Ashihara Eishi 芦原英司

… Alternative Names

ASHIHARA Eishi 芦原英司

芦原英司アシハラエイシ

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Researcher Number	70275197
Other IDs
Affiliation (Current)	2025: 京都薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 京都薬科大学, 薬学部, 教授 2012 – 2021: 京都薬科大学, 薬学部, 教授 2012: 京都府立医科大学, 医学(系)研究科, 講師 2011 – 2012: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2010 – 2011: 京都府立医科大学, 医学研究科, 講師 … More 2010: Kyoto University, 医学研究科, 講師 2010: 京都府立医科大学, 大学院・医学研究科, 講師 2007 – 2009: Kyoto University, Dep. of Transfusion Mediene and Cell Therapy, Assistant Professor 2008: 京都大学, 大学院・医学研究科, 助教 2005 – 2006: 京都大学, 医学研究科, 助手 1998 – 1999: 京都府立医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related / Hematology Except Principal Investigator Hematology / Orthopaedic surgery / Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 37010:Bio-related chemistry / Urology / Collagenous pathology/Allergology / General physiology / Laboratory medicine
Keywords	Principal Investigator 多発性骨髄腫 / 急性リンパ芽球性白血病 / TGF-β / 低酸素環境 / がん幹細胞 / 骨髄微小環境 / ドラッグリポジショニング / がん分子標的治療薬 / 公共データベース / がん分子標的治療 … More / エクソソーム / ドラッグデリバリーシステム / 造血器腫瘍 / 抗体薬物複合体 / 核酸医薬 / CD63 / エクソゾーム / C7orf24 / がん微小環境 / 低酸素 / 分子標的 / RNA干渉 / CD138 / β-catenin / siRNA / FLT-3 ligand / 樹状細胞 / CD34陽性細胞 / 末梢血幹細胞 … More Except Principal Investigator 骨肉腫 / γδT細胞 / ABL / Ras / ビスホスホネート / 軟部肉腫 / 破骨細胞 / 分子標的治療 / 慢性骨髄性白血病 / アポトーシス / 白血病 / セスキテルペンラクトン / ゲラニルカルバゾール / 遺伝子発現解析 / 生合成 / がん幹細胞 / 擬天然物 / 薬用植物由来酵素 / 膠芽腫幹細胞 / 生合成中間体 / 膠芽腫治療薬 / 擬天然型化合物 / 植物酵素 / 転移 / 癌 / DDS / anti-miR / ハイジャック / 抗体 / non-coding RNA / 抗体結合型核酸 / 核酸医薬 / microRNA / エクソソーム / 膀胱癌注入療法 / 複合免疫療法 / MICA/B / γδＴ細胞 / 正所性膀胱癌モデル / 膀胱注入療法 / 膀胱癌 / Niche / γδTcell / osteoclast / leukemia / bisphosphonate / ナノチャンバー / γδ T細胞 / ニッチ / ビスフォスフォネート / 超音波 / parathyroid Hormone / 徐放 / ハイドロキシアパタイト / 骨セメント / 転移性骨腫瘍 / MDSCs / コラーゲン誘導関節炎 / MSDCs / 骨髄由来抑制細胞 / 関節リウマチ / エクソゾーム / がん免疫 / 細胞内小器官 / 骨肉種 / マクロファージ / 免疫療法 / エキソゾーム / 微粒子 / 光線力学的治療法 / アクリジンオレンジ / 放射線治療 / ビスホスフォネート / Glyoxalase-I / T315I遺伝子 / オーロラキナーゼ阻害剤 / チロシンキナーゼ阻害剤 / 白血病幹細胞 / 低酸素環境 / 低酸素 / 慢性骨髄白血病 / 治療抵抗性 / 幹細胞 / 腎皮質集合管 / アルドステロン / 透浸圧 / ナトリウム輸送 / 高血圧 / トラッフィッキング / 浸透圧 / プロテアーゼ阻害剤 / 皮質集合管 / アルデステン / ENaC / 分子標的療法 / フィラデルフィア染色体 / イマチニブ耐性 / Lyn / Bcr-Abl / 点突然変異 / 中枢神経性白血病 / NS-187 / BCR-ABL / 耐性 / Bafetinib / Imatinib / BCR-ABL分子標的治療 / 遺伝子変異 / パフェチニブ / INNO-406 / イマチニブ / 抗HLA抗体 / 抗顆粒球抗体 / 輸血後関連急性肺障害 / ABO血液型抗体 / 輸血検査 / 表面プラズモン共鳴 / p53 / カスパーゼ / クマリン / GUT-70 / 天然化合物 / 3環系クマリン / おとぎり草 / 分子標的治療薬 Less

Identification of novel target molecules against ALL and discovery of their seed compounds using open access dataPrincipal Investigator
- Principal Investigator
  
  芦原英司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Pharmaceutical University
Construction of pseudo-natural products using enzymes from medicinal plants and development of therapeutic agents for glioblastoma
- Principal Investigator
  
  中村誠宏
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kyoto Pharmaceutical University
Development of exosome-capturing antibody-conjugated nucleic acid medicines against multiple myelomaPrincipal Investigator
- Principal Investigator
  
  Ashihara Eishi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Pharmaceutical University
Novel targeting system of circulating non-coding RNAs for the inhibition of cancer metastasis
- Principal Investigator
  
  YAMAYOSHI Asako
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Nagasaki University
Development of intravesical human gdT cell based immunotherapy against urinary bladder cancer cell
- Principal Investigator
  
  Nakanishi Hiyoyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kyoto Prefectural University of Medicine
Development of a novel therapy against myeloma stem cells in a bone marrow hypoxic nichePrincipal Investigator
- Principal Investigator
  
  Ashihara Eishi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Pharmaceutical University
Development of non-operative treatment for local control and new bone formation against metastatic bone tumors
- Principal Investigator
  
  MURATA Hiroaki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
The analysis of myeloid-derived suppressor cells related with the pathogenesis of rheumatoid arthritis and development of a new therapy
- Principal Investigator
  
  KAWAHITO YUTAKA
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Kyoto Prefectural University of Medicine
Analysis of myeloma stem cells and their nichePrincipal Investigator
- Principal Investigator
  
  ASHIHARA Eishi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Pharmaceutical University
  Kyoto Prefectural University of Medicine
Development of new treatments against malignant bone and soft tissue tumors by using bisphosphonate and ionizing radiation
- Principal Investigator
  
  MURATA Hiroaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Challenging study of immunotherapy for osteosarcoma usingmicroparticles induced by photodynamic therapy
- Principal Investigator
  
  KUSUZAKI Katsuyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Heian Jogakuin(St.Agnes')University
Eradication of chronic myelogenous leukemia stem cells and abnormal clone with T315I point mutation
- Principal Investigator
  
  MAEKAWA Taira
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Regulation of intracellular localization of ENaC by protease
- Principal Investigator
  
  MARUNAKA Yoshinori
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kyoto Prefectural University of Medicine
Development of antibody-conjugatedβ-catenin siRNA therapy against multiple myelomaPrincipal Investigator
- Principal Investigator
  
  ASHIHARA Eishi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Molecular therapeutics for imatinib-resistant Ph-positive leukemias with newly developed Bcr-Abl/Lyn tyrosine kinase inhibitor
- Principal Investigator
  
  MAEKAWA Taira
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Development ofa novel therapy for leukemia utilizing bisphcephonate triangle
- Principal Investigator
  
  KIMURA Shinya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
表面プラズモン共鳴による革新的な輸血関連検査法の開発
- Principal Investigator
  
  木村晋也
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
ブラジル・おとぎり草から抽出した新規天然有機化合物(GUT-70)の抗腫瘍効果
- Principal Investigator
  
  MAEKAWA Taira
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
末梢血幹細胞中の樹状細胞の誘導とその機能に関する研究Principal Investigator
- Principal Investigator
  
  芦原英司
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine

[Book] ナーシング・グラフィカ　健康の回復と看護⑦　疾病と治療2020
- Author(s)
  芦原英司
- Total Pages
  358
- Publisher
  メディカ出版
- ISBN
  9784840461306
- Data Source
  KAKENHI-PROJECT-19K08826
[Book] Wntシグナル経路を標的とした骨髄腫治療薬開発．日本臨床　増刊号　多発性骨髄腫学―最新の診療と基礎研究―2016
- Author(s)
  芦原英司
- Total Pages
  7
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26461436
[Book] 多発性骨髄腫Updating.第4巻移植適応骨髄腫の治療.新規薬剤時代における移植適応患者の治療戦略2013
- Author(s)
  芦原英司
- Total Pages
  203
- Publisher
  医療ジャーナル社
- Data Source
  KAKENHI-PROJECT-23591404
[Book] Nmerging Trends in Cell and Gene Therapy2013
- Author(s)
  Ashihara E, Maekawa T
- Total Pages
  705
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23591404
[Book] RNA Interference for Oncology: Clinical Prospects Beyond the Hype. In: Emerging Trends in Cell and Gene Therapy.2013
- Author(s)
  Ashihara E, Maekawa T.
- Total Pages
  705
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23591404
[Book] 多発性骨髄腫　Updating．第4巻　移植適応骨髄腫の治療．~新規薬剤時代における移植適応患者の治療戦略~2013
- Author(s)
  芦原英司．
- Total Pages
  203
- Publisher
  医療ジャーナル社
- Data Source
  KAKENHI-PROJECT-23591404
[Book] In Sarcoma Edited by Bulter EJ: Nova Science Publisher Inc.2012
- Author(s)
  Kusuzaki K, Ashihara E, Hosogi S, Matsubara T, Satonaka H, Manamura T, Matsumine A, Murata H, Sudo A, Uchida A, Murata H, Baldini N, Fais S, Marunaka Y.
- Total Pages
  5
- Publisher
  New concept of limb salvage surgery in musculoskeletal sarcomas with acridine orange therapy
- Data Source
  KAKENHI-PROJECT-23659730
[Book] RAN医学・医療―新たな診断・治療を拓く―2011
- Author(s)
  芦原英司、前川平
- Total Pages
  608
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-23591404
[Book] RAN医学・医療―新たな診断・治療を拓く―2011
- Author(s)
  芦原英司、前川　平
- Total Pages
  608
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-23591404
[Book] 最新RNAと疾患研究2009.2009
- Author(s)
  芦原英司
- Total Pages
  206
- Publisher
  メディカルドウ
- Data Source
  KAKENHI-PROJECT-20591121
[Book] 遺伝子MOOK15最新RNAと疾患研究2009
- Author(s)
  芦原英司、前川平
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-20591121
[Book] 最新RNAと疾患研究20092009
- Author(s)
  芦原英司
- Total Pages
  206
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-21390293
[Book] BLOOD MASTER-血液疾患症例に学ぶ-2008
- Author(s)
  芦原英司
- Total Pages
  12
- Publisher
  インターメディカ
- Data Source
  KAKENHI-PROJECT-20591121
[Book] がんの分子標的治療(鶴尾隆)(編集)(シグナル伝達系阻害剤)2008
- Author(s)
  前川平、芦原英司、木村晋也
- Publisher
  南山堂、東京
- Data Source
  KAKENHI-PROJECT-18390283
[Book] ナーシング・グラフィカ2008
- Author(s)
  芦原英司
- Total Pages
  5
- Publisher
  イーエックス
- Data Source
  KAKENHI-PROJECT-20591121
[Book] ゾレドロン酸のEBM2006
- Author(s)
  芦原英司
- Total Pages
  13
- Publisher
  メディカルレビュー社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Journal Article] Expression level of BTN3A1 on the surface of CD14+ monocytes is a potential predictor of γδ T cell expansion efficiency2022
- Author(s)
  Tomogane Mako、Omura Maho、Sano Yusuke、Shimizu Daiki、Toda Yuki、Hosogi Shigekuni、Kimura Shinya、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 588 Pages: 47-54
- DOI
  10.1016/j.bbrc.2021.12.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20K17388
[Journal Article] The CDK4/6-UCHL5-BRD4 axis confers resistance to BET inhibitors in MLL-rearranged leukemia cells by suppressing BRD4 protein degradation2022
- Author(s)
  Amari Keigo、Sasagawa Satoru、Imayoshi Natsuki、Toda Yuki、Hosogi Shigekuni、Imamura Toshihiko、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 588 Pages: 147-153
- DOI
  10.1016/j.bbrc.2021.12.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20J22374, KAKENHI-PROJECT-20K17388
[Journal Article] Successful Incorporation of Exosome-Capturing Antibody-siRNA Complexes into Multiple Myeloma Cells and Suppression of Targeted mRNA Transcripts2022
- Author(s)
  Soma Emi、Yamayoshi Asako、Toda Yuki、Mishima Yuji、Hosogi Shigekuni、Ashihara Eishi
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 3 Pages: 566-566
- DOI
  10.3390/cancers14030566
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PLANNED-20H05874, KAKENHI-PROJECT-20K17388
[Journal Article] CN470 is a BET/CBP/p300 multi-bromodomain inhibitor and has an anti-tumor activity against MLL-rearranged acute lymphoblastic leukemia2022
- Author(s)
  Imayoshi Natsuki、Yoshioka Makoto、Tanaka Kuniaki、Yang Shyh-Ming、Akahane Koshi、Toda Yuki、Hosogi Shigekuni、Inukai Takeshi、Okada Seiji、Maloney David J.、Nakahata Tatsutoshi、Takita Junko、Kato Itaru、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 590 Pages: 49-54
- DOI
  10.1016/j.bbrc.2021.12.078
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20J22374, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-20K17388, KAKENHI-PROJECT-23K24298
[Journal Article] CG223, a novel BET inhibitor, exerts TGF-β1-mediated antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis2021
- Author(s)
  Kaneshita Shunya、Kida Takashi、Yoshioka Makoto、Nishioka Keisuke、Raje Mithun、Sakashita Aki、Hirano Aiko、Sagawa Tomoya、Kasahara Akiko、Inoue Takuya、Fujioka Kazuki、Nagahara Hidetake、Wada Makoto、Kohno Masataka、Strovel Jeffrey W.、Fletcher Steven、Ashihara Eishi、Kawahito Yutaka
- Journal Title
  
  Pulmonary Pharmacology & Therapeutics
  
  Volume: 70 Pages: 102057-102057
- DOI
  10.1016/j.pupt.2021.102057
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Journal Article] A novel dipeptide type inhibitor of the Wnt/b-catenin pathway suppresses proliferation of acute myelogenous leukemia cells.2021
- Author(s)
  Ryosuke Wakabayashi, Yasunao Hattori, Shigekuni Hosogi, Yuki Toda, Kazuyuki Takata, Eishi Ashihara.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 535 Pages: 73-79
- DOI
  10.1016/j.bbrc.2020.12.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20K17388
[Journal Article] Human Vγ9Vδ2?T cells exert anti-tumor activity independently of PD-L1 expression in tumor cells2021
- Author(s)
  Tomogane Mako、Sano Yusuke、Shimizu Daiki、Shimizu Teruki、Miyashita Masatsugu、Toda Yuki、Hosogi Shigekuni、Tanaka Yoshimasa、Kimura Shinya、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 573 Pages: 132-139
- DOI
  10.1016/j.bbrc.2021.08.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20K17388, KAKENHI-PROJECT-20K18123
[Journal Article] Factors Associated with Dose Modification of Lenalidomide Plus Dexamethasone Therapy in Multiple Myeloma2020
- Author(s)
  Yoko Kado, Masayuki Tsujimoto, Shin-ichi Fuchida, Akira Okano, Mayumi Hatsuse, Satoshi Murakami, Hikofumi Sugii, Kumi Ueda, Yuki Toda, Tetsuya Minegaki, Kohshi Nishiguchi, Yuichi Muraki, Chihiro Shimazaki, Eishi Ashihara.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 8 Pages: 1253-1258
- DOI
  10.1248/bpb.b20-00337
- NAID
  130007883792
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-08-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20K17388
[Journal Article] Cytotoxic activities of sesquiterpenoids from the aerial parts of Petasites japonicus against cancer stem cells.2020
- Author(s)
  Takahiro Matsumoto, Daisuke Imahori, Youhei Saito, Wei Zhang, Tomoe Ohta, Tatsusada Yoshida, Yuji Nakayama, Eishi Ashihara, Tetsushi Watanabe
- Journal Title
  
  J. Nat. Med.
  
  Volume: 74 Issue: 4 Pages: 689-701
- DOI
  10.1007/s11418-020-01420-x
- NAID
  40022344636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20H03397, KAKENHI-PROJECT-20J14567
[Journal Article] Peripheral blood-derived microglia-like cells decrease amyloid-β burden and ameliorate cognitive impairment in a mouse model of Alzheimer’s disease.2020
- Author(s)
  Kuroda E., Takata K., Nishimura K., Oka H., Sueyoshi M., Aitani M., Kouda A., Satake S., Shima C., Toda Y., Nakata S., Kitamura Y., and Ashihara E.
- Journal Title
  
  J. Alzheimers Dis.
  
  Volume: 73 (1) Issue: 1 Pages: 413-429
- DOI
  10.3233/jad-190974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06904, KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-19J15414
[Journal Article] Development of Antibody-Oligonucleotide Complexes for targeting Exosomal microRNA.2020
- Author(s)
  Asako Yamayoshi, Shota Oyama, Yusuke Kishimoto, Ryo Konishi, Tsuyoshi Yamamoto, Akio Kobori, Hiroshi Harada, Eishi Ashihara, Hiroshi Sugiyama, Akira Murakami.
- Journal Title
  
  Pharmaceutic
  
  Volume: 12 Issue: 6 Pages: 545-545
- DOI
  10.3390/pharmaceutics12060545
- NAID
  120006988115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PUBLICLY-20H05033, KAKENHI-PLANNED-20H05874, KAKENHI-PROJECT-18H02087, KAKENHI-PROJECT-20H03621, KAKENHI-PROJECT-19K22595, KAKENHI-PROJECT-18KK0241
[Journal Article] Preclinical orthotopic xenograft model of renal pelvis cancer in which cancer growth could be traced by an in vivo imaging system.2019
- Author(s)
  Shimizu T, Miyashita M, Fujihara A, Hongo F, Ukimura O, Ashihara E.
- Journal Title
  
  Int J Urol.
  
  Volume: 26 Issue: 1 Pages: 138-139
- DOI
  10.1111/iju.13829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826
[Journal Article] 6-Hydroxythiobinupharidine Inhibits Migration of LM8 Osteosarcoma Cells by Decreasing Expression of LIM Domain Kinase 1.2019
- Author(s)
  Yoshizawa M, Nakamura S, Sugiyama Y, Tamai S, Ishida Y, Sueyoshi M, Toda Y, Hosogi S, Yano Y, Ashihara E.
- Journal Title
  
  Anticancer Res.
  
  Volume: 39 Issue: 12 Pages: 6507-6513
- DOI
  10.21873/anticanres.13865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826
[Journal Article] DJ-1 Contributes to Self-renewal of Stem Cells in the U87-MG Glioblastoma Cell Line.2019
- Author(s)
  Toda Y, Yoshimura R, Itahara M, Imai Y, Yamada K, Uno T, Nakata S, Hosogi S, Takata K, Ashihara E.
- Journal Title
  
  Anticancer Res.
  
  Volume: 39 Issue: 11 Pages: 5983-5990
- DOI
  10.21873/anticanres.13803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826
[Journal Article] Cytotoxic effects of zoledronic acid-loaded hydroxyapatite and bone cement in malignant tumors2017
- Author(s)
  Koto Kazutaka、Murata Hiroaki、Sawai Yasushi、Ashihara Eishi、Horii Motoyuki、Kubo Toshikazu
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Issue: 2 Pages: 1648-1656
- DOI
  10.3892/ol.2017.6355
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462274
[Journal Article] CG13250, a novel bromodomain inhibitor, suppresses proliferation of multiple myeloma cells in an orthotopic mouse model.2017
- Author(s)
  Natsuki Imaysohi, Makoto Yoshioka, Jay Chauhan, Susumu Nakata, Yuki Toda, Steven Fletcher, Jeffrey Strovel, Kazuyuki Takata, and Eishi Ashihara.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 484 Issue: 2 Pages: 262-268
- DOI
  10.1016/j.bbrc.2017.01.088
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461436, KAKENHI-PROJECT-16K08722
[Journal Article] Myeloid-derived Suppressor Cells Recruit CD4+/Foxp3+ Regulatory T Cells in a Murine Cardiac Allograft.2016
- Author(s)
  Tsukasa Nakamura, Toshimasa Nakao, Eishi Ashihara, and Norio Yoshimura.
- Journal Title
  
  Transplant Proc.
  
  Volume: 48 Issue: 4 Pages: 1275-1278
- DOI
  10.1016/j.transproceed.2015.10.060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461436
[Journal Article] Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation.2016
- Author(s)
  Kengo Matsumura, Susumu Nakata, keiko Taniguchi, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, and Tatsuhiro Yoshiki.
- Journal Title
  
  BMC Cancer
  
  Volume: 48 Issue: 1 Pages: 748-748
- DOI
  10.1186/s12885-016-2779-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461436, KAKENHI-PROJECT-15K10585, KAKENHI-PROJECT-16K08722
[Journal Article] Inhibition of monocarboxylate transporter 1 suppresses the proliferation of glioblastoma stem cells.2016
- Author(s)
  Takada T, Takata K, Ashihara E.
- Journal Title
  
  J Physiol Sci
  
  Volume: 66 Pages: 74-81
- DOI
  10.1016/j.neuint.2016.02.008
- NAID
  40020922534
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461436, KAKENHI-PROJECT-26860058, KAKENHI-PROJECT-25460109, KAKENHI-PROJECT-16H05279, KAKENHI-PROJECT-15K16321
[Journal Article] α4 Nicotinic acetylcholine receptor modulated by galantamine on nigrostriatal terminals regulates dopamine receptor-mediated rotational behavior.2016
- Author(s)
  Inden M, Takata K, Yanagisawa D, Ashihara E, Tooyama I, Chimohama S, Kitamura Y.
- Journal Title
  
  Neurochem Int
  
  Volume: 94 Pages: 74-81
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461436
[Journal Article] Daphnetin inhibits invasion and migration of LM8 murine osteosarcoma cells by decreasing RhoA and Cdc42 expression2016
- Author(s)
  Hiroki Fukuda, Seikou Nakamura, Yugo Chisaki, Tetsuya Takada, Yuki Toda, Hiroaki Murata, Kazuyuki Itoh, Yoshitaka Yano, Kazuyuki Takata, Eishi Ashihara
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 471 Issue: 1 Pages: 63-67
- DOI
  10.1016/j.bbrc.2016.01.179
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462274, KAKENHI-PROJECT-15K15560, KAKENHI-PROJECT-14J02568, KAKENHI-PROJECT-26461436
[Journal Article] Targeting the canonical Wnt /β-catenin pathway in　 hematological malignancies.2015
- Author(s)
  Ashihara E, Takada T, Maekawa T
- Journal Title
  
  Cancer Sci
  
  Volume: - Issue: 6 Pages: 665-671
- DOI
  10.1111/cas.12655
- NAID
  120005767015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390244, KAKENHI-PUBLICLY-25112706, KAKENHI-PROJECT-26461436
[Journal Article] Isopentenyl pyrophosphate secreted from zoledronate-stimulated myeloma cells, activates the chemotaxis of γδT cells.2015
- Author(s)
  Eishi Ashihara, Tatsuya Munaka, Shinya Kimura, Saori Nakagawa, Yoko Nakagawa, Masaki Kanai, Hideyo Hirai, Hirohisa Abe, Takashi Miida, Susumu Yamato, Shuichi Shoji, Taira Maekawa
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 463 Issue: 4 Pages: 650-655
- DOI
  10.1016/j.bbrc.2015.05.118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08624, KAKENHI-PROJECT-15K10604, KAKENHI-PROJECT-26461436, KAKENHI-PROJECT-25461415
[Journal Article] Monocarboxylate transporter 4, associated with the acidification of synovial fluid, is a novel therapeutic target for inflammatory arthritis.2015
- Author(s)
  Fujii W, Kawahito Y, Nagahara H, Kukida Y, Seno T, Yamamoto A, Kohno M, Oda R, Taniguchi D, Fujiwara H, EjimaA, Kishida T, Osam Mazda, Ashihara E.
- Journal Title
  
  Arthritis Rheum
  
  Volume: 67 Issue: 11 Pages: 2888-2896
- DOI
  10.1002/art.39270
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461436
[Journal Article] Rapamycin prolongs cardiac allograft survival in a mouse model by inducing myeloid-derived suppressor cells.2015
- Author(s)
  Nakamura T, Nakao T, Yoshimura N, Ashihara E.
- Journal Title
  
  Am J Transplant
  
  Volume: 15 Issue: 9 Pages: 2364-2377
- DOI
  10.1111/ajt.13276
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461436
[Journal Article] Effective internalization of U251-MG-sexcreted exosomes into cancer cells and characterization of their lipid components.2015
- Author(s)
  Toda Y, Takata K, Nakagawa Y, Kawakami H, Fujioka S, Kobayashi K, Hattori Y, Kitamura Y, Akaji K, Ashihara E.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 456 Pages: 768-773
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461436
[Journal Article] Myeloid-derived suppressor cells in autoimmune diseases2014
- Author(s)
  Fujii W, Ashihara E, Kawahito Y
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 34（3） Pages: 124-128
- NAID
  130004943856
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461480
[Journal Article] CCR1-mediated Accumulation of Myeloid Cells in the Liver Microenvironment Promoting Mouse Colon Cancer Metastasis2014
- Author(s)
  Hirai H, et al
- Journal Title
  
  Clinical and Experimental Metastasis
  
  Volume: 32 Issue: 8 Pages: 2245-55
- DOI
  10.1002/stem.1701
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592678, KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24659461, KAKENHI-PUBLICLY-25112706, KAKENHI-PROJECT-25430149, KAKENHI-PROJECT-25461415, KAKENHI-PROJECT-26293277, KAKENHI-PROJECT-26461436
[Journal Article] Pharmacological assessment of methamphetamine-induced behavioral hyperactivity mediated by dopaminergic transmission in planarian Dugesia japonica2014
- Author(s)
  N. Tashiro, K. Nishimura, K. Daido, T. Oka, M. Todo, A. Toshikawa, J. Tsushima, K. Takata, E. Ashihara, K. Yoshimoto, K. Agata and Y. Kitamura
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 449 Issue: 4 Pages: 412-8
- DOI
  10.1016/j.bbrc.2014.05.059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22124001, KAKENHI-PROJECT-26461436
[Journal Article] Surface chemical approach to single-step measurement of antibody in human serum using localized surface plasmon resonance biosensor on microtiter plate system.2014
- Author(s)
  Yamamichi J, Ojima T, Iida M, Yurugi K, Imamura T, Ashihara E, Kimura S, Maekawa T.
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: 406 Issue: 18 Pages: 4527-4533
- DOI
  10.1007/s00216-014-7833-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461436
[Journal Article] Therapeutic effects of human mesenchymal and hematopoietic stem cells on rotenone-treated parkinsonian mice2013
- Author(s)
  Inden M, Takata K, Nishimura K, Kitamura Y, Ashihara E, Yoshimoto K, Ariga H, Honmou O, Shimohama S
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 91 Issue: 1 Pages: 62-72
- DOI
  10.1002/jnr.23128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390180, KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23659460, KAKENHI-PROJECT-24590222, KAKENHI-PROJECT-25460109
[Journal Article] C/EBPβ promotes BCR-ABL-mediated myeloid expansion and leukemic stem cell exhaustion.2013
- Author(s)
  5. Hayashi Y, Hirai H, Kamio N, Yao H, Yoshioka S, Miura Y, Ashihara E, Fujiyama Y, Tenen DG, Maekawa T.
- Journal Title
  
  Leukemia
  
  Volume: 27 Issue: 3 Pages: 619-628
- DOI
  10.1038/leu.2012.258
- NAID
  120005466670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23592678, KAKENHI-PROJECT-23890090, KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24659461, KAKENHI-PUBLICLY-25112706, KAKENHI-PROJECT-25430149, KAKENHI-PROJECT-25461415, KAKENHI-PUBLICLY-23112507
[Journal Article] Myeloid-Derived Suppressor Cells Play Crucial Roles in the Regulation of Mouse Collagen-Induced Arthritis.2013
- Author(s)
  1. Fujii W, Ashihara E, Hirai H, Nagahara H, Kajitani N, Fujioka K, Murakami K, Seno T, Yamamoto A, Ishino H, Kohno M, Maekawa T, Kawahito Y.
- Journal Title
  
  J Immunol
  
  Volume: 191 Issue: 3 Pages: 1073-1081
- DOI
  10.4049/jimmunol.1203535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24659461, KAKENHI-PUBLICLY-25112706, KAKENHI-PROJECT-25430149, KAKENHI-PROJECT-25461415, KAKENHI-PROJECT-25461480
[Journal Article] Effectiveness of sulforaphane as a radiosensitizer for murine osteosarcoma cells2013
- Author(s)
  Y. Sawai, H. Murata, M. Horii, K. Koto,T. Matsui, N. Horie, Y. Tsuji, E. Ashihara, T. Maekawa, T. Kubo, S. Fushiki
- Journal Title
  
  Oncol Rep
  
  Volume: 29 Issue: 3 Pages: 941-945
- DOI
  10.3892/or.2012.2195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591668, KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24659461, KAKENHI-PUBLICLY-25112706, KAKENHI-PUBLICLY-23112507
[Journal Article] Cyclic AMP responsive element binding proteins are involved in 'emergency' granulopoiesis through the upregulation of CCAAT/enhancer binding protein β.2013
- Author(s)
  Hirai H
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 1 Pages: e54862-e54862
- DOI
  10.1371/journal.pone.0054862
- NAID
  120005242481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23592678, KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24659461, KAKENHI-PUBLICLY-23112507
[Journal Article] Quantitative comparison of protein dynamics in live cells and in vitro by in-cell (19)F-NMR.2013
- Author(s)
  Takaoka Y, Kioi Y, Morito A, Otani J, Arita K, Ashihara E, Ariyoshi M, Tochio H, Shirakawa M, Hamachi I.
- Journal Title
  
  Chem Commun
  
  Volume: 49 Issue: 27 Pages: 2801-2803
- DOI
  10.1039/c3cc39205h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21121006, KAKENHI-PLANNED-23115004, KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23750188, KAKENHI-PUBLICLY-24113711, KAKENHI-PLANNED-21121005, KAKENHI-PUBLICLY-24102516
[Journal Article] 非小細胞性肺がん患者に対する簡易懸濁法を用いたエルロチニブ投与に関する検討．2013
- Author(s)
  高田哲也、池見泰明、福土将秀、杉本充弘、石橋直哉、小林政彦、矢野育子、金永学、三嶋理晃、芦原英司、松原和夫.
- Journal Title
  
  医療薬学
  
  Volume: 39 Pages: 565-570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] Zoledronic acid significantly enhances radiation induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling.2013
- Author(s)
  8. Koto K, Murata H, Kimura S, Sawai Y, Horie N, Matsui T, Ryu K, Ashihara E, Maekawa T, Kubo T, Fushiki S.
- Journal Title
  
  Int J Oncol
  
  Volume: 42 Issue: 2 Pages: 525-534
- DOI
  10.3892/ijo.2012.1735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23592196, KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24659461, KAKENHI-PUBLICLY-25112706, KAKENHI-PUBLICLY-23112507
[Journal Article] C/EBP is involved in the amplification of early granulocyte precursors during candidemia-induced ‘emergency’ granulopoiesis.2012
- Author(s)
  Satake S
- Journal Title
  
  J Immunol
  
  Volume: 198 Issue: 9 Pages: 4546-4555
- DOI
  10.4049/jimmunol.1103007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23592678, KAKENHI-PROJECT-23890090, KAKENHI-PROJECT-24659461, KAKENHI-PUBLICLY-23112507
[Journal Article] Trarlslationalresearch of photodynamic therapy with acridine orange which targets cancer acidity.2012
- Author(s)
  Kusuzaki K, Ashihara E, Hosogi S, Matsubara T, Satonaka H, Nanamura T, Matsumine A, Murata H, Sudo A, Uchida A, Murata H, Baldini N, Fais S, Marunaka Y.
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: 18 Pages: 1414-11420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659730
[Journal Article] .Translationalresearch of photodynamic therapy with acridine orange which targets cancer acidity.2012
- Author(s)
  Kusuzaki K, Ashihara E, Hosogi S, Matsubara T, Satonaka H, Manamura T, Matsumine A, Murata H, Sudo A, Uchida A, Murata H, Baldini N, Fais S, Marunaka Y.
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: 18 Pages: 1414-11420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659730
[Journal Article] An inhibitor of Na/H(+) exchanger, ethy1-isopropyl amiloride (EIPA), diminishes proliferation of MKN28 human gastric cancer cells by decreasirlg the cytosolic Cl(-) concentration via DIDS-sensitive pathways。2012
- Author(s)
  Hosogi S, Miyazaki H, Nakajima KI, Ashihara E, Niisato N, Kusuzaki K, Marunaka Y.
- Journal Title
  
  Cell Physiol Biochem.
  
  Volume: 30 Pages: 1241-1253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659730
[Journal Article] An inhibitor of Na+/H+ exchanger (NHE), ethyl-isopropyl amiloride (EIPA), diminished proliferation of MNK28 human gastric cancer cells by decreasing the cytosolic Cl- concentration via DIDS-sensitive pathways.2012
- Author(s)
  Hosogi S
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 30 Issue: 5 Pages: 1241-1253
- DOI
  10.1159/000343315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-24590283
[Journal Article] Effects of low-intensity pulsed ultrasound (LIPUS) on osteosarcoma and cancer cells.2012
- Author(s)
  Sawai Y
- Journal Title
  
  Oncol Rep
  
  Volume: 28 Issue: 2 Pages: 481-486
- DOI
  10.3892/or.2012.1816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24659461, KAKENHI-PUBLICLY-23112507
[Journal Article] Regulation of epithelial sodium transport via epithelial Na^+channel(ENaC)2011
- Author(s)
  MARUNAKA Y, Niisato N, Taruno A, Ohta M, Miyazaki H, Hosogi S, Nakajima K, Kusuzaki K, Ashihara E, Nishio K, Iwasaki Y, Nakahari T, Kubota T
- Journal Title
  
  J Biomed Biotechnol
  
  Volume: 2011 Pages: 978196-978196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390060
[Journal Article] Galectin-3 induced by leukemia microenvironment promotes drug resistance and bone marrow lodgment in chronic myelogenous leukemia.2011
- Author(s)
  Yamamoto-Sugitani M, Kuroda J, Ashihara E,et al.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 108 Pages: 17468-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] Combined effects of novel heat shock protein 90 inhibitor NVP-AUY922 and nilotinib in a random mutagenesis screen2011
- Author(s)
  Tauchi T, Okabe S, Ashihara E. (他3名)
- Journal Title
  
  Oncogene
  
  Volume: 30 Issue: 24 Pages: 2789-2797
- DOI
  10.1038/onc.2011.3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] Rapid automated detection of ABL kinase domain mutations in imatinib-resistant patients.2011
- Author(s)
  Tanaka R, Ashihara E, Maekawa T, et al.
- Journal Title
  
  Cancer Lett
  
  Volume: 312 Pages: 228-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] Galection-9 ameliorates acute Graft-versus-host disease through the induction of T-cell apoptosis2011
- Author(s)
  Sakai K, Ashihara E, Maekawa T, et al
- Journal Title
  
  Eur J Immunol
  
  Volume: 41 Issue: 1 Pages: 67-75
- DOI
  10.1002/eji.200939931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390293, KAKENHI-PROJECT-21590443, KAKENHI-PROJECT-21591246, KAKENHI-PUBLICLY-23112507, KAKENHI-PROJECT-23256004, KAKENHI-PROJECT-23591404
[Journal Article] Combined effects of novel heat shock protein 90 inhibitor NVP-AUY922 and nilotinib in a random mutagenesis screen2011
- Author(s)
  Tauchi, T., Okabe, S., Ashihara, E., Kimura, S., Maekawa, T.
- Journal Title
  
  Oncogene
  
  Volume: 30(24) Pages: 2789-2797
- Data Source
  KAKENHI-PROJECT-21390293
[Journal Article] Rakicidin A effectively induces apoptosis in hypoxia adapted Bcr-Abl positive leukemic cells2011
- Author(s)
  Takeuchi M, Ashihara E, Maekawa T, et al
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 3 Pages: 591-6
- DOI
  10.1111/j.1349-7006.2010.01813.x
- NAID
  10029291246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390293, KAKENHI-PROJECT-21591246, KAKENHI-PUBLICLY-23112507, KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23592678
[Journal Article] RNA interference against Polo-like kinase-1 in advanced non-small cell lung cancers2011
- Author(s)
  Kawata E, Ashihara E, Maekawa T
- Journal Title
  
  J Clin Bioinformatics
  
  Volume: 1 Issue: 1 Pages: 6-6
- DOI
  10.1186/2043-9113-1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390293, KAKENHI-PUBLICLY-23112507
[Journal Article] Targeting the Wnt/β-catenin signaling pathway in human cancers2011
- Author(s)
  Yao H, Ashihara E, Maekawa T
- Journal Title
  
  Expert Opinion on Therapeutic Targets
  
  Volume: 15 Issue: 7 Pages: 873-887
- DOI
  10.1517/14728222.2011.577418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390293, KAKENHI-PUBLICLY-23112507, KAKENHI-PROJECT-23591404
[Journal Article] Rapid automated detection of ABL kinase domain mutations in imatinib-resistant patients2011
- Author(s)
  Tanaka, R., Kimura, S., Ashihara, E., Yoshimura, M., Takahashi, N., Wakita, H., Itoh, K., Nishiwaki, K., Suzuki, K., Nagao, R., Yao, H., Hayashi, Y., Satake, S., Hirai, H., Sawada, K-I., Ottmann, O. G., Melo, J. V.
- Journal Title
  
  Cancer Letter
  
  Volume: 312(2) Issue: 2 Pages: 228-34
- DOI
  10.1016/j.canlet.2011.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390293, KAKENHI-PROJECT-21591246, KAKENHI-PUBLICLY-23112507, KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23592678
[Journal Article] アンチセンス研究入門46　RNA干渉のがん治療への応用．2011
- Author(s)
  芦原英司
- Journal Title
  
  Antisense
  
  Volume: 15 Pages: 31-47
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] Rakicidin A effectively induces apoptosis in hypoxia adapted Bcr-Abl positive leukemic cells2011
- Author(s)
  Takeuchi, M., Ashihara, E., Yamazaki, Y., Kimura, S., Nakagawa, Y., Tanaka, R., Yao, H., Nagao, R., Hayashi, Y., Hirai, H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102(3) Pages: 591-596
- NAID
  10029291246
- Data Source
  KAKENHI-PROJECT-21390293
[Journal Article] Targeting the Wnt/υ-catenin signaling pathway in human cancers. Expert Opin Ther Targets2011
- Author(s)
  Yao, H., Ashihara, E.
- Journal Title
  
  Expert Opin Ther Targets
  
  Volume: 15(7) Pages: 873-887
- Data Source
  KAKENHI-PROJECT-21390293
[Journal Article] AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model2011
- Author(s)
  Yao H, Ashihara E, Maekawa T, et al
- Journal Title
  
  Blood Cancer Journal
  
  Volume: 1 Issue: 11 Pages: e43-e43
- DOI
  10.1038/bcj.2011.41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390293, KAKENHI-PUBLICLY-23112507
[Journal Article] Targeting the Wnt/beta-catenin signaling pathway in human cancers.2011
- Author(s)
  Yao H, Ashihara E, Maekawa T.
- Journal Title
  
  Expert Opinion on Therapeutic Targets
  
  Volume: 15 Pages: 873-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] Regulation of epithelial sodium transport via epithelial Na^+ channel (ENaC)2011
- Author(s)
  Marunaka Y, Niisato N, Taruno A, Ohta M, Miyazaki H, Hosogi S, Nakajima K, Kusuzaki K, Ashihara E, Nishio K, Iwasaki Y, Nakahari T, Kubota T
- Journal Title
  
  J Biomed Biotechnol
  
  Volume: 2011 Issue: 1 Pages: 978196-978196
- DOI
  10.1155/2011/978196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390060, KAKENHI-PROJECT-21590243, KAKENHI-PROJECT-22790215
[Journal Article] Galectin-3 induced by leukemia microenvironment promotes drug resistance and bone marrow lodgment in chronic myelogenous leukemia2011
- Author(s)
  Yamamoto-Sugitani, M., Kuroda, J., Ashihara, E., Nagoshi, H., Kobayashi, T., Matsumoto, Y., Sasaki, N., Kiyota, M., Nakayama, R., Akaji, K., Taki, T., Uoshima, N., Kobayashi, Y., Horiike, S., Maekawa, T.
- Journal Title
  
  Proc. Natl. Acad. Sci.
  
  Volume: 108(42) Pages: 17468-17473
- Data Source
  KAKENHI-PROJECT-21390293
[Journal Article] Growth inhibition of imatinib-resistant CML cells with the T315 mutation and hypoxia-adaptation by AV65 。Va novel Wnt/υ-catenin signaling inhibitor2011
- Author(s)
  Nagao, R., Ashihara, E., Kimura, S., Strovel, J. W., Yao, H., Takeuchi, M., Tanaka, R., Hayashi, Y., Hirai, H., Padia, J., Strand, K.
- Journal Title
  
  Cancer Letter
  
  Volume: 312(1) Issue: 1 Pages: 91-100
- DOI
  10.1016/j.canlet.2011.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390293, KAKENHI-PROJECT-21590443, KAKENHI-PROJECT-21591246, KAKENHI-PUBLICLY-23112507, KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23592678
[Journal Article] Galectin-3(Gal-3) induced by leukemia microenvironment promotes drug resistance and bone marrow lodgment in chronic myelogenous leukemia2011
- Author(s)
  Yamamoto-Sugitani M, Kuroda J, Ashihara E, Nagoshi H, Kobayashi T, Matsumoto Y, Sasaki N, Shimura Y, Kiyota M, Nakayama R, Akaji K, Taki T, Uoshima N, Kobayashi Y, Horiike S, Maekawa T, Taniwaki M
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108 Issue: 42 Pages: 17468-17473
- DOI
  10.1073/pnas.1111138108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390098, KAKENHI-PROJECT-21390293, KAKENHI-PROJECT-22591172, KAKENHI-PUBLICLY-23112507, KAKENHI-PROJECT-23591404
[Journal Article] Growth inhibition of imatinib-resistant CML cells with the T315I mutation and hypoxia-adaptation by AV65, a novel Wnt/beta-catenin signaling inhibitor.2011
- Author(s)
  Nagao R, Ashihara E, Maekawa T, et al.
- Journal Title
  
  Cancer Lett
  
  Volume: 312 Pages: 91-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] AV-65, a novel Wnt/βcatenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model2011
- Author(s)
  Yao H, Ashihara E, Yokota A, Shimazaki C. (他13名)
- Journal Title
  
  Blood Cancer J
  
  Volume: 1 Issue: 6 Pages: 903-909
- DOI
  10.1038/bjc.2011.41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] A novel Wnt/β-catenin signal inhibitor successfully suppresses progression of multiple myeloma in a mouse model2011
- Author(s)
  Yao, H., Ashihara, E., Strovel, J. W., Nakagawa, Y., Kuroda, J., Nagao, R., Tanaka, R., Yokota, A., Takeuchi, M., Sakai, K., Shimazaki, C., Taniwaki, M., Strand, K., Padia, J., Hirai, H., Kimura, S.
- Journal Title
  
  Blood Cancer J
  
  Volume: 1
- Data Source
  KAKENHI-PROJECT-21390293
[Journal Article] RNA Interference against Polo-like kinase-1 in advanced non-small cell lung cancers.2011
- Author(s)
  Kawata E, Ashihara E, Maekawa T.
- Journal Title
  
  J Clin Bioinformatics
  
  Volume: 1 Pages: 6-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] Rakicidin A effectively induces apoptosis in hypoxia adapted Bcr-Abl positive leukemic cells.2011
- Author(s)
  Takeuchi M, Ashihara E, Maekawa T,et al.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 591-6
- NAID
  10029291246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] Galection-9 ameliorates acute Graft-versus-host disease through the induction of T-cell apoptosis..2011
- Author(s)
  Sakai K, Ashihara E, Maekawa T,et al.
- Journal Title
  
  Eur J Immunol
  
  Volume: 39 Pages: 67-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Journal Article] RNA干渉を用いたがん治療2010
- Author(s)
  芦原英司
- Journal Title
  
  癌と化学療法
  
  Volume: 37 Pages: 2033-2041
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] Future prospect of RNA interference for cancer therapies. Curr Drug Targets.2010
- Author(s)
  Ashihara, E., Kawata, E.
- Journal Title
  
  Curr Drug Targets.
  
  Volume: 11(3) Pages: 345-360
- Data Source
  KAKENHI-PROJECT-21390293
[Journal Article] Anti-myeloma activity of modified galectin-9 through JNK and p38 MAPK pathways.2010
- Author(s)
  Kobayashi T, Kuroda J, Ashihara E, Terui Y, Oomizu S, Yamamoto M, Taniyama A, Matsumoto Y, Horiike S, Hatake K, Yamauchi A, Hirashima M, Taniwaki F.
- Journal Title
  
  Leukemia 24
  
  Pages: 843-850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] RNA干渉による造血器悪性腫瘍治療2010
- Author(s)
  芦原英司
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 119 Pages: 729-746
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] Activity of the multi-targeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL positive leukemic cells2010
- Author(s)
  Tanaka, R., Squires, M. S., Kimura, S., Yokota, A., Mallet, K., Smyth, T., Thompson, N. T., Nagao, R., Yamauchi, T., Ashihara, E., Ottmann, O. G., Lyons, J. F.
- Journal Title
  
  Blood
  
  Volume: 116(12) Pages: 2089-2095
- Data Source
  KAKENHI-PROJECT-21390293
[Journal Article] RNA干渉を用いたがん治療2010
- Author(s)
  芦原英司
- Journal Title
  
  癌と化学療法 37
  
  Pages: 2033-2041
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] Future Prospect of RNA interference for cancer therapies.2010
- Author(s)
  Ashihara E
- Journal Title
  
  Curr Drug Targets 11
  
  Pages: 345-360
- NAID
  10025634713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] Future Prospect of RNA interference for cancer therapies.2010
- Author(s)
  Ashihara E, Kawata E, Maekawa T
- Journal Title
  
  Curr Drug Targets 11
  
  Pages: 345-360
- NAID
  10025634713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like 5characteristics in a hypoxic environment2010
- Author(s)
  Takeuchi, M., Kimura, S., Kuroda, J., Ashihara, E., Kawatani, M., Osada, H., Umezawa, K., Yasui, E., Imoto, M., Tsuruo, T., Yokota, A., Tanaka, T., Nagao, R., Nakahata, T., Fujiyama, Y.
- Journal Title
  
  Cell Death Diff
  
  Volume: 7 Pages: 1211-1220
- Data Source
  KAKENHI-PROJECT-21390293
[Journal Article] A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro.2010
- Author(s)
  Kawata E, Ashihara E, Nakagawa Y, Kiuchi T, Ogura M, Yao H, Sakai K, Tanaka R, Nagao R, Yokota A, Takeuchi M, Kimura S, Hirai H, Maekawa T.
- Journal Title
  
  Cancer Lett 294
  
  Pages: 245-253
- NAID
  120002462958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] Dual BCR-ABL/LYN tyrosine kinase inhibitor2009
- Author(s)
  Takeuchi M, Kimura S, Ashihara E, Maekawa T
- Journal Title
  
  Drug Fut
  
  Volume: 34(4) Pages: 261-269
- Data Source
  KAKENHI-PROJECT-21390293
[Journal Article] β-catenin siRNA successfully suppressed progression of multiple myeloma in a mouse model.2009
- Author(s)
  Ashihara E, Kawata E, Nakagawa Y, Shimazaki C, Kuroda J, Taniguchi T, Uchiyama H, Tanaka R, Yokota A, Takeuchi M, Kamitsuji Y, Inaba T, Taniwaki M, Kimura S, Maekawa T
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 2731-2738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] β-catenin siRNA successfully suppressed progression of multiple myeloma in a mouse model.2009
- Author(s)
  Ashihara E
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 2731-2738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] RNA干渉を用いたがん治療の可能性2009
- Author(s)
  芦原英司
- Journal Title
  
  臨床血液(教育講演特集号) 50
  
  Pages: 1577-1588
- NAID
  10025634713
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] Dua I BCR-ABL/LYN tyrosine kinase inhibitor2009
- Author(s)
  Takeuchi, M., Kimura, S., Ashihara, E., Maekawa, T
- Journal Title
  
  Drug of the Future INNO-406(in press)
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] Comaprison of imatinib, dasatinib, nilotinib, and INNO-406 in imatinib-resistant cell lines2008
- Author(s)
  Deguchi, Y., Kimura, S., Ashihara, E.,Niwa, T., Hodohara, K., Fujiyama, Y., Maekawa, T.
- Journal Title
  
  Leuk Res 32(6)
  
  Pages: 980-983
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] Anti-myeloma effect of Homoharringtonine with concomitant targeting of multiple myeloma-promoting molecules Mcl-1, XIAP and b-catenin2008
- Author(s)
  Kuroda, J., Kamitsuji, Y., Kimura, S., Ashihara, E., Nakagawa, Y., Kawata, E. Takeuchi, M., Murotani, Y., Yokota, A., Tanaka, R., Andreeff, M., Taniwaki, M., Maekawa, T.
- Journal Title
  
  Int J Hematol 87(5)
  
  Pages: 507-515
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] ABT-737 is a useful component of combinatory chemotherapies for chronic myelogenous leukaemias with diverse drug resistance mechanisms2008
- Author(s)
  Kuroda, J., Kimura, S., Kamitsuji, Y., Yokota, A., Ashihara, E., Kawata, E., Takeuchi, M., Tanaka, R., Tanaka, H., Matsumoto, Y., Andreeff, M., Taniwaki, M., Maekawa, T.
- Journal Title
  
  Brit J Haematol 140(2)
  
  Pages: 181-190
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer.2008
- Author(s)
  Kawata E, Ashihara E, Kimura S, Takenaka K, Sato K, Tanaka R, Yokota A, Kamitsuji Y, Takeuchi M, Kuroda J, Tanaka F, Yoshikawa T, Maekawa T.
- Journal Title
  
  Mol Cancer Ther 7
  
  Pages: 2904-2912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] Detection of the V617F mutation in JAK2 using a novel, fully automated2008
- Author(s)
  Tanaka, R., Kuroda, J., Stevenson, I. Ashihara, E., Ishikawa, T., Taki, T. Kobayashi, Y., Kamitsuji, Y., Kawata, E., Takeuchi, M., Murotani, Y., Yokota, A., Hirai, M., Majima, S., Taniwaki, M. Maekawa, T., Kimura, S
- Journal Title
  
  SNP super-rapid detector. Leuk Res 32(9)
  
  Pages: 1462-1467
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] Modes of cell death execution and autophagy by INNO-406, a Bcr-Abl kinase inhibitor, in Bcr-Abl-positive leukemias2008
- Author(s)
  Kamitsuji, Y., Kuroda, J., Kimura, S., Toyokuni, S., Watanabe, K., Ashihara, E., Tanaka, H., Watanabe, M., Matsubara, H., Mizushima, Y., Hiraumi, Y., Kawata E., Yoshikawa, T., Maekawa, T., Nakahata, T., Adachi, S
- Journal Title
  
  Cell Death Diff 15(11)
  
  Pages: 1712-1722
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] Anti-myeloma effect of homoharringtonine with concomitant targeting of the myeloma-promoting molecules, Mcl-1, XIAP, and beta-catenin.2008
- Author(s)
  Kuroda J, Kamitsuji Y, Kimura S, Ashihara E, Kawata E, Nakagawa Y, Takeuichi M, Murotani Y, Yokota A, Tanaka R, Andreeff M, Taniwaki M, Maekawa T.
- Journal Title
  
  Int J Hematol 87
  
  Pages: 507-515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor suppresses the growth of Ph^+ leukemia cells in the central nervous system and cyclosporine A augments its in vivo activity2007
- Author(s)
  Yokota, A., Kimura, S., Masuda, S., Ashihara, E., Kuroda, J., Sato, K., Kamitsuji, Y., Kawata, E., Deguchi, Y., Urasaki, Y., Terui, Y., Ruthardt, M., Ueda, T., Hatake, K., Inui, K., and Maekawa, T.
- Journal Title
  
  Blood 109(1)
  
  Pages: 306-314
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] Anti-donor antibody in patients receiving ABO-identical and HLA-mismatched living donor liver transplants : effect on survival2007
- Author(s)
  Ashihara E, et al.
- Journal Title
  
  Transplantation 83・4
  
  Pages: 506-509
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] The Bcr-Abl tyrosine kinase inhibitor imatinib and promising new agents against Philadelphia chromosome positive leukemias2007
- Author(s)
  Maekawa, T., Ashihara, E., Kimura, S.
- Journal Title
  
  Review. Int J Clin Oncol 12(5)
  
  Pages: 327-340
- NAID
  10019800087
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] γδ T cells kill myeloma cell by sensing mevalonate metabolites and ICAM-1 molecules on cell surface2007
- Author(s)
  Uchida, R., Ashihara, E., Sato, K., Kimura, S., et. al.
- Journal Title
  
  Biochem Biophys Res Commun 354
  
  Pages: 613-618
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Journal Article] Antidonor antibody in patients receiving ABO-identical and HLA-mismatched living donor liver transplants: effect on survival2007
- Author(s)
  Ashihara E
- Journal Title
  
  Transplantation 83
  
  Pages: 506-509
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591056
[Journal Article] Dual molecular targeting by INNO-406, a second generation Bcr-Abl inhibitor, and ABT737, an inhibitor of anti-apoptotic Bcl-2 proteins against Bcr-Abl-positive leukemia2007
- Author(s)
  Kuroda, J., Kimura, S., Strasser, A., Andreeff, M., O' Reilly, L.A., Ashihara, E., Kamitsuji, Y., Yokota, A., Kawata, E., Deguchi, Y., Takeuchi, M., Tabe, Y., Taniwaki, M., Maekawa, T.
- Journal Title
  
  Cell Death Diff 14(9)
  
  Pages: 1667-77
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] siRNAのデリバリーシステム2006
- Author(s)
  芦原英司
- Journal Title
  
  最新医学 61
  
  Pages: 1102-1109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Journal Article] New tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia(review)2006
- Author(s)
  Kimura, S., Ashihara, E., Maekawa, T.
- Journal Title
  
  Curr Pharma. Biotech 7(5)
  
  Pages: 371-379
- Data Source
  KAKENHI-PROJECT-18390283
[Journal Article] Targeting the Wnt/β-catenin signaling pathway in human cancers.
- Author(s)
  Yao H, Ashihara E, Maekawa T
- Journal Title
  
  Expert Opinion on Therapeutic Targets in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591121
[Journal Article] Parathyroid hormone enhances hematopoietic expansion via upregulation of cadherin-11 in bone marrow mesenchymal stromal cells
- Author(s)
  Yao H, Miura Y, Ashihara E, Hirai H, et al. (他11名)
- Journal Title
  
  Stem Cells
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404
[Patent] 細胞選別器及び細胞選別方法2011
- Inventor(s)
  務中達也、阿部浩久、叶井正樹、前川平、木村晋也、芦原英司
- Industrial Property Rights Holder
  株式会社島津製作所国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2011-210160
- Filing Date
  2011-09-27
- Overseas
- Data Source
  KAKENHI-PROJECT-23591404
[Patent] 細胞培養容器及びその容器を用いた細胞培養方法2010
- Inventor(s)
  務中達也(島津製作所)、阿部浩久(島津製作所)、叶井正樹(島津製作所)、明地将一(島津製作所)、前川平、木村晋也(佐賀大学)、芦原英司(京都府立医科大学)、庄子習一(早稲田大学)、川合健太郎(早稲田大学)
- Industrial Property Rights Holder
  務中達也(島津製作所)、阿部浩久(島津製作所)、叶井正樹(島津製作所)、明地将一(島津製作所)、前川平、木村晋也(佐賀大学)、芦原英司(京都府立医科大学)、庄子習一(早稲田大学)、川合健太郎(早稲田大学)
- Filing Date
  2010-09-08
- Data Source
  KAKENHI-PROJECT-21390293
[Patent] 細胞培養容器及びその容器を用いた細胞培養方法2010
- Inventor(s)
  務中達也、阿部浩久、叶井正樹、明地将一、前川平、木村晋也、芦原英司、庄子習一、川合健太郎
- Industrial Property Rights Holder
  島津製作所、京都大学、早稲田大学
- Industrial Property Number
  2010-200679
- Filing Date
  2010-09-08
- Data Source
  KAKENHI-PROJECT-20591121
[Patent] 細胞運動評価用マイクロ反応装置2009
- Inventor(s)
  務中達也、阿部浩久、叶井正樹、前川平、木村晋也、芦原英司、庄子習一
- Industrial Property Rights Holder
  島津製作所、京都大学、早稲田大学
- Industrial Property Number
  2009-148339
- Filing Date
  2009-06-23
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] pH-low insertion peptideを用いた転移予定臓器における組織酸性化の検出2022
- Author(s)
  松井透磨, 戸田侑紀, 中井亮太, 横川碧, 板垣里奈, 細木誠之, 芦原英司
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] UCHL5 overexpression confers resistance to BETi in MLL-r leukemia cells by suppressing degradation of BRD4 protein.2021
- Author(s)
  Keigo Amari, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura and Eishi Ashihara.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] A novel dipeptide type Wnt/β-catenin pathway inhibitor suppresses proliferation of acute myelogenous leukemia cells2021
- Author(s)
  Yuki Hadate, Ryosuke Wakabayashi, Yasunao Hattori, ShigekuniHosogi, Yuki Toda, Kazuyuki Takata, Eishi Ashihara
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Butyrophilin3A1のγδT細胞の増幅効率の予測マーカーとしての有用性.2021
- Author(s)
  大村真穂, 友金眞光, 戸田侑紀, 細木誠之, 芦原英司,
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] A novel coumarin-based compound inhibits invasion and migration of osteosarcoma cells2021
- Author(s)
  Yuki Sugiyama, Seikou Nakamura, Kimika Yamaguchi, Yasunao Hattori, Yuki Toda, Shigekuni Hosogi, Eishi Ashihara
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 前立腺がん幹細胞に対するγδT細胞の抗腫瘍効果.2020
- Author(s)
  宮下雅亜、友金眞光、佐野友亮、清水輝記、藤原敦子、浮村　理、芦原英司.
- Organizer
  第79回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 在宅医療における大学院がん専門薬剤師育成プログラム (在宅チーム医療研修) の構築.2020
- Author(s)
  友金眞光、中村暢彦、小原章央、村上成美、尾下玲子、今西孝至、小林篤史、宇野進、渡辺康介、楠本正明、芦原英司.
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] ovel BET/CBP/p300 multi-bromodomain inhibitors as a strategy for MLL-rearranged ALL.2020
- Author(s)
  Natsuki Imayoshi, Makoto Yoshioka, Kuniaki Tanaka, Shyh-Ming Yang, Koshi Akahane, Yuki Toda, Shigekuni Hosogi, Takeshi Inukai, Seiji Okada, David J. Maloney, Itaru Kato, Eishi Ashihara.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 低酸素環境に適応した多発性骨髄腫に対するγδT細胞の抗腫瘍効果.2020
- Author(s)
  佐野友亮、友金眞光、清水大器、宮下雅亜、戸田侑紀、細木誠之、芦原英司.
- Organizer
  第79回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 骨髄系細胞が動員された前転移ニッチにおける乳酸アシドーシス.2020
- Author(s)
  松井透磨、戸田侑紀、細木誠之、芦原英司.
- Organizer
  第79回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] γδT細胞の体外増幅培養における予測可能なバイオマーカーの探索.2020
- Author(s)
  金眞光、宮下雅亜、佐野友亮、清水大器、戸田侑紀、細木誠之、芦原英司.
- Organizer
  第79回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Anti-tumor effects of a novel Wnt/β-catenin pathway inhibitor against acute myelogenous leukemia.2020
- Author(s)
  Ryosuke Wakabayashi, Yasunao Hattori, Yusuke Sano, Yuki Sugiyama, Natsuki Imayoshi, Makou Tomogane, Keigo Amari, Yuki Toda,　Kazuya Kobayashi, Shigekuni Hosogi, Kenichi Akaji, Eishi Ashihara.
- Organizer
  The 3rd International Cancer Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 前立腺がん幹細胞に対するδT細胞の抗腫瘍効果検討.2020
- Author(s)
  宮下雅亜、友金眞光、清水輝記、藤原敦子、本郷文弥、芦原英司、浮村　理.
- Organizer
  第29回泌尿器科分子・細胞研究会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 急性骨髄性白血病に対するWnt/β-catenin経路阻害効果を有する新規抗がん剤の抗腫瘍効果.2020
- Author(s)
  若林亮介、服部恭尚、羽立祐貴、戸田侑紀、細木誠之、赤路健一、芦原英司.
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Cdk4/6 inhibitor Abemaciclib overcomes resistance to BET inhibitor in leukemic cells with MLL-AF5q31 fusion gene.2020
- Author(s)
  Keigo Amari, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura, Eishi Ashihara.
- Organizer
  American Association for Cancer Research (AACR) Annual Meeting 2020
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 急性骨髄性白血病に対する新規ペプチド型Wnt/β-catenin阻害剤の効果.2020
- Author(s)
  若林亮介、服部恭尚、戸田侑紀、細木誠之、芦原英司.
- Organizer
  第79回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Cdk4/6i Abemaciclib overcomes resistance to BETi in leukemic cells with MLL-AF5q31 fusion gene2020
- Author(s)
  Keigo Amari, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura, Eishi Ashihara..
- Organizer
  第82回日本血液学会学術集会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 骨髄系細胞が動員された前転移ニッチにおける乳酸アシドーシス.2020
- Author(s)
  松井透磨、戸田侑紀、沢田瑛子、浅山菜々子、板原多勇、中井亮太、横川碧、細木誠之、芦原英司.
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Application of BET/CBP/p300 multi-bromodomain inhibitors as a novel therapeutic strategy for MLL-rearranged acute lymphoblastic leukemia.2020
- Author(s)
  Natsuki Imayoshi, Makoto Yoshioka, Shyh-Ming Yang, Koshi Akahane, Yuki Toda, Shigekuni Hosogi, Takeshi Inukai, Seiji Okada, David J. Maloney, Jeffrey W. Strovel, Eishi Ashihara.
- Organizer
  American Association for Cancer Research (AACR) Annual Meeting 2020
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Leukemic cells with MLL-AF5q31 fusion acquire BET inhibitor resistance by upregulation Bcl-2 expression.2020
- Author(s)
  Keigo Amari, Natsuki Imayoshi, Yusuke Sano, Yuki Sugiyama, Makou Tomogane, Ryosuke Wakabayashi, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura Eishi Ashihara.
- Organizer
  The 3rd International Cancer Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Exosomal lipids applicable to cancer targeting.2019
- Author(s)
  Yuki Toda, Saeka Ukai, Akari Kobayashi, Shin-ya Morita, Eishi Ashihara
- Organizer
  The 8th Congress of the International Society for Extracellular Vesicles
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Coumarin-based compounds inhibit migration and invasion of murine osteosarcoma LM-8 cells.2019
- Author(s)
  杉山雄輝、山下正行、中村誠宏、長谷川功紀、西口大生、笠原愛実、吉澤正人、戸田侑紀、細木誠之、芦原英司
- Organizer
  第28回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Increased exosome secretion is a way of hypoxic adaptation in multiple myeloma cells.2019
- Author(s)
  Yuki Toda, Sayaka Nakayama, Shigekuni Hosogi, Eishi Ashihara
- Organizer
  The 44th Annual Meeting of the Japanese Society of Myeloma
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Development of exosome-capturing antibody-conjugated nucleic acid medicines targeting multiple myeloma cells.2019
- Author(s)
  Emi Soma, Yuki Toda, Shigekuni Hosogi, Asako Yamayoshi, Eishi Ashihara
- Organizer
  The 61st Annual Meeting of the American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Low dose gemcitabine increases the sensitivity of human Vgamma9Vdelta2T cell mediated cytotoxicity through NKG2D-NKG2D ligands axis in bladder cancer cells.2019
- Author(s)
  Teruki Shimizu, Mako Tomogane, Yusuke Sano, Daiki Shimizu, Masatsugu Miyashita, Atsuko Fujihara, Fumiya Hongo, Osamu Ukimura, Eishi Ashihara
- Organizer
  American Association for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] NOVEL DRUG DELIVERY SYSTEM FOR TARGETING EXOSOMAL MICRORNA2019
- Author(s)
  Asako Yamayoshi, Shota Oyama, Mao Tomita, Emi Soma, Eishi Ashihara, Tsuyoshi Yamamoto
- Organizer
  OTS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02087
[Presentation] Increased exosome secretion is essential for myeloma stem cells to survive in hypoxic condition.2019
- Author(s)
  Sayaka Nakayama, Yuki Toda, Shigekuni Hosogi, Eishi Ashihara
- Organizer
  The 8th Congress of the International Society for Extracellular Vesicles
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] tandard anticancer agents increase the cytotoxicity of human Vγ9Vδ2T cell via upregulation of NKG2D ligands in bladder cancer cells.2019
- Author(s)
  Teruki Shimizu, Masatsugu Miyashita, Atsuko Fujihara, Fumiya Hongo, Osamu Ukimura, Eishi Ashihara
- Organizer
  American Urological Association Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 難治性膀胱癌に対するγδT細胞と標準治療薬併用による複合免疫療法の開発2018
- Author(s)
  清水輝記、宮下雅亜、本郷文弥、浮村理、芦原英司
- Organizer
  第27回泌尿器科分子細胞研究会 (東京)
- Data Source
  KAKENHI-PROJECT-15K10604
[Presentation] Combined use of standard anticancer agents increases the cytotoxicity of human γδT cell in in vitro and in vivo in bladder cancer2018
- Author(s)
  Teruki Shimizu, Mako Tomogane, Masatsugu Miyashita, Osamu Ukimura, Eishi Ashihara
- Organizer
  第106回日本泌尿器科学会総会. (京都)
- Data Source
  KAKENHI-PROJECT-15K10604
[Presentation] NOVEL ANTIBODY-MEDIATED DRUG DELIVERY SYSTEM FOR TARGETING EXOSOMAL MICRORNA2018
- Author(s)
  Asako Yamayoshi, Ryo Konishi, Akio Kobori, Naoto Yamashita, Eishi Ashihara, Akira Murakami, Hiroshi Sugiyama 
- Organizer
  International Society for Extracellular Vesicles 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02087
[Presentation] Low dose gemcitabine increases the cytotoxicity of human γδT cell in in vitro and in an orthotopic xenograft model in bladder cancer2018
- Author(s)
  Shimizu T, Miyashita M, Tomogane M, Ukimura O, Ashihara E
- Organizer
  33rd European Association of Urology (EAU) Congress (Copenhagen)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10604
[Presentation] 難治性膀胱癌に対するγδT細胞を用いた複合免疫療法の開発、gemcitabine (GEM)併用による相乗効果の検討2017
- Author(s)
  清水輝記、友金眞光、宮下雅亜、浮村　理、芦原英司
- Organizer
  第47回京阪泌尿器腫瘍セミナー（大阪）
- Data Source
  KAKENHI-PROJECT-15K10604
[Presentation] 難治性膀胱癌に対するγδT細胞を用いた新規膀胱注入療法の開発2017
- Author(s)
  清水輝記、友金眞光、宮下雅亜、佐野友亮、清水大器、戸田侑紀、藤原敦子、高田和幸、浮村　理、芦原英司
- Organizer
  第7回4大学連携研究フォーラム（京都）
- Data Source
  KAKENHI-PROJECT-15K10604
[Presentation] Depletion of γ-glutamylcyclotransferase inhibits cancer cell growth through cellular senescence induction.2016
- Author(s)
  Kengo Matsumura, Susumu Nakata, Keiko Taniguchi, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, and Tatsuhiro Yoshiki.
- Organizer
  2016 American Society of Cell Biology ANnual Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] Chemotherapeutic agent pretreatment enhances the human T cell cytotoxicity against urinary bladder cancer cells.2016
- Author(s)
  Teruki Shimizu, Makou Tomogane, Osamu Ukimura, Eishi Ashihara.
- Organizer
  第75回日本癌学会学術総会.
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] Depletion of γ-glutamylcyclotransferase inhibits cancer cell growth via celluar senescence caused by CDK inhibitor induction.2016
- Author(s)
  Kengo Matsumura, Susumu Nakata, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, and Tatsuhiro Yoshiki.
- Organizer
  24th Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  Manchester, UK
- Year and Date
  2016-07-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] γδＴcells exert cytotoxicity against cancer cells regardless of PD-L1 expression in cancer cells.2016
- Author(s)
  Makou Tomogane, Teruki Shimizu, Yuki Toda, Kazuyuki Takata, and Eishi Ashihara.
- Organizer
  第75回日本癌学会学術総会.
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] Monitoring of lenalidomide levels for prediction of its toxicity and efficacy in myeloma patients．2016
- Author(s)
  Yoko Kado, Fumiaki Kitazawa, Masayuki Tsujimoto, Shin-ichi Fuchida, Akira Okano, Mayumi Hatsuse, Satoshi Murakami, Kumi Ueda, Takatoshi Kokufu, Ryosuke Irie, Tohko Sakashita, Mizuki Yamamoto, Tetsuya Minegaki, Kohshi Nishiguchi, Eishi Ashihara and Chihiro Shimazaki.
- Organizer
  第78回日本血液学会学術集会.
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] Depletion of γ-glutamylcyclotransferase induces cellular senescence by CDK inhibitors Induction.2016
- Author(s)
  kengo Matsumura, Susumu Nakata, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, and Tatsuhiro Yoshiki.
- Organizer
  第75回日本癌学会学術総会.
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] PRE-METASTATIC TISSUE ACIDIFICATION ) IDENTIFIED BY PH-LOW INSERTION PROBE.2016
- Author(s)
  Shusuke Fujioka, Yuki Toda, Anna Mosnikova, Oleg A. Andreev, Kazuyuki Takata, Yana K. Reshetnyak, and Eishi Ashihara
- Organizer
  第53回ペプチド討論会
- Place of Presentation
  京都
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] A novel BRD4 inhibitor CA2 suppresses MM cell proliferation in an orthotopic myeloma mouse model.2016
- Author(s)
  Natsuki Imaysohi, Makoto Yoshioka, Susumu Nakata, Jay Chauhan, Yoko Kado, Yuki Toda, Steven Fletcher, Jeffrey Strovel, Kazuyuki Takata, and Eishi Ashihara.
- Organizer
  American Society of Hematology (ASH) 58th Annual Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] 造血器悪性腫瘍に対するWnt/β-cateninシグナルを標的とした創薬研究2016
- Author(s)
  芦原英司
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] 多発性骨髄腫患者におけるレナリドミドの毒性および治療効果を予測するための至適血中濃度.2016
- Author(s)
  角　陽子、北澤文章、辻本雅之、淵田真一、岡野　晃、初瀬真弓、村頭　智、上田久美、国府孝敏、木村朱李、佐伯　崇、結城絵理子、峯垣哲也、西口工司、芦原英司、島崎千尋.
- Organizer
  第41回日本骨髄腫学会学術集会.
- Place of Presentation
  徳島
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] Prediction of the lenalidomide toxicity and its therapeutic efficacy in Japanese multiple myeloma patients by measuring its plasma concentration.2015
- Author(s)
  Kado Y, Kitazawa F, Tsujimoto M, Fuchida AI, Okano A, Hatsuse M, Murakami S, Ueda K, Kokufu T, Ozawa S, Ito K, Morishita S, Takada T, Minegishi T, Nishiguchi K, Ashihara E, Shimazaki C.
- Organizer
  The 57th Annual Meeting of American Society of Hematology.
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] Characterization of microglia-like cells derived from mouse bone marrow cells for new therapeutic strategy of Alzheimer’s disease.2015
- Author(s)
  Kawanishi S, Takata K, Takada T, Ashihara E.
- Organizer
  The 44th ISEH Annual Scientific Meeting.
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2015-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] Novel bromodomain inhibitors suppress proliferation of multiple myeloma cells.2015
- Author(s)
  Ashihara E, Oki R, Imayoshi N, Yoshioka M, Strovel JW, Honjo A, Sakai Y, Takada T, Chauhan J, Raje M, Flecher S, Takata K.
- Organizer
  The 57th Annual Meeting of American Society of Hematology.
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] Ion transport-associated molecules as therapeutic targets against glioblastoma stem cells.2015
- Author(s)
  Takada T, Takada K, Ashihara E.
- Organizer
  The 44th ISEH Annual Scientific Meeting.
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] 自己免疫性疾患における骨髄由来抑制細胞の機能解析2014
- Author(s)
  藤井　渉, 芦原英司, 川人　豊
- Organizer
  第24回日本サイトメトリー学会
- Place of Presentation
  大阪
- Year and Date
  2014-06-29
- Data Source
  KAKENHI-PROJECT-25461480
[Presentation] Cytokine-STATs signalings upregulate C/EBPβ in BCR-ABL+ leukemic cells independently from BCR-ABL/JAK-STAT pathway.2013
- Author(s)
  4. Yokota A, Hirai H, Hayashi Y, Tamura A, Sato A, Yao H, Yoshioka S, Iwasa M, Ashihara E, Miura Y, Maekawa T.
- Organizer
  The 55th Annual Meeting of American Society of Hematology.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Hypoxia-adapted myeloma cells possess stem cell-like character2013
- Author(s)
  Ashihara E, Hirai H, et al
- Organizer
  The 55^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Direct interaction with bone marrow mesenvhymal stromal/stem cells is required for hematopoietic expansion by parathyroid hormone2013
- Author(s)
  Yao H, Miura Y, Ashihara E, et al
- Organizer
  The 55^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Glioblastoma-derived exosomes targeting to cancer cells and their lipid characterization.2013
- Author(s)
  Toda Y,Takata K, Kobayashi K, Hattori Y,Akaji K, Ashihara E.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Myeloid-derived suppressor cells play crucial roles in the regulation of mouse collagen-induced arthritis.2013
- Author(s)
  Fujii W, Ashihara E, Hirai K, Fujioka K, Seno T, Ishino H, Kawahito Y.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25461480
[Presentation] Cytokine-STATs signaling upregulate C/EBPβin BCR-ABL+ leukemic cells independently from BCR-ABL/JAK-STAT pathway2013
- Author(s)
  Yokota A, Hirai H, Ashihara E, et al
- Organizer
  The 55^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Microglia-like monocytic cells derived from bone marrow cells phagocytose amyloid-β and facilitate phagocytosis of amyloid-β by resident microglia.2013
- Author(s)
  5. Takata K, Toji Y, Kawanishi S, Takada T, Kitamura Y, Ashihara E.
- Organizer
  The 55th Annual Meeting of American Society of Hematology.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Expression of C/EBPβ is involved in the exhaustion of hematopoietic stem cells through cell-intrinsic and cell-extrinsic mechanisms.2013
- Author(s)
  3. Tamura A, Hirai H, Hayashi Y, Yokota A, Sato A, Yao H, Yoshioka S, Iwasa M, Ashihara E, Miura Y, Maekawa T.
- Organizer
  The 55th Annual Meeting of American Society of Hematology.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Myeloid-derived suppressor cells have reguratory roles in mouse collagen-induced arthritis.2013
- Author(s)
  Fujii W, Ashihara E, Hirai H, Nagahara H, Fujioka K, Murakami K, Nakamura K, Seno T, Yamamoto A, Ishino H, Kohno M,Maekawa T, Kawahito Y.
- Organizer
  The annual European Congress of Rheumatology 2013
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-25461480
[Presentation] Direct interaction with bone marrow mesenchymal stromal/stem cells is required for hematopoietic expansion by parathyroid hormone.2013
- Author(s)
  2. Yao H, Miura Y, Yoshioka S, Iwasa M, Sato A, Tamura A, Yokota A, Ashihara E, Ichinohe T, Hirai H, Maekawa T.
- Organizer
  The 55th Annual Meeting of American Society of Hematology.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Myeloid-derived suppressor cells have regulatory roles in mouse collagen-induced arthritis2013
- Author(s)
  Fujii W, Ashihara E, Kawahito Y, et al
- Organizer
  The Annual European Congress of Rheumatology
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Expression of C/EBPβis involved in the exhaustion of hematopoietic stem cells through cell-intrinsic and cell-extrinsic mechanisms2013
- Author(s)
  Tamura A, Hirai H, Ashihara E, et al
- Organizer
  The 55^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Hypoxia-adapted myeloma cells possess stem cell-like character.2013
- Author(s)
  1. Ashihara E, Nakagawa Y, Yao H, Yokota A, Miura Y, Takata K, Kitamura Y, Hirai H, Maekawa T.
- Organizer
  The 55th Annual Meeting of American Society of Hematology.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Zoledronic acid significantly enhances radiation-induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling2013
- Author(s)
  Koto K, Murata H, Matsui TA, Horie N, Sawai Y, Ashihara E, Kimura S, Maekawa T, Fushiki S, Horii M, Kubo T
- Organizer
  International Society of Limb Salvage 17th General Meeting
- Place of Presentation
  Bologna, Italy
- Data Source
  KAKENHI-PROJECT-23592196
[Presentation] M-CSF刺激による造血幹細胞からのアミロイドβ貪食細胞への分化誘導.2013
- Author(s)
  高田和幸、河西翔平、杜氏裕美子、北村佳久、芦原英司
- Organizer
  第75回日本血液学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Myeloid-Derived Suppressor Cells have regulatory roles in mouse collagen-induced arthritis.2013
- Author(s)
  6. Fuji W, Ashihara E, Hirai H, Nagahara H, Fujioka K, Murakami K, Nakamura K, Seno T, Yamamoto A, Ishino H, Kohno M, Maekawa T, Kawahito Y.
- Organizer
  The Annual European Congress of Rheumatology.
- Place of Presentation
  Madrid, Spain.
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Microglia-like monocytic cells derived from bone marrow cells phagocytose amyloid-βand facilitate phagocytosis of amyloid-βby resident microglia2013
- Author(s)
  Takata K, Ashihara E, et al
- Organizer
  The 55^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] C/EBPβ-mediated expansion of hematopoietic stem/progenitors precedes'Emergency'granulopoiesis induced by cadidemia2012
- Author(s)
  Tamura A, Hirai H, Ashihara E, et al
- Organizer
  The 54^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Myeloid-derived suppressor cells accumulated in spleens of mice with collagen-induced arthritis and inhibited immune response of CD4+ T cells2012
- Author(s)
  Fujii W, Ashihara E, Kawahito Y, et al
- Organizer
  The 2012 American College of Rheumatology Annual meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] 新規Wnt/β-カテニン経路阻害剤AV65による多発性骨髄腫細胞の増殖抑制効果．2012
- Author(s)
  芦原英司
- Organizer
  ．第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] C/EBPβis upregulated through STAT5 and accelerates exhaustion of leukemic stem cells during BCR-ABL-mediated myeloid expansion2012
- Author(s)
  Hayashi H, Hirai H, Ashihara E, et al
- Organizer
  The 54^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] AV-65, a novel Wnt/β-catenin signal inhibitor, suppresses progression of multiple myeloma in a mouse model2012
- Author(s)
  Ashihara E et al
- Organizer
  The 3dr JSH International Symposium
- Place of Presentation
  Kawagoe, Japan
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] 新規Wnt/β-カテニン経路阻害剤AV65による多発性骨髄腫細胞の増殖抑制効果2012
- Author(s)
  芦原英司、他
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Combined effects of the Third-Generation Bisphosphonate and Radiation on Fibrosarcoma Cells2012
- Author(s)
  Koto K, Murata H, Sakabe T, Matsui TA, Horie N, Sawai Y, Ashihara E, Kimura S, Maekawa T, Fushiki S, Kubo T
- Organizer
  13th EFORT Congress
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-23592196
[Presentation] The mechanisms of Na^+/H^+ exchanger inhibitor on proliferation of gastric cancer cells with several pathways2012
- Author(s)
  Hosogi Shigekuni, Ohta Mariko, Nakajima Ken-ichi, Ashihara Eishi, Niisato Naomi, Marunaka Yoshinori
- Organizer
  The 89^<th> Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Matsumoto
- Data Source
  KAKENHI-PROJECT-20390060
[Presentation] AV-65, a Novel Wnt/-catenin Signal Inhibitor, Suppresses Progression of Multiple Myeloma in a Mouse Model.2012
- Author(s)
  Ashihara E.
- Organizer
  The 3rd JSH International Symposium.
- Place of Presentation
  Kawagoe, Japan
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] BCR/ABL-mediated myeloid expresion is promoted by C/EBPβ, a regulator of emergency granulopoiesis2011
- Author(s)
  Hayashi Y, Hirai H, Ashihara E, et al
- Organizer
  The 53^<rd> Annual Meeting of American Society of Hematology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Involvement of C/EBPβ in BCR/ABL-dependent leukemogenesis.2011
- Author(s)
  Hayashi Y, Hirai H, Ashihara E, et al.
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Future prospect of RNA interference for cancer therapies2011
- Author(s)
  Ashihara E
- Organizer
  The12^<th> Congress of the Asian Society of Transplantation
- Place of Presentation
  Seoul, Korea
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Combined effects of the hedgehog inhibitor LDE225 and nilotinib in a random mutagesesis screen.2011
- Author(s)
  Tauchi T, Ashihara E, Ohyasiki K, et al.
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] A microfluidic device to mimic the bone marrow environment : real-time observation of the leukemic cell behavior2011
- Author(s)
  Munaka T, Ashihara E, et al
- Organizer
  The 15^<th> International Conference on Miniaturized Systems for Chemistry and Life Sciences
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] BCR/ABL-mediated myeloid expresion is promoted by C/EBP beta, a regulator of emergency granulopoiesis.2011
- Author(s)
  Hayashi Y, Hirai H, Ashihara E, et al.
- Organizer
  第53回アメリカ血液学会
- Place of Presentation
  米国、サンディエゴ
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] クロライドイオン輸送体活性化による神経突起伸長促進機構の解明2011
- Author(s)
  丸中良典、楠崎克之、新里直美、芦原英司、中島謙一、細木誠之、羽柴光起
- Organizer
  ソルト・サイエンス研究財団第23回助成研究発表会
- Place of Presentation
  東京
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-20390060
[Presentation] A microfluidic device to mimic the bone marrow environment : real-time observation of the leukemic cell behavior2011
- Author(s)
  Munaka T, Ashihara E, Maekawa T, et al
- Organizer
  The 15^<th> International Conference on Miniaturized Systems for Chemistry and Life Sciences
- Place of Presentation
  米国、シアトル
- Data Source
  KAKENHI-PROJECT-21390293
[Presentation] AV-65 inhibited the growth of myeloma cells by enhancingβ-TrCP-mediatedβ-catenin ubiquitination2011
- Author(s)
  Yao H, Ashihara E, et al
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] An inhibitor of Na^+/H^+ exchanger (NHE), ethyl-isopropyl amiloride (EIPA), diminishes proliferation of MKN28 human gastric cancer cells by decreasing the intracellular Cl^- concentration via DIDS-sensitive pathway2011
- Author(s)
  Hosogi S, Ashihara E, Niisato N, Kusuzaki K, Marunaka Y
- Organizer
  The 2nd Symposium of the International Society for Proton Dynamics in Cancer 2011
- Place of Presentation
  Nice
- Data Source
  KAKENHI-PROJECT-20390060
[Presentation] Future prospect of RNA interference for cancer therapies.2011
- Author(s)
  Ashihara E.
- Organizer
  The12th Congress of the Asian Society of Transplantation(招待講演)
- Place of Presentation
  韓国、ソウル
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] A microfluidic device to mimic the bone marrow environment: real-time observation of the leukemic cell behavior.2011
- Author(s)
  Munaka T, Ashihara E, Maekawa T, et al.
- Organizer
  The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences.
- Place of Presentation
  米国、シアトル
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] AV-65 inhibited the growth of myeloma cells by enhancing β-TrCP-mediated β-catenin ubiquitination2011
- Author(s)
  Yao H, Ashihara E, Maekawa T, et al
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21390293
[Presentation] 胃癌細胞株MKN-28細胞株のおけるNa+/H+ exchanger (NHE)阻害剤の細胞内pH・Cl-濃度の与える影響と細胞増殖抑制機構2011
- Author(s)
  細木誠之、太田麻利子、中島謙一、宮崎裕明、芦原英司、楠崎克之、新里直美、丸中良典
- Organizer
  日本生理学会第104回近畿生理学談話会
- Place of Presentation
  大阪
- Year and Date
  2011-10-01
- Data Source
  KAKENHI-PROJECT-20390060
[Presentation] Combined effects of a pan-Abl1 kinase inhibitor, ponatinib and dasatinib against T315I mutant forms of Bcr-Abl1: in vitro and in vivo studies2011
- Author(s)
  Tauchi T, Ashihara E, Ohyashiki K, et al.
- Organizer
  第53回アメリカ血液学会
- Place of Presentation
  米国、サンディエゴ
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] BCR/ABL-mediated myeloid expansion is promoted by C/EBPβ2011
- Author(s)
  Hayashi Y, Hirai H, Yao H, Yoshioka S, Satake S, Kamio N, Miura Y, Ashihara E, Fujiyama Y, Tenen DG, Maekawa T
- Organizer
  a regulator of emergency granulopoiesis. 53rd ASH Annual Meeting and Exposition
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21390293
[Presentation] 大豆ゲニステインによる免疫細胞活性化2011
- Author(s)
  丸中良典、芦原英司、新里直美、太田麻利子
- Organizer
  第14回研究報告会(平成22年度助成課題)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20390060
[Presentation] Targeting the hedgehog signaling pathway in therapy-resistant Bcr-Abl1 positive leukemia with ponatinib2011
- Author(s)
  Tauchi T, Ashihara E, et al
- Organizer
  The 53^<rd> Annual Meeting of American Society of Hematology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Targeting the hedgehog signaling pathway in therapy-resistant Bcr-Abl1 positive leukemia with ponatinib.2011
- Author(s)
  Katagiri S, Ashihara E, Ohyashiki K, et al.
- Organizer
  第53回アメリカ血液学会
- Place of Presentation
  米国、サンディエゴ
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] AV-65 inhibited the growth of myeloma cells by enhancing β-TrCP-mediated β-catenin ubiquitination.2011
- Author(s)
  Yao H, Ashihara E, et al.
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothlioma cells in vitro.2010
- Author(s)
  Kawata T, Ashihara E, Hirai H, Maekawa T
- Organizer
  第16回日本遺伝子治療学会年次学術集会
- Place of Presentation
  栃木
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] 多発性骨髄腫に対する新規Wnt/β-cateninシグナル阻害剤の抗腫瘍効果2010
- Author(s)
  八尾尚幸、芦原英司、平位秀世、前川平
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] Isopentenyl Pyrophosphate (IPP), a Metabolite produced in Myeloma Cells Induces the Chemotaxis of yδT Cells.2010
- Author(s)
  Ashihara E
- Organizer
  The 52^<nd> American Society of Hematology Annual Meeting and Exposition.
- Place of Presentation
  米国、オーランド
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] Morphological alterations of cell membrane during apoptosis induced by photodynamic therapy with acridine orange.2010
- Author(s)
  Kusuzaki K, Hosogi S, Ashihara E, Nakajima K, Niisato N, Marunaka Y.
- Organizer
  Membrane Symposium 2010
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20390060
[Presentation] A Novel Automated Assay for the Detection of BCR-ABL Kinase Domain Mutations2010
- Author(s)
  Tanaka R, Kimura S, Hosomi T, Hirai M, Nagao R, Takeuchi M, Yao H, Sakai K, HiraiH, Ashihara E, Maekawa T
- Organizer
  15th Congress of the European Hematology Association(EHA)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-21390293
[Presentation] AV-65, a Novel inhibitor of the Wnt/β-catenin signaling pathway, inhibits the proliferation of myeloma cells.2009
- Author(s)
  Yao H, Ashihara E, Nagao R, Kimura S, Hirai H, Strovel JW, Padia J, Cholody WM, Maekawa T
- Organizer
  The 51st American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA.
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] RNA干渉によるがん治療の開発2009
- Author(s)
  芦原英司
- Organizer
  第18回日本アポトーシス研究会・学術集会
- Place of Presentation
  長崎
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] Overcoming CML with T315I Mutation～Detection and Therapeutics～. Kyoto University Global COE2009
- Author(s)
  Tanaka R, Kimura S, Nagao R, Yokota A, Takeuchi M, Yao H, Sakai K, Hirai H, Ashihara E, Maekawa T
- Organizer
  Center for Frontier Medicine International Symposium/Retreat
- Place of Presentation
  Hyogo, Japan
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-21390293
[Presentation] CREB Is Involved in the Regulation of C/EBP & beta ; During'emergency' Granulopoiesis2009
- Author(s)
  Hirai H, Kamio N, Matsusue A, Ogino S, Kimura N, Satake S, Ashihara E, Maekawa T, Tenen DG, Imanishi J
- Organizer
  The American Society of Hematology 51st Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-21390293
[Presentation] 多発性骨髄腫に対する新規Wnt/β-cateninシグナル阻害剤の抗腫瘍効果2009
- Author(s)
  八尾尚幸、芦原英司、長尾里奈、武内美紀、田中瑠璃子、横田明日美、平位秀世、前川平
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] Hypoxia-Adapted CML cells are more primitive population and are Eradication by Glyoxalase-1 Inhibitors2009
- Author(s)
  Takeuchi M, Kimura S, Kuroda J, Ashihara E, Kawatani M, Osada H, Umezawa K, Yasui E, ImotoM, Tsuruo T, Yokota A, Tanaka R, Nagao R, Nakahata T, Fujiyama Y, MaekawaT
- Organizer
  The American Society of Hematology 51st Annual Meeting and Exposition(ASH)
- Place of Presentation
  Ernest N. Morial Convention Center, New Orleans, USA
- Year and Date
  2009-12-06
- Data Source
  KAKENHI-PROJECT-21390293
[Presentation] RNA干渉を用いたがん治療の可能性.2009
- Author(s)
  芦原英司
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] Automated and Rapid Detection of BCR-ABL Kinase Domain Mutations in IM Resistant Patients with Ph+ Leukemias2009
- Author(s)
  Tanaka R, Kimura S, Hosomi T, Hirai M, Nagao R, Yokota A, Takeuchi M, Yao H, Sakai K, Adachi S, Hirai H, Ashihara E, Maekawa T
- Organizer
  The American Society of Hematology 51st Annual Meeting and Exposition(ASH)
- Place of Presentation
  Ernest N. Morial Convention Center, New Orleans, USA
- Year and Date
  2009-12-06
- Data Source
  KAKENHI-PROJECT-21390293
[Presentation] RNA干渉によるがん治療の開発2009
- Author(s)
  芦原英司
- Organizer
  第18回日本アポトーシス研究会・学術集会シンポジウム
- Place of Presentation
  長崎
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] β-catenin siRNAによる骨髄腫増殖抑制効果2008
- Author(s)
  芦原英司、河田英里、黒田純也、木村晋也、前川平
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  東京
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] 同種造血幹細胞移植後の閉塞性細気管支炎症例における末梢血血管内皮前駆細胞の動態2008
- Author(s)
  芦原英司
- Organizer
  第70回日本血液学会
- Place of Presentation
  京都
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] γδT細胞による細胞免疫療法の基礎2008
- Author(s)
  芦原英司
- Organizer
  第4回東京骨髄腫講演会
- Place of Presentation
  東京
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-20591121
[Presentation] Glyoxalase-I Is a Potential Therapeutic Target for Chronic Myelogenous Leukemia Cells That Have Acquired Drug Resistance through Adaptation to Hypoxia2007
- Author(s)
  Takeuchi M, Kuroda J, Kimura S, Ashihara E, Umezawa K, Yasui E, Kawatani M, Osada H, Hodohara K, Fujiyama Y, Maekawa T
- Organizer
  The American Society of Hematology 49th Annual Meeting and Exposition(ASH)
- Place of Presentation
  Georgia World Congress Center, Atlanta, Georgia, USA((Abstract #2931) Blood, 110:11(supple))(2007)
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-18390283
[Presentation] Kinetics of Circulating Endothelial Progenitors in Patients with Sclerodermatous Chronic Graft-Versus-Host Disease2007
- Author(s)
  Ashihara E
- Organizer
  The American Society of Hematology 49th Annual Meeting and Exposition
- Place of Presentation
  アメリカ・アトランタ
- Year and Date
  2007-12-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Presentation] β-catenin siRNAによる骨髄腫増殖抑制効果の検討.ワークショップIII「新規治療法の基礎研究」2007
- Author(s)
  芦原英司
- Organizer
  第32回日本骨髄腫研究会
- Place of Presentation
  東京
- Year and Date
  2007-11-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Presentation] 同種造血幹細胞移植後の皮膚硬化病変を有する慢性GVHD患者における末梢血血管内皮前駆細胞の動態.2007
- Author(s)
  芦原英司
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会・合同総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Presentation] ヒト非小細胞がん肝転移マウスモデルに対するアテロコラーゲンを用いたPLK-1 siRNA療法の開発(Intravenous administration of PLK-1 siRNA with atelocollagen prevents the growth of liver metastases of lung cancer.)2007
- Author(s)
  芦原英司
- Organizer
  第66回日本癌学会学術総会English Workshop
- Place of Presentation
  横浜市
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Presentation] Comparison of Imatinib, Dasatinib, Nilotinib and INNO-406 in Imatinib-Resistant Cell Lines2007
- Author(s)
  Kimura, S., Deguchi, X. Ashihara, E., Niwa, T., Hodohara, K., Fujiyama, Y., Maekawa, T
- Organizer
  The American Society of Hematology 49th Annual Meeting and Exposition
- Place of Presentation
  Atlanta, USA
- Year and Date
  2007-12-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Presentation] β-catenin siRNAによる骨髄増殖抑制効果の検討2007
- Author(s)
  芦原英司
- Organizer
  第17回アンチセンスシンポジウム
- Place of Presentation
  金沢市
- Year and Date
  2007-12-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Presentation] γδ T細胞を用いた細胞療法の開発2007
- Author(s)
  芦原英司
- Organizer
  第33回免疫カンファレンス
- Place of Presentation
  京都市
- Year and Date
  2007-11-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Presentation] 骨髄腫細胞に対するγδ T細胞の認識機構と抗腫瘍効果2006
- Author(s)
  芦原英司
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Presentation] 骨髄腫細胞に対するγδT細胞の認識機構と抗腫瘍効果2006
- Author(s)
  芦原英司
- Organizer
  第31回日本骨髄腫研究会総会
- Place of Presentation
  群馬
- Year and Date
  2006-11-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591056
[Presentation] Cyclosporin A, a P-gp inhibitor, augments the anti-central nervous system Ph+ leukemia effects of INNO-4062006
- Author(s)
  Yokota, A., Kimura, S., Masuda, S., Ashihara, E., Urasaki, Y., Terui, Y., Ruthardt, M., Ueda, T., Hatake, K., Inui, K., Maekawa, T.
- Organizer
  The American Society of Hematology 48th Annual Meeting and Exposition(ASH)
- Place of Presentation
  Orange County Convention Center, Orlando, Frorida, USA(198)((Abstract#834)Blood108:11(supple))
- Year and Date
  2006-12-12
- Data Source
  KAKENHI-PROJECT-18390283
[Presentation] Combined effects of the Third-Generation Bisphosphonate and Radiation on Fibrosarcoma Cells
- Author(s)
  Koto K, Murata H, Sakabe T, Matsui TA, Horie N, Sawai Y, Ashihara E, Kimura S, Maekawa T, Fushiki S, Kubo T.
- Organizer
  13th EFORT Congress 2012
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-23592196
[Presentation] がん細胞指向性を有するヒト星状膠芽腫細胞由来エキソソームの発見．
- Author(s)
  戸田侑紀、高田和幸、中川由布子、小林数也、服部恭尚、北村佳久、赤路健一、芦原英司．
- Organizer
  第5回日本RNAi研究会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23591404
[Presentation] Hypoxia-adapted myeloma cells possess stem cell characters.
- Author(s)
  Ashihara E, Nakagawa Y, Yao H, Takada T, Yokota A, Miura Y, Takata K, Hirai H, Kitamura Y, Maekawa T.
- Organizer
  日本癌学会シンポジウム/共同利用・共同研究拠点シンポジウム　がん幹細胞・微小環境・分子標的　～がん進展制御への挑戦
- Place of Presentation
  金沢（日本）
- Year and Date
  2015-01-21 – 2015-01-22
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] Monocarboxylate transporter (MCT) 4, associated with the decrease of synovial fluid pH, is a novel therapeutic target of rheumatoid arthritis.
- Author(s)
  Fujii W, Ashihara E, Nagahara H, Kukida Y, Kasahara A, Sagawa R, Sagawa T, Seno T, Yamamoto A, Kohno M, Oda R, Tokunaga E, Kubo, Kawahito Y.
- Organizer
  Annual European Congress of Rheumatology 2014 (The biology of rheumatoid arthritis)
- Place of Presentation
  Paris (France)
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-26461436
[Presentation] Cancer cell tropism of glioblastoma-derived exosomes regulated by their lipid components.
- Author(s)
  Toda Y, Takata K, Nakagawa Y, Kawakami H, Fujioka S, Kobayashi K, Hattori Y, Kitamura Y, Akaji K, Ashihara E.
- Organizer
  FEBS EMBO 2014 8-30 9-4
- Place of Presentation
  Paris (France)
- Year and Date
  2014-08-30 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-26461436

1. KIMURA Shinya (80359794)

# of Collaborated Projects: 7 results

# of Collaborated Products: 37 results
2. MAEKAWA Taira (80229286)

# of Collaborated Projects: 6 results

# of Collaborated Products: 45 results
3. KUSUZAKI Katsuyuki (30177993)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. SHIMAZAKI Chihiro (50170931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. HIRAI Hideyo (50315933)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
6. MURATA Hiroaki (90360031)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. KOTO Kazutaka (50649340)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. 湯浅健 (00314162)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MARUNAKA Yoshinori (00127036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
10. NIISATO Naomi (00237645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. NAKAJIMA Ken-ichi (40398392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. HOSOGI Shigekuni (30405261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
13. MIURA Yasuo (70605146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. HOSOGI Shigekuni (30433254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KAWAHITO YUTAKA (50336731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. KOHNO MASATAKA (60405256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. YAMAMOTO AIHIRO (60589878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. Nakanishi Hiyoyuki (40398376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YAMAYOSHI Asako (70380532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. 井藤千尋 (60193497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 宮崎裕明 (30360027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. 山田敏樹 (10453101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 横田明日美 (00571556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 浮村理 (70275220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
25. 中村晃和 (10381964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 上田崇 (50601598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 三木恒治 (10243239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 戸田侑紀 (40779724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 29 results
29. 河嶋秀和 (70359438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 加藤格 (10610454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 今吉菜月 (30975397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 中野正和 (70381944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 中村誠宏 (20411035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 齊藤洋平 (90411032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 小川慶子 (20844278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 松本崇宏 (30780431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 木村寛之 (50437240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 中田晋 (80590695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. TAKADA TESTUYA

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
40. SHIMIZU TERUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
41. TSUJI Yoshiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. NAKAGAWA Terumichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. ARIYOSI Mariko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 本望修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 下濱俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 北村佳久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 笹川覚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 阿形清和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 三井田孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 谷脇雅史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 白川昌宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 杤尾豪人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ashihara Eishi 芦原 英司

ASHIHARA Eishi 芦原 英司

芦原 英司 アシハラ エイシ

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Co-Researchers

Identification of novel target molecules against ALL and discovery of their seed compounds using open access dataPrincipal Investigator

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Development of exosome-capturing antibody-conjugated nucleic acid medicines against multiple myelomaPrincipal Investigator

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Development of a novel therapy against myeloma stem cells in a bone marrow hypoxic nichePrincipal Investigator

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Analysis of myeloma stem cells and their nichePrincipal Investigator

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Development of antibody-conjugatedβ-catenin siRNA therapy against multiple myelomaPrincipal Investigator

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Ashihara Eishi 芦原英司

ASHIHARA Eishi 芦原英司

芦原英司アシハラエイシ

[Book] ナーシング・グラフィカ　健康の回復と看護⑦　疾病と治療2020

[Book] Wntシグナル経路を標的とした骨髄腫治療薬開発．日本臨床　増刊号　多発性骨髄腫学―最新の診療と基礎研究―2016

[Book] 多発性骨髄腫　Updating．第4巻　移植適応骨髄腫の治療．~新規薬剤時代における移植適応患者の治療戦略~2013