NAKATANI Kazuhiko 中谷和彦

Researcher Number	70237303
Other IDs
Affiliation (Current)	2025: 大阪大学, 産業科学研究所, 特任教授(常勤)
Affiliation (based on the past Project Information) *help	2018 – 2024: 大阪大学, 産業科学研究所, 教授 2005 – 2016: Osaka University, The Institute of Scientific and Industrial Research, Professor, 産業科学研究所, 教授 2008: 阪大, 産業科学研究所, 教授 1997 – 2004: Kyoto University, Faculty of Engineering, Associate Professor., 工学研究科, 助教授 1996: Kyoto University, Faculty of Engineering, Assistant Professor, 工学研究所, 助手 1995 – 1996: 京都大学, 工学研究科, 助手 1993 – 1994: 京都大学, 工学部, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Medium-sized Section 37:Biomolecular chemistry and related fields / Bioorganic chemistry / Bio-related chemistry / Chemistry related to living body / Applied genomics / Human genetics / 工業物理化学 / Chemistry / Science and Engineering … More / Chemical biology / Neurochemistry/Neuropharmacology / Synthetic chemistry / Organic chemistry … More Except Principal Investigator Analytical chemistry / Chemical biology / Synthetic chemistry / Synthetic chemistry / Bioorganic chemistry / 天然物有機化学 / Chemistry related to living body / Chemical biology / Functional materials/Devices Less
Keywords	Principal Investigator DNA / ミスマッチ / SNP / ナフチリジン / 低分子 / 遺伝子疾患 / 結合分子 / RNA / トリプレットリピート / テロメア … More / 分子認識 / シトシン / 異常伸長 / リピート / 修復酵素 / 化学修飾 / ループ / 小分子 / 機能化学 / 生体認識 / 分子 / 核酸 / CGGリピート / SNPs / ラジカルカチオン / シクロプロピルグアニン / 電子移動 / SPR / G-Gミスマッチ / アルキル化 / 素子 / 電界効果型トランジスタ / 認識 / シーケンサ / ナノポア / 短縮機構解明 / 経路探索 / スリップアウト構造 / 短縮 / デアミナーゼ / リピート短縮 / リピート配列 / リピート病 / 計算科学 / 複合体形成過程 / 低分子複合体 / 計算機科学 / 形成過程 / 量子化学計算 / 形成経路 / 複合体 / 量子計算 / 誘導適合 / 創薬 / 標的 / Genetic Disease / Trinucleotide Repeat / CAGリピート / recognition / mismatch / 表面プラズモン共鳴 / ナフチリジンダイマー / cyclopropyl / hole transport / ラジカルカオチン / ホール検出手法 / Homo / Alkylation / Guamine / エポキシド / 配列選択性 / GG / インターカレーション / HOMO / GG配列 / グアニン / Guanine / oligopeptide / Photocrosslinking / オリゴペプチド / 光クロスリンク基 / プロープ / RNA機能調節 / 伸長抑制 / プローブ / 分子合成 / スクリーニング / 分子設計 / 毒性RNA / 神経変性疾患 / 核酸結合低分子 / トリヌクレオチドリピート / 電荷移動錯体 / loop / pre-miRNA / 阻害 / Dicer / 構造変化 / マイクロRNA / ヘアピン / インビトロセレクション / 8位置換プリン / ライブラリー / ８位置換プリン化合物 / doped library / リボスイッチ / in vivo セレクション / ８位置換プリン誘導体 / reengineering / riboswitch / chemical library / 8-substituted purine / synthesis / 機能制御 / スイッチ / 塩基対 / 光応答 / 機能発現 / 核酸構造 / 光異性化 / 会合体 / ヘアピンループ / 制御 / 高次構造 / ナノテクノロジー / DNAナノ構造 / 光制御 / TRAPアッセイ / がん細胞パネル / コールドスプレーイオン化 / テロメアノット / テロメラーゼ / アザキノロン / 遺伝子変異 / 分子リガンド / 抗生物質カプリマイシンA_3 / ビニルエポキシド側鎖 / アルデヒドユニット / カプリマイシンA3 / 分子軌道計算 / エキソ四置換二重結合 / ビニルシラン / ヒドロキシシラン … More Except Principal Investigator DNA / 蛍光分子 / PCR / RT-PCR / epoxide / guanine N7 / DNA alkylation / メ-ジャーグループ / グアニン / カプリマイシンA_3 / DNA切断 / バイオテクノロジー / 分子認識 / 一塩基多型 / シトシンバルジ構造 / シトシンバルジ / 分子設計 / 遺伝子 / 有機化学 / HP－PCR / ヘアピンプローブPCR / マイクロRNA / miRNA / fluorescence molecule / reverse transcription / へアピンプライマー / ウイルス検出 / 遺伝子検出 / carbon monoxide / cyclic carbonvlation / transition metal catalyst / modified nucleoside / 修飾ヌクレシド / カルボニル化反応 / 遷移金属錯体 / 修飾ヌクネオシド / 一酸化炭素 / 環化カルボニル化反応 / 遷移金属触媒 / 修飾ヌクレオシド / Cvtosine bulge / Fluorescent molecule / SNP / cross-linking / Kapurmycin A3 / オキシラニルメトキシアントランセン / 抗腫瘍性抗生物質 / クロスリンク / エポキシド / グアニンN7位 / DNAアルチル化 / major groove / antitumor antibiotic / kapurimycin A_3 / メ-ジャーグルーブ / アンチモアアンチバイオティック / エポキサイド / DNA Cleavage / Neocarzinostatin / Bleomycins / Antitumor Antibiotics / DNA Cleaver / DNA Recognition / ハイブリッド蛋白 / 人工制限酵素 / DNA認識蛋白 / オリゴタクレオチド / DNA切断分子 / 人工蛋白質 / 超分子 / 抗ガン剤 / RNA結合リガンド / 生体認識・機能化学 / 光スイッチ / 分子糊 / ミスマッチ / RNA / ケミカルバイオロジー / ヘアピン構造 / SNPタイピング / 蛍光 / ヘアピンプライマー / ナノ複合体 / 時間空間制御 / ハードマテリアル / ソフトマテリアル / 生体分子デバイス / ハイブリット化 / 生体分子 Less

Elucidation of the binding pathway of mismatch-binding molecules to abnormally elongated repeat sequences and their shortening-inducing effectsPrincipal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University
Challenge in computational science toward the identification of the reaction pathway for the formation of nucleic acids-small molecule complexesPrincipal Investigator
- Principal Investigator
  
  Nakatani Kazuhiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University
Creation of repeat binding molecules that specifically modify repeat sequences chemicallyPrincipal Investigator
- Principal Investigator
  
  Nakatani Kazuhiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University
Development of novel microRNA detection system
- Principal Investigator
  
  TAKEI FUMIE
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Analytical chemistry
- Research Institution
  National Defense Medical College
Chemical Biology Studies on Trinucleotide Repeat Disease using Repeat-Binding MoleculesPrincipal Investigator
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2014 – 2019
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Osaka University
ナノポアシーケンサーにおける一塩基分解能を達成する塩基読み取り分子に関する研究Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka University
Determination of molecular mechanism of loop-specific structural change and inhibitory effect for Dicer mediated reactionPrincipal Investigator
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka University
Regulation of secondary structure by RNA loop-loop interaction inducedsmall molecular bindingPrincipal Investigator
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
Novel high-sensitivity detection method of virus using a hairpin primer PCR
- Principal Investigator
  
  Fumie Takei
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical biology
- Research Institution
  National Defense Medical College
  Osaka University
Synthesis of 8-substituted purine chemical library and riboswitch-reengineeringPrincipal Investigator
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Photoresponsive RNA-binding ligands for regulation of RNA functions
- Principal Investigator
  
  DHONO Chikara
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
Application for the fluorescent detection of single nucleotide difference using cytosine bulge hairpin primers
- Principal Investigator
  
  TAKEI Fumie
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Functional Control by Modulating the Nucleic Acid Structure Based on Mismatch Base Pair StabilizationPrincipal Investigator
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
Fluorescent Determination of SNPs by C-Bulge binding ligand
- Principal Investigator
  
  TAKEI Fumie
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Analytical chemistry
- Research Institution
  Osaka University
Synthesized cyclic nucleosides mid oligo library by catalyst
- Principal Investigator
  
  ZHOU Da-Yang
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Osaka University
CAGリピート結合リガンドの発見に基づいたリピート伸長抑制Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
ハイブリット生体分子デバイスの創製と応用技術
- Principal Investigator
  
  藤塚守
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional materials/Devices
- Research Institution
  Osaka University
SNPs探索分子素子(ミスマッチ結合分子リガンド)の開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
新しい概念「テロメアノット」形成に基づいたテロメラーゼ阻害剤の開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ハンチントン病発症予防-CAGリピートエクスパンジョンを抑制するドラッグの開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
  Kyoto University
SNPs探索分子素子(ミスマッチ結合分子リガンド)の開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
新しい概念「テロメアノット」形成に基づいたテロメラーゼ阻害剤の開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Molecular Design of Drugs recognizing Trinucleotide Repeat Sequence.Principal Investigator
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied genomics
- Research Institution
  Osaka University
  Kyoto University
SNPs探索分子素子(ミスマッチ結合分子リガンド)の開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
新しい概念「テロメアノット」形成に基づいたテロメラーゼ阻害剤の開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
SNPs探索分子素子(ミスマッチ結合分子リガンド)の開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
新しい概念「テロメアノット」形成に基づいたテロメラーゼ阻害剤の開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
シクロプロピルグアニンによるDNAホールトラップ反応の開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Synthetic chemistry
- Research Institution
  Kyoto University
Modulation of DNA mediated hole transport by novel substituents on DNAPrincipal Investigator
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  工業物理化学
- Research Institution
  KYOTO UNIVERSITY
Studies on a rapid detection system of SNPs using mismatch-binding moleculesPrincipal Investigator
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Kyoto University
ミスマッチ構造認識分子を活用するSNPs探索システムの構築Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
SNPs探索分子素子(ミスマッチ結合分子リガンド)の開発Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Molecular Design of Nobel DNA Alkylating Agent at GG stepPrincipal Investigator
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  KYOTO UNIVERSITY
抗生物質カプリマイシンA_3の全合成に基づくDNAとの高次構造複合体形成機構の解明Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
抗生物質カプリマイシンA3の全合成に基づくDNAとの高次構造複合体形成機構の解明Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Investigation of DNA Binding OligopeptidePrincipal Investigator
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  KYOTO UNIVERSITY
Molecular Design of Autitumor Autibiotic by DNA double Crosslinking.
- Principal Investigator
  
  SAITO Isao
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Synthetic chemistry
- Research Institution
  KYOTO UNIVERSITY
Elucidation of structure of antitumor antibiotic kapurimycin A3 and reactivity toward DNA
- Principal Investigator
  
  SAITO Isao
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  KYOTO UNIVERSITY
酸素とケイ素の親和力を利用したビニルシランの立体制御。立体選択的exo-四置換二重結合生成への展開Principal Investigator
- Principal Investigator
  
  中谷和彦
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Organic chemistry
- Research Institution
  Kyoto University
Design of Biofunctional Molecules based on Molecular Recognition
- Principal Investigator
  
  SAITO Isao
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  天然物有機化学
- Research Institution
  KYOTO UNIVERSITY

[Book] Modified Nucleic Acids, Nucleic Acids and Molecular Biology 312016
- Author(s)
  Kazuhiko Nakatani and Yitzhak Tor, Editor
- Total Pages
  275
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26000007
[Book] ゲノム化学2007
- Author(s)
  齋藤烈、杉山弘、中谷和彦
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-18105006
[Book] ゲノム化学2007
- Author(s)
  齋藤烈、杉山弘、中谷和彦編
- Total Pages
  214
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] A small molecule binding to TGGAA pentanucleotide repeats that cause spinocerebellar ataxia type 312023
- Author(s)
  Shibata Tomonori、Nakatani Kazuhiko
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 79 Pages: 129082-129082
- DOI
  10.1016/j.bmcl.2022.129082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19049, KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-20H02880, KAKENHI-PROJECT-22H00351
[Journal Article] Intracerebral Distribution of CAG Repeat-Binding Small Molecule Visualized by Whole-Brain Imaging2023
- Author(s)
  Murakami Eitaro、Nakamori Masayuki、Nakatani Kazuhiko、Shibata Tomonori、Tainaka Kazuki
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 34 Issue: 12 Pages: 2187-2193
- DOI
  10.1021/acs.bioconjchem.3c00470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22597, KAKENHI-PROJECT-21K19049, KAKENHI-PROJECT-22H00351, KAKENHI-PROJECT-23K24198
[Journal Article] Possibilities and challenges of small molecule organic compounds for the treatment of repeat diseases2022
- Author(s)
  NAKATANI Kazuhiko
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 98 Issue: 1 Pages: 30-48
- DOI
  10.2183/pjab.98.003
- NAID
  130008140767
- ISSN
  0386-2208, 1349-2896
- Year and Date
  2022-01-11
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22254, KAKENHI-PROJECT-19H00924
[Journal Article] HT-SELEX-based identification of binding pre-miRNA hairpin-motif for small molecules2022
- Author(s)
  Mukherjee Sanjukta、Murata Asako、Ishida Ryoga、Sugai Ayako、Dohno Chikara、Hamada Michiaki、Krishna Sudhir、Nakatani Kazuhiko
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 27 Pages: 165-174
- DOI
  10.1016/j.omtn.2021.11.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05879, KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K22254, KAKENHI-PROJECT-17K20032, KAKENHI-PROJECT-19H00924
[Journal Article] Method for Identifying Sequence Motifs in Pre-miRNAs for Small-Molecule Binding2022
- Author(s)
  Takashima Yusuke、Murata Asako、Iida Kei、Sugai Ayako、Hagiwara Masatoshi、Nakatani Kazuhiko
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 17 Issue: 10 Pages: 2817-2827
- DOI
  10.1021/acschembio.2c00452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-23K21158
[Journal Article] CAG repeat-binding small molecule improves motor coordination impairment in a mouse model of Dentatorubral?pallidoluysian atrophy2022
- Author(s)
  Hasuike Yuhei、Tanaka Hana、Gall-Duncan Terence、Mehkary Mustafa、Nakatani Kazuhiko、Pearson Christopher E.、Tsuji Shoji、Mochizuki Hideki、Nakamori Masayuki
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 163 Pages: 105604-105604
- DOI
  10.1016/j.nbd.2021.105604
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22597, KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-23K21411
[Journal Article] Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit2022
- Author(s)
  Hsu Hsiu-Ting、Murata Asako、Dohno Chikara、Nakatani Kazuhiko、Chang KungYao
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 9 Pages: 5369-5383
- DOI
  10.1093/nar/gkac257
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107
[Journal Article] Mismatch binding ligand upregulated back-splicing reaction producing circular RNA in a cellular model2022
- Author(s)
  Ni Lu、Yamada Takeshi、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  Chemical Communications
  
  Volume: 58 Issue: 22 Pages: 3629-3632
- DOI
  10.1039/d1cc06936e
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05693, KAKENHI-PROJECT-22K05315, KAKENHI-PROJECT-19H00924
[Journal Article] Inhibitory Effects of Mismatch Binding Molecules on the Repair Reaction of Uracil-Containing DNA2022
- Author(s)
  Ulhusna Anisa、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  Biochemistry
  
  Volume: 61 Issue: 22 Pages: 2522-2530
- DOI
  10.1021/acs.biochem.2c00344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-22H00351, KAKENHI-PROJECT-23K21158
[Journal Article] NMR determination of the 2:1 binding complex of naphthyridine carbamate dimer (NCD) and CGG/CGG triad in double-stranded DNA2022
- Author(s)
  Yamada Takeshi、Furuita Kyoko、Sakurabayashi Shuhei、Nomura Makoto、Kojima Chojiro、Nakatani Kazuhiko
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 17 Pages: 9621-9631
- DOI
  10.1093/nar/gkac740
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05315, KAKENHI-PUBLICLY-22H05536, KAKENHI-PROJECT-20H03191, KAKENHI-PROJECT-19H00924
[Journal Article] Cyclic mismatch binding ligands interact with disease-associated CGG trinucleotide repeats in RNA and suppress their translation2021
- Author(s)
  Konieczny Patryk、Mukherjee Sanjukta、Stepniak-Konieczna Ewa、Taylor Katarzyna、Niewiadomska Daria、Piasecka Agnieszka、Walczak Agnieszka、Baud Anna、Dohno Chikara、Nakatani Kazuhiko、Sobczak Krzysztof
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 16 Pages: 9479-9495
- DOI
  10.1093/nar/gkab669
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107
[Journal Article] A small-molecule fluorescence probe ANP77 for sensing RNA internal loop of C, U and A/CC motifs and their binding molecules2021
- Author(s)
  Das Bimolendu、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 15 Pages: 8462-8470
- DOI
  10.1093/nar/gkab650
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19H00924
[Journal Article] Speeding drug discovery targeting RNAs: An iterative “RNA selection-compounds screening cycle“ for exploring RNA-small molecule pairs2021
- Author(s)
  Furuzono Tomoko、Murata Asako、Okuda Satoshi、Mizutani Kenji、Adachi Tsuyoshi、Nakatani Kazuhiko
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 36 Pages: 116070-116070
- DOI
  10.1016/j.bmc.2021.116070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19H00924
[Journal Article] Small Molecule-Induced Dimerization of Hairpin RNA Interfered with the Dicer Cleavage Reaction2021
- Author(s)
  Murata Asako、Mori Yuki、Di Yue、Sugai Ayako、Das Bimolendu、Takashima Yusuke、Nakatani Kazuhiko
- Journal Title
  
  Biochemistry
  
  Volume: 60 Issue: 4 Pages: 245-249
- DOI
  10.1021/acs.biochem.0c00920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19H00924
[Journal Article] Rational design of a photoswitchable DNA glue enabling high regulatory function and supramolecular chirality transfer2021
- Author(s)
  Simeth Nadja A.、Kobayashi Shotaro、Kobauri Piermichele、Crespi Stefano、Szymanski Wiktor、Nakatani Kazuhiko、Dohno Chikara、Feringa Ben L.
- Journal Title
  
  Chemical Science
  
  Volume: 12 Issue: 26 Pages: 9207-9220
- DOI
  10.1039/d1sc02194j
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107
[Journal Article] Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model2021
- Author(s)
  Shibata Tomonori、Nagano Konami、Ueyama Morio、Ninomiya Kensuke、Hirose Tetsuro、Nagai Yoshitaka、Ishikawa Kinya、Kawai Gota、Nakatani Kazuhiko
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41467-020-20487-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06478, KAKENHI-PROJECT-19K22254, KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-17K01962, KAKENHI-PLANNED-20H05927, KAKENHI-PROJECT-20H00448, KAKENHI-PROJECT-20H02880
[Journal Article] Short Tandem Repeat Contractions during In Vitro DNA Synthesis by Repeat-binding Molecules2021
- Author(s)
  Hagihara Masaki、Dohno Chikara、Saito Kaoru、Sugimoto Kazuhiro、Hishinuma Yuta、Sohma Yuri、Shibata Tomonori、Nakatani Kazuhiko
- Journal Title
  
  Chemistry Letters
  
  Volume: 50 Issue: 11 Pages: 1848-1851
- DOI
  10.1246/cl.210415
- NAID
  130008113718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-20H02880
[Journal Article] 2-Amino-1,8-naphthyridine Dimer (ANP77), a High-Affinity Binder to the Internal Loops of C/CC and T/CC Sites in Double-Stranded DNA2021
- Author(s)
  Das Bimolendu、Nagano Konami、Kawai Gota、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 87 Issue: 1 Pages: 340-350
- DOI
  10.1021/acs.joc.1c02383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19H00924
[Journal Article] FAN1 exo- not endo-nuclease pausing on disease-associated slipped-DNA repeats: A mechanism of repeat instability2021
- Author(s)
  Deshmukh Amit Laxmikant、Caron Marie-Christine、Mohiuddin Mohiuddin、Lanni Stella、Panigrahi Gagan B.、Khan Mahreen、Engchuan Worrawat、Shum Natalie、Faruqui Aisha、Wang Peixiang、Yuen Ryan K.C.、Nakamori Masayuki、Nakatani Kazuhiko、Masson Jean-Yves、Pearson Christopher E.
- Journal Title
  
  Cell Reports
  
  Volume: 37 Issue: 10 Pages: 110078-110078
- DOI
  10.1016/j.celrep.2021.110078
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-19K22597
[Journal Article] Small molecule-induced trinucleotide repeat contractions during <i>in vitro</i> DNA synthesis2021
- Author(s)
  Dohno Chikara、Hagihara Masaki、Binti Mohd Zaifuddin Nursakinah、Nihei Mizuki、Saito Kaoru、Nakatani Kazuhiko
- Journal Title
  
  Chemical Communications
  
  Volume: 57 Issue: 26 Pages: 3235-3238
- DOI
  10.1039/d1cc00349f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107
[Journal Article] The dimeric form of 1, 3 - diaminoisoquinoline derivative rescued the mis - splicing of Atp2a1 and Clcn1 genes in myotonic dystrophy type 1 mouse model2020
- Author(s)
  Matsumoto, J. ; Nakamori, M. ; Okamoto, T. ; Murata, A. ; Dohno, C. ; Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 26 Issue: 63 Pages: 14305-14309
- DOI
  10.1002/chem.202001572
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K22597, KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-16H05321
[Journal Article] Chemical Probing of Thymine in the TGG/CGG Triad to Explore the Deamination of 5-Methylcytosine in the CGG Repeat2020
- Author(s)
  Yagi Yuki、Yamada Takeshi、Nakatani Kazuhiko
- Journal Title
  
  Biochemistry
  
  Volume: 59 Issue: 29 Pages: 2679-2683
- DOI
  10.1021/acs.biochem.0c00333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05693, KAKENHI-PROJECT-19K22254, KAKENHI-PROJECT-19H00924
[Journal Article] Assembly of ruthenium complexes on double strand DNA using mismatch binding ligand2020
- Author(s)
  Ni, L. ; Yamada, T. ; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 56 Issue: 1 Pages: 56-61
- DOI
  10.1016/j.bbrc.2020.03.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-18H02107
[Journal Article] Novel Naphthyridine Tetramer that Recognizes Tandem G-G Mismatches by Formation of Interhelical Complex2020
- Author(s)
  Lu, Y. ; Dohno, C. ; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 56 Issue: 5 Pages: 754-757
- DOI
  10.1039/c9cc08111a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-18H02107
[Journal Article] A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo2020
- Author(s)
  Nakamori Masayuki, Panigrahi Gagan B., Lanni Stella, et. al.
- Journal Title
  
  Nature Genetics
  
  Volume: 52 Issue: 2 Pages: 146-159
- DOI
  10.1038/s41588-019-0575-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K07992, KAKENHI-PROJECT-19K22597, KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-16H05321
[Journal Article] RT‐Hpro‐PCR: A MicroRNA Detection System Using a Primer with a DNA Tag2019
- Author(s)
  Takei Fumie、Akiyama Misaki、Murata Asako、Sugai Ayako、Nakatani Kazuhiko、Yamashita Ichiro
- Journal Title
  
  ChemBioChem
  
  Volume: 21 Issue: 4 Pages: 477-480
- DOI
  10.1002/cbic.201900382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K05534, KAKENHI-PROJECT-26000007
[Journal Article] Modulating RNA secondary and tertiary structures by mismatch binding ligands2019
- Author(s)
  Murata Asako、Nakamori Masayuki、Nakatani Kazuhiko
- Journal Title
  
  Methods
  
  Volume: 167 Pages: 78-91
- DOI
  10.1016/j.ymeth.2019.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K22597, KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-16H05321
[Journal Article] Structural insights into synthetic ligands targeting A?A pairs in disease-related CAG RNA repeats2019
- Author(s)
  Mukherjee Sanjukta、Blaszczyk Leszek、Rypniewski Wojciech、Falschlunger Christoph、Micura Ronald、Murata Asako、Dohno Chikara、Nakatani Kazuhiko、Kiliszek Agnieszka
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Issue: 20 Pages: 10906-10913
- DOI
  10.1093/nar/gkz832
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-26000007
[Journal Article] Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136?BzDANP?Dicer2019
- Author(s)
  Otabe Takahiro、Nagano Konami、Kawai Gota、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 10 Pages: 2140-2148
- DOI
  10.1016/j.bmc.2019.03.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-26000007
[Journal Article] Molecular glue for RNA: Regulating RNA structure and function through a synthetic RNA binding molecule2019
- Author(s)
  Dohno, C.; Nakatani, K.
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Issue: 23 Pages: 2903-2910
- DOI
  10.1002/cbic.201900223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-26000007
[Journal Article] Bicyclic and tricyclic C-C mismatch-binding ligands bind to CCG trinucleotide repeat DNAs2018
- Author(s)
  Shibata, T. ; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 54 Issue: 51 Pages: 7074-7077
- DOI
  10.1039/c8cc02393j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting2018
- Author(s)
  Matsumoto Saki、Caliskan Neva、Rodnina Marina V、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 46 Issue: 16 Pages: 8079-8089
- DOI
  10.1093/nar/gky689
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-15K01820, KAKENHI-PROJECT-26000007
[Journal Article] A Dimeric 2,9‐Diamino‐1,10‐phenanthroline Derivative Improves Alternative Splicing in Myotonic Dystrophy Type 1 Cell and Mouse Models2018
- Author(s)
  Li Jinxing、Nakamori Masayuki、Matsumoto Jun、Murata Asako、Dohno Chikara、Kiliszek Agnieszka、Taylor Katarzyna、Sobczak Krzysztof、Nakatani Kazuhiko
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: 24 Issue: 68 Pages: 18115-18122
- DOI
  10.1002/chem.201804368
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-15K15339, KAKENHI-PROJECT-16H05321, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-17J02038, KAKENHI-PROJECT-26000007
[Journal Article] CGG repeat DNA assisted dimerization of CGG/CGG binding molecule through intermolecular disulfide formation2018
- Author(s)
  Yamada Takeshi、Miki Shouta、Ni Lu、Nakatani Kazuhiko
- Journal Title
  
  Chemical Communications
  
  Volume: 54 Issue: 93 Pages: 13072-13075
- DOI
  10.1039/c8cc06757k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14516, KAKENHI-PROJECT-26000007
[Journal Article] Fluorescence turn-on hairpin-probe PCR2018
- Author(s)
  Takei, F.; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 53 Issue: 8 Pages: 1393-1396
- DOI
  10.1039/c6cc08947j
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14027, KAKENHI-PROJECT-26000007
[Journal Article] Relative stability between the manganese hydroxide- and oxo-models for water oxidation by CCSD, DMRG CASCI, CASSCF, CASPT2 and CASDFT methods; Importance of static and dynamical electron correlation effects for OEC of PSII2018
- Author(s)
  Kawakami T.、Miyagawa K.、Isobe H.、Shoji M.、Yamanaka S.、Katouda M.、Nakajima T.、Nakatani K.、Okumura M.、Yamaguchi K.
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 705 Pages: 85-91
- DOI
  10.1016/j.cplett.2018.05.046
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06434, KAKENHI-PUBLICLY-18H05167, KAKENHI-PROJECT-26000007
[Journal Article] 1, 3-Di(quinolin-2-y1) guanidine binds to GGCCCC hexanucleotide repeat DNA in C90RF722018
- Author(s)
  Shibata, T. ; Murakami, E. ; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 28 Issue: 14 Pages: 2364-2368
- DOI
  10.1016/j.bmcl.2018.06.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] PCR under Low Ionic Concentration Buffer Conditions2018
- Author(s)
  Takei, F. ; Akiyama, M. ; Nobusawa, K. ; Sabani, Norhayati Binti ; Han, H. ; Nakatani, K. ; Yamashita, I.
- Journal Title
  
  Chemistryselect
  
  Volume: 3 Issue: 3 Pages: 973-976
- DOI
  10.1002/slct.201702542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-16K14027
[Journal Article] Restoration of Ribozyme Tertiary Contact and Function by Using a Molecular Glue for RNA2018
- Author(s)
  Dohno, C. ; Kimura, M. ; Nakatani, K.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 57 Issue: 2 Pages: 506-510
- DOI
  10.1002/anie.201709041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-18H02107
[Journal Article] Expanding chemical space of DNA-binding molecules with three base-binding units2018
- Author(s)
  Yagi, Y. ; Aikawa, H. ; Yamada, T. ; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 28 Issue: 17 Pages: 2894-2898
- DOI
  10.1016/j.bmcl.2018.07.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] Synthesis of naphthyridine dimers with conformational restriction and the binding to DNA and RNA2017
- Author(s)
  Nakatani, K. ; Natsuhara, N. ; Mori, Y. ; Mukherjee, S. ; Das, B. ; and Murata, A.
- Journal Title
  
  Chem. Asian J.
  
  Volume: 12 Issue: 23 Pages: 3077-3087
- DOI
  10.1002/asia.201701293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] Synthetic ligand promotes gene expression by affecting GC sequence in promoter2017
- Author(s)
  Matsumoto Saki、Iida Kei、Murata Asako、Denawa Masatsugu、Hagiwara Masatoshi、Nakatani Kazuhiko
- Journal Title
  
  Bioorganic & medicinal chemistry letters
  
  Volume: 27 Issue: 15 Pages: 3391-3394
- DOI
  10.1016/j.bmcl.2017.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01820, KAKENHI-PROJECT-26000007
[Journal Article] Amphiphilic DNA tiles for controlled insertion and 2D assembly on fluid lipid membranes: the effect on mechanical properties2017
- Author(s)
  Dohno, C.; Makishi, S.; Nakatani, K.; Contera, S
- Journal Title
  
  Nanoscale
  
  Volume: 9 Issue: 9 Pages: 3051-3058
- DOI
  10.1039/c6nr07084a
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12746, KAKENHI-PROJECT-26000007
[Journal Article] Design and synthesis of cyclic mismatch binding ligands (CMBLs) with variable linkers by ring closing metathesis and their photophysical and DNA repeat binding properties2017
- Author(s)
  Mukherjee, S. ; Dohno, C. ; Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 23 Issue: 47 Pages: 11385-11396
- DOI
  10.1002/chem.201702064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] Synthesis of Naphthyridine Carbamate Dimer (NCD) Derivatives Modified with Alkanethiol and Binding Properties of G?G Mismatch DNA2017
- Author(s)
  Yamada Takeshi、Miki Shouta、Ul’Husna Anisa、Michikawa Akiko、Nakatani Kazuhiko
- Journal Title
  
  Organic Letters
  
  Volume: 19 Issue: 16 Pages: 4163-4166
- DOI
  10.1021/acs.orglett.7b01632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14516, KAKENHI-PROJECT-15K17885, KAKENHI-PROJECT-26000007
[Journal Article] A Ligand that Targets CUG Trinucleotide Repeats2016
- Author(s)
  Li. J.; Matsumoto, J.; Bai, L.-P.; Murata, A.; Dohno, A.; Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 22 Issue: 42 Pages: 14881-14889
- DOI
  10.1002/chem.201602741
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01820, KAKENHI-PROJECT-26000007
[Journal Article] Synthesis of lH-pyrrolo [3,2-h] quinoline-8-amine derivatives that target CTG trinucleotide repeats2016
- Author(s)
  Matsumoto, J. ; Li, J. ; Dohno, C. ; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 11 Issue: 15 Pages: 3761-3764
- DOI
  10.1016/j.bmcl.2016.05.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] Fluorescence probe for detecting CCG trinucleotide repeat DNA expansion and slip-out2016
- Author(s)
  Shibata, T. ; Nakatani, K.
- Journal Title
  
  ChemBioChem
  
  Volume: 17 Issue: 18 Pages: 1685-1688
- DOI
  10.1002/cbic.201600200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] Naphthyridine-Benzoazaquinolone : Evaluation of tricyclic system for the binding to (CAG)n Repeat DNA and RNA2016
- Author(s)
  Fukuzumi, T. ; Murata, A. ; Aikawa, H. ; Harada, Y. ; Nakatani, K.
- Journal Title
  
  Chem. Asian. J.
  
  Volume: 21 Issue: 13 Pages: 1971-1981
- DOI
  10.1002/asia.201600527
- Description
  in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-15K01820
[Journal Article] Synthesis and photo-physical properties of fluorescence molecular probe for turn-ON type detection of cytosine bulge DNA2016
- Author(s)
  Verma, R.; Takei, F.; Nakatani, K.
- Journal Title
  
  Org. Lett.
  
  Volume: 18 Issue: 13 Pages: 3170-3173
- DOI
  10.1021/acs.orglett.6b01378
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14027, KAKENHI-PROJECT-26000007
[Journal Article] BzDANP, a small-molecule modulator of pre-miR-29a maturation by Dicer2016
- Author(s)
  Murata, A. ; Otabe, T. ; Zhang, J. ; Nakatani, K
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 11 Issue: 10 Pages: 2790-2796
- DOI
  10.1021/acschembio.6b00214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] Development of 2, 7-Diamino-1, 8-Naphthyridine (DANP) Anchored Hairpin Primers for RT-PCR Detection of Chikungunya Virus Infection2016
- Author(s)
  Chen, H. ; Parimelalagan, M. ; Takei, F. ; Hapuarachchi, H. C. ; Evelyn Siew-Chuan Koay, E. S. -C. ; Ng, L. C. ; Ho, P. S. ; Nakatani, K. ; Chu, J. J. H.
- Journal Title
  
  PLOS Negl. Trop. Dis
  
  Volume: 10 Issue: 8 Pages: e0004887-e0004887
- DOI
  10.1371/journal.pntd.0004887
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] A 2, 7-diamino-1, 4, 8-triazanaphthalene derivative selectively binds to cytosine bulge DNA only at a weakly acidic pH2016
- Author(s)
  Aikawa, H. ; Yano, A. ; Nakatani, K.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 15 Pages: 1313-1316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] Cyclic mismatch binding ligand CMBL4 binds to the 5'-T-3'/5'-GG-3' site by inducing the flipping out of thymine base2016
- Author(s)
  Mukherjee, S. ; Dohno, C. ; Asano, K. ; Nakatani, K.
- Journal Title
  
  Nucl. Acids Res.
  
  Volume: 44 Pages: 7090-7099
- DOI
  10.1093/nar/gkw672
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] 2-Aminophenanthroline dimer stabilized the C-C mismatched duplex DNA2015
- Author(s)
  Li, J.; Matsumoto, J. Otabe, K.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Issue: 4 Pages: 753-758
- DOI
  10.1016/j.bmc.2014.12.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-26000007
[Journal Article] Exploratory Study on the RNA-Binding Structural Motifs by Library Screening Targeting pre-miRNA-29a.2015
- Author(s)
  Fukuzumi, T.; Murata, A.; Aikawa, H.; Harada, Y.: Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 21 Issue: 47 Pages: 16859-16867
- DOI
  10.1002/chem.201502913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01820, KAKENHI-PROJECT-25750393, KAKENHI-PROJECT-26000007
[Journal Article] Detection of hepatitis C virus by single-step hairpin primer RT-PCR2014
- Author(s)
  Takei, F.; Tani, H.; Matsuura Y.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Issue: 1 Pages: 394-396
- DOI
  10.1016/j.bmcl.2013.10.021
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24310165
[Journal Article] Recognition of Chelerythrine to Human Telomeric DNA and RNA G-quadruplexes2014
- Author(s)
  Bai, L.-P.; Hagihara, M.; Nakatani, K.; Jiang, Z.-H.
- Journal Title
  
  Sci. Rep.
  
  Volume: 4 Issue: 1 Pages: 6767-6767
- DOI
  10.1038/srep06767
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-25350958, KAKENHI-PROJECT-26000007
[Journal Article] Formation of Ligand-Assisted Complex of Two RNA Hairpin Loops2014
- Author(s)
  Changfeng Hong, Takahiro Otabe, Saki Matsumoto, Chikara Dohno, Asako Murata, Masaki Hagihara, Kazuhiko Nakatani
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 20 Issue: 18 Pages: 5244-5252
- DOI
  10.1002/chem.201304683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J05460, KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-25350958, KAKENHI-PROJECT-26000007
[Journal Article] Cytosine-bulge dependent fluorescence quenching for real-time hairpin primer PCR2014
- Author(s)
  Takei, F.; Chen, X.; Yu, G.; Shibata, T.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 50 Issue: 96 Pages: 15195-15198
- DOI
  10.1039/c4cc06780k
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-24310165
[Journal Article] Synthesis of 8-substituted adenine and adenosine libraries and the binding to pre-miR-29a2014
- Author(s)
  Fukuzumi, T.; Aikawa, H.; Harada, Y.; Sugai, A.; Murata, A.; Nakatani, K.
- Journal Title
  
  Bull. Chem. Soc. Jpn.
  
  Volume: 87 Issue: 9 Pages: 1013-1015
- DOI
  10.1246/bcsj.20140137
- NAID
  130004687252
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-25750393, KAKENHI-PROJECT-26000007
[Journal Article] Modulation of binding properties of amphiphilic DNA containing multiple dodecyl phosphotriester linkages to lipid bilayer membrane2014
- Author(s)
  Makishi, S.; Shibata, T.; Okazaki, M.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Issue: 15 Pages: 3578-3581
- DOI
  10.1016/j.bmcl.2014.05.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-26000007
[Journal Article] Detection of hepatitis C virus by single-step hairpin primer RT-PCR2014
- Author(s)
  Takei, F.; Tani, H.; Matsuura Y.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Pages: 394-396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Ligand-inducible formation of RNA pseudoknot2013
- Author(s)
  Matsumoto, S., Hong, C; Otabe, T.; Murata, A.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Issue: 12 Pages: 3539-3541
- DOI
  10.1016/j.bmcl.2013.04.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-23710270, KAKENHI-PROJECT-25750393
[Journal Article] A synthetic riboswitch that operates using a rationally designed ligand-RNA pair2013
- Author(s)
  Dohno, C.; Kohyama, I.; Kimura, M.; Hagihara, M.; Nakatani, K.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 52 Issue: 38 Pages: 9976-9979
- DOI
  10.1002/anie.201303370
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-25350958
[Journal Article] Selective recognition of G-G mismatch using the double functional probe with electrochemical active ferrocenyl2013
- Author(s)
  He, H.; Xia, J.; Chang, G.; Peng, X.; Lou, Z.; Nakatani, K.; Zhou, X.; Wang, S.
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 42 Pages: 36-40
- DOI
  10.1016/j.bios.2012.10.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] A dimeric form of N-Methoxycarbonyl-2-amino-1,8-naphthyridine bound to the A-A mismatch in the CAG/CAG base triad in dsRNA2013
- Author(s)
  Nakatani, K.; Toda, M.; He, H. Bioorg
- Journal Title
  
  Med. Chem. Lett.
  
  Volume: 23 Pages: 558-561
- URL
  http://dx.doi.org/10.1016/j.bmcl.2012.11.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24655154
[Journal Article] Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: Targeting secondary structures of pre-miRNA by small molecules2013
- Author(s)
  Murata, A.; Fukuzumi, T.; Umemoto, S.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Pages: 252-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24655154
[Journal Article] Ligand-induced electron spin-assembly on a DNA tile2013
- Author(s)
  H. Atsumi, S. Nakazawa, C. Dohno, K. Sato, T. Takui, K. Nakatani
- Journal Title
  
  Chemical Communications
  
  Volume: 49 Issue: 57 Pages: 6370-6372
- DOI
  10.1039/c3cc41801d
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21102004, KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-23350011, KAKENHI-PROJECT-25410098
[Journal Article] Fluorescent indicator displacement assay of ligands targeting 10 microRNA precursors2013
- Author(s)
  Murata, A.; Harada, Y.; Fukuzumi, T.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Issue: 22 Pages: 7101-7106
- DOI
  10.1016/j.bmc.2013.09.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-23710270, KAKENHI-PROJECT-25750393
[Journal Article] G-quadruplex formation of entirely hydrophobic DNA in organic solvents2013
- Author(s)
  Shibata, T.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 49 Issue: 48 Pages: 5501-5503
- DOI
  10.1039/c3cc42221f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Triethynylmethane: A Molecular Unit Inducing Excimer-Like Emission in Aggregated States of Hydrocarbon Fluorophores2013
- Author(s)
  Otabe, T.; Matsumoto, S.; Nakagawa, H.; Hong, C.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Tetrahedron. Lett.
  
  Volume: 54 Pages: 143-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Facile electrochemical biosensor based on a new bifunctional probe for label-free detection of CGG trinucleotide repeat2013
- Author(s)
  He, H.; Xia, J. P.; Peng, X. Q.; Chang, G.; Zhang, X. H.; Wang, Y. F.; Nakatani, K.; Lou, Z. W.; Wang, S. F.
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 49 Pages: 282-289
- DOI
  10.1016/j.bios.2013.05.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] The Chemistry of PCR Primers: Concept and Application2013
- Author(s)
  Takei F, Nakatani K
- Journal Title
  
  ISRAEL JOURNAL OF CHEMISTRY
  
  Volume: 53 Issue: 6-7 Pages: 401-416
- DOI
  10.1002/ijch.201300027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310165
[Journal Article] High speed DNA denaturation using microheating devices2013
- Author(s)
  Furuhashi, M.; Okamoto, Y.; Onoshima, D.; Ohshiro, T.; Ryuzaki, S.; Yokota, K.; Tsutsui, M.; Taniguchi, M.; Nakatani, K.; Baba, Y.; Kawai, T.
- Journal Title
  
  Appl. Phys. Lett.
  
  Volume: 103 Pages: 023112-023112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] A Novel DANP-Coupled Hairpin RT-PCR for Rapid Detection of Chikungunya Virus.2013
- Author(s)
  Chen, H.; Takei, F.; Koay, E. S.-C.; Nakatani, K.; Chu, J. J. H.
- Journal Title
  
  J. Mol. Diagn.
  
  Volume: 15 Issue: 2 Pages: 227-233
- DOI
  10.1016/j.jmoldx.2012.10.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-24310165
[Journal Article] Selective recognition of G-G mismatch using the double functional probe with electrochemical active ferrocenyl2013
- Author(s)
  He, H.; Xia, J.; Chang, G.; Peng, X.; Lou, Z.; Nakatani, K.; Zhou, X.; Wang, S.
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 42 Pages: 36-40
- URL
  http://dx.doi.org/10.1016/j.bios.2012.10.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24655154
[Journal Article] Structure-activity studies on the fluorescent indicator in the displacement assay for the screening of small molecules binding to RNA2012
- Author(s)
  Umemoto, S.; Im, S.; Zhang, J.; Hagihara, M.; Murata, A.; Harada, Y.; Fukuzumi, T.; Wazaki, T.; Sasaoka, S.; Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 18 Pages: 9999-10008
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Activation of prokaryotic translation by antisense oligonucleotides binding to coding region of mRNA2012
- Author(s)
  Hayashi, G.; Hong, C.; Hagihara, M.; Nakatani, K.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 429 Pages: 105-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] A Small Molecule Regrulates Hairpin Structures in d(CGG) Trinucleotide Repeats2012
- Author(s)
  K.Nakatani, M.Hagihara, H.He, M.Kimura
- Journal Title
  
  Bioorg.Med.Chem.Lett.
  
  Volume: 22 Issue: 5 Pages: 2000-2003
- DOI
  10.1016/j.bmcl.2012.01.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Naphthyridine tetramer with a preorganized structure for 1:1 binding to a CGG/CGG sequence.2012
- Author(s)
  Dohno, C.; Kohyama, I.; Hong, C.; Nakatani, K.
- Journal Title
  
  Nucleic. Acids. Res.
  
  Volume: 40 Pages: 2771-2781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] A Small Molecule Regulates Hairpin Structures in d(CGG) Trinucleotide Repeats2012
- Author(s)
  Hagihara, M.; He, H.; Kimura, M.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 22 Pages: 2000-2003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Naphthyridine tetramer with a preorganized structure for 1:1 binding to a CGG/CGG sequence2012
- Author(s)
  Dohno, C.; Kohyama, I.; Hong, C; Nakatani, K.
- Journal Title
  
  Nucleic.Acids Res.
  
  Volume: 40 Issue: 6 Pages: 2771-2781
- DOI
  10.1093/nar/gkr1148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042, KAKENHI-PROJECT-24655154
[Journal Article] Assembly of a small DNA rectangular parallelepiped block into higher order nanostructures2012
- Author(s)
  Nakagawa, H.; Toda, M.; Atsumi, H.; Hagihara, M.; Hayashi-Nishino, M.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem. Lett.
  
  Volume: 41 Pages: 1550-1552
- NAID
  10031126595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Naphthyridine tetramer with a preorganized structure for 1:1 binding to a CGG/CGG sequence2011
- Author(s)
  Dohno, C.; Kohyama, I.; Hong, C.; Nakatani, K.
- Journal Title
  
  Nucleic. Acids. Res.
  
  Volume: 40 Pages: 2771-2781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Ligand Inducible Assembly of a DNA Tetrahedron2011
- Author(s)
  Dohno, C.; Atsumi, H.; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 47 Pages: 3499-3501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Molecular-Glue-Triggered DNA Assembly To Form a Robust and Photoresponsive Nano-Network2011
- Author(s)
  Wang, C.; Pu, F.; Lin, Y.; Ren, J.; Dohno, C.; Nakatani K.; Qu, X.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 17 Pages: 8189-8197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Ligand-Assisted Complex of Two DNA Hairpin Loops.2011
- Author(s)
  Hong, C.; Hagihara, M.; Nakatani, K.
- Journal Title
  
  Angewandte Chemi International Edition
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Control of DNA hybridization by photoswitchable molecular glue2011
- Author(s)
  Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem. Soc. Rev.
  
  Volume: 40 Pages: 5718-5729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Ligand Inducible Assembly of a DNA Tetrahedron.2011
- Author(s)
  Dohno, C.; Atsumi, H.; Nakatani, K.
- Journal Title
  
  Chem.Commun. 47
  
  Pages: 3499-3501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Ligand Inducible Assembly of a DNA Tetrahedron.2011
- Author(s)
  Dohno, C.; Atsumi, H.; Nakatani, K.
- Journal Title
  
  Chemical Communication
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Ligand-Assisted Complex of Two DNA Hairpin Loops.2011
- Author(s)
  Hong, C.; Hagihara, M.; Nakatani, K.Angew.
- Journal Title
  
  Chem.Int.Ed. 50
  
  Pages: 4390-4393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Control of DNA hybridization by photoswitchable molecular glue2011
- Author(s)
  Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem.Soc.Rev.
  
  Volume: 40 Issue: 12 Pages: 5718-5729
- DOI
  10.1039/c1cs15062f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Molecular-Glue-Triggered DNA Assembly to Form a Robust and Photore sponsive Nano-Network2011
- Author(s)
  Wang, C.; Pu, F.; Lin, Y.; Ren, J.; Dohno, C.; Nakatani K.; Qu, X.
- Journal Title
  
  Chem.Eur.J.
  
  Volume: 17 Issue: 29 Pages: 8189-8197
- DOI
  10.1002/chem.201100194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Non-covalent assembly of TEMPO radicals pair-wise embedded on a DNA duplex.2010
- Author(s)
  Atsumi, H.; Maekawa, K.; Nakazawa, S.; Shiomi, D.; Sato, K.; Kitagawa, M.; Takui, T., Nakatani, K.
- Journal Title
  
  Chemistry Letters
  
  Volume: (印刷中) Pages: 556-557
- NAID
  10027181105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Non-covalent assembly of TEMPO radicals pair-wise embedded on a DNA duplex.2010
- Author(s)
  Atsumi, H.; Maekawa, K.; Nakazawa, S.; Shiomi, D.; Sato, K.; Kitagawa, M.; Takui, T., Nakatani, K.
- Journal Title
  
  Chem.Lett.(Editor's Choice) 39
  
  Pages: 556-557
- NAID
  10027181105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Fluorescent Indicator-Displacement Assay for Ligand-RNA Interactions2010
- Author(s)
  Zhang, J.; Umemoto, S.; Nakatani, K.
- Journal Title
  
  J.Am.Chem.Soc. 132
  
  Pages: 3660-3661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Programmed Assembly of Organic Radicals on DNA.2010
- Author(s)
  Maekawa, K.; Nakazawa, S.; Atsumi, H.; Shiomi, D.; Sato, K.; Kitagawa, M.; Takui, T.; Nakatani, K.
- Journal Title
  
  Chem.Commun. 46
  
  Pages: 1247-1249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Antisense-Induced Guanine Quadruplexes Inhibit Reverse Transcription by HIV-1 Reverse Transcriptase.2010
- Author(s)
  Hagihara, M.; Yamauchi, L.; Seo, A.; Yoneda, K.; Senda, M.; Nakatani, K.
- Journal Title
  
  J.Am.Chem.Soc. 132
  
  Pages: 11171-11178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Transformation of cytosine to uracil in single-stranded DNA via their oxime sulfonates.2010
- Author(s)
  Oka, Y., Takei, F., Nakatani, K.
- Journal Title
  
  Chem.Commun. 46
  
  Pages: 3378-3380
- NAID
  130004597226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611010
[Journal Article] Transformation of cytosine to uracil in single-stranded DNA via theiroxime sulfonates.2010
- Author(s)
  Oka, Y.; Takei, F.; Nakatani, K.
- Journal Title
  
  Chem.Commun.
  
  Volume: 46 Pages: 3378-3380
- NAID
  130004597226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611010
[Journal Article] Recognition of Mismatched Base Pairs in DNA2009
- Author(s)
  Nakatani, K.
- Journal Title
  
  Bull.Chem.Soc.Jpn.(総説) 82
  
  Pages: 1055-1069
- NAID
  10025321391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoswitchable Unsymmetrical Ligand for DNA Hetero-Mismatches2009
- Author(s)
  Dohno, C.; Yamamoto, T.; Nakatani, K.
- Journal Title
  
  Eur. J. Org. Chem.
  
  Pages: 4051-4058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Small molecule affecting the replication of trinucleotide repeat d(GAA)n2009
- Author(s)
  He, H.; Hagihara, M.; Nakatani, K.
- Journal Title
  
  Chem.Eur.J. 15
  
  Pages: 10641-10648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] RNA Aptamers That Reversibly Bind Photoresponsive Azobenzene Containing Peptides2009
- Author(s)
  Hayashi G.; Hagihara M.; Nakatani K.
- Journal Title
  
  Chem. Eur. J. 15
  
  Pages: 424-432
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Secondary Structure-Inducible Ligand Fluorescence Coupled with PCR2009
- Author(s)
  Takei, F., Igarashi, M., Hagihara, M., Oka, Y., Soya, Y., Nakatani, K.
- Journal Title
  
  Angew.Chem.Int.Ed. 48
  
  Pages: 7822-7824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611010
[Journal Article] Small Molecule Affecting the Replication of Trinucleotide Repeat d(GAA)n.2009
- Author(s)
  Hanging He, Masaki Hagihara, Kazuhiko Nakatani
- Journal Title
  
  Chemistry-A European Journal 15巻
  
  Pages: 10641-10648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] RNA Aptamers That Reversibly Bind Photoresponsive Azobenzene-Containing Peptides2009
- Author(s)
  Hayashi, G.; Hagihara, M.; Nakatani, K.
- Journal Title
  
  Chem.Eur.J. 15
  
  Pages: 424-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] The Effect of Linker Length on Binding Affinity of a Photoswitchable Molecular Glue for DNA2009
- Author(s)
  Dohno, C.; Uno, S.; Sakai, S.; Oku, M.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 17 Pages: 2536-2543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Photoswitchable Unsymmetrical Ligand for DNA Hetero-Mismatches2009
- Author(s)
  Dohno, C.; Yamamoto, T.; Nakatani, K.
- Journal Title
  
  Eur.J.Org.Chem.
  
  Pages: 4051-4058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Secondary Structure-Inducible Ligand Fluorescence Coupled with PCR2009
- Author(s)
  Takei, F.; Igarashi, M.; Hagihara, M.; Oka, Y.; Soya, Y.; Nakatani, K.
- Journal Title
  
  Angew.Chem.Int.Ed. 48
  
  Pages: 7822-7824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Secondary Structure-Inducible Ligand Fluorescence Coupled with PCR2009
- Author(s)
  Fumie Takei, Masako Igarashi, Masaki Hagihara, Yoshimi Oka, Yoehihiro Soya, Kazuhiko Nakatani
- Journal Title
  
  Angewandte Chemie International Edition 48巻
  
  Pages: 7822-7824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Synthesis and Reaction of DNA Oligomers Containing Modified Cytosines Related to Bisulfite Sequencing2009
- Author(s)
  Oka, Y., Peng, T., Takei, F., Nakatani, K.
- Journal Title
  
  Org.Lett. 11
  
  Pages: 1377-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611010
[Journal Article] A Light-Driven, Supramolecular Optical Switch2009
- Author(s)
  Uno, S.; Dohno, C.; Bittermann, H.; Malinovskii, V.L.; Haner, R.; Nakatani, K.
- Journal Title
  
  Angew.Chem.Int.Ed. 48
  
  Pages: 7362-7365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] A Light-Driven, Supramolecular Optical Switch2009
- Author(s)
  Uno, S.; Dohno, C.; Bittermann, H.; Malinovskii, V. L.; Haner, R.; Nakatani, K.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 48 Pages: 7362-7365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] DNA Labeling by Ligand Inducible Secondary Structure2008
- Author(s)
  Peng T.; He H.; Hagihara M.; Nakatani K.
- Journal Title
  
  ChemBioChem 9
  
  Pages: 1893-1897
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoswitchable Molecular Glue for DNA2007
- Author(s)
  Dohno C.; Uno S.; Nakatani K.
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 11898-11899
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Allele Specific C-bulge Probes with One Unique Fluorescent Molecule Discriminate the Single Nucleotide Difference in DNA2007
- Author(s)
  F., Takei, H., Suda, M., Hagihara, J., Zhang, A., Kobori, K., Nakatani
- Journal Title
  
  Chem. -Eur. J 13
  
  Pages: 4452-4457
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Journal Article] Allele Specific C-bulge Probes with One Unique Fluorescent Molecule Discriminate the Single Nucleotide Difference in DNA2007
- Author(s)
  F. Takei, H. Suda, M. Hagihara, J. Zhang, A. Kobori, K. Nakatani
- Journal Title
  
  Chem. -Eur. J. 13
  
  Pages: 4452-4457
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18550071
[Journal Article] Photoswichable Molecular Glue for DNA2007
- Author(s)
  Dohno, C., Uno, S., Nakatani, K
- Journal Title
  
  J. Am. Chem. Soc 129
  
  Pages: 11898-11899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Emission of characteristic fluorescence from the ligand-cytosine complex in U_A/ACU bulged RNA duplex2007
- Author(s)
  J. Zhang, F. Takei, K. Nakatani
- Journal Title
  
  Bioorganic and Medical chemistry 15
  
  Pages: 4813-4817
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18550071
[Journal Article] Photoswitchable Molecular Glue for DNA2007
- Author(s)
  Dohno, C.; Uno, S.; Nakatani
- Journal Title
  
  K.J.Am.Chem.Soc. 129
  
  Pages: 11898-11899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Allele Specific C-bulge Probes with One Unique Fluorescent Molecule Discriminate the Single Nucleotide Differencein DNA2007
- Author(s)
  F. Takei, H. Suda, M. Hagihara, J. Zhang, A. Kobori, K. Nakatani
- Journal Title
  
  Chem.-Eur. J. 13
  
  Pages: 4452-4457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18550071
[Journal Article] Emission of characteristic fluorescence from the ligand-cytosine complex in U_A/ACU bulged RNA duplex2007
- Author(s)
  J., Zhang, F., Takei, K., Nakatani
- Journal Title
  
  Bioorganic and Medical chemistry 15
  
  Pages: 4813-4817
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Journal Article] Detection of L-DNA-Tagged PCR Products by Surface Plasmon Resonance Imaging2007
- Author(s)
  Hayashi, G., Hagihara, M., Kobori, A., Nakatani,K.
- Journal Title
  
  ChemBioChem 8
  
  Pages: 169-169
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoregulation of a Peptide RNA Interaction on a Gold Surface2007
- Author(s)
  Hayashi G.; Hagihara M.; Dohno C.; Nakatani K.
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 8678-8679
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoregulation of a Peptide-RNA Interaction on a Gold Surface2007
- Author(s)
  Hayashi, G., Hagihara, M., Dohno, C., Nakatani, K.
- Journal Title
  
  J. Am. Chem. Soc 129
  
  Pages: 8678-8679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoregulation of a Peptide-RNA Interaction on a Gold Surface2007
- Author(s)
  Hayashi, G.; Hagihara, M.; Dohno, C.; Nakatani, K.
- Journal Title
  
  J.Am.Chem.Soc. 129
  
  Pages: 8678-8679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Evaluation of mismatch-binding ligands as inhibitors for Rev-RRE interaction2006
- Author(s)
  Nakatani, K., Horie, S., Goto, Y., Kobori, A., Hagihara,S.
- Journal Title
  
  Bioorg.Med.Chem. 14
  
  Pages: 5384-5384
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Mismatch binding ligands function as molecular glue for DNA2006
- Author(s)
  Peng, T., Dohno, C., Nakatani,K
- Journal Title
  
  Angew.Chem.Int.Ed. 45
  
  Pages: 5623-5623
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Small-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide repeats2005
- Author(s)
  K.Nakatani, C.Kojima et al.
- Journal Title
  
  Nature Chemical Biology 1.1
  
  Pages: 43-43
- Data Source
  KAKENHI-PROJECT-16650084
[Journal Article] A new ligand binding to G-G mismatch having improved thermal and alkaline stability2005
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 15
  
  Pages: 259-262
- Data Source
  KAKENHI-PROJECT-16650084
[Journal Article] A new ligand binding to G-G mismatch having improved thermal and alkaline stability2005
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 15
  
  Pages: 259-262
- Data Source
  KAKENHI-PROJECT-16023234
[Journal Article] Small-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide repeats2005
- Author(s)
  K.Nakatani, C.Kojima et al.
- Journal Title
  
  Nature Chemical Biology 1.1
  
  Pages: 43-43
- Data Source
  KAKENHI-PROJECT-17019039
[Journal Article] A new ligand binding to G-G mismatch having improved thermal and alkaline stability2005
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 15
  
  Pages: 259-262
- Data Source
  KAKENHI-PROJECT-15201042
[Journal Article] Small-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide repeats2005
- Author(s)
  K.Nakatani, C.Kojima et al.
- Journal Title
  
  Nature Chemical Biology 1・1
  
  Pages: 43-43
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15201042
[Journal Article] Small-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide repeats,2005
- Author(s)
  K.Nakatani, C.Kojima et al.
- Journal Title
  
  Nature Chemical Biology 1(1)
  
  Pages: 43-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201042
[Journal Article] A new ligand binding to G-G mismatch having improved thermal and alkaline stability2005
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 15
  
  Pages: 259-262
- Data Source
  KAKENHI-PROJECT-16012231
[Journal Article] Solvent Effects on the Suppression of Oxidative Decomposition of Guanine by Phenyl Group Attachment in DNA2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Journal of Physical Chemistry, B 108
  
  Pages: 7500-7505
- Data Source
  KAKENHI-PROJECT-15201042
[Journal Article] Highly Sensitive Detection of GG Mismatched DNA by Surfaces Immobilized Naphthyridine Dimer through Poly(ethylene oxide) Linkers2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 1105-1108
- Data Source
  KAKENHI-PROJECT-16023234
[Journal Article] The binding of Guanine-Guanine Mismatched DNA to Naphthyridine Dimer Immobilized Sensor Surfaces : Kinetic Aspects2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry 12
  
  Pages: 3117-3123
- Data Source
  KAKENHI-PROJECT-16012231
[Journal Article] 2-Ureidoquinoline : a useful molecular element for stabilizing single cytosine ant thymine bulges2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 3431-3433
- Data Source
  KAKENHI-PROJECT-16650084
[Journal Article] Highly Sensitive Detection of GG Mismatched DNA by Surfaces Immobilized Naphthyridine Dimer through Poly(ethylene oxide) Linkers2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 1105-1108
- Data Source
  KAKENHI-PROJECT-16650084
[Journal Article] 2-Ureidoquinoline : a useful molecular element for stabilizing single cytosine ant thymine bulges2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 3431-3433
- Data Source
  KAKENHI-PROJECT-16012231
[Journal Article] The binding of Guanine-Guanine Mismatched DNA to Naphthyridine Dimer Immobilized Sensor Surfaces : Kinetic Aspects2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry 12
  
  Pages: 3117-3123
- Data Source
  KAKENHI-PROJECT-16023234
[Journal Article] The binding of Guanine-Guanine Mismatched DNA to Naphthyridine Dimer Immobilized Sensor Surfaces Kinetic Aspects2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry 12
  
  Pages: 3117-3123
- Data Source
  KAKENHI-PROJECT-16650084
[Journal Article] Solvent Effects on the Suppression of Oxidative Decomposition of Guanine by Phenyl Group Attachment in DNA2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Journal of Physical Chemistry, B 108
  
  Pages: 7500-7505
- Data Source
  KAKENHI-PROJECT-16012231
[Journal Article] Highly Sensitive Detection of GG Mismatched DNA by Surfaces Immobilized Naphthyridine Dimer through Poly (ethylene oxide) Linkers2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 1105-1108
- Data Source
  KAKENHI-PROJECT-15201042
[Journal Article] The binding of Guanine-Guanine Mismatched DNA to Naphthyridine Dimer Immobilized Sensor Surfaces : Kinetic Aspects2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry 12
  
  Pages: 3117-3123
- Data Source
  KAKENHI-PROJECT-15201042
[Journal Article] Highly Sensitive Detection of GG Mismatched DNA by Surfaces Immobilized Naphthyridine Dimer through Poly(ethylene oxide) Linkers2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 1105-1108
- Data Source
  KAKENHI-PROJECT-16012231
[Journal Article] Solvent Effects on the Suppression of Oxidative Decomposition of Guanine by Phenyl Group Attachment in DNA2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Journal of Physical Chemistry, B 108
  
  Pages: 7500-7505
- Data Source
  KAKENHI-PROJECT-16023234
[Journal Article] Solvent Effects on the Suppression of Oxidative Decomposition of Guanine by Phenyl Group Attachment in DNA2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Journal of Physical Chemistry, B 108
  
  Pages: 7500-7505
- Data Source
  KAKENHI-PROJECT-16650084
[Journal Article] 2-Ureidoquinoline : a useful molecular element for stabilizing single cytosine ant thymine bulges2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 3431-3433
- Data Source
  KAKENHI-PROJECT-15201042
[Journal Article] 2-Ureidoquinoline : a useful molecular element for stabilizing single cytosine ant thymine bulges2004
- Author(s)
  中谷和彦ほか
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 3431-3433
- Data Source
  KAKENHI-PROJECT-16023234
[Journal Article] Transformation of cytosine to uracil in single-stranded DNA via their oxime sulfonates
- Author(s)
  Oka, Y., Takei, F., Nakatani, K.
- Journal Title
  
  Chem.Commun. (In press)
- NAID
  130004597226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611010
[Journal Article] Bidirectional Control of Gold Nanoparticle Assembly by Turning On and Off DNA Hybridization with Thermally Degradable Molecular Glue
- Author(s)
  Peng, T., Dohno, C., Nakatani, K.
- Journal Title
  
  ChemBioChem (in press)
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Allele Specific C-bulge Probes with One Unique Fluorescent Molecule Discriminate the Single Nucleotide Difference in DNA
- Author(s)
  F.Takei, H.Suda, M.Hagihara, J.Zhang, A.Kobori, K.Nakatani
- Journal Title
  
  Chem.- Eur. J. (In press)
- Data Source
  KAKENHI-PROJECT-18550071
[Journal Article] Allele Specific C-Bulge Probes with One Unique Fluorescent Molecule Discriminate the Single Nucleotide Polymorphism in DNA
- Author(s)
  Takei, F., Suda, H., Hagihara, M., Zhang, J., Kobori, A., Nakatani,K.
- Journal Title
  
  Chem.Eur.J. (in press)
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Exploiting Small Molecule Binding to DNA for the Detection of Single-Nucleotide Mismatches and Their Base Environment
- Author(s)
  Li, X., Song, H., Nakatani, K., Kraatz, H.-B.
- Journal Title
  
  Anal.Chem. (in press)
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Control of DNA hybridization by photoswitchable molecular glue.
- Author(s)
  Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem.Soc.Rev.(総説) in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Synthesis and Reaction of DNA Oligomers Containing Modified Cytosines Related to Bisulfite Sequencing
- Author(s)
  Yoshimi Oka, Tao Peng, Fumie Takei, Kazuhiko Nakatani
- Journal Title
  
  ORGANIC LETTERS (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611010
[Patent] PCR法およびPCRキット2015
- Inventor(s)
  中谷和彦、坂本史惠
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-08-24
- Overseas
- Data Source
  KAKENHI-PROJECT-26000007
[Patent] PCR法およびPCRキット2014
- Inventor(s)
  中谷和彦、武井史恵
- Industrial Property Rights Holder
  中谷和彦、武井史恵
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-169900
- Filing Date
  2014-08-22
- Data Source
  KAKENHI-PROJECT-24310165
[Patent] 一塩基多型を検出する方法および一塩基多型を検出するための試薬キット2010
- Inventor(s)
  中谷和彦、武井史恵、萩原正規
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Number
  2010-054658
- Filing Date
  2010-03-11
- Data Source
  KAKENHI-PROJECT-18105006
[Patent] 一塩基多型を検出する方法および一塩基多型を検出するための試薬キット2010
- Inventor(s)
  中谷和彦、武井史恵、萩原正規
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Number
  2010-054658
- Filing Date
  2010-03-11
- Data Source
  KAKENHI-PROJECT-20611010
[Patent] 核酸と被験物質との結合親和性を測定するための組成物及びその利用2008
- Inventor(s)
  中谷和彦、張錦華、梅本詩織、笹岡眞一、和崎隆博
- Industrial Property Rights Holder
  大阪大学、日東化成株式会社
- Industrial Property Number
  2009-519347
- Filing Date
  2008-07-30
- Data Source
  KAKENHI-PROJECT-18105006
[Patent] 核酸の増幅反応に用いるプライマー5'末端に結合して用いるDNA断片及びその利用2006
- Inventor(s)
  中谷和彦, 武井史恵, 萩原正規
- Industrial Property Number
  2006-238299
- Filing Date
  2006-09-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Patent] DNA二本鎖形成制御2006
- Inventor(s)
  中谷ほか
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2006-06-12
- Data Source
  KAKENHI-PROJECT-18105006
[Patent] DNA二本鎖形成制御2006
- Inventor(s)
  中谷和彦、Peng Tao、堂野主税
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Number
  2006-162265
- Filing Date
  2006-06-12
- Data Source
  KAKENHI-PROJECT-18105006
[Patent] 核酸の増幅反応に用いる繰り返し配列結合プライマ-及びその利用
- Inventor(s)
  中谷和彦、Peng Tao、萩原正規
- Industrial Property Rights Holder
  大阪大学
- Data Source
  KAKENHI-PROJECT-18105006
[Patent] Methods of Treating Diseases Associated with Repeat Instability
- Inventor(s)
  中谷和彦、中森雅之、Christopher Pearson
- Industrial Property Rights Holder
  国立大学法人大阪大学、ザ・ホスピタル・フォー・シック・チルドレン
- Overseas
- Data Source
  KAKENHI-PROJECT-26000007
[Patent] 核酸の増幅反応に用いるプライマ-の5'末端に結合して用いるDNA 断片およびその利用
- Inventor(s)
  中谷和彦、武井史恵、萩原正規
- Industrial Property Rights Holder
  大阪大学
- Data Source
  KAKENHI-PROJECT-18105006
[Presentation] Controlling -1 ribosomal frameshifting by small molecules in cells2020
- Author(s)
  Asako Murata, Saki Matsumoto, Neva Caliskan, Marina V. Rodnina, Kazuhiko Nakatani
- Organizer
  The 23rd SANKEN INTERNATIONAL SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 2-アミノ-1, 8-ナフチリジン二量体の結合位置異性体の合成と核酸との結合評価2020
- Author(s)
  桑原聡己、Das Bimolendu、中谷和彦
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 光異性化特性を向上させた新規光応答性核酸結合分子の開発2020
- Author(s)
  小林笙太朗、堂野主税、中谷和彦
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Assembly of ruthenium complexes on dsDNA using mismatch binding ligand2020
- Author(s)
  Lu Ni, Takeshi Yamada, Kazuhiko Nakatani
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Structural analysis and functionalization of naphthyridine dimer derivatives bound to CGG repeats2020
- Author(s)
  Takeshi Yamada, Shuhei Sakurabayashi, Kyoko Huruitab, Chojiro Kojima, Kazuhiko Nakatani
- Organizer
  The 23rd SANKEN INTERNATIONAL SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Recognition of Pyrimidine Based Asymmetric Internal Loops in Duplex DNA and RNA by ANP77, a Three-Carbon Atom Linked 2-Amino-1, 8-naphthyridine Dimer2020
- Author(s)
  Bimolendu Das, Kazuhiko Nakatani
- Organizer
  The 23rd SANKEN INTERNATIONAL SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and nucleic acid binding property of a series of quinoxaline-2, 3-dione derivatives2020
- Author(s)
  Zilu Xing, Tomonori Shibata, Kazuhiko Nakatani
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Dicer切断反応を指標としたRNA結合分子標的配列の網羅的解析2020
- Author(s)
  高島裕介、村田亜沙子、中谷和彦
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and the properties of NA Dimer2020
- Author(s)
  Chen Qingwen, Yamada Takeshi, Murata Asako, Nakatani Kazuhiko
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and properties of 13C-labeled naphthyridine derivative2020
- Author(s)
  Shuhei Sakurabayashi, Takeshi Yamada, Gota Kawai, Kazuhiko Nakatani
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small Molecules targeting Repeat Sequences causing Neurological Disorders2019
- Author(s)
  Kazuhiko Nakatani
- Organizer
  The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] ANP77 : A Three-carbon Atom Linked 2-Amino-1, 8-naphthyridine Dimer that Recognizes Cytosine Rich Bulge-mismatched Sequences of Duplex DNA and RNA2019
- Author(s)
  Bimolendu Das, Kazuhiko Nakatani
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small Molecules targeting Repeat Sequences causing Neurological Disorders2019
- Author(s)
  中谷和彦
- Organizer
  IUPAC International Symposium on Bioorganic Chemistry (ISBOC-12)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22254
[Presentation] RNA binding small molecule that mitigates disease phenotype in spinocerebellar ataxia type 312019
- Author(s)
  Tomonori Shibata, Konami Nagano, Morio Ueyama, Yoshitaka Nagai, Kinya Ishikawa, Gota Kawai, and Kazuhiko Nakatani
- Organizer
  The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small Molecules targeting Repeat Sequences causing Neurological Disorders2019
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Symposium on Nucleic Acids Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small Molecules targeting Trinucleotide Repeat Sequences causing Neurological Disorders2019
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Trends in Nucleic Acid
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 核酸標的低分子創薬に向けて : 何から始める? 何が足りない?2019
- Author(s)
  中谷和彦
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 脊髄小脳変性症31型を標的とするRNA結合性低分子2019
- Author(s)
  柴田知範、長野来南、上山盛夫、永井義隆、石川欽也、河合剛太、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] GGCCCCリピート結合分子N, N’-ジヘテロアリールグアニジン誘導体の合成及び結合評価2019
- Author(s)
  村上英太郎、柴田知範、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] d(CTG)リピートへ結合する新規分子の合成及び結合評価2019
- Author(s)
  岡本竜政、中谷和彦
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] XGGリピートDNA中のピリミジン塩基を選択的に酸化するリガンドの開発2019
- Author(s)
  八木勇樹、山田剛史、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of RNA cleaving activity of hammerhead ribozyme by a synthetic RNA binding molecule2019
- Author(s)
  Chikara Dohno, Maki Kimura, Kazuhiko Nakatani
- Organizer
  The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Dicer切断を阻害するRNA結合分子標的配列の網羅的解析2019
- Author(s)
  高島祐介、村田亜沙子、中谷和彦
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] The methylation effect for binding of dimeric 2-amino-1, 8-naphthyridine derivatives to CGG/CGG triad in DNA2019
- Author(s)
  Takeshi Yamada, Shuhei Sakurabayashi, Kazuhiko Nakatani
- Organizer
  The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Computer-aided molecular design for DNA bulge recognition ligands by order-N elongation method2019
- Author(s)
  Yuuichi Orimoto, Anna Pomogaeva, Keisuke Hisama, Ayaka Yano, Koichi Miyagawa, Kazuhiko Nakatani, Yuriko Aoki
- Organizer
  第46回国際核酸化学シンポジウム日本核酸化学会第3回年会(ISNAC2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] DNAミスマッチ部位に結合する小分子に関する分子動力学および量子化学計算による研究2019
- Author(s)
  宮川晃一, 庄司光男, 中谷和彦, 重田育照, 山口兆
- Organizer
  第13回分子科学討論会
- Data Source
  KAKENHI-PROJECT-19K22254
[Presentation] Toward site selective modification of pyrimidine bases flipped out by naphthyridine cabamate dimer binding.2019
- Author(s)
  Yuki Yagi, Takeshi Yamada, Kazuhiko Nakatani
- Organizer
  JSPS日中韓フォーサイト事業アジア化学プローブ研究拠点第3回A3若手研究者ミーティング
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 7位修飾ナフチリジンカルバメートダイマーの合成と結合特性2019
- Author(s)
  櫻林修平、山田剛史、中谷和彦
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Novel Design Strategy of DNA-Artificial Nucleic Acid Chimeras Toward Enhancement of RNase H Cleavage Activities2019
- Author(s)
  Masahito Inagaki, Akira Yano, Seiya Ishizawa, Masaki Nishijima, Yasuyuki Arakil, Satoru Ishibashi, Asako Yamayoshi, Kazuhiko Nakatani, Takanori Yokota, Takehiko Wada
- Organizer
  第46回国際核酸化学シンポジウム日本核酸化学会第3回年会(ISNAC2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] ピペラジン骨格を有する新規ナフチリジン誘導体の創成とRNAとの結合評価2019
- Author(s)
  小林笙太朗、廬藝歡、堂野主税、中谷和彦
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Kinetic analysis of the inhibitory effect of BzDANP on Dicer cleavage of pre-miR-1362019
- Author(s)
  Asako Murata, Takahiro Otabe, Konami Nagano, Gota Kawai, Ayako Sugai, Kazuhiko Nakatani
- Organizer
  The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats2019
- Author(s)
  Sanjukta Mukherjee, Leszek Blaszczyk, Wojciech Rypniewski, Christoph Falschlunger, Ronald Micura, Asako Murata, Chikara Dohno, Kazuhiko Nakatani, Agnieszka Kiliszek
- Organizer
  The 24th Annual Meeting of the RNA Society (RNA 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Modulation of ribozyme activity by conformational changes induced by a synthetic RNA binding molecule2019
- Author(s)
  Chikara Dohno, Maki Kimura, Kazuhiko Nakatani
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Recognition of bulge-mismatched dsDNA's by a three-carbon atom linked 2-amino-1, 8-naphthyridine dimer2019
- Author(s)
  Das Bimolendu, Kazuhiko Nakatani
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] N, N' -ジヘテロアリールグアニジン誘導体の合成とGGCCCCリピートDNAへの結合評価2019
- Author(s)
  村上英太郎、柴田知範、中谷和彦
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small Molecules targeting Repeat Sequences causing Neurological Disorders2019
- Author(s)
  Kazuhiko Nakatani
- Organizer
  7th Symposium RIKEN - Max Planck Joint Research Center for Systems Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] DNAミスマッチ部位に結合する小分子に関する分子動力学および量子化学計算による研究2019
- Author(s)
  宮川晃一, 庄司光男, 中谷和彦, 重田育照, 山口兆
- Organizer
  第13回分子科学討論会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 配列選択的ピリミジン塩基の酸化を指向した、ナフチリジンカルバメートダイマー誘導体の合成とその評価2019
- Author(s)
  八木勇樹、山田剛史、中谷和彦
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Exploration of RNA sequences in pre-miRNA affecting the efficiency of Dicer cleavage reactions by the small molecules binding2019
- Author(s)
  Yusuke Takashima, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 24th Annual Meeting of the RNA Society (RNA 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small Molecules targeting Repeat Sequences causing Neurological Disorders2019
- Author(s)
  Kazuhiko Nakatani
- Organizer
  10th ISAJ Annual Symposium 2019
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 核酸標的低分子創薬を支えるゲノム化学2019
- Author(s)
  中谷和彦
- Organizer
  2019 前期有機合成化学講習会
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small molecules targeting DNA and RNA repeats as potential drugs for neurological disorders2019
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Indo-Japan (NCBS/InStem-Osaka) Meeting : Interfacing chemistry and biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Dimeric Form of 1, 3-diaminoisoquinoline Derivatives Improved Alternative Splicing in Myotonic Dystrophy Type I Mouse Model2019
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Asian 3 Roundtable on Nucleic Acids (A3RONA 2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small Molecules targeting Repeat Sequences causing Neurological Disorders2019
- Author(s)
  Kazuhiko Nakatani
- Organizer
  IUPAC International Symposium on Bioorganic Chemistry (ISBOC-12)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] リピートDNA、RNAに結合する低分子化合物による神経変性疾患治療への試み2019
- Author(s)
  中谷和彦
- Organizer
  第1回医学系研究科・産業科学研究所懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Rational design of CUG repeat binging molecule targeting Myotonic Dystrophy type 12018
- Author(s)
  Jun Matsumoto, Jinxing Li, Asako Murata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  日本ケミカルバイオロジー学会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] RNAを標的とした低分子創成の実際2018
- Author(s)
  中谷和彦
- Organizer
  第399回情報計算化学生物学会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Fluorescent molecules binding to DNA bulges and mismatches : toward application for the practical use2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Fluorescent Biomolecules and their Building Blocks (FB3)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of RNA structure and function by small organic molecules2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Seoul National University Korea seminar,
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 核酸塩基認識を指向したインドール誘導体の合成及び評価2018
- Author(s)
  南凌、堂野主税、中谷和彦
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of novel miRNA detection system using PCR with C-Bulge probe and fluorescence molecule2018
- Author(s)
  Fumie Takei, Misaki Akiyama, Asako Murata,Akiko Sugai, Kazuhiko Nakatani, Ichiro Yamashita
- Organizer
  第45回国際核酸化学シンポジウム（ISNAC 2018）/日本核酸化学会第2回年会　ISNAC2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14027
[Presentation] Repeat-Assisted Dimerization of Thiol Modified Mismatch Binding Ligand2018
- Author(s)
  Takeshi Yamada, Kazuhiko Nakatani
- Organizer
  International Roundtable of Nucleosides, Nucleotides, and Nucleic Acids (IRT)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Repeat DNA assisted dimerization of mismatch binding molecules through intermolecular disulfide formation2018
- Author(s)
  Takeshi Yamada, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] リピートRNA結合化合物によるリピート病の制御への試み2018
- Author(s)
  中谷和彦
- Organizer
  第59回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] ADDA水素結合面を有する含窒素芳香族グアニジンの合成及び核酸との結合評価2018
- Author(s)
  村上英太郎、柴田知範、中谷和彦
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Targeting DNA- and RNA-repeats responsible for Neurological Disorders by Small Molecules2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  18th International Symposium at TMIMS on Structured Nucleic Acids
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] RNAを標的とした低分子の創成～本当に可能ですよ～2018
- Author(s)
  中谷和彦
- Organizer
  日経バイオテクプロフェッショナルセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and evaluation of ligands binding to C9orf72 GGCCCC repeat DNA related to ALS/FTD2018
- Author(s)
  Eitaro Murakami, Tomonori Shibata, Kazuhiko Nakatani
- Organizer
  The Third A3 Roundtable Meeting on Chemical Probe Research Hub
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Naphthyridine tetramer as a bivalent ligand targeting DNA expanded GGGGCC sequences2018
- Author(s)
  Y. Lu, C. Dohno, K. Nakatani
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Targeting DNA and RNA repeats responsible for Neurological Disorders by Small Organic Molecules2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  The 3rd A3 Roundtable Meeting on Chemical Probe Research Hub
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Targeting DNA and RNA repeats responsible for neurological disorders by small organic molecules2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  The Weizmann Institute of Science Israel, seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] A novel miRNA detection system using PCR with DNA probe and fluorescence molecule.2018
- Author(s)
  Fumie Takei, Misaki Akiyama, Asako Murata,Akiko Sugai, Kazuhiko Nakatani, Ichiro Yamashita
- Organizer
  IWSBN2018
- Data Source
  KAKENHI-PROJECT-16K14027
[Presentation] 分子動力学シミュレーションによる核酸のミスマッチ部位に結合する小分子に関する研究2018
- Author(s)
  宮川晃一, 庄司光男, 中谷和彦, 重田育照, 山口兆
- Organizer
  第12回分子科学討論会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Functional Regulation of Epigenetic DNA Modifications using Photoreactive Oligonucleotides2018
- Author(s)
  Asako Yamayoshi, Takayuki Shibata, Yui Sakai, Takeshi Yamada, Tsuyoshi Yamamoto, Takehiko Wada, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and evaluation of ligands binding to C9orf72 GGCCCC repeat DNA related to ALS/FTD2018
- Author(s)
  Eitaro Murakami, Tomonori Shibata, Kazuhiko Nakatani
- Organizer
  JSPS日中韓フォーサイト事業アジア化学プローブ研究拠点第2回A3若手研究者ミーティング
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Recognition of DNA GGGGCC repeats by novel naphthyridine tetramer2018
- Author(s)
  Yihuan Lu, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of Isoquinoline Ligand Binding to r(CUG) Repeats2018
- Author(s)
  Jun Matsumoto, Jinxing Li, Masayuki Nakamori, Asako Murata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Targeting Trinucleotide Repeat Sequences by Small Organic Molecules2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Trends in Nucleic Acid
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small molecule induced CAG/CTG repeat contraction during PCR : Repeat length dependency2018
- Author(s)
  N. Binti Mohd Zaifuddin, C. Dohno, K. Nakatani
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 1, 3-Di (quinolin-2-y1) guanidine binding to C9orf72 GGCCCC repeat DNA in ALS/FTD2018
- Author(s)
  Eitaro Murakami, Tomonori Shibata, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of RNA structure and function by small organic molecules2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Sungkyunkwan University Suwon, Korea, seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Fluorescent Ligand binding to DNA and Its Potential Application in PCR and Sensing Disease Related Repeat Sequences2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  3rd International Caparica Conference on Chromogenic and Emissive Materials (IC3EM)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Binding Studies of a Three Carbon Atom Linked 2-amino-1, 8- Naphthyridine Dimer with Bulge-Mismatch DNA2018
- Author(s)
  B. Das, K. Nakatani
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Rationally engineered ribozyme activatable by ligand induced restoration of tertiary structure2018
- Author(s)
  Chikara Dohno, Maki Kimura, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small molecule interactions with DNA and RNA, and their application for sensing Hairpin-Primer PCR2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Meeting at National Chiao Tung University
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 2-アミノ-1, 8-ナフチリジン3量体の合成およびそのDNA結合特性の解析2018
- Author(s)
  八木勇樹、相川春夫、中谷和彦
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthetic small molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting2018
- Author(s)
  Asako Murata, Saki Matsumoto, Neva Caliskan, Marina V. Rodnina, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 金属に配位可能な側鎖をもつアミノ酸で修飾したミスマッチDNA結合性小分子の合成と性質2018
- Author(s)
  三木翔太、山田剛史、中谷和彦
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of Isoquinoline Ligand Binding to r(CUG) Repeats2018
- Author(s)
  Jun Matsumoto, Jinxing Li, Asako Murata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  International Roundtable of Nucleosides, Nucleotides, and Nucleic Acids (IRT)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Targeting DNA and RNA repeats responsible for neurological disorders by small organic molecules2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Faculty of Science, The Hebrew University of Jerusalem Israel, seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of RNA structure and function by small organic molecules2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Seoul National University Korea seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] DNA、RNAの特徴的な配列を標的とする低分子創薬の現状と展望2018
- Author(s)
  中谷和彦
- Organizer
  ヒューマンサイエンス振興財団ヒアリング
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Targeting Spinocerebellar ataxia 31 (SCA31) by Small Molecules2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  2018 Bilateral Symposium Academia Sinica & Osaka University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of RNA structure and function by small organic molecules2018
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Dankook University Yongin-si, Korea seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] A new idea of PCR progress monitoring by Electrochemical Impedance Spectroscopy (EIS): combination of ligands and hairpin primer2017
- Author(s)
  Huanwen Han, Norhayati Binti Sabani, Kazuyuki Nobusawa, Fumie Takei, Kazuhiko Nakatani, Ichiro Yamashita
- Organizer
  IWSBN2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14027
[Presentation] 治らない遺伝子疾患を標的にした低分子創成研究2017
- Author(s)
  中谷和彦
- Organizer
  第43回反応と合成の進歩シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] RNAをターゲットとする低分子創薬に向けて2017
- Author(s)
  中谷和彦
- Organizer
  NPO法人 mRNAターゲット創薬研究機構シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Studies on Small Molecules targeting Repeat Diseases2017
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Asian Chemical Biology Initiative, 2017 Ulaanbaatar Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 1型筋強直性ジストロフィーに見られるMBNL1-CUGexp 相互作用における新規イソキノリン誘導体の阻害効果2017
- Author(s)
  松本惇、中谷和彦
- Organizer
  第40回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Cross-linking behavior of psoralen-conjugated oligonucleotides toward epigenetic DNA modifications2017
- Author(s)
  A. Yamayoshi, T. Yamada, Y. Araki, A. Murakami, T. Wada, K. Nakatani, H. Sugiyama
- Organizer
  ISNAC 2017 (The 44th International Symposium on Nucleic Acids Chemistry)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Novel isoquinoline derivatives that inhibit MBNL1-CUG repeat interaction in Myotonic Dystrophy typel2017
- Author(s)
  J. Matsumoto, J. Li, A. Murata, C. Dohno, K. Nakatani
- Organizer
  ISNAC 2017 (The 44th International Symposium on Nucleic Acids Chemistry)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 疎水性官能基を有するリピートDNA結合リガンドの評価2017
- Author(s)
  山内和明、堂野主税、中谷和彦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應大学、横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and evaluation of small molecules binding to G4C2 DNA repeat2017
- Author(s)
  Yuihuan Lu, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應大学、横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] ランダムペンタペプチド修飾ナフチリジンの合成およびバルジDNAとの結合評価2017
- Author(s)
  伊藤洋志、相川春夫、中谷和彦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應大学、横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Design of ligand for sensing: the combination of hairpin primer DANP ligand.2017
- Author(s)
  Fumie Takei, Misaki Akiyama, Kazuyuki Nobusawa, Norhayati Binti Sabani, Kazuhiko Nakatani, Ichiro Yamashita,
- Organizer
  IWSBN2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14027
[Presentation] Polymerase Chain Reaction (PCR) under low ionic strength2017
- Author(s)
  H. Han, F. Takei, M. Akiyama, K. Nobusawa, N. B. Sabani, K. Nakatani, I. Yamashita
- Organizer
  第64回応用物理学会春季学術講演会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-16K14027
[Presentation] Regulation of -1 Ribosomal Frameshifting by Small Molecules2017
- Author(s)
  Kazuhiko Nakatani
- Organizer
  The 1st Joint Workshop of Nanyang Technological University and Osaka University on Fundamental Science
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small Organic Molecules Regulating RNA Structure and Function #42017
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Asian Chemical Biology Initiative
- Place of Presentation
  Ho Chi Minh City, Vietnam
- Year and Date
  2017-01-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] チミンバルジを標的にしたリガンド設計の量子化学的アプローチ2017
- Author(s)
  矢野綾香、中谷和彦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應大学、横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Toward discovery of molecules regulating nucleic acids structure and function2017
- Author(s)
  Kazuhiko Nakatani
- Organizer
  JSPS Kickoff symposium ZIAM/GBB-ISIR/IPR
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 低分子による核酸構造の認識とその創薬研究への応用2017
- Author(s)
  中谷和彦
- Organizer
  第827回千葉県がんセンター研究所集談会
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CAG/CTG repeat-targeting-ligands induce repeat contraction during PCR amplification2017
- Author(s)
  N. Binti Mohd Zaifuddin, C. Dohno, K. Nakatani
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] PCR primer detection via molecular recognition by surface modified molecular ligand2017
- Author(s)
  Kazuyuki Nobusawa, Fumie Takei, Norhayati Binti Sabani, Huan-wen Han, Ichiro Yamashita, Kazuhiko Nakatani
- Organizer
  9th International Conference on Molecular Electronics and Bioelectronics (M&BE9)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14027
[Presentation] Development of a SNP typing in the low ionic PCR condition2017
- Author(s)
  Fumie Takei, Misaki Akiyama, Kazuyuki Nobusawa, Norhayati Binti Sabani, Huanwen Han, Kazuhiko Nakatani, Ichiro Yamashita
- Organizer
  9th International Conference on Molecular Electronics and Bioelectronics (M&BE9)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14027
[Presentation] Thiol Modified Naphthyridine Carbamate Dimer Accumulated on CGG Repeat DNA2017
- Author(s)
  T. Yamada, S. Miki, K. Nakatani
- Organizer
  ISNAC 2017 (The 44th International Symposium on Nucleic Acids Chemistry)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Targeting Trinucleotide Repeat Sequences by Small Organic Molecules2017
- Author(s)
  Kazuhiko Nakatani
- Organizer
  2nd A3 Roundtable Meeting on Chemical Probe Research Hub
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] A small molecule that target UGGAA pentanucleotide repeats in spinocerebellar ataxia 312017
- Author(s)
  T. Shibata, M. Ueyama ; Y. Nagai, K. Nakatani
- Organizer
  RNA 2017 (The 22nd Annual Meeting of the RNA Society)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Targeting Trinucleotide Repeat Sequences by Small Organic Molecules2017
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Mini-Symposium on Nucleic Acid Chemistry, 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] RNA切断活性をもつミスマッチ結合性リガンドの開発2017
- Author(s)
  三木翔太、山田剛史、中谷和彦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應大学、横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 核酸高次構造を制御するケミカルバイオロジー2017
- Author(s)
  中谷和彦
- Organizer
  日本化学会第97春季年会中長期企画生体高分子を精密に合成し利用するケミカルバイオロジー
- Place of Presentation
  慶応大学、横浜
- Year and Date
  2017-03-16
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 低塩濃度におけるアレル特異的PCR法の開発2017
- Author(s)
  武井史恵，秋山美咲，信澤和幸， Norhayati Binti Sabani, 韓　煥文, 中谷和彦, 山下一郎
- Organizer
  第64回応用物理学会春季学術講演会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-16K14027
[Presentation] Simple screening method for ligands affecting CAG/CTG repeats stability2017
- Author(s)
  Nursakinah Binti Mohd Zaifuddin, Jinxing Li, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應大学、横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Designing small molecules targeting CUG repeats causing Myotonic Dystrophy type 12017
- Author(s)
  J. Li, J. Matsumoto, B. Li-Ping, A. Murata, C. Cohno, K. Nakatani
- Organizer
  RNA 2017 (The 22nd Annual Meeting of the RNA Society)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] A Novel Riboswitch Strategy by Utilize Mismatch Binding Ligand (MBL)2017
- Author(s)
  A. U1' Husna, S. Matsumoto, A. Murata, K. Nakatani
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] The PCR amplification limit under low ionic conditions2017
- Author(s)
  Huan-wen Han,Kazuyuki Nobusawa, Fumie Takei, Norhayati Binti Sabani, Ichiro Yamashita, Kazuhiko Nakatani
- Organizer
  9th International Conference on Molecular Electronics and Bioelectronics (M&BE9)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14027
[Presentation] Targeting Diseases-related Trinucleotide Repeat Sequences by Small Organic Molecules2017
- Author(s)
  Kazuhiko Nakatani
- Organizer
  120th KCS General Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of RNA Secondary Structure and Function2016
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Asian Chemical Biology Initiative 2016 Jakarta Meeting
- Place of Presentation
  Jakarta(Indonesia)
- Year and Date
  2016-01-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and properties of DNA mismatch binding molecules having thiol functional group2016
- Author(s)
  YAMADA, Takeshi : MICHIKAWA, Akiko : NAKATANI, Kazuhiko
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学京田辺キャンパス(京都府・京田辺市)
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CUGリピート結合性リガンドの探索2016
- Author(s)
  松本惇・李金星・中谷和彦
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学京田辺キャンパス(京都府・京田辺市)
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 疎水性官能基を有する新規DNA結合リガンドの合成2016
- Author(s)
  山内和明・堂野主税・中谷和彦
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学京田辺キャンパス(京都府・京田辺市)
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] xpected Research Development : Toward Creation of New Industry by Hairpin-Primer2016
- Author(s)
  Kazuhiko Nakatani
- Organizer
  17th Chitose International Forum on Photonics Science and Technology
- Place of Presentation
  千歳科学技術大学、千歳
- Year and Date
  2016-11-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of small molecules targeting the CUG repeats that cause myotonic dystrophy type 12016
- Author(s)
  Jinxing Li, Jun Matsumoto, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  ISNAC2016
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of Gene Expression by Ligand-Inducible -1 Ribosomal Frameshifting2016
- Author(s)
  Saki Matsumoto、Asako Murata、Kazuhiko Nakatani
- Organizer
  Aptamers in Bordeaux
- Place of Presentation
  University of Bordeaux France
- Year and Date
  2016-06-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 生体分子修飾型ナフチリジンの合成およびDNA, RNAとの結合評価2016
- Author(s)
  伊藤洋志・相川春夫・中谷和彦
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学京田辺キャンパス(京都府・京田辺市)
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] In vitro selection of pre-miR-29a loop mutant against the cyclic mismatch binding ligand (CMBL)2016
- Author(s)
  Sanjukta Mukherjee, Asako Murata, Kazuhiko Nakatani
- Organizer
  ISNAC2016
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 小分子化合物によるマイクロRNA生成阻害の速度論的解析2016
- Author(s)
  小田部尭広、村田亜沙子、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of the allele specific PCR under the low ion　PCR condition,2 Kazuhiko Nakatani,2 Ichiro Yamashita2016
- Author(s)
  F. Takei, M. Akiyama, K. Nobusawa, N. B. Sabani, K. Nakatani, I. Yamashita
- Organizer
  The 43rd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  熊本大学
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14027
[Presentation] 小分子によるRNAの構造と機能制御2016
- Author(s)
  Kazuhiko Nakatani
- Organizer
  有機合成化学協会東北支部春の講演会
- Place of Presentation
  東北大学、仙台
- Year and Date
  2016-05-28
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Binding of amphiphilic DNA to lipid membrane regulated by formation of higher order structures2016
- Author(s)
  Chikara Dohno, Hayato Yamaguchi, Shingo Makishi, Koichi Matsuzaki, Kazuhiko Nakatani
- Organizer
  ISNAC2016
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CAGリピートDNAおよびRNAを標的としたナフチリジンーアザキノロン誘導体の開発と転写および翻訳への阻害効果2016
- Author(s)
  阪田彬裕, 村田亜沙子, 李金星, 松本咲, Li-ping BAI, 堂野主税, 小比賀聡, 中谷和彦
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small molecules regulating DNA and RNA structure and functions2016
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Bilateral Symposium of Genomics Research Center, Academia Sinica and Graduate School of Science, Osaka University
- Place of Presentation
  Osaka, Japan
- Year and Date
  2016-10-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of RNA Secondary Structure and Function2016
- Author(s)
  Kazuhiko Nakatani
- Organizer
  University of Bordeaux-Osaka University, Osaka City University Mini-Symposium on Synthetic Biology
- Place of Presentation
  Osaka University (Osaka, Suita)
- Year and Date
  2016-01-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 低分子による核酸構造と機能の調節2016
- Author(s)
  Kazuhiko Nakatani
- Organizer
  IGERグリーン自然科学レクチャー
- Place of Presentation
  名古屋大学、名古屋
- Year and Date
  2016-06-10
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] へアピン型プローブを使った蛍光増大型PCR法の開発2015
- Author(s)
  武井　史恵・中谷　和彦
- Organizer
  日本化学会第９５春季年会
- Place of Presentation
  千葉
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-24310165
[Presentation] A novel ligand that selectively targets CUG trinucleotide repeats2015
- Author(s)
  Jinxing Li, Jun Mastumoto, Li-Ping Bai, Chikara Dohno, Zhi-Hong Jiang, and Kazuhiko Nakatani
- Organizer
  RNA2015, The 20th Annual Meeting of the RNA Society
- Place of Presentation
  Wisconsin(USA)
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and evaluation of naphthyridine derivatives having amino sugar2015
- Author(s)
  Haruo Aikawa, Yasuyuki Okada, Hiroshi Ito, Kazuhiko Nakatani
- Organizer
  Pacifichem2015
- Place of Presentation
  Hawaii(USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Modulation of DNA/RNA structure and function by Small Synthetic Molecules2015
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Seminar at Department of Prof Marina Rodnina Laboratory, Institute of Physical Biochemistry Max Planck Institute for Biophysical Chemistry
- Place of Presentation
  Göttingen(Germany)
- Year and Date
  2015-09-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of Structure and Function of Nucleic Acids by Small Molecules2015
- Author(s)
  中谷和彦
- Organizer
  2015 IMCE International Symposium
- Place of Presentation
  九州大学
- Year and Date
  2015-01-28
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of Gene Expression by Ligand-Inducible -1 Ribosomal Frameshifting2015
- Author(s)
  Kazuhiko Nakatani
- Organizer
  NEA & ASISAHORSc Joint Symposium on Chemical Biology
- Place of Presentation
  Okinawa Institute of Science and Technology (Okinawa, Onna-Son)
- Year and Date
  2015-11-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Evaluation of Small Molecule Ligands that Bind to GGGGCC Repeats2015
- Author(s)
  Jun Matsumoto, Saki Matsumoto, Chikara Dohno, and Kazuhiko Nakatani
- Organizer
  ISNAC2015
- Place of Presentation
  Egret Himeji (Hyogo, Himeji)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] マイクロRNA前駆体結合分子の探索2015
- Author(s)
  相川春夫、福澄岳雄、原田恭枝、須貝亜矢子、村田亜沙子、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  東北大学川内キャンバス(宮城県・仙台市)
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Sensing small molecules regulating gene expression by modulating RNA secondary structures2015
- Author(s)
  Kazuhiko Nakatani
- Organizer
  3rd Core to Core Program Conference 4th imec Handai International Symposium
- Place of Presentation
  Eindhoven (The Netherlands)
- Year and Date
  2015-06-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] A novel ligand that selectively targets CCG trinucIeotide repeats2015
- Author(s)
  Jinxing Li, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  ISNAC2015
- Place of Presentation
  Egret Himeji (Hyogo, Himeji)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Analysis of binding of naphthyridine-azaquinolone derivatives to CAG repeats RNA2015
- Author(s)
  Akihiro Sakata, Jinxing Li, Hanping He, Asako Murata, Chikara Dohno, Satoshi Obika, Kazuhiko Nakatani
- Organizer
  Pacifichem2015
- Place of Presentation
  Hawaii(USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of Gene Expression by Ligand-Inducible -1 Ribosomal Frameshifting2015
- Author(s)
  Kazuhiko Nakatani
- Organizer
  3rd CRL Forum (第三回資源研フォーラム)
- Place of Presentation
  東京工業大学(東京都・目黒区)
- Year and Date
  2015-10-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Molecular Design of Mismatch Binding Ligands, Chemistry Concept and Biological Application2015
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Seminar at IBCH, Polish Academy of Science
- Place of Presentation
  Poznan(Poland)
- Year and Date
  2015-09-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and Binding Property of Naphthyridine-Azaquinolone Derivatives Targeting (CAG)n Repeat RNA2015
- Author(s)
  Akihiro Sakata, Jinxing Li, Hanping He, Li-ping Bai, Asako Murata, Chikara Dohno, Satoshi Obika, and Kazuhiko Nakatani
- Organizer
  ISNAC2015
- Place of Presentation
  Egret Himeji (Hyogo, Himeji)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CAGリピートRNAを標的としたナフチリジン-アザキノロン誘導体の機能評価2015
- Author(s)
  阪田彬裕, 村田亜沙子, 李金星, 松本咲, Li-ping BAI, 堂野主税, 小比賀聡, 中谷和彦
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ(京都府・京都市)
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and properties of functional trinucleotide repeat-binding molecules to induce chemical transformation of trinucleotide repeats2015
- Author(s)
  Takeshi Yamada, Kazuhiko Nakatani, Akiko Michikawa
- Organizer
  Pacifichem2015
- Place of Presentation
  Hawaii(USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Electrical Detection of Polymerase Chain Reaction Using Graphene Field-Effect Transistors2015
- Author(s)
  M. Okano, V. Rajiv, S. Norhayati, T. Ono, F. Takei, Y. Kanai, Y. Ohno, K. Maehashi, K. Inoue, K. Nakatani and K. Matsumoto
- Organizer
  28th International Microprocesses and Nanotechnology Conference
- Place of Presentation
  Toyama
- Year and Date
  2015-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24310165
[Presentation] CAGリピートDNAおよびRNAとナフチリジンーアザキノロン誘導体とのSPRによる結合評価2015
- Author(s)
  阪田彬裕、李金星、Hanping He、Li-ping Bai、村田亜沙子、堂野主税、小比賀聡、中谷和彦
- Organizer
  GE Life Sciences Day 2015
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Design and evaluation of the specific ligand for CTG repeat sequence2015
- Author(s)
  Jun MATSUMOTO, Jinxing Li, Kazuhiko Nakatani
- Organizer
  Pacifichem2015
- Place of Presentation
  Hawaii (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of -1 Ribosomal Frameshifting by Synthetic2015
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Asian 3 Roundtable on Nucleic Acids Suwon, Korea
- Place of Presentation
  Suwon(Korea)
- Year and Date
  2015-09-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of the turn-on type of PCR using hairpin probe with Cytosine-bulge binding fluorescent molecule2015
- Author(s)
  Fumie Takei, Kazuhiko Nakatani
- Organizer
  ISNAC2015
- Place of Presentation
  Himeji
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24310165
[Presentation] Modulation of RNA function by Small Ligands2015
- Author(s)
  Kazuhiko Nakatani
- Organizer
  MetaRNA
- Place of Presentation
  Bordeaux(France)
- Year and Date
  2015-10-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small molecules targeting RNA secondary structures, regulation of -1 ribosomal frame shifting2015
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Seminar at Institute of Molecular Biology and Biotechnology Adam Mickiewicz University, Poznan
- Place of Presentation
  Poznan(Poland)
- Year and Date
  2015-09-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] リピート結合分子をプローブとしたトリヌクレオチドリピート病の化学生物学研究2015
- Author(s)
  Kazuhiko Nakatani
- Organizer
  第38回分子生物学会年会第88回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県・神戸市)
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 小分子によるmiR-29a成熟過程の阻害2014
- Author(s)
  小田部尭広、村田亜沙子、武井史恵、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会　第９回年会
- Place of Presentation
  大阪
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-PROJECT-24310165
[Presentation] Regulation of DNA/RNA structure and function by small molecules2014
- Author(s)
  中谷　和彦
- Organizer
  JSPS UK-Japan Meeting: From Duplexes to Quadruplexes –Understanding DNA Structure and Function
- Place of Presentation
  University of Reading, Reading, England
- Year and Date
  2014-07-03
- Data Source
  KAKENHI-PROJECT-25620134
[Presentation] 核酸に結合する低分子を創る・使う2014
- Author(s)
  中谷和彦
- Organizer
  14-1バイオ・高分子研究会
- Place of Presentation
  長崎
- Year and Date
  2014-09-26
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Toward new FET devices detecting DNA2014
- Author(s)
  Rajiv Kumar Verma, Akiko Michikawa, Norhayati Binti Sabani, Fumie Takei, and Kazuhiko Nakatani
- Organizer
  3rd imec Handai International Symposium
- Place of Presentation
  大阪
- Year and Date
  2014-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24310165
[Presentation] Regulation of RNA Secondary Structure and Function2014
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Imaging and Sensing Biomolecular Function and Assembly
- Place of Presentation
  University of Bordeaux
- Year and Date
  2014-03-14
- Invited
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] 核酸に結合する低分子を創る・使う2014
- Author(s)
  中谷和彦
- Organizer
  2014日本化学会東北支部青森地区講演会
- Place of Presentation
  弘前大学
- Year and Date
  2014-10-03
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Novel PCR Monitoring System Using Hairpin Primer Having Cytosine-Bulge and Covalent Binding Fluorescence Molecule2014
- Author(s)
  Fumie Takei, Xi Chen, Gaigai Yu, Chikara Dohno and Kazuhiko Nakatani
- Organizer
  XXI IRT
- Place of Presentation
  POLAND
- Year and Date
  2014-08-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24310165
[Presentation] Regulation of DNA/RNA structure and function by small molecules2014
- Author(s)
  Kazuhiko Nakatani
- Organizer
  JSPS UK-Japan Meeting : From Duplexes to Quadruplexes-Understanding DNA Structure and Function
- Place of Presentation
  University of Reading
- Year and Date
  2014-07-03
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 小分子による RNA の二次構造制御による機能調節2014
- Author(s)
  中谷　和彦
- Organizer
  第２６回万有札幌シンポジウム
- Place of Presentation
  北海道大学、札幌
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-25620134
[Presentation] Toward new FET devices detecting DNA2014
- Author(s)
  Rajiv Kumar Verma, Akiko Michikawa, Norhayati Binti Sabani, Fumie Takei, and Kazuhiko Nakatani
- Organizer
  3rd imec Handai International Symposium
- Place of Presentation
  グランフロント大阪
- Year and Date
  2014-12-12
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Toward new FET devices detecting DNA2014
- Author(s)
  Rajiv Kumar Verma, Akiko Michikawa, Norhayati Binti Sabani, Fumie Takei, and Kazuhiko Nakatani
- Organizer
  3rd imec Handai International Symposium
- Place of Presentation
  グランフロント大阪
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-14F04039
[Presentation] 小分子によるRNAの二次構造制御による機能調節2014
- Author(s)
  中谷和彦
- Organizer
  第26回万有札幌シンポジウム
- Place of Presentation
  北海道大学
- Year and Date
  2014-07-05
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] New PCR Monitoring System Using DNA Primer Having Cytosine-Bulge and Covalent Binding Fluorescence Molecule2014
- Author(s)
  Fumie Takei, Gaigai Yu, Xi Chen, Chikara Dohno, Nakatani Kazuhiko
- Organizer
  The 17th SANKEN international Symposium 2013/ The 11th SANKEN Nanotechnology Symposium
- Place of Presentation
  大阪大学
- Data Source
  KAKENHI-PROJECT-24310165
[Presentation] Small Organic Molecules regulating RNA Structure and Function2013
- Author(s)
  K. Nakatani
- Organizer
  International Symposium on Challenges in Chemical Biology (ISCCB2013)
- Place of Presentation
  カルカッタ
- Invited
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] ヘアピンプライマーPCR 法を使ったウイルス検出法の開発2013
- Author(s)
  武井史恵、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会　第８回年会
- Place of Presentation
  東京医科歯科大学
- Data Source
  KAKENHI-PROJECT-24310165
[Presentation] HIV-1 mRNAの部分構造RREと低分子の相互作用解析2013
- Author(s)
  津田哲哉・福澄岳雄・中谷和彦
- Organizer
  日本ケミカルバイオロジー学会　第８回年会
- Place of Presentation
  東京医科歯科大学
- Data Source
  KAKENHI-PROJECT-25620134
[Presentation] Synthesis and Application of New Modified DNA Having Cytosine-bulge Binding Fluorescence Molecule2013
- Author(s)
  Fumie Takei, Gaigai Yu, Xi Chen, Chikara Dohno, Nakatani Kazuhiko
- Organizer
  Technologies for Medical Diagonosis and Therapy (G3 Meeting)
- Place of Presentation
  Taiwan
- Data Source
  KAKENHI-PROJECT-24310165
[Presentation] ヘアピンプライマーPCR 法を使ったウイルス検出法の開発2013
- Author(s)
  武井　史恵、中谷　和彦
- Organizer
  第８回ケミカルバイオロジー学会
- Place of Presentation
  東京医科歯科大学
- Data Source
  KAKENHI-PROJECT-24310165
[Presentation] Small Organic Molecules regulating RNA Structure and Function2013
- Author(s)
  K. Nakatani
- Organizer
  International Symposium on Challenges in Chemical Biology (ISCCB2013)
- Place of Presentation
  Indian Institute of Chemical Biology, Kolkata, India
- Year and Date
  2013-01-29
- Data Source
  KAKENHI-PROJECT-24655154
[Presentation] Small Organic Molecules Regulating RNA Structure and Function2013
- Author(s)
  中谷和彦
- Organizer
  15th RNA meeting
- Place of Presentation
  松山　ひめぎんホール
- Invited
- Data Source
  KAKENHI-PROJECT-25620134
[Presentation] Small Organic Molecules regulating RNA Structure and Function2013
- Author(s)
  K. Nakatani
- Organizer
  International Symposium on Challenges in Chemical Biology (ISCCB2013)
- Place of Presentation
  Kolkata, India
- Invited
- Data Source
  KAKENHI-PROJECT-24655154
[Presentation] Design and synthesis of RNA binding ligand for regulating gene expression2012
- Author(s)
  Chikara Dohno, Izumi Kohyama, Kazuhiko Nakatani
- Organizer
  243rd American Chemical Society National Meeting
- Place of Presentation
  San Diego (USA)
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] Synthesis and evaluation of novel naphthyridine derivatives for binding to RNA bulge structure2012
- Author(s)
  T. Otabe, G. Yu, F. Takei, K. Nakatani
- Organizer
  ISNAC2012
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Synthesis of Small Molecule Library for pre-miRNA Secondary Structures2012
- Author(s)
  T. Fukuzumi, A. Murata, Y. Harada, K. Nakatani
- Organizer
  IKCOC-12
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Coumarin derivatives as an indicator for interactions between RNA and small molecules2012
- Author(s)
  T. Tsuda, T. Fukuzumi, K. Nakatani
- Organizer
  The 7th Asia and Oceania Conference on Photochemistry 2012
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Small Organic Molecules Regulating RNA Structure and Function2012
- Author(s)
  K. Nakatani
- Organizer
  The First International Symposium on Biofunctional Chemistry (ISBC2012)
- Place of Presentation
  大岡山、東京工業大学
- Invited
- Data Source
  KAKENHI-PROJECT-24655154
[Presentation] Synthesis and evaluation of hydrophobic G-quadruplex2012
- Author(s)
  T. Shibata, S. Makishi, C. Dohno, K. Nakatani
- Organizer
  ISNAC2012
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Small Organic Molecules Regulating RNA Structure and Function2012
- Author(s)
  K. Nakatani
- Organizer
  The First International Symposium on Biofunctional Chemistry (ISBC2012)
- Place of Presentation
  東京工業大学大岡山
- Year and Date
  2012-11-29
- Data Source
  KAKENHI-PROJECT-24655154
[Presentation] High-throughput Screening of Chemical Libraries for the Discovery of RNA-binding Compounds, RNA 20122012
- Author(s)
  村田亜沙子、福澄岳雄、原田恭枝、梅本詩織、中谷和彦
- Organizer
  the 17th Annual Meeting of the RNA Society
- Place of Presentation
  ミシガン州立大学, Ann Arbor
- Year and Date
  2012-05-29
- Data Source
  KAKENHI-PROJECT-24655154
[Presentation] High allelic discrimination in typing of single nucleotide polymorphisms using allele-specific hairpin primer PCR2012
- Author(s)
  F. Takei, G. Yu, C. Dohno, K. Nakatani
- Organizer
  ISNAC2012
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Synthesis and application of a new modified DNA having cytosine-bulge binding fluorescent molecule2012
- Author(s)
  G. Yu, F. Takei, T. Shibata, C. Dohno, K. Nakatani
- Organizer
  ISNAC2012
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Formation of Ligand-Assisted Complex of Two RNA Hairpin Loops2012
- Author(s)
  K. Nakatani
- Organizer
  The 7th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-7)
- Place of Presentation
  シンガポール
- Invited
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Small Organic Molecules Regulating RNA Structure and Function2012
- Author(s)
  K. Nakatani
- Organizer
  The First International Symposium on Biofunctional Chemistry (ISBC2012)
- Place of Presentation
  東京工業大学
- Invited
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Translation regulation of gene expression by small molecule-induced pseudoknot formation2012
- Author(s)
  S. Matsumoto, C. Hong, A. Murata, K. Nakatani
- Organizer
  ISNAC2012
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Synthesis of Small Molecule Library for pre-miRNA Secondary Structures2012
- Author(s)
  T. Fukuzumi, A. Murata, Y. Harada, K. Nakatani
- Organizer
  RNA 2012, the 17th Annual Meeting of the RNA Society
- Place of Presentation
  ミシガン大学 USA
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Synthesis of Small Molecule Library for pre-miRNA Secondary Structures, RNA 20122012
- Author(s)
  福澄岳雄、村田亜沙子、原田恭枝、中谷和彦
- Organizer
  the 17th Annual Meeting of the RNA Society
- Place of Presentation
  ミシガン州立大学, Ann Arbor
- Year and Date
  2012-05-29
- Data Source
  KAKENHI-PROJECT-24655154
[Presentation] DNA・RNA に結合する小分子現状と課題2011
- Author(s)
  中谷和彦
- Organizer
  第13回生命化学研究会「分子で拓く生命化学」
- Place of Presentation
  仙台(招待講演)
- Year and Date
  2011-01-08
- Data Source
  KAKENHI-PROJECT-18105006
[Presentation] A Light-Driven, Light-switching DNA Device2010
- Author(s)
  中谷和彦
- Organizer
  DNA Photonics Symposium at the PacifiChem2010
- Place of Presentation
  Honolulu, USA(招待講演)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-18105006
[Presentation] ヘアピンタグを持つプライマー使った一塩基多型の蛍光検出2010
- Author(s)
  武井史恵・松永静香・前田あゆみ・萩原正規・中谷和彦
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学 (大阪)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20611010
[Presentation] Application for the fluorescent detection of single nucleotide difference using cytosine bulge hairpin primers and competitor primers2010
- Author(s)
  Fumie Takei, Masaki Hagihara, Kazuhiko Nakatani
- Organizer
  PACIFICHEM 2010
- Place of Presentation
  ハワイコンベンションセンター(米国)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-20611010
[Presentation] Small molecules binding to the hairpin secondary structure of trinucleotide repeat sequences, Nucleic Acid Based2010
- Author(s)
  中谷和彦
- Organizer
  Therapeutics Symposium at the PacifiChem2010
- Place of Presentation
  Honolulu, USA(招待講演)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-18105006
[Presentation] Small molecules binding to the hairpin secondary structure of trinucleotide repeat sequences2010
- Author(s)
  Kazuhiko Nakatani
- Organizer
  Nucleic Acid Based Therapeutics Pacifichem, Honolulu
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-18105006
[Presentation] RNA四重鎖構造を介した遺伝子発現制御2010
- Author(s)
  萩原正規、中谷和彦
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学大阪
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-18105006
[Presentation] ヘアピンプライマーを用いた革新的一塩基多型の蛍光検出法2010
- Author(s)
  武井史恵、萩原正規、中谷和彦
- Organizer
  日本ケミカルバイオロジー研究会第5回年会
- Place of Presentation
  慶応義塾大学(横浜市)
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-20611010
[Presentation] DNA-Labeling by Secondary Structure Inducible Ligand Fluorescence2009
- Author(s)
  Fumie Takei, Masako Igarashi, Masaki Hagihara, Yoshimi Oka, Yoshihiro Soya, Kazuhiko Nakatani
- Organizer
  IKCOC-11
- Place of Presentation
  リーガロイヤルホテル (京都)
- Data Source
  KAKENHI-PROJECT-20611010
[Presentation] mRNAの非翻訳領域に存在する四重鎖構造2009
- Author(s)
  萩原正規、中谷和彦
- Organizer
  日本ケミカルバイオロジー研究会第4回年会
- Place of Presentation
  神戸市産業振興センター
- Year and Date
  2009-05-19
- Data Source
  KAKENHI-PROJECT-18105006
[Presentation] ヘアピンプライマーPCR法による迅速遺伝子診断2009
- Author(s)
  武井史恵, 中谷和彦
- Organizer
  Crest 第5回公開シンポジウム
- Place of Presentation
  みらいCANホール (東京都)
- Year and Date
  2009-08-03
- Data Source
  KAKENHI-PROJECT-20611010
[Presentation] 新規5-メチルシトシンシークエンシング2009
- Author(s)
  岡芳美, 武井史恵, 中谷和彦
- Organizer
  Crest 第5回公開シンポジウム
- Place of Presentation
  みらいCANホール (東京都)
- Year and Date
  2009-08-03
- Data Source
  KAKENHI-PROJECT-20611010
[Presentation] シトシンバルジ-ヘアピンプライマーを使った一塩基多型の蛍光検出2008
- Author(s)
  武井史恵、萩原正規、中谷和彦、曽家義博
- Organizer
  日本化学会第88春季年会
- Place of Presentation
  東京
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Presentation] THE FLUORESCENT DETECTION OF SINGLE NUCLEOTIDE DIFFERENCEUSING CYTOSINE BULGE HAIRPIN PRIMERS2008
- Author(s)
  Fumie Takei, Masaki Hagihara, Yoshimi Oka, Kazuhiko Nakatani
- Organizer
  XXII IUPAC SYMPOSIUM ON PHOTOCHEMISTRY2008
- Place of Presentation
  SWEDEN, GOTHENBURG
- Data Source
  KAKENHI-PROJECT-20611010
[Presentation] Controlling Hybridization by Molecular Glue for DNA2008
- Author(s)
  中谷和彦
- Organizer
  17^<th> International Conference on Organic Synthesis
- Place of Presentation
  Dejon, Korea
- Data Source
  KAKENHI-PROJECT-18105006
[Presentation] シトシンハルジーヘアピンプライマーを使った革新的遺伝子変異の蛍光検出2008
- Author(s)
  武井史恵, 岡芳美, 萩原正規, 曽家義博, 中谷和彦
- Organizer
  日本ケミカルバイオロジー研究会第3回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20611010
[Presentation] The reaction of cytosine with bisulfite by base flipping from the duplex2008
- Author(s)
  Yoshimi Oka, Tao Peng, Fumie Takei, Kazuhiko Nakatani
- Organizer
  Joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids (IRTXVIII)
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20611010
[Presentation] Application for the Fluorescent Detection of Single Nucleotide Difference using Cytosine Bulge Hairpin Primers2007
- Author(s)
  F., Takei, M., Hagihara, Y., Oka, K., Nakatani
- Organizer
  5th 21 COE international Symposium
- Place of Presentation
  Awaji
- Year and Date
  2007-12-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Presentation] Application for the Fluorescent Detection of Single Nucleotide Difference using Cytosine Bulge Hairpin Primers2007
- Author(s)
  F. Takei, M. Hagihara, Y. Oka, K. Nakatani
- Organizer
  第五回 21世紀COEプログラム国際シンポジウム「新産業創造指向インターナノサイエンス」
- Place of Presentation
  淡路島
- Year and Date
  2007-12-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Presentation] ヘアピン構造を持つプライマーを使った遺伝子一塩基多型の蛍光検出2007
- Author(s)
  武井史恵・萩原正規・張錦華・中谷和彦
- Organizer
  日本化学会第87春季年会
- Place of Presentation
  吹田市
- Year and Date
  2007-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Presentation] Application for The Fluorescent Detection of Single Nucleotide Difference Using Hairpin-primer2007
- Author(s)
  F., Takei, M., Hagihara, J., Zhang, K., Nakatani
- Organizer
  The Chemical society of Japan 87th Spring
- Place of Presentation
  Meeting, Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Presentation] Fluorescent Determination of SNPs using N, N'-bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine2007
- Author(s)
  F., Takei, M., Hagihara, J., Zhang, K., Nakatani
- Organizer
  17th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids(IRTXVII), 3rd Spring
- Place of Presentation
  Switzerland
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Presentation] Application for the fluorescent detection of single nucleotide difference using cytosine bulge hairpin primers2007
- Author(s)
  F., Takei, M., Hagihara, Y., Soya, K., Nakatani
- Organizer
  The Chemical society of Japan 87 th Spring Meeting
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Presentation] Fluorescent Determination of SNPs using N, N'-bis(3-aminopropyl)-2,7-diamino-1, 8-naphthyridine2006
- Author(s)
  F. Takei, M. Hagihara, J. Zhang and K. Nakatani
- Organizer
  17th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids(IRTXVII)
- Place of Presentation
  Switzerland
- Year and Date
  2006-09-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18550071
[Presentation] Investigations of bis-fluorophore conjugates for the binding to cytosine bulge DNA
- Author(s)
  VERMA, Rajiv Kumar; NAKATANI, Kazuhiko
- Organizer
  日本化学会第９５春季年会
- Place of Presentation
  日本大学、千葉
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-14F04039
[Presentation] Targeting secondary structures of pre-miRNA by small molecules : Development of potential inhibitors of pre-miRNA processing
- Author(s)
  Asako Murata, Ayako Sugai, Takeo Fukuzumi, Shiori Umemoto, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos, Davos, Switzerland
- Year and Date
  2013-06-11 – 2013-06-16
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] 8位アリール置換型アデニン誘導体の合成とpre-miR-29aに対する結合評価
- Author(s)
  相川春夫、福澄岳雄、原田恭枝、須貝亜矢子、村田亜沙子、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  大阪大学会館
- Year and Date
  2014-06-11 – 2014-06-13
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 小分子とトリヌクレオチドリピートDNAおよびRNAとのSPRによる結合評価
- Author(s)
  阪田彬裕, 李金星, 何漢平, 小比賀聡, 村田亜沙子, 中谷和彦
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-25 – 2015-03-28
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of Novel PCR Primers for Facile Gene Detection
- Author(s)
  中谷和彦
- Organizer
  A3RONA 2014 China
- Place of Presentation
  Xiamen University, China
- Year and Date
  2014-10-17 – 2014-10-19
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small Organic Molecules Regulating RNA Structure and Function "
- Author(s)
  Kazuhiko Nakatani
- Organizer
  The 1st Osaka University - EPFL International Symposium
- Place of Presentation
  銀杏会館、大阪大学
- Year and Date
  2013-12-02 – 2013-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] HIV-1 mRNAの部分構造RREと低分子の相互作用解析
- Author(s)
  津田哲哉・福澄岳雄・中谷和彦
- Organizer
  日本ケミカルバイオロジー学会　第８回年会
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2013-06-19 – 2013-06-21
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] 小分子で誘起されたRNAシュードノット構造によるフレームシフト機構の制御
- Author(s)
  松本咲、洪昌峰、村田亜沙子、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会　第８回年会
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2013-06-19 – 2013-06-21
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Synthesis and design of RNA binding molecules in enthalpy-driven manner
- Author(s)
  Nozomi Natsuhara, Yue Di, Tetsuya Tsuda, Sanjukta Mukherjee, Kazuhiko Nakatani
- Organizer
  RNA 2014 The 19th Annual Meeting of the RNA Society
- Place of Presentation
  Centre des Congrès de Québec, Québec, Canada
- Year and Date
  2014-06-03 – 2014-06-08
- Data Source
  KAKENHI-PROJECT-25620134
[Presentation] CTGリピート選択的小分子リガンドの探索
- Author(s)
  松本惇・李金星・中谷和彦
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学
- Year and Date
  2015-03-26 – 2015-03-29
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Translational regulation by ligand-inducible formation of RNA pseudoknot
- Author(s)
  Saki Matsumoto, Changfeng Hong, Asako Murata, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos, Davos, Switzerland
- Year and Date
  2013-06-11 – 2013-06-16
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Small Organic Molecules Regulating RNA Structure and Function
- Author(s)
  Kazuhiko Nakatani
- Organizer
  15th RNA meeting in Matsuyama
- Place of Presentation
  松山
- Year and Date
  2013-07-24 – 2013-07-26
- Invited
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Targeting CUG trinucleotide repeats with synthetic ligands
- Author(s)
  Jinxing Li, Jun Matsumoto, Kazuhiko Nakatani
- Organizer
  ISNAC2014
- Place of Presentation
  北九州国際会議場
- Year and Date
  2014-11-05 – 2014-11-07
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Coumarin fluorochrome binds to Rev responsible element RNA with extremely large absorption shift
- Author(s)
  Tetsuya Tsuda, Takeo Fukuzumi, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos, Davos, Switzerland
- Year and Date
  2013-06-11 – 2013-06-16
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Small Molecule Interaction to RNA
- Author(s)
  K. Nakatani
- Organizer
  A3RONA 2012 KOREA
- Place of Presentation
  POSTEC, KOREA
- Invited
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Design and synthesis of novel small-molecule ligand for targeting CUG trinucleotide repeat
- Author(s)
  LI, Jinxing; MATSUMOTO, Jun; NAKATANI, Kazuhiko
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学
- Year and Date
  2015-03-26 – 2015-03-29
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of amphiphilic DNA for building of 2D nanostructure at hydrophobic-hydrophilic interface
- Author(s)
  S. Makishi, T. Shibata, C. Dohno, K. Nakatani
- Organizer
  The 5th edition of the Young Scientist Symposium by the European Institute of Chemistry and Biology (IECB)
- Place of Presentation
  ボルドー大学、フランス
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Toward Regulation of RNA Structure and Function by Small Molecules
- Author(s)
  Kazuhiko Nakatani
- Organizer
  A3RONA 2013 Kobe
- Place of Presentation
  ポートピアホテル、神戸
- Year and Date
  2013-08-30 – 2013-09-01
- Invited
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Synthesis and design of RNA binding molecules in enthalpy-driven manner
- Author(s)
  Nozomi Natsuhara, Yue Di, Tetsuya Tsuda, Sanjukta Mukherjee, Kazuhiko Nakatani
- Organizer
  RNA 2014 The 19th Annual Meeting of the RNA Society
- Place of Presentation
  Quebec, Canada
- Year and Date
  2014-06-03 – 2014-06-08
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 小分子によるリボソームフレームシフトの制御
- Author(s)
  松本咲、村田亜沙子、洪昌峰、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  大阪大学会館
- Year and Date
  2014-06-11 – 2014-06-13
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] ミスマッチ結合分子固定化Au-SiO2表面の作成と結合評価
- Author(s)
  道川　滉子・VERMA　Rajiv Kumar・中谷　和彦
- Organizer
  日本化学会第９５春季年会
- Place of Presentation
  日本大学、千葉
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-14F04039
[Presentation] Suppression of miR-29a maturation by ligand binding
- Author(s)
  OTABE, Takahiro; MURATA, Asako; TAKEI, Fumie; NAKATANI, Kazuhiko
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos, Davos, Switzerland
- Year and Date
  2013-06-11 – 2013-06-16
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Facile Detection of PCR Progress by Hairpin Primer PCR
- Author(s)
  中谷和彦
- Organizer
  東北大学電気通信研究所ー阪大産研　交流会
- Place of Presentation
  蔵王、山形
- Year and Date
  2013-07-31 – 2013-08-02
- Invited
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] ヘアピンプライマーPCR 法を使ったウイルス検出法の開発
- Author(s)
  武井史恵、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会　第８回年会
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2013-06-19 – 2013-06-21
- Data Source
  KAKENHI-PROJECT-23241073

1. TAKEI Fumie (30252711)

# of Collaborated Projects: 10 results

# of Collaborated Products: 67 results
2. ZHOU Daーyang (00324848)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. HAGIHARA Masaki (40403000)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
4. DOHNO Chikara (60420395)

# of Collaborated Projects: 4 results

# of Collaborated Products: 74 results
5. SAITO Isao (20026082)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. MURATA Asako (50557121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 54 results
7. FUKUZUMI Takeo (00592768)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
8. AIKAWA Haruo (70547322)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
9. Nakamori Masayuki (60630233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
10. 柴田知範 (80711960)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
11. 山田剛史 (80633263)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
12. VERMA RAJIV

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
13. SUGIYAMA Hiroshi (50183843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 藤塚守 (40282040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 真嶋哲朗 (00165698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 新井達郎 (50151139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAKAHASHI Masanori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAGAI Takeharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. AOKI Toshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 浜田道昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 山口兆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 二宮賢介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 工位武治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 佐藤和信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKATANI Kazuhiko 中谷 和彦

Research Projects

Research Products

Co-Researchers

Elucidation of the binding pathway of mismatch-binding molecules to abnormally elongated repeat sequences and their shortening-inducing effectsPrincipal Investigator

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Challenge in computational science toward the identification of the reaction pathway for the formation of nucleic acids-small molecule complexesPrincipal Investigator

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Creation of repeat binding molecules that specifically modify repeat sequences chemicallyPrincipal Investigator

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Development of novel microRNA detection system

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Chemical Biology Studies on Trinucleotide Repeat Disease using Repeat-Binding MoleculesPrincipal Investigator

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ナノポアシーケンサーにおける一塩基分解能を達成する塩基読み取り分子に関する研究Principal Investigator

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Determination of molecular mechanism of loop-specific structural change and inhibitory effect for Dicer mediated reactionPrincipal Investigator

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Regulation of secondary structure by RNA loop-loop interaction inducedsmall molecular bindingPrincipal Investigator

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Novel high-sensitivity detection method of virus using a hairpin primer PCR

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Synthesis of 8-substituted purine chemical library and riboswitch-reengineeringPrincipal Investigator

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Photoresponsive RNA-binding ligands for regulation of RNA functions

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Application for the fluorescent detection of single nucleotide difference using cytosine bulge hairpin primers

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Functional Control by Modulating the Nucleic Acid Structure Based on Mismatch Base Pair StabilizationPrincipal Investigator

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NAKATANI Kazuhiko 中谷和彦