SAKAMOTO TAKEHARU 坂本毅治

… Alternative Names

SAKAMOTO Takeharu 坂本毅治

Less

Researcher Number	70511418
Other IDs
Affiliation (Current)	2025: 関西医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 関西医科大学, 医学部, 教授 2020: 金沢大学, 医学系, 特任准教授 2018 – 2020: 東京大学, 医科学研究所, 准教授 2010 – 2017: 東京大学, 医科学研究所, 助教
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 50:Oncology and related fields / Basic Section 50010:Tumor biology-related / Tumor biology / Biological Sciences Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Basic Section 50010:Tumor biology-related / Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 50:Oncology and related fields / Tumor biology / Tumor biology
Keywords	Principal Investigator がん / 転移 / マクロファージ / 解糖系 / 細胞老化 / ケミカルラベリング / 化学療法 / shRNAライブラリー / ミトコンドリア / ユビキチンリガーゼ … More / スクリーニング / 低酸素 / Mint3 / HIF / 癌細胞 / siRNAライブラリー … More Except Principal Investigator Mint3 / HIF-1 / MT1-MMP / 浸潤・転移 / がん / 標的治療 / 再発 / 肺腺癌 / MECA-79 / 糖鎖抗原 / がん代謝 / 2-ヒドロキシグルタル酸 / 空間的トランスクリプトーム(VISIUM)解析 / 免疫応答 / 腫瘍免疫 / ASXL1 / 固形腫瘍 / クローン性造血 / 悪性化 / 肝臓 / 浸潤転移 / 膜型マトリックスメタロプロテアーゼ / Invasion / HIF / EphA2 / がん微小環境 / ラミニン / 肝細胞がん / CD90 / EpCAM / がんの増殖・浸潤・転移 / がん幹細胞 / 肝臓がん / HIH-1 / p27RF-Rho / ZF21 / 細胞運動 / リン酸化 / FIH-1 / 増殖 / 浸潤 / がん細胞 / HB-EGF / コラーゲン / プロテアーゼ / 腫瘍形成 Less

Elucidating mechanism of high-grade malignancy of lung adenocarcinoma focusing on carbohydrate antigen MECA-79
- Principal Investigator
  
  齊藤朋人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kansai Medical University
空間的シングルセル解析による大腸腺腫から発がん過程に於ける免疫寛容獲得機構の解明
- Principal Investigator
  
  久松雄一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
がん治療薬誘導性間質細胞老化の分子病態の解明と治療応用Principal Investigator
- Principal Investigator
  
  坂本毅治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kansai Medical University
大腸がんにおけるオンコメタボライト・L-2HGの分子基盤の解明
- Principal Investigator
  
  田畑祥
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Osaka University
転移時のがんー間質相互作用を標識するin vivo ケミカルラベリング法の開発Principal Investigator
- Principal Investigator
  
  坂本毅治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kansai Medical University
Exploring novel mechanisms of chemotherapy-induced metastasisPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Takeharu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kansai Medical University
  Kanazawa University
  The University of Tokyo
Crosstalk between clonal hematopoiesis and solid tumors
- Principal Investigator
  
  Goyama Susumu
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  The University of Tokyo
Analysis of MT1-MMP-dependent molecular pathways in the diversity and transformation of hepatocellular carcinoma
- Principal Investigator
  
  Seiki Motoharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Role of anchorage-independent growth regulation in tumor progressionPrincipal Investigator
- Principal Investigator
  
  Sakamoto Takeharu
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
Comprehensive screening of glycolysis-related genes by synthetic lethalityPrincipal Investigator
- Principal Investigator
  
  Sakamoto Takeharu
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
がん組織における高―中酸素分圧下での新規ＨＩＦ活性化メカニズムの機能解析Principal Investigator
- Principal Investigator
  
  坂本毅治
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Study of MT1-MMP in cancer
- Principal Investigator
  
  SEIKI Motoharu
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
Exploring novel genes that regulate glycolysis using a genome-wide siRNA libraryPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Takeharu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo

[Book] 医学のあゆみ第271巻9号「がん細胞・がん間質細胞特異的な酸素センシング機構を標的としたがん微小環境標的薬剤の開発」2019
- Author(s)
  坂本毅治
- Total Pages
  5
- Publisher
  医試薬出版株式会社
- Data Source
  KAKENHI-PROJECT-19K07659
[Book] 医学のあゆみ「MMPを標的にしたがん微小環境の制御」2016
- Author(s)
  坂本毅治
- Total Pages
  5
- Publisher
  医試薬出版株式会社
- Data Source
  KAKENHI-PROJECT-15K06829
[Book] THE LUNG perspectives vol.23 No.3　「MT1-MMP/Mint3によるHIF-1活性化メカニズム」2015
- Author(s)
  坂本毅治
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-24591313
[Book] 実験医学、「生体における水酸化シグナルを介した低酸素応答」、2015年7月号2015
- Author(s)
  坂本毅治
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24591313
[Book] 実験医学2015年7月号「生体における水酸化シグナルを介した低酸素応答」2015
- Author(s)
  坂本毅治
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K06829
[Book] THE LUNG perspectives　「MT1-MMP/Mint3によるHIF-1活性化メカニズム」2015
- Author(s)
  坂本毅治
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15K06829
[Book] 南山堂：「次世代がん戦略研究updateがん基盤生物学－革新的シーズ育成に向けて－」、「13. MT1-MMP及び周辺分子を標的としたがん組織制御薬剤の開発」2013
- Author(s)
  坂本毅治
- Total Pages
  5
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-24591313
[Book] がんの浸潤・転移第20章細胞外マトリックス(ECM)2011
- Author(s)
  坂本毅治, 清木元治
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-22220014
[Book] がんの浸潤・転移第20章細胞外マトリックス(ECM)2011
- Author(s)
  坂本毅治・清木元治
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-22790846
[Book] がんの浸潤・転移第20章2011
- Author(s)
  坂本毅治・清木元治、南山堂
- Publisher
  細胞外マトリックス(ECM)
- Data Source
  KAKENHI-PROJECT-22790846
[Book] がんの浸潤・転移第20章細胞外マトリックス(ECM)2011
- Author(s)
  坂本毅治・清木元治
- Publisher
  南山堂
- Data Source
  KAKENHI-PUBLICLY-23112505
[Journal Article] L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis2023
- Author(s)
  Tabata Sho、Kojima Yasushi、Sakamoto Takeharu、Igarashi Kaori、Umetsu Ko、Ishikawa Takamasa、Hirayama Akiyoshi、Kajino-Sakamoto Rie、Sakamoto Naoya、Yasumoto Ken-ichi、Okano Keiichi、Suzuki Yasuyuki、Yachida Shinichi、Aoki Masahiro、Soga Tomoyoshi
- Journal Title
  
  Oncogene
  
  Volume: 42 Issue: 16 Pages: 1294-1307
- DOI
  10.1038/s41388-023-02632-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07150, KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-17KK0199, KAKENHI-PROJECT-22K19464, KAKENHI-ORGANIZER-23H04939, KAKENHI-PROJECT-23K24170, KAKENHI-PROJECT-23K28008
[Journal Article] Hypoxia inducible factor‐1 activator munc‐18‐interacting protein 3 promotes tumour progression in urothelial carcinoma2023
- Author(s)
  Ikeda Junichi、Ohe Chisato、Tanaka Noritaka、Yoshida Takashi、Saito Ryoichi、Atsumi Naho、Kobayashi Takashi、Kinoshita Hidefumi、Tsuta Koji、Sakamoto Takeharu
- Journal Title
  
  Clinical and Translational Discovery
  
  Volume: 3 Issue: 1
- DOI
  10.1002/ctd2.158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-19K07659
[Journal Article] Mint3-depletion-induced energy stress sensitizes triple-negative breast cancer to chemotherapy via HSF1 inactivation2023
- Author(s)
  Tanaka Noritaka、Okada Hikari、Yamaguchi Kiyoshi、Seki Masahide、Matsubara Daisuke、Gotoh Noriko、Suzuki Yutaka、Furukawa Yoichi、Yamashita Taro、Inoue Jun-ichiro、Kaneko Shuichi、Sakamoto Takeharu
- Journal Title
  
  Cell Death & Disease
  
  Volume: 14 Issue: 12 Pages: 815-815
- DOI
  10.1038/s41419-023-06352-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-23K18237, KAKENHI-PROJECT-21H02761, KAKENHI-PROJECT-23K28008
[Journal Article] Role of oxygen-sensing mechanism modulator, Mint3, in macrophage-related infl ammation and cancer2023
- Author(s)
  坂本毅治、田中伯享、植松崇之
- Journal Title
  
  Cytometry Research
  
  Volume: 32 Issue: 2 Pages: 1-9
- DOI
  10.18947/cytometryresearch.32.2_1
- ISSN
  0916-6920, 2424-0664
- Year and Date
  2023-04-17
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-23K28008
[Journal Article] 特集がん遺伝子の発見は現代医療を進歩させたか Ⅰ.がん遺伝子研究の新しい展開 RAS遺伝子を中心としたがん治療戦略の確立2023
- Author(s)
  田中伯享、坂本毅治
- Journal Title
  
  生体の科学
  
  Volume: 74 Issue: 4 Pages: 289-294
- DOI
  10.11477/mf.2425201695
- ISSN
  0370-9531, 1883-5503
- Year and Date
  2023-08-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-23K28008
[Journal Article] Spatial and single-cell transcriptomics decipher the cellular environment containing HLA-G+ cancer cells and SPP1+ macrophages in colorectal cancer2023
- Author(s)
  Ozato Y, Mimori K(28番目）,他26名
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 1 Pages: 111929-111929
- DOI
  10.1016/j.celrep.2022.111929
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08908, KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-22H04839, KAKENHI-PROJECT-23K24164, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-23K06662, KAKENHI-PROJECT-23K08128, KAKENHI-PROJECT-21K07179
[Journal Article] MT1-MMP as a Key Regulator of Metastasis2023
- Author(s)
  Tanaka Noritaka、Sakamoto Takeharu
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 17 Pages: 2187-2187
- DOI
  10.3390/cells12172187
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-23K28008
[Journal Article] Mint3 as a Potential Target for Cooling Down HIF-1α-Mediated Inflammation and Cancer Aggressiveness2023
- Author(s)
  Tanaka Noritaka、Sakamoto Takeharu
- Journal Title
  
  Biomedicines
  
  Volume: 11 Issue: 2 Pages: 549-549
- DOI
  10.3390/biomedicines11020549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-19K07659
[Journal Article] Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium.2022
- Author(s)
  Kasai Y, Gan SP, Funaki T, Ohashi-Kumagai Y, Tominaga M, Shiu S-J, Suzuki D, Matsubara D, Sakamoto T, Sakurai-Yageta M, Ito T, Murakami Y.
- Journal Title
  
  Cancer Science
  
  Volume: in press Issue: 5 Pages: 1-2
- DOI
  10.1111/cas.15307
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21539, KAKENHI-PUBLICLY-20H05028, KAKENHI-PROJECT-20H03525, KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-21K07091, KAKENHI-PROJECT-22K19464
[Journal Article] CHIP‐associated mutant ASXL1 in blood cells promotes solid tumor progression2022
- Author(s)
  Liu Xiaoxiao、Sato Naru、Shimosato Yuko、Wang Teh‐Wei、Denda Tamami、Chang Yu‐Hsuan、Yabushita Tomohiro、Fujino Takeshi、Asada Shuhei、Tanaka Yosuke、Fukuyama Tomofusa、Enomoto Yutaka、Ota Yasunori、Sakamoto Takeharu、Kitamura Toshio、Goyama Susumu
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 4 Pages: 1182-1194
- DOI
  10.1111/cas.15294
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03685, KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-22K19539, KAKENHI-PROJECT-20H00537
[Journal Article] Involvement of membrane palmitoylated protein 2 (MPP2) in the synaptic molecular complex at the mouse cerebellar glomerulus2022
- Author(s)
  Tomoki Yamada, Yurika Saitoh, Kiyokazu Kametani, Akio Kamijo, Takeharu Sakamoto, Nobuo Terada
- Journal Title
  
  Histochem Cell Biol
  
  Volume: 158 Issue: 5 Pages: 497-511
- DOI
  10.1007/s00418-022-02137-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11275, KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-19K07659
[Journal Article] Structural and thermodynamical insights into the binding and inhibition of FIH-1 by the N-terminal disordered region of Mint3.2021
- Author(s)
  Ten T, Nagatoishi S, Maeda R, Hoshino M, Nakayama Y, Seiki M, Sakamoto T, Tsumoto K.
- Journal Title
  
  J Biol Chem.
  
  Volume: 297 Issue: 5 Pages: 101304-101304
- DOI
  10.1016/j.jbc.2021.101304
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] TGF-β-dependent reprogramming of amino acid metabolism induces epithelial?mesenchymal transition in non-small cell lung cancers2021
- Author(s)
  Nakasuka Fumie, Tabata Sho, Sakamoto Takeharu, Hirayama Akiyoshi, Ebi Hiromichi, Yamada Tadaaki, Umetsu Ko, Ohishi Maki, Ueno Ayano, Goto Hisatsugu, Sugimoto Masahiro, Nishioka Yasuhiko, Yamada Yasuhiro, Tomita Masaru, Sasaki Atsuo T, Yano Seiji, Soga Tomoyoshi
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1-12
- DOI
  10.1038/s42003-021-02323-7
- NAID
  120007178465
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03668, KAKENHI-PROJECT-20H03542, KAKENHI-PROJECT-19J22093, KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-17KK0199, KAKENHI-PLANNED-20H05743
[Journal Article] Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock2021
- Author(s)
  Takeharu Sakamoto, Yuya Fukui, Yasumitsu Kondoh, Kaori Honda, Takeshi Shimizu, Toshiro Hara, Tetsuro Hayashi, Yurika Saitoh, Yoshinori Murakami, Jun-Ichiro Inoue, Shuichi Kaneko, Hiroyuki Osada, Motoharu Seiki
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1165-1165
- DOI
  10.1038/s42003-021-02701-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10764, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-21K11275, KAKENHI-PLANNED-17H06412
[Journal Article] 炎症による転移の制御2021
- Author(s)
  坂本　毅治
- Journal Title
  
  月刊「細胞」2021年 2月号
  
  Volume: 53 Pages: 12-15
- Data Source
  KAKENHI-PROJECT-19K07659
[Journal Article] Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophages2021
- Author(s)
  Uematsu Takayuki、Tsuchiya Kohsuke、Kobayashi Noritada、Seiki Motoharu、Inoue Jun-ichiro、Kaneko Shuichi、Sakamoto Takeharu
- Journal Title
  
  Cell Death and Disease
  
  Volume: 12 Issue: 4 Pages: 404-404
- DOI
  10.1038/s41419-021-03691-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07106, KAKENHI-PROJECT-19K07659
[Journal Article] MMPを標的としたがん微小環境改変治療法の可能性2021
- Author(s)
  坂本　毅治
- Journal Title
  
  実験医学増刊
  
  Volume: 39 Pages: 1962-1967
- Data Source
  KAKENHI-PROJECT-19K07659
[Journal Article] Mint3 depletion restricts tumor malignancy of pancreatic cancer cells by decreasing SKP2 expression via HIF-12020
- Author(s)
  Kanamori Akane、Matsubara Daisuke、Saitoh Yurika、Fukui Yuya、Gotoh Noriko、Kaneko Shuichi、Seiki Motoharu、Murakami Yoshinori、Inoue Jun-ichiro、Sakamoto Takeharu
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 39 Pages: 6218-6230
- DOI
  10.1038/s41388-020-01423-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-19K22557, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02679
[Journal Article] Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo.2020
- Author(s)
  Omori S, Wang TW, Johmura Y, ..., Sakamoto T (15番目), ..., Nakanishi M.
- Journal Title
  
  Cell Metab
  
  Volume: 32 Issue: 5 Pages: 814-828
- DOI
  10.1016/j.cmet.2020.09.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-19K12215, KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21497, KAKENHI-PROJECT-20K21612, KAKENHI-PROJECT-19KK0216, KAKENHI-PROJECT-17H06095, KAKENHI-PLANNED-17H06328, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PUBLICLY-20H04940, KAKENHI-PUBLICLY-20H05025, KAKENHI-PROJECT-20H00567, KAKENHI-PROJECT-19H03413, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20H03707, KAKENHI-PROJECT-19J01606, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-17K07132, KAKENHI-PROJECT-18K15826, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06024, KAKENHI-PROJECT-20H03162, KAKENHI-PROJECT-20H03474
[Journal Article] Munc18-1-interacting protein 3 mitigates renal fibrosis through protection of tubular epithelial cells from apoptosis.2020
- Author(s)
  Nasu K, Kawakami T, Shinohara A, Sakamoto T, Nangaku M.
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 35 Issue: 4 Pages: 576-586
- DOI
  10.1093/ndt/gfz177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-18H02824
[Journal Article] Mint3 is dispensable for pancreatic and kidney functions in mice.2020
- Author(s)
  Chung Y, Saitoh Y, Hayashi T, Fukui Y, Terada N, Seiki M, Murakami Y, Sakamoto T.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 24 Pages: 100872-100872
- DOI
  10.1016/j.bbrep.2020.100872
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07659
[Journal Article] EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells.2020
- Author(s)
  Yoshino S, Matsui Y, Fukui Y, Seki M, Yamaguchi K, Kanamori A, Saitoh Y, Shimamura T, Suzuki Y, Furukawa Y, Kaneko S, Seiki M, Murakami Y, Inoue JI, Sakamoto T.
- Journal Title
  
  Sci Rep
  
  Volume: 10 Issue: 1 Pages: 9275-9275
- DOI
  10.1038/s41598-020-66455-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21832, KAKENHI-INTERNATIONAL-16K21739, KAKENHI-ORGANIZER-16H06573, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-19H05210, KAKENHI-PUBLICLY-20H04841, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-18H03207
[Journal Article] Structures and Molecular Composition of Schmidt-Lanterman Incisures2019
- Author(s)
  Nobuo Terada, Yurika Saitoh, Akio Kamijo, Junji Yamauchi, Nobuhiko Ohno, Takeharu Sakamoto
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 1190 Pages: 181-198
- DOI
  10.1007/978-981-32-9636-7_12
- ISBN
  9789813296350, 9789813296367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10764, KAKENHI-PROJECT-19K07659
[Journal Article] Electron microscopic observation of photoreceptor cells in directly inserted anesthetized Drosophila into a high-pressure freezing unit2019
- Author(s)
  Terada H, Saitoh Y, Kametani K, Sakaguchi M, Sakamoto T, Kamijo A, Terada N
- Journal Title
  
  Microsc Res Tech
  
  Volume: 82 Issue: 3 Pages: 244-249
- DOI
  10.1002/jemt.23166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06829, KAKENHI-PROJECT-16K08463
[Journal Article] Scaffold protein Lin7 family in membrane skeletal protein complex in mouse seminiferous tubules.2019
- Author(s)
  Kamijo A, Saitoh Y, Sakamoto T, Kubota H, Yamauchi J, Terada N.
- Journal Title
  
  Histochem Cell Biol.
  
  Volume: 152 Issue: 5 Pages: 333-343
- DOI
  10.1007/s00418-019-01807-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07659
[Journal Article] Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment.2018
- Author(s)
  Tsubaki T, Kadonosono T, Sakurai S, Shiozawa T, Goto T, Sakai S, Kuchimaru T, Sakamoto T, Watanabe H, Kondoh G, Shinae Kizaka-Kondoh.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 13 Pages: 11209-11226
- DOI
  10.18632/oncotarget.24359
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06829, KAKENHI-PROJECT-15J02021, KAKENHI-PROJECT-15K21098
[Journal Article] The membrane palmitoylated protein, MPP6, is involved in myelin formation in the mouse peripheral nervous system2018
- Author(s)
  Saitoh Yurika、Kamijo Akio、Yamauchi Junji、Sakamoto Takeharu、Terada Nobuo
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: 151 Issue: 5 Pages: 385-394
- DOI
  10.1007/s00418-018-1745-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10764, KAKENHI-PROJECT-15K06829, KAKENHI-PROJECT-16K08463
[Journal Article] Integrated functions of membrane-type 1 matrix metalloproteinase in regulating cancer malignancy: beyond a proteinase.2017
- Author(s)
  Sakamoto T, Seiki M.
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Issue: 6 Pages: 1095-1100
- DOI
  10.1111/cas.13231
- NAID
  120006336015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06829
[Journal Article] Deficiency of a membrane skeletal protein, 4.1G, results in myelin abnormalities in the peripheral nervous system.2017
- Author(s)
  Saitoh Y, Ohno N, Yamauchi J, Sakamoto T, Terada N.
- Journal Title
  
  Histochem Cell Biol
  
  Volume: 148 Issue: 6 Pages: 597-606
- DOI
  10.1007/s00418-017-1600-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06829, KAKENHI-PROJECT-16K08463
[Journal Article] Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin α5β1 and tumour growth.2017
- Author(s)
  Nakaoka HJ, Tanei Z, Hara T, Weng JS, Kanamori A, Hayashi T, Sato H, Orimo A, Otsuji K, Tada K, Morikawa T, Sasaki T, Fukayama M, Seiki M, Murakami Y, Sakamoto T.
- Journal Title
  
  Oncogenesis
  
  Volume: 6 Issue: 5 Pages: e334-e334
- DOI
  10.1038/oncsis.2017.27
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06829
[Journal Article] Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.2017
- Author(s)
  Hara T, Nakaoka HJ, Hayashi T, Mimura K, Hoshino D, Inoue M, Nagamura F, Murakami Y, Seiki M, Sakamoto T.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 114 Issue: 22
- DOI
  10.1073/pnas.1703171114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06829, KAKENHI-PROJECT-17K08904, KAKENHI-PROJECT-16H04695
[Journal Article] Mint3 in bone marrow-derived cells promotes lung metastasis in breast cancer model mice.2017
- Author(s)
  Hara T, Murakami Y, Seiki M, Sakamoto T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 490 Issue: 3 Pages: 688-692
- DOI
  10.1016/j.bbrc.2017.06.102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06829
[Journal Article] Mint3/Apba3 depletion ameliorates severe murine influenza pneumonia and macrophage cytokine production in response to the influenza virus.2016
- Author(s)
  Uematsu T, Fujita T, Nakaoka HJ, Hara T, Kobayashi N, Murakami Y, Seiki M, Sakamoto T
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 37815-37815
- DOI
  10.1038/srep37815
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06829, KAKENHI-PROJECT-16K09585, KAKENHI-PROJECT-16H04695
[Journal Article] Mint3 potentiates TLR3/4- and RIG-I-induced IFN-β expression and antiviral immune responses.2016
- Author(s)
  Huai W, Song H, Yu Z, Wang W, Han L, Sakamoto T, Seiki M, Zhang L, Zhang Q, and Zhao W.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: - Issue: 42 Pages: 11925-11930
- DOI
  10.1073/pnas.1601556113
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06829
[Journal Article] The ERK-signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux.2016
- Author(s)
  Yoshino S, Hara T, Nakaoka HJ, Kanamori A, Murakami Y, Seiki M, Sakamoto T.
- Journal Title
  
  Cell Discov.
  
  Volume: 2 Issue: 1 Pages: 16019-16019
- DOI
  10.1038/celldisc.2016.19
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06829, KAKENHI-PROJECT-16H04695
[Journal Article] NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells2016
- Author(s)
  1.Nakaoka HJ, Hara T, Yoshino S, Kanamori A, Matsui Y, Shimamura T, Sato H, Murakami Y, Seiki M, Sakamoto T
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 22784-22784
- DOI
  10.1038/srep22784
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06829, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-24591313, KAKENHI-PROJECT-25460382, KAKENHI-PROJECT-26640121, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-25290051, KAKENHI-PUBLICLY-16H01572, KAKENHI-PROJECT-15H05325, KAKENHI-PROJECT-16H04695
[Journal Article] Hypoxia-inducible factor 1 regulation through cross talk between mTOR and MT1-MMP.2014
- Author(s)
  Sakamoto T, Weng JS, Hara T, Yoshino S, Kozuka-Hata H, Oyama M, Seiki M.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 34(1) Issue: 1 Pages: 30-42
- DOI
  10.1128/mcb.01169-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-23510254, KAKENHI-PROJECT-24591313
[Journal Article] Hypoxia-inducible factor 1 regulation through cross talk between mTOR and MT1-MMP2014
- Author(s)
  Sakamoto, T., Weng, J. S., Hara, T., Yoshino, S., Kozuka-Hata, H., Oyama, M., and Seiki, M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 34(1) Pages: 30-42
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Investigation of a MMP-2 Activity-Dependent Anchoring Probe for Nuclear Imaging of Cancer2014
- Author(s)
  Temma T, Hanaoka H, Yonezawa A, Kondo N, Sano K, Sakamoto T, Seiki M, Ono M, Saji H.
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 7 Pages: e102180-e102180
- DOI
  10.1371/journal.pone.0102180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591313
[Journal Article] Genetic screening of new genes responsible for cellular adaptation to hypoxia using a genome-wide shRNA library.2012
- Author(s)
  Yoshino S, Hara T, Weng JS, Takahashi Y, Seiki M, Sakamoto T.
- Journal Title
  
  PLoS One.
  
  Volume: 7(4) Issue: 4 Pages: e35590-e35590
- DOI
  10.1371/journal.pone.0035590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-24591313, KAKENHI-PUBLICLY-23112505
[Journal Article] Genetic Screening of New Genes Responsible for Cellular Adaptation to Hypoxia Using a Genome-Wide shRNA Library2012
- Author(s)
  Yoshino S, Hara T, Weng JS, Takahashi Y, Seiki M, Sakamoto T
- Journal Title
  
  PloS one
  
  Volume: 7
- URL
  http://dx.plos.org/10.1371/journal.pone.0035590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] MT1-MMP plays a critical role in henatopoiesis by regulating HIF-mediated chemo-/cytokine gene transcription within niche cells.2012
- Author(s)
  Chiemi Nishida, Kaori Kusubata, Yoshihiko Tashiro, Ismael Gritli, Aki Sato, Makiko Ohki-Koizumi, Yohei Morita, Makoto Nagano, Takeharu Sakamoto, Naohiko Koshikawa, Takahiro Kuchimaru, Shinae Kizaka-Kondoh, Motoharu Seiki, Hiromitsu Nakauchi, Beate Heissig, and Koichi Hattori.
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 23 Pages: 5404-5416
- DOI
  10.1182/blood-2011-11-390849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00480, KAKENHI-PROJECT-12J04973, KAKENHI-PROJECT-22591762, KAKENHI-PUBLICLY-23013009, KAKENHI-PROJECT-23591371, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24591313, KAKENHI-PROJECT-24591382, KAKENHI-PLANNED-22112007, KAKENHI-PLANNED-22112009, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23112505
[Journal Article] Genetic screening of new genes responsible for cellular adaptation to hypoxia using a genome-wide shRNA library2012
- Author(s)
  Yoshino S, Hara T, Weng JS, Takahashi Y, Seiki M, Sakamoto T
- Journal Title
  
  PLoS ONE
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112505
[Journal Article] MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells2012
- Author(s)
  Nishida, C., Kusubata, K., Tashiro, Y., Gritli, I., Sato, A., Ohki-Koizumi, M., Morita, Y., Nagano, M., Sakamoto, T., Koshikawa, N., Kuchimaru, T., Kizaka-Kondoh, S., Seiki, M., Nakauchi, H., Heissig, B., and Hattori, K
- Journal Title
  
  Blood
  
  Volume: 119(23) Pages: 5405-16
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Genetic screening of new genes responsible for cellular adaptation to hypoxia using a genome-wide shRNA library2012
- Author(s)
  Yoshino S, Hara T, Weng JS, Takahashi Y, Seiki M, Sakamoto T
- Journal Title
  
  PLoS ONE
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] Genetic dissection of proteolytic and non-proteolytic contributions of MT1-MMP to macrophage invasion2011
- Author(s)
  Hara T, Mimura K, Seiki M, Sakamoto T
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 413 Pages: 277-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] Genetic dissection of proteolytic and non-proteolytic contributions of MT1-MMP to macrophage invasion.2011
- Author(s)
  Hara T, Mimura K, Seiki M, Sakamoto T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 23;413(2) Issue: 2 Pages: 277-81
- DOI
  10.1016/j.bbrc.2011.08.085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-22790846, KAKENHI-PUBLICLY-23112505
[Journal Article] Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock2011
- Author(s)
  Hara, T., K. Mimura, T. Abe, G. Shioi, M. Seiki, and T. Sakamoto
- Journal Title
  
  J Biol Chem
  
  Volume: 286(37) Pages: 32542-51
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center2011
- Author(s)
  Nagano, M., D. Hoshino, T. Sakamoto, T. Akizawa, N. Koshikawa, and M. Seiki
- Journal Title
  
  Cell Adh Migr
  
  Volume: 5(1) Pages: 23-8
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.2011
- Author(s)
  Nagano M, Hoshino D, Sakamoto T, Akizawa T, Koshikawa N, Seiki M.
- Journal Title
  
  Cell Adh Migr.
  
  Volume: 5(1) Pages: 23-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock2011
- Author(s)
  Hara T, Mimura K, Abe T, Shioi G, Seiki M, Sakamoto T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 16;286(37) Issue: 37 Pages: 32542-51
- DOI
  10.1074/jbc.m111.271726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-22790846, KAKENHI-PUBLICLY-23112505
[Journal Article] ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center2011
- Author(s)
  Nagano M, Hoshino D, Sakamoto T, Akizawa T, Koshikawa N, Seiki M
- Journal Title
  
  Cell adhesion & migration
  
  Volume: 5 Pages: 23-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloproteinase2011
- Author(s)
  Sakamoto T, Niiya D, Seiki M
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 286 Pages: 14691-14704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloproteinase2011
- Author(s)
  Sakamoto, T., D. Niiya, and M. Seiki
- Journal Title
  
  J Biol Chem
  
  Volume: 286(16) Pages: 14691-704
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix2011
- Author(s)
  Sakamoto T, Niiya D, Seiki M
- Journal Title
  
  metalloproteinase.
  
  Volume: J Biol Chem 22;286(16) Issue: 16 Pages: 14691-704
- DOI
  10.1074/jbc.m110.188714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-22790846, KAKENHI-PUBLICLY-23112505
[Journal Article] Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock2011
- Author(s)
  Hara T, Mimura K, Abe T, Shioi G, Seiki M, Sakamoto T
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 286 Pages: 32542-32551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] Genetic dissection of proteolytic and non-proteolytic contributions of MT1-MMP to macrophage invasion2011
- Author(s)
  Hara, T., K. Mimura, M. Seiki, and T. Sakamoto
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 413(2) Pages: 277-81
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] A membrane protease regulates energy production in macrophages by activating hypoxia-inducible factor-1 via a non-proteolytic mechanism2010
- Author(s)
  坂本毅治、清木元治, 2/2番目
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 29951-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] A membrane protease regulates energy production in macrophages by activating hypoxia-inducible factor-1 via a non-proteolytic mechanism.2010
- Author(s)
  Sakamoto T, Seiki M.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285(39) Pages: 29951-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] A membrane protease regulates energy production in macrophages by activating hypoxia-inducible factor-1 via a non-proteolytic mecha nism2010
- Author(s)
  Sakamoto, T. and M. Seiki
- Journal Title
  
  J Biol Chem
  
  Volume: 285(39) Pages: 29951-64
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] A membrane protease regulates energy production in macrophages by activating hypoxia-inducible factor-1 via a non-proteolytic mechanism2010
- Author(s)
  Sakamoto T, Seiki M
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 285 Pages: 29951-29964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] ZF21 protein regulates cell adhesion and motility2010
- Author(s)
  Nagano M, Hoshino D, Sakamoto T, Kawasaki N, Koshikawa N, Seiki M
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 285 Pages: 21013-21022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] ZF21 protein regulates cell adhesion and motility2010
- Author(s)
  Nagano, M., D. Hoshino, T. Sakamoto, N. Kawasaki, N. Koshikawa, and M. Seiki
- Journal Title
  
  J Biol Chem
  
  Volume: 285(27) Pages: 21013-22
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] ZF21 protein regulates cell adhesion and motility.2010
- Author(s)
  Nagano M, Hoshino D, Sakamoto T, Kawasaki N, Koshikawa N, Seiki M.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285(27) Pages: 21013-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790846
[Journal Article] Genetic screening of new genes responsible for cellular adaptation to hypoxia using a genome-wide shRNA library
- Author(s)
  Yoshino, S., T . Hara, J. S. Weng, Y . Takahashi, M. Seiki, and T . Sakamoto
- Journal Title
  
  PLos One
  
  Volume: 7(4)
- Data Source
  KAKENHI-PROJECT-22220014
[Patent] Mint3阻害剤2015
- Inventor(s)
  坂本毅治、清木元治、長田裕之、斉藤臣雄、近藤恭光、清水猛
- Industrial Property Rights Holder
  坂本毅治、清木元治、長田裕之、斉藤臣雄、近藤恭光、清水猛
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-053939
- Filing Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] KRAS阻害剤によるHIF-1Aの発現制御機構2023
- Author(s)
  田中伯享, 坂本毅治
- Organizer
  第46回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] 細胞内酸素センシング調節機構を標的としたがん・炎症の制御2023
- Author(s)
  坂本毅治
- Organizer
  第64 回日本組織細胞化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] 細胞内酸素センシング調節機構を標的としたがん・炎症の制御2023
- Author(s)
  坂本毅治
- Organizer
  第64 回日本組織細胞化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K28008
[Presentation] KRAS阻害剤によるHIF-1Aの発現制御機構2023
- Author(s)
  田中伯享, 坂本毅治
- Organizer
  第46回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K28008
[Presentation] HIF-1 activator Mint3 promotes tumor progression in urothelial carcinoma2023
- Author(s)
  Ikeda J, Ohe C, Tanaka N, Yoshida T, Saito R, Atsumi N, Kobayashi T, Kinoshita H, Tsuta K, Sakamoto T
- Organizer
  第38回欧州泌尿器科学会議(EAU23 38th Annual EAU Congress)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] The potential effect of KRAS inhibitors on tumor microenvironments2023
- Author(s)
  Noritaka Tanaka, Takeharu Sakamoto
- Organizer
  AACR-NCI-EORTC INTERNATIONAL CONFERENCE ON MOLECULAR TARGETS AND CANCER THERAPEUTICS 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28008
[Presentation] HIF-1 activator Mint3 promotes tumor progression in urothelial carcinoma2023
- Author(s)
  Ikeda J, Ohe C, Tanaka N, Yoshida T, Saito R, Atsumi N, Kobayashi T, Kinoshita H, Tsuta K, Sakamoto T
- Organizer
  第38回欧州泌尿器科学会議(EAU23 38th Annual EAU Congress)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] KRAS阻害剤によるHIF-1α発現制御メカニズム2023
- Author(s)
  田中伯享、坂本毅治
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] KRAS阻害剤によるHIF-1α発現制御メカニズム2023
- Author(s)
  田中伯享、坂本毅治
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K28008
[Presentation] The potential effect of KRAS inhibitors on tumor microenvironments2023
- Author(s)
  Noritaka Tanaka, Takeharu Sakamoto
- Organizer
  AACR-NCI-EORTC INTERNATIONAL CONFERENCE ON MOLECULAR TARGETS AND CANCER THERAPEUTICS 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] KRAS阻害剤に対する耐性化とEMTに関する解析2023
- Author(s)
  田中伯享、坂本毅治
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-23K28008
[Presentation] KRAS阻害剤に対する耐性化とEMTに関する解析2023
- Author(s)
  田中伯享、坂本毅治
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] Mint3阻害はin vivoでトリプルネガティブ乳がんを化学療法感受性にする2022
- Author(s)
  坂本毅治, 田中伯享, 山口貴世志, 松原大祐, 古川洋一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] KRAS阻害剤ががん微小環境に与える影響に関する検討2022
- Author(s)
  田中伯享, 坂本毅治
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] T細胞リンパ腫と血管内皮細胞間における細胞接着分子CADM1のトランス・ホモ結合は臓器浸潤を促進する2022
- Author(s)
  笠井優, 坂本毅治, 伊東剛, 村上善則
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Mint3阻害はin vivoでトリプルネガティブ乳がんを化学療法感受性にする2022
- Author(s)
  坂本毅治, 田中伯享, 山口貴世志, 松原大祐, 古川洋一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] KRAS阻害剤ががん微小環境のリプログラミングにおよぼす影響に関する解析2022
- Author(s)
  田中伯享, 坂本毅治
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] The collateral effects of KRAS inhibitors on tumor microenvironment2022
- Author(s)
  Noritaka Tanaka, Takeharu Sakamoto
- Organizer
  The 26th JFCR－ISCC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Mint3は膵癌でHIF-1を介してSKP2を制御する2022
- Author(s)
  金森茜, 村上善則, 井上純一郎, 坂本毅治
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] The collateral effects of KRAS inhibitors on tumor microenvironment2022
- Author(s)
  Noritaka Tanaka, Takeharu Sakamoto
- Organizer
  The 26th JFCR－ISCC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] がんにおける低酸素応答関連因子に対するKRAS阻害剤の影響2022
- Author(s)
  田中伯享, 坂本毅治
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] KRAS阻害剤ががん微小環境のリプログラミングにおよぼす影響に関する解析2022
- Author(s)
  田中伯享, 坂本毅治
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] KRAS阻害剤に対する耐性と転移能に関する解析2022
- Author(s)
  田中伯享, 坂本毅治
- Organizer
  第31回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] 酸素センシング機構によるマクロファージ機能制御のがん、炎症性疾患における役割2022
- Author(s)
  坂本毅治, 植松崇之
- Organizer
  第32回日本サイトメトリー学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] T細胞リンパ腫と血管内皮細胞間における細胞接着分子CADM1のトランス・ホモ結合は臓器浸潤を促進する2022
- Author(s)
  笠井優, 坂本毅治, 伊東剛, 村上善則
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] がんにおける低酸素応答関連因子に対するKRAS阻害剤の影響2022
- Author(s)
  田中伯享, 坂本毅治
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] KRAS阻害剤に対する耐性と転移能に関する解析2022
- Author(s)
  田中伯享, 坂本毅治
- Organizer
  第31回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] Listeria monocytogenes感染におけるHIF-1活性化因子Mint3を介した宿主応答機構の解析2022
- Author(s)
  植松崇之、土屋晃介、小林憲忠、坂本毅治
- Organizer
  第95回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Mint3は尿路上皮癌における予後不良因子である2022
- Author(s)
  池田純一, 田中伯享, 齊藤亮一, 小林恭, 木下秀文, 坂本毅治
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Mint3は尿路上皮癌における予後不良因子である2022
- Author(s)
  池田純一, 田中伯享, 齊藤亮一, 小林恭, 木下秀文, 坂本毅治
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] Mint3は高分化型AFP陰性肝細胞癌に対する新規治療標的因子になり得る2022
- Author(s)
  岡田光, 山下太郎, 坂本毅治, 金子周一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] 化学療法誘導性肺転移の新規メカニズム2022
- Author(s)
  坂本毅治, 田中伯享
- Organizer
  第31回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] KRAS阻害剤ががん微小環境に与える影響に関する検討2022
- Author(s)
  田中伯享, 坂本毅治
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] 化学療法誘導性肺転移の新規メカニズム2022
- Author(s)
  坂本毅治, 田中伯享
- Organizer
  第31回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] Mint3は高分化型AFP陰性肝細胞癌に対する新規治療標的因子になり得る2022
- Author(s)
  岡田光, 山下太郎, 坂本毅治, 金子周一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] 酸素センシング機構によるマクロファージ機能制御のがん、炎症性疾患における役割2022
- Author(s)
  坂本毅治, 植松崇之
- Organizer
  第32回日本サイトメトリー学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19464
[Presentation] Mint3の抑制はin vivoでトリプルネガティブ乳がんを化学療法感受性にする2022
- Author(s)
  坂本毅治, 田中伯享, 山口貴世志, 松原大祐, 古川洋一
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Mint3は膵癌でHIF-1を介してSKP2を制御する2022
- Author(s)
  金森茜, 村上善則, 井上純一郎, 坂本毅治
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Listeria monocytogenes感染におけるHIF-1活性化因子Mint3を介した宿主応答機構の解析2021
- Author(s)
  植松崇之、土屋晃介、小林憲忠、清木元治、井上純一郎、金子周一、坂本毅治
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] 宿主Mint3は肺において化学療法誘導性前転移ニッチ形成を促進する2021
- Author(s)
  坂本毅治
- Organizer
  第30回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] がん細胞と間質細胞での酸素センシング機構の制御はがん進展を制御する2021
- Author(s)
  坂本　毅治
- Organizer
  第94回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] がん微小環境の酸素センシング機構を標的とした創薬研究2021
- Author(s)
  坂本毅治
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Mint3-FIH-1相互作用の薬理的阻害は腫瘍の増殖、転移、エンドトキシンショックを減弱させる2021
- Author(s)
  坂本毅治，福井優也, 近藤恭光 , 本田香織 ,清水猛, 原敏朗 , 林哲郎, 齊藤百合花, 村上善則, 井上純一郎, 金子周一, 長田裕之, 清木元治.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Mint3はトリプルネガティブ乳がん細胞の腫瘍組織中での抗がん剤抵抗性を制御する2021
- Author(s)
  坂本毅治
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] 宿主Mint3は化学療法誘導性転移を促進する2020
- Author(s)
  坂本　毅治
- Organizer
  第29回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Mint3はトリプルネガティブ乳がん細胞の腫瘍組織中での抗がん剤抵抗性を制御する2020
- Author(s)
  坂本　毅治
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] がん組織特異的酸素センシング制御機構を標的とした創薬研究2020
- Author(s)
  坂本　毅治
- Organizer
  AMED/BINDS　利用セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] 乳がん化学療法誘導性肺転移の新規メカニズム2019
- Author(s)
  坂本毅治
- Organizer
  第3回　乳がん・転移若手研究会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Host Mint3 promotes metastatic niche formation2019
- Author(s)
  坂本毅治
- Organizer
  第3回がんと代謝研究会若手の会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Mint3阻害による膵癌の制御2019
- Author(s)
  坂本毅治
- Organizer
  第2回がんと代謝研究会若手の会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3はSKP2発現を介して膵癌細胞の増殖を促進する2019
- Author(s)
  坂本毅治
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] 化学療法誘導性転移の新規メカニズム2019
- Author(s)
  坂本毅治
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] 細胞・がん間質細胞特異的な酸素センシング機構を標的としたがん微小環境標的薬剤の開発2019
- Author(s)
  坂本毅治，福井優也，金森茜，村上善則，井上純一郎，清木元治
- Organizer
  第1回日本医学会連合「Rising Star」リトリート
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Host Mint3 controls chemotherapy-induced pre-metastatic niche formation2019
- Author(s)
  Takeharu Sakamoto, Yuya Fukui, Yoshinori Murakami, and Jun-ichiro Inoue
- Organizer
  Cell Symposia Hallmarks of Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] 腫瘍関連マクロファージにおけるHIF活性化因子Mint3の機能解析2019
- Author(s)
  福井優也，林哲郎，村上善則，井上純一郎，坂本毅治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] RNA exosome component EXOSC9 is indispensable for stress resistance in breast cancer.2019
- Author(s)
  Seiko Yoshino, Yuya Fukui, Yusuke Matsui, Motoharu Seiki, Yoshinori Murakami, Jun-ichiro Inoue, Takeharu Sakamoto
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] がん細胞の3-Dコラーゲンゲル増殖に関わる遺伝子のゲノムワイドshRNAスクリーニング2019
- Author(s)
  齊藤百合花，中岡寛樹，清木元治，村上善則，井上純一郎，坂本毅治
- Organizer
  第28回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] 宿主Mint3は化学療法による前転移ニッチ形成を促進する2019
- Author(s)
  坂本毅治，福井優也，原敏郎，金森茜，清木元治，村上善則，井上純一郎
- Organizer
  第28回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] Host Mint3 promotes chemotherapy-induced metastasis2019
- Author(s)
  坂本毅治，福井優也，清木元治，村上善則，井上純一郎
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] 生きた状態を反映したDrosophila視細胞の高圧凍結試料観察2019
- Author(s)
  齊藤百合花，寺田仁美，亀谷清和，坂口雅彦，坂本毅治，寺田信生
- Organizer
  第124回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Listeria monocytogenes感染におけるHIF-1活性化因子Mint3を介した自然免疫応答機構の解析2019
- Author(s)
  植松崇之，山﨑大賀，小林憲忠，井上純一郎，清木元治，坂本毅治
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07659
[Presentation] HIF 活性化分子 Mint3 によるがん微小環境制御機構の解明と創薬への応用2019
- Author(s)
  坂本毅治
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] 5.RNA exosome component EXOSC9 is indispensable for stress resistance in breast cancer.2019
- Author(s)
  Seiko Yoshino, Yuya Fukui, Yusuke Matsui, Motoharu Seiki, Yoshinori Murakami, Jun-ichiro Inoue, Takeharu Sakamoto
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] HIF 活性化分子 Mint3 によるがん微小環境制御機構の解明と創薬への応用2019
- Author(s)
  坂本毅治
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3を標的としたがん治療の可能性2018
- Author(s)
  坂本毅治，林哲郎，福井優也，鄭裕花，村上善則，清木元治
- Organizer
  第6回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 腫瘍関連マクロファージにおけるMint3の役割2018
- Author(s)
  坂本毅治
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] がん微小環境制御分子を標的としたがん治療の可能性2018
- Author(s)
  坂本毅治
- Organizer
  第1回がんと代謝研究会若手の会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 化学療法誘導性肺転移における宿主Mint3の役割2018
- Author(s)
  鄭裕花、村上善則、井上純一郎、坂本毅治
- Organizer
  先端モデル動物支援プラットフォーム若手支援技術講習会2018
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 肺腺がん細胞の実験的転移系を用いた転移関連分子の同定と機能解析2018
- Author(s)
  熊谷友紀，伊東剛，永田政義，川合剛人，坂本毅治，松原大祐，大場基，村上善則
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 天然変性タンパク質のフラグメント化によるタンパク質間相互作用阻害リガンド探索2018
- Author(s)
  長門石曉, 展天承, 坂本毅治, 清木元治, 津本浩平
- Organizer
  第12回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3はSKP2の転写を促進し膵癌細胞の細胞周期停止を抑制する2018
- Author(s)
  金森茜、村上善則、井上純一郎、坂本毅治
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 肺がん上皮間葉転換におけるアミノ酸代謝リプログラミング2018
- Author(s)
  中宿文絵、田畑祥、坂本毅治、平山明由、衣斐寛倫、山田忠明、矢野聖二、冨田勝、佐々木敦朗、曽我朋義
- Organizer
  第6回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 腫瘍関連マクロファージにおけるHIF活性化因子Mint3の機能解析2018
- Author(s)
  福井優也，林哲郎，村上善則，井上純一郎，坂本毅治
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 肺がん上皮間葉転換におけるアミノ酸代謝リプログラミング2018
- Author(s)
  中宿文絵、田畑祥、坂本毅治、平山明由、衣斐寛倫、山田忠明、矢野聖二、冨田勝、佐々木敦朗、曽我朋義
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] マウス正常組織におけるMunc-18 interacting protein 3 (Mint3) 局在の検討2018
- Author(s)
  齊藤百合花、鄭裕花、寺田信生、坂本毅治
- Organizer
  第59回日本組織細胞化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 化学療法誘導性肺転移における宿主Mint3の役割2018
- Author(s)
  鄭裕花，村上善則，井上純一郎，坂本毅治
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] がん細胞・間質細胞相互作用によるがん悪性化機構の解明2018
- Author(s)
  坂本毅治
- Organizer
  ROIS-DS-JOINT共同研究集会「若手カンファレンス：がん研究とデータサイエンスのコミュニケーション」
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] RNA exosome complex 9 (EXOSC9)はがん細胞のストレス耐性と造腫瘍能に必要である2018
- Author(s)
  坂本毅治，芳野聖子，福井優也，清木元治，村上善則，井上純一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3 Is a Novel Molecular Target Expressed in Well-Differentiated AFP-Negative HCC for Prevention of Cancer Progression2018
- Author(s)
  Masaki Nishitani, Taro Yamashita, Hikari Okada, Kouki Nio, Tsuyoshi Suda, Hajime Takatori, Masao Honda, Takeharu Sakamoto, Shuichi Kaneko
- Organizer
  the American Association for the Study of Liver Diseases (AASLD) The Liver Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 1.Mint3を標的としたがん治療の可能性2018
- Author(s)
  坂本毅治，林哲郎，福井優也，鄭裕花，村上善則，清木元治
- Organizer
  第6回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] 腫瘍関連マクロファージの分極化に関わる分子機構の解析2018
- Author(s)
  坂本毅治
- Organizer
  第27回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 腫瘍関連マクロファージにおけるMint3 の役割2018
- Author(s)
  坂本毅治，林哲郎，福井優也，村上善則
- Organizer
  平成29年度「先端モデル動物支援プラットフォーム成果発表会」
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 化学療法誘導性肺転移における宿主Mint3の役割2018
- Author(s)
  坂本毅治、福井優也、鄭裕花、村上善則、井上純一郎
- Organizer
  第16回がんとハイポキシア研究会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] インフルエンザウイルス感染におけるHIF-1活性化因子Mint3を介した自然免疫応答機構の解析2017
- Author(s)
  植松崇之、藤田智子、中岡寛樹、原敏朗、小林憲忠、村上善則、清木元治、坂本毅治
- Organizer
  第28回日本生体防御学会学術総会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] がん微小環境の制御に関わる分子機構の研究2017
- Author(s)
  坂本毅治
- Organizer
  第26回日本がん転移学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 腫瘍関連マクロファージにおけるMint3の役割2017
- Author(s)
  坂本毅治、林哲郎、福井優也、村上善則
- Organizer
  第15 回がんとハイポキシア研究会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 若手研究者から見たがん微小環境研究の展望2017
- Author(s)
  坂本毅治
- Organizer
  第76回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 腫瘍関連マクロファージにおけるHIF活性化因子Mint3の機能解析2017
- Author(s)
  林哲郎，福井優也，坂本毅治，村上善則
- Organizer
  先端モデル動物支援プラットフォーム「若手支援技術講習会2017」
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3は線維芽細胞においてL1CAM 発現を誘導することでインテグリンα5β1を介したがん細胞増殖と造腫瘍能を促進する2017
- Author(s)
  坂本毅治、清木元治
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] 腫瘍関連マクロファージにおけるHIF活性化因子Mint3の機能解析2017
- Author(s)
  林哲郎，福井優也，坂本毅治，村上善則
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 炎症性モノサイトにおけるAPBA3/Mint3はがん転移性ニッチ形成を制御する2017
- Author(s)
  坂本毅治、原敏朗、中岡寛樹、林哲郎、村上善則、清木元治
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] Mint3は線維芽細胞においてL1CAM 発現を誘導することでインテグリンα5β1を介したがん細胞増殖と造腫瘍能を促進する2017
- Author(s)
  坂本毅治，清木元治
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3は解糖系を介してがん転移性ニッチを形成する2017
- Author(s)
  坂本毅治
- Organizer
  第5回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] インフルエンザウイルス感染におけるHIF-1活性化因子Mint3を介した自然免疫応答機構の解析2017
- Author(s)
  植松崇之，藤田智子，中岡寛樹，原敏朗，小林憲忠，村上善則，清木元治，坂本毅治
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3は膵癌細胞の増殖を制御する2017
- Author(s)
  柳津瞳，金森茜，坂本毅治，村上善則，清木元治
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 膜型プロテアーゼMT1-MMPの非プロテアーゼ活性によるがん微小環境制御機構の解明2017
- Author(s)
  坂本毅治
- Organizer
  第76回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 炎症性モノサイトにおけるAPBA3/Mint3はがん転移性ニッチ形成を制御する2017
- Author(s)
  坂本毅治，原敏朗，中岡寛樹，林哲郎，村上善則，清木元治
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin α5β1 and tumour growth.2017
- Author(s)
  坂本毅治、中岡寛樹、種井善一、金森茜、林哲郎、清木元治、村上善則
- Organizer
  平成28年度文部科学省新学術領域研究　学術研究支援基盤形成　先端モデル動物支援プラットホーム成果発表会
- Place of Presentation
  琵琶湖ホテル（大津市）
- Year and Date
  2017-02-06
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 腫瘍関連マクロファージにおけるMint3の役割2017
- Author(s)
  坂本毅治、林哲郎、村上善則
- Organizer
  金沢大学がん進展制御研究共同利用・共同研究拠点シンポジウム・成果発表会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 天然変性蛋白質Mint3とFIH-1の相互作用機構の解明2017
- Author(s)
  展天承，中山佳昭，長門石暁，坂本毅治，清木元治，津本浩平
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3は線維芽細胞においてL1CAM 発現を誘導することでインテグリンα5β1を介したがん細胞増殖と造腫瘍能を促進する2017
- Author(s)
  坂本毅治、中岡寛樹、種井善一、金森茜、佐藤博、清木元治、村上善則
- Organizer
  金沢大学がん進展制御研究所共同利用・共同研究拠点シンポジウム
- Place of Presentation
  金沢東急ホテル（金沢市）
- Year and Date
  2017-02-14
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes2017
- Author(s)
  Takeharu Sakamoto
- Organizer
  7th International Conference on Tumor-Host Interaction and Angiogenesis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3は膵癌細胞の細胞増殖を制御する2017
- Author(s)
  金森茜，中岡寛樹，林哲郎，村上善則，坂本毅治
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 線維芽細胞との接着を介したがん細胞の増殖機構2016
- Author(s)
  坂本毅治、中岡寛樹、金森茜、清木元治、村上善則
- Organizer
  平成27年度「がん研究分野の特性等を踏まえた支援活動」個体レベルでのがん研究支援活動ワークショップ
- Place of Presentation
  琵琶湖ホテル（滋賀県大津市）
- Year and Date
  2016-02-04
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] ERKシグナル標的分子RNF126はミトコンドリアへの代謝フラックスを変えることでアノイキス抵抗性を制御する2016
- Author(s)
  坂本毅治、芳野聖、中岡寛樹、金森茜、清木元治、村上善則
- Organizer
  日本がん学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes2016
- Author(s)
  Toshiro Hara, Hiroki J. Nakaoka, Kouhei Mimura, Daisuke Hoshino, Masahiro Inoue, Fumitaka Nagamura, Yoshinori Murakami, Motoharu Seiki, and Takeharu Sakamoto
- Organizer
  Tenth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Hyatt Regency Maui (Maui, HI, USA)
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 線維芽細胞との接着を介したがん細胞の増殖機構2016
- Author(s)
  坂本毅治、中岡寛樹、金森茜、清木元治、村上善則
- Organizer
  平成27年度「がん研究分野の特性等を踏まえた支援活動」個体レベルでのがん研究支援活動ワークショップ
- Place of Presentation
  琶湖ホテル（滋賀県大津市）
- Year and Date
  2016-02-04
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 線維芽細胞におけるMint3は腫瘍増殖を促進する2016
- Author(s)
  中岡寛樹、金森茜、清木元治、村上善則、坂本毅治
- Organizer
  日本がん学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes2016
- Author(s)
  Toshiro Hara, Hiroki J. Nakaoka, Kouhei Mimura, Daisuke Hoshino, Masahiro Inoue, Fumitaka Nagamura, Yoshinori Murakami, Motoharu Seiki, and Takeharu Sakamoto
- Organizer
  Tenth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Hyatt Regency Maui (Maui, HI, USA)
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] ERKシグナル標的分子RNF126はミトコンドリアへの代謝フラックスを変えることでアノイキス抵抗性を制御する2016
- Author(s)
  坂本毅治、芳野聖子、中岡寛樹、金森茜、清木元治、村上善則
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 線維芽細胞におけるMint3は腫瘍増殖を促進する2016
- Author(s)
  中岡寛樹、金森茜、清木元治、村上善則、坂本毅治
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3を標的としたがん微小環境の制御2016
- Author(s)
  坂本毅治、清木元治
- Organizer
  第20回日本がん分子標的治療学会学術集会
- Place of Presentation
  別府国際コンベンションセンター（別府市）
- Year and Date
  2016-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] RNF126はミトコンドリアへの代謝フラックスを変化させることでがん細胞のアノイキス耐性を制御する2016
- Author(s)
  坂本毅治、清木元治
- Organizer
  第25回日本がん転移学会学術集会・総会
- Place of Presentation
  米子コンベンションセンター（米子市）
- Year and Date
  2016-07-21
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] がんおよび炎症性疾患におけるHIF活性化分子Mint3の役割2016
- Author(s)
  坂本毅治、原敏朗、中岡寛樹、金森茜、清木元治、村上善則
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] ERKシグナル標的分子RNF126はミトコンドリアへの代謝フラックスを変えることでがんのアノイキス耐性を制御する2016
- Author(s)
  坂本毅治、芳野聖子、原敏朗、中岡寛樹、金森茜、清木元治、村上善則
- Organizer
  文部科学省新学術領域研究　学術研究支援基盤形成　先端モデル動物支援プラットフォーム　若手支援技術講習会
- Place of Presentation
  蓼科グランドホテル滝の湯（茅野市）
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3は線維芽細胞においてL1CAM 発現を誘導することでインテグリンα5β1を介したがん細胞増殖と造腫瘍能を促進する2016
- Author(s)
  坂本毅治、中岡寛樹、種井善一、金森茜、清木元治、村上善則
- Organizer
  第14回がんとハイポキシア研究会
- Place of Presentation
  岐阜グランドホテル（岐阜市）
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 水酸化シグナルによる低酸素応答とその制御2016
- Author(s)
  坂本毅治
- Organizer
  第16回日本抗加齢医学会総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-06-10
- Invited
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 線維芽細胞におけるMint3がHIF-1を介してがん細胞の増殖を促進する2016
- Author(s)
  坂本毅治
- Organizer
  第4回低酸素研究会
- Place of Presentation
  早稲田大学（新宿区）
- Year and Date
  2016-07-23
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3は炎症性モノサイトの解糖系とVEGF産生を介して転移ニッチ形成を制御する2015
- Author(s)
  坂本毅治、原敏朗、中岡寛樹、清木元治、村上善則
- Organizer
  第3回がんと代謝研究会
- Place of Presentation
  石川県立音楽堂交流ホール（石川県金沢市）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] NECAB3 Maintains Enhanced Glycolysis and Tumorigenicity in Cancer Cells2015
- Author(s)
  Hiroki J. Nakaoka, Seiko Yoshino, Motoharu Seiki, Yoshinori Murakami, and Takeharu Sakamoto
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 新規HIF活性化分子Mint3は単球・マクロファージにおいてがん転移を促進する2015
- Author(s)
  中岡　寛樹、原　敏朗、清木　元治、村上　善則、坂本　毅治
- Organizer
  がん若手研究者ワークショップ
- Place of Presentation
  蓼科グランドホテル滝の湯（長野県茅野市）
- Year and Date
  2015-09-03
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Roles of MT1-MMP in cancer malignancy: invasion, metabolism, and more!2015
- Author(s)
  Takeharu Sakamoto
- Organizer
  第24回日本がん転移学会学術集会・総会
- Place of Presentation
  シティプラザ大阪（大阪府大阪市）
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] NECAB3 Maintains Enhanced Glycolysis and Tumorigenicity in Cancer Cells.2015
- Author(s)
  Hiroki J. Nakaoka, Seiko Yoshino, Motoharu Seiki, Yoshinori Murakami, and Takeharu Sakamoto
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.2015
- Author(s)
  Takeharu Sakamoto, Toshiro Hara, Hiroki J. Nakaoka, Yoshinori Murakami, Motoharu Seiki.
- Organizer
  the 3rd Conference of the Japanese Association for Hypoxia Biology
- Place of Presentation
  早稲田大学（東京都新宿区）
- Year and Date
  2015-07-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] RNA exosome component, EXOSC9, regulates the number of cytoplasmic processing bodies in mammalian cells.2015
- Author(s)
  Yoshino S, Murakami Y, Seiki M, Sakamoto T.
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] ユビキチンリガーゼRNF126の新規基質の探索2015
- Author(s)
  三隅　匡也、中岡　寛樹、芳野　聖子、清木　元治、村上　善則、坂本　毅治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] RNF126はミトコンドリアへの代謝フラックスを制御し、がん細胞の足場非依存的増殖を促進する2015
- Author(s)
  芳野聖子、中岡寛樹、金森茜、清木元治、村上善則、坂本毅治
- Organizer
  第３回がんと代謝研究会
- Place of Presentation
  石川県立音楽堂交流ホール（石川県金沢市）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.2015
- Author(s)
  Takeharu Sakamoto, Toshiro Hara, Hiroki J. Nakaoka, Yoshinori Murakami, Motoharu Seiki
- Organizer
  the 3rd Conference of the Japanese Association for Hypoxia Biology
- Place of Presentation
  早稲田大学（東京都新宿区）
- Year and Date
  2015-07-26
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] RNF126 supports anchorage-independent cancer growth via regulation of metabolic flux to mitochondria.2015
- Author(s)
  Yoshino S, Nakaoka H, Kanamori A, Seiki M, Murakami Y, Sakamoto T.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 炎症性モノサイトにおけるAPBA3/Mint3を標的とした転移ニッチ形成の制御2015
- Author(s)
  坂本　毅治、中岡　寛樹、清木　元治、村上　善則
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3 controls pancreas cancer cell proliferation2015
- Author(s)
  阿蘇友佳里、金森茜、芳野聖子、深見希代子、村上善則、坂本毅治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 線維芽細胞におけるMint3 のがん悪性化における役割2015
- Author(s)
  坂本毅治、中岡寛樹、清木元治、村上善則
- Organizer
  第13 回がんとハイポキシア研究会
- Place of Presentation
  国立遺伝学研究所（静岡県三島市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3 controls pancreas cancer cell proliferation2015
- Author(s)
  阿蘇友佳里、金森茜、芳野聖子、深見希代子、村上善則、坂本毅治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] RNF126はミトコンドリアへの代謝フラックスを制御し、がん細胞の足場非依存的増殖を促進する2015
- Author(s)
  芳野聖子、中岡寛樹、金森茜、清木元治、村上善則、坂本毅治
- Organizer
  第３回がんと代謝研究会
- Place of Presentation
  石川県立音楽堂交流ホール（石川県金沢市）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 炎症性モノサイトにおけるMint3を標的とした転移性ニッチ形成の制御2015
- Author(s)
  坂本毅治、清木元治
- Organizer
  第19回日本がん分子標的治療学会学術集会
- Place of Presentation
  松山全日空ホテル（愛媛県松山市）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] RNF126はミトコンドリアへの代謝フラックスの制御を介してがん細胞の足場非依存的な増殖を補助する2015
- Author(s)
  坂本毅治、芳野聖子、原敏朗、中岡寛樹、 金森茜、村上善則、清木元治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 炎症性モノサイトにおけるAPBA3/Mint3を標的とした転移ニッチ形成の制御2015
- Author(s)
  坂本　毅治、中岡　寛樹、清木　元治、村上　善則
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 線維芽細胞におけるMint3 のがん悪性化における役割2015
- Author(s)
  坂本毅治、中岡寛樹、清木元治、村上善則
- Organizer
  第13 回がんとハイポキシア研究会
- Place of Presentation
  国立遺伝学研究所（静岡県三島市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 炎症性モノサイトにおけるMint3を標的とした転移性ニッチの制御2015
- Author(s)
  原敏朗、中岡寛樹、清木元治、村上善則、坂本毅治
- Organizer
  第33回日本ヒト細胞学会学術集会
- Place of Presentation
  ホテルスカイタワー（宮崎県宮崎市）
- Year and Date
  2015-08-22
- Invited
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes2015
- Author(s)
  Hiroki J. Nakaoka, Toshiro Hara, Motoharu Seiki, Yoshinori Murakami, Takeharu Sakamoto
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 炎症性モノサイトにおけるMint3を標的とした転移性ニッチの制御2015
- Author(s)
  坂本　毅治、原　敏朗、中岡　寛樹、村上善則、清木　元治
- Organizer
  日本癌学会シンポジウム
- Place of Presentation
  石川県立音楽堂交流ホール（石川県金沢市）
- Year and Date
  2015-01-21
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 新規HIF活性化分子Mint3は単球・マクロファージにおいてがん転移を促進する2015
- Author(s)
  中岡　寛樹、原　敏朗、清木　元治、村上　善則、坂本　毅治
- Organizer
  がん若手研究者ワークショップ
- Place of Presentation
  蓼科グランドホテル滝の湯（長野県茅野市）
- Year and Date
  2015-09-03
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 炎症性モノサイトにおけるMint3を標的とした転移性ニッチ形成の制御2015
- Author(s)
  坂本毅治、清木元治
- Organizer
  第19回日本がん分子標的治療学会学術集会
- Place of Presentation
  松山全日空ホテル（愛媛県松山市）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] 炎症性モノサイトにおけるMint3を標的とした転移性ニッチの制御2015
- Author(s)
  原敏朗、中岡寛樹、清木元治、村上善則、坂本毅治
- Organizer
  第33回日本ヒト細胞学会学術集会
- Place of Presentation
  ホテルスカイタワー（宮崎県宮崎市）
- Year and Date
  2015-08-22
- Invited
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Roles of MT1-MMP in cancer malignancy: invasion, metabolism, and more!2015
- Author(s)
  Takeharu Sakamoto
- Organizer
  第24回日本がん転移学会学術集会・総会
- Place of Presentation
  シティプラザ大阪（大阪府大阪市）
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 炎症性モノサイトにおけるMint3を標的とした転移性ニッチ形成の制御2015
- Author(s)
  坂本毅治、清木元治
- Organizer
  第24回日本がん転移学会学術集会・総会
- Place of Presentation
  シティプラザ大阪（大阪府大阪市）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] ユビキチンリガーゼRNF126の新規基質の探索2015
- Author(s)
  三隅　匡也、中岡　寛樹、芳野　聖子、清木　元治、村上　善則、坂本　毅治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] RNF126はミトコンドリアへの代謝フラックスの制御を介してがん細胞の足場非依存的な増殖を補助する2015
- Author(s)
  坂本毅治、芳野聖子、原敏朗、中岡寛樹、 金森茜、村上善則、清木元治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Control of metastatic niche formation by targeting Mint3 in inflammatory monocytes2015
- Author(s)
  Takeharu Sakamoto, Toshiro Hara, Hiroki J. Nakaoka, Yoshinori Murakami, Motoharu Seiki
- Organizer
  平成26年度「個体レベルでのがん研究支援活動」ワークショップ
- Place of Presentation
  琵琶湖ホテル（滋賀県大津市）
- Year and Date
  2015-02-06
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] RNF126 supports anchorage-independent cancer growth via regulation of metabolic flux to mitochondria.2015
- Author(s)
  Yoshino S, Nakaoka H, Kanamori A, Seiki M, Murakami Y, Sakamoto T.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] Mint3は炎症性モノサイトの解糖系とVEGF産生を介して転移ニッチ形成を制御する2015
- Author(s)
  坂本毅治、原敏朗、中岡寛樹、清木元治、村上善則
- Organizer
  第３回がんと代謝研究会
- Place of Presentation
  石川県立音楽堂交流ホール（石川県金沢市）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K06829
[Presentation] RNA exosome component, EXOSC9, regulates the number of cytoplasmic processing bodies in mammalian cells2015
- Author(s)
  Yoshino S, Murakami Y, Seiki M, Sakamoto T.
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes2015
- Author(s)
  Hiroki J. Nakaoka, Toshiro Hara, Motoharu Seiki, Yoshinori Murakami, Takeharu Sakamoto
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 炎症性モノサイトにおけるMint3を標的とした転移性ニッチ形成の制御2015
- Author(s)
  坂本毅治、清木元治
- Organizer
  第24回日本がん転移学会学術集会・総会
- Place of Presentation
  シティプラザ大阪（大阪府大阪市）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Mint3 in monocytes/macrophages promotes cancer metastasis2014
- Author(s)
  Takeharu Sakamoto, Toshiro Hara, Hiroki J. Nakaoka, Motoharu Seiki
- Organizer
  15th International Biennial Congress Metastasis Research Society
- Place of Presentation
  Heidelberg (Germany)
- Year and Date
  2014-06-30
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] mTORとMT1-MMPのクロストークを介したHIF-1の制御2014
- Author(s)
  坂本　毅治、清木　元治
- Organizer
  文部科学省新学術領域・がん支援「化学療法基盤支援活動」第3 回シンポジウム
- Place of Presentation
  万国津梁館（沖縄県名護市）
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Mint3 is a possible target for cancer therapy by regulating the tumor microenvironment2014
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] E3リガーゼRNF126はTCAサイクルへの代謝フラックスと腫瘍増殖を制御する2014
- Author(s)
  芳野　聖子、清木　元治、坂本　毅治
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 炎症性モノサイトにおけるMint3 を標的とした転移性ニッチの制御2014
- Author(s)
  坂本　毅治、原　敏朗、中岡　寛樹、清木　元治
- Organizer
  第12回がんとハイポキシア研究会
- Place of Presentation
  ホテルマリターレ創世佐賀（佐賀県佐賀市）
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Role of the novel HIF activator Mint3 in macrophages2014
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki, Yoshinori Murakami
- Organizer
  China-Japan Join Laboratory Workshop 2014
- Place of Presentation
  Beijing (China)
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] HIF活性化分子・Mint3による炎症性モノサイトの機能制御ががん転移を促進する2014
- Author(s)
  坂本　毅治、原　敏朗、中岡　寛樹、清木　元治
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Mint3による炎症性モノサイトの遊走制御がE-selectin発現誘導を介して転移を成立させる2014
- Author(s)
  坂本　毅治、清木　元治
- Organizer
  第23回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール・金沢ニューグランドホテル（石川県金沢市）
- Year and Date
  2014-07-10
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 新規HIF活性化分子Mint3のマクロファージでのがん悪性化における役割2013
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] MT1-MMP/Mint3を介した mTORによるHIF-1活性化2013
- Author(s)
  坂本毅治、清木元治
- Organizer
  第1回がんと代謝研究会
- Place of Presentation
  鶴岡
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Mint3 promotes tumor malignancy in cancer and stromal cells2013
- Author(s)
  Takeharu Sakamoto, Toshiro Hara, Motoharu Seiki
- Organizer
  Ninth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Maui, HI, USA
- Invited
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 新規HIF活性化分子Mint3のマクロファージでのがん悪性化における役割2013
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第22回日本がん転移学会学術集会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] 新規 HIF 活性化分子Mint3 は単球・マクロファージにおいてがん転移を促進する2013
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第11 回がんとハイポキシア研究会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Mint3 promotes tumor malignancy in cancer and stromal cells2013
- Author(s)
  Sakamoto,T. Hara,T., and Seiki,M
- Organizer
  Ninth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  USA, Maui
- Invited
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] 新規HIF活性化分子Mint3のマクロファージでのがん悪性化における役割2013
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] 新規HIF活性化分子Mint3のマクロファージでのがん悪性化における役割2013
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第22回日本がん転移学会学術集会・総会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 新規ユビキチンリガーゼRNF126は通常酸素下で代謝バランスを調節し、腫瘍増殖を制御する2013
- Author(s)
  芳野聖子、坂本毅治、清木元治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] マクロファージにおけるMint3 はがん転移を促進する2013
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] 新規HIF 活性化分子Mint3は単球・マクロファージにおいてがん転移を促進する2013
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] 新規HIF 活性化分子Mint3は単球・マクロファージにおいてがん転移を促進する2013
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Mint3 promotes tumor malignancy in cancer and stromal cells2013
- Author(s)
  Takeharu Sakamoto, Toshiro Hara, Motoharu Seiki
- Organizer
  Ninth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Maui, HI, USA
- Invited
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] マクロファージにおけるMint3 はがん転移を促進する2013
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] A novel E3 ligase, RNF126, regulates the metabolic fate of pyrubate during normoxia and tumor growth2012
- Author(s)
  Seiko Yoshino, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Mint3 is a new molecular target for metastasis suppression2012
- Author(s)
  Sakamoto T, Seiki M.
- Organizer
  The 16th JFCR-ISCC
- Place of Presentation
  東京
- Year and Date
  2012-01-25
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Deletion of the Mint3 Gene in Mice Abrogates Macrophage Functions and Increases Resistance to Cancer Metastasis2012
- Author(s)
  原敏朗、坂本毅治、清木元治
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] 新規HIF活性化因子・Mint3の生体における機能の解析2012
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Mint3 is a new molecular target for metastasis suppression2012
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  The 16th JFCR-ISCC
- Place of Presentation
  東京
- Year and Date
  2012-01-25
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Mint3 promotes tumor malignancy in cancer and stromal cells2012
- Author(s)
  Sakamoto,T., Hara,T., and Seiki, M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Mint3 is a new molecular target for metastasis suppression2012
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  The 16th JFCR-ISCC
- Place of Presentation
  東京
- Year and Date
  2012-01-25
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3 deficiency abrogates macrophage functios and suppresses tumor metastasis2012
- Author(s)
  Toshiro Hara, Kohei Mimura, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Deletion of the Mint3 Gene in Mice Abrogates Macrophage Functions and Increases Resistance to Cancer Metastasis2012
- Author(s)
  原敏朗、坂本毅治、清木元治
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] The analysis of stromal Mint3 that promotes tumor malignancy2012
- Author(s)
  Jane Weng, Toshiro Hara, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] The analysis of stromal Mint3 that promotes tumor malignancy2012
- Author(s)
  Jane Weng, Toshiro Hara, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Crosstalk between mTOR and MT1-MMP via Mint3 Induces Post-translational Activation of HIF-12012
- Author(s)
  坂本毅治、Weng Jane, 原敏朗、芳野聖子、清木元治
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] 新規HIF活性化因子・Mint3の生体における機能の解析2012
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第85回日本生化学会総会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] 新規HIF活性化因子・Mint3の生体における機能の解析2012
- Author(s)
  坂本　毅治、原　敏朗、清木　元治
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Mint3 promotes tumor malignancy in cancer and stromal cells2012
- Author(s)
  Takeharu Sakamoto, Toshiro Hara, Motoharu Seiki
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Mint3 deficiency abrogates macrophage functios and suppresses tumor metastasis2012
- Author(s)
  Toshiro Hara, Kohei Mimura, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] A novel E3 ligase, RNF126, regulates the metabolic fate of pyrubate during normoxia and tumor growth2012
- Author(s)
  Seiko Yoshino, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Mint3 promotes tumor malignancy in cancer and stromal cells2012
- Author(s)
  Takeharu Sakamoto, Toshiro Hara, Motoharu Seiki
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Crosstalk between mTOR and MT1-MMP via Mint3 Induces Post-translational Activation of HIF-12012
- Author(s)
  坂本毅治、Weng Jane, 原敏朗、芳野聖子、清木元治
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24591313
[Presentation] Deletion of the Mint3 gene in mice abrogates macrophage functions and increases resistance to cancer metastasis2011
- Author(s)
  原敏朗、三村耕平、坂本毅治、清木元治
- Organizer
  平成23年度がん若手研究者ワークショップ
- Place of Presentation
  長野
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Ubiquitin ligase RNF126 serves as a gate keeper from glycolysis to oxidative phosphorylation and regulates tumor growth2011
- Author(s)
  Yoshino S, Sakamoto T Seiki M.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Deletion of the Mint3/Apba3 Gene in Mice Abrogates Macrophage Functions and Increases Resistance to Lipopolysaccharide-induced Septic Shock2011
- Author(s)
  Toshiro Hara, Kouhei Mimura, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] MT1-MMP/Mint3は通常酸素下でHIF-1を活性化しマクロファージおよび癌細胞の解糖系を亢進させる2011
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  日本がん分子標的治療学会第15回学術集会
- Place of Presentation
  東京
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Deletion of the Mint3/Apba3 Gene in Mice Abrogates Macrophage Functions and Increases Resistance to Lipopolysaccharide-induced Septic Shock.2011
- Author(s)
  Hara T Mimura K, Hara T, Sakamoto T, Seiki M.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloprotease2011
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] MT1-MMP/Mint3は通常酸素下でHIF-1を活性化しマクロファージおよび癌細胞の解糖系を亢進させる2011
- Author(s)
  Sakamoto T, Seiki M.
- Organizer
  日本がん分子標的治療学会第15回学術集会
- Place of Presentation
  東京
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Mint3 in tumor stromal cells promotes tumor metastasis2011
- Author(s)
  Kouhei Mimura, Toshiro Hara, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Analysis of the regulatory mechanism of HIF-1 activation by Mint3 during normoxia2011
- Author(s)
  Jane S.Weng, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloprotease2011
- Author(s)
  Sakamoto T, Seiki M.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloprotease2011
- Author(s)
  Sakamoto T, Seiki M.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloprotease2011
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloprotease2011
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Analysis of the regulatory mechanism of HIF-1 activation by Mint3 during normoxia2011
- Author(s)
  Jane S.Weng, Takeharu Sakamoto Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Mint3 in tumor stromal cells promotes tumor metastasis2011
- Author(s)
  Mimura K, Hara T, Sakamoto T, Seiki M.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Mint3/APBA3 regulating HIF-1 activation in macrophages play a critical role in LPS-induced septic shock in a mouse model2011
- Author(s)
  Toshiro Hara, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Mint3 in tumor stromal cells promotes tumor metastasis2011
- Author(s)
  Mimura K, Hara T, Sakamoto T, Seiki M.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Deletion of the Mint3 gene in mice abrogates macrophage functions and increases resistance to cancer metastasis2011
- Author(s)
  原敏朗、三村耕平、坂本毅治、清木元治
- Organizer
  平成23年度がん若手研究者ワークショップ
- Place of Presentation
  長野
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Deletion of the Mint3/Apba3 Gene in Mice Abrogates Macrophage Functions and Increases Resistance to Lipopolysaccharide-induced Septic Shock2011
- Author(s)
  Toshiro Hara, Kouhei Mimura, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] MT1-MMP/Mint3は通常酸素下でHIF-1を活性化しマクロファージおよび癌細胞の解糖系を亢進させる2011
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  日本がん分子標的治療学会第15回学術集会
- Place of Presentation
  東京
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Analysis of the regulatory mechanism of HIF-1 activation by Mint3 during normoxia2011
- Author(s)
  Jane S.Weng, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Ring finger protein 126, RNF126, is a new E3 ubiquitin ligase that serves as a gate keeper from glycolysis to oxidative phosphorylation and regulates tumor growth2011
- Author(s)
  芳野聖子、坂本毅治、清木元治
- Organizer
  平成23年度がん若手研究者ワークショップ
- Place of Presentation
  長野
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3 in tumor stromal cells promotes tumor metastasis2011
- Author(s)
  Kouhei Mimura, Toshiro Hara, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] ZF21, a novel focal adhesion-related protein, promotes cancer cell invasion2011
- Author(s)
  Nagano M, Hoshino D, Sakamoto T, Okihara R, Konishi M, Ko-shikawa N, Akizawa T, Seiki M
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Analysis of the regulatory mechanism of HIF-1 activation by Mint3 during normoxia2011
- Author(s)
  Jane S.Weng, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Ubiquitin ligase RNF126 serves as a gate keeper from glycolysis to oxidative phosphorylation and regulates tumor growth2011
- Author(s)
  Seiko Yoshino, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Ubiquitin ligase RNF126 serves as a gate keeper from glycolysis to oxidative phosphorylation and regulates tumor growth2011
- Author(s)
  Seiko Yoshino, Sakamoto T Seiki M.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Ubiquitin ligase RNF126 serves as a gate keeper from glycolysis to oxidative phosphorylation and regulates tumor growth2011
- Author(s)
  Seiko Yoshino, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] ZF21, a novel focal adhesion-related protein, promotes cancer cell invasion2011
- Author(s)
  Makoto Nagano, Daisuke Hoshino, Takeharu Sakamoto, Rika Okihara, Motomi Konishi, Naohiko Koshikawa, Toshifumi Akizawa, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Ring finger protein 126, RNF126, is a new E3 ubiquitin ligase that serves as a gate keeper from glycolysis to oxidative phosphorylation and regulates tumor growth2011
- Author(s)
  芳野聖子、坂本毅治、清木元治
- Organizer
  平成23年度がん若手研究者ワークショップ
- Place of Presentation
  長野
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloprotease2011
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloprotease2011
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3 in tumor stromal cells promotes tumor metastasis2011
- Author(s)
  Kouhei Mimura, Toshiro Hara, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Ring finger protein 126, RNF126, is a new E3 ubiquitin ligase that serves as a gate keeper from glycolysis to oxidative phosphorylation and regulates tumor growth2011
- Author(s)
  芳野聖子、坂本毅治、清木元治
- Organizer
  平成23年度がん若手研究者ワークショップ
- Place of Presentation
  長野
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Ubiquitin ligase RNF126 serves as a gate keeper from glycolysis to oxidative phosphorylation and regulates tumor growth2011
- Author(s)
  Seiko Yoshino, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Mint3 in tumor stromal cells promotes tumor metastasis2011
- Author(s)
  Kouhei Mimura, Toshiro Hara, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Targeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloprotease2011
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] ZF21, a novel focal adhesion-related protein, promotes cancer cell invasion2011
- Author(s)
  Makoto Nagano, Daisuke Hoshino, Takeharu Sakamoto, Rika Okihara, Motomi Konishi, Naohiko Koshikawa, Toshifumi Akizawa, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Ubiquitin ligase RNF126 serves as a gate keeper from glycolysis to oxidative phosphorylation and regulates tumor growth2011
- Author(s)
  Seiko Yoshino, Takeharu Sakamoto Motoharu Seiki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PUBLICLY-23112505
[Presentation] Analysis of the regulatory mechanism of HIF-1 activation by Mint3 during normoxia2011
- Author(s)
  Jane S. Weng, Sakamoto T, Seiki M.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Deletion of the Mint3 gene in mice abrogates macrophage functions and increases resistance to cancer metastasis2011
- Author(s)
  原敏朗、三村耕平、坂本毅治、清木元治
- Organizer
  平成23年度がん若手研究者ワークショップ
- Place of Presentation
  長野
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3/APBA3 regulating HIF-1 activation in macrophages play a critical role in LPS-induced septic shock in a mouse model2011
- Author(s)
  Toshiro Hara, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Analysis of the regulatory mechanism of HIF-1 activation by Mint3 during normoxia2011
- Author(s)
  Jane S. Weng, Sakamoto T, Seiki M.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Mint3/APBA3 regulating HIF-1 activation in macrophages play a critical role in LPS-induced septic shock in a mouse model2011
- Author(s)
  Hara T, Hara T, Sakamoto T, Seiki M.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] A membrane protease regulates energy production in macrophages by activating Hypoxia-Inducible Factor-1 via a non-proteolytic mechanism2010
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第69回日本癌学会学術会議
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] A novel FIH-1 suppresser, Mint3 regulates macrophage functions in vitro and in vivo2010
- Author(s)
  原敏朗、坂本毅治、清木元治
- Organizer
  第19回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3 enhances the activity of HIF-1 in macrophages by suppressing the activity of FIH-12010
- Author(s)
  Takeharu Sakamoto and Motoharu Seiki
- Organizer
  第19回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3 enhances the activity of HIF-1 in macrophages by suppressing the activity of FIH-12010
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  18th International Symposium on Molecular Cell Biology of Macrophages 2010
- Place of Presentation
  Kumamoto Parea Hall, Kumamoto, Japan
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3 regulates macrophage functions in vitro and in vivo by suppressing FIH-12010
- Author(s)
  Toshiro Hara, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] MT1-MMP/Mint3 axis augments glycolysis in macrophages and cancer cells2010
- Author(s)
  Takeharu Sakamoto and Motoharu Seiki
- Organizer
  「がん研究分野の特性等を踏まえた支援活動」がん若手ワークショップ
- Place of Presentation
  蓼科
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3 enhances the activity of HIF-1 in macrophages by suppressing the activity of FIH-12010
- Author(s)
  Takeharu Sakamoto and Motoharu Seiki
- Organizer
  18th International Symposium on Molecular Cell Biology of Macrophages
- Place of Presentation
  熊本
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3 enhances the activity of HIF-1 in macrophages by suppressing the activity of FIH-12010
- Author(s)
  坂本毅治、清木元治
- Organizer
  第19回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール(金沢市)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] A membrane protease regulates energy production in macrophages by activating Hypoxia-Inducible Factor-1 via a non-proteolytic mechanism2010
- Author(s)
  Takeharu Sakamoto and Motoharu Seiki
- Organizer
  第69回日本癌学会学術会議
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] A membrane protease regulates energy production in macrophages by activating Hypoxia-Inducible Factor-1 via a non-proteolytic mechanism2010
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] A membrane protease regulates energy production in macrophages by activating Hypoxia-Inducible Factor-1 via a non-proteolytic mechanism2010
- Author(s)
  Takeharu Sakamoto and Motoharu Seiki
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] MT1-MMP/Mint3 axis augments glycolysis in macrophages and cancer cells2010
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  「がん研究分野の特性等を踏まえた支援活動」がん若手ワークショップ
- Place of Presentation
  アートランドホテル蓼科
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3 enhances the activity of HIF-1 in macrophages by suppressing the activity of FIH-12010
- Author(s)
  Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第19回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Idenitification of novel genes that mediate hypoxic adaptation using a genome-wide siRNA screening in cancer cells2010
- Author(s)
  Seiko Yoshino, Takeharu Sakamoto, Motoharu Seiki
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] ゲノムワイドsiRNAライブラリーを用いた新規低酸素適応因子の同定2010
- Author(s)
  芳野聖子、坂本毅治、清木元治
- Organizer
  第69回日本癌学会学術会議
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] MT1-MMPはプロテアーゼ活性非依存的にHIF-1を活性化しマクロファージのエネルギー産生を制御する2010
- Author(s)
  坂本毅治、清木元治
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] ゲノムワイドsiRNAライブラリーを用いた新規低酸素適応因子の同定2010
- Author(s)
  芳野聖子、坂本毅治、清木元治
- Organizer
  第19回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22790846
[Presentation] Mint3 enhances the activity of hypoxia inducible factor-1 in macrophages by suppressing the activity of factor inhibiting HIF-12010
- Author(s)
  Sakamoto, T. and Seiki,M
- Organizer
  8th Joint Conference of the American Association for Cancer Research and Japanese Cancer Association
- Place of Presentation
  Waikoloa, Hawai, U.S.A
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] MT1-MMP/Mint3を介した mTORによるHIF-1活性化
- Author(s)
  坂本毅治、清木元治
- Organizer
  第1回がんと代謝研究会
- Place of Presentation
  鶴岡
- Data Source
  KAKENHI-PROJECT-22220014
[]

1. SEIKI Motoharu (10154634)

# of Collaborated Projects: 2 results

# of Collaborated Products: 48 results
2. KOSHIKAWA Naohiko (70334282)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. FUKADA Satoshi (80527599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HOSHINO Daisuke (30571434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. SYUUO Takuya (90399006)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAGANO Makoto (50572715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. Goyama Susumu (80431849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 滝野隆久 (40322119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 金子周一 (60185923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山下太郎 (90377432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 久松雄一 (10529861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 三森功士 (50322748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 胡慶江 (80792902)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田畑祥 (30708342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 曽我朋義 (60338217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 齊藤朋人 (10548605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 石田光明 (00464173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 林美樹夫 (10368251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 赤間智也 (10548788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 田中伯享 (30815882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. 城村由和 (40616322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MATSYBARA Daisuk

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. TSUCHIYA Kohsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 齊藤百合花

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
25. 村上善則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 伊東剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 西岡安彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKAMOTO TAKEHARU 坂本 毅治

SAKAMOTO Takeharu 坂本 毅治

Research Projects

Research Products

Co-Researchers

Elucidating mechanism of high-grade malignancy of lung adenocarcinoma focusing on carbohydrate antigen MECA-79

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

空間的シングルセル解析による大腸腺腫から発がん過程に於ける免疫寛容獲得機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がん治療薬誘導性間質細胞老化の分子病態の解明と治療応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

大腸がんにおけるオンコメタボライト・L-2HGの分子基盤の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

転移時のがんー間質相互作用を標識するin vivo ケミカルラベリング法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring novel mechanisms of chemotherapy-induced metastasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Crosstalk between clonal hematopoiesis and solid tumors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of MT1-MMP-dependent molecular pathways in the diversity and transformation of hepatocellular carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of anchorage-independent growth regulation in tumor progressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive screening of glycolysis-related genes by synthetic lethalityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

がん組織における高―中酸素分圧下での新規ＨＩＦ活性化メカニズムの機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of MT1-MMP in cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploring novel genes that regulate glycolysis using a genome-wide siRNA libraryPrincipal Investigator

Principal Investigator

Project Period (FY)

SAKAMOTO TAKEHARU 坂本毅治

SAKAMOTO Takeharu 坂本毅治

[Book] 医学のあゆみ第271巻9号「がん細胞・がん間質細胞特異的な酸素センシング機構を標的としたがん微小環境標的薬剤の開発」2019

[Book] THE LUNG perspectives vol.23 No.3　「MT1-MMP/Mint3によるHIF-1活性化メカニズム」2015

[Book] THE LUNG perspectives　「MT1-MMP/Mint3によるHIF-1活性化メカニズム」2015

[Book] 南山堂：「次世代がん戦略研究updateがん基盤生物学－革新的シーズ育成に向けて－」、「13. MT1-MMP及び周辺分子を標的としたがん組織制御薬剤の開発」2013

[Book] がんの浸潤・転移第20章細胞外マトリックス(ECM)2011