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Tone Shigenobu  刀袮 重信

ORCIDConnect your ORCID iD *help
… Alternative Names

刀袮 重信  トネ シゲノブ

Shigenobu Tone  刀祢 重信

TONE Shigenobu  刀祢 重信

刀根 重信  トネ シゲノブ

TONE Sigenobu  刀禰 重信

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Researcher Number 70211399
Other IDs
External Links
Affiliation (Current) 2025: 東京電機大学, 理工学部, 研究員
Affiliation (based on the past Project Information) *help 2016 – 2023: 東京電機大学, 理工学研究科, 特別専任教授
2016: 東京電機大学, 理工学部生命理工学系分子発生生物学研究室, 教授
2015: 川崎医科大学, 医学部, 准教授
2008 – 2013: Kawasaki Medical School, 医学部, 准教授
1998 – 2005: 川崎医科大学, 医学部, 助教授 … More
1998: Kawasaki Medical School associate, professor, 医学, 助教授
1996: (財)東京都臨床医学研究所, 放射線医学, 研究員
1996: The Tokyo Metropolitan Institute of Medical Science, Dept.of Radiation Research,, 放射線医学研究部門, 研究員
1996: 東京都臨床医学総合研究所放射線医学研究部門, 主任研究員
1996: 財団法人 東京都臨床医学総合研究所, 放射線医学研究部門, 研究員
1995: The Tokyo Metropolitan Institute for Medical Science Department of Radiation Bio, 放射線医学部門・総合研究所, 研究員
1995: (財)東京都臨床医学総合研究所, 放射線医学部門, 研究員
1995: Tokyo Metropolitan Instittute for Clinical Medicine, Dept.of Radiological Medici, 放射線医学研究部門, 主任研究員
1995: 東京都臨床医学総合研究所, 放射線医学研究部門, 主任研究員
1995: Tokyo Metropolitan Clinical Research Institute, Dept.of Radiology, Chief Invesat, 放射線医学部門, 主任研究員
1994: 和歌山県立医大, 助手
1991 – 1994: 和歌山県立医科大学, 医学部, 助手
1993: 和歌山医科大学, 助手
1993: Wakayama Prefectural University of Medicine Biochemistry Research associate, 助手
1992: 和歌山医大, 助手 Less
Review Section/Research Field
Principal Investigator
Morphology/Structure / General anatomy (including Histology/Embryology) / Experimental pathology
Except Principal Investigator
Nerve anatomy/Neuropathology / Obstetrics and gynecology / Biological Sciences / General medical chemistry / Basic Section 56020:Orthopedics-related / Basic Section 80040:Quantum beam science-related / Quantum beam science … More / Cardiovascular medicine / Pediatric surgery / General anatomy (including Histology/Embryology) / 生物形態・構造 / Legal medicine / Functional biochemistry / 代謝生物化学 / 動物発生・生理学 / Basic veterinary science/Basic zootechnical science / General surgery / Obstetrics and gynecology / Cell biology Less
Keywords
Principal Investigator
核 / アポトーシス / リモデリング / ヒストン / 国際情報交換 / DNase / アクチン / キナーゼ / 凝縮 / 分子形態学 … More / 幹細胞 / メチル化 / 細胞融合 / 細胞工学 / 再生 / FS細胞 / 臓器移植 / 核移植 / ES細胞 … More
Except Principal Investigator
アポトーシス / インドールアミン酸素添加酵素 / トリプトファン代謝 / c-fos / ラット / 細胞死 / 分子生物学 / IDO / トリプトファン / IFN-γ / リン酸基 / 軟X線顕微鏡 / p53 / apoptosis / tryptophan metabolism / IRF-1 / pseudorabies virus / 細胞内情報伝達機構 / 転写制御因子 / Northern hybridization / Protamine / cDNA / Hormones / Culture / Spermatogenesis / Medaka / 胎児-母体間免疫 / 生殖医学 / 変性 / 神経突起 / 胎盤 / 酸素添加酵素 / 免疫寛容 / ノックアウトマウス / 誘導酵素 / 形態形成 / 無精子症 / 脊椎損傷 / 造精機能障害 / 脊髄損傷 / 男性不妊症 / ナノ / 高空間分解能 / 電子構造 / コンフォメーション / 吸収端構造 / 超解像 / STED / シンチレーター / 誘導放出抑制 / 軟X線 / レーザー生成プラズマ光源 / 軟Ⅹ線顕微鏡 / 量子ビーム / Ⅹ線 / レーザー励起プラズマ光源 / 軟X線顕微鏡 / LPP光源 / P-L2,3吸収端 / ヌクレオチド / レーザープラズマ光源 / 反射多層膜 / UTA放射 / 水の窓 / 血管内皮機能障害 / 脳卒中 / 脈波伝播速度 / 脈波 / バイオマーカー / 脳梗塞 / 脳小血管病 / short bowel syndrome / activin A / gut / smooth muscle / tissue engineering / iPS cell / 人工腸管 / 胚様体 / iPS細胞 / 腸管分化誘導 / 再生医療 / quinolinic acid / post-translational modification / excitatory neurotoxin / INF-γ / knockout mouse / Alzheimer's disease / Kynurenylation / 翻訳後蛋白修飾 / 感染防御機構 / 翻訳語蛋白修飾 / 興奮性神経毒 / インターフェロンガンマ / アルツハイマー病 / キヌレニン化 / functional domain / nuclear translocation / anchoring function / vimentin / cytoskeleton / 核移行反応 / 機能ドメイン解析 / 核内移行反応 / アンカー機能 / ビメンチン / 細胞骨格 / DNA fragmentation / gene / limb-bud / 胚芽 / DNA切断 / 遺伝子 / 肢芽 / TNF alpha / Necrosis / Apoptosis / Cell Death / Injury / 細胞死機構 / TNF-α / TNF-2 / ネクローシス / 損傷 / ISRE / cytokine / transcriptional factor / indoleamine 2,3-dioxygenase / interferon-gamma / STAT 1 / STAT1 / 酵素誘導 / Cornea / Heart / Stress / Brain / Rat / NGFI-A (zif268) / Proto-oncogenes / 視床下部室傍核 / NGFI-A / 角膜 / 心臓 / ストレス / 脳 / NGFI‐A(zif268) / c‐fos / 細胞性癌遺伝子 / retrograde transport / mesencephalic trigeminal nucleus / motor trigeminal nucleus / masseter / gene-delivery / transneuronal tracer / ペプチド / pseudorabies / ウイルス / neuron / Transneuronal tracer / Pseudorabies virus / 後根神経節 / トレーサー / 神経細胞 / トランスフェクション / 逆行性輸送 / 三叉神経中脳路核 / 三叉神経運動核 / 咬筋 / 遺伝子導入 / トランスニューロナル・トレーサー / 偽狂犬病ウィルス / Tryptophan metabolism / Cytokine / Signal transduction / Trans-acting factor / Interferon-gamma / Oxygenase / 細胞内情報伝達 / インターフェロンーγ / インターフェロン-γ / サイトカイン / Arginnine / 免疫組織化学 / BrdU / 機能的精子分化 / 精巣断片 / 精母細胞 / 遺伝子解析 / 抗プロタミン抗体 / ホルモン / ノーザンハイブリダイゼーション / mRNA / プロタミン遺伝子 / プロタミン / 培養 / 精子形成 / メダカ / Arginine / タンパク質高次構造 / レポーターアッセイ / ケミカルライブラリー / 抗がん剤 / タンパク質高次構造変化 / 細胞増殖 / ガン細胞 / Western blot法 / プロスタグランジン / 絨毛膜羊膜炎(CAM) / 早産 / indoleamine 2,3-dioxygnase / 絨毛膜羊膜炎 / 必須アミノ酸 / NF-kBシグナリング / 免疫調節因子 / 転写調節因子 / インドール環 / 構造活性相関 / 静電ポテンシャル / トリプトファン誘導体 / インドールアミン酸素添加素 / 核移植 / サイトプラスト / 細胞脱核法 / 細胞融合 / ES細胞 / ワーラー変性 / コルヒチン / ネクローンス / 脱分極 / レドックス制御 / Ca^<2+>チャネル / 顆粒細胞 / カスパーゼ / 母体 / 妊娠 / 胎児 / TDO / 抗細胞内寄生虫活性 / Zif268 / 直早期遺伝子 / 暗所飼育 / 大脳皮質視覚野 / 発達 / 視覚野 / 視覚遮断 / amblyopia / 免疫不全 / 免疫レパートリ形成 / 細胞交替 / 奇形 / 生理的細胞死 / プログラム細胞死 Less
  • Research Projects

    (28 results)
  • Research Products

    (60 results)
  • Co-Researchers

    (56 People)
  •  Development of a new treatment for the patients with spinal injury accompanied by defective spermatogenesis

    • Principal Investigator
      原 綾英
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kawasaki Medical School
  •  Spectral Changes of Phosphorus Absorption Edge by Changing Phosphate Molecules and its Application to Chromatin Visualization

    • Principal Investigator
      EJIMA TAKEO
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 80040:Quantum beam science-related
    • Research Institution
      Tohoku University
  •  Development of soft X-ray microscope in Water window wavelength region using Flash LPP light source

    • Principal Investigator
      Ejima Takeo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Quantum beam science
    • Research Institution
      Tohoku University
  •  New approach to treat stroke by assessing cerebral small vessel dysfunction indicated by pulse wave velocity and biomarkers

    • Principal Investigator
      SAJI Naoki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      National Center for Geriatrics and Gerontology
      Kawasaki Medical School
  •  Initinal research for tissue engineering intestine using iPS cells

    • Principal Investigator
      Yoshida Atsushi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatric surgery
    • Research Institution
      Kawasaki Medical School
  •  Genome-wide analysis of nuclear condensation factors during apoptosisPrincipal Investigator

    • Principal Investigator
      TONE Shigenobu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphology/Structure
    • Research Institution
      Kawasaki Medical School
  •  Fundamental studies for development of a novel anti-tumor drug based on perchloric acid-soluble protein

    • Principal Investigator
      KANOUCHI HIROAKI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Kagoshima University
  •  Role of tryptophan analogue and clarification of its action mechanism in the immunity between embryo-mother's bodies

    • Principal Investigator
      OKAMOTO Takeaki
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Ehime University
      Kawasaki Medical School
  •  Molecular Cell Biological Analysis of Nuclear Condensation in ApoptosisPrincipal Investigator

    • Principal Investigator
      TONE Shigenobu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Kawasaki Medical School
  •  Role of tryptophan and clarification of its action mechanism in the immunity between embryo-mother's bodies

    • Principal Investigator
      OKAMOTO Takeaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kawasaki Medical School
  •  体細胞を脱核幹細胞と融合して幹細胞化する試み

    • Principal Investigator
      四宮 貴久
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      National Research Institute for Child Health and Development
  •  Generation of indoleamine 2,3-dioxygenase-dificient mouse

    • Principal Investigator
      TAKIKAWA Osamu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  神経突起変性により誘導されるカスケードとその神経変性疾患モデルにおける解析

    • Principal Investigator
      小池 達郎
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  神経突起変性により誘発される細胞内カスケードの解明

    • Principal Investigator
      小池 達郎
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  胚性幹細胞に体細胞の核を移植する試み-臓器移植をめざした基礎的研究-Principal Investigator

    • Principal Investigator
      刀袮 重信 (刀祢 重信)
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Kawasaki Medical School
  •  胎盤でのトリプトファン酸素添加酵素阻害は果して流産の原因となるか?

    • Principal Investigator
      河野 一郎
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kawasaki Medical School
  •  NUCLEAR PROTEIN-ANCHORING FUNCTION OF CYTOSKELETON AND ITS ANTI-APOPTOTIC EFFECTS AGAINST P53-DEPENDENT APOPTOSIS.

    • Principal Investigator
      NISHIO Koji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      NAGOYA UNIVERSITY
  •  幼若ラット視覚野の回路発達に関する遺伝子群の検索とその役割の検討

    • Principal Investigator
      仙波 恵美子
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Wakayama Medical University
  •  IFN−γで誘導されるトリプトファン分解酵素のノックアウトマウスの作製

    • Principal Investigator
      TAKIKAWA Osamu
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka Bioscience Institute
  •  Molecular mechanism of programmed cell death.Principal Investigator

    • Principal Investigator
      KURIHARA Keiko, 刀祢 重信
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      生物形態・構造
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  光刺激による幼若ラット視覚野の回路発達に関する遺伝子群の検索

    • Principal Investigator
      SENBA Emiko
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Wakayama Medical University
  •  Cell-Biological Study on Medicolegal Diagnosis of Injury

    • Principal Investigator
      TSUJI Tsutomu
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      Wakayama Medical College
  •  The roles and regulatory mechanisms of expression of proto-oncogenes in the nervous system

    • Principal Investigator
      SENBA Emiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Wakayama Medical College
  •  Molecular cloning of cDNAs for transcriptional factors of indoleamine 2,3-dioxygenase induced by IFN-gamma

    • Principal Investigator
      TAKIKAWA Osamu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Osaka Bioscience Institute
  •  アポトーシスの機能と分子機構

    • Principal Investigator
      山田 武
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Toho University
  •  The development of viral vector for in vivo gene-delivery and its applications

    • Principal Investigator
      SENBA Emiko, 野口 光一
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Wakayama Medical College
  •  Molecular cloning of trans-acting factor cDNA for IFN-gamma-inducible indoleamine 2,3-dioxygenase

    • Principal Investigator
      TAKIKAWA Osamu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      Osaka Bioscience Institute
  •  In vitro analysis of spermatogenesis in the medaka, Oryzias latipes.

    • Principal Investigator
      ONITAKE Kazuo
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      動物発生・生理学
    • Research Institution
      Yamagata University

All 2020 2019 2018 2017 2016 2014 2013 2012 2011 2010 2009 2007 Other

All Journal Article Presentation Book

  • [Book] 細胞死実験プロトコル2011

    • Author(s)
      刀祢重信, (編集及び共著)
    • Total Pages
      223
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Book] 細胞死解析プロトコル2011

    • Author(s)
      刀祢重信
    • Total Pages
      224
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Book] Methods in Molecular Biology : imaging of mitotic cell division and apoptotic intra-nuclear processes in multicolor2009

    • Author(s)
      Sugimoto K, Tone S. (in press)
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Book] Induction of indoleamine2,3-dioxygenase in small intestine of ,mouse infected with parasitic helminth, hymenolepis nana2007

    • Author(s)
      Fumio Ohyama, Shigenobu Tone, Takeaki Okamotoほか2名
    • Publisher
      The interdisciplinary conference on tryptophan
    • Data Source
      KAKENHI-PROJECT-19791177
  • [Book] Down-regulation of the indoleamine 2,3-dioxygenase (IDO) transcription by tryptophan analogue2007

    • Author(s)
      Takeaki Okamoto, Sigenobu Tone,Hiroaki Kanouchi,Fumio Ohyama,Yohsuke Minatogawa
    • Publisher
      The interdisciplinary conference on tryptophan
    • Data Source
      KAKENHI-PROJECT-19791177
  • [Journal Article] Nutritional exchange of old and new body of just rejuvenated individual of Turritopsis sp. (Hydrozoa, Anthomedusae) from Wakayama Prefecture, Japan2020

    • Author(s)
      久保田信 刀祢重信
    • Journal Title

      Bull. biogeogr. Soc. Japan

      Volume: 75 Pages: 140142-140142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H04391
  • [Journal Article] A low amyloidogenic E61K transthyretin mutation may cause familial amyloid polyneuropathy.2020

    • Author(s)
      Murakami T, Yokoyama T, Mizuguchi M, Ton&#233; S, Takaku S, Sango K, Nishimura H, Watabe K, Sunada Y.
    • Journal Title

      J Neurochem

      Volume: 156 Issue: 6 Pages: 957-966

    • DOI

      10.1111/jnc.15162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06507, KAKENHI-PROJECT-19H04391, KAKENHI-PROJECT-20K07773
  • [Journal Article] Quantitative Distribution of DNA, RNA, Histone and Proteins Other than Histone in Mammalian Cells, Nuclei and a Chromosome at High Resolution Observed by Scanning Transmission Soft X-Ray Microscopy (STXM)2019

    • Author(s)
      K. Shinohara, S. Tone, T. Ejima, T. Ohigashi, A. Ito
    • Journal Title

      Cells

      Volume: 8 Issue: 2 Pages: 164-164

    • DOI

      10.3390/cells8020164

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K05000, KAKENHI-PROJECT-16H03902, KAKENHI-PROJECT-16K05021, KAKENHI-PROJECT-16K05022, KAKENHI-PROJECT-17H03013, KAKENHI-PROJECT-19H04391, KAKENHI-PROJECT-17K19021
  • [Journal Article] hemical Bonding State Change of Phosphodiester Bonds in Plasmid DNA2018

    • Author(s)
      T. Ejima, T. Ohigashi, M. Kado, and S. Tone
    • Journal Title

      UVSOR Activity Report

      Volume: 2017 Pages: 157-157

    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Journal Article] Discrimination of DNA and RNA distribution in a mammalian cell by scanning transmission soft X-ray microscopy2018

    • Author(s)
      Shinohara Kunio、Ito Atsushi、Ohigashi Takuji、Kado Masataka、Tone Shigenobu
    • Journal Title

      Journal of X-Ray Science and Technology

      Volume: 26 Issue: 6 Pages: 877-884

    • DOI

      10.3233/xst-180392

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H03902, KAKENHI-PROJECT-16K05021, KAKENHI-PROJECT-16K05022
  • [Journal Article] Cilostazol May Decrease Plasma Inflammatory Biomarkers in Patients with Recent Small Subcortical Infarcts: A Pilot Study.2018

    • Author(s)
      Saji N, Tone S, Murotani K, Yagita Y, Kimura K, Sakurai T.
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: S1052-3057 Issue: 6 Pages: 30036-3

    • DOI

      10.1016/j.jstrokecerebrovasdis.2018.01.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Journal Article] Analysis of Apoptotic Nuclei with Infrared Spectra-Microscopy2018

    • Author(s)
      M. Kado, T. Ejima, T. Tone, K. Shinohara
    • Journal Title

      SPring-8/SACLA Research Report

      Volume: 6 Issue: 1 Pages: 35-37

    • DOI

      10.18957/rr.6.1.35

    • NAID

      130007969489

    • ISSN
      2187-6886
    • Year and Date
      2018-01-25
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19021, KAKENHI-PROJECT-16H03902
  • [Journal Article] 人工海水の止水飼育下でのベニクラゲの若返り, クラゲ芽形成, 並びに第2回目の若返りの初記録2018

    • Author(s)
      大塚玲桜, 藤瀬弦汰, 久保田信, 刀祢重信
    • Journal Title

      日本生物地理学会会報

      Volume: 73 Pages: 1901-94

    • NAID

      40021767302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Journal Article] Development of laboratory-type soft X-ray microscope, CXRM, in Water-window using LPP light source2018

    • Author(s)
      Ejima Takeo、Ono Yuichi、Ito Keisuke、Kawasaki Hiromu、Higashiguchi Takeshi、Tone Shigenobu、Hatano Tadashi
    • Journal Title

      Microscopy and Microanalysis

      Volume: 24 Issue: S2 Pages: 214-215

    • DOI

      10.1017/s1431927618013417

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19021, KAKENHI-PROJECT-16H03902
  • [Journal Article] Quantitative analysis of mammalian chromosome by scanning transmission soft X-ray microscopy2018

    • Author(s)
      K. Shinohara, T. Ohigashi, S. Tone, M. Kado, A. Ito
    • Journal Title

      Ultramicroscopy,

      Volume: 194 Pages: 1-6

    • DOI

      10.1016/j.ultramic.2018.07.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K05000, KAKENHI-PROJECT-16H03902, KAKENHI-PROJECT-17H03013, KAKENHI-PROJECT-16K05021
  • [Journal Article] Intracellular morphological changes in Staphylococcus aureus induced by treatment with sodium hypochlorite2017

    • Author(s)
      Ujimine S, Tone S, Saito M, Yamada S.
    • Journal Title

      Med Mol Morphol.

      Volume: 50 Issue: 3 Pages: 178-184

    • DOI

      10.1007/s00795-017-0159-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Journal Article] Distribution of DNA and Protein in Mammalian Cell Nuclei calculated using NEXAFS profiles at the N-K and O-K edges2016

    • Author(s)
      A. Ito, T. Ohigashi, K. Shinohara, S. Tone, M. Kado, Y. Inagaki and N. Kosugi
    • Journal Title

      UVSOR Activity Report

      Volume: 2015 Pages: 143-143

    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Journal Article] Role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in patients with recurrent miscarriag2016

    • Author(s)
      Yuki Obayashi, Yasuhiko Ozaki, Satomi Kurakane, Shinobu Goto, Kyoko Kumagai, Tamao Kitaori, Suzumori Nobuhiro, Mayumi Sugiura
    • Journal Title

      American Journal of Reproductive Immunology

      Volume: 75 Issue: 1 Pages: 69-77

    • DOI

      10.1111/aji.12434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20154, KAKENHI-PROJECT-24592478, KAKENHI-PROJECT-25462571, KAKENHI-PROJECT-16K11100, KAKENHI-PROJECT-16H03902
  • [Journal Article] Novel and Robust Transplantation Reveals the Acquisition of Polarized Processes by Cortical Cells Derived from Mouse and Human Pluripotent Stem Cells2014

    • Author(s)
      Nagashima F, Suzuki IK, Shitamukai A, Sakaguchi H, Iwashita M, Kobayashi T, Tone S, Toida K, Vanderhaeghen P, Kosodo Y.
    • Journal Title

      Stem Cells Dev.

      Volume: E-Pub

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Journal Article] Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival2013

    • Author(s)
      Rezano A, Kuwahara K, Yamamoto-Ibusuki M, Kitabatake M, Moolthiya P, Phimsen S, Suda T, Tone S, Yamamoto Y, Iwase H, Sakaguchi N
    • Journal Title

      BMC Cancer

      Volume: 13 Issue: 1 Pages: 562-562

    • DOI

      10.1186/1471-2407-13-562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23570083, KAKENHI-PROJECT-24590388, KAKENHI-PROJECT-24659224, KAKENHI-PROJECT-25860813
  • [Journal Article] A Novel Mutation of Human Liver Alanine:Glyoxylate Aminotransferase Causes Primary Hyperoxaluria Type 1 -Immunological quantification and subcellular distribution-2012

    • Author(s)
      Kawai C, Minatogawa Y, Akiyoshi H, Hirose S, Suehiro T, Tone S
    • Journal Title

      Acta Histochemica et Cytochemica

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Journal Article] The actin family member Arp6 and the histone variant H2A.Z are required for spatial positioning of chromatin in chicken cell nuclei.2012

    • Author(s)
      Maruyama EO, Hori T, Tanabe H, Kitamura H, Matsuda R, Tone S, Hozak P, Habermann FA, von Hase J, Cremer C, Fukagawa T, Harata M
    • Journal Title

      J Cell Sci.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Journal Article] Selective cell death of p53-insufficient cancer cells is induced by knockdown of the mRNA export molecule GANP2012

    • Author(s)
      Phimsen S, et al
    • Journal Title

      Apoptosis

      Volume: (印刷中) Issue: 7 Pages: 679-690

    • DOI

      10.1007/s10495-012-0711-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22021036, KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23570083, KAKENHI-PROJECT-23791116, KAKENHI-PROJECT-24590388
  • [Journal Article] The actin family member Arp6 and the histone variant H2A.Z are required for spatial positioning of chromatin in chicken cell nuclei.2012

    • Author(s)
      Maruyama E., Hori T., Tanabe H., Kitamura H., Matsuda R., Tone S., Pavel H., Habermann FA., Hase JV, Cremer C., Fukagawa T, and Harata(equal first authors)
    • Journal Title

      Journal of Cell Science

      Volume: 125 Pages: 3739-3743

    • DOI

      10.1242/jcs.103903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J05962, KAKENHI-PROJECT-22570008, KAKENHI-PROJECT-23570083, KAKENHI-PROJECT-23658281, KAKENHI-PROJECT-23810015, KAKENHI-PROJECT-24380183, KAKENHI-PUBLICLY-23114702, KAKENHI-PUBLICLY-23114722, KAKENHI-PUBLICLY-23125505
  • [Journal Article] Selective cell death of p53-insufficient cancer cells is induced by knockdown of the mRNA export molecule GANP.2012

    • Author(s)
      Phimsen S, Kuwahara K, Nakaya T, Ohta K, Suda T, Rezano A, Kitabatake M, Vaeteewoottacharn K, Okada S, Tone S, Sakaguchi N.
    • Journal Title

      Apoptosis

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Journal Article] A Novel Mutation of Human Liver Alanine:Glyoxylate Aminotransferase Causes Primary Hyperoxaluria Type 1: Immunohistochemical Quantification and Subcellular Distribution2012

    • Author(s)
      Kawai C, Minatogawa Y, Akiyoshi H, Hirose S, Suehiro T, Tone S
    • Journal Title

      ACTA HISTOCHEMICA ET CYTOCHEMICA

      Volume: 45 Issue: 2 Pages: 121-129

    • DOI

      10.1267/ahc.11042

    • NAID

      130001854237

    • ISSN
      0044-5991, 1347-5800
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249062, KAKENHI-PROJECT-23570083, KAKENHI-PROJECT-23659529
  • [Journal Article] Clostridium perfringens iota-b induces rapid cell necrosis2011

    • Author(s)
      Masahiro Nagahama
    • Journal Title

      Infect.Immun.

      Volume: 79 Issue: 11 Pages: 4353-4360

    • DOI

      10.1128/iai.05677-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590500, KAKENHI-PROJECT-23570083
  • [Journal Article] Possible involvement of caspase-6 and -7 but not caspase-3 in the regulation of hypoxia-induced apoptosis in tube-forming endothelial cells.2009

    • Author(s)
      Eguchi R, Tone S, et al
    • Journal Title

      Exp.Cell Res 315

      Pages: 327-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Journal Article] Imaging of mitotic cell division and apoptotic intra-nuclear processes in multicolor.2009

    • Author(s)
      Sugimoto K, Tone S
    • Journal Title

      Methods in Molecular Biology 591

      Pages: 135-146

    • Data Source
      KAKENHI-PROJECT-20590203
  • [Journal Article] Transcriptional regulation of indoleamine 2,3-dioxygenase (IDO) by tryptophan and its analogue2007

    • Author(s)
      Takeaki Okamoto, Shigenobu Tone, Hiroaki Kanouchi, Chie Miyawaki, Sayuri Ono, Yohsuke Minatogawa
    • Journal Title

      Cytotechnology 54

      Pages: 107-113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791177
  • [Presentation] Analysis of apoptosis induced by actin C-terminal 15 kDa fragment2018

    • Author(s)
      Kamiyama H, Ito N, Tone S, Tanaka M
    • Organizer
      American Society of Cell Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Presentation] BiターゲットLPP光源を用いた軟X線顕微鏡CXRM2018

    • Author(s)
      江島丈雄、小野祐一、伊藤圭祐、川崎大夢、羽多野忠、刀祢重信、東口武史
    • Organizer
      第79回応用物理学会秋季学術講演会
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Presentation] Development of laboratory-type soft X-ray microscope, CXRM, in Water-window using LPP light source2018

    • Author(s)
      Takeo Ejima, Yuichi Ono, Keisuke Ito, Hiromu Kawasaki, Takeshi Higashiguchi, Shigenobu Tone and Tadashi Hatano
    • Organizer
      14th International conference on x-ray microscopy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Presentation] βアクチンのC末端側断片は細胞死を誘起する2017

    • Author(s)
      伊東奈那子、刀祢重信、田中眞人
    • Organizer
      第26回日本Cell Death 学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Presentation] プロフィリンはβ-アクチンの15kDa-C末端側断片が引き起こす細胞死を抑制する2017

    • Author(s)
      伊東奈那子、本多弘幸、刀祢重信、田中眞人
    • Organizer
      第26回日本Cell Death 学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Presentation] アポトーシス研究におけるエレクトロポレーション法の優位性について2017

    • Author(s)
      刀祢重信
    • Organizer
      第122回日本解剖学会
    • Place of Presentation
      長崎大学、長崎県長崎市
    • Year and Date
      2017-03-30
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Presentation] C-terminal 15kDa fragment from β-actin causes apoptotic cell death.2017

    • Author(s)
      Ito, N., Tone, S. and Tanaka, M.
    • Organizer
      Annual Meeting 2017 of American Society for Biochemistry and Molecular Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Presentation] QUANTITATIVE STUDY OF MAMMALIAN CELLS BY SCANNING TRANSMISSION SOFT X-RAY MICROSCOPY2016

    • Author(s)
      篠原邦夫, 大東琢治, 刀祢重信, 加道雅孝, 伊藤敦
    • Organizer
      X-Ray Microscopy Conference 2016
    • Place of Presentation
      Oxford University, UK
    • Year and Date
      2016-08-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Presentation] Profilins suppress the apoptosis induced by cytoskeletal 15kDa-β-actin in cancer cell lines2016

    • Author(s)
      N. Ito, H. Honda, S. Tone, M. Tanaka
    • Organizer
      The American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Moscone Center, San Francisco, US
    • Year and Date
      2016-12-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03902
  • [Presentation] アポトーシスに見る自己集合現象ワークショップ「生命における自己組織化のメカニズム」2013

    • Author(s)
      刀祢重信
    • Organizer
      第36回分子生物学会年会
    • Place of Presentation
      神戸市
    • Year and Date
      2013-12-06
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] アポトーシスにおける核凝縮の3つの素過程リング、ネックレス、核崩壊をそれぞれ誘導する因子の解析2012

    • Author(s)
      刀祢重信, 杉本憲治, 網代廣三, 栗林太
    • Organizer
      第21回日本Cell Death学会
    • Place of Presentation
      名古屋市
    • Year and Date
      2012-07-27
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] アポトーシスにおける核凝縮の3つの素過程リング、ネックレス、核崩壊をそれぞれ誘導する因子の解析- Cell-free系を用いて2012

    • Author(s)
      刀祢重信, 杉本憲治, 網代廣三, 栗林太
    • Organizer
      第35回日本分子生物学年会
    • Place of Presentation
      福岡市
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] アポトーシスにおける核凝縮の3つの素過程リング、ネックレス、核崩壊を試験管内で再現する2012

    • Author(s)
      刀祢重信, 杉本憲治, 網代廣三, 栗林太
    • Organizer
      第53回日本生化学会中四国支部例会
    • Place of Presentation
      岡山市
    • Year and Date
      2012-05-18
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] アポトーシスにおける核凝縮の分子機構2011

    • Author(s)
      刀祢重信
    • Organizer
      第67回日本顕微鏡学会シンポジウム
    • Place of Presentation
      福岡市
    • Year and Date
      2011-05-16
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] Proapoptotic Role of DNA-PK System in DT40 Apoptosis Induced by X-ray, UV or Hydrogen Peroxide2010

    • Author(s)
      Tone S, Kuribayashi F, Takata M, Ishiai M.
    • Organizer
      American Society of Cell Biology
    • Place of Presentation
      フィラデルフィア(米国)
    • Year and Date
      2010-12-13
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Presentation] 特別講演 プログラムされた細胞死 アポトーシス2010

    • Author(s)
      刀祢重信
    • Organizer
      大阪府立大学ライブセルイメージング研究所設立4周年記念シンポジウム
    • Place of Presentation
      大阪府堺市
    • Year and Date
      2010-02-01
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Presentation] Proapoptotic Role of DNA-PK System in DT40 Apoptosis Induced by X-ray2010

    • Author(s)
      Tone S, Kuribayashi F, Takata M, Ishiai M
    • Organizer
      UV or Hydrogen Peroxide American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Presentation] 細胞死関連マルチパラメーターの自動連続測定法-Image Xpress を用いて2009

    • Author(s)
      刀祢重信
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Presentation] ワークショップ アポトーシス検出法 ―初歩から最先端まで 1)アポトーシスの検出法 まずこれをやってみたら?2009

    • Author(s)
      刀祢重信
    • Organizer
      第18回日本アポトーシス研究会学術集会
    • Place of Presentation
      長崎市
    • Year and Date
      2009-08-01
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Presentation] Ku70 and DNA-PKcs are essential in DT40 apoptosis inducedby X-ray, UV or H2O2.2009

    • Author(s)
      Tone S
    • Organizer
      Keystone Symposium on "Cell Death Pathways"
    • Place of Presentation
      Wistler (Canada)
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Presentation] 細胞を救うはずのDNA修復酵素DNA-PKは、細胞自らが死ぬために必要である2009

    • Author(s)
      刀祢重信
    • Organizer
      第8回核ダイナミクス研究会
    • Place of Presentation
      静岡県伊豆市
    • Year and Date
      2009-06-19
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Presentation] Ku70 and DNA-PKcs are essential in DT40 apoptosis induced by X-ray2009

    • Author(s)
      Tone S, Tanda K Takata M Ishiai M
    • Organizer
      UV or H2O2 Keystone Symposia Conference "Cell Death Pathways"
    • Place of Presentation
      Whistler, Canada
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Presentation] Dynamic aspects of nuclear condensation revealed by time-lapse imaging, biochemical and electron microscopy analysis of cell-free apoptosis.2007

    • Author(s)
      Tone S, Tanda K Sugimoto K Suda T Uehira K, Kanouchi H Samejima K Minatogawa Y, Earnshaw W C
    • Organizer
      EMBO Conference Series on Nuclear Structure & Dynamics.
    • Place of Presentation
      Montpelier, France
    • Data Source
      KAKENHI-PROJECT-20590203
  • [Presentation] アポトーシスにおける核凝縮の3つの素過程 リング、ネックレス、核崩壊をそれぞれ誘導する因子の解析

    • Author(s)
      刀祢重信, 杉本憲治, 網代廣三, 栗林太
    • Organizer
      第21回 日本Cell Death 学会
    • Place of Presentation
      名古屋大学(名古屋市)
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] Analysis of factors involving three distinct stages during apoptotic nuclear condensation using a cell-free system

    • Author(s)
      Tone S, Sugimoto K, Ajiro K, Kuribayashi F
    • Organizer
      52th American Society for Cell Biology (ASCB )
    • Place of Presentation
      Moscone Center (サンフランシスコ, USA)
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] Semi-complete reconstitution of apoptotic nuclear machinery

    • Author(s)
      Tone, S, Norimoto, T, Sugimoto, K, Ajiro, K, Kuribayashi, F
    • Organizer
      53rd American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Morial Center(ニューオリンズ市)
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] アポトーシスに見る自己集合現象

    • Author(s)
      刀祢重信
    • Organizer
      第36回日本分子生物学会年会ワークショップ 「生命における自己組織化のメカニズム」
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] 細胞死のプログラムの解読 死のシグナルから死の実行まで

    • Author(s)
      刀祢重信
    • Organizer
      鹿児島大学第1回分子病態学セミナー
    • Place of Presentation
      鹿児島大学(鹿児島市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] アポトーシスにおける核凝縮の分子形態学的アプローチ

    • Author(s)
      刀祢重信
    • Organizer
      第67回日本顕微鏡学会 シンポジウム 細胞死の分子機構(招待講演)
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-23570083
  • [Presentation] アポトーシスにおける核凝縮の3つの素過程 リング、ネックレス、核崩壊をそれぞれ誘導する因子の解析 - Cell-free系を用いて

    • Author(s)
      刀祢重信, 杉本憲治, 網代廣三, 栗林太
    • Organizer
      第35回日本分子生物学会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Data Source
      KAKENHI-PROJECT-23570083
  • 1.  SENBA Emiko (00135691)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  TAKIKAWA Osamu (70163342)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  OKAMOTO Takeaki (20398431)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 4.  UEYAMA Takashi (50264875)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KAWAI Yoshinori (80211861)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  YOSHIDA Ryotaro (10124760)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  KURIHARA Keiko (90124495)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  Ejima Takeo (80261478)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 9.  湊川 洋介 (50094678)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  小池 達郎 (80128131)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  田中 秀逸 (90202431)
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  • 55.  渡部 和彦
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  • 56.  後藤 志信
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