NAGAO MANABU 長尾学

… Alternative Names

Nagao Manabu 長尾学

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Researcher Number	70866029
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 特命准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 神戸大学, 医学研究科, 特命助教 2020 – 2021: 神戸大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 心不全 / 拡張機能障害型心不全 / トランスサイレチン蛋白 / 野生型トランスサイレチン型心アミロイドーシス / グルタミン / 2型糖尿病 / 心臓リモデリング / グルタミン代謝 / 心筋代謝リモデリング / 糖尿病性心筋症 / 心筋代謝 / グルタミノリシス … More Except Principal Investigator … More 心不全 / 心筋代謝リモデリング / 心臓線維化 / denovo脂肪酸合成 / 脂質代謝物 / 認知症 / フレイル / 脂質代謝 / 心筋インスリン抵抗性 / 2型糖尿病 / 分岐鎖アミノ酸 / 分岐鎖アミノ酸代謝 / 糖尿病性心筋症 / 心臓リモデリング / グルタミン代謝 / 心肥大 / グルタミン分解 / グルタミン / グルタミナーゼ1 / 心筋代謝 / グルタミノリシス Less

超高齢社会における健康寿命延伸に寄与する脂質代謝物の探索的研究
- Principal Investigator
  
  石田達郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
de novo 脂肪酸合成経路に着目した心臓線維化の分子機序解明と治療法の確立
- Principal Investigator
  
  小林成美
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
野生型トランスサイレチン型心アミロイドーシスの簡易診断法の確立Principal Investigator
- Principal Investigator
  
  長尾学
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
分岐鎖アミノ酸代謝に注目した糖尿病性心筋症の病態解明と治療応用
- Principal Investigator
  
  田中秀和
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
Elucidation of regulatory mechanisms of glutamine metabolism in heart failure and development of novel therapeutic strategies
- Principal Investigator
  
  Satomi-Kobayashi Seimi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
Establishment of a new biomarker and treatment for diabetic cardiomyopathyPrincipal Investigator
- Principal Investigator
  
  Nagao Manabu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Importance of B-Type Natriuretic Peptide in the Detection of Patients With Structural Heart Disease in a Primary Care Setting2024
- Author(s)
  Fujimoto Wataru、Odajima Susumu、Okamoto Hiroshi、Iwasaki Masamichi、Nagao Manabu、Konishi Akihide、Shinohara Masakazu、Toh Ryuji、Okuda Masanori、Hirata Ken-ichi、Tanaka Hidekazu
- Journal Title
  
  Circ J
  
  Volume: 88 Issue: 5 Pages: 732-739
- DOI
  10.1253/circj.CJ-23-0930
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2024-04-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08205
[Journal Article] Association Between Serum 3-Hydroxyisobutyric Acid and Prognosis in Patients With Chronic Heart Failure　― An Analysis of the KUNIUMI Registry Chronic Cohort ―2023
- Author(s)
  Fujimoto Wataru、Nagao Manabu、Nishimori Makoto、Shinohara Masakazu、Takemoto Makoto、Kuroda Koji、Yamashita Soichiro、Imanishi Junichi、Iwasaki Masamichi、Todoroki Takafumi、Okuda Masanori、Tanaka Hidekazu、Ishida Tatsuro、Toh Ryuji、Hirata Ken-ichi
- Journal Title
  
  Circ J
  
  Volume: 88 Issue: 1 Pages: 110-116
- DOI
  10.1253/circj.CJ-23-0577
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2023-12-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08205
[Journal Article] Plasma cystine/methionine ratio is associated with left ventricular diastolic function in patients with heart disease2023
- Author(s)
  Asakura Junko、Nagao Manabu、Shinohara Masakazu、Nishimori Makoto、Yoshikawa Sachiko、Iino Takuya、Seto Yutaro、Tanaka Hidekazu、Satomi-Kobayashi Seimi、Ishida Tatsuro、Hirata Ken-ichi、Toh Ryuji
- Journal Title
  
  Heart and Vessels
  
  Volume: 38 Issue: 12 Pages: 1422-1430
- DOI
  10.1007/s00380-023-02302-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08205, KAKENHI-PROJECT-21K08105
[Journal Article] Inhibition of glutaminase 1-mediated glutaminolysis improves pathological cardiac remodeling2022
- Author(s)
  Yoshikawa Sachiko、Nagao Manabu、Toh Ryuji、Shinohara Masakazu、Iino Takuya、Irino Yasuhiro、Nishimori Makoto、Tanaka Hidekazu、Satomi-Kobayashi Seimi、Ishida Tatsuro、Hirata Ken-Ichi
- Journal Title
  
  American Journal of Physiology-Heart and Circulatory Physiology
  
  Volume: 322 Issue: 5 Pages: H749-H761
- DOI
  10.1152/ajpheart.00692.2021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08491, KAKENHI-PROJECT-21K08105, KAKENHI-PROJECT-20K17081
[Journal Article] Critical role of glutamine metabolism in cardiomyocytes under oxidative stress2021
- Author(s)
  Watanabe Koichi、Nagao Manabu、Toh Ryuji、Irino Yasuhiro、Shinohara Masakazu、Iino Takuya、Yoshikawa Sachiko、Tanaka Hidekazu、Satomi-Kobayashi Seimi、Ishida Tatsuro、Hirata Ken-ichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 534 Pages: 687-693
- DOI
  10.1016/j.bbrc.2020.11.018
- NAID
  120006954850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17081
[Presentation] Implications of Altered Amino Acid Metabolism in the Failing Heart2024
- Author(s)
  長尾　学
- Organizer
  第８８回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08105
[Presentation] Implications of Altered Amino Acid Metabolism in the Failing Heart2024
- Author(s)
  長尾　学
- Organizer
  第８８回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08205
[Presentation] Inhibition of glutaminase1-dependent glutaminolysis improves pathological cardiac remodeling2022
- Author(s)
  Sachiko Yoshikawa, Manabu Nagao, Ryuji Toh, Masakazu Shinohara, Takuya Iino, Makoto Nishimori, Yasuhiro Irino, Hidekazu Tanaka, Seimi Satomi-Kobayashi, Tatsuro Ishida, Ken-ichi Hirata
- Organizer
  第86回日本循環器学会総会
- Data Source
  KAKENHI-PROJECT-20K17081
[Presentation] Inhibition of Glutaminase1-dependent Glutaminolysis Improves Pathological Cardiac Remodeling2021
- Author(s)
  吉川　祥子*、長尾　学、杜　隆嗣、篠原　正和、飯野　琢也、西森　誠、入野　康宏、田中　秀和、小林　成美、石田　達郎、平田　健一
- Organizer
  第86回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17081
[Presentation] Inhibition of glutaminase1-mediated glutaminolysis ameliorates angiotensin II-induced cardiac remodeling2021
- Author(s)
  Sachiko Yoshikawa, Manabu Nagao, Ryuji Toh, Masakazu Shinohara, Takuya Iino, Hidekazu Tanaka, Seimi Satomi-Kobayashi, Tatsuro Ishida, Ken-ichi Hirata
- Organizer
  第5回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-20K17081
[Presentation] Inhibition of Glutaminase1-dependent Glutaminolysis Improves Pathological Cardiac Remodeling2021
- Author(s)
  吉川　祥子*、長尾　学、杜　隆嗣、篠原　正和、飯野　琢也、西森　誠、入野　康宏、田中　秀和、小林　成美、石田　達郎、平田　健一
- Organizer
  第86回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08105
[Presentation] Inhibition of glutaminase1-mediated glutaminolysis ameliorates angiotensin II-induced cardiac remodeling2021
- Author(s)
  Sachiko Yoshikawa, Manabu Nagao, Ryuji Toh, Masakazu Shinohara, Takuya Iino, Hidekazu Tanaka, Seimi Satomi-Kobayashi, Tatsuro Ishida, Ken-ichi Hirata
- Organizer
  第5回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-21K08105
[Presentation] Critical roles of glutamine metabolism in failing heart2020
- Author(s)
  長尾　学
- Organizer
  Cardiovascular and metabolic week2020
- Data Source
  KAKENHI-PROJECT-20K17081
[Presentation] Crucial Role of Cardiac Glutamine Metabolism under Oxidative Stress2020
- Author(s)
  長尾　学
- Organizer
  Cardiovascular and metabolic week2020
- Data Source
  KAKENHI-PROJECT-20K17081
[Presentation] Critical Role of Cardiac Glutamine Metabolism under Oxidative Stress2020
- Author(s)
  長尾　学
- Organizer
  第85回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17081

1. Satomi-Kobayashi Seimi (20379415)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 杜隆嗣 (50379418)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 篠原正和 (80437483)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 田中秀和 (20590342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 石田達郎 (00379413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAGAO MANABU 長尾 学

Nagao Manabu 長尾 学

Research Projects

Research Products

Co-Researchers

超高齢社会における健康寿命延伸に寄与する脂質代謝物の探索的研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

de novo 脂肪酸合成経路に着目した心臓線維化の分子機序解明と治療法の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

野生型トランスサイレチン型心アミロイドーシスの簡易診断法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

分岐鎖アミノ酸代謝に注目した糖尿病性心筋症の病態解明と治療応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of regulatory mechanisms of glutamine metabolism in heart failure and development of novel therapeutic strategies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a new biomarker and treatment for diabetic cardiomyopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Importance of B-Type Natriuretic Peptide in the Detection of Patients With Structural Heart Disease in a Primary Care Setting2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Association Between Serum 3-Hydroxyisobutyric Acid and Prognosis in Patients With Chronic Heart Failure ― An Analysis of the KUNIUMI Registry Chronic Cohort ―2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Plasma cystine/methionine ratio is associated with left ventricular diastolic function in patients with heart disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of glutaminase 1-mediated glutaminolysis improves pathological cardiac remodeling2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Critical role of glutamine metabolism in cardiomyocytes under oxidative stress2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Implications of Altered Amino Acid Metabolism in the Failing Heart2024

Author(s)

Organizer

Data Source

[Presentation] Implications of Altered Amino Acid Metabolism in the Failing Heart2024

Author(s)

Organizer

NAGAO MANABU 長尾学

Nagao Manabu 長尾学

[Journal Article] Association Between Serum 3-Hydroxyisobutyric Acid and Prognosis in Patients With Chronic Heart Failure　― An Analysis of the KUNIUMI Registry Chronic Cohort ―2023