Fujieda Yuichiro 藤枝雄一郎

Researcher Number	70790872
Other IDs	https://orcid.org/0000-0003-4705-341X
Affiliation (Current)	2024: 北海道大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2017 – 2023: 北海道大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator 抗リン脂質抗体症候群 / プロトロンビン / 抗原提示 / 抗リン脂質抗体 / ミクログリア / 機能的核磁気共鳴画像 / 慢性疼痛 / 慢性炎症 / 全身性エリテマトーデス / ミスフォールドタンパク … More / 単球 / 免疫学 / 内科 / 複合体 / MHC class II … More Except Principal Investigator 認知機能障害 / 全身性エリテマトーデス / 抗リン脂質抗体（aPL） / 精神神経SLE / サイトカイン / 亜型解析 / 遺伝学的解析 / 疾患レジストリ / 難病プラットフォーム / 疾患活動性指標 / レジストリ研究 / GWAS / クラスター解析 / ゲノム解析 / レジストリ / ベーチェット病 Less

Interaction between chronic inflammation, pain, and brain function in systemic lupus erythematosusPrincipal Investigator
- Principal Investigator
  
  藤枝雄一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Hokkaido University
Analysis of mechanism of antiphospholipid antibody-induced central nervous system impairment
- Principal Investigator
  
  Atsumi Tatsuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Hokkaido University
The prothrombin/MHC II complexes on cell-surface of monocytes is the antigenic targets in antiphospoholipid syndromePrincipal Investigator
- Principal Investigator
  
  Fujieda Yuichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Hokkaido University
Generation of evidence through registry construction by genome-wide subtype analysis of Behcet's disease
- Principal Investigator
  
  桐野洋平
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Yokohama City University
Pathogenesis of autoantibody production in antiphospholipid syndromePrincipal Investigator
- Principal Investigator
  
  Fujieda Yuichiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Hokkaido University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] リウマチ病学テキスト(改訂第3版)2022
- Author(s)
  藤枝雄一郎
- Total Pages
  6
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-19K08876
[Book] EBM血液疾患の治療2021－20222021
- Author(s)
  藤枝雄一郎、渥美達也
- Total Pages
  8
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19K08876
[Journal Article] IKBKE contributes to neuropsychiatric manifestations in lupus-prone mice through microglial activation.2023
- Author(s)
  Karino K, Kono M, Takeyama S, Kudo Y, Kanda M, Abe N, Aso K, Fujieda Y, Kato M, Oku K, Amengual O, Atsumi T
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 75(3) Issue: 3 Pages: 411-423
- DOI
  10.1002/art.42352
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03718, KAKENHI-PROJECT-20K08792, KAKENHI-PROJECT-21K16280
[Journal Article] 全身性エリテマトーデスにおけるストレス誘発性にミクログリアが産生するインターロイキン12/23の神経精神学的影響2022
- Author(s)
  阿部靖矢、垂水政人、藤枝雄一郎
- Journal Title
  
  リウマチ科
  
  Volume: 69（4） Pages: 454-465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03718
[Journal Article] Pathogenic neuropsychiatric effect of stress-induced microglial interleukin 12/23 axis in systemic lupus erythematosus2022
- Author(s)
  Abe Nobuya、Tarumi Masato、Fujieda Yuichiro、Takahashi Nobuhiko、Karino Kohei、Uchida Mona、Kono Michihito、Tanaka Yuki、Hasebe Rie、Kato Masaru、Amengual Olga、Arinuma Yoshiyuki、Oku Kenji、Sato Wakiro、Tha Khin Khin、Yamasaki Miwako、Watanabe Masahiko、Atsumi Tatsuya、Murakami Masaaki
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 81 Issue: 11 Pages: 1564-1575
- DOI
  10.1136/ard-2022-222566
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07062, KAKENHI-PROJECT-20H00502, KAKENHI-PROJECT-20H03718, KAKENHI-PROJECT-20K08792, KAKENHI-PROJECT-21K19364, KAKENHI-PROJECT-19K16903
[Journal Article] ストレスで誘導されるミクログリア由来のインターロイキン-12/23軸による精神神経ループスへの影響2022
- Author(s)
  阿部靖矢、垂水政人、藤枝雄一郎、渥美達也、村上正晃
- Journal Title
  
  北海道医学雑誌 2022年度 Best Articles of the Year
  
  Volume: 97 (2) Pages: 74-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03718
[Journal Article] Morbidity and mortality in antiphospholipid syndrome based on cluster analysis: a 10-year longitudinal cohort study2021
- Author(s)
  Ogata Y, Fujieda Y, Sugawara M, Sato T, Ohnishi N, Kono M, Kato M, Oku K, Amengual O, Atsumi T.
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: - Issue: 3 Pages: 1331-1337
- DOI
  10.1093/rheumatology/keaa542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08876, KAKENHI-PROJECT-20K08792
[Journal Article] New insights into the pathogenic mechanisms and treatment of arterial thrombosis in antiphospholipid syndrome2020
- Author(s)
  Fujieda Y, Amengual O
- Journal Title
  
  European Journal of Rheumatology
  
  Volume: - Issue: 2 Pages: 93-99
- DOI
  10.5152/eurjrheum.2020.20058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08876
[Journal Article] Has lupus anticoagulant testing had its day?2019
- Author(s)
  Fujieda Yuichiro、Atsumi Tatsuya
- Journal Title
  
  Nature Reviews Rheumatology
  
  Volume: 15 Issue: 6 Pages: 324-325
- DOI
  10.1038/s41584-019-0218-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08876
[Journal Article] Factor Xa inhibitors for preventing recurrent thrombosis in patients with antiphospholipid syndrome: a longitudinal cohort study2019
- Author(s)
  Sato T、Nakamura H、Fujieda Y、Ohnishi N、Abe N、Kono M、Kato M、Oku K、Bohgaki T、Amengual O、Yasuda S、Atsumi T
- Journal Title
  
  Lupus
  
  Volume: 28 Issue: 13 Pages: 1577-1582
- DOI
  10.1177/0961203319881200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08876
[Journal Article] Circulating plasmablasts contribute to antiphospholipid antibody production, associated with type I interferon upregulation2019
- Author(s)
  Hisada RYO、Kato Masaru、Sugawara ERI、Kanda Masatoshi、Fujieda Yuichiro、Oku Kenji、Bohgaki Toshiyuki、Amengual Olga、Horita Tetsuya、Yasuda Shinsuke、Atsumi Tatsuya
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: 17 Issue: 7 Pages: 1134-1143
- DOI
  10.1111/jth.14427
- NAID
  120006875078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] Microglial activation mediated by anti-b2GPI antibody leads to cognitive impairment and anxiety-like behavior in mice model.2022
- Author(s)
  Fujieda Y, Abe N, Kono M, Kato M, Amengual O, Atsumi T.
- Organizer
  17th International Congress on Antiphospholipid Antibodies,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03718
[Presentation] Improvement of long COVID-associated brain fog after COVID-19 vaccination in a patient with antiphospholipid antibodies.2022
- Author(s)
  Sakiyama K, Fujieda Y, Tada M, Tsuchida N, Nishino K, Moriya H, Yasuda M, Kono M, Kato M, Amengual O, Atsumi T.
- Organizer
  ICAPA2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03718
[Presentation] 抗リン脂質抗体症候群患者における新型コロナウイルスワクチン投与後の抗リン脂質抗体プロファイルの変化2022
- Author(s)
  藤枝雄一郎
- Organizer
  第16回日本血栓止血学会標準化委員会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] ループスモデルマウスにおける慢性ストレス誘導性IL-12/23p40による精神神経病態への影響2021
- Author(s)
  阿部靖矢、藤枝雄一郎、奥健志、河野通仁、田中勇希、加藤将、有沼良幸、佐藤和貴郎、村上正晃、渥美達也
- Organizer
  第49回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03718
[Presentation] Chronic stress-induced microglial interleukin-12/23 axis and medial prefrontal cortex impairment in neuropsychiatric lupus.2021
- Author(s)
  Abe N, Fujieda Y, Oku K, Takahashi N, Karino K, Uchida M, Kono M, Tanaka Y, Hasebe R, Kato M, Atsumi T, Murakami M.
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03718
[Presentation] APSレジストリの進捗2021
- Author(s)
  藤枝雄一郎
- Organizer
  第9回学術集会日本抗リン脂質抗体標準化ワークショップ
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] 全身性エリテマトーデスにおける慢性ストレス誘導性ミクログリア・IL-12/23軸賦活を介した精神神経学的影響2021
- Author(s)
  阿部靖矢、藤枝雄一郎、垂水政人、狩野皓平、河野通仁、田中勇希、加藤将、有沼良幸、奥健志、佐藤和貴郎、村上正晃、渥美達也
- Organizer
  第8回 JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-20H03718
[Presentation] 抗リン脂質抗体症候群におけるトランスレーショナルリサーチ2021
- Author(s)
  藤枝雄一郎
- Organizer
  第49回日本臨床免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] ループスモデルマウスにおける慢性ストレス誘導性IL-12p40による精神神経病態への影響2021
- Author(s)
  阿部靖矢、奥健志、藤枝雄一郎、狩野皓平、河野通仁、加藤将、田中勇希、村上正晃、渥美達也
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20H03718
[Presentation] 抗リン脂質抗体症候群患者における新型コロナウイルスワクチン投与後の抗リン脂質抗体プロファイルの変化2021
- Author(s)
  藤枝雄一郎
- Organizer
  第9回学術集会日本抗リン脂質抗体標準化ワークショップ
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] The effect of antiphospholipid antibody on cognitive function and microglial activation in mice.2020
- Author(s)
  Abe N, Oku K, Kudo Y, Karino K, Kono M, Fujieda Y, Amengual O, Kato M, Kamimura D, Yasuda S, Murakami M, Atsumi T.
- Organizer
  第64回日本リウマチ学会総会・学術集会（WEB)
- Data Source
  KAKENHI-PROJECT-20H03718
[Presentation] Pathogenic Effect of Chronic Stress-induced interleukin-12/23p40 on Neuropsychiatric System in Lupus-prone Mouse.2020
- Author(s)
  Abe N, Oku K, Fujieda Y, Takahashi N, Karino K, Kono M, Kato M, Tanaka Y, Hasebe R, Amengual O, Yamasaki M, Watanabe M, Murakami M, Atsumi T.
- Organizer
  The American College of Rheumatology Convergence 2020 Annual Meeting, virtual congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03718
[Presentation] ループスモデルマウスにおける慢性ストレス誘導性IL-12/23p40による精神神経病態への影響2020
- Author(s)
  阿部靖矢、奥健志、藤枝雄一郎、渥美達也、村上正晃．
- Organizer
  第6回北海道大学部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-20H03718
[Presentation] The prothrombin/MHC class II complexes on procoagulant cells as the novel immune target for pathogenic antiphospholipid antibodies.2020
- Author(s)
  Fujieda Y, Ohnishi N, Kono M, Kato M, Oku K, Amengual O, Arase H, Atsumi T.
- Organizer
  The International Society on Thrombosis and Haemostasis 2020 Virtual Congress 2020 virtual congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] 単球細胞表面上のプロトロンビン/MHC class II複合体は抗リン脂質抗体の新規対応抗原である2020
- Author(s)
  藤枝雄一郎、大西直樹、河野通仁、加藤将、奥健志、Olga Amengual、荒瀬尚、渥美達也
- Organizer
  第42回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] The prothrombin/MHC class II complexes on procoagulant cells as the novel immune target for pathogenic antiphospholipid antibodies2019
- Author(s)
  Ohnishi N, Fujieda Y, Kono M, Kato M, Oku K, Bohgaki T, Amengual O, Yasuda S, Hisashi Arase, Atsumi T
- Organizer
  The International Society on Thrombosis and Hemostasis (ISTH)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] Longitudinal efficacy and safety of direct factor Xa inhibitors. in patients with antiphospholipid syndrome.2019
- Author(s)
  Sato T, Amengual O, Fujieda Y, Nakamura H, Ohnishi N, Abe N, Kono Michihito, Kato M, Oku K, Bohgaki T, Yasuda S, Atsumi T.
- Organizer
  The 16th International Congress on Antiphospholipid Antibodies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] Discrimination of intracranial vasculitis from thrombotic antiphospholipid syndrome in lupus patients with antiphospholipid antibodies.2019
- Author(s)
  Aso K, Fujieda Y, Sato T, Ohnishi N, Kono M, Kato M, Oku K, Amengual O, Yasuda S, Atsumi T
- Organizer
  16th International Congress on Antiphospholipid Antibodies (ICAPA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] Prothrombin/MHC class II complexes on procoagulant cells are novel immune target for pathogenic antiphospholipid antibodies2019
- Author(s)
  Ohnishi N, Fujieda Y, Kono M, Kato M, Oku K, Bohgaki T, Amengual O, Yasuda S, Hisashi Arase, Atsumi T.
- Organizer
  16th International Congress on Antiphospholipid Antibodies (ICAPA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] IgM antiphospholipid antibodies: long term follow-up and thrombotic risk.2019
- Author(s)
  Sato T, Amengual O, Fujieda Y, Nakamura H, Ohnishi N, Abe N, Kono Michihito, Kato M, Oku K, Bohgaki T, Yasuda S, Atsumi T
- Organizer
  The International Society on Thrombosis and Hemostasis (ISTH)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08876
[Presentation] A novel antigen presentation in antiphospholipid syndrome2018
- Author(s)
  Naoki Ohnishi, Yuichiro Fujieda
- Organizer
  2018 ACR/ARHP Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16202

1. Atsumi Tatsuya (20301905)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. 桐野洋平 (50468154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 小林大介 (00363507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 吉藤元 (20422975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 國崎玲子 (20457849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中島秀明 (30217723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 田中良哉 (30248562)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 岳野光洋 (50236494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 土橋浩章 (50380176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 目黒明 (60508802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 寺尾知可史 (60610459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 黒沢美智子 (70245702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 東野俊洋 (70458818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 吉見竜介 (70585265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 菊地弘敏 (80338681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 竹内正樹 (80794081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 廣畑俊成 (90189895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 川上純 (90325639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 水木信久 (90336579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 古賀智裕 (90537284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 宮川一平 (10525463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 大村浩一郎 (40432372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. Tha KhinKhin (20451445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 白川久志 (50402798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 奥健志 (70544295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
26. Ohnishi Naoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. HASEBE Rie

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujieda Yuichiro 藤枝 雄一郎

Research Projects

Research Products

Co-Researchers

Interaction between chronic inflammation, pain, and brain function in systemic lupus erythematosusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of mechanism of antiphospholipid antibody-induced central nervous system impairment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The prothrombin/MHC II complexes on cell-surface of monocytes is the antigenic targets in antiphospoholipid syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation of evidence through registry construction by genome-wide subtype analysis of Behcet's disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathogenesis of autoantibody production in antiphospholipid syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] リウマチ病学テキスト(改訂第3版)2022

Author(s)

Total Pages

Publisher

Data Source

[Book] EBM血液疾患の治療2021－20222021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] IKBKE contributes to neuropsychiatric manifestations in lupus-prone mice through microglial activation.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 全身性エリテマトーデスにおけるストレス誘発性にミクログリアが産生するインターロイキン12/23の神経精神学的影響2022

Author(s)

Journal Title

Data Source

[Journal Article] Pathogenic neuropsychiatric effect of stress-induced microglial interleukin 12/23 axis in systemic lupus erythematosus2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ストレスで誘導されるミクログリア由来のインターロイキン-12/23軸による精神神経ループスへの影響2022

Author(s)

Journal Title

Data Source

[Journal Article] Morbidity and mortality in antiphospholipid syndrome based on cluster analysis: a 10-year longitudinal cohort study2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] New insights into the pathogenic mechanisms and treatment of arterial thrombosis in antiphospholipid syndrome2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Has lupus anticoagulant testing had its day?2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Factor Xa inhibitors for preventing recurrent thrombosis in patients with antiphospholipid syndrome: a longitudinal cohort study2019

Author(s)

Journal Title

Fujieda Yuichiro 藤枝雄一郎