KAWAKAMI Toru 川上徹

Researcher Number	70273711
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2020: 大阪大学, 蛋白質研究所, 准教授 2012 – 2017: 大阪大学, たんぱく質研究所, 准教授 2014: 大阪大学, 蛋白質研究所, 准教授 2007 – 2011: Osaka University, 蛋白質研究所, 准教授 2004 – 2006: 大阪大学, 蛋白質研究所, 助教授 … More 2003: 大阪大学, たんぱく質研究所, 助教授 2000 – 2002: Institute for Protein Research, Instructor, たんぱく質研究所, 助手 2001: 大阪大学, 蛋白質研究所, 助手 1998 – 1999: 大阪大学, 蛋白質研究所, 助手 Less
Review Section/Research Field	Principal Investigator Chemistry related to living body / Basic Section 37010:Bio-related chemistry / Bio-related chemistry / Bioorganic chemistry Except Principal Investigator Genome biology / Bioorganic chemistry / Chemical pharmacy / Structural biochemistry / Physical pharmacy / Living organism molecular science / Biological Sciences / Cell biology
Keywords	Principal Investigator ペプチドチオエステル / ケミカルライゲーション / ペプチド合成 / DNAメチル化 / ユビキチン / 翻訳後修飾 / ヒストン / 生体分子 / ライゲーション / ペプチド … More / 蛋白質 / ジケトピペラジン / N-Sアシル基転位反応 / 膜蛋白質 / ヌクレオソーム / チイラン / イソペプチド / ペプチドライゲーション / 部位特異的修飾 / チオエステル / 受容体 / タンパク質 / N-Sアシル基転移反応 / 有機化学 / 合成化学 / 蛋白質合成 / CPEライゲーション / ペプチドエステル / N-Sアシル転移 / 光反応 / ライゲーション補助基 / 拡張型ペプチドライゲーション / プペプチドチオエステル / ペプチド結合形成 / 安定同位体標識 / Max蛋白質 / リン酸化ペプチド … More Except Principal Investigator 化学合成 / native chemical ligation / GPCR / ライブラリー / ヒストン / 選択的縮合法 / ペプチドチオエステル / 補助基 / ライゲーション法 / 膜蛋白質 / 有機化学 / ヒストン修飾 / 化学修飾 / ユビキチン化 / 修飾ヒストン / auxiliary / thioester method / coupling conditions / chemical synthesis / peptide thioester / nociceptin receptor / Argタグ / 7回膜貫通型受容体 / チオスルホネート基 / チオエステル法 / 縮合条件 / ノシセプチン受容体 / library / Solid phase synthesis / HTLV-1 / Transition state mimetic / Protease / Enzyme inhibitor / Asvmmetirc aldol reaction / コンビナトリアル合成 / 固相合成 / ヒト白血病ウイルス / 基質遷移状態 / プロテアーゼ / 酵素阻害剤 / 不斉アルドール反応 / phage library / interferon γ / synthetic peptide / antagonist / interleukin-18 / 膜貫通ドメイン / 抗体 / 合成ペプチド / IL-18受容体 / IL-18 / インターフェロン18(IL-18) / IL-18区分ペプチド / インターフェロンγ産生 / ファージライブラリー / アンタゴニスト / インターロイキン18(IL-18) / ABCトランスポーター / 重金属結合タンパク質 / 安定化人工脂質 / 高密度リポタンパク質 / 膜タンパク質 / 再構成 / ペプチド / アポA-I / 脂質膜ディスク / HDL / ライゲ-ション法 / ヒストンH3 / メチル化リシン / 遺伝子発現 / 翻訳後修飾 / メチル化 / Argタグ補助基 / 4回膜貫通型受容体 / 光反応性補助基 / Fmoc法 / v-ATPase / EGF 受容体 / 電位依存性プロトンチャネル / EGF受容体 / 膜近傍部位 / 合成法 / 溶解性 / オキザロイル基 / 選択的化学修飾反応 / 末端アミノ基 / グリオキシロイル基 / 過ヨウ素酸ナトリウム / メチル化DNA結合ドメイン / N-末端特異的標識 Less

Synthesis of modified histones and its use for preparation of asymmetric nucleosomesPrincipal Investigator
- Principal Investigator
  
  Kawakami Toru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Osaka University
Synthesis of histone protein for the post-translationally modified protein libraryPrincipal Investigator
- Principal Investigator
  
  Kawakami Toru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka University
Development of methods for preparing histones with various modifications
- Principal Investigator
  
  Suetake Isao
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Genome biology
- Research Institution
  Koshien University
  Osaka University
Development of HDL-like lipid membrane discs for reconstitution of membrane proteins
- Principal Investigator
  
  SAITO Hiroyuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Development of a method for protein labeling by the use of intramolecular thioester-forming unitPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Toru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
Development of a new method for peptide ligation based on the N-S acyl shift reactionPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Toru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
Development of a synthetic method of modified histone aiming at elucidation of the molecular mechanism of the gene expression regulation
- Principal Investigator
  
  AIMOTO Saburo
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University
新規ペプチドライゲーション法の開発とそれを用いる膜蛋白質合成Principal Investigator
- Principal Investigator
  
  川上徹
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
Development of a method for membrane protein synthesis based on ligation chemistry
- Principal Investigator
  
  AIMOTO Saburo
- Project Period (FY)
  2003 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
膜貫通型蛋白質の合成を目的とする新規なペプチドライゲーション法の開発Principal Investigator
- Principal Investigator
  
  川上徹
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
Development of a method for chemical synthesis of G-protein coupled receptor
- Principal Investigator
  
  AIMOTO Saburo
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Osaka University
蛋白質のN-末端特異的蛍光標識法の開発と生細胞内メチル化DNAの直接検出法の開発
- Principal Investigator
  
  AIMOTO Saburo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
Combinatorial Synthesis of Transition State Mimetic Inhibitor Using Asymmetric Aldol, Reaction
- Principal Investigator
  
  AKAJI Kenichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Osaka University
発現蛋白質を合成ブロックとして用いる高純度長鎖ペプチド合成法の開発Principal Investigator
- Principal Investigator
  
  川上徹
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Osaka University
Suppression of the inflammatory cytokine IL-18 activity by controlling the receptor function
- Principal Investigator
  
  AIMOTO Saburo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University

[Book] 最新ペプチド合成技術とその創薬研究への応用2012
- Author(s)
  川上徹, 相本三郎
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-21550155
[Book] 最新ペプチド合成技術とその創薬研究への応用(システイン残基におけるS-ペプチド体を利用するペプチドライゲーション法の開発)2012
- Author(s)
  川上徹, 相本三郎
- Total Pages
  7
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Enhanced processivity of Dnmt1 by monoubiquitinated histone H32020
- Author(s)
  Y. Mishima, L. Brueckner, S. Takahashi, T. Kawakami, J. Otani, A. Shinohara, K. Takeshita, R. G. Garvilles, M. Watanabe, N. Sakai, H. Takeshima, C. Nachtegael, A. Nishiyama, M. Nakanishi, K. Arita, K. Nakashima, H. Hojo, I. Suetake
- Journal Title
  
  Genes Cells
  
  Volume: 25 Issue: 1 Pages: 22-32
- DOI
  10.1111/gtc.12732
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05316, KAKENHI-PROJECT-18K06095, KAKENHI-PROJECT-18K14681, KAKENHI-PROJECT-19K17878, KAKENHI-PLANNED-15H05973, KAKENHI-PROJECT-18H02392, KAKENHI-PROJECT-19H04048, KAKENHI-PROJECT-18K15211, KAKENHI-PLANNED-19H05740, KAKENHI-PLANNED-19H05741, KAKENHI-PROJECT-17H01398, KAKENHI-PROJECT-19H00981, KAKENHI-ORGANIZER-19H05739
[Journal Article] Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation2020
- Author(s)
  A. Nishiyama, C. Mulholland, S. Bultmann, S. Kori, A. Endo, Y. Saeki, W. Qin, C. Trummer, Y. Chiba, H. Yokoyama, S. Kumamoto, T. Kawakami, H. Hojo, G. Nagae, H. Aburatani, K. Tanaka, K. Arita, H. Leonhardt, M. Nakanishi
- Journal Title
  
  Nat. Commun.
  
  Volume: 11 Issue: 1 Pages: 1222-1222
- DOI
  10.1038/s41467-020-15006-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05316, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PUBLICLY-19H05285, KAKENHI-PLANNED-19H05744, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-18H02392, KAKENHI-PROJECT-19H03153, KAKENHI-PROJECT-19J22030, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-17H01398, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18K07963, KAKENHI-ORGANIZER-19H05739
[Journal Article] Glycopeptide synthesis based on a TFA-labile protection strategy and one-pot four-segment ligation for the synthesis of O-glycosylated histone H2A2019
- Author(s)
  Y. Asahina, T. Kawakami, H. Hojo
- Journal Title
  
  Eur. J. Org. Chem.
  
  Volume: - Issue: 9 Pages: 1915-1920
- DOI
  10.1002/ejoc.201801885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05316, KAKENHI-PROJECT-18K14336, KAKENHI-PROJECT-16H04180
[Journal Article] Chemical synthesis of the ubiquitinated form of histone H3 and its effect on DNA methyltransferase 12019
- Author(s)
  T. Kawakami, Y. Mishima, M. Takazawa, H. Hojo, I. Suetake
- Journal Title
  
  J. Pept. Sci.
  
  Volume: 25 Issue: 9
- DOI
  10.1002/psc.3200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05316, KAKENHI-PROJECT-18K06095, KAKENHI-PROJECT-19K17878
[Journal Article] One-pot native chemical ligation by combination of two orthogonal thioester precursors2017
- Author(s)
  Y. Asahina, Toru Kawakami and Hironobu Hojo
- Journal Title
  
  Chem. Commun
  
  Volume: 53 Issue: 13 Pages: 2114-2117
- DOI
  10.1039/c6cc10243c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04180, KAKENHI-PROJECT-15K21124, KAKENHI-PROJECT-15K05565
[Journal Article] RFTS-dependent negative regulation of Dnmt1 by nucleosome structure and histone tails.2017
- Author(s)
  Mishima Y, Brueckner L, Takahashi S, Kawakami T, Arita K, Oka S, Otani J, Hojo H, Shirakawa M, Shinohara A, Watanabe M, Suetake I
- Journal Title
  
  FEBS J.
  
  Volume: 284 Issue: 20 Pages: 3455-3469
- DOI
  10.1111/febs.14205
- NAID
  120006537075
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14418, KAKENHI-PLANNED-15H05973, KAKENHI-PROJECT-16H04180, KAKENHI-PROJECT-16H04742, KAKENHI-PROJECT-15K05565, KAKENHI-PROJECT-16K18490
[Journal Article] 1.Synthesis of ubiquitylated histone H3 using a thiirane linker for chemical ligation2017
- Author(s)
  T. Kawakami, Y. Mishima, H. Hojo, I Suetake
- Journal Title
  
  J. Pept. Sci.
  
  Volume: 印刷中 Issue: 7-8 Pages: 532-538
- DOI
  10.1002/psc.2976
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K05565, KAKENHI-PROJECT-15K14418, KAKENHI-PROJECT-16H04180
[Journal Article] Structure of the Dnmt1 reader module complexed with a unique two-mono-ubiquitin mark on histone H3 reveals the basis for DNA methylation maintenance.2017
- Author(s)
  Ishiyama S, Nishiyama A, Saeki Y, Moritsugu K Morimoto D, Yamaguchi L, Arai N, Matsumura R, Kawakami T, Mishima Y, Hojo H, Shimamura S, Ishikawa F, Tajima S, Tanaka K, Ariyoshi M, Shirakawa M, Ikeguchi M, Kidera A, Suetake I, Arita K, Nakanishi M
- Journal Title
  
  Mol Cell
  
  Volume: 68 Issue: 2 Pages: 350-360
- DOI
  10.1016/j.molcel.2017.09.037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14418, KAKENHI-PROJECT-16K14714, KAKENHI-PROJECT-16K18503, KAKENHI-PROJECT-26293018, KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-16H04180, KAKENHI-PROJECT-16H04780, KAKENHI-PROJECT-16H04818, KAKENHI-PROJECT-15K05565, KAKENHI-PROJECT-15K18520, KAKENHI-PROJECT-26000014
[Journal Article] Synthesis of modified histone proteins by CPE ligation using a recombinant peptide2016
- Author(s)
  T. Kawakami, R. Yoshikawa, Y. Fujiyoshi, Y. Mishima, H. Hojo, S. Tajima, I. Suetake
- Journal Title
  
  Peptide Science 2015
  
  Volume: - Pages: 117-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05565
[Journal Article] A thiirane linker for isopeptide mimetics by peptide ligation2016
- Author(s)
  T. Kawakami, Y. Mishima, M. Kinoshita, Y.-H. Lee, I. Suetake
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 57 Issue: 19 Pages: 2112-2115
- DOI
  10.1016/j.tetlet.2016.04.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K05565
[Journal Article] Synthesis of Histone Proteins by CPE Ligation using a Recombinant Peptide as the C-Terminal Building Block2015
- Author(s)
  T. Kawakami, R. Yoshikawa, Y. Fujiyoshi, Y. Mishima, Hi. Hojo, S. Tajima, I. Suetake
- Journal Title
  
  J. Biochem.
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24550187
[Journal Article] Peptide Thioester Formation via an Intramolecular N toS Acyl Shift for Peptide Ligation2015
- Author(s)
  T. Kawakami
- Journal Title
  
  Topics in Current Chemistry
  
  Volume: 362 Pages: 107-136
- DOI
  10.1007/128_2014_575
- ISBN
  9783319191850, 9783319191867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24550187
[Journal Article] Synthesis of Histone Proteins by CPE Ligation using a Recombinant Peptide as the C-Terminal Building Block2015
- Author(s)
  Kawakami T*,Yoshikawa R, Fujiyoshi Y, Mishima Y, Hojo H, Tajima S, Suetake I
- Journal Title
  
  J. Biochem
  
  Volume: 158 Issue: 5 Pages: 403-411
- DOI
  10.1093/jb/mvv056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14418
[Journal Article] Phenacyl Group as a Protecting Group for Thiol in the Use of Recombinant Peptides as Building Blocks for the Peptide Ligation Strategy2015
- Author(s)
  T. Kawakami, H. Hojo
- Journal Title
  
  Peptide Science 2014
  
  Volume: - Pages: 117-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24550187
[Journal Article] Enhancement in the Rate of Conversion of Peptide Cys-Pro esters to Peptide Thioesters by Structural Modification2014
- Author(s)
  T. Kawakami, A. Kamauchi, E. Harada, S. Aimoto
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 55 Issue: 1 Pages: 79-81
- DOI
  10.1016/j.tetlet.2013.10.121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24550187
[Journal Article] Total Chemical Synthesis and Semi-synthesis of Histone H3 and H4 by the Use of Cys-Pro Ester Auto-activating Unit for the Thioester2014
- Author(s)
  T. Kawakami, Y. Akai, R. Yoshikawa, I. Suetake, S. Tajima, S. Aimoto
- Journal Title
  
  Peptide Science 2013
  
  Volume: - Pages: 47-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24550187
[Journal Article] Sequential Peptide Ligation by the Combination of Cys-Pro Ester and Thioester Methods: An Application to a Synthesis of Histone H32013
- Author(s)
  T. Kawakami, Y. Akai, H. Fujimoto, C. Kita, L. Takemura, Y. Aoki, M. Waseda, S. Aimoto
- Journal Title
  
  Peptide Science 2012
  
  Volume: - Pages: 77-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24550187
[Journal Article] Sequential Peptide Ligation by Combining the Cys-Pro Ester (CPE) and Thioester Methods and its Application to the Synthesis of Histone H3 Containing a Trimethyl Lysine Residue2013
- Author(s)
  T. Kawakami, Y. Akai, H. Fujimoto, C. Kita, Y. Aoki, T. Konishi, M. Waseda, L. Takemura, S. Aimoto
- Journal Title
  
  Bull. Chem. Soc. Jpn
  
  Volume: 86 Issue: 6 Pages: 690-697
- DOI
  10.1246/bcsj.20130026
- NAID
  10031176002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24550187
[Journal Article] N-Sアシル基転位反応を用いるペプチドチオエステル合成法の開発2012
- Author(s)
  川上徹, 相本三郎
- Journal Title
  
  有機合成化学協会誌
  
  Volume: 70巻 Pages: 166-176
- NAID
  10030481479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Formation of peptide thioesters by the use of modified Cys-Pro Ester(CPE) autoactivating unit2012
- Author(s)
  A. Kamauchi, E. Harada, S. Aimoto, T. Kawakami
- Journal Title
  
  Peptide Science 2011
  
  Pages: 135-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Formation of peptide thioesters by the use of modified Cys-Pro Ester (CPE) autoactivating unit2012
- Author(s)
  A.Kamauchi, E.Harada, S.Aimoto, T.Kawakami
- Journal Title
  
  Peptide Science 2011
  
  Pages: 135-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Peptide ligation via thioester formation at the cysteine residue2011
- Author(s)
  T.Kawakami, S.Aimoto
- Journal Title
  
  Peptide Science 2010
  
  Pages: 47-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Peptide Ligation via thioester formation at the cysteine residue2011
- Author(s)
  T. Kawakami, S. Aimoto
- Journal Title
  
  Peptide Science 2010, Japanese Peptide Society
  
  Pages: 47-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Peptide Thioester Formation by an N to S Acyl Shift Reaction at the Cysteinyl Prolyl Cysteine Position2010
- Author(s)
  T.Kawakami, S.Shimizu, S., Aimoto
- Journal Title
  
  Bull.Chem.Soc.Jpn
  
  Volume: 83 Pages: 570-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Formation of Peptide Thioesters by an N to S Acyl Shift Reaction at the Cysteinyl Prolyl Cysteine Position2010
- Author(s)
  S.Shimizu, T.Kawakami, S., Aimoto
- Journal Title
  
  Peptide Science 2009
  
  Pages: 153-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Formation of Peptide Thioesters by an N to S Acyl Shift Reaction at the Cysteinyl Prolyl Cysteine Position2010
- Author(s)
  Sakiko Shimizu, Saburo Aimoto, Toru Kawakami
- Journal Title
  
  Peptide Science 2009
  
  Pages: 153-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Peptide Thioester Formation by an N to S Acyl Shift Reaction at the Cysteinyl Prolyl Cysteine Position2010
- Author(s)
  T. Kawakami, S. Shimizu, S. Aimoto
- Journal Title
  
  Bulletin of Chemical Society of Japan
  
  Volume: 83巻 Pages: 570-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Synthesis of Peptide Thioesters Based on an N to S Acyl Shift Reaction2010
- Author(s)
  Toru Kawakami, Sakiko Shimizu, Saburo Aimoto
- Journal Title
  
  Peptide Science 2009
  
  Pages: 79-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Formation of Peptide Thioesters by an N to S Acyl Shift Reaction at the Cysteinyl Prolyl Cysteine Position2010
- Author(s)
  S.Shimizu, T.Kawakami, S., Aimoto
- Journal Title
  
  Peptide Science 2009 (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Peptide Diketopiperazine Thioester Formation at the Cys-Pro-Cys Position2010
- Author(s)
  T. Kawakami, S. Shimizu, S. Aimoto
- Journal Title
  
  Peptides 2010 : Tales of Peptides, European Peptide Society
  
  Pages: 52-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Synthesis of Peptide Thioester Based on N to S Acyl Shift Reaction2010
- Author(s)
  T.Kawakami, S.Shimizu, S., Aimoto
- Journal Title
  
  Peptide Science 2009 (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Synthesis of Peptide Thioester Based on N to S Acyl Shift Reaction2010
- Author(s)
  T.Kawakami, S.Aimoto
- Journal Title
  
  Peptide Science 2009
  
  Pages: 79-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Synthesis of Peptide Thioesters Based on an N to S Acyl Shift Reaction2010
- Author(s)
  T.Kawakami
- Journal Title
  
  Peptide Science 2009 (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Peptide Diketopiperazine Thioester Formation at the Cys-Pro-Cys Position2010
- Author(s)
  T.Kawakami, S.Shimizu, S.Aimoto
- Journal Title
  
  Peptides 2010 : Tales of Peptides
  
  Pages: 52-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Synthesis of peptide thioesters based on an N to S acyl shift reaction2010
- Author(s)
  T. Kawakami, S. Shimizu, S. Aimoto
- Journal Title
  
  Peptide Science 2009, Japanese Peptide Society
  
  Pages: 79-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Peptide Thioester Formation by an N to S Acyl Shift Reaction at the Cysteinyl Prolyl Cysteine Position2010
- Author(s)
  T.Kawakami, S.Shimizu, S., Aimoto
- Journal Title
  
  Bull.Chem.Soc.Jpn 83(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Formation of peptide thioesters by an N to S acyl shift reaction at the cysteinyl prolyl cysteine position2010
- Author(s)
  S. Shimizu, S. Aimoto, T. Kawakami
- Journal Title
  
  Peptide Science 2009, Japanese Peptide Society
  
  Pages: 153-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Methylthio Groups for Thiol Protection that realize the Sequential Ligation by Native Chemical Ligation followed by Thioester method2009
- Author(s)
  Yuichi Akai, Lisa Takemura, Yuko Aoki, Masazumi Waseda, Toru Kawakami, Saburo Aimoto
- Journal Title
  
  Peptide Science 2008
  
  Pages: 201-201
- NAID
  10027166211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Synthesis of Peptide Thioester, by the Cysteinyl Prolyl Ester (CPE) Method2009
- Author(s)
  Toru Kawakami, Saburo Aimoto
- Journal Title
  
  Peptide Science 2008
  
  Pages: 171-172
- NAID
  10027166150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Synthesis of peptide thioesters via an N-S acyl shift reaction under mild acidic conditions using an N-4, 5-dimethoxy-2-mercaptobenzyl auxiliary group2009
- Author(s)
  Ken'ichiro Nakamura, Tomoki Kanao, Tomoya Uesugi, Toshiaki Hara, Takeshi Sato, Toru Kawakami, Saburo Aimoto
- Journal Title
  
  J. Peptide Sci 15
  
  Pages: 731-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] The Use of a Cysteinyl Prolyl Ester (CPE) Autoactivating Unit in Peptide Ligation Reactions2009
- Author(s)
  T. Kawakami
- Journal Title
  
  Tetrahedron (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] The Use of a Cysteinyl Prolyl Ester (CPE) Autoactivating Unit in Peptide Ligation Reactions2009
- Author(s)
  Toru Kawakami, Saburo Aimoto
- Journal Title
  
  Tetrahedron 65
  
  Pages: 3871-3877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] 2-Nitrobenzylcarbamate-type Photocleavable Linker Having Fmoc-aminoalkyloxy Group: Preparation and Application to Peptide Purification2009
- Author(s)
  Toshiaki Hara, Akira Tainosho, Toru Kawakami, Saburo Aimoto
- Journal Title
  
  Peptide Science 2008
  
  Pages: 199-201
- NAID
  10027166207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Peptide purification by affinity chromatography based on a-ketoacyl group chemistry2009
- Author(s)
  Toshiaki Hara, Akira Tainosho, Ken'ichiroh Nakamura, Takeshi Sato, Toru Kawakami, Saburo Aimoto
- Journal Title
  
  J. Peptide Sci 15
  
  Pages: 369-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Peptide Purification Using The Selective Reaction Between Aminooxy Group and Isothiocyanate Group2009
- Author(s)
  Akira Tainosho, Toshiaki Hara, Ken'ichiro Nakamura, Toru Kawakami, Saburo Aimoto
- Journal Title
  
  Peptide Science 2008
  
  Pages: 205-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] The use of a cysteinyl prolyl ester (CPE) autoactivating unit in peptide ligation reactions2009
- Author(s)
  T.Kawakami, S.Aimoto
- Journal Title
  
  Tetrahedron 65
  
  Pages: 3871-3877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Peptide thioester formation and ligation using a cysteinyl prolyl ester(CPE) autoactivating unit, Peptides2009
- Author(s)
  T. Kawakami, S. Aimoto
- Journal Title
  
  American peptide Society
  
  Pages: 29-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Peptide purification by affinity chromatography based on α-ketoacyl group chemistry2009
- Author(s)
  T. Hara, A. Tainosho, K. Nakamura, T. Sato, T. Kawakami, S. Aimoto
- Journal Title
  
  J. Peptide Sci. 15
  
  Pages: 369-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] The Use of a Cysteinyl Prolyl Ester(CPE)Autoactivating Unit in Peptide Ligati on Reactions2009
- Author(s)
  T. Kawakami
- Journal Title
  
  Tetrahedron (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] The use of a cysteinyl prolyl ester(CPE) autoactivating unit in peptide ligation reactions2009
- Author(s)
  T. Kawakami, S. Aimoto
- Journal Title
  
  Tetrahedron
  
  Volume: 65巻 Pages: 3871-3877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] Synthesis of peptide thioesters via an N-S acyl shift reaction under mild acidic conditions on an N-4, 5-dimethoxy-2-mercaptobenzyl auxiliary group2009
- Author(s)
  K. Nakamura, T. Kanao, T. Uesugi, T. Hara, T. Sato, T. Kawakami, S. Aimoto
- Journal Title
  
  Journal of Peptide Science
  
  Volume: 15巻 Pages: 731-737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550155
[Journal Article] The use of a cysteinyl prolyl ester (CPE) autoactivating unit in peptide ligation reactions2009
- Author(s)
  T. Kawakami, S. Aimoto
- Journal Title
  
  Tetrahedron 65
  
  Pages: 3871-3877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Peptide purification by affinity chromatography based on α-ketoacyl group chemistry2009
- Author(s)
  Toshiaki Hara, Akira Tainosho, Ken'ichiroh Nakamura, Takeshi Sato, Toru Kawakami, Saburo Aimoto
- Journal Title
  
  J. Peptide Sci. 15
  
  Pages: 369-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Synthesis of a Partial Sequence of Site-2008
- Author(s)
  Hisao Fujimoto, Chieko Kita, Akira Tainosho, Yuichi Akai, Lisa Takemura, Hitomi Kanda, Toru, Kawakami, Saburo Aimoto
- Journal Title
  
  Specifically Methylated Histone H3 Peptide Science 2007
  
  Pages: 209-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Peptide Ligation Using the Cysteinyl Prolyl Ester (CPE) Activating Unit at the Carboxy Terminus2007
- Author(s)
  T.Kawakami
- Journal Title
  
  Chem. Lett. 36
  
  Pages: 76-77
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Peptide Thioester Synthesis via an Auxiliary-Mediated N-S Acyl Shift Reaction in Solution2007
- Author(s)
  Nakamura, K., Mori, H., Kawakami, T., Hojo, H., Nakahara, Y., Aimoto, S.
- Journal Title
  
  International Journal of Peptide Research and Therapeutics E-pub(印刷中)
- Data Source
  KAKENHI-PROJECT-17750158
[Journal Article] Peptide Ligation Using a Building Block Having a Cysteinyl Prolyl Ester (CPE) Autoactivating Unit at the Carboxy Terminus2007
- Author(s)
  Toru Kawakami, Saburo Aimoto
- Journal Title
  
  Chem. Lett 36
  
  Pages: 76-77
- NAID
  10018663050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Sequential peptide ligation by using a controlled cysteinyl prolyl ester (CPE) autoactivating unit.2007
- Author(s)
  T. Kawakami
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 1903-1905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Peptide Ligation Using a Building Block Having a Cysteinyl Prolyl Ester (CPE) Autoactivating Unit at the Carboxy Terminus2007
- Author(s)
  Kawakami, T., Aimoto, S.
- Journal Title
  
  Chemistry Letters 36(1)
  
  Pages: 76-77
- Data Source
  KAKENHI-PROJECT-17750158
[Journal Article] Peptide Ligation Using the Cysteinyl Prolyl Ester (CPE) Activating Unit at the Carboxy Terminus2007
- Author(s)
  T. Kawakami, S. Aimoto
- Journal Title
  
  Chem. Lett. 36
  
  Pages: 76-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Polypeptide Synthesis via the N-to S-Acyl Shift Reaction2007
- Author(s)
  Toru Kawakami, Ken'ichiro Nakamura, Saburo Aimoto
- Journal Title
  
  Peptides 2006
  
  Pages: 198-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Sequential Peptide Ligation by Using a Controlled Cysteinyl Prolyl Ester (CPE) Autoactivating Unit2007
- Author(s)
  Toru Kawakami, Saburo Aimoto
- Journal Title
  
  Tetrahedron Lett 48
  
  Pages: 1903-1905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Polypeptide Synthesis via the N-to S-Acyl Shift Reaction2007
- Author(s)
  T. Kawakami
- Journal Title
  
  Peptides 2006
  
  Pages: 198-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Sequential Peptide Ligation by Using a Controlled Cysteinyl Prolyl Ester (CPE) Autoactivating Unit2007
- Author(s)
  Toru Kawakami, Saburo Aimoto
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 1903-1905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Sequential Peptide Ligation by Using a Controlled Cysteinyl Prolyl Ester (CPE) Autoactivating Unit2007
- Author(s)
  Kawakami, T., Aimoto, S.
- Journal Title
  
  Tetrahedron Letters 48(11)
  
  Pages: 1903-1905
- Data Source
  KAKENHI-PROJECT-17750158
[Journal Article] Polypeptide Synthesis via the N- to S-Acyl Shift Reaction2007
- Author(s)
  Toru Kawakami
- Journal Title
  
  Peptides 2006
  
  Pages: 198-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17750158
[Journal Article] Sequential peptide ligation by using a controlled cysteinyl prolyl ester (CPE) autoactivating unit.2007
- Author(s)
  T., Kawakami
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 1903-1905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Peptide Ligation Using a Building Block Having a Cysteinyl Prolyl Ester (CPE) Autoactivating Unit at the Carboxy Terminus2007
- Author(s)
  Toru Kawakami, Saburo Aimoto
- Journal Title
  
  Chem. Lett. 36
  
  Pages: 76-77
- NAID
  10018663050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Peptide Thioester Synthesis via an Auxiliary-Mediated N-S Acyl Shift Reaction in SolutionInt2007
- Author(s)
  Ken'ichiro Nakamura, Hiroaki Mori, Toru Kawakami, Hironobi Hojo, Yoshiaki Nakahara, Saburo Aimoto
- Journal Title
  
  J. Peptide Res. Therapeutics 13
  
  Pages: 191-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Generation of an S-peptide via an N-S acyl shift reaction in a TFA solution2006
- Author(s)
  Nakamura, K., Sumida, M., Kawakami, T., Vorherr, T., Aimoto, S.
- Journal Title
  
  Bulletin of the Chemical Society of Japan 79(11)
  
  Pages: 1773-1780
- Data Source
  KAKENHI-PROJECT-17750158
[Journal Article] Sequential Peptide Ligation by the Combination of the Thioester Method and Extended Chemical Ligation2006
- Author(s)
  T.Kawakami
- Journal Title
  
  Peptide Science 2005 (印刷中)
- Data Source
  KAKENHI-PROJECT-17750158
[Journal Article] Peptide ligation that involves an intramolecular N to S acyl shift reaction.2006
- Author(s)
  Kawakami, T., Nakamura, K., Aimoto, S.
- Journal Title
  
  Peptide Science 2006
  
  Pages: 29-29
- Data Source
  KAKENHI-PROJECT-17750158
[Journal Article] N-S acyl shift reaction on peptide backbone and its application to preparation of peptide thioesters2006
- Author(s)
  Ken'ichiro Nakamura, Toru Kawakami, Hironobu Hojo, Yoshiaki Nakahara, Saburo Aimoto
- Journal Title
  
  Peptide Science 2006 42
- NAID
  10020528860
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Peptide ligation thinvolves an intramolecular N to S acyl shift reaction2006
- Author(s)
  Toru Kawakami, Ken'ichiro Nakamura, Saburo Aimoto
- Journal Title
  
  Peptide Science 2006 29
- Data Source
  KAKENHI-PROJECT-18310145
[Journal Article] Generation of an S-Peptide via an N-S Acyl Shift Reaction in TFA Solution2006
- Author(s)
  K. Nakamura, M. Sumida, T. Kawakami, T. Vorherr, S. Aimoto
- Journal Title
  
  Bull Chem Soc. Jpn. 79
  
  Pages: 1773-1780
- NAID
  10019373528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Sequential peptide chemical ligation by the thioester method and extended chemical ligation2005
- Author(s)
  T.Kawakami
- Journal Title
  
  Tetrahedron Letters 46(33)
  
  Pages: 5533-5536
- Data Source
  KAKENHI-PROJECT-17750158
[Journal Article] Peptide Thioester Preparation Based on an N-S Acyl Shift Reaction Mediated by a Thiol Ligation Auxiliary2005
- Author(s)
  T.Kawakami
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 8805-8807
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Peptide Thioester Preparation Based on an N-S Acyl Shift Reaction Mediated by a Thiol Ligation Auxiliary.2005
- Author(s)
  T. Kawakami,M. Sumida, K. Nakamura, T. Vorherr, S. Aimoto
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 8805-8807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Extended chemical ligation for polypeptide synthesis by using a photoremovable auxiliary2005
- Author(s)
  T.Kawakami
- Journal Title
  
  Peptides 2004
  
  Pages: 226-227
- Data Source
  KAKENHI-PROJECT-17750158
[Journal Article] Extended chemical ligation for polypeptide synthesis by using a photoremovable auxiliary2005
- Author(s)
  T.Kawakami et al.
- Journal Title
  
  Peptide 2004 (印刷中)
- Data Source
  KAKENHI-PROJECT-15750143
[Journal Article] Sequential Peptide Chemical Ligation by the Thioester Method and Extended Chemical Ligation.2005
- Author(s)
  T. Kawakami, M. Tsuchiya, K. Nakamura, S. Aimoto
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 5533-5536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Chemical Ligation Using a Photoremovable Auxiliary2005
- Author(s)
  T.Kawakami et al.
- Journal Title
  
  Peptide Science 2004 (印刷中)
- Data Source
  KAKENHI-PROJECT-15750143
[Journal Article] Peptide Thioester Preparation Based on an N-S Acyl Shift Reaction Mediated by a Thiol Ligation Auxiliary2005
- Author(s)
  T.Kawakami
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 8805-8807
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380287
[Journal Article] Peptide Thioester Preparation Based on an N-S Acyl Shift Reaction Mediated by a Thiol Ligation Auxiliary2005
- Author(s)
  K.Kawakami
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 8805-8807
- Data Source
  KAKENHI-PROJECT-14380287
[Journal Article] Sequential Peptide Chemical Ligation by the Thioester Method and Extended Chemical Ligation2005
- Author(s)
  T.Kawakami
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 5533-5536
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380287
[Journal Article] Sequential Peptide Chemical Ligation by the Thioester Method and Extended Chemical Ligation2005
- Author(s)
  T.Kawakami
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 5533-5536
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Peptide Thioester Preparation Based on an N-S Acyl Shift Reaction Mediated by a Thiol Ligation Auxiliary2005
- Author(s)
  T.Kawakami
- Journal Title
  
  Tetrahedron Letters 46(50)
  
  Pages: 8805-8807
- Data Source
  KAKENHI-PROJECT-17750158
[Journal Article] A photoremovable ligation auxiliary for use in polypeptide synthesis2003
- Author(s)
  Toru Kawakami
- Journal Title
  
  Tetrahedron Lett. 44
  
  Pages: 6059-6061
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380287
[Patent] ペプチドエステル試薬,およびそのライゲーションまたはチオエステル化合物の製造のための使用2006
- Inventor(s)
  川上徹, 相本三郎
- Industrial Property Rights Holder
  大阪大学, 大阪TLO
- Filing Date
  2006-10-12
- Data Source
  KAKENHI-PROJECT-17750158
[Patent] ペプチドエステル試薬,およびそのライゲーションまたチオエステル化合物の製造のための使用2006
- Inventor(s)
  相本三郎、川上徹
- Industrial Property Rights Holder
  相本三郎、川上徹、大阪大学、大阪産業振興機構
- Filing Date
  2006
- Overseas
- Data Source
  KAKENHI-PROJECT-15083204
[Patent] 特許権2005
- Inventor(s)
  川上徹, 相本三郎
- Industrial Property Rights Holder
  大阪大学, 大阪TLO
- Industrial Property Number
  2005-300947
- Filing Date
  2005-10-14
- Data Source
  KAKENHI-PROJECT-17750158
[Patent] ペプチドエステルを用いたライゲーション法、およびチオエステル化合物の製造方法2005
- Inventor(s)
  川上徹、相本三郎
- Industrial Property Rights Holder
  川上徹、相本三郎、大阪大学、大阪産業振興機構
- Filing Date
  2005
- Data Source
  KAKENHI-PROJECT-15083204
[Patent] ペプチドエステルを用いたライゲーション法、およびチオエステル化合物の製造方法2005
- Inventor(s)
  相本三郎, 川上徹
- Industrial Property Rights Holder
  発明者大阪大学大阪産業振興機構
- Filing Date
  2005-10-14
- Data Source
  KAKENHI-PROJECT-15083204
[Presentation] Synthesis of Ubiquitinated Histone H3 and its Effect on DNA Methyltransferase 12021
- Author(s)
  Toru Kawakami
- Organizer
  The 18th Akabori Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] ライゲーション法を基盤とする翻訳後修飾タンパク質の化学合成2021
- Author(s)
  川上　徹
- Organizer
  蛋白質研究所セミナー「多角的な視点による蛋白質修飾の機能解明」
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] Investigation on stereochemistry of cysteinyl prolyl ester (CPE) peptide for the formation of thioester2020
- Author(s)
  Eri Sasakura, Hironobu Hojo, Toru Kawakami
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] Chemical Synthesis of Ubiquitinated Histone H3 and Its Effect on DNA Methyltransferase 12019
- Author(s)
  T. Kawakami, Y. Mishima, M. Takazawa, H. Hojo, I. Suetake
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] ユビキチン化ヒストンH3の化学合成2019
- Author(s)
  川上　徹，高澤雅也，三島優一，北條裕信，末武　勲
- Organizer
  第19回日本蛋白質科学会年会，第71回日本細胞生物学会大会　合同年次大会
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] ユビキチン化ヒストンH3の化学合成とその効果2019
- Author(s)
  川上　徹，三島優一，高澤雅也，北條裕信，末武　勲
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] 修飾ヒストンの化学合成2019
- Author(s)
  川上　徹
- Organizer
  蛋白質研究所セミナー「化学によるタンパク質修飾の機能解明を目指して」
- Invited
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] 修飾ヒストンの化学合成とその応用例2019
- Author(s)
  川上　徹
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] チイランリンカーを用いる蛋白質の簡便なユビキチン化2018
- Author(s)
  川上徹，三島優一，北條裕信，末武勲
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] マルチプルモノユビキチン化ヒストンH3が制御するDNA維持メチル化の構造基盤2018
- Author(s)
  有田恭平、石山怜、西山敦哉、中西真、川上徹、末武勲
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] Chemical synthesis of ubiquitinated histone H32018
- Author(s)
  Toru Kawakami, Masaya Takazawa, Yuichi Mishima, Hironobu Hojo, Isao Suetake
- Organizer
  The 10th international Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] スピンラベルESR法によるヘテロクロマチンタンパク質HP1の動的構造の研究2018
- Author(s)
  荒田敏昭, 三島優一，中澤重顕, 佐藤和信, 工位武治,川上徹,北條裕信, 藤原敏道,宮田真人,末武勳
- Organizer
  第57回電子スピンサイエンス学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] A preparation of isopeptide mimetics by the peptide ligation using a thiirane linker2018
- Author(s)
  Toru Kawakami, Yuichi Mishima, Hironobu Hojo, Isao Suetake
- Organizer
  35th European Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] Chemical Synthesis of Ubiquitinated Histone H32018
- Author(s)
  Kawakami T, Takazawa M, Mishima Y, Hojo H, Suetake I
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] Synthesis of Ubiquitinated Histone2018
- Author(s)
  Toru Kawakami
- Organizer
  The 17th Akabori Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05316
[Presentation] DNAメチル化継承を制御するユビキチン・コード2017
- Author(s)
  西山敦哉、石山玲、佐伯泰、三島優一、川上徹、北條裕信、末武勲、有田恭平、中西真
- Organizer
  第90回　生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] ユビキチン化ヒストンは、維持型メチル化酵素Dnmt1のメチル化維持活性を促進する2017
- Author(s)
  三島優一、川上徹、北條裕信、有田恭平、末武勲
- Organizer
  第90回　生化学会
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] Histone Ubiquitination via an Isopeptide Mimetic Structure by Using a Thiirane Linker2017
- Author(s)
  Toru Kawakami, Yuichi Mishima, Hironobu Hojo, Isao Suetake
- Organizer
  ペプチド学会
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] チイランリンカーを用いるイソペプチド類似構造を介したユビキチン化ヒストンタンパク質の調製2017
- Author(s)
  川上徹，三島優一，北條裕信，末武勲
- Organizer
  2017 年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] チイランリンカーを用いるイソペプチド類似構造を介したヒストンタンパク質のユビキチン化2017
- Author(s)
  川上徹，三島優一，北條裕信，末武勲
- Organizer
  第17回　　蛋白質科学会
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] ユビキチン化ヒストンは、維持型メチル化酵素Dnmt1のメチル化維持活性を促進する2017
- Author(s)
  三島優一，川上徹，北條裕信，有田恭平，末武勲
- Organizer
  2017 年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] チイランリンカーを用いるイソペプチド類似構造を介したユビキチン化ヒストンタンパク質の調製2017
- Author(s)
  川上徹，三島優一，北條裕信，末武勲
- Organizer
  第90回　生化学会
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] HISTONE UBIQUTINATION VIA AN ISOPEPTIDE MIMETIC STRUCTURE BY USING A THIIRANE LINKER2017
- Author(s)
  Kawakami T, Mishima Y, Hojo H, Suetake I
- Organizer
  第54回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] Histone Ubiquitination via an Isopeptide Mimetic Structure by Using a Thiirane Linker2017
- Author(s)
  川上徹，三島優一，北條裕信，末武勲
- Organizer
  第54回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] A preparation of isopeptide mimetics by the peptide ligation using a thiirane linker2016
- Author(s)
  Toru Kawakami, Yuichi Mishima, Misaki Kinoshita, Young-Ho Lee, Isao Suetake
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  石川県立音楽堂（石川県、金沢市）
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] ライゲーション法によるイソペプチド類似構造を介したヒストンペプチドのユビキチン化2016
- Author(s)
  川上徹、三島優一、木下岬、李映昊、末武勲
- Organizer
  第10回エピジェネティクス研究会年会
- Place of Presentation
  千里ライフサイエンスセンター　（大阪府、豊中市）
- Year and Date
  2016-05-09
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] 維持型メチル化酵素Dnmt1のメチル化維持活性は、ヌクレオソーム構造により阻害される2016
- Author(s)
  末武勲、三島優一、川上徹、北條裕信
- Organizer
  第89回生化学会大会
- Place of Presentation
  仙台国際センター　（宮城県　仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] Synthesis of Modified Histone Proteins by CPE Ligation2016
- Author(s)
  T. Kawakami
- Organizer
  The 16th Akabori Conference
- Place of Presentation
  六甲山ホテル（兵庫県神戸市）
- Year and Date
  2016-05-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] チイランリンカーを用いるイソペプチド類似構造を介したヒストンペプチドのユビキチン化2016
- Author(s)
  川上　徹，三島優一，木下　岬，李　映昊，末武　勲
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] Ubiquitination of Histone Peptides via Isopeptide Mimetics by Using a Thiirane Linker2016
- Author(s)
  T. Kawakami, Y. Mishima, M. Kinoshita, Y.-H. Lee, I. Suetake
- Organizer
  第53回ペプチド討論会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] チイランリンカーを用いる急ペプチド類似構造を介したヒストンペプチドのユビキチン化2016
- Author(s)
  川上徹、三島優一、木下岬、李映昊、末武勲
- Organizer
  第89回生化学会大会
- Place of Presentation
  仙台国際センター　（宮城県　仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] チイランリンカーを用いたペプチドライゲーション法によるイソペプチド類似体の合成2016
- Author(s)
  川上　徹，三島優一，木下　岬，李　映昊，末武勲
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] ライゲーション法によるイソペプチド類似構造を介したヒストンペプチドのユビキチン化2016
- Author(s)
  川上　徹，三島優一，木下　岬，李　映昊，末武　勲
- Organizer
  エピジェネティクス研究会　第10回年会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] 維持型DNAメチル化酵素、Dnmt1、のメチル化活性のヌクレオソーム構造による阻害様式2016
- Author(s)
  三島優一、川上徹、北條裕信、末武勲
- Organizer
  第39回分子生物学会
- Place of Presentation
  パシフィコ横浜　（神奈川県　横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] Total chemical synthesis and semi-synthesis of histone proteins by chemical ligation2015
- Author(s)
  Kawakami T and Sueake I
- Organizer
  The 40th Naito Conference organizing committee on “Epigenetics
- Place of Presentation
  シャトレーゼ　ガトーキングダム(札幌)
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] ヒストンの化学合成2015
- Author(s)
  川上　徹
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] 組換えペプチドをC末端側合成ブロックとして用いたライゲーション法によるヒストンH3の合成2015
- Author(s)
  川上　徹・三島優一・北條裕信・田嶋正二・末武　勲
- Organizer
  第9回エピジェネティクス研究会年会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] ヌクレオソーム構造に依存したHP1γのヒストンH3K9me3認識機構2015
- Author(s)
  三島優一、Chanika D Jayasinghe、Kai Lu、川上徹、大谷淳二、木村博信、白川昌宏、Peter Carlton、田嶋正二、末武勲
- Organizer
  第9回エピジェネティクス研究会年会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] Synthesis of modified histone proteins by CPE ligation using a recombinant ｐeptide2015
- Author(s)
  T. Kawakami, R. Yoshikawa, Y. Fujiyoshi, Y. Mishima, H. Hojo, S. Tajima, I. Suetake
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚中央公民館（神奈川県平塚市）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] Synthesis of modified histone proteins by CPE ligation using a recombinant peptide2015
- Author(s)
  T. Kawakami, R. Yoshikawa, Y. Fujiyoshi, Y. Mishima, H. Hojo, S. Tajima, I. Suetake
- Organizer
  7th International Peptide Symposium
- Place of Presentation
  Singapore (Singapore)
- Year and Date
  2015-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05565
[Presentation] ライゲーション法において発現ペプチドを合成ブロックとして用いるためのフェナシル基のチオール保護基としての可能性2015
- Author(s)
  川上　徹，北條裕信
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  千葉県船橋市　日本大学
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] SYNTHESIS OF MODIFIED HISTONE PROTEINS BY CPE LIGATION USING A RECOMBINANT PEPTIDE2015
- Author(s)
  Kawakami　T,Yoshikawa　R, Fujiyoshi　Y, Mishima　Y, Hojo　H, Tajima　S, Suetake　I
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚中央公民館（神奈川）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] Methods for Peptide Thioester Preparation2015
- Author(s)
  Toru Kawakami
- Organizer
  7th Annual AsiaTIDE
- Place of Presentation
  大阪府大阪市　ハイアットリージェンシー大阪
- Year and Date
  2015-03-04
- Invited
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] SYNTHESIS OF MODIFIED HISTONE PROTEINS BY CPE LIGATION USING A RECOMBINANT PEPTIDE2015
- Author(s)
  Kawakami T, Yoshikawa R, Fujiyoshi Y, Mishima Y, Hojo H, Tajima S, Suetake I
- Organizer
  The 7th International Peptide Symposiuｍ
- Place of Presentation
  biopolis （シンガポール）
- Year and Date
  2015-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14418
[Presentation] Synthesis of modified histones by the use of CPE chemistry2014
- Author(s)
  Toru Kawakami
- Organizer
  The 15th Akabori Conference
- Place of Presentation
  ドイツ　ボッパード　　ベストウエスティン
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] 発現ペプチドをライゲーション法の合成ブロックとして用いるためのフェナシル基のチオール保護基としての可能性2014
- Author(s)
  川上　徹，北條裕信
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島県徳島市　徳島大学
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] Synthesis of Histone by the Use of Cys-Pro Ester (CPE) Ligation2014
- Author(s)
  Toru Kawakami, Ryo Yoshikawa, Yuki Fujiyoshi, Hironobu Hojo, Shoji Tajima, Isao Suetake
- Organizer
  33th European Peptide Symposium
- Place of Presentation
  ブルガリア　ソフィア　国立文化宮殿
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] Rate Enhancement of Conversion of Peptide Cys-Pro ester to Peptide Thioester by the Structural Modifications2013
- Author(s)
  T. Kawakami, A. Kamauchi, E. Harada, S. Aimoto
- Organizer
  4th Modern Solid Phase Peptide Synthesis & Its Applications Symposium
- Place of Presentation
  Hotel Maiko Villa Kobe, Kobe
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] Total Chemical Synthesis and Semi-synthesis of Histone H3 and H4 by the Use of Cys-Pro Ester Auto-activating Unit for the Thioester Precursor2013
- Author(s)
  T. Kawakami, Y. Akai, R. Yoshikawa, I. Suetake, S. Tajima, S. Aimoto
- Organizer
  5th Asia-Pacific International Peptide Symposium
- Place of Presentation
  Hotel Hankyu Expopark, Suita
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] Protein synthesis by chemical ligation base on the use of a peptide-Cys-Pro ester as a peptide thioester precursor2013
- Author(s)
  T. Kawakami, S. Aimoto
- Organizer
  International Scientific Conference on “Chemistry - Opportunity and Development” 35th Anniversary of the Institute of Chemistry
- Place of Presentation
  The Institute of Chemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam
- Invited
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] ケミカルライゲーションによる修飾ヒストン合成法の開発：H4K20meの合成とテトラソームの再構成2013
- Author(s)
  川上　徹，吉川　諒，相本三郎，田嶋正二，末武　勲
- Organizer
  エピジェネティクス研究会　第７回年会
- Place of Presentation
  奈良県新公会堂，奈良
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] Synthesis of Histone H3 by Chemical Ligation2013
- Author(s)
  T. Kawakami
- Organizer
  The 8th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-8)
- Place of Presentation
  Grand Cube, Osaka
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] Chemical Protein Synthesis by the Ligation Based on the Use of an N to S Acyl Shift Reaction2013
- Author(s)
  T. Kawakami
- Organizer
  17th Korean Peptide and Protein Symposium
- Place of Presentation
  Seoul National University, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] 改良型CPE自発的活性化ユニットによるペプチドチオエステル形成2012
- Author(s)
  鎌内彬貴, 川上徹, 相本三郎
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応大学,横浜
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] チオエステルライゲーション法による蛋白質合成:システイン残基でのN-Sアシル基転位反応を経由するペプチドチオエステル形成2011
- Author(s)
  川上徹, 清水咲子, 相本三郎
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  ホテル阪急エキスポパーク,吹田
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Cys-Proエステル(CPE)自己活性化ユニットの改良によるペプチドチオエステル調製法の効率化2011
- Author(s)
  鎌内彬貴, 川上徹, 相本三郎
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学,横浜
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] CPE自己活性化ユニットを用いたリポソーム内でのチオエステル形成2011
- Author(s)
  假屋園大和, 川上徹, 相本三郎
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学,横浜
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Synthesis of peptide thioesters by the use of an N-S acyl shift reaction for peptide ligation2011
- Author(s)
  川上徹
- Organizer
  第14回ペプチドフォーラム
- Place of Presentation
  鹿児島大学,鹿児島
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] ライゲーション法による長鎖ペプチド合成: N-Sアシル基転位反応を基盤とするペプチドチオエステル合成ブロックの合成法を中心に2011
- Author(s)
  川上徹
- Organizer
  第5回プロセス化学ラウンジ
- Place of Presentation
  琵琶レイクオーツカ,大津
- Year and Date
  2011-02-03
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] ライゲーション法による長鎖ペプチド合成:N-Sアシル基転位反応を基盤とするペプチドチオエステル合成ブロックの合成法を中心に2011
- Author(s)
  川上徹
- Organizer
  第5回プロセス化学ラウンジ
- Place of Presentation
  琵琶レイクオーツカ大津
- Year and Date
  2011-02-03
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Formation of peptide thioesters by the use of modified Cys-Pro Ester(CPE) autoactivating unit2011
- Author(s)
  A. Kamauchi, E. Harada, S. Aimoto, T. Kawakami
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌コンベンションセンター,札幌
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Formation of peptide thioesters by the use of modified Cys-Pro Ester (CPE) autoactivating unit2011
- Author(s)
  A.Kamauchi, E.Harada, S.Aimoto, T.Kawakami
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌コンベンションセンター,札幌
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Peptide ligation via thioester formation at the cysteine residue2010
- Author(s)
  T. Kawakami, S. Aimoto
- Organizer
  5^<th> International Peptide Symposium
- Place of Presentation
  京都国際会議場,京都
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Peptide Diketopiperazine-Thioester Formation via an N-S Acyl Shift Reaction at the Amide Bond between -Xaa-Cys- in the -Xaa-Cys-Pro-Cys- Sequence2010
- Author(s)
  T.Kawakami, S.Shimizu, S.Aimoto
- Organizer
  The 13th Akabori Conference
- Place of Presentation
  Leipzig
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] 2-ニトロベンジルカルバメイト型光分解リンカーを用いる化学合成ペプチドの精製2010
- Author(s)
  原利明、田結荘明、川上徹、相本三郎
- Organizer
  日本化学会第90回春季年会
- Place of Presentation
  近畿大学、東大阪市
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptide Diketopiperazine-thioester formation via an N-S acyl shift reaction at the amide bond between-Xaa-Cys-in the-Xaa-Cys-Pro-Cys-sequence2010
- Author(s)
  T. Kawakami, S. Shimizu, S. Aimoto
- Organizer
  The 13th Akabori Conference
- Place of Presentation
  Leipzig
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Peptide ligation via thioester formation at the cysteine residue2010
- Author(s)
  T.Kawakami, S.Aimoto
- Organizer
  5^<th> International Peptide Symposium
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Cys-Pro-Cys部位におけるN-Sアシル基転位反応を利用したペプチドチオエステルの合成2010
- Author(s)
  清水咲子, 相本三郎, 川上徹
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学, 東大阪
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Cys-Pro-Cys部位におけるN-Sアシル基転位反応を利用したペプチドチオエステルの合成2010
- Author(s)
  清水咲子、相本三郎、川上徹
- Organizer
  日本化学会第90回春季年会
- Place of Presentation
  近畿大学、東大阪市
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptide Diketopiperazine Thioester Formation at the Cys-Pro-Cys Position2010
- Author(s)
  T.Kawakami, S.Shimizu, S.Aimoto
- Organizer
  31st European Peptide Symposium
- Place of Presentation
  Copenhagen
- Year and Date
  2010-09-06
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Cys-Pro-Cys部位におけるN-Sアシル基転位反応を利用したペプチドチオエステルの合成2010
- Author(s)
  清水咲子, 相本三郎, 川上徹
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学,東大阪
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Histone H3K9 trimethylation stimulates the histone H3K27 methylation activity of PRC2 bypassing Eed2010
- Author(s)
  Isao Suetake, Saburo Aimoto, Yuko Aoki, Kyoichi Isono, Toru Kawakami, Hiroshi Kimura, Akihiko Koseki, Yuichi Mishima; Osamu Nishimura, Shoji Tajima, Makoto Watanabe
- Organizer
  Keystone symposium
- Place of Presentation
  Sagebrush Inn and Conference Center, Taos, New Mexico
- Year and Date
  2010-01-20
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptide diketopiperazine thioester formation at the Cys-Pro-Cys position2010
- Author(s)
  T. Kawakami, S. Shimizu, S. Aimoto
- Organizer
  31st European Peptide Symposium
- Place of Presentation
  Copenhagen
- Year and Date
  2010-09-06
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Synthesis of Peptide Thioesters Based on an N to S Acyl Shift Reaction2009
- Author(s)
  Toru Kawakami, Sakiko Shimizu, Saburo Aimoto
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州国際会議場、北九州市
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Synthesis of peptide thioester based on N to S acyl shift reaction2009
- Author(s)
  T. Kawakami, S. Shimizu, S., Aimoto
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州国際会議場,北九州
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Formation of Peptide Thioesters by an N to S Acyl Shift Reaction at the Cysteinyl Prolyl Cysteine Position2009
- Author(s)
  S.Shimizu, T.Kawakami, S., Aimoto
- Organizer
  第44回ペプチド討論会
- Place of Presentation
  北九州国際会議場, 北九州
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Formation of peptide thioesters by an N to S acyl shift reaction at the cysteinyl prolyl cysteine position2009
- Author(s)
  S. Shimizu, T. Kawakami, S., Aimoto
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州国際会議場,北九州
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] ポリコーム群蛋白質複合体PRC2によるH3K27メチル化の新たな活性調節機構2009
- Author(s)
  三島優一、磯野協一、青木優子、川上徹、渡辺真、木村宏、西村紀、相本三郎、古関明彦、田嶋正二、末武勲
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptide Ligation based on an N to S Acyl Shift Reaction2009
- Author(s)
  T.Kawakami, S.Aimoto
- Organizer
  ICCEOCA-4
- Place of Presentation
  Chulabhorn Research Institute, Bangkok, Thailand
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] メチルチオ基をチオール保護基として用いるネイティブケミカルライゲーション法とチオエステル法による連続ライゲーション法2009
- Author(s)
  赤井優一、早稲田真澄、青木優子、竹村梨沙、川上徹、相本三郎
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  千葉
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptide thioester formation and ligation using a cysteinyl prolyl ester(CPE) autoactivating unit2009
- Author(s)
  T. Kawakami, S. Aimoto
- Organizer
  21th American Peptide Symposium
- Place of Presentation
  Broomington
- Year and Date
  2009-06-09
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Synthesis of Peptide Thioester Based on N to S Acyl Shift Reaction2009
- Author(s)
  T.Kawakami, S.Shimizu, S., Aimoto
- Organizer
  第44回ペプチド討論会
- Place of Presentation
  北九州国際会議場, 北九州
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] Formation of Peptide Thioesters by an N to S Acyl Shift Reaction at the Cysteinyl Prolyl Cysteine Position2009
- Author(s)
  Sakiko Shimizu, Saburo Aimoto, Toru Kawakami
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州国際会議場、北九州市
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptide ligation based on an N to S acyl shift reaction2009
- Author(s)
  T. Kawakami, S. Aimoto
- Organizer
  ICCEOCA-4
- Place of Presentation
  Bangkok
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21550155
[Presentation] アミノオキシ基とイソチオシアネート基の選択的化学反応とそれに続くエドマン分解を利用したペプチドの精製2008
- Author(s)
  田結荘明、原利明、中村健一郎、川上徹、相本三郎
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] ネイティブケミカルライゲーション法とチオエステル法の併用を可能にするチオール保護基としてのメチルチオ基の利用2008
- Author(s)
  赤井優一、竹村梨沙、青木優子、早稲田真澄、川上徹、相本三郎
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptide thioester preparation and peptide ligation using cysteinyl prolyl ester (CPE) autoactivating unit2008
- Author(s)
  Toru Kawakami
- Organizer
  30th European Peptide Symposium
- Place of Presentation
  ヘルシンキ
- Year and Date
  2008-09-01
- Data Source
  KAKENHI-PROJECT-15083204
[Presentation] α-ケトアシル基の形成と切断を鍵反応とするペプチド精製法の開発2008
- Author(s)
  原利明、田結荘明、藤本大樹、川上徹、相本三郎
- Organizer
  日本化学会第88春季年会
- Place of Presentation
  東京
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptide thioester preparation and peptide ligation using cysteinyl prolyl ester (CPE) autoactivating unit2008
- Author(s)
  Toru Kawakami
- Organizer
  3oth European Peptide Symposium
- Place of Presentation
  ヘルシンキ
- Year and Date
  2008-09-01
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptide thioester preparation and peptide ligation using cysteinyl prolyl ester(CPE)autoactivating unit2008
- Author(s)
  Toru Kawakami
- Organizer
  3oth European Peptide Symposium
- Place of Presentation
  ヘルシンキ
- Year and Date
  2008-09-01
- Data Source
  KAKENHI-PROJECT-15083204
[Presentation] Synthesis of Peptide Thioester by the Cysteinyl Prolyl Ester (CPE) Method2008
- Author(s)
  Toru Kawakami, Saburo Aimoto
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] ペプチドCys-Proエステルを合成ブロックとして用いるトリメチルリシン含有ヒストンH3合成法の研究2008
- Author(s)
  赤井優一、藤本久雄、竹村梨沙、田結荘明、喜多知恵子、神田仁美、川上徹、相本三郎
- Organizer
  日本化学会第88春季年会
- Place of Presentation
  東京
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Fmoc-アミノプロピルオキシ基を導入した2-ニトロベンジルカルバメイト型リンカーの合成とペプチド精製への応用2008
- Author(s)
  原利明、田結荘明、川上徹、相本三郎
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Synthesis of Peptide Thioester by the Cysteinyl Prolyl Ester(CPE)Method2008
- Author(s)
  Toru Kawakami
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-15083204
[Presentation] Peptide Ligation via the In-Situ Transformation of an Amide into a Thioester at a Cysteine Residue2007
- Author(s)
  Toru Kawakami, Saburo Aimoto
- Organizer
  20th American Peptide Society Symposium
- Place of Presentation
  カナダ・モントリオール
- Year and Date
  2007-06-27
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptied Ligation via the In-situ Transformation of an Amide in to a Thioester at a Cysteine Residue2007
- Author(s)
  T., Kawakami
- Organizer
  American Peptied Symposium
- Place of Presentation
  カナダ・モントリオール
- Year and Date
  2007-06-27
- Data Source
  KAKENHI-PROJECT-15083204
[Presentation] N to S Acyl Shift Reaction in Peptide Ligation2007
- Author(s)
  Toru Kawakami
- Organizer
  4th international Peptide Symposium
- Place of Presentation
  オーストラリア・ケアンズ
- Year and Date
  2007-10-23
- Data Source
  KAKENHI-PROJECT-17750158
[Presentation] N to S Acyl Shift Reaction in Peptide Ligation2007
- Author(s)
  Toru Kawakami, Ken'ichiroh Nakamura, Hisao Fujimoto, Saburo Aimoto
- Organizer
  4th international Peptide Symposium
- Place of Presentation
  ーストラリア・ケアンズ
- Year and Date
  2007-10-23
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptide Ligation via the N to S Acyl Shift Reaction2007
- Author(s)
  oru Kawakami, Saburo Aimoto
- Organizer
  Chemical Protein Synthesis Meeting
- Place of Presentation
  オーストラリア・ヘロン島
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] 部位特異的に修飾されたヒストンH3部分配列の合成2007
- Author(s)
  藤本久雄、喜多千恵子、田結荘明、赤井優一、竹村梨沙、神田仁美、川上徹、相本三郎
- Organizer
  第44回ペプチド討論会
- Place of Presentation
  富山市
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] Peptied Ligation via the N to S Acyl Shift Reaction2007
- Author(s)
  T., Kawakami
- Organizer
  Chemical Protein Synthesis Meeting
- Place of Presentation
  オーストラリア・ヘロン島
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-15083204
[Presentation] Peptide Ligation via the In-Situ Transformation of an Amide into a Thioester at a Cysteine Residue2007
- Author(s)
  Toru Kawakami
- Organizer
  20th American Peptide Society Symposium
- Place of Presentation
  カナダ・モントリオール
- Year and Date
  2007-06-27
- Data Source
  KAKENHI-PROJECT-17750158
[Presentation] N to S Acyl Shift Reaction in Peptide Ligation2007
- Author(s)
  T. Kawakami
- Organizer
  4th international Peptide Symposium
- Place of Presentation
  オーストラリア・ケアンズ
- Year and Date
  2007-10-23
- Data Source
  KAKENHI-PROJECT-18310145
[Presentation] N to S Acyl Shift Reaction in Peptied Ligation2007
- Author(s)
  T., Kawakami
- Organizer
  4th international Peptied Symposium
- Place of Presentation
  オーストラリア・ケアンズ
- Year and Date
  2007-10-23
- Data Source
  KAKENHI-PROJECT-15083204
[Presentation] Peptide Ligation via the N to S Acyl Shift Reaction2007
- Author(s)
  Toru Kawakami
- Organizer
  Chemical Protein Synthesis Meeting
- Place of Presentation
  オーストラリア・ヘロン島
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-17750158
[Presentation] Cys-Proエステル法とチオエステル法の連続ライゲーション：ヒストンH3の合成
- Author(s)
  川上　徹，赤井優一，藤本久雄，喜多千恵子，竹村梨沙，青木裕子，早稲田真澄，相本三郎
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島県民交流センター
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] Peptide thioester formation at a Cys residue via an N-S acyl shift reaction
- Author(s)
  Toru Kawakami, Akitaka Kamauchi, Saburo Aimoto
- Organizer
  The 14th Akabori Conference
- Place of Presentation
  北海道ニセコ町民センター
- Data Source
  KAKENHI-PROJECT-24550187
[Presentation] 自発的活性化ユニットCys-Proエステルを用いる連続ライゲーションによるヒストンH3の合成
- Author(s)
  川上　徹・赤井優一・藤本久雄・喜多千恵子・竹村梨沙・青木優子・早稲田真澄・相本三郎
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  滋賀県草津市　立命館大学びわこ・くさつキャンパス
- Data Source
  KAKENHI-PROJECT-24550187

1. AIMOTO Saburo (80029967)

# of Collaborated Projects: 5 results

# of Collaborated Products: 42 results
2. SUETAKE Isao (80304054)

# of Collaborated Projects: 4 results

# of Collaborated Products: 36 results
3. TAJIMA Shoji (50132931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. NAGAO Kohjiro (40587325)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SATO Takeshi (90403013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. HIRAKI Yuji (40144498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SAITO Hiroyuki (60300919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. BABA Teruhiko (40357794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KASHIWAMURA Shinichiro (00185761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OKAMURA Haruki (60111043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. AKAJI Kenichi (60142296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 北條裕信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAKAMI Toru 川上 徹

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Synthesis of modified histones and its use for preparation of asymmetric nucleosomesPrincipal Investigator

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Synthesis of histone protein for the post-translationally modified protein libraryPrincipal Investigator

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Development of a method for protein labeling by the use of intramolecular thioester-forming unitPrincipal Investigator

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Development of a new method for peptide ligation based on the N-S acyl shift reactionPrincipal Investigator

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新規ペプチドライゲーション法の開発とそれを用いる膜蛋白質合成Principal Investigator

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膜貫通型蛋白質の合成を目的とする新規なペプチドライゲーション法の開発Principal Investigator

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発現蛋白質を合成ブロックとして用いる高純度長鎖ペプチド合成法の開発Principal Investigator

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KAWAKAMI Toru 川上徹