes ActA-mediated escape from autophagic recognition.2009

    • Author(s)
      Yoshikawa Y, Ogawa M, Hain T, Yoshida M, Fukumatsu M, Kim M, Mimuro H, Nakagawa I, Yanagawa T, Ishii T, Kakizuka A, Sztul E, Chakraborty T, Sasakawa C.
    • Journal Title

      Nat Cell Biol. 11

      Pages: 1233-1240

    • Data Source
      KAKENHI-PROJECT-20229006
  • [Journal Article] The versatility of Shigella effectors.2008

    • Author(s)
      Ogawa, M., Handa, Y., Ashida, H., Suzuki, M., Sasakawa, C.
    • Journal Title

      Nat. Rev. Microbiol. 6

      Pages: 11-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Shigella IpgB1 promotes bacterial entry through the ELMO-Dock 180 machinery.2007

    • Author(s)
      Handa Y, Suzuki M, Ohya K, Iwai H, Ishijima N, Koleske A.J, Fukui Y, Sasakawa C.
    • Journal Title

      Nat Cell Biol 9

      Pages: 121-128

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] A Bacterial Effector Targets Mad2L2, an APC Inhibitor2007

    • Author(s)
      Iwai, H., Kim, M., Yoshikawa, Y., Ashida, H., Ogawa, M., Fujita, Y., Muller, D., Kirikae, T., Jackson, P.K., Kotani, S., Sasakawa, C.
    • Journal Title

      Modulate Host Cell Cycling. Cell 130

      Pages: 611-623

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] A bacterial Effector Targets Mad2L2, an APC Inhibitor, to Modulate Host Cell Cycling.2007

    • Author(s)
      Iwai H, Kim M, Yoshikawa Y, Ashida H, Ogawa M, Fujita Y, Muller D, Kirikae T, Jackson P.K, Kotani S.Sasakawa C.
    • Journal Title

      Cell 130

      Pages: 611-623

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Shigella and Autophagy.2006

    • Author(s)
      Ogawa, M., Sasakawa, C.
    • Journal Title

      Autophagy 2

      Pages: 171-174

    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery.2006

    • Author(s)
      Handa, Y., Suzuki, M., Ohya, K., Iwai, H., Ishijima, N., Koleske, A.J., Fukui Y., Sasakawa, C.
    • Journal Title

      Nat. Cell Biol. 9

      Pages: 121-128

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Intracellular survival of Shigella.2006

    • Author(s)
      Ogawa, M., Sasakawa, C.
    • Journal Title

      Cell.Microbiol 8

      Pages: 177-184

    • Data Source
      KAKENHI-PROJECT-14021011
  • [Journal Article] Intracellular survival of Shigella.2006

    • Author(s)
      Ogawa, M., Sasakawa, C.
    • Journal Title

      Cell. Microbiol. 8

      Pages: 177-184

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021011
  • [Journal Article] New Animal Model of Shigellosis in the Guinea Pig : Its Usefulness for Protective Efficacy Studies.2006

    • Author(s)
      Shim D.H., Suzuki T., Chang S.Y., Park S.M., Sansonetti P.J., Sasakawa C., Kweon M.N.
    • Journal Title

      J. Immunol. 178

      Pages: 2476-2482

    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] EspF of Enteropathogenic Escherichia coli Binds Sorting Nexin 9.2006

    • Author(s)
      Marches, O., Sasakawa, C., et al.
    • Journal Title

      J. Bacteriol. 188

      Pages: 3110-3115

    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Bacterial evasion of the autophagic defense system.2006

    • Author(s)
      Ogawa, M., Sasakawa, C.
    • Journal Title

      Curr. Opin. Microbiol. 9

      Pages: 62-68

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021011
  • [Journal Article] Bacterial evasion of the autophagic defense system.2006

    • Author(s)
      Ogawa, M., Sasakawa, C.
    • Journal Title

      Curr.Opin.Microbiol. 9

      Pages: 62-68

    • Data Source
      KAKENHI-PROJECT-14021011
  • [Journal Article] Intracellular survival of Shigella.2006

    • Author(s)
      Ogawa, M., Sasakawa, C.
    • Journal Title

      Cell. Microbiol 8

      Pages: 177-184

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021011
  • [Journal Article] Microtubule-severing activity of Shigella is pivotal for intercellular spreading.2006

    • Author(s)
      Yoshida S, Handa Y, Suzuki T, Ogawa M, Suzuki M, Tamai A, Abe A, Katayama E, Sasakawa C.
    • Journal Title

      Science 314

      Pages: 985-989

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] High vaccine efficacy against shigellosis of recombinant noninvasive Shigella mutant that expresses Yersinia invasin.2006

    • Author(s)
      Suzuki, T., Yoshikawa, Y., Ashia, H., Iwai, H., Toyotome, T., Matsui, H., Sasakawa, C.
    • Journal Title

      J. Immunol. 177

      Pages: 4709-4717

    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Shigella chromosomal IpaH proteins are secreted via the type III secretion system and act as effectors.2006

    • Author(s)
      Ashida, H., Toyotome, T., Nagai, T., Sasakawa, C.
    • Journal Title

      Mol. Microbiol. 63

      Pages: 680-693

    • Data Source
      KAKENHI-PLANNED-18073003
  • [Journal Article] Shigella Spa33 is an essential C-ring component of type III secretion machinery.2005

    • Author(s)
      Morita-Ishihara, T., Ogawa, M., Sagara, H., Yoshida, M., Katayama, E., Sasakawa, C.
    • Journal Title

      J.Biol.Chem. 281

      Pages: 599-607

    • Data Source
      KAKENHI-PROJECT-14021011
  • [Journal Article] IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells : ITS ACTIVITY TO PROMOTE MEMBRANE RUFFLING VIA RAC1 AND CDC42 ACTIVATION.2005

    • Author(s)
      Ohya K., Handa Y., Ogawa M., Suzuki, M., Sasakawa, C.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 24022-24034

    • Data Source
      KAKENHI-PROJECT-14021011
  • [Journal Article] Targeting of enteropathogenic Escherichia coli EspF to host mitochondria is essential for the bacterial pathogenesis : critical role of the 16th leucine residue in EspF.2005

    • Author(s)
      Nagai, T., Abe, A., Sasakawa, C.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 2998-3011

    • Data Source
      KAKENHI-PROJECT-14021011
  • [Journal Article] Exploiting host microtubule dynamics : a new aspect of bacterial invasion.2003

    • Author(s)
      Yoshida, S., Sasakawa, C.
    • Journal Title

      Trends in Microbiol. 11

      Pages: 139-143

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021011
  • [Journal Article] Exploiting host microtubule dynamics : a new aspect of bacterial invasion.2003

    • Author(s)
      Yoshida, S., Sasakawa, C.
    • Journal Title

      Trend in Microbiol. 11

      Pages: 139-143

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021011
  • [Presentation] Shigella manipulates host immune responses by delivering effector proteins with specific roles.2015

    • Author(s)
      Hiroshi Ashida, Chihiro Sasakawa
    • Organizer
      The 14th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路夢舞台国際会議場(兵庫県・淡路市)
    • Year and Date
      2015-09-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Shigella, a prominent DAMPs creator, deploy multiple systems to modulate host innate immune responses.2015

    • Author(s)
      Chihiro Sasakawa
    • Organizer
      Damage-associated molecular patterns & Innate immunity (WRII)
    • Place of Presentation
      Seuol (Korea)
    • Year and Date
      2015-10-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Shigella manipulates host immune responses by delivering IpaH effector2015

    • Author(s)
      Hiroshi Ashida, Chihiro Sasakawa
    • Organizer
      COLD SPRING HARBOR ASIA CONFERENCES
    • Place of Presentation
      Suzhou(China)
    • Year and Date
      2015-11-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Shigella deploy multiple systems to modulate host innate immune responses2015

    • Author(s)
      Chihiro Sasakawa
    • Organizer
      COLD SPRING HARBOR ASIA CONFERENCES
    • Place of Presentation
      Suzhou(China)
    • Year and Date
      2015-11-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Shigella Type Ⅲ Secretion protein MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation2014

    • Author(s)
      Shiho Suzuki, Luigi Franchi, Yuan He, Hitomi Mimuro, Chihiro Sasakawa, Gabriel Núñez
    • Organizer
      日米コレラ部会(日米医学協力研究会コレラ・細菌性腸管感染症専門部会)日本側総会
    • Place of Presentation
      京都大学稲森財団記念館(京都府京都市)
    • Year and Date
      2014-08-07
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] The role of type III effetor during the mucosal pathogenic bacteria infection OspE shares a general role in bacterial infection2014

    • Author(s)
      Hanako Morikawa, Keiko Ono, Ai Himeno, Chihiro Sasakawa, Minsoo Kim
    • Organizer
      International Union of Microbiological Societies Congresses 2014
    • Place of Presentation
      モントリオールコンベンションセンター(カナダ・モントリオール)
    • Year and Date
      2014-07-29
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] TR-FRET-based High-Throughput screening assay for identification of bacterial ubiquitin ligase inhibitor2014

    • Author(s)
      Minsoo Kim, Shinchiro Egashira2 Hiroki Sakamoto3 Keiko Ono, Chihiro Sasakawa, Takayoshi Okabe
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-27
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Shigella MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation2014

    • Author(s)
      Suzuki S, Mimuro H, Kim M, Núñez G, Sasakawa C
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-27
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] 赤痢菌感染におけるNlrc4 inflammasome活性化の機構2014

    • Author(s)
      鈴木志穂、三室仁美、笹川千尋、Gabriel Nunez
    • Organizer
      第97回日本細菌学会関東支部総会
    • Place of Presentation
      東京ドームホテル(東京都文京区)
    • Year and Date
      2014-10-30
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Bacteria and gut interplay : Circumvention of intestinal mucosal barriers by Shigella2013

    • Author(s)
      Chihiro Sasakawa
    • Organizer
      France-Japan Joint Forum "Frontiers in Innate Immunity"
    • Place of Presentation
      ストラスブール大学(フランス・ストラスブール)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Shigella manipulation of mucosal barriers2012

    • Author(s)
      Chihiro Sasakawa
    • Organizer
      VTEC2012
    • Place of Presentation
      Amsterdam (Netherlands)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Shigella circumvention of the gut mucosal barriers2012

    • Author(s)
      Chihiro Sasakawa
    • Organizer
      THE 34th NAITO CONFERENCE ON Infection, Immunity and their Control for Health: Mucosal Barrier, Pathogen and Vaccine
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ(北海道)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] New insights into Shigella-gut epithelial interaction2011

    • Author(s)
      Sasakawa, C.
    • Organizer
      Todai Forum 2011 'Forum on Systems Biology & Genomic Medicine'
    • Place of Presentation
      Paris, France(招待講演)
    • Year and Date
      2011-10-18
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] New Insights into Shigella-gut Epithelial Interaction2011

    • Author(s)
      Sasakawa, C.
    • Organizer
      2011 International Meeting of FKMS
    • Place of Presentation
      Seoul, Korea(招待講演)
    • Year and Date
      2011-10-13
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Regulation of bacterial colonization on gastric epithelium by Helicobacterpylori virulence factors2010

    • Author(s)
      Mimuro H, Ishijima N, Sasakawa C.
    • Organizer
      The 10th Awaji International Forum on Infection andimmunity
    • Place of Presentation
      Awaji Yumebutai International Conference Center
    • Year and Date
      2010-09-08
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] The bacterial effector Cif interferes with SCF ubiquitin ligase function by inhibiting deneddylation of Cullin12010

    • Author(s)
      Morikawa H., Sasakawa C., et al.
    • Organizer
      BMB2010
    • Place of Presentation
      Kobe, Japan 神戸ポートアイランド
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] New insights into Shigella-gut epithelium interaction2010

    • Author(s)
      Sasakawa, C.
    • Organizer
      AHMR Forum-Health and medical research in the Asia Pacific region : the opportunities, the possibilities, the challenges
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] New insights into Shigella-gut epithelium interaction2010

    • Author(s)
      Sasakawa C.
    • Organizer
      AHMR Forum 2010-Health and medical research in the Asia Pacific region : the opportunities, the possibilities, the challenges.
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Regulation of host cell turn-over by bacterial ubiquitin ligase, lpaH4.52010

    • Author(s)
      Kim M, Sasakawa C.
    • Organizer
      BMB2010
    • Place of Presentation
      Kobe, JapanAP神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] New insights into Shigella-gut epithelium interaction2010

    • Author(s)
      Sasakawa, C.
    • Organizer
      ASMR Forum-Health and medical research in the Asia Pacific region : the opportunities, the possibilities
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Effect of Helicobacter pylori's BabA adhesion on the pathogenicity in gastric epithelial cells2010

    • Author(s)
      Hitomi Mimuro, Nozomi Ishijima, Chihiro Sasakawa
    • Organizer
      The 10th Japan-Korea international symposium on microbiology, JKISM10
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] A bacterial E3 ubiquitin ligase IpaH9.8 effector targets NEMO/IKKg to dampen the host NF-kB-mediated inflammatory response2010

    • Author(s)
      Hiroshi Ashida, Chihiro Sasakawa
    • Organizer
      The 10th Japan-Korea international symposium on microbiology, JKISM10
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Listeria monocytogenes ActA-mediated escape from autophagic recognition.2010

    • Author(s)
      Yuko Yoshikawa, Chihiro Sasakawa
    • Organizer
      The 10th Japan-Korea international symposium on microbiology, JKISM10
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] New insights into Shigella-gut epithelium interaction2010

    • Author(s)
      Sasakawa, C.
    • Organizer
      Embo Workshop, Emerging Themes in infectionBiology
    • Place of Presentation
      Nice, France
    • Year and Date
      2010-06-02
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] New insights into Shigella-gut epithelium interaction2010

    • Author(s)
      Sasakawa, C
    • Organizer
      Embo Workshop, Emerging Themes in Infection Biology
    • Place of Presentation
      Nice, France
    • Year and Date
      2010-06-02
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] New insights into Shigella-gut epithelium interaction.2010

    • Author(s)
      Sasakawa, C.
    • Organizer
      Embo Workshop, Emerging Themes in infectionBiology.
    • Place of Presentation
      Nice, France
    • Year and Date
      2010-06-02
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Regulation of host cell turn-over by bacterial ubiquitin ligase, IpaH4.5c2010

    • Author(s)
      Kim M., Sasakawa C., et al.
    • Organizer
      ASMR Forum-Health and medical research in the Asia Pacific region : the opportunities, the possibilities, he challenges
    • Place of Presentation
      Vermont, U.S.A
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Regulation of bacterial colonization on gastric epithelium by Helicobacter pylori virulence factors2010

    • Author(s)
      Mimuro H, Ishijima N, Sasakawa C.
    • Organizer
      The 10th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji Yumebutai International Conference Center
    • Year and Date
      2010-09-08
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] The bacterial effector Cif interferes with SCF ubiquitin ligase function by inhibiting deneddylation of Cullin12010

    • Author(s)
      Morikawa H.Sasakawa C.
    • Organizer
      BMB2010
    • Place of Presentation
      Kobe, Japan神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Ospl, shigella Type III effector, negatively regulates NF-kappaB and MAPK pathway2010

    • Author(s)
      Takahito Sanada, Chihiro Sasakawa, et al.
    • Organizer
      The 10th Japan-Korea international symposium on microbiology, JKISM10
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] New insights into Shigella-gut epithelium interaction2010

    • Author(s)
      Sasakawa C.
    • Organizer
      Embo Workshop, Emerging Themes in infection Biology
    • Place of Presentation
      Nice, France
    • Year and Date
      2010-06-02
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] A bacterial E3 ubiquitin ligase lpanH9.8 effector targets NEMO/IKKg to dampen the host NF-kB-mediated inflammatory response.2010

    • Author(s)
      Hiroshi Ashida, Chihiro Sasakawa
    • Organizer
      The 10th Japan-Korea international symposium on microbiology, JKISM10
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Regulation of host cell turn-over by bacterial ubiquitin ligase, IpaH4.52010

    • Author(s)
      Kim M.Sasakawa C., et al.
    • Organizer
      2010 FASEB summer research conferences
    • Place of Presentation
      Vermont, U.S.A
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Analysis of the Shigella typelll effector protein required for macrophage pyroptosis.2010

    • Author(s)
      Shiho Suzuki, Chihiro Sasakawa, et al.
    • Organizer
      The 10th Japan-Korea international symposium on microbiology, JKISM10
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Regulation of host cell turn-over by bacterial ubiquitin ligase, IpaH4.52010

    • Author(s)
      Kim M., Sasakawa C., et al.
    • Organizer
      BMB2010
    • Place of Presentation
      Kobe, Japan 神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Regulation of host cell turn-over by bacterial ubiquitin ligase, IpaH4.52010

    • Author(s)
      Kim M., Sasakawa C., et al.
    • Organizer
      2010 International chemical congress of pacific basin societies
    • Place of Presentation
      Honolulu, U.S.A
    • Year and Date
      2010-12-19
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Ospl, shigella Type III effector, negatively regulates NF-kappaB and MAPK pathway2010

    • Author(s)
      Takahito Sanada, Chihiro Sasakawa, et al.
    • Organizer
      The 10th Japan-Korea international symposium on microbiology, JKISM10
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Regulation of host homeostasis by bacterial ubiquitin ligases2010

    • Author(s)
      Kim M, Ashida H, Sasakawa C.
    • Organizer
      2010 International chemical congress of pacific basin societies
    • Place of Presentation
      Honolulu, U.S.A
    • Year and Date
      2010-12-19
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Analysis of the Shigella typeIII effector protein required for macrophage pyroptosis2010

    • Author(s)
      Shiho Suzuki, Chihiro Sasakawa, et al.
    • Organizer
      The 10th Japan-Korea international symposium on microbiology, JKISM10
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella circumvention of intestinal innate defense system2010

    • Author(s)
      Sasakawa, C.
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan 神戸ポートピアホテル
    • Year and Date
      2010-08-26
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella circumvention of intestinal innate defense system2010

    • Author(s)
      Sasakawa, C.
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      Kobe, Japan Kobe Convention center
    • Year and Date
      2010-08-26
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Listeria monocytogenes ActA-mediated escape from autophagic recognition2010

    • Author(s)
      Yuko Yoshikawa, Chihiro Sasakawa
    • Organizer
      The 10th Japan-Korea international symposium on microbiology, JKISM10
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Control of epithelial cell by Helicobacter pylori infection2009

    • Author(s)
      Hitomi Mimuro, Chihiro Sasakawa
    • Organizer
      15th International Workshop on Campylobacter, Helicobacter, and related organisms(CHRO2009)
    • Place of Presentation
      朱鷺メッセ
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Autophagy Evasion by Cytosolic Bacteria2009

    • Author(s)
      Chihiro Sasakawa
    • Organizer
      109th General Meeting of the American Society for Microbiology
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Autophagy Evasion by Cytosolic Bacteria2009

    • Author(s)
      Sasakawa C.
    • Organizer
      109^<th> General Meeting of the American Society for Microbiology
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Analysis of the Shigella typelll effector protein required for macrophage pyroptosis.2009

    • Author(s)
      Shiho Suzuki, Chihiro Sasakawa, et al.
    • Organizer
      The 9th Awaji International Forum on Infection andlmmunity
    • Place of Presentation
      Awaji Yumebutai International Conference Center
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Molecular Dialogue of bacteria with the host2009

    • Author(s)
      Sasakawa, C.
    • Organizer
      INRA-JSPS共催フォーラム
    • Place of Presentation
      INRA, France
    • Year and Date
      2009-01-30
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella Exploitation and Subversion of Host Cell Function.2009

    • Author(s)
      Chihiro Sasakawa
    • Organizer
      The 9th Awaji International Forum on Infection andlmmunity
    • Place of Presentation
      Awaji Yumebutai International Conference Center
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Analysis of the Shigella typeIII effector protein required for macrophage pyroptosis2009

    • Author(s)
      Shiho Suzuki, Chihiro Sasakawa, et al.
    • Organizer
      The 9th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji Yumebutai International Conference Center
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] 細菌エフェクターOspEとインテグリンリンクドキナーゼの結合による感染細胞の剥離抑制機構2009

    • Author(s)
      Minsoo Kim, 笹川千尋
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Autophagy Evasion by Cytosolic Bacteria.2009

    • Author(s)
      Sasakawa, C.
    • Organizer
      109^<th> General Meeting of the American Society for Microbiology
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Control of Gastric Epithelial Cell by Helicobacter pylori infection2009

    • Author(s)
      Hitomi Mimuro, Chihiro Sasakawa
    • Organizer
      109th General Meeting of the American Society for Microbiology
    • Place of Presentation
      Philadelphia, U.S.A
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Autophagy Evasion by Cytosolic Bacteria.2009

    • Author(s)
      Chihiro Sasakawa
    • Organizer
      109th General Meeting of the American Society for Microbiology
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Shigella Exploitation and Subversion of Host Cell Function2009

    • Author(s)
      Chihiro Sasakawa
    • Organizer
      The 9th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji Yumebutai International Conference Center
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] 細菌エフェクターOspEとインテグリンリンクドキナーゼの結合による感染細胞の剥離抑制機構2009

    • Author(s)
      Minsoo Kim, 笹川千尋
    • Organizer
      第32回 日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella infection of intestinal mucosa and host response2008

    • Author(s)
      Sasakawa C.
    • Organizer
      The 9^<th> Korea-Japan International Symposium on Microbiology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-10-17
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] 赤痢菌の腸上皮バリアーへの感染戦略2008

    • Author(s)
      笹川千尋
    • Organizer
      JCS2008-Joint Conference in Sapporo 2008-
    • Place of Presentation
      北海道大学学術交流会館
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella modulerar immunsvaret.2008

    • Author(s)
      Sasakawa, C.
    • Organizer
      Swedish Microbiologist Meeting
    • Place of Presentation
      Umea, Sweden
    • Year and Date
      2008-06-04
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella intracellular survival strategy2008

    • Author(s)
      Sasakawa, C.
    • Organizer
      The 65th KSBMB Annual Meeting in 2008 & KSMBMB-KSBMB Joint Symposium
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-05-05
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Bacterial Exploitation and Subversion of Host Cell Function During Infection : in the case of Shigella2008

    • Author(s)
      Sasakawa, C.
    • Organizer
      1st China-Japan Joint Workshop on New-Generatio n Vaccines for Infectious Diseases
    • Place of Presentation
      Beijing, China
    • Year and Date
      2008-05-22
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella infection of intestinal mucosa and host response.2008

    • Author(s)
      Sasakawa, C.
    • Organizer
      The 9^<th> Korea-Japan International Symposium on Microbiology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-10-17
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella modulerar immunsvaret2008

    • Author(s)
      Sasakawa C.
    • Organizer
      Swedish Microbiologist Meeting
    • Place of Presentation
      Umea, Sweden
    • Year and Date
      2008-06-04
    • Data Source
      KAKENHI-PROJECT-20229006
  • [Presentation] Shigella infection of intestinal mucosa and host response2008

    • Author(s)
      Sasakawa, C.
    • Organizer
      The 9th Korea-Japan International Symposium on Microbiology 2008
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-10-16
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella modulerar immunsvaret2008

    • Author(s)
      Sasakawa, C.
    • Organizer
      Swedish Microbiologist Meeting
    • Place of Presentation
      Umea, Sweden
    • Year and Date
      2008-06-04
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] 赤痢菌の腸粘膜バリアーへの感染戦略2008

    • Author(s)
      笹川千尋
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド神戸
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] 削化管粘膜における赤痢菌の感染戦略2007

    • Author(s)
      笹川千尋
    • Organizer
      第27回日本医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-04-04
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella Infection Maneuver.2007

    • Author(s)
      Sasakawa, C.
    • Organizer
      MBO-FEMS-LEOLOLDINA Symposium
    • Place of Presentation
      Kloster Banz, Germany
    • Year and Date
      2007-10-12
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella Infection Maneuve2007

    • Author(s)
      Sasakawa, C.
    • Organizer
      EMBO-FEMS-LEOLOLDINA Symposium
    • Place of Presentation
      Kloster Banz, Germany
    • Year and Date
      2007-10-12
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] A combat between Shigella and host in GI tract2007

    • Author(s)
      Sasakawa C.
    • Organizer
      13th International Congress of Mucosal Immunology
    • Place of Presentation
      Shinagawa, Japan
    • Year and Date
      2007-07-11
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] Shigella intracellular survival strategy.2006

    • Author(s)
      Sasakawa, C.
    • Organizer
      Interface of Cell Biology and Cellular Microbiology of European Science Foundation Meeting 2006
    • Place of Presentation
      San Felie de Guixols, Spain
    • Data Source
      KAKENHI-PLANNED-18073003
  • [Presentation] 腸粘膜における赤痢菌と自然免疫の攻防

    • Author(s)
      笹川千尋
    • Organizer
      第155回日本獣医学会学術集会
    • Place of Presentation
      東京大学駒場キャンパス(東京都)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin to activate inflammasomes

    • Author(s)
      鈴木志穂, 三室仁美, 小川道永, 芦田浩, 鈴木仁人, 真田貴人, 笹川千尋
    • Organizer
      第88回日本細菌学会総会
    • Place of Presentation
      長良川国際会議場(岐阜県岐阜市)
    • Year and Date
      2015-03-27 – 2015-03-28
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] Shigella Type III Secretion Protein MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation

    • Author(s)
      Shiho Suzuki, Luigi Franchi, Yuan He, Hitomi Mimuro, Chihiro Sasakawa, Gabriel Núñez
    • Organizer
      The 13th Awaji International Forum on Infection and Immunity in Nara
    • Place of Presentation
      奈良県新公会堂(奈良県奈良市)
    • Year and Date
      2014-09-23 – 2014-09-26
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-23000012
  • [Presentation] A New Paradigm of Bacterial-Gut Interplay Brought Through the Study of Shigella

    • Author(s)
      Chihiro Sasakawa
    • Organizer
      Doug's symposium
    • Place of Presentation
      St.Louis (United States of America)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23000012
  • 1.  YOSHIKAWA Masanosuke (80012714)
    # of Collaborated Projects: 5 results
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  • 2.  KITA Kiyoshi (90134444)
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  • 3.  TOBE Toru (70207596)
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  • 4.  OKADA Nobuhiko (80194364)
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  • 5.  MITSUYAMA Masao (10117260)
    # of Collaborated Projects: 4 results
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  • 6.  KOYANAGI Yoshio (80215417)
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  • 7.  DANBARA Hirobumi (40114558)
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  • 8.  MAKINO Sou-ichi (30181621)
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  • 9.  NOMOTO Akio (70112670)
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  • 10.  YANAGI Yusuke (40182365)
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  • 11.  TERAWAKI Yoshiro (10014333)
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  • 12.  本田 武司 (60029808)
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  • 13.  中村 信一 (90019620)
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  • 14.  審良 静男 (50192919)
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  • 15.  OGUMA Keiji (00002262)
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  • 16.  NISHIYAMA Yukihiro (60115615)
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  • 17.  KAWABATA Shigetada (50273694)
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  • 18.  FUKUDA Ichiro (10242108)
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  • 19.  NAKAZAWA Teruko (40053053)
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  • 20.  EZAKI Takayuki (90151977)
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  • 23.  IIDA Tetsuya (90221746)
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  • 24.  FUJITA Takashi (10156870)
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  • 25.  HORIGUCHI Yasuhiko (00183939)
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  • 26.  KOYASU Shigeo (90153684)
    # of Collaborated Projects: 1 results
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  • 27.  HORII Toshihiro (80142305)
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  • 28.  NOZAKI Tomoyoshi (60198588)
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  • 29.  NAKANISHI Kenji (60172350)
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  • 30.  IKE Yasuyoshi (60125820)
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  • 31.  ONISHI Yoshinari (10037400)
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  • 32.  AMAKO Kazunobu (20078752)
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  • 33.  NARIUCHI Hideo (10012741)
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  • 34.  SHIMADA Hiroyuki (60113487)
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  • 37.  OKADA Yumiko (50232137)
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  • 38.  HAYASHI Hideo (40033203)
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  • 39.  IMAJOH-OHMI Shinobu (20160046)
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  • 40.  YAMAMOTO Tatsuo (80095843)
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  • 41.  MIYATA Makoto (50209912)
    # of Collaborated Projects: 1 results
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  • 42.  MORI Hiroyuki (10243271)
    # of Collaborated Projects: 1 results
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  • 43.  UYEDA Q. Taro (90356551)
    # of Collaborated Projects: 1 results
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  • 44.  KOJIMA Seiji (70420362)
    # of Collaborated Projects: 1 results
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  • 45.  KATAYAMA Eisaku (50111505)
    # of Collaborated Projects: 1 results
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  • 46.  KODERA Noriyuki (30584635)
    # of Collaborated Projects: 1 results
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  • 47.  TAOKA Azuma (20401888)
    # of Collaborated Projects: 1 results
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  • 48.  KAWAKAMI Masaru (70452117)
    # of Collaborated Projects: 1 results
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  • 49.  KOUYAMA Tsutomu (30170210)
    # of Collaborated Projects: 1 results
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  • 50.  ISHIWATA Shin'ichi (10130866)
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  • 51.  NAMBA Kiichi (30346142)
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  • 52.  伊藤 喜久治 (50100045)
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  • 53.  伊藤 豊志雄 (20106644)
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  • 55.  白幡 敏一 (90003110)
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  • 56.  野田 公俊 (60164703)
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  • 57.  井上 公蔵 (10028300)
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  • 58.  西渕 光昭 (50189304)
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  • 61.  橋本 一 (90008235)
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  • 62.  吉村 文信 (50001962)
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  • 63.  本間 道夫 (50209342)
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  • 64.  加藤 貴之 (20423155)
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  • 65.  伊藤 政博 (80297738)
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  • 66.  中山 浩次 (80150473)
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  • 67.  西坂 崇之 (40359112)
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  • 68.  福森 義宏 (60135655)
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  • 69.  TOYOSHIMA Kumao
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  • 70.  SASAZUKI Takehiko
    # of Collaborated Projects: 1 results
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  • 71.  NAGAI Yoshiyuki
    # of Collaborated Projects: 1 results
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  • 72.  NAGATA Kyosuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 73.  IWAMOTO Aikichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 74.  KAWAOKA Yoshihiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 75.  NONAKA Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 76.  KIM Minsoo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 77.  ASHIDA Hiroshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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