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LEE Suni  李 順姫

ORCIDConnect your ORCID iD *help
Researcher Number 70414026
Other IDs
Affiliation (based on the past Project Information) *help 2011 – 2023: 川崎医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Hygiene and public health / Basic Section 58020:Hygiene and public health-related: including laboratory approach
Except Principal Investigator
Hygiene and public health / Medium-sized Section 58:Society medicine, nursing, and related fields / Hygiene / Basic Section 58020:Hygiene and public health-related: including laboratory approach
Keywords
Principal Investigator
自己免疫疾患 / 珪肺症 / 珪酸 / 環境性粒子状物質 / 免疫毒性 / 珪酸曝露 / 免疫動態 / 粉塵曝露
Except Principal Investigator
免疫 / 悪性中皮腫 … More / 産業衛生 / 石綿 / バイオマーカー / 単球 / チタン / ナノ毒性 / アポトーシス / 免疫機能 / アスベスト / NK細胞 / T細胞 / 腫瘍 / 毒性 / 天然成分 / 金属 / 細胞死 / 毒性学 / トランスクリプトーム / 中皮腫 / オートファジー / Ca2+ / カルシウムイオン / リソソーム / 予防 / リンパ球 / 空砲 / ヒト / エンドソーム / 空胞 / 制御性T細胞 / DNA損傷 / ミトコンドリア / DNAメチル化 / FoxP3 / 腫瘍免疫 / 自己免疫疾患 / 癌疾患 / 珪肺症 / 遊離ケイ酸 / 珪酸 / 強皮症 / 珪肺 / 全身性強皮症 / 自己免疫 / シリカ / T細胞機能 / NK活性 / 長期モニター / サイトカイン / 活性化 / 室内気質 / マイナス荷電粒子 Less
  • Research Projects

    (11 results)
  • Research Products

    (164 results)
  • Co-Researchers

    (13 People)
  •  Toxicity and immunological effect of metal and naturally derived biomaterial complex

    • Principal Investigator
      Nishimura Yasumitsu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Kawasaki Medical School
  •  環境物質誘発性自己免疫疾患発症のトリガーイベントの探索Principal Investigator

    • Principal Investigator
      李 順姫
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Kawasaki Medical School
  •  Exploration of immunological biomarker for diagnosis of malignant mesothelioma on the basis of transcriptome analysis

    • Principal Investigator
      Nishimura Yasumitsu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Kawasaki Medical School
  •  Exploratory research for toxic machinery of titanate nanosheet leading to immunological influences

    • Principal Investigator
      Nishimura Yasumitsu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Kawasaki Medical School
  •  Immune cell polarization in autoimmune diseases caused by environmental particlesPrincipal Investigator

    • Principal Investigator
      Lee Suni
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene and public health
    • Research Institution
      Kawasaki Medical School
  •  Comprehensive immunological-analyses for patients with malignant mesothelioma and diffuse pleural thickening

    • Principal Investigator
      NISHIMURA YASUMITSU
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene and public health
    • Research Institution
      Kawasaki Medical School
  •  Effect of short-term and long-term exposure of asbestos on regulatory T cells

    • Principal Investigator
      Matsuzaki Hidenori
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene and public health
    • Research Institution
      Prefectural University of Hiroshima
      Kawasaki Medical School
  •  Immunotoxicity of titanate nanosheets

    • Principal Investigator
      Nishimura Yasumitsu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene and public health
    • Research Institution
      Kawasaki Medical School
  •  Analysis for the effect of silica particle exposure on immune systemPrincipal Investigator

    • Principal Investigator
      Lee Suni
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene and public health
    • Research Institution
      Kawasaki Medical School
  •  Comprehensive analysis for immunological characteristics of tumor and autoimmune diseases related with mineral particles and fibers

    • Principal Investigator
      NISHIMURA Yasumitsu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kawasaki Medical School
  •  Construction of the experimental system about the immunity influence of an indoor disposition

    • Principal Investigator
      OTSUKI Takemi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kawasaki Medical School

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book Patent

  • [Book] "Asbestos fiber and immunological effects: Do immunological effects play any role in asbestos-related diseases?" in Malignant Pleural Mesothelioma; Advances in Pathogenesis, Diagnosis, and Treatments2021

    • Author(s)
      Yasumitsu Nishimura, Naoko Kumagai-Takei, Suni Lee, Kei Yoshitome, Tatsuo Ito, Takemi Otsuki
    • Total Pages
      352
    • Publisher
      Springer
    • ISBN
      9789811591587
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Book] Current Topics in Environmental Health and Preventive Medicine2020

    • Author(s)
      Lee S, Yamamoto S, Hayashi H, Matsuzaki H, Kumagai-Takei N, Hatayama T, Yu M, Ysoshitome K, Kusaka M, Nishimura Y, Otsuki T
    • Publisher
      Springer Japan
    • ISBN
    • Data Source
      KAKENHI-PROJECT-17K09171
  • [Book] "Reduction of anti-tumor immunity caused by asbestos exposure" in Allergy and Immunotoxicology in Occupational Health - The Next Step2020

    • Author(s)
      Kumagai-Takei Naoko, Lee Suni, Matsuzaki Hidenori, Maeda Megumi, Sada Nagisa, Yu Min, Yoshitome Kei, Nishimura Yasumitsu, Otsuki Takemi
    • Total Pages
      13
    • Publisher
      Springer Singapore
    • ISBN
      9789811547355
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Book] "Suppressed immune system caused by exposure to asbestos and malignant mesothelioma" in Asbestos-related Diseases2020

    • Author(s)
      Yasumitsu Nishimura, Naoko Kumagai-Takei, Suni Lee, Kei Yoshitome and Takemi Otsuki
    • Total Pages
      14
    • Publisher
      IntechOpen
    • ISBN
      9781838808334
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Book] Allergy and Immunotoxicology in Occupational Health - The Next Step2020

    • Author(s)
      Lee S, Yamamoto S, Hayashi H, Matsuzaki H, Kumagai-Takei N, Hatayama T, Yu M, Ysoshitome K, Kusaka M, Nishimura Y, Otsuki T.
    • Total Pages
      17
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-20K10437
  • [Book] "Immune Alteration Caused by Fibrous and Particulate Environmental Substances." In Environmental Factors Affecting Human Health2019

    • Author(s)
      Kumagai-Takei, N, Lee, S, Yoshitome, K, Sada, N, Nishimura, Y and Otsuki, T
    • Total Pages
      17
    • Publisher
      IntechOpen
    • ISBN
      9781789855289
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Book] Environmental Factors affecting Human Health2019

    • Author(s)
      Kumagai-Takei N, Lee S, Yoshitome K, Sada N, Nishimura Y, Otsuki T
    • Publisher
      IntechOpen
    • ISBN
      9781789855289
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Book] Cytotoxicity2018

    • Author(s)
      Yasumitsu Nishimura, Daisuke Yoshioka, Naoko Kumagai-Takei, Suni Lee, Hidenori Matsuzaki, Kei Yoshitome, Takemi Otsuki
    • Publisher
      IntechOpen
    • ISBN
      9781789234312
    • Data Source
      KAKENHI-PROJECT-18K19714
  • [Book] Cytotoxicity2018

    • Author(s)
      Yasumitsu Nishimura, Daisuke Yoshioka, Naoko Kumagai-Takei, Suni Lee, Hidenori Matsuzaki, Kei Yoshitome, Takemi Otsuki
    • Publisher
      IntechOpen
    • ISBN
      9789535158691
    • Data Source
      KAKENHI-PROJECT-15K15245
  • [Book] Lymphocyte2018

    • Author(s)
      Kumagai-Takei N, Lee S, Matsuzaki H, Sada N, Yoshitome K, Nishimura Y, Otsuki T
    • Publisher
      IntechOpen
    • ISBN
      9789535164456
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Book] Natural Killer Cells2017

    • Author(s)
      Yasumitsu Nishimura, Naoko Kumagai-Takei, Suni Lee, Hidenori Matsuzaki, Kei Yoshiotme and Takemi Otsuki
    • Total Pages
      177
    • Publisher
      IntechOpen
    • ISBN
      9789535136729
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Book] Advances in Medicine and Biology. Volume 1232017

    • Author(s)
      Kumagai-Takei N, Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Yamamoto S, Ikeda M, Hatayama T, Maeda M, Otsuki T
    • Total Pages
      257
    • Publisher
      NOVA publisher,
    • ISBN
      9781536121780
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Book] Chapter9 Immunostimulation by silica particles and the development of autoimmune dysregulation in "Immune Response Activation"2014

    • Author(s)
      Lee S, Maeda M, Hayashi H, Matsuzaki H, Kumagai-Takei N, Nishimura Y, Otsuki T
    • Total Pages
      274
    • Publisher
      InTech publisher
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Book] Immunostimulation2014

    • Author(s)
      Lee S, Maeda M, Hayashi H, Matsuzaki H, Kumagai-Takei N, Nishimura Y, Otsuki T.
    • Total Pages
      18
    • Publisher
      InTech publisher
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Book] Encyclopedia of Metalloproteins2013

    • Author(s)
      Takei-Kumagai N, Lee S, Matsuzaki H, Hayashi H, Maeda M, Nishimura Y, Otsuki T
    • Publisher
      Springer Science+Business Media
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Book] Malignant Mesothelioma2012

    • Author(s)
      Nishimura Y, Maeda M, Kumagai-Takei N, Matsuzaki H, Lee S, Fukuoka K, Nakano T, Kishimoto T, Otsuki T
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Journal Article] Increased production of matrix metalloproteinase-7 (MMP-7) by asbestos exposure enhances tissue migration of human regulatory T-like cells2021

    • Author(s)
      Lee Suni、Yamamoto Shoko、Srinivas Bandaru、Shimizu Yurika、Sada Nagisa、Yoshitome Kei、Ito Tatsuo、Kumagai-Takei Naoko、Nishimura Yasumitsu、Otsuki Takemi
    • Journal Title

      Toxicology

      Volume: 452 Pages: 152717-152717

    • DOI

      10.1016/j.tox.2021.152717

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Journal Article] Effect of IL-15 addition on asbestos-induced suppression of human cytotoxic T lymphocyte induction2021

    • Author(s)
      Kumagai-Takei Naoko、Nishimura Yasumitsu、Matsuzaki Hidenori、Lee Suni、Yoshitome Kei、Ito Tatsuo、Otsuki Takemi
    • Journal Title

      Environmental Health and Preventive Medicine

      Volume: 26 Issue: 1 Pages: 1-11

    • DOI

      10.1186/s12199-021-00967-9

    • NAID

      210000158993

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Journal Article] Ingredients such as trehalose and hesperidin taken as supplements or foods reverse alterations in human T?cells, reducing asbestos exposure-induced antitumor immunity2021

    • Author(s)
      Yamamoto Shoko、Lee Suni、Ariyasu Toshio、Endo Shin、Miyata Satomi、Yasuda Akiko、Harashima Akira、Ohta Tsunetaka、Kumagai-Τakei Naoko、Ito Tatsuo、Shimizu Yurika、Srinivas Bandaru、Sada Nagisa、Nishimura Yasumitsu、Otsuki Takemi
    • Journal Title

      International Journal of Oncology

      Volume: 58 Issue: 4 Pages: 1-9

    • DOI

      10.3892/ijo.2021.5182

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Journal Article] The Effects of Asbestos Fibers on Human T Cells2020

    • Author(s)
      Kumagai-Takei Naoko、Lee Suni、Srinivas Bandaru、Shimizu Yurika、Sada Nagisa、Yoshitome Kei、Ito Tatsuo、Nishimura Yasumitsu、Otsuki Takemi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 19 Pages: 6987-6987

    • DOI

      10.3390/ijms21196987

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Journal Article] Effect of asbestos exposure on differentiation and function of cytotoxic T lymphocytes2020

    • Author(s)
      Kumagai-Takei Naoko、Nishimura Yasumitsu、Maeda Megumi、Hayashi Hiroaki、Matsuzaki Hidenori、Lee Suni、Yoshitome Kei、Ito Tatsuo、Otsuki Takemi
    • Journal Title

      Environmental Health and Preventive Medicine

      Volume: 25 Issue: 1 Pages: 1-6

    • DOI

      10.1186/s12199-020-00900-6

    • NAID

      210000158552

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Journal Article] Enhanced expression of nicotinamide nucleotide transhydrogenase (NNT) and its role in a human T cell line continuously exposed to asbestos2020

    • Author(s)
      Yamamoto Shoko、Lee Suni、Matsuzaki Hidenori、Kumagai-Takei Naoko、Yoshitome Kei、Sada Nagisa、Shimizu Yurika、Ito Tastsuo、Nishimura Yasumitsu、Otsuki Takemi
    • Journal Title

      Environment International

      Volume: 138 Pages: 105654-105654

    • DOI

      10.1016/j.envint.2020.105654

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09157, KAKENHI-PROJECT-19H03892
  • [Journal Article] Role of Nephronectin in Pathophysiology of Silicosis2019

    • Author(s)
      Lee S, Honda M, Yamamoto S, Kumagai-Takei N, Yoshitome K, Nishimura Y, Sada N, Kon S, Otsuki T.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 10 Pages: 2581-2581

    • DOI

      10.3390/ijms20102581

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07492, KAKENHI-PROJECT-17K09171
  • [Journal Article] 結晶質シリカの生体影響について―自己寛容の破綻を中心に2019

    • Author(s)
      李順姫、武井直子、西村泰光、吉留敬、大槻剛巳
    • Journal Title

      労働衛生工学

      Volume: 58 Pages: 39-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09171
  • [Journal Article] Inflammatory alteration of human T cells exposed continuously to asbestos.2018

    • Author(s)
      Kumagai-Takei N, Yamamoto S, Lee S, Maeda M, Matsuzaki H, Sada N, Yu M, Yoshitome K, Nishimura Y, Otsuki T.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 19 Issue: 2 Pages: 504-504

    • DOI

      10.3390/ijms19020504

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09114, KAKENHI-PROJECT-16H05264
  • [Journal Article] Aberrant expression of FoxP3 in a human T?cell line possessing regulatory T cell?like function and exposed continuously to asbestos fibers2018

    • Author(s)
      Maeda Megumi、Matsuzaki Hidenori、Yamamoto Shoko、Lee Suni、Kumagai-Takei Naoko、Yoshitome Kei、Min Yu、Sada Nagisa、Nishimura Yasumitsu、Otsuki Takemi
    • Journal Title

      Oncology Reports

      Volume: 40 Pages: 748-58

    • DOI

      10.3892/or.2018.6481

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Journal Article] Skewing T helper cells exposed to asbestos fibers toward reduction of tumor immunity or activation of autoimmunity2018

    • Author(s)
      Kumagai-Takei N, Lee S, Matsuzaki H, Maeda M, Yu M, Sada N, Yoshitome K, Nishimura Y, Otsuki T
    • Journal Title

      Kawasaki Medical Journal

      Volume: 44 Pages: 33-40

    • DOI

      10.11482/KMJ-E44(1)33

    • NAID

      120006527968

    • ISSN
      0385-0234, 2434-3404
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Journal Article] 制御性T細胞の機能および細胞周期へのアスベスト曝露の影響2018

    • Author(s)
      李順姫、松﨑秀紀、武井直子、吉留敬、西村泰光、大槻剛巳
    • Journal Title

      繊維状物質研究

      Volume: 5 Pages: 130-135

    • NAID

      40021640201

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Journal Article] アスベスト曝露と中皮腫発症の免疫学的スクリーニングマーカーの探索2018

    • Author(s)
      西村泰光、武井直子、吉留敬、松﨑秀紀、李順姫、大槻剛巳
    • Journal Title

      繊維状物質研究

      Volume: 5 Pages: 102-106

    • NAID

      40021640185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Journal Article] Decrease in Intracellular Perforin Levels and IFN-γ Production in Human CD8+ T Cell Line following Long-Term Exposure to Asbestos Fibers2018

    • Author(s)
      Kumagai-Takei Naoko、Nishimura Yasumitsu、Matsuzaki Hidenori、Lee Suni、Yoshitome Kei、Otsuki Takemi
    • Journal Title

      Journal of Immunology Research

      Volume: 2018 Pages: 1-10

    • DOI

      10.1155/2018/4391731

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09114, KAKENHI-PROJECT-16H05264
  • [Journal Article] Titanate nanosheets cause caspase-dependent apoptosis of human immune cells with giant vacuole formation through endosomal defect in monocytes2017

    • Author(s)
      Nishimura Yasumitsu、Yoshioka Daisuke、Kumagai-Takei Naoko、Lee Suni、Matsuzaki Hidenori、Yoshitome Kei、Otsuki Takemi
    • Journal Title

      Toxicology Letters

      Volume: 280 Pages: S182-S183

    • DOI

      10.1016/j.toxlet.2017.07.512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15245
  • [Journal Article] Search for biomarkers of asbestos exposure and asbestos-induced cancers in investigations of the immunological effects of asbestos2017

    • Author(s)
      Matsuzaki Hidenori、Kumagai-Takei Naoko、Lee Suni、Maeda Megumi、Sada Nagisa、Hatayama Tamayo、Yamamoto Shoko、Ikeda Miho、Yoshitome Kei、Min Yu、Nishimura Yasumitsu、Otsuki Takemi
    • Journal Title

      Environmental Health and Preventive Medicine

      Volume: 22 Issue: 1

    • DOI

      10.1186/s12199-017-0661-4

    • NAID

      210000130229

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05264, KAKENHI-PROJECT-15K08788
  • [Journal Article] Accelerated cell cycle progression of human regulatory T cell-like cell line caused by continuous exposure to asbestos fibers2017

    • Author(s)
      Lee Suni、Matsuzaki Hidenori、Maeda Megumi、Yamamoto Shoko、Kumagai-Takei Naoko、Hatayama Tamayo、Ikeda Miho、Yoshitome Kei、Nishimura Yasumitsu、Otsuki Takemi
    • Journal Title

      International Journal of Oncology

      Volume: 50 Issue: 1 Pages: 66-74

    • DOI

      10.3892/ijo.2016.3776

    • NAID

      120006349212

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Journal Article] Clinical evaluation of CENP-B and Scl-70 autoantibodies in silicosis patients.2017

    • Author(s)
      Lee, S., Hayashi, H., Kumagai-Takei, N., Matsuzaki, H., Yoshitome, K., Nishimura, Y., Uragami, K., Kusaka, M., Yamamoto, S., Ikeda, M., Hatayama, T., Fujimoto, W., Otsuki, T.
    • Journal Title

      Exp. Ther. Med.

      Volume: 13 Issue: 6 Pages: 2616-2622

    • DOI

      10.3892/etm.2017.4331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Journal Article] Induction of IL-17 production from human peripheral blood CD4+ cells by asbestos exposure2017

    • Author(s)
      Maeda Megumi、Chen Ying、Lee Suni、Kumagai-Takei Naoko、Yoshitome Kei、Matsuzaki Hidenori、Yamamoto Shoko、Hatayama Tamayo、Ikeda Miho、Nishimura Yasumitsu、Otsuki Takemi
    • Journal Title

      International Journal of Oncology

      Volume: 50 Issue: 6 Pages: 2024-2032

    • DOI

      10.3892/ijo.2017.3991

    • NAID

      120006363419

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05264, KAKENHI-PROJECT-15K08788
  • [Journal Article] FoxO1 regulates apoptosis induced by asbestos in the MT-2 human T-cell line2016

    • Author(s)
      Matsuzaki, H. Lee, S. Maeda, M. Kumagai-Takei, N. Nishimura, Y. Otsuki, T.
    • Journal Title

      J Immunotoxicol

      Volume: 13 Issue: 5 Pages: 620-627

    • DOI

      10.3109/1547691x.2016.1143539

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Journal Article] The proliferative effects of asbestos-exposed peripheral blood mononuclear cells on mesothelial cells2016

    • Author(s)
      Maki Y, Nishimura Y, Toyooka S, Soh J, Tsukuda K, Shien K, Furukawa M, Muraoka T, Ueno T, Tanaka N, Yamamoto H, Asano H, Maeda M, Kumagai-Takei N, Lee S, Matsuzaki H, Otsuki T, Miyoshi S
    • Journal Title

      Oncology Letters

      Volume: 11 Issue: 5 Pages: 3308-3316

    • DOI

      10.3892/ol.2016.4412

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05264, KAKENHI-PROJECT-15K08788
  • [Journal Article] Silica and mineral silicates causing autoimmune diseases.2016

    • Author(s)
      Lee, S., Matsuzaki, H., Kumagai-Takei, N., Yamamoto, S., Hatayama, T., Yoshitome, K., Nishimura, Y., Otsuki, T.
    • Journal Title

      Kawasaki Med. J.

      Volume: 42 Pages: 15-24

    • NAID

      110010041934

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Journal Article] Environmental factors and human health: fibrous and particulate substance-induced immunological disorders and construction of a health-promoting living environment2016

    • Author(s)
      Otsuki, T. Matsuzaki, H. Lee, S. Kumagai-Takei, N. Yamamoto, S. Hatayama, T. Yoshitome, K. Nishimura, Y.
    • Journal Title

      Environ Health Prev Med

      Volume: 21 Issue: 2 Pages: 71-81

    • DOI

      10.1007/s12199-015-0499-6

    • NAID

      210000000423

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05264, KAKENHI-PROJECT-15K08788, KAKENHI-PROJECT-15K15245
  • [Journal Article] The Suppressed Induction of Human Mature Cytotoxic T Lymphocytes Caused by Asbestos Is Not due to Interleukin-2 Insufficiency2016

    • Author(s)
      Kumagai-Takei, N. Nishimura, Y. Matsuzaki, H. Lee, S. Yoshitome, K. Hayashi, H. Otsuki, T.
    • Journal Title

      J Immunol Res

      Volume: 2016 Pages: 1-10

    • DOI

      10.1155/2016/7484872

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05264, KAKENHI-PROJECT-15K08788, KAKENHI-PROJECT-16K09114
  • [Journal Article] ヒトT細胞株への白石綿・青石綿継続曝露に伴う細胞特性の変化.2016

    • Author(s)
      李順姫,前田恵,松﨑秀紀,武井直子,山本祥子,幡山圭代,吉留 敬,西村泰光,大槻剛巳.
    • Journal Title

      日本予防医学雑誌

      Volume: 10 Pages: 119-125

    • NAID

      40020930413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Journal Article] Biological effects of Cloth containing specific ore powder in patients with pollen allergy.2016

    • Author(s)
      Lee, S., Okamoto, H., Yamamoto, S., Hatayama, T., Matsuzaki, H., Kumagai-Takei, N., Yoshitome, K., Nishimura, Y., Sato, T., Kirita, Y., Fujii, Y., Otsuki, T.
    • Journal Title

      Biomed. Environmental Sci.

      Volume: 29 Pages: 77-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Journal Article] FoxO1 Regulates Apoptosis Induced by Asbestos in the MT-2 Human T-Cell Line.2016

    • Author(s)
      Matsuzaki, H., Lee, S., Maeda, M., Kumagai-Takei, N., Nishimura, Y., Otsuki, T.
    • Journal Title

      Immunotoxicol.

      Volume: 13 Pages: 1-8

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Journal Article] Functional alteration of natural killer cells and cytotoxic T lymphocytes upon asbestos exposure and in malignant mesothelioma patients2015

    • Author(s)
      Nishimura Y, Kumagai-Takei N, Matsuzaki H, Lee S, Maeda M, Kishimoto T, Fukuoka K, Nakano T, and Otsuki T
    • Journal Title

      BioMed Res Int

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Journal Article] Investigating methods regarding diagnostic and prognostic biomarkers for malignant mesothelioma.2015

    • Author(s)
      Matsuzaki, H., Lee, S., Kumagai-Takei, N., Yoshitome, K., Yamamoto S, Hatayama T, Nishimura, Y., Otsuki, T.
    • Journal Title

      Kawasaki Med. J.

      Volume: 41 Pages: 13-22

    • NAID

      110009926233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Journal Article] Enhancement of regulatory T cell-like suppressive function in MT-2 by long-term and low-dose exposure to asbestos.2015

    • Author(s)
      Ying, C., Maeda, M., Nishimura, Y., Kumagai-Takei, N., Hayashi, H., Matsuzaki, H., Lee, S., Yoshitome, K., Yamamoto, S., Hatayama, T., Otsuki, T.
    • Journal Title

      Toxicology

      Volume: 338 Pages: 86-94

    • DOI

      10.1016/j.tox.2015.10.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Journal Article] Targeting LDH enzymes with a stiripentol analog to treat epilepsy.2015

    • Author(s)
      Sada N, Lee S, Katsu T, Otsuki T, Inoue T
    • Journal Title

      Science

      Volume: 347 Issue: 6228 Pages: 1362-1367

    • DOI

      10.1126/science.aaa1299

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590114, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25253008
  • [Journal Article] Exposure to negaively-charged particle domitant air-conditions on human lymphocytes in vitro activates immunological responses.2015

    • Author(s)
      Nishimura, Y., Takahashi, K., Masae, A., Kotani, M., Ami, K., Maeda, M., Shirahama, T., Lee, S., Matsuzaki, H., Kumagai-Takei, N., Yoshitome, K., Otsuki, T.
    • Journal Title

      Immunobiology

      Volume: 220 Issue: 12 Pages: 1359-1368

    • DOI

      10.1016/j.imbio.2015.07.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Journal Article] Enhancement of NK Cell Cytotoxicity Induced by Long-Term Living in Negatively Charged-Particle Dominant Indoor Air-Conditions.2015

    • Author(s)
      Nishimura, Y., Takahashi, K., Mase, A., Kotani, M., Ami, K., Maeda, M., Shirahama, T., Lee, S., Matsuzaki, H., Kumagai-Takei, N., Yoshitome, K., Otsuki, T.
    • Journal Title

      PlosOne

      Volume: 10 Issue: 7 Pages: e0132373-e0132373

    • DOI

      10.1371/journal.pone.0132373

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Journal Article] Functional alteration of natural killer cells and cytotoxic T lymphocytes upon asbestos exposure and in malignant mesothelioma patients.2015

    • Author(s)
      Nishimura, Y., Kumagai-Takei, N., Matsuzaki, H., Lee, S., Maeda, M., Kishimoto, T., Fukuoka, K., Nakano, T., Otsuki, T.
    • Journal Title

      Biomed. Res. Int.

      Volume: 2015 Pages: 1-9

    • DOI

      10.1155/2015/238431

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08788, KAKENHI-PROJECT-25860470
  • [Journal Article] Silica exposure and altered regulation of autoimmunity2014

    • Author(s)
      Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Maeda M, Chen Y, Kusaka M, Urakami K, Hayashi H, Fujimoto W, Nishimura Y, Otsuki T,
    • Journal Title

      Environ Health Prev Med

      Volume: 19 Issue: 5 Pages: 322-9

    • DOI

      10.1007/s12199-014-0403-9

    • NAID

      50009312838

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
  • [Journal Article] 【レギュラトリーT細胞の機能発現】 制御性T細胞機能へのアスベスト曝露影響2014

    • Author(s)
      西村泰光, 三浦由恵, 前田恵, 松崎秀紀, 李順姫, 武井直子, 大槻剛巳
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 62 Pages: 366-70

    • Data Source
      KAKENHI-PROJECT-24590770
  • [Journal Article] Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-immortalized T cell line MT-2.2014

    • Author(s)
      Maeda M, Chen Y, Hayashi H, Kumagai-Takei N, Matsuzaki H, Lee S, Nishimura Y, Otsuki T.
    • Journal Title

      Int J Oncol.

      Volume: 45 Issue: 6 Pages: 2522-2532

    • DOI

      10.3892/ijo.2014.2682

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24580494, KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
  • [Journal Article] アスベスト曝露によるTh1細胞機能の低下2014

    • Author(s)
      西村泰光, 前田恵, 三浦由恵, 松崎秀紀, 李順姫, 武井直子, 大槻剛巳
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 62 Pages: 314-17

    • NAID

      40020210778

    • Data Source
      KAKENHI-PROJECT-24590770
  • [Journal Article] Functional properties of CD8+ lymphocytes in patients with pleural plaque and malignant mesothelioma2014

    • Author(s)
      Kumagai-Takei N, Nishimura Y, Maeda M, Hayashi H, Matsuzaki H, Lee S, Kishimoto T, Fukuoka K, Nakano T, and Otsuki T
    • Journal Title

      J Immunol Res

      Volume: 2014 Pages: 10-20

    • DOI

      10.1155/2014/670140

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860470, KAKENHI-PROJECT-25860471
  • [Journal Article] 【抗腫瘍免疫の抑制と活性化】 アスベストによる抗腫瘍免疫の抑制2014

    • Author(s)
      西村泰光, 武井直子, 松崎秀紀, 李順姫, 大槻剛巳
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 61 Pages: 585-91

    • Data Source
      KAKENHI-PROJECT-24590770
  • [Journal Article] 珪酸曝露による免疫影響2014

    • Author(s)
      松崎秀紀, 前田恵, 林宏明, 武井直子, 李順姫, 吉留敬, 草加勝康, 浦上更三, 西村泰光, 兵藤文則, 大槻剛巳
    • Journal Title

      日本予防医学会雑誌

      Volume: 9 Pages: 1-8

    • NAID

      40020166317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Journal Article] Effect of asbestos exposure on differentiation of cytotoxic T lymphocytes in MLR of human PBMCs2013

    • Author(s)
      Kumagai-takei N, Nishimura Y, Maeda M, Hayashi H, Matsuzaki H, Lee S, Hiratsuka J, Otsuki T
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 49(1) Issue: 1 Pages: 28-36

    • DOI

      10.1165/rcmb.2012-0134oc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25293267, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
  • [Journal Article] Exploration of biomarkers for asbestos exposure and occurrence of malignant mesothelioma based on the immunological effects of asbestos2013

    • Author(s)
      Matsuzaki H, Lee S, Kumagai-Takei N, Hayashi H, Miura Y, Chen Y, Maeda M, Yamamoto S, Hatayama T, Nishimura Y, Otsuki T
    • Journal Title

      J Postgenomics: Drug & Biomarker Dev

      Volume: S2 Issue: 02 Pages: 1-6

    • DOI

      10.4172/2153-0602.s2-001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825
  • [Journal Article] Alteration of cytoskeletal molecules in a human T cell line caused by continuous exposure to chrysotile asbestos.2013

    • Author(s)
      Maeda, M., Chen, Y., Kumagai-Takei, N., Hayashi, H., Matsuzaki, H., Lee, S., Hiratsuka, JI., Nishimura, Y., Kimura, Y., Otsuki T.
    • Journal Title

      Immunobiology

      Volume: (in press) Issue: 9 Pages: 1184-91

    • DOI

      10.1016/j.imbio.2013.04.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25293267, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
  • [Journal Article] Altered functions of alveolar macrophages and NK cells involved in asbestos-related diseases.2013

    • Author(s)
      Nishimura, Y., Maeda, M.,Kumagai-Takei, N., Lee, S., Matsuzaki, H., Wada, Y., Nishiike-Wada, T., Iguchi, H., Otsuki, T.
    • Journal Title

      Environ. Health Prev. Med.

      Volume: 18(3) Issue: 3 Pages: 198-204

    • DOI

      10.1007/s12199-013-0333-y

    • NAID

      10031175980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
  • [Journal Article] Resistance to asbestos-induced apoptosis with continuous exposure to crocidolite ona human T cell.2012

    • Author(s)
      Maeda, M., Yamamoto, S., Chen, Y.,Kumagai-Takei, N., Hayashi, H., Matsuzaki, H., Lee, S., Hatayama, T., Miyahara, N., Katoh, M., Hiratsuka, J., Nishimura, Y., Otsuki, T.
    • Journal Title

      Sci. Total Environ.

      Volume: 429 Pages: 174-182

    • DOI

      10.1016/j.scitotenv.2012.04.043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770
  • [Journal Article] Asbestos-induced cellular and molecular alteration of immunocompetent cells and the relationship with chronic inflammation and carcinogenesis2012

    • Author(s)
      Matsuzaki Hidenori
    • Journal Title

      Journal of Biomedicine and Biotechnology

      Volume: 2012 Pages: 1-9

    • DOI

      10.1155/2012/492608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700933, KAKENHI-PROJECT-22790550, KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770
  • [Journal Article] Environmental factors producing autoimmune dysregulation-Chronic activation of T cells caused by silica exposure2012

    • Author(s)
      Suni Lee
    • Journal Title

      Immunobiology

      Volume: (Epub ahead of print) Issue: 7 Pages: 43-48

    • DOI

      10.1016/j.imbio.2011.12.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790550, KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770
  • [Patent] 自己免疫異常の検査方法2020

    • Inventor(s)
      李順姫, 大槻剛巳
    • Industrial Property Rights Holder
      李順姫, 大槻剛巳
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Acquisition Date
      2021
    • Data Source
      KAKENHI-PROJECT-20K10437
  • [Patent] 自己免疫異常の検査方法2017

    • Inventor(s)
      大槻剛巳、西村泰光、李順姫
    • Industrial Property Rights Holder
      川崎医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-192501
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-17K09171
  • [Presentation] 主成分分析による悪性中皮腫のニボルマブ治療効果に関わる免疫動態の評価2022

    • Author(s)
      西村泰光, 李順姫, 武井直子, 伊藤達男, 上月稔幸, 藤本伸一, 大槻剛巳
    • Organizer
      第92回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] 悪性中皮腫患者末梢血の免疫学的特徴とニボルマブ治療効果との関連2021

    • Author(s)
      西村泰光, 李順姫, 武井直子, 伊藤達男, 藤本伸一, 上月稔幸, 大槻剛巳
    • Organizer
      第28回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] 珪酸曝露によるヒト末梢血単核球における遺伝子発現およびサイトカイン分泌の解析2021

    • Author(s)
      李順姫, 西村泰光, 大槻剛巳
    • Organizer
      第28回 日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-20K10437
  • [Presentation] チタン酸ナノシートの毒性機序における細胞内Ca2+増加を介したリソソーム制御不全2021

    • Author(s)
      西村泰光, 吉岡大輔, 武井直子, 李順姫, 吉留敬, 伊藤達男, 大槻剛巳
    • Organizer
      第91回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19714
  • [Presentation] 悪性中皮腫患者におけるニボルマブ投与前後の血漿中サイトカイン濃度の変化2021

    • Author(s)
      西村泰光, 武井直子, 李順姫, 伊藤達男, 藤本伸一, 上月稔幸
    • Organizer
      第94回日本産業衛生学会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] トランスクリプトーム解析による石綿曝露に共通する細胞傷害性T細胞の遺伝子発現変動および石綿種間での差異の探索2021

    • Author(s)
      西村泰光, 武井直子, 李順姫, 伊藤達男, 大槻剛巳
    • Organizer
      第48回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] 悪性中皮腫患者におけるニボルマブ投与前後の包括的免疫機能解析2021

    • Author(s)
      西村泰光, 李順姫, 武井直子, 伊藤達男, 藤本伸一, 上月稔幸, 大槻剛巳
    • Organizer
      第2回日本石綿・中皮腫学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] Titanate nanosheets cause vacuolar ATPase-dependent apoptosis of human monocytes through lysosomal toxicity not related with augmented autophagy2020

    • Author(s)
      Y. Nishimura, D. Yoishioka, N. Kumagai-Takei, S. Lee, K. Yoshitome, and T. Otsuki
    • Organizer
      Society of Toxicology (SOT) 59th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19714
  • [Presentation] 石綿曝露下CTL分化抑制時の補助刺激分子の役割2020

    • Author(s)
      武井直子、西村泰光、李順姫、吉留敬、伊藤達男、大槻剛巳
    • Organizer
      第90回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] ヒトCD8+T細胞株において石綿長期曝露で発現変動する転写産物の網羅的探索2020

    • Author(s)
      西村泰光, 武井直子, 李順姫, 吉留敬, 伊藤達男, 大槻剛巳
    • Organizer
      第93回日本産業衛生学会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] 石綿継続曝露T細胞における石綿誘導性細胞死忌避メカニズムの探索2020

    • Author(s)
      李順姫、山本祥子、松﨑秀紀、幡山圭代、武井直子、吉留敬、伊藤達男、西村泰光、大槻剛巳
    • Organizer
      第90回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] チタン酸ナノシートの毒性機序におけるリソソーム由来Ca2+シグナリングの役割2020

    • Author(s)
      西村泰光, 吉岡大輔, 武井直子, 李順姫, 吉留敬, 伊藤達雄, 大槻剛巳
    • Organizer
      第47回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-18K19714
  • [Presentation] 長期石綿曝露ヒトTリンパ球細胞株のトランスクリプトーム解析2020

    • Author(s)
      西村泰光、武井直子、李順姫、吉留敬、伊藤達男、大槻剛巳
    • Organizer
      第90回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] 石綿長期曝露ヒト制御性T細胞モデル株におけるMM7発現の更新と機能解析2020

    • Author(s)
      李順姫、山本祥子、幡山圭代、伊藤達男、武井直子、吉留敬、西村泰光、大槻剛巳
    • Organizer
      第27回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] 石綿曝露によるCTL分化抑制における補助刺激分子の役割2020

    • Author(s)
      武井直子、西村泰光、吉留敬、李順姫、伊藤達男、大槻剛巳
    • Organizer
      第27回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] チタン酸ナノシートの細胞毒性における小胞酸性化と液胞型ATPアーゼ依存性2019

    • Author(s)
      西村 泰光, 吉岡 大輔, 武井 直子, 李 順姫, 吉留 敬, 大槻 剛巳
    • Organizer
      第46回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-18K19714
  • [Presentation] Immunological screening devices for patients with malignant mesothelioma as well as people exposure to asbestos2019

    • Author(s)
      Nishimura Y. Kumagai-Takei N, Lee S, Matsuzaki H, Yoshitome K, Kishimoto T, Fukuoka K, Tabata C, Nakano T, Otsuki T.
    • Organizer
      The 18th International Conference of the Pacific Basin Consortium for Environment and Health (PBC) titled Assessing and Mitigating Environmental Exposures in Early Life
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] 珪酸曝露下の免疫細胞におけるTLR刺激応答と自己免疫疾患関連分子の探索2019

    • Author(s)
      李順姫、山本祥子、幡山圭代、松﨑秀紀、武井奈子、吉留敬、西村泰光、大槻剛巳
    • Organizer
      第89回日本衛生学会
    • Data Source
      KAKENHI-PROJECT-17K09171
  • [Presentation] ヒト単球へのチタン酸ナノシートのv-ATPase依存的リソソーム毒性2019

    • Author(s)
      西村泰光、吉岡大輔、武井直子、李順姫、吉留敬、大槻剛巳
    • Organizer
      第89回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19714
  • [Presentation] CD4+ T Cell-Derived Factors Prevent Asbestos-Caused Suppression of Mesothelial Cell Growth2019

    • Author(s)
      Nishimura Y, Kumagai-Takei N, Lee S, Yoshitome K, Otsuki T
    • Organizer
      The 58th Annual Meeting of the Society of Toxicology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] Comprehensive analysis for immunological characteristics of patients with malignant mesothelioma and diffuse pleural thickening2019

    • Author(s)
      Nishimura Y, Lee S, Kumagai-Takei N, Mastuzaki H, Yoshitome K, Okamoto K, Kishimoto T, Otsuki T
    • Organizer
      The XV International Congress of Toxicology (ICTXV)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] チタン酸ナノシートの毒性機序におけるTRPMLチャンネルの関与2019

    • Author(s)
      西村 泰光, 吉岡 大輔, 李 順姫, 武井 直子, 吉留 敬, 伊藤 達雄, 大槻 剛巳
    • Organizer
      第90回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19714
  • [Presentation] 活性化CD4+Tリンパ球由来因子による石綿曝露下の中皮細胞増殖抑制への干渉2019

    • Author(s)
      西村泰光、武井直子、李順姫、吉留敬、大槻剛巳
    • Organizer
      第89回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] 珪肺症と自己免疫疾患2019

    • Author(s)
      李順姫、武井直子、吉留敬、西村泰光、大槻剛巳
    • Organizer
      第46回日本毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09171
  • [Presentation] ヒトCD8+T細胞株における石綿曝露日数依存的IFN-γ mRNAレベルの漸減2019

    • Author(s)
      西村泰光、武井直子、李順姫、吉留敬、大槻剛巳
    • Organizer
      第92回日本産業衛生学会
    • Data Source
      KAKENHI-PROJECT-19H03892
  • [Presentation] Induction of IL-17 production from human peripheral blood CD4+ cells by asbestos exposure2018

    • Author(s)
      Otsuki T, Maeda M, Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Nishimura Y
    • Organizer
      ICOH (International Congress on Occupational Health) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] チタン酸ナノシート曝露によるヒト単球培養時のオートファジー関連遺伝子発現量変化2018

    • Author(s)
      西村泰光、吉岡大輔、武井直子、李順姫、吉留敬、大槻剛巳
    • Organizer
      第25回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-18K19714
  • [Presentation] Effects of IL-15 addition on the suppressed induction of CTL upon exposure to asbestos2018

    • Author(s)
      Kumagai-Takei N, Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Otsuki T
    • Organizer
      ICOH (International Congress on Occupational Health) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] Augmented prioliferation of mesothelial cells caused by secretory factors derived from immune cells upon exposure to asbestos2018

    • Author(s)
      Nishimura Y, Maki Y, Kumagai-Takei N, Lee S, Matsuzaki H, Yosahitome K, Otsuki T
    • Organizer
      ICOH (International Congress on Occupational Health) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] Nanotoxicity of titanium nanosheets for human immune cells2018

    • Author(s)
      Nishimura Y, Yoshioka D, Kumagai-Takei N, Matsuzaki H, Lee S, Yoshitome K, Otsuki T
    • Organizer
      ICOH (International Congress on Occupational Health) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19714
  • [Presentation] The Functional Analysis of Human CD8+ T Cell Line with Long-Term Exposure to Chrysotile Asbestos Fibers2018

    • Author(s)
      Kumagai-Takei N. Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Otsuki T
    • Organizer
      The 57th Annual Meeting of the Society of Toxicology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] Search for biomarkers of asbestos exposure and asbestos-induced cancers in investigations of the immunological effects of asbestos2018

    • Author(s)
      Otsuki T, Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Nishimura Y
    • Organizer
      ICOH (International Congress on Occupational Health) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] Scores predictive for asbestos exposure, malignant mesothelioma and pleural plaque on the basis of comprehensive immunological analysis2018

    • Author(s)
      Nishimura Y, Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Nakno T, Kishimoto T, Otsuki T
    • Organizer
      ICOH (International Congress on Occupational Health) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] Effet of long-term exposure to asbestos on functional properties of human CD8+ T cell line2018

    • Author(s)
      Kumagai-Takei N, Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Otsuki T
    • Organizer
      ICOH (International Congress on Occupational Health) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] Difference in Immunological Characteristics between Patients with Malignant Mesothelioma and Diffuse Pleural Thickening2018

    • Author(s)
      Yasumitsu Nishimura, Suni Lee, Naoko Kumagai-Takei, Hidenori Matsuzaki, Kei Yoshitome, Takemi Otsuki
    • Organizer
      The 57th Annual Meeting of the Society of Toxicology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] Clinical evaluation of CENP-B and Scl-70 autoantibodies in silicosis patients.2018

    • Author(s)
      Suni Lee
    • Organizer
      International Congress on Occupational Health (ICOH2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09171
  • [Presentation] Effect of Short-Term and Long-Term Exposure of Asbestos on Human T Cell Line MT-2.2017

    • Author(s)
      Matsuzaki, H., Lee, S., Maeda, M., Kumagai-Takei, N., Yoshitome, K., Nishimura, Y., Otsuki, T.
    • Organizer
      The 56th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      The Baltimore Convention Center (Baltimore, Maryland, USA)
    • Year and Date
      2017-03-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Presentation] 悪性中脾腫患者とびまん性胸膜肥厚患者の包括的免疫機能解析2017

    • Author(s)
      西村泰光、李順姫、武井直子、松﨑秀紀、岡本賢三、岸本卓巳、大槻剛巳
    • Organizer
      第88回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] Apoptosis of monocytes with giant vacuoles related to disruption in endosomal pathway caused by titanate nanosheets2017

    • Author(s)
      Nishimura Y, Kumagai-Takei N, Lee S, Matsuzaki H, Yoshitome K, Otsuki T
    • Organizer
      The British Society for Immunology Congress 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15245
  • [Presentation] Increased Proliferation of Mesothelial Cells under the Influence of Asbestos-Exposed Peripheral Blood Mononuclear Cells2017

    • Author(s)
      Nishimura Y. Maki Y, Tooyoka S, Kumagai-Takei N, Lee S, Matsuzaki H, Otsuki T
    • Organizer
      The 56th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Baltimore Convention Center, Baltimore, USA
    • Year and Date
      2017-03-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] 免疫細胞由来因子により引き起こされるヒト中皮細胞増殖脳の石綿耐性2017

    • Author(s)
      西村泰光,李順姫,武井直子,松﨑秀紀,吉留敬,大槻剛巳
    • Organizer
      第87回日本衛生学会学術総会
    • Place of Presentation
      フェニックス・シーガイア・リゾート, 宮崎県, 宮崎市
    • Year and Date
      2017-03-27
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] 珪肺症における自己免疫疾患発症をもたらす増悪因子の検討2017

    • Author(s)
      李順姫
    • Organizer
      川崎医科大学学術集会
    • Data Source
      KAKENHI-PROJECT-17K09171
  • [Presentation] Continuous and low-dose exposure to asbestos on human T cells causes reduction of anti-tumor immunity2017

    • Author(s)
      Otsuki T, Maeda M, Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Sada N, Nishimura Y
    • Organizer
      International Conference on Environmental Health and Environmental-related Cancer Prevention 2017: Assessing low-doses and cumulative effects of exposure to chemical mixtures
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] アスベスト曝露により誘導されるストレス応答の研究2017

    • Author(s)
      松﨑秀紀、李順姫、前田 恵、武井直子、吉留 敬、西村泰光、大槻剛巳
    • Organizer
      第24回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Presentation] MT-2細胞に対する短期および長期のアスベスト曝露の影響の研究2017

    • Author(s)
      松﨑秀紀,李順姫,前田恵,武井直子,西村泰光,吉留敬,大槻剛巳
    • Organizer
      第87回日本衛生学会学術総会
    • Place of Presentation
      フェニックス・シーガイア・リゾート(宮崎県宮崎市)
    • Year and Date
      2017-03-26
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Presentation] The immunological screening devices for human malignant mesothelioma and asbestos exposure2017

    • Author(s)
      Nishimura Y, Lee S, Kumagai-Takei N, Mastuzaki H, Yoshitome K, Otsuki T
    • Organizer
      The 27th Japan Korea China Conference on Occupational Health
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] チタン酸ナノシート曝露によるヒトPBMCのア ポトーシスと単球における巨大空胞形成2017

    • Author(s)
      西村泰光,吉岡大輔,李順姫,武井直子,松崎秀紀,吉留敬,大槻剛巳
    • Organizer
      第90回日本産業衛生学会
    • Data Source
      KAKENHI-PROJECT-15K15245
  • [Presentation] Titanate nanosheets cause caspase-dependent apoptosis of human immune cells with giant vacuole formation through endosomal defect in monochytes2017

    • Author(s)
      Nishimura Y, Yoshioka D, Kumagai-Takei N, Lee S, Matsuzaki H, Yoshitome K, Otsuki T
    • Organizer
      The 53rd Congress of the European Societies of Toxicology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15245
  • [Presentation] Vacuole Formation And Caspase-dependent Apoptosis In Human Monocytes Caused By Exposure To Titanate Nanosheet2016

    • Author(s)
      Nishimura Y, Yoshioka D, Lee S, Kumagai-Takei N, Matsuzaki H, Yoshitome K, Otsuki T
    • Organizer
      The 55th Annual Meeting. Society of Toxicology
    • Place of Presentation
      New Orleans Ernest N. Morial Convention Center (New Orleans, Louisiana)
    • Year and Date
      2016-03-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15245
  • [Presentation] 悪性中皮腫スクリーニングデバイスとしての免疫学的スコア式の開発2016

    • Author(s)
      西村泰光,李順姫,武井直子,吉留敬,岸本卓巳,福岡和也,田端千春,中野孝司,大槻剛巳
    • Organizer
      第89回日本産業衛生学会
    • Place of Presentation
      福島県文化センター, 福島県, 福島市
    • Year and Date
      2016-05-26
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] The Role of Transcription Factor FoxP3 in the Asbestos-Induced Apoptosis in MT-2 Cells.2016

    • Author(s)
      Matsuzaki H. Lee S, Maeda M, Kumagai-Takei N, Yoshitome K, Nishimura Y, Otsuki T.
    • Organizer
      The 55th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Ernest N. Morial Convention Center, New Orleans, USA
    • Year and Date
      2016-03-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Presentation] MT-2 細胞を用いた短期および長期のアスベスト曝露の影響の解析2016

    • Author(s)
      松﨑秀紀,李順姫,前田恵,武井直子,西村泰光,大槻剛巳
    • Organizer
      第23回日本免疫毒性学会学術年会
    • Place of Presentation
      北九州国際会議場(福岡県北九州市)
    • Year and Date
      2016-09-05
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Presentation] アスベスト曝露と悪性中皮腫に関わる免疫学的特徴の解析とスクリーニングデバイスの開発2016

    • Author(s)
      西村泰光,李順姫,武井直子,松﨑秀紀,吉留敬,大槻剛巳
    • Organizer
      第23回日本免疫毒性学会学術年会
    • Place of Presentation
      北九州国際会議場, 福岡県, 北九州市
    • Year and Date
      2016-09-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05264
  • [Presentation] 空砲形成を伴う細胞死を惹起するチタン酸ナノシートの単球への取り込みと細胞内動態2016

    • Author(s)
      西村泰光, 吉岡大輔, 李順姫, 武井直子, 松崎秀紀, 吉留敬, 大槻剛巳
    • Organizer
      第86回日本衛生学会学術総会
    • Place of Presentation
      旭川市民文化会館, 北海道, 旭川市
    • Year and Date
      2016-05-13
    • Data Source
      KAKENHI-PROJECT-15K15245
  • [Presentation] Study for Immunological Importance of Increased Plasma Decoy Receptor 3 Level in Silicosis2016

    • Author(s)
      Lee S. Nishimura Y, Yamamoto S, Hatayama T, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Hayashi H, Uragami K, Kusaka M, Fujimoto W, Otsuki T.
    • Organizer
      The 55th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      New Orleans, Louisiana, U.S.A.
    • Year and Date
      2016-03-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] The characteristic cell death of human monocytes caused by exposure to nano-sized and sheet-like titanate2015

    • Author(s)
      西村泰光, 武井直子, 松崎秀紀, 李順姫, 大槻剛巳
    • Organizer
      第44回日本免疫学会学術集会
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-15K15245
  • [Presentation] 珪肺症患者由来血漿における自己抗体および液性因子の解析2015

    • Author(s)
      李順姫
    • Organizer
      第6回川崎医科大学学術集会
    • Place of Presentation
      川崎医科大学M-800教室・7/8F学生教員ラウンジ(倉敷)
    • Year and Date
      2015-08-01
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] チタン酸ナノシート曝露による単球の空胞形成と細胞死2015

    • Author(s)
      西村泰光, 吉岡大輔, 李順姫, 武井直子, 松崎秀紀, 吉留敬, 大槻剛巳
    • Organizer
      第22回日本免疫毒性学会学術年会
    • Place of Presentation
      京都大学百周年時計台記念館国際交流ホール(京都)
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-15K15245
  • [Presentation] Role of FoxO1 and FoxP3 in Asbestos-induced Apoptosis of MT-2 Cells.2015

    • Author(s)
      Matsuzaki H, Lee S, Maeda M, Kumagai-Takei N, Nishimura Y, Otsuki T.
    • Organizer
      31st International Congress on Occupational Health
    • Place of Presentation
      COEX Convention Center, Seoul, Korea
    • Year and Date
      2015-06-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Presentation] 自己免疫疾患未発症珪肺症例における血漿免疫グロブリンとBAFF値の解析2015

    • Author(s)
      李順姫,西村泰光,山本祥子,幡山圭代,松崎秀紀,武井直子,吉留敬,大槻剛巳.
    • Organizer
      第22回日本免疫毒性学会学術年会
    • Place of Presentation
      京都大学百周年時計台記念館国際交流ホール(京都)
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] FoxP3 に対するアスベスト長期曝露影響の解析2015

    • Author(s)
      松﨑秀紀,李順姫,前田恵,武井直子,西村泰光,大槻剛巳
    • Organizer
      第22回日本免疫毒性学会学術年会
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K08788
  • [Presentation] Analysis between blood DcR3 level, autoantibodies and respiratory score in silicosis patients.2015

    • Author(s)
      Lee S, Nishimura Y, Yamamoto S, Hatayama T, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Otsuki T.
    • Organizer
      31st ICOH (International Congress on Occupational Health)
    • Place of Presentation
      COEX Convention Center, Seoul, Korea
    • Year and Date
      2015-05-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] 珪肺症における免疫異常:血漿 Decoy Receptor 3 の位置付け診断指標の構築2015

    • Author(s)
      大槻剛巳,李順姫,武井直子,松崎秀紀,吉留敬,西村泰光,林宏明,浦上更三,草加勝康,藤本亘
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      ANAクラウンプラザホテル金沢など(金沢)
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] Differences of immunological effects of crystalline silica and asbestos fibers on regulatory T cell2015

    • Author(s)
      Lee S, Otsuki T.
    • Organizer
      The 54th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      San Diego Convention Center in San Diego, California, 米国
    • Year and Date
      2015-03-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] 珪肺症における血清DcR3分子の病態における位置付け2015

    • Author(s)
      李順姫,大槻剛巳,松崎秀紀,武井直子,吉留敬,西村泰光,草加勝康,浦上更三
    • Organizer
      第59回中国四国合同産業衛生学会
    • Place of Presentation
      愛媛大学城北キャンパス南加記念ホール(松山)
    • Year and Date
      2015-12-05
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] 珪肺症例における血漿DcR3値と各種自己免疫疾患関連因子との相関性の検討2014

    • Author(s)
      李 順姫,西村泰光,山本祥子,幡山圭代,松崎秀紀,武井直子,大槻剛巳.
    • Organizer
      第13回分子予防環境医学研究会
    • Place of Presentation
      和歌山県民文化会館 大会議室
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] Analysis of blood DcR3 concentration andits correlation to clinical paramaters of autoimmune diseases in silicosis patients.2014

    • Author(s)
      Lee S, Nishimra Y, Yamamoto S, Hatayama T, Mastuzaki H, Kumagai-Takei N, Hayashi H, Kusaka M, Fujimoto W, Otsuki T.
    • Organizer
      The 53rd annual Meeting. Society of Toxicology
    • Place of Presentation
      Phoenix, AZ, USA
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] 悪性中皮腫患者および胸膜プラーク陽性者の末梢血における免疫学的特徴2014

    • Author(s)
      西村泰光, 李順姫, 武井直子, 松﨑秀紀, 岸本卓巳, 福岡和也,田端千春, 中野孝司, 大槻剛巳
    • Organizer
      第5回JMIG (Japan Mesothelioma Interest Group)研究会
    • Place of Presentation
      京都(京都私学会館)
    • Year and Date
      2014-09-20
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] Long-term exposure of asbestos affects cell cycle and cell death in Treg model cell line MT-2.2013

    • Author(s)
      Lee S, Matsuzaki H, Maeda M, Kumagai-Takei N, Nishimura Y, Otsuki T.
    • Organizer
      6th International Symposium on Nanotechnology, Occupational and Environmental Health.
    • Place of Presentation
      Nagoya Congress Center
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] Effects of asbestos exposure on regulatory role of NK cells for expanded autologous CD4+ T cells2013

    • Author(s)
      Nishimura Y, Kumagai-Takei N, Matsuzaki H, Lee S, Otsuki T
    • Organizer
      The 52nd Annual Meeting, Society of Toxicology
    • Place of Presentation
      Henry B. Gonzalez Convention Center (San Antonio, Texas)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] 悪性中皮腫および全身性強皮症患者における免疫関連遺伝子発現動態の解析2013

    • Author(s)
      西村泰光,李順姫,武井直子,松﨑秀紀,林宏明,藤本亘,守田吉孝,岸本卓巳,大槻剛巳
    • Organizer
      第83回日本衛生学会
    • Place of Presentation
      金沢大学(金沢)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] 石綿長期曝露制御性T細胞株における細胞周期制御因子の発現動態の解析2013

    • Author(s)
      李順姫,松﨑秀紀,武井直子,西村泰光,大槻剛巳.
    • Organizer
      第20回石綿・中皮腫研究会
    • Place of Presentation
      東京、(公財)がん研究会がん研究所 吉田講堂
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] Continuous exposure of asbestos on Treg model cell line MT-2 affects cellcycle progression and cell surbvival.2013

    • Author(s)
      Lee S, Matsuzaki H, Maeda M, Kumagai-Takei N, Nishimura , Otsuki T.
    • Organizer
      2013日本免疫学会・学術集会
    • Place of Presentation
      千葉、幕張メッセ
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] 末梢血中の多項目サイトカイン濃度測定に基づく悪性中皮腫診断指標構築2012

    • Author(s)
      西村泰光,武井直子,松﨑秀紀,李順姫,大槻剛巳
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] 免疫学的所見に基づくアスベスト曝露者の病態解析と診断指標構築の試み<シンポジウム「免疫毒性学研究の進歩」>2012

    • Author(s)
      西村泰光,武井直子,松﨑秀紀,李順姫,前田恵,岸本卓巳,大槻剛巳
    • Organizer
      第19回日本免疫毒性学会
    • Place of Presentation
      東京慈恵会医科大学(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] Carbon nanotubes-indued decrease in cytotoxicity of NK cells with altered expression of NK cell-activating receptors2012

    • Author(s)
      Nishimura Y, Kumagai-Takei N, Matsuzaki H, Lee S, Maeda M, Otsuki T
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸国際会議場・神戸国際展示場(神戸)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] マイナス荷電粒子優位な室内環境の免疫影響2011

    • Author(s)
      大槻剛巳, 高橋一聡, 真鍋弘穀, 小谷宗男, 前田恵, 熊谷直子, 松崎秀紀, 李順姫, 西村泰光
    • Organizer
      第18回日本免疫毒性学会
    • Place of Presentation
      千葉大学けやき会館(千葉県)
    • Data Source
      KAKENHI-PROJECT-21659161
  • [Presentation] 石綿の低濃度長期曝露がTreg様モデル細胞株 MT-2細胞の細胞増殖に及ぼす影響

    • Author(s)
      李順姫,松崎秀紀,前田恵,武井直子,西村泰光,大槻剛巳.
    • Organizer
      第87回日本産業衛生学会
    • Place of Presentation
      岡山コンベンションセンター(岡山)
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] 自己免疫疾患未発症珪肺症例にいおける血中DcR3値と他の自己抗体値や呼吸機能検査値との関連

    • Author(s)
      李順姫,西村泰光,山本祥子,幡山圭代,松﨑秀紀,武井直子,吉留敬,大槻剛巳.
    • Organizer
      第21回日本免疫毒性学会学術年会
    • Place of Presentation
      徳島文理大学・国際会議場、徳島
    • Year and Date
      2014-09-11 – 2014-09-12
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] Functional Characteristics of Immune Cells in Peripheral Blood of Individuals with Pleural Plaque and Patients with Malignant Mesothelioma

    • Author(s)
      Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Yoshitome K, Otsuki T
    • Organizer
      The 54th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      San Diego, (San Diego Convention Center)
    • Year and Date
      2015-03-22 – 2015-03-26
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] 珪肺症例における血漿中DcR3値と各種自己免疫疾患関連因子との相関性の検討

    • Author(s)
      李順姫,西村泰光,松崎秀紀,武井直子,山本祥子,幡山圭代,大槻剛巳.
    • Organizer
      第84回日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター、岡山
    • Year and Date
      2014-05-25 – 2014-05-27
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] The characteristics of activated lymphocytes in silicosis differing in Th17 phenotype from systemic sclerosis

    • Author(s)
      Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Hayashi H, Fujimoto W, Morita Y, Kusaka M, Otsuki T
    • Organizer
      The 53rd annual Meeting. Society of Toxicology
    • Place of Presentation
      Poenix Convention Center (Phoenix, Arizona)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] チタン酸ナノシートの末梢血単核球に対する毒性影響

    • Author(s)
      西村泰光,吉岡大輔,李順姫,武井直子,松﨑秀紀,大槻剛巳
    • Organizer
      第20回日本免疫毒性学会学術年会
    • Place of Presentation
      東海大学代々木キャンパス (東京)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] Immunological analysis for patients with silicosis or systemic scleroderma

    • Author(s)
      Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Otsuki T
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      幕張メッセ (千葉)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] Immunological similarity and difference observed in analyses for mRNAs, cell surface molecules and plasma cytokines between silicosis and systemic scleroderma

    • Author(s)
      Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Yoshitome K, Otsuki T
    • Organizer
      The 21st Asian Conference on Occupational Health
    • Place of Presentation
      福岡(ヒルトン福岡シーホーク)
    • Year and Date
      2014-09-02 – 2014-09-04
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] 珪酸が黒関連疾患における免疫動態の包括的解析.(日本毒性学会・日本免疫毒性学会合同シンポジウム「次世代が切り拓く革新的免疫毒性研究」)

    • Author(s)
      西村泰光,李順姫,武井直子,松崎秀紀,大槻剛巳
    • Organizer
      第41回日本毒性学会学術年会
    • Place of Presentation
      神戸(神戸コンベンションセンター)
    • Year and Date
      2014-07-02 – 2014-07-04
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] 珪肺症と強皮症における免疫機能亢進の類似およびTh細胞機能の差違

    • Author(s)
      西村泰光,李 順姫, 武井直子, 松﨑秀紀, 藤本亘, 林宏明 , 守田吉孝 , 大槻剛巳
    • Organizer
      第13回分子予防環境医学研究会
    • Place of Presentation
      和歌山県民文化会館 (和歌山)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] Immunological similarity and difference between individuals positive for pleural plaque with malignant mesothelioma, rebealed by analysis for mRNA levels

    • Author(s)
      Nishimura Y, Lee S Kumagai-Takei N, Matsuzaki H, Otsuki T
    • Organizer
      The 43rd Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      京都(国立京都国際会館)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] Analysis of blood DcR3 concentration and its correlation to autoantibodies in silicosis patients.

    • Author(s)
      Lee S, Nishimura Y, Yamamoto S, Hatayama T, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Otsuki T.
    • Organizer
      The 21st The Asian Association for Occupational Health
    • Place of Presentation
      Hilton Fukuoka Sea Halk、福岡
    • Year and Date
      2014-09-02 – 2014-09-04
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] 胸膜プラーク陽性者の血漿および末梢血単核球における免疫学的特徴

    • Author(s)
      西村泰光,李順姫,武井直子,松﨑秀紀,前田恵, 岸本卓巳, 福岡和也, 中野孝司, 大槻剛巳
    • Organizer
      第4回JMIG研究会(Japan Mesothelioma Interest Group)
    • Place of Presentation
      京都私学会館 (京都)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] カーボンナノチューブ曝露によるNK細胞機能低下

    • Author(s)
      西村泰光,武井直子,松﨑秀紀,李順姫,平野靖史郎,大槻剛巳
    • Organizer
      第19回石綿・中皮腫研究会
    • Place of Presentation
      ホテル北野プラザ(神戸)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] Immunological characteristics in asbestos and silica-caused diseases

    • Author(s)
      Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Yoshitome K, Otsuki T
    • Organizer
      The 7th International Congress of Asian Society of Toxicology
    • Place of Presentation
      Jeju Island, Korea (International Convention Center Jeju Island )
    • Year and Date
      2015-06-23 – 2015-06-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] Plasma DcR3 which inhibits Fas-induced apoptosis is increased in silicosis patients who are non-onset autoimmune diseases.

    • Author(s)
      Lee S, Nishimura Y, Matsuzaki H, Kumagai-Takei N, Ostuki T.
    • Organizer
      The 43rd Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      京都国際会館、京都
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-25460825
  • [Presentation] 石綿曝露者および悪性中皮腫患者における免疫動態の解析

    • Author(s)
      西村泰光,李順姫,武井直子,松崎秀紀,岸本卓巳,大槻剛巳
    • Organizer
      第86回日本産業衛生学会
    • Place of Presentation
      ひめぎんホール (松山)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] Suppressive effects of exposure to multi-walled carbon nanotubes and asbestos on NK cell function

    • Author(s)
      Nishimura Y, Kumagai-Takei N, Mastuzaki H, Lee S, Otsuki T
    • Organizer
      6th International Symposium on Nanotechnology, Occupational and Environmental Health
    • Place of Presentation
      名古屋国際会議場 (名古屋)
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] 多面的免疫機能解析による珪肺と全身性強皮症の比較

    • Author(s)
      西村泰光,李順姫,武井直子,松崎秀紀,林宏明,藤本亘,守田吉孝,草加勝康,大槻剛巳
    • Organizer
      第87回日本産業衛生学会
    • Place of Presentation
      岡山(岡山コンベンションセンター)
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] 胸膜プラーク陽性者および悪性中皮腫患者末梢血の包括的免疫機能解析

    • Author(s)
      西村泰光,李順姫,武井直子,松崎秀紀,吉留敬,岸本卓巳,福岡和也,田端千春,中野考司,大槻剛巳
    • Organizer
      第85回日本衛生学会学術総会
    • Place of Presentation
      和歌山(和歌山県民文化会館)
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-24590770
  • [Presentation] 珪酸・アスベストの免疫影響

    • Author(s)
      西村泰光,武井直子,李順姫,松崎秀紀,大槻剛巳
    • Organizer
      第13回肺分子病態研究会
    • Place of Presentation
      ホテルレオパレス博多 (福岡)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590770
  • 1.  OTSUKI Takemi (40160551)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 148 results
  • 2.  NISHIMURA Yasumitsu (90360271)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 131 results
  • 3.  TAKEI Naoko (00509276)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  MATSUZAKI Hidenori (80335463)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 71 results
  • 5.  吉岡 大輔 (40638318)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 15 results
  • 6.  吉留 敬 (40304307)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 33 results
  • 7.  MAEDA Megumi (20434988)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  FUJIMOTO Wataru (50165429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 9.  HAYASHI Hiroaki (60388965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 10.  熊谷 直子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 109 results
  • 11.  今 重之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  井上 剛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  伊藤 達男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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