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OKAICHI Kumio  岡市 協生

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岡市 協生

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Researcher Number 80124874
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2013 – 2016: 長崎大学, 原爆後障害医療研究所, 准教授
2012: 長崎大学, 医歯(薬)学総合研究科, 准教授
2003 – 2005: 長崎大学, 大学院・医歯薬学総合研究科, 助教授
1995 – 2002: 長崎大学, 医学部, 助教授
1986: 奈良県立医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Biological Sciences / 環境影響評価(含放射線生物学)
Except Principal Investigator
Radiation science / 生物資源科学 / 放射線5生物学 / Radiation science / Risk sciences of radiation/Chemicals
Keywords
Principal Investigator
p53 / 放射線感受性 / アポトーシス / 放射線耐性 / 癌治療 / 遺伝子導入 / 変異部位 / 制癌剤 / スクリーニング / 放射線治療 … More / signal transduction / シグナル伝達 / Saos-2 / phosphorylation / radiation response / crosstalk / environmental stress / 環境ストレ / リン酸化 / 放射線応答 / クロストーク / 環境ストレス / transduction / apoptosis / radio-sensitivity / mutation / SaOS-2 / G1停止 / Saos2 / シグナルトランスダクション / 突然変異 … More
Except Principal Investigator
RBE / scid cells / DNA-PK activity / DNA double strand breaks / radiosensitivity / heavy ion particles / DNA-PK活性 / DNA二重鎖切断 / 重粒子線 / 放射線感受性 / scid細胞 / DNA二重鎖 / endocrine desruptors / inhibition of cell motility / mannuronate / active oxygens / red tide phytoplankton / inhibition of tumor cell growth / inhibition of melanogenesis / marine microorganism library / アルギン酸 / グルロン酸 / 微生物ライブラリー / ゲノムDNAライブラリー / 細胞増殖阻害 / 内分泌撹乱物質 / 細胞遊走抑制 / マンヌロン酸 / 活性酸素 / 赤潮プランクトン / 癌細胞増殖阻害 / メラニン生成抑制 / 海洋微生物ライブラリー / DNAニ重鎖切断 / NIH3T3 Cells / Thermosensitivity / Oncogene / NIH3T3細胞 / 熱感受性 / 癌遺伝子 / ピリミジンダイマー / DNA修復酵素遺伝子 / DNA修復能 / 細胞性粘菌 / p53 / 腫瘍浸潤 / FDG PET / テーラーメイド医療 / 膵癌 / 核医学 / リスクコミュニケーション / 福島原発事故 / 分子イメージング / 放射性ヨウ素 / 内部被ばく Less
  • Research Projects

    (15 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (18 People)
  •  Development of patient specific medicine using FDG PET and gene expression

    • Principal Investigator
      KUDO Takashi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Nagasaki University
  •  Evaluation of health risk of internal exposure with radioactive iodine by molecular imaging

    • Principal Investigator
      MATSUDA Naoki
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Nagasaki University
  •  各種変異p53遺伝子導入細胞のマイクロプレートによる放射線・制癌剤感受性の測定Principal Investigator

    • Principal Investigator
      岡市 協生
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagasaki University
  •  Crosstalk of signal transduction of p53 by various stress from environmentsPrincipal Investigator

    • Principal Investigator
      OKAICHI Kumio
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Nagasaki University
  •  各種変異p53遺伝子導入細胞による放射線治療と制癌剤のスクリーニングシステムPrincipal Investigator

    • Principal Investigator
      岡市 協生
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagasaki University
  •  各種変異p53遺伝子導入細胞による放射線治療と制癌剤のスクリーニングシステムPrincipal Investigator

    • Principal Investigator
      岡市 協生
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagasaki University
  •  Radiosensitivity of Scid Cells Deficient in Repair of DNA Damages Induced by High LET Irradiation

    • Principal Investigator
      OKUMURA Yutaka
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Nagasaki University
  •  p53の変異部位に対応した放射線による癌治療法の開発Principal Investigator

    • Principal Investigator
      岡市 協生
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagasaki University
  •  The development of materials for foods and drugs by bio-power of marine microorganisms

    • Principal Investigator
      KODAMA Seiji
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for University and Society Collaboration
    • Research Field
      生物資源科学
    • Research Institution
      Nagasaki University
  •  p53の変異部位に対応した放射線による癌治療法の開発Principal Investigator

    • Principal Investigator
      岡市 協生
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagasaki University
  •  p53の変異部位に対応した放射線による癌治療法の開発Principal Investigator

    • Principal Investigator
      岡市 協生
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagasaki University
  •  Radiosensitivity of scid cells for heavy ion particles

    • Principal Investigator
      OKUMURA Yutaka
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      NAGASAKI UNIVERSITY
  •  The changes of radio-sensitivity and signal transduction by mutation in p53Principal Investigator

    • Principal Investigator
      OKAICHI Kumio
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Nagasaki University
  •  Analysis of Thermotolerance of Cancer by Introduction of Oncogeges

    • Principal Investigator
      OKUMURA Yutaka
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Nagasaki University
  •  細胞性粘菌のDNA修復酵素遺伝子radCのクローニング

    • Principal Investigator
      大西 武雄
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      放射線5生物学
    • Research Institution
      Nara Medical University

All 2015 2006 2005 2004 2003 2002

All Journal Article Presentation Book

  • [Book] Low dose of wortmannin reduces radiosensitivity of cells. in "Radiation and Humankind."2002

    • Author(s)
      Okaichi, K
    • Total Pages
      556
    • Publisher
      Elsevier Science
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Book] Radiation sensitivity and mutation position of p53. in "Radiation and Homeostasis."2002

    • Author(s)
      Okaichi, K
    • Total Pages
      308
    • Publisher
      Elsevier Science
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Sucralfate Protects Intestinal Epithelial Cells From Radiation-Induced Apoptosis in Rats.2006

    • Author(s)
      Matsuu-Matsuyama, M., Shichijo, K., Okaichi, K, Ishii, K., Wen, CY, Fukuda, E., Nakayama, T., Nakashima, M., Okumura, Y., Sekine, I.
    • Journal Title

      J.Radiat.Res. 47

      Pages: 1-8

    • NAID

      110004701145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] 癌細胞で見つかる各種変異p53シグナルの放射線感受性への関与2006

    • Author(s)
      岡市協生, 井手美和, 奥村 寛
    • Journal Title

      広島医学 印刷中

    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] 癌細胞で見つかる各種変異p53シグナルの放射線感受性への関与2006

    • Author(s)
      岡市協生
    • Journal Title

      広島医学 (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Sympathetic hyperfunction causes high autonomic nervous system sensitivity to whole-body X-ray irradiation.2005

    • Author(s)
      Matsuu, M., Shichijo, K, Ikeda, Y., Ito, M., Naito, S., Okaichi, K., Nakashima, M., Nakayama, T., Sekine, I.
    • Journal Title

      Radiat.Res. 163

      Pages: 137-143

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Hypergravity induces phosphorylation of p53 at serine 15 but not expression of p53-downstream genes.2004

    • Author(s)
      Okaichi, K, Ide, M., Usui, A., Okumura, Y.
    • Journal Title

      J.Radiat.Res. 45

      Pages: 399-403

    • NAID

      110004041041

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] 放射線応答におけるp53リン酸化の役割2004

    • Author(s)
      岡市協生, その他
    • Journal Title

      長崎医学会雑誌 79

      Pages: 93-96

    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Hypergravity induces pholosphorylation of p53 at serine 15 but not expression of p53-downstream genes.2004

    • Author(s)
      Okaichi, K., et al.
    • Journal Title

      J.Radiat.Res. 45

      Pages: 399-403

    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Hypergravity induces phosphorylation of p53 at serine 15 but not expression of p53-downstream genes.2004

    • Author(s)
      Okaichi, K
    • Journal Title

      J. Radiat. Res. 45

      Pages: 399-403

    • NAID

      110004041041

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] 放射線応答におけるp53リン酸化の役割2004

    • Author(s)
      岡市協生
    • Journal Title

      長崎医学会雑誌 79

      Pages: 93-96

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Radiation sensitivity and mutation position of p53.2003

    • Author(s)
      Okaichi, K., Ide, M., Okumura, Y.
    • Journal Title

      Radiation and Humankind, Elsevier Science,(Shibata, Y., Yamashita, S., Watanabe, M., Tominaga, M.(eds))

      Pages: 239-243

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] The protective effect of fermented milk Kefir on radiation-induced apoptosis in colonic crypt cells of rats.2003

    • Author(s)
      Matsuu, M., Shichijo, K., Okaichi, K, Wen, Y.C., Fukuda, E., Nakashima, M., Nakayama, T., Shirahata, S., Tokumaru, S., Sekine, I.
    • Journal Title

      J.Radiat.Res. 44

      Pages: 111-115

    • NAID

      110002328873

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Low dose of wortmannin reduces radiosensitivity of cells.2002

    • Author(s)
      Okaichi, K., Suzuki, K., Morita, N., Ikeda, M., Matsuda, N., Takahashi, H., Watanabe M., Okumura, Y.
    • Journal Title

      Radiation and Homeostasis, Elsevier Science (Sugahara, T., Nikaido, O., Niwa, O.(eds))

      Pages: 359-362

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] p53はどこから来たか2002

    • Author(s)
      岡市協生
    • Journal Title

      放射線生物研究 37

      Pages: 43-52

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] 癌細胞で見つかる各種変異p53遺伝子の作成2002

    • Author(s)
      岡市協生
    • Journal Title

      長崎医学会雑誌 77

      Pages: 329-331

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Hypergravity modified the signal transduction of ionizing radiation through p53.2002

    • Author(s)
      Okaichi, K., Usui, A., Ohnishi, T., Okumura, Y.
    • Journal Title

      J.Radiat.Res. 43

    • NAID

      110002328993

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] 低線量放射線によるp53シグナルの環境ストレスによる修飾2002

    • Author(s)
      岡市協生
    • Journal Title

      広島医学 55

      Pages: 278-279

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Low dose of wortmannin reduces radiosensitivity of human glioblastoma cells through the p53 pathway.2002

    • Author(s)
      Okaichi, K
    • Journal Title

      Oncol. Rep. 9

      Pages: 859-862

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Hypergravity modified the signal transduction of ionizing radiation through p53.2002

    • Author(s)
      Okaichi, K
    • Journal Title

      J. Radiat. Res 43

      Pages: 261-264

    • NAID

      110002328993

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Journal Article] Low dose of wortmannin reduces radiosensitivity of human glioblastoma cells through the p53 pathway.2002

    • Author(s)
      Okaichi, K., Suzuki, K., Morita, N., Ikeda, M., Takahashi, H., Matsuda, N., Watanabe M., Okumura, Y.
    • Journal Title

      Oncol.Rep. 9

      Pages: 859-862

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380255
  • [Presentation] Low Dose Ionizing Radiation Induces Various MicroRNAs with the Assistance of p532015

    • Author(s)
      Kumio Okaichi
    • Organizer
      15th International Congress of Radiation Research
    • Place of Presentation
      京都国際会議場(京都府・京都市)
    • Year and Date
      2015-05-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461857
  • 1.  OKUMURA Yutaka (00073130)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 7 results
  • 2.  IHARA Makoto (60175213)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  KUDO Takashi (20330300)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  MATSUDA Naoki (00304973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  NAKAYAMA Morio (60164373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SIMASAKI Tatsuya (60264248)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KODAMA Seiji (00195744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  UEDA Hiroshi (00145674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KOBAYASHI Nobuyuki (30150329)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  WATANABE Masami (20111768)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  ODA Tatsuya (60145307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TAKESHITA Satoshi (20295083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  吉田 正博 (50264247)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  福岡 順也 (00324575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  上谷 雅孝 (40176582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  七島 篤志 (60380838)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  大西 武雄 (60094554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  野津 敬一 (60028090)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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