Yasukochi Tomoyo 安河内友世 (川久保友世)

… Alternative Names

川久保友世

安河内友世(川久保友世) ヤスコウチトモヨ

KAWAKUBO Tomoyo 川久保知世

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Researcher Number	70507813
Other IDs
Affiliation (Current)	2025: 九州大学, 歯学研究院, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 九州大学, 歯学研究院, 准教授 2022: 九州大学, 歯学研究科(研究院), 准教授 2018 – 2019: 福岡大学, 薬学部, 准教授 2014 – 2018: 福岡大学, 薬学部, 講師 2008 – 2012: 九州大学, 大学院・薬学研究院, 特任助教 2009 – 2010: 九州大学, 薬学研究院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 57010:Oral biological science-related / Functional basic dentistry Except Principal Investigator Functional basic dentistry / Basic Section 57010:Oral biological science-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 56040:Obstetrics and gynecology-related / Medium-sized Section 57:Oral science and related fields / Surgical dentistry / General surgery
Keywords	Principal Investigator DOHaD / エピゲノム / 口腔癌 / 肥満 / 栄養 / エネルギー代謝 / 生物学的実験 / 出生コホート / 扁平上皮 / エピジェネティクス … More / 癌 / 扁平上皮がん / 皮膚癌 / 葉酸 / 炎症 / 乳癌 / 口腔扁平上皮癌 / non-coding RNA / 浸潤 / がん / miRNA / エクソソーム / 生活習慣病 / GLP-1 / オステオカルシン / インクレチン / 腺分化 / 腺組織 / カテプシンE / 分化 / 悪性腫瘍 / プロテアーゼ … More Except Principal Investigator 肥満 / DOHaD / B細胞 / マクロファージ / T細胞サブセット / 疾患モデルマウス / IgG4関連疾患 / プロテアーゼ / 歯学 / 出生コホート / 生物学的実験 / エネルギー代謝 / 体重増加 / 骨量減少 / 閉経 / NF-κB / インスリン / 子宮内膜 / IGFBP-1 / 習慣流産 / PROK1 / 脱落膜 / インスリン抵抗性 / 不育症 / 病因 / IgG4疾患モデルマウス / IgG4産生B細胞 / TLR7 / T細胞 / DOHad / グリコーゲン分解 / 葉酸 / 生活習慣病 / one carbon metabolism / エピゲノム / グリコーゲンホスホリラーぜ / オステオカルシン / 生活習慣病胎児期起源説 / Toll 様受容体 / マクロファージサブセット / CCL16 / M2マクロファージ / 自然免疫 / モデルマウス / B細胞サブセット / Toll様受容体 / 濾胞性T細胞 / カテプシンE / 予後因子 / カテプシン E / 乳癌 / 薬学 / 細菌 / 酵素 / 感染症 / 蛋白質分子進化技術 / 早期診断キット / 分子標的治療薬 / ジンジパイン / 病原性プロテアーゼ / ジンジバリス菌 / 病原性細菌 / 歯周病 / 免疫学 / 癌 / 薬理学 / 発現制御 / トランスレーショナルリサーチ / 蛋白質 Less

胎内栄養環境が規定する成熟後の肥満・異所性脂肪蓄積の素因形成メカニズムPrincipal Investigator
- Principal Investigator
  
  安河内友世 (川久保友世)
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
女性ホルモン欠乏によるNF-κB活性化機構と骨・エネルギー代謝制御の解明
- Principal Investigator
  
  自見英治郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
Investigation on obesity predisposition and its patho-physiological properties regulated by transgenerational epigenomic regulation
- Principal Investigator
  
  平田雅人
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Fukuoka Dental College
出生コホート調査と生物学的実験の融合による肥満素因世代間継承メカニズムの証明Principal Investigator
- Principal Investigator
  
  安河内友世 (川久保友世 / 川久保友世)
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
Novel therapeutic strategies for the treatment of recurrent pregnancy loss by elucidating the function of endometrium and decidua with a focus on insulin response
- Principal Investigator
  
  後藤志信
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Nagoya City University
妊娠母体栄養が定義する肥満素因と肥満症多様性の経世代エピゲノム解析Principal Investigator
- Principal Investigator
  
  安河内友世 (川久保友世)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
Studies on the effect of maternal uncarboxylated osteocalcin on the metabolic properties of next generation
- Principal Investigator
  
  Hirata Masato
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Fukuoka Dental College
Immunologic specificity based pathogenesis of IgG4-related diseases and validation in mouse models of the disease
- Principal Investigator
  
  Nakamura Seiji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Kyushu University
Molecular mechanism for predisposition to develop oral cancer based on epigenome modification in uteroPrincipal Investigator
- Principal Investigator
  
  Kawakubo-Yasukochi Tomoyo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
Elucidation of mechanism on IgG4-related disease and establishment of disease model mouse
- Principal Investigator
  
  Nakamura Seiji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyushu University
Analysis of cancer pathogenesis regulated by tissue-specific non-coding RNAPrincipal Investigator
- Principal Investigator
  
  Kawakubo-Yasukochi Tomoyo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Fukuoka University
Homeostasis in glycoilipid metabolism-related organs maintained by incretinPrincipal Investigator
- Principal Investigator
  
  Yasukochi Tomoyo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Fukuoka University
Relationship between periodontal disease and systemic diseases: molecular mechanisms and novel therapy discovery
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
The role of cathepsin E in mammary carcinogenesis and prognosis in breast cancer
- Principal Investigator
  
  SUGIURA Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nagoya City University
唾液腺分化過程におけるカテプシンEの役割と唾液腺悪性腫瘍の新規診査技術の開発Principal Investigator
- Principal Investigator
  
  川久保友世
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
蛋白質高速分子進化技術による歯周病の分子標的治療薬及び早期診断キットの開発
- Principal Investigator
  
  山本健二
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Protease-mediated regulation of host immune system and application as therapeutic targets
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University

[Journal Article] Effects of Maternal Nutrition on Oral Health in Offspring2023
- Author(s)
  Kawakubo-Yasukochi Tomoyo、Hayashi Yoshikazu、Hirata Masato
- Journal Title
  
  Current Oral Health Reports
  
  Volume: 10 Issue: 3 Pages: 69-74
- DOI
  10.1007/s40496-023-00338-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0263, KAKENHI-PROJECT-22K09914, KAKENHI-PROJECT-20H03854
[Journal Article] Id4 modulates salivary gland homeostasis and its expression is downregulated in IgG4-related disease via miR-486-5p2023
- Author(s)
  1.Hayashi Y, Kimura S, Yano E, Yoshimoto S, Saeki A, Yasukochi A, Hatakeyama Y, Moriyama M, Nakamura S, Jimi E, Kawakubo-Yasukochi T.
- Journal Title
  
  Biochim Biophys Acta Mol Cell Res
  
  Volume: 1870(2) Issue: 2 Pages: 119404-119404
- DOI
  10.1016/j.bbamcr.2022.119404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09914, KAKENHI-PROJECT-22K10173, KAKENHI-PROJECT-22K19631, KAKENHI-PROJECT-22K17003, KAKENHI-PROJECT-20K17381, KAKENHI-PROJECT-22K18401, KAKENHI-PROJECT-19K22723, KAKENHI-PROJECT-23KK0164, KAKENHI-PROJECT-21K10075
[Journal Article] オステオカルシンのホルモン作用2022
- Author(s)
  溝上　顕子、安河内（川久保）友世、大谷　崇仁、平田　雅人
- Journal Title
  
  糖尿病・内分泌代謝科
  
  Volume: 54 Pages: 1-8
- Data Source
  KAKENHI-PROJECT-20H03854
[Journal Article] Adipocyte-specific GPRC6A ablation promotes diet-induced obesity by inhibiting lipolysis2021
- Author(s)
  Mukai Satoru、Mizokami Akiko、Otani Takahito、Sano Tomomi、Matsuda Miho、Chishaki Sakura、Gao Jing、Kawakubo-Yasukochi Tomoyo、Tang Ronghao、Kanematsu Takashi、Takeuchi Hiroshi、Jimi Eijiro、Hirata Masato
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100274-100274
- DOI
  10.1016/j.jbc.2021.100274
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-19K10054, KAKENHI-PROJECT-20K09890, KAKENHI-PROJECT-20K18512, KAKENHI-PROJECT-20H03854, KAKENHI-PROJECT-17K11645, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-18K17021, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-19K10052, KAKENHI-PROJECT-20K21681
[Journal Article] Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice2021
- Author(s)
  Kawakubo-Yasukochi Tomoyo、Yano Ena、Kimura Soi、Nishinakagawa Takuya、Mizokami Akiko、Hayashi Yoshikazu、Hatakeyama Yuji、Ohe Kenji、Yasukochi Atsushi、Nakamura Seiji、Jimi Eijiro、Hirata Masato
- Journal Title
  
  Molecular Metabolism
  
  Volume: 54 Pages: 101360-101360
- DOI
  10.1016/j.molmet.2021.101360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-19K10052, KAKENHI-PROJECT-19K10269, KAKENHI-PROJECT-20K23114, KAKENHI-PROJECT-20H03854
[Journal Article] Anthracenyl functionalization of half-sandwich carbene complexes: In vitro anticancer activity and reactions with biomolecules2021
- Author(s)
  Lee BYT, Sullivan MP, Yano E, Tong KKH, Hanif M, Kawakubo-Yasukochi T, Jamieson SMF, Soehnel T, Goldstone DC, Hartinger CG.
- Journal Title
  
  Inorg Chem
  
  Volume: 60(19) Issue: 19 Pages: 14636-14644
- DOI
  10.1021/acs.inorgchem.1c01675
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10052, KAKENHI-PROJECT-20K23114
[Journal Article] The roles of osteocalcin in lipid metabolism in adipose tissue and liver2020
- Author(s)
  Otani Takahito、Mizokami Akiko、Kawakubo-Yasukochi Tomoyo、Takeuchi Hiroshi、Inai Tetsuichiro、Hirata Masato
- Journal Title
  
  Advances in Biological Regulation
  
  Volume: 78 Pages: 100752-100752
- DOI
  10.1016/j.jbior.2020.100752
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-19K10052, KAKENHI-PROJECT-20H03854, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-18K17021
[Journal Article] GLP-1 signaling is required for improvement of glucose tolerance by osteocalcin. J. Endocrinol.2020
- Author(s)
  Mizokami, A., Mukai, S., Gao, J., Kawakubo-Yasukochi, T., Otani, T., Takeuchi, H., Jimi, E., Hirata, M.
- Journal Title
  
  Journal of Endocrinology
  
  Volume: 244 Issue: 2 Pages: 285-296
- DOI
  10.1530/joe-19-0288
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11649, KAKENHI-PROJECT-18K09510, KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-19K10052, KAKENHI-PROJECT-19K10054, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-18K17021, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-16K11479
[Journal Article] Maternal folic acid depletion during early pregnancy increases sensitivity to squamous tumor formation in the offspring in mice2019
- Author(s)
  Kawakubo-Yasukochi T, Morioka M, Ohe K, Yasukochi A, Ozaki Y, Hazekawa M, Nishinakagawa T, Ono K, Nakamura S, Nakashima M.
- Journal Title
  
  J Dev Orig Health Dis
  
  Volume: 10(6) Issue: 6 Pages: 683-691
- DOI
  10.1017/s2040174419000217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10052, KAKENHI-PROJECT-19K10269
[Journal Article] Glypican-3 gene silencing for ovarian cancer using siRNA-PLGA hybrid micelles in a murine peritoneal dissemination model2019
- Author(s)
  Hazekawa M, Nishinakagawa T, Kawakubo-Yasukochi T, Nakashima M.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 139(3) Issue: 3 Pages: 231-239
- DOI
  10.1016/j.jphs.2019.01.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10052
[Journal Article] Regulation of collagen type XVII expression by miR203a-3p in oral squamous cell carcinoma cells2019
- Author(s)
  Yasukochi A, Kawakubo-Yasukochi T, Morioka M, Hazekawa M, Nishinakagawa T, Ono K, Nakashima M, Nakamura S.
- Journal Title
  
  J Biochem
  
  Volume: in press Issue: 2 Pages: 163-173
- DOI
  10.1093/jb/mvz024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11496, KAKENHI-PROJECT-16K20585, KAKENHI-PROJECT-19K10052, KAKENHI-PROJECT-19K10269
[Journal Article] Maternal Folic Acid Depletion during Early Pregnancy Increases Sensitivity to Squamous Tumor Formation in the Offspring in Mice2019
- Author(s)
  Kawakubo-Yasukochi T, Morioka M, Ohe K, Yasukochi A, Ozaki Y, Hazekawa M, Nishinakagawa T, Ono K, Nakamura S, Nakashima M.
- Journal Title
  
  J Dev Orig Health Dis
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11496
[Journal Article] Evaluation of IC50 levels immediately after treatment with anticancer reagents using a real-time cell monitoring device2019
- Author(s)
  Hazekawa M, Nishinakagawa T, Kawakubo-Yasukochi T, Nakashima M.
- Journal Title
  
  Exp Ther Med
  
  Volume: 18(4) Pages: 3197-3205
- DOI
  10.3892/etm.2019.7876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10052
[Journal Article] <i>In Vitro</i> Anti-inflammatory Effects of the Phenylbutyric Acid Metabolite Phenylacetyl Glutamine2018
- Author(s)
  Hazekawa M, Ono K, Nishinakagawa T, Kawakubo-Yasukochi T, Nakashima M.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 6 Pages: 961-966
- DOI
  10.1248/bpb.b17-00799
- NAID
  130007382724
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2018-06-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11496
[Journal Article] miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment.2018
- Author(s)
  Kawakubo-Yasukochi T, Morioka M, Hazekawa M, Yasukochi A, Nishinakagawa T, Ono K, Kawano S, Nakamura S, Nakashima M.
- Journal Title
  
  Mol Carcinog
  
  Volume: 57 Issue: 2 Pages: 295-302
- DOI
  10.1002/mc.22744
- NAID
  120006900039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11496, KAKENHI-PROJECT-16K20585
[Journal Article] Assessment of cytotoxicity of imatinib for oral squamous cell carcinoma by real-time analysis system.2017
- Author(s)
  Hazekawa M, Morioka M, Nishinakagawa T, Kawakubo-Yasukochi T, Nakamura S, Nakashima M.
- Journal Title
  
  eJBio
  
  Volume: 13 Pages: 56-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11496
[Journal Article] Anti-inflammatory effects of water extract from bell pepper (Capsicum Annuum L. var. grossum) leaves in vitro.2017
- Author(s)
  Hazekawa M, Hideshima Y, Ono K, Nishinakagawa T, Kawakubo-Yasukochi T, Takatani-Nakase T, Nakashima M.
- Journal Title
  
  Ex Ther Med
  
  Volume: 14 Pages: 4349-4355
- DOI
  10.3892/etm.2017.5106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11496, KAKENHI-PROJECT-15K07955
[Journal Article] Uncarboxylated osteocalcin induces antitumor immunity against mouse melanoma cell growth.2017
- Author(s)
  Hayashi Y, Kawakubo-Yasukochi T, Mizokami A, Hazekawa M, Yakura T, Naito M, Takeuchi H, Nakamura S, Hirata M.
- Journal Title
  
  J Cancer
  
  Volume: 8 Issue: 13 Pages: 2478-2486
- DOI
  10.7150/jca.18648
- NAID
  120006900041
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11496, KAKENHI-PROJECT-17K11649, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-16K20421
[Journal Article] The SQUU-B cell line spread its metastatic properties to nonmetastatic clone SQUU-A from the same patient through exosomes2016
- Author(s)
  *Kawakubo-Yasukochi T, Morioka M, Hayashi Y, Nishinakagawa T, Hazekawa M, Kawano S, Nakamura S, Nakashima M.
- Journal Title
  
  J Oral Biosci
  
  Volume: 58 Pages: 33-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861554
[Journal Article] Exosomes from oral squamous carcinoma cell lines, SQUU-A and SQUU-B, define the tropism of lymphatic dissemination.2016
- Author(s)
  Morioka M, Kawakubo-Yasukochi T (corresponding author), Hayashi Y, Hazekawa M, Nishinakagawa T, Ono K, Kawano S, Nakamura S, Nakashima M.
- Journal Title
  
  J Oral Biosci
  
  Volume: 58 Issue: 4 Pages: 180-184
- DOI
  10.1016/j.job.2016.05.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K11496
[Journal Article] Long-term oral administration of osteocalcin induces insulin resistance in male mice fed a high-fat, high-sucrose diet2016
- Author(s)
  Yasutake Y., Mizokami A., Kawakubo-Yasukochi T., Chishaki S., Takahashi I., Takeuchi H., Hirata M.
- Journal Title
  
  Am. J. Physiol. Endocrinol. Metab.
  
  Volume: 310 Issue: 8 Pages: E662-E675
- DOI
  10.1152/ajpendo.00334.2015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861553, KAKENHI-PROJECT-26861554, KAKENHI-PROJECT-24229009, KAKENHI-PROJECT-16K11496
[Journal Article] Effect of collagen type I or human fibronectin on imatinib cytotoxicity in oral squamous cell carcinoma.2016
- Author(s)
  Morioka M, Hazekawa M, Kawakubo-Yasukochi T, Nishinakagawa T, Nakamura S, Nakashima M.
- Journal Title
  
  Pharmacology & Pharmacy
  
  Volume: 7 Issue: 07 Pages: 255-263
- DOI
  10.4236/pp.2016.77032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11496
[Journal Article] Differential roles of carboxylated and uncarboxylated osteocalcin in prostate cancer growth2016
- Author(s)
  Hayashi, Y., Kawakubo-Yasukochi, T., Mizokami, A., Takeuchi, H., Nakamura, S. and Hirata, M.
- Journal Title
  
  J. Cancer
  
  Volume: 7 Issue: 12 Pages: 1605-1609
- DOI
  10.7150/jca.15523
- NAID
  120006900040
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229009, KAKENHI-PROJECT-26861553, KAKENHI-PROJECT-16K11496, KAKENHI-PROJECT-16K20421
[Journal Article] Uncarboxylated osteocalcin increases serum nitric oxide levels and ameliorates hypercholesterolemia in mice fed an atherogenic diet.2016
- Author(s)
  Kondo A, Kawakubo-Yasukochi T (corresponding author), Mizokami A, Chishaki S, Takeuchi H, Hirata M.
- Journal Title
  
  eJBio
  
  Volume: 13 Pages: 22-28
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K11496
[Journal Article] The SQUU-B cell line spreads its metastatic properties to nonmetastatic clone SQUU-A from the same patient through exosomes.2016
- Author(s)
  Kawakubo-Yasukochi T (corresponding author), Morioka M, Hayashi Y, Nishinakagawa T, Hazekawa M, Kawano S, Nakamura S, Nakashima M.
- Journal Title
  
  J Oral Biosci
  
  Volume: 58 Issue: 1 Pages: 33-38
- DOI
  10.1016/j.job.2015.10.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K11496
[Journal Article] Maternal oral administration of osteocalcin protects offspring from metabolic impairment in adulthood2016
- Author(s)
  *Kawakubo-Yasukochi T, Kondo A, Mizokami A, Hayashi Y, Chishaki S, Nakamura S, Takeuchi H, Hirata M.
- Journal Title
  
  Obesity
  
  Volume: 24 Issue: 4 Pages: 895-907
- DOI
  10.1002/oby.21447
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861554, KAKENHI-PROJECT-24229009, KAKENHI-PROJECT-16K11496
[Journal Article] Promotion of insulin-induced glucose uptake in C2C12 myotubes by osteocalcin.2015
- Author(s)
  Tsuka, S., Aonuma, F., Higashi, S., Ohsumi, T., Nagano, K., Mizokami, A., Kawakubo-Yasukochi, T., Masaki, C., Hosokawa, R. and Hirata, M. and Takeuchi, H.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 459 Issue: 3 Pages: 437-442
- DOI
  10.1016/j.bbrc.2015.02.123
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592805, KAKENHI-PROJECT-26861553, KAKENHI-PROJECT-15K20374, KAKENHI-PROJECT-24229009, KAKENHI-PROJECT-26861554
[Journal Article] Organ network for preventing metabolic syndromes with a reference to the roles of osteocalcin2015
- Author(s)
  溝上顕子、*川久保(安河内)友世、竹内弘、平田雅人
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 145 Issue: 4 Pages: 201-205
- DOI
  10.1254/fpj.145.201
- NAID
  130005061556
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861554, KAKENHI-PROJECT-26861553, KAKENHI-PROJECT-24229009
[Journal Article] A Novel, Potent Dual Inhibitor of Arg-gingipains and Lys-gingipain as a Promising Agent for Periodontal Disease Therapy2014
- Author(s)
  Kataoka S., Baba A., Suda Y., Takii R., Hashimoto M., *Kawakubo T., Asao T., Kadowaki T., and Yamamoto K.
- Journal Title
  
  The FASEB J
  
  Volume: 28 Issue: 8 Pages: 3564-3578
- DOI
  10.1096/fj.14-252130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861554
[Journal Article] Oral administration of osteocalcin improves glucose utilization by stimulating glucagon-like peptide-1 secretion.2014
- Author(s)
  Mizokami, A., Yasutake, Y., Higashi, S., Kawakubo-Yasukochi, T., Chishaki, S., Takahashi, I., Takeuchi, H. and Hirata, M.
- Journal Title
  
  Bone
  
  Volume: 69 Pages: 68-79
- DOI
  10.1016/j.bone.2014.09.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592805, KAKENHI-PROJECT-26861553, KAKENHI-PROJECT-26861554, KAKENHI-PROJECT-24229009
[Journal Article] Role of cathepsin E in decidual macrophage of patients with recurrent miscarriage.2014
- Author(s)
  Goto S, Ozaki Y, Suzumori N, Yasukochi A, Kawakubo T, Furuno T, Nakanishi M, Yamamoto K, Sugiura-Ogasawara M.
- Journal Title
  
  Mol Hum Reprod.
  
  Volume: 20 Issue: 5 Pages: 454-462
- DOI
  10.1093/molehr/gau008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592478, KAKENHI-PROJECT-24592479, KAKENHI-PROJECT-26861554, KAKENHI-PROJECT-26861762
[Journal Article] Cathepsin E in mammary gland: Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer.2013
- Author(s)
  Tomoyo Kawakubo, Atsushi Yasukochi, Tatsuya Toyama, Satoru Takahashi, Kuniaki Okamoto, Takayuki Tsukuba, Seiji Nakamura, Yasuhiko Ozaki, Koichi Nishigaki, Hiroko Yamashita, and Kenji Yamamoto
- Journal Title
  
  Carcinogenesis
  
  Volume: 00 Issue: 3 Pages: 1-13
- DOI
  10.1093/carcin/bgt373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24240059, KAKENHI-PROJECT-24592479, KAKENHI-PROJECT-24659840, KAKENHI-PROJECT-25293383, KAKENHI-PROJECT-25462920, KAKENHI-PROJECT-26670906, KAKENHI-PROJECT-26861554, KAKENHI-PROJECT-26861762
[Journal Article] Emerging roles of cathepsin E in host defense mechanisms2012
- Author(s)
  Yamamoto K, Kawakubo T, Yasukochi A, Tsukuba T
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1824 Pages: 105-112
- NAID
  120005324431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Emerging roles of cathepsin E in host defense mechanisms2012
- Author(s)
  Yamamoto, K., et al
- Journal Title
  
  Biochim.Biophys.Acta.
  
  Volume: 1824 Issue: 1 Pages: 105-112
- DOI
  10.1016/j.bbapap.2011.05.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791790, KAKENHI-PROJECT-22390350
[Journal Article] Role of the transcription factor Sp1 in regulating the expression of the murine cathepsin E gene2012
- Author(s)
  Okamoto K, Okamoto Y, Kawakubo T, Iwata J, Yasuda Y, Tsukuba T, Yamamoto K
- Journal Title
  
  J Biochem.
  
  Volume: 151 Pages: 263-272
- NAID
  10031166065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Role of the transcription factor Sp1 in regulating the expression of the murine cathepsin E gene2012
- Author(s)
  Okamoto K, Okamoto Y, Kawakubo T, Iwata J, Yasuda Y, Tsukuba T, Yamamoto K
- Journal Title
  
  J Biochem
  
  Volume: 151(3) Pages: 263-272
- NAID
  10031166065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E as a potent anticancer protease.2011
- Author(s)
  Kawakubo T, Yasukochi A, Nakamura S, Yamamoto K.
- Journal Title
  
  J.Oral Biosci.
  
  Volume: 53(印刷中)
- NAID
  10028222723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E as a potent anticancer protease.2011
- Author(s)
  Kawakubo, T., et al.
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: (In press)
- NAID
  10028222723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791790
[Journal Article] Cathepsin E as a Potent Anticancer Protease2011
- Author(s)
  Kawakubo, T., et al
- Journal Title
  
  J. Oral Biosci.
  
  Volume: 53 Issue: 2 Pages: 128-136
- DOI
  10.2330/joralbiosci.53.128
- NAID
  10028222723
- ISSN
  1349-0079, 1880-3865
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791790
[Journal Article] Emerging roles of cathepsin E in host defense mechanisms2011
- Author(s)
  Yamamoto K, Kawakubo T, Yasukochi A, Tsukuba T.
- Journal Title
  
  Biochim.Biophys.Acta
  
  Volume: (印刷中)
- NAID
  120005324431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] The role of cathepsin E in terminal differentiation of keratinocytes2011
- Author(s)
  Kawakubo T, Yasukochi A, Okamoto K, Okamoto Y, Nakamura S, Yamamoto K
- Journal Title
  
  Biol. Chem
  
  Volume: 392 Pages: 571-583
- NAID
  120005007885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E as a potent anticancer protease2011
- Author(s)
  Kawakubo T, Yasukochi A, Nakamura S, Yamamoto K
- Journal Title
  
  J. Oral Biosci
  
  Volume: 53 (2) Pages: 126-136
- NAID
  10028222723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E as a potent anticancer protease2011
- Author(s)
  Kawakubo T, Yasukochi A, Nakamura S, Yamamoto K
- Journal Title
  
  J.Oral Biosci.
  
  Volume: 53 Pages: 126-136
- NAID
  10028222723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Peptide aptamer-based ELISA-like system for detection of cathepsin E in tissues and plasma2011
- Author(s)
  Kitamura K, Biyani M, Futakami M, Ueno-Tsuji S, Suzuki M, Kawakubo T, Yamamoto K, Nishigaki K
- Journal Title
  
  J.Mol.Biomark.Diagn.
  
  Volume: 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] The role of cathepsin E in terminal differentiation of keratinocytes2011
- Author(s)
  Kawakubo T
- Journal Title
  
  Biol.Chem.
  
  Volume: 392 Issue: 6 Pages: 571-585
- DOI
  10.1515/bc.2011.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592369, KAKENHI-PROJECT-22791790, KAKENHI-PROJECT-22390350
[Journal Article] The role of cathepsin E in terminal differentiation of keratinocytes.2011
- Author(s)
  Kawakubo, T., et al.
- Journal Title
  
  Biological Chemistry
  
  Volume: (In press)
- NAID
  120005007885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791790
[Journal Article] Peptide aptamer-based ELISA-like system for detection of cathepsin E in tissues and plasma2011
- Author(s)
  Kitamura, K., et al
- Journal Title
  
  Mol.Biomark.Diagn.
  
  Volume: 2 Issue: 01 Pages: 104-104
- DOI
  10.4172/2155-9929.1000104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791790, KAKENHI-PROJECT-22390350
[Journal Article] In vitro selection of cathepsin E-activity-enhancing peptide aptamers at neutral pH2011
- Author(s)
  Biyani M, Futakami M, Kitamura K, Kawakubo T, Suzuki M, Yamamoto K, Nishigaki K
- Journal Title
  
  Int. J. Pep
  
  Volume: 2011 Pages: 1-8
- DOI
  10.1155/2011/834525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] In vitro selection of cathepsin E-activity-enhancing peptide aptamers at neutral pH2011
- Author(s)
  Biyani M, Futakami M, Kitamura K, Kawakubo T, et al
- Journal Title
  
  Int.J.Pep.
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostate cancer cells showing resistance to TRAIL-mediated apoptosis.2010
- Author(s)
  Yasukochi A, Kawakubo T, Nakamura S, Yamamoto K.
- Journal Title
  
  Biol Chem (in press)
- NAID
  120006900038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostate cancer cells showing resistance to TRAIL-mediated apoptosis2010
- Author(s)
  Yasukouchi A, Kawakubo T, Nakamura S, Yamamoto K
- Journal Title
  
  Biol. Chem
  
  Volume: 391 Pages: 947-958
- NAID
  120006900038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostate cancer cells showing resistance to TRAIL-mediated apoptosis2010
- Author(s)
  Yasukochi, A., et al.,
- Journal Title
  
  Biol Chem (In press)
- NAID
  120006900038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostatecancer cells showing resistance to TRAIL-mediated apoptosis2010
- Author(s)
  Yasukochi A, Kawakubo T, Nakamura S, Yamamoto K
- Journal Title
  
  Biol.Chem.
  
  Volume: 391 Pages: 947-958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390350
[Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostate cancer cells showing resistance to TRAIL-mediated apoptosis.2010
- Author(s)
  Yasukochi, A., et al.
- Journal Title
  
  Biological Chemistry
  
  Volume: 391 Pages: 947-958
- NAID
  120006900038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791790
[Journal Article] Development of systemin in vitro evolution and its application to generation of peptide aptamer-based inhibitors of cathepsin E.2009
- Author(s)
  Kitamura K, Yoshida C, Kinoshita Y, Kadowaki T, Takahashi Y, Tayama T, Kawakubo T, Naimuddin M, Salimulla M, Nemoto N, Hanada K, Husimi Y, Yamamoto K, Nishigaki K.
- Journal Title
  
  J. Mol. Biol. 387
  
  Pages: 1186-1198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Gene expression of profiling of mammary glands of cathepsin E-deficient mice compared with wild-type littermates.2008
- Author(s)
  Kawakubo T., Yasukochi A., Tsukuba T., Kadowaki T., Yamamoto K.
- Journal Title
  
  Biochimie 90
  
  Pages: 396-404
- NAID
  120006900027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Gene expression of profiling of mammary glands of cathepsin E-deficientmice compared with wild-type littermates2008
- Author(s)
  Kawakubo T, et al.
- Journal Title
  
  Biochimie 90
  
  Pages: 396-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Cathepsin E Prevents Tumor Growth and Metastasis by Catalyzing the Proteolytic Release of Soluble TRAIL from Tumor Cell2007
- Author(s)
  Kawakubo T., Okamoto K., Iwata J., Shin M., Okamoto Y., Yasukochi A., Nakayama K.I., Kadowaki T., Tsukuba T., Yamamoto K.
- Journal Title
  
  Surface. Cancer Res. 67
  
  Pages: 10869-10878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Cathepsin E Prevents Tumor Growth and Metastasis by Catalyzing the Proteohnic Release of Soluble TRAIL from Tumor Cell Surface.2007
- Author(s)
  Kawakubo, T., et. al.
- Journal Title
  
  Cancer Research 67
  
  Pages: 10869-10878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromonas gingicalis-infected cells.2007
- Author(s)
  Kadowaki, T., Takii, R., Yamatake, K., Kawakubo, T., Tsukuba, T., Yamamoto, K.
- Journal Title
  
  Frontiers in Biosci. 12
  
  Pages: 4800-4809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses.2007
- Author(s)
  Shin, M., Kadowaki, T., Iwata, J., Kawakubo, T., Yamaguchi, N., Takii, R., Tsukuba, T., Yamamoto, K.
- Journal Title
  
  Biol. Chem. 388
  
  Pages: 1173-1181
- NAID
  120006900037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Patent] 新規ペプチド及びその使用2010
- Inventor(s)
  西垣功一、北村幸一郎、Madhu Biyani、二上雅恵、山本健二、川久保友世、安河内篤
- Industrial Property Rights Holder
  西垣功一、北村幸一郎、Madhu Biyani、二上雅恵、山本健二、川久保友世、安河内篤
- Industrial Property Number
  2009-245763
- Filing Date
  2010-03-17
- Acquisition Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-19209058
[Patent] アンチエイジング剤2009
- Inventor(s)
  山本健二、川久保友世、安河内篤
- Industrial Property Rights Holder
  山本健二、川久保友世、安河内篤
- Industrial Property Number
  2009-264894
- Filing Date
  2009-11-20
- Acquisition Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-19209058
[Patent] 新規な抗癌カテプシン製剤およびそれを用いた癌併用療法抗癌剤2007
- Inventor(s)
  山本健二、川久保友世、安河内篤
- Industrial Property Rights Holder
  山本健二、川久保友世、安河内篤
- Industrial Property Number
  2008-500586
- Filing Date
  2007-02-19
- Acquisition Date
  2007-02-19
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Pathophysiological role of Id4 for salivary gland homeostasis and IgG4-related diseases2024
- Author(s)
  Yoshikazu Hayashi, Soi Kimura, Ena Yano, Shohei Yoshimoto, Ayaka Saeki, Teppei Yasukuni, Atsushi Yasukochi, Yuji Hatakeyama, Masato Hirata, Eijiro Jimi, Tomoyo Kawakubo-Yasukochi
- Organizer
  8th Edition of International Conference on Dentistry and Oral Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0263
[Presentation] Pathophysiological role of Id4 for salivary gland homeostasis and IgG4-related diseases2024
- Author(s)
  Yoshikazu Hayashi, Soi Kimura, Ena Yano, Shohei Yoshimoto, Ayaka Saeki, Teppei Yasukuni, Atsushi Yasukochi, Yuji Hatakeyama, Masato Hirata, Eijiro Jimi, Tomoyo Kawakubo-Yasukochi
- Organizer
  8th Edition of International Conference on Dentistry and Oral Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] The role of Id4 on energy metabolism in adipose tissue and liver2023
- Author(s)
  Zhu R, Hayashi Y, Kimura S, Hatakeyama Y, Hirata M, Jimi E, Kawakubo-Yasukochi T.
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22KK0263
[Presentation] がん細胞増殖におけるイタコン酸の役割2023
- Author(s)
  佐伯彩華、林慶和、吉本尚平、畠山雄次、平田雅人、自見英治郎、安河内(川久保)友世
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22KK0263
[Presentation] 創薬ターゲットとしての生体内分子ーオステオカルシンとイタコン酸ー2023
- Author(s)
  安河内（川久保）友世
- Organizer
  北九州化学工学懇話会（KACE）第76回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] がん細胞増殖におけるイタコン酸の役割2023
- Author(s)
  佐伯彩華、林慶和、吉本尚平、畠山雄次、平田雅人、自見英治郎、安河内（川久保）友世
- Organizer
  第96回日本生化学会
- Data Source
  KAKENHI-PROJECT-20H03854
[Presentation] イタコン酸によるがん細胞抗酸化システムの制御2023
- Author(s)
  佐伯彩華、林慶和、吉本尚平、畠山雄次、平田雅人、自見英治郎、安河内(川久保)友世
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22KK0263
[Presentation] Regulation of hepatic fatty acid metabolism by Id42023
- Author(s)
  Zhu R, Hayashi Y, Kimura S, Yano E, Hatakeyama Y, Hirata M, Jimi E, Lo YC, Kawakubo-Yasukochi T.
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] 九州大学歯学部・大学院歯学研究院における国際推進の取り組み2023
- Author(s)
  安河内(川久保)友世、自見英治郎
- Organizer
  日本歯科保健医療国際協力学会歯科医学系国際協力教育促進ワークショップ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0263
[Presentation] 閉経後の骨・エネルギー代謝異常の進展を制御する環境エンリッチメント2023
- Author(s)
  鞠超然、安河内(川久保)友世、高田、小倉綾乃、川端由子、自見英治郎
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22KK0263
[Presentation] 唾液腺恒常性維持におけるId4の役割と唾液腺疾患への関与2023
- Author(s)
  林慶和、木村宗惟、吉本尚平、矢野恵奈、自見英治郎、安河内（川久保）友世
- Organizer
  第128回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] 創薬ターゲットとしての生体内分子ーオステオカルシンとイタコン酸ー2023
- Author(s)
  安河内(川久保)友世
- Organizer
  北九州化学工学懇話会(KACE)第76回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-22KK0263
[Presentation] The role of Id4 on energy metabolism in adipose tissue and liver2023
- Author(s)
  Rongzhong Zhu, Yoshikazu Hayashi, Soi Kimura, Yuji Hatakeyama , Masato Hirata, Eijiro Jimi, Tomoyo Kawakubo-Yasukochi
- Organizer
  第65回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-20H03854
[Presentation] Regulation of hepatic fatty acid metabolism by Id42023
- Author(s)
  Zhu R, Hayashi Y, Kimura S, Yano E, Hatakeyama Y, Hirata M, Jimi E, Lo YC, Kawakubo-Yasukochi T.
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22KK0263
[Presentation] 生活環境に起因する閉経後の骨粗鬆症やエネルギー代謝異常症の進展制御機構2023
- Author(s)
  鞠超然、安河内（川久保）友世、高田、小倉綾乃、川端由子、自見英治郎
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] イタコン酸によるがん細胞抗酸化システムの制御2023
- Author(s)
  佐伯彩華、林慶和、吉本尚平、畠山雄次、平田雅人、自見英治郎、安河内（川久保）友世
- Organizer
  第65回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-20H03854
[Presentation] The role of Id4 on energy metabolism in adipose tissue and liver2023
- Author(s)
  Zhu R, Hayashi Y, Kimura S, Hatakeyama Y, Hirata M, Jimi E, Kawakubo-Yasukochi T.
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] 生活環境に起因する閉経後の骨粗鬆症やエネルギー代謝異常症の進展制御機構2023
- Author(s)
  鞠超然、安河内(川久保)友世、高田、小倉綾乃、川端由子、自見英治郎
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22KK0263
[Presentation] Regulation of hepatic fatty acid metabolism by Id42023
- Author(s)
  Rongzhong Zhu, Yoshikazu Hayashi, Soi Kimura, Ena Yano, Yuji Hatakeyama, Masato Hirata, Eijiro Jimi, Lo Yi-Chen, Tomoyo Kawakubo-Yasukochi
- Organizer
  第96回日本生化学会
- Data Source
  KAKENHI-PROJECT-20H03854
[Presentation] イタコン酸によるがん細胞抗酸化システムの制御2023
- Author(s)
  佐伯彩華、林慶和、吉本尚平、畠山雄次、平田雅人、自見英治郎、安河内（川久保）友世
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] 九州大学歯学部・大学院歯学研究院における国際推進の取り組み2023
- Author(s)
  安河内（川久保）友世、自見英治郎
- Organizer
  日本歯科保健医療国際協力学会歯科医学系国際協力教育促進ワークショップ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] 閉経後の骨・エネルギー代謝異常の進展を制御する環境エンリッチメント2023
- Author(s)
  鞠超然、安河内（川久保）友世、高田、小倉綾乃、川端由子、自見英治郎
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] がん細胞増殖におけるイタコン酸の役割2023
- Author(s)
  佐伯彩華、林慶和、吉本尚平、畠山雄次、平田雅人、自見英治郎、安河内（川久保）友世
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] The role of Id4 in salivary gland and its involvement in the pathology of IgG4-related disease2022
- Author(s)
  Kimura S, Hayashi Y, Yano E, Saeki A, Yasukochi A, Moriyama M, Nakamura S, Jimi E, Kawakubo-Yasukochi T.
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] 唾液腺におけるId4の役割と病態への関与2022
- Author(s)
  木村宗惟、林慶和、佐伯彩華、安河内篤、中村誠司、自見英治郎、安河内（川久保）友世
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] 妊娠母体栄養がもたらす産仔の肝グリコーゲン分解異常とオステオカルシンによる回避2022
- Author(s)
  安河内（川久保）友世、矢野恵奈、木村宗惟、溝上顕子、林慶和、安河内篤、中村誠司、自見英治郎、平田雅人
- Organizer
  第9回日本DOHaD学会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] がん進展におけるイタコン酸の役割2022
- Author(s)
  佐伯彩華、林慶和、自見英治郎、安河内（川久保）友世
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] Maternal high calorie diet during pregnancy induces abnormal hepatic glycogenolysis in the offspring and it is mitigated by osteocalcin2022
- Author(s)
  Kawakubo-Yasukochi T, Yano E, Kimura S, Mizokami A, Hayashi Y, Yasukochi A, Nakamura S, Jimi E, Hirata M.
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] 妊娠母体の高カロリー食摂取による産仔の肝グリコーゲン分解異常とオステオカルシンによる改善機構の解析2022
- Author(s)
  安河内（川久保）友世、矢野恵奈、木村宗維、溝上顕子、林　慶和、安河内篤、中村誠司、自見英治郎、平田雅人
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03854
[Presentation] 妊娠母体栄養がもたらす産仔の肝グリコーゲン分解異常とオステオカルシンによる回避2022
- Author(s)
  安河内（川久保）友世、矢野恵奈、木村宗維、溝上顕子、林　慶和、安河内篤、中村誠司、自見英治郎、平田雅人
- Organizer
  第9回日本DOHaD学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03854
[Presentation] Physiological and Pathological Roles of Inhibitor of Differentiation 4 in the Salivary Gland2022
- Author(s)
  Kimura S, Kawakubo-Yasukochi T, Hayashi Y, Yano E, Moriyama M, Nakamura S, Jimi E.
- Organizer
  The 5th KOB OBT joint international symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09914
[Presentation] 妊娠母体の高カロリー食摂取による産仔の肝グリコーゲン分解異常とオステオカルシンによる改善機構の解析2021
- Author(s)
  安河内（川久保）友世、矢野恵奈、木村宗維、溝上顕子、林　慶和、安河内篤、中村誠司、自見英治郎、平田雅人
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03854
[Presentation] Distinctive non-cording RNA profile in the serum of IgG4-related disease patient2021
- Author(s)
  Kimura S, Kawakubo-Yasukochi T, Hayashi Y, Yano E, Moriyama M, Nakamura S, Jimi E.
- Organizer
  The 23rd Korea-Japan Joint Seminar on Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] Association of maternal folic acid shortage during early pregnancy with carcinogenic risk in the offspring2021
- Author(s)
  Kawakubo-Yasukochi T, Yano E, Kimura S, Nakamura S, Jimi E.
- Organizer
  The 23rd Korea-Japan Joint Seminar on Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] Physiological and Pathological Roles of Inhibitor of Differentiation 4 in the Salivary Gland2021
- Author(s)
  Kimura S, Kawakubo-Yasukochi T, Hayashi Y, Yano E, Moriyama M, Nakamura S, Jimi E.
- Organizer
  KOB & OBT 5th Joint International Symposium 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] 脂肪細胞表面受容体GPRC6Aの食事誘発性肥満における役割2020
- Author(s)
  溝上顕子, 大谷崇仁, 松田美穂、安河内（川久保）友世、竹内弘, 自見英治郎, 平田　雅人
- Organizer
  第62回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] 口腔扁平上皮癌におけるBP180の発現制御機構2020
- Author(s)
  安河内篤、安河内（川久保）友世、中村誠司
- Organizer
  第62回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] 胎内栄養環境に基づく糖脂質代謝制御とオステオカルシンの関与2020
- Author(s)
  安河内（川久保）友世、溝上顕子、木村宗惟、中村誠司、自見英治郎、平田雅人
- Organizer
  第62回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] IgG4関連疾患病態形成における非コードRNAの役割2020
- Author(s)
  木村宗惟、安河内（川久保）友世、中村誠司、自見英治郎
- Organizer
  第62回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] The effect of maternal uncarboxylated osteocalcin on the metabolic properties of next generation2019
- Author(s)
  Kawakubo-Yasukochi T, Kondo A, Mizokami A, Hirata M
- Organizer
  The 11th DOHaD World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] miR-200c-3pによる口腔扁平上皮癌の浸潤制御機構2019
- Author(s)
  安河内（川久保）友世、森岡政彦、櫨川舞、西中川拓也、安河内篤、中村誠司、中島学
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] 妊娠母体の葉酸不足は仔の皮膚および舌において扁平上皮の発癌感受性を増強させる2019
- Author(s)
  安河内（川久保）友世、森岡政彦、安河内篤、櫨川舞、西中川拓也、中村誠司、中島学
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment2019
- Author(s)
  Kawakubo-Yasukochi T, Morioka M, Hazekawa M, Nishinakagawa T, Yasukochi A, Nakamura S, Nakashima M.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] The effect of maternal folic acid deficiency during early pregnancy on the carcinogen sensitivity of offspring in mice2019
- Author(s)
  Kawakubo-Yasukochi T, Morioka M, Atsushi Yasukochi, Hazekawa M, Nishinakagawa T, Ono K, Nakamura S, Nakashima M
- Organizer
  The 11th DOHaD World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10052
[Presentation] 妊娠母体が飲用する胎盤通過性オステオカルシンが胎児の糖脂質代謝関連臓器のエピジェネティックな変化に及ぼす影響2018
- Author(s)
  安河内（川久保）友世
- Organizer
  DIJFカンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] 抗炎症作用を有するピーマン葉水抽出エキス中の成分探索2018
- Author(s)
  櫨川舞、小野和彦、西中川拓也、安河内（川久保）友世、中島学
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] PBA投与後血清中に誘導される抗炎症活性本体の解明2018
- Author(s)
  小野和彦、櫨川舞、西中川拓也、安河内（川久保）友世、中島学
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Microenvironmental communications within oral squamous cell carcinoma defined by exosomes2017
- Author(s)
  Morioka M, Kawakubo-Yasukochi T, Hazekawa M, Nishinakagawa T, Ono K, Kawano S, Nakamura S, Nakashima M.
- Organizer
  第65回国際歯科研究学会日本部会総会・学術大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Exosomes from oral squamous carcinoma cells define the tropism of invasiveness and lymphatic dissemination2017
- Author(s)
  Morioka M, Kawakubo-Yasukochi T, Nakamura S, Nakashima M.
- Organizer
  Kyudai Oral Bioscience
- Place of Presentation
  Fukuoka, JAPAN
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] 非コードRNAによる口腔癌の進展制御2017
- Author(s)
  川久保-安河内友世、森岡政彦、安河内篤、中村誠司、中島学
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] 卵巣がんにおけるsiRNA-PLGAハイブリッドミセル製剤の遺伝子抑制による治療効果2017
- Author(s)
  櫨川舞、西中川拓也、安河内友世、中島学
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Exosome-mediated crosstalk determines invasiveness and organotropic metastasis in oral squamous cell carcinoma2017
- Author(s)
  Morioka M, Kawakubo-Yasukochi T, Hazekawa M, Nishinakagawa T, Ono K, Kawano S, Nakamura S, Nakashima M.
- Organizer
  The 5th ASHNO Congress 2017, Congress of Asian Society of Head and Neck Oncology
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2017-03-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] PBA投与による血中マウスDSS誘発性IBD発症抑制性物質の探索2017
- Author(s)
  小野和彦、櫨川舞、西中川拓也、安河内（川久保）友世、中島学
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Uncarboxylated osteocalcin prevents cancer progression through multiple mechanisms including immune system2017
- Author(s)
  Hayashi Y, Kawakubo-Yasukochi T, Mizokami A, Nakamura S, Hirata M.
- Organizer
  Kyudai Oral Bioscience
- Place of Presentation
  Fukuoka, JAPAN
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] PBA代謝物PAGlnの抗炎症作用に関するin vitro評価2017
- Author(s)
  櫨川舞、小野和彦、西中川拓也、安河内友世、中島学
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] 口腔扁平上皮癌におけるBP180の局在2017
- Author(s)
  安河内篤、森岡政彦、川久保-安河内友世、中島学、中村誠司
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] 口腔扁平上皮癌におけるAT1受容体拮抗薬の影響2017
- Author(s)
  森岡政彦、川久保-安河内友世、中村誠司、中島学
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] The significance of BP180 expression in oral squamous carcinoma cell invasion2017
- Author(s)
  Yasukochi A, Morioka M, Kawakubo-Yasukochi T, Nakashima M, Nakamura S.
- Organizer
  The 5th ASHNO Congress 2017, Congress of Asian Society of Head and Neck Oncology
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2017-03-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Preparation of self-assembled siRNA-PLGA hybrid conjugate micelles as GPC-3 gene silencing therapy for ovarian cancer2017
- Author(s)
  Hazekawa M, Morioka M, Nishinakagawa T, Kawakubo-Yasukochi T, Nakamura S, Nakashima M
- Organizer
  The 6th Pharmaceutical Sciences World Congress 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] 口腔扁平上皮癌細胞由来エクソソームによるがん微小環境制御とリンパ行性転移の規定2017
- Author(s)
  森岡政彦、安河内（川久保）友世、中村誠司
- Organizer
  第71回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] 妊娠母体が摂取したオステオカルシンが次世代に及ぼす影響2017
- Author(s)
  川久保-安河内友世、近藤皓彦、溝上顕子、平田雅人
- Organizer
  第6回日本DOHaD学会学術集会
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Therapeutic effects of self-assembled siRNA-PLGA hybrid conjugate micelles for ovarian cancer2017
- Author(s)
  Hazekawa M, Morioka M, Nishinakagawa T, Kawakubo-Yasukochi T, Nakamura S, Nakashima M.
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Application of real-time cell monitoring device in evaluation the IC50 levels of anticancer reagents2016
- Author(s)
  Hazekawa M, Morioka M, Nishinakagawa T, Yasukochi T, Nakashima M.
- Organizer
  第75回日本癌学会学術大会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] 口腔扁平上皮癌細胞由来エクソソームによる細胞間クロストークと病態形成2016
- Author(s)
  森岡政彦、川久保-安河内友世、中村誠司
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Intercelluler crosstalk defined by exosomes from oral squamous carcinoma cells determines its pathological process2016
- Author(s)
  Morioka M, Kawakubo-Yasukochi T, Hazekawa M, Nishinakagawa T, Ono K, Kawano S, Nakamura S, Nakashima M.
- Organizer
  Australian and New Zealand Head & neck cancer society
- Place of Presentation
  Auckland, New Zealand
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] The role of uncarboxylated osteocalcin in prevention of early atherosclerosis2016
- Author(s)
  Kondo A, Kawakubo-Yasukochi T, Mizokami A, Takeuchi H, Hirata M.
- Organizer
  The 9th Korea-Japan conference on cellular signaling for young scientists
- Place of Presentation
  Seol, Korea
- Year and Date
  2016-07-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] The effect of uncarboxylated osteocalcin on cancer growth2016
- Author(s)
  Hayashi Y, Kawakubo-Yasukochi T, Mizokami A, Nakamura S, Takeuchi H, Hirata M.
- Organizer
  The 9th Korea-Japan conference on cellular signaling for young scientists
- Place of Presentation
  Seol, Korea
- Year and Date
  2016-07-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] オステオカルシンを用いた次世代生活習慣病改善へのアプローチ2016
- Author(s)
  安河内（川久保）友世、近藤皓彦、溝上顕子、竹内弘、平田雅人
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京
- Year and Date
  2016-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] 癌の増殖における非(低)カルボキシル化オステオカルシンの機能2016
- Author(s)
  林慶和、川久保-安河内友世、溝上顕子、中村誠司、竹内弘、平田雅人
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Identify of the cytotoxic factor secreted by tumor cell line2016
- Author(s)
  Nishinakagawa T, Hazekawa M, Yasukochi T, Nakashima M.
- Organizer
  第75回日本癌学会学術大会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Assessment of cytotoxicity of anticancer reagents for oral squamous cell carcinomas using a real-time cell monitoring analysis system2016
- Author(s)
  Hazekawa M, Morioka M, Nishinakagawa T, Yasukochi T, Nakashima M.
- Organizer
  Australian and New Zealand Head & neck cancer society
- Place of Presentation
  Auckland, New Zealand
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Link of BP180 bullous pemphigoid autoantigen to invasion of oral squamous carcinoma cell2016
- Author(s)
  Yasukochi A, Morioka M, Kawakubo-Yasukochi T, Obayashi K, Nakashima M, Nakamura S.
- Organizer
  Australian and New Zealand Head & neck cancer society
- Place of Presentation
  Auckland, New Zealand
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] New functions of osteocalcin in cancer progression2016
- Author(s)
  Hayashi Y, Kawakubo-Yasukochi T, Nakamura S, Hirata M.
- Organizer
  The 57th Congress of the Korean Association of Oral Maxillofacial Surgeons
- Place of Presentation
  Gunsan, Korea
- Year and Date
  2016-04-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11496
[Presentation] Prevention of early atherosclerosis with uncarboxylated osteocalcin2016
- Author(s)
  Kondo A, *Kawakubo-Yasukochi T, Mizokami A, Takeuchi H, Hirata M.
- Organizer
  The 13th Asia Pacific Federation of Pharmacologist (APFP) Meeting
- Place of Presentation
  Bankok, Thailand
- Year and Date
  2016-02-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] Transmission of invasive potential between oral squamous carcinoma cells from the same patient by the exosomes2015
- Author(s)
  *Yasukochi T, Morioka M, Nishinakagawa T, Hazekawa M, Nakamura S, Nakashima M.
- Organizer
  The 74th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] 前立腺癌におけるオステオカルシンの位置付け2015
- Author(s)
  林慶和、*川久保-安河内友世、溝上顕子、中村　誠司、平田雅人
- Organizer
  第13回西日本骨・関節関連疾患懇話会
- Place of Presentation
  福岡
- Year and Date
  2015-07-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] 前立腺癌におけるオステオカルシンの存在意義2015
- Author(s)
  林慶和、*川久保-安河内友世、中村誠司
- Organizer
  第69回日本口腔科学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] Purification and characterization of the cytotoxic factor secreted from cancer cell line2015
- Author(s)
  Nishinakagawa T, Hazekawa M, *Yasukochi T, Nakashima M.
- Organizer
  The 74th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] Oral squamous carcinoma cell line SQUU-B transfers its metastatic potential to the non-metastatic SQUU-A clone from the same patient through the exosomes2015
- Author(s)
  *Kawakubo-Yasukochi T, Morioka M, Nishinakagawa T, Hazekawa M, Nakamura S, Nakashima M.
- Organizer
  BMB2015 Biochemistry and Molecular Biology
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] Research for component in natural products with anti-tumor invasive potential2015
- Author(s)
  Hazekawa M, Morioka M, Nishinakagawa T, *Yasukochi T, Nakashima M.
- Organizer
  The 74th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] オステオカルシンによる母仔糖脂質代謝機構正常化戦略2014
- Author(s)
  *川久保-安河内友世、近藤皓彦、安武雄、溝上顕子、平田雅人
- Organizer
  第13回西日本骨・関節関連疾患懇話会
- Place of Presentation
  福岡
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] Cathepsin E-induced growth arrest and apoptosis of cancer cells and the related signaling2012
- Author(s)
  Yamamoto K, Kawakubo T, Yasukochi A, Tsukuba T.
- Organizer
  The 85^<th> Annual Meeting of Pharmacological Society
- Place of Presentation
  Kyoto
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E-induced growth arrest and apoptosis of cancer cells and the related signaling2012
- Author(s)
  Yamamoto K., Kawakubo T., Yasukochi A. Tsukuba T
- Organizer
  The 85^<th> Annual Meeting of Pharmacological Society
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] カテプシンEによるガン細胞の増殖抑制とアポトーシス誘導および関連シグナリング2012
- Author(s)
  山本健二、川久保友世、安河内篤、筑波隆幸
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E: related signaling systems, functions and implication in diseases2012
- Author(s)
  Yamamoto K, Kawakubo T, Yasukochi A, Okamoto K, Tsukuba T
- Organizer
  13th International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenia
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] 反復流産病態における妊娠初期脱落膜中マクロファージの cathepsin E の役割2012
- Author(s)
  後藤志信、尾崎康彦、都筑佳苗、安河内篤、川久保友世、国松己歳、山本健二、杉浦真弓
- Organizer
  第17回日本病態プロテアーゼ学会
- Place of Presentation
  浜松
- Year and Date
  2012-08-10
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] 反復流産病態における妊娠初期脱落膜中マクロファージのcathepsin Eの役割2012
- Author(s)
  後藤志信、尾崎康彦、都筑佳苗、安河内篤、川久保友世、国松己歳、山本健二、杉浦真弓
- Organizer
  第17回日本病態プロテアーゼ学会
- Place of Presentation
  浜松
- Year and Date
  2012-08-10
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E : related signaling systems, functions and implication in diseases2012
- Author(s)
  Yamamoto K., Kawakubo T., Yasukochi A., Okamoto K., Tsukuba T
- Organizer
  13th International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  スロベニア
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] カテプシンE結合ペプチド群を例としたP2p (Protei-topeptide)研究展開-「副作用のない創薬」を目指して-2011
- Author(s)
  北村幸一郎、Biyani Madhu、二上雅恵、相田拓洋、後藤仁志、小松将之、川久保友世、鈴木美穂、山本健二、西垣功一
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] マウス皮膚表皮細胞における内在性カテプシンEの役割2011
- Author(s)
  安河内篤、川久保友世、中村誠司、山本健二
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] DMBA/TPA二段階乳頭腫形成モデルにおける表皮カテプシンEの役割2011
- Author(s)
  安河内篤, 他
- Organizer
  第65回日本口腔科学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-22791790
[Presentation] DMBA/TPA二段階乳頭腫形成モデルにおける表皮カテプシンEの役割2011
- Author(s)
  安河内篤、川久保友世、中村誠司、山本健二
- Organizer
  第65回日本口腔科学会学術集会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] DMBA/TPA二段階乳頭腫形成モデルにおける表皮カテプシンEの役割2011
- Author(s)
  安河内篤、川久保友世、中村誠司、山本健二
- Organizer
  第65回日本口腔科学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Role of cathepsin E in deciduas of patients with recurrent miscarriage2011
- Author(s)
  Goto S, Ozaki Y, Kitaori T, Yasukochi A, Kawakubo T, Sugiura M, Yamamoto K
- Organizer
  7^<th> General Meeting of the International Proteolysis Society
- Place of Presentation
  San Diego (USA)
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] 反復流産病態における妊娠初期頸管粘液中Cathepsin Eの役割2011
- Author(s)
  後藤志信、尾崎康彦、大林勇輝、北折珠央、平光由衣乃、安河内篤、川久保友世、山本健二、杉浦真弓
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E is essential for proper mammogenesis2010
- Author(s)
  Kawakubo T, Yasukochi A, Yamamoto K
- Organizer
  12^<th> Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz (Slovenia)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Novel functions of cathepsin E in epidermal differentiation and aging2010
- Author(s)
  Kawakubo T, Yasukochi A, Yamamoto K
- Organizer
  12^<th> Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz (Slovenia)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Analysis of cathepsin E function in epidermal differentiation using a model of DMBA/TPA- induced skin papillomas2010
- Author(s)
  Yasukochi A, Kawakubo T, Yamamoto K
- Organizer
  12th Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz (Slovenia)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Transcription factor Spl regulates the expression of the murine cathepsin E in gastric adenosarcoma cells2010
- Author(s)
  Okamoto K, Okamoto Y, Kawakubo T, Yamamoto K, Tsukuba T
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E: related signaling systems, functions and implication in diseases2010
- Author(s)
  Yamamoto K, Kawakubo T, Yasukochi A, Okamoto K, Tsukuba T
- Organizer
  13th International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenis
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Cathepsin E is essential for proper mammogenesis2010
- Author(s)
  Kawakubo T, Yasukochi A, Yamamoto K
- Organizer
  12th Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz (Slovenia)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] Analysis of cathepsin E function in epidermal differentiation using a model of DMBA/TPA-induced skin papillomas2010
- Author(s)
  Yasukochi A, Kawakubo T, Yamamoto K.
- Organizer
  12^<th> Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz (Slovenia)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22390350
[Presentation] The Role of Cathepsin E on Tumor Growth and Metastasis.2010
- Author(s)
  Kawakubo, T.
- Organizer
  第52回歯科基礎医学会学術大会・総会
- Place of Presentation
  タワーホール船堀(東京都)
- Data Source
  KAKENHI-PROJECT-22791790
[Presentation] Cathepsin E is Essential for Proper Mammogenesis.2010
- Author(s)
  Kawakubo, T., et al.
- Organizer
  The 12^<th> Symposium on PROTEASES, INHIBITORS AND BIOLOGICAL CONTROL
- Place of Presentation
  Portoroz, Slovenia
- Data Source
  KAKENHI-PROJECT-22791790
[Presentation] Combination of cathepsin E and the anticancer drug doxorubicin for enhanced cytotoxicity of human prostate carcinoma cells2009
- Author(s)
  Yasukochi, A., et al.
- Organizer
  6^<Th> General Meeting of the International Proteolysis Society
- Place of Presentation
  Australia
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Association of cathepsin E deficiency with transition from normal development to neoplastic lesions in mammary glands2009
- Author(s)
  Kawakubo, T., et al.
- Organizer
  6^<Th> General Meeting of the International Proteolysis Society
- Place of Presentation
  Australia
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Comparative genomic profiling of mouse mammary glands using DNA Microarrays : Identification of cathepsin E-target genes2008
- Author(s)
  Kawakubo T, et al.
- Organizer
  11^<th> International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  Slovenia
- Year and Date
  2008-08-31
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] カテプシンEと抗腫瘍剤の併用による抗腫瘍効果の増強作用2008
- Author(s)
  安河内篤, 他
- Organizer
  日本病態プロテアーゼ学会
- Place of Presentation
  大阪
- Year and Date
  2008-08-23
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Sensitization for anti-cancer drug-induced apoptosis by cathepsin E2008
- Author(s)
  Yasukochi A, et al.
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Identification of cathepsin E target genes in mouse mammary gland2008
- Author(s)
  Kawakubo T, et al.
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Sensitization for anti-tumor drug-induced apoptosis in tumor cells by cathepsin E2008
- Author(s)
  Yasukochi A, et al.
- Organizer
  11^<th> International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  Slovenia
- Year and Date
  2008-08-31
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Identification of differentially expressed markers in cathepsin E-deficient mouse mammary gland2008
- Author(s)
  Kawakubo T, et al.
- Organizer
  日本細胞生物学会
- Place of Presentation
  横浜
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Effect of doxorubicin on cathepsin E-mediated tumor cell apoptosis2008
- Author(s)
  Yasukochi A, et al.
- Organizer
  日本細胞生物学会
- Place of Presentation
  横浜
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] カテプシンEによるTRAIL誘導性アポトーシスと感受性調節機構2008
- Author(s)
  川久保友世, 他
- Organizer
  歯科基礎医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Association of cathepsin E with host defense against tumor cells2007
- Author(s)
  川久保友世, 他
- Organizer
  5^<th> General Meeting of the International Proteolysis Society
- Place of Presentation
  ギリシア
- Year and Date
  2007-10-21
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Cathepsin E-mediated immunological surveillance on tumor2007
- Author(s)
  川久保友世, 他
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Cathepsin E exerts tumoricidal activity through generation of TRAIL From the tumor cell surface2007
- Author(s)
  川久保友世, 他
- Organizer
  第59回日本細胞生物学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2007-05-28
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] A new strategy for combinational cancer therapy using cathepsin E2007
- Author(s)
  安河内篤, 他
- Organizer
  5^<th> General Meeting of the International Proteolvsis Society
- Place of Presentation
  ギリシア
- Year and Date
  2007-10-21
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] 腫瘍免疫におけるカテプシンEの役割2007
- Author(s)
  川久保友世, 他
- Organizer
  第49回歯科基礎医学会
- Place of Presentation
  北海道大学
- Year and Date
  2007-08-29
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] 動脈硬化発症機構におけるオステオカルシンの役割
- Author(s)
  近藤皓彦、*川久保-安河内友世、溝上顕子、平田雅人
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] 継続的なオステオカルシンの経口投与による糖代謝への影響とその体内動態
- Author(s)
  溝上顕子、安武雄、東泉、*川久保-安河内友世、竹内弘、平田雅人
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] 超高齢化社会における歯科基礎医学の役割：骨-腸-代謝連関シグナルの解明による全身の健康維持への情報発信
- Author(s)
  平田雅人、溝上顕子、*川久保-安河内友世、竹内弘
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] オステオカルシン経口投与時の体内動態と糖代謝への作用
- Author(s)
  溝上顕子、安武雄、東泉、*川久保-安河内友世、高橋一郎、竹内弘、平田雅人
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] オステオカルシン妊娠期投与による次世代糖脂質代謝制御の可能性
- Author(s)
  *川久保-安河内友世、近藤皓彦、安武雄、溝上顕子、平田雅人
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] 前立腺癌におけるオステオカルシンの役割
- Author(s)
  林慶和、*川久保-安河内友世、溝上顕子、竹内弘、平田雅人
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] BGM flow
- Author(s)
  Hirata M, Mizokami A, *Kawakubo-Yasukochi T, Otani T, Yasutake Y.
- Organizer
  The 55th International Symposium on Biological Regulation and Enzyme Activity in Normal and Neoplastic Tissues.
- Place of Presentation
  Bologna, Italy
- Year and Date
  2014-09-16 – 2014-09-17
- Data Source
  KAKENHI-PROJECT-26861554
[Presentation] オステオカルシン妊娠期投与による母仔糖脂質代謝の正常化
- Author(s)
  *川久保-安河内友世、近藤皓彦、溝上顕子、林慶和、竹内弘、平田雅人
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26861554

1. YAMAMOTO Kenji (40091326)

# of Collaborated Projects: 3 results

# of Collaborated Products: 38 results
2. Nakamura Seiji (60189040)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Hirata Masato (60136471)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 新納宏昭 (20380636)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 森山雅文 (20452774)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 柴田琢磨 (30554505)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 坪井洋人 (80580505)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TSUKUBA Takayuki (30264055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. TAKII Ryosuke (00419558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. KADOWAKI Tomoko (70336080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YAMAATAAKE Kumiko (50622114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SUGIURA Hiroshi (20381882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TOYAMA Tatsuya (30315882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YAMASHITA Hiroko (70332947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 溝上顕子 (70722487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
16. 前原隆 (10637333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 後藤志信 (90591909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 尾崎康彦 (50254280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 自見英治郎 (40276598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 片桐岳信 (80245802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Morioka Masahiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
22. NAGANO Koki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. SUGIURA Mayumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 筑波知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
25. 西垣功一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 竹内弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Yasukochi Tomoyo 安河内 友世 (川久保 友世)

川久保 友世

川久保友世

安河内 友世(川久保友世) ヤスコウチ トモヨ

KAWAKUBO Tomoyo 川久保 知世

Research Projects

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胎内栄養環境が規定する成熟後の肥満・異所性脂肪蓄積の素因形成メカニズムPrincipal Investigator

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出生コホート調査と生物学的実験の融合による肥満素因世代間継承メカニズムの証明Principal Investigator

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妊娠母体栄養が定義する肥満素因と肥満症多様性の経世代エピゲノム解析Principal Investigator

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Molecular mechanism for predisposition to develop oral cancer based on epigenome modification in uteroPrincipal Investigator

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Analysis of cancer pathogenesis regulated by tissue-specific non-coding RNAPrincipal Investigator

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Homeostasis in glycoilipid metabolism-related organs maintained by incretinPrincipal Investigator

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Yasukochi Tomoyo 安河内友世 (川久保友世)

川久保友世

安河内友世(川久保友世) ヤスコウチトモヨ

KAWAKUBO Tomoyo 川久保知世