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IZUMI KENZI  泉 健次

… Alternative Names

IZUMI Kenji  泉 健次

泉 健次  イズミ ケンジ

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Researcher Number 80242436
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6302-6828
Affiliation (Current) 2025: 新潟大学, 医歯学系, 教授
Affiliation (based on the past Project Information) *help 2012 – 2024: 新潟大学, 医歯学系, 教授
2009 – 2012: 新潟大学, 医歯学系, 准教授
2001: 新潟大学, 大学院・医歯学総合研究科, 助手
2000: 新潟大学, 歯学部, 助手
1993 – 1996: 新潟大学, 歯学部, 助手
Review Section/Research Field
Principal Investigator
Dental engineering/Regenerative dentistry / Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related / Basic Section 90130:Medical systems-related / Basic Section 90140:Medical technology assessment-related / Basic Section 57040:Regenerative dentistry and dental engineering-related / Pathobiological dentistry/Dental radiology / Surgical dentistry
Except Principal Investigator
Dental engineering/Regenerative dentistry / Basic Section 57050:Prosthodontics-related / Basic Section 90140:Medical technology assessment-related … More / Prosthodontics/ Dental materials science and / Surgical dentistry / Morphological basic dentistry / Basic Section 57020:Oral pathobiological science-related / Basic Section 57040:Regenerative dentistry and dental engineering-related / Surgical dentistry / Basic Section 57080:Social dentistry-related / Basic Section 44020:Developmental biology-related / Basic Section 57060:Surgical dentistry-related / Social dentistry / Oral Science and related fields / 病態科学系歯学(含放射線系歯学) Less
Keywords
Principal Investigator
口腔粘膜上皮細胞 / 再生医療 / 口腔粘膜角化細胞 / 口腔粘膜 / 口腔粘膜上皮 / 低酸素 / 上皮細胞 / 角化細胞 / 分化能 / 動画解析 … More / 非侵襲的細胞品質評価 / ヒト間葉系幹細胞 / 足場材硬さ / 角化 / 運動能 / 遺伝子発現 / 口腔ケラチノサイト / 硬さ / 上皮角化 / ヤング率 / 足場材 / Nカドヘリン / メカノトランスダクション / 培養口腔粘膜 / 非角化 / 正角化 / メカノバイオロジー / 培養口腔粘膜上皮細胞 / 品質管理 / 細胞品質管理 / 非侵襲的評価 / 再生歯学 / 画像解析 / 画像処理 / 非侵襲的細胞評価 / 細胞増殖能 / 細胞運動能 / CD8陽性T細胞 / 免疫特権 / 共培養 / インビトロモデル / CD8陽性T細胞 / 口腔扁平苔癬 / プローブ / 発光プローブ / 幹細胞ニッチ / PI3K/Aktシグナリング / アンチエイジング / PPARγ / PTEN / アゴニスト / PPARgamma / エイジング / Akt/mTOR / 老化 / 分泌タンパク / 分化 / 細胞老化 / TASCC / ウェスタンブロッティング / 前駆/幹細胞 / ラパマイシン / mTOR / オートファジー / 成長因子 / 血管新生 / 創傷治癒 / 真皮 / 細胞培養 / ティッシュエンジニアリング … More
Except Principal Investigator
口腔粘膜 / 歯根膜 / 三次元培養 / 口腔がん / インプラント / 口腔粘膜上皮細胞 / 口腔顎顔面再建外科学 / 再生 / 幹細胞 / がん治療 / 口腔癌 / 骨形成 / オッセオインテグレーション / チタン / 細胞制御 / ナノ構造 / 歯 / 骨再生 / 骨増生 / 細胞移植 / 移植・再生医療 / PI3K/Aktシグナリング / 細胞運動能 / 創傷治癒モデル / 皮膚 / 再生医療 / 機械受容器 / ルフィニ神経終末 / トランスレーショナルリサーチ / 3D モデル / オルガノイド / がん細胞の微小環境ネットワーク / 口腔癌3次元浸潤モデル / メタボロミクス解析 / scRNA-Seq解析 / シングルセルRNA-seq解析 / 液状検体化細胞診法 / Carcinoma Sequence / 非破壊的 / 品質評価法 / 画像イメージング / 角膜 / 培養口腔粘膜上皮シート / 口腔乾燥 / 唾液 / 女性ホルモン / 線維芽細胞 / フラクタル構造 / コラーゲン製足場材 / 口腔粘膜線維芽細胞 / 自家培養口腔粘膜 / タンパク質制御 / 体内埋め込み型生体材料 / 規格化ナノ構造チタン / 無構造超平滑チタン表面 / チタン接着タンパク質 / 超平滑チタン表面 / 貪食 / 細胞死 / コレステロール / 脂質クオリティ / 死細胞貪食 / 死細胞 / 脂質 / 生体イメージング / 遺伝子改変マウス / 皮膚再生 / ニッチ / 力学的環境 / 領域化 / 細胞外マトリクス / 皮膚老化 / 細胞外環境 / 幹細胞不均一性 / 表皮幹細胞 / 中性子線量 / 中性子捕捉反応 / 三次元培養モデル / ホウ素 / 三次元口腔がんモデル / 放射線飛跡検出器 / 線量評価 / 固体飛跡検出器 / ホウ素分布 / BNCT / 長期骨量維持 / 生理機能亢進細胞混合移植 / 抗酸化処理 / 機能亢進 / 酸化還元 / 酸化ストレス制御 / 活性酸素種 / レドックス制御 / 細胞系譜解析 / 培養上清 / 細胞増殖活性 / 系譜解析 / 細胞クラスター / 細胞追跡 / 細胞増殖 / 細胞追跡法 / 組織幹細胞 / 浸潤能 / SOX9 / TGF-β / 癌微小環境 / 癌関連線維芽細胞 / 蛋白質探索 / ナノチタン構造 / タンパク質 / 規格化ナノ構造 / 生体材料 / デンタルインプラント / 組織制御 / 唾液腺 / 創薬応用 / in vitro モデル / in vitroモデル / 口腔乾燥症 / 小唾液腺 / 非神経性コリン作動系 / アセチルコリン / 口腔粘膜上皮 / 骨 / 歯周組織 / 骨移植 / 骨造成 / 細胞カクテル / プライミング細胞 / 細胞誘導 / 血管新生 / 骨代謝制御 / プライミング細胞カクテル / 分化誘導 / ティッシュエンジニアリング / 骨増生法 / 微量金属分析 / 微量元素 / 元素分析 / 量子ビーム / 化学状態 / 構造解析 / 元素分布 / 微量金属元素 / 経鼻式持続陽圧装置 / 下顎前方移動装置 / 側方セファログラム分析 / 鼻CPAP治療 / マウスピース治療 / 併用理論 / nasal CRAP / 口腔装置 / 外科治療 / 併用治療 / LAUP / UPPP / 口腔装具 / nasal CPAP / 睡眠時無呼吸症候群 / epithelial rests of Malassez / Hertwig's root sheath / amelogenin / MNU, / odontogenic epithelium / マラッセの上皮遺残 / ヘルトビッヒの上皮鞘 / アメロジェニン / MNU / 歯原性腫瘍 / 歯原性上皮細胞 / 上皮幹細胞 / カルシウム濃度 / キャップ依存性mRNA翻訳 / mTORシグナル / 14-3-3σ / 細胞分化 / 蛍光イメージング / 骨髄由来幹細胞 / SDF-1 / 骨髄幹細胞 / 間葉系幹細胞 / 神経堤 / 血行性幹細胞 / PTEN / ケラチノサイト / 培養口腔粘膜上皮細胞 / 創傷治療 / ハイドロミックスゲル / 口腔培養粘膜 / 定量解析 / 三叉神経節 / 免疫細胞化学 / ASIC / イオンチャネル / ASIC3 / 品質管理 / リアルタイム検査 / 非侵襲検査 / セルソーティング / 前駆 / 発芽細胞 / 細胞培養 / セルソーター(FACS) / ALDH / Sphere / 前駆/幹細胞 / GDNF / 終末シュワン細胞 / 軸索-シュワン細胞相互作用 / 末梢神経再生 / カルシウムイオン / 歯根膜ルフィニ神経終末 / 機械受容 / カベオリン / カベオラ / 口腔粘膜疾患 / LFA-1 / CD45RO / CD45RA / CD8 / CD4 / Lichen Planus / Lichenoid Tissue Reaction Less
  • Research Projects

    (41 results)
  • Research Products

    (45 results)
  • Co-Researchers

    (77 People)
  •  Standardization of noninvasive methods to evaluate quality of MSCs by measuring cell motilityPrincipal Investigator

    • Principal Investigator
      泉 健次
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90140:Medical technology assessment-related
      Basic Section 90130:Medical systems-related
      Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related
    • Research Institution
      Niigata University
  •  Development of a tool to evaluate quality of cultured oral mucosal epithelial cell sheets for corneal transplantation using image analyses

    • Principal Investigator
      小林 亮太
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90140:Medical technology assessment-related
    • Research Institution
      Niigata University
  •  Elucidation of the molecular mechanisms in the microenvironment of oral cancer using single-cell RNA sequence analysis

    • Principal Investigator
      田沼 順一
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Niigata University
  •  血管網を有する口腔がん三次元培養モデルを用いた治療効果評価法の検証

    • Principal Investigator
      井川 和代
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90140:Medical technology assessment-related
    • Research Institution
      Okayama University
  •  口腔粘膜上皮細胞と線維芽細胞から成る2層性自家培養口腔粘膜の開発

    • Principal Investigator
      齋藤 夕子 (原夕子)
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      Niigata University
  •  エクオールは口腔乾燥症,味覚障害,舌痛症の新たな治療法となりうるか?

    • Principal Investigator
      伊藤 加代子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Niigata University
  •  Dead cell-mediated activation mechanisms in oral cancer: Exploring the changes in lipid quality by dead cell phagocytosis

    • Principal Investigator
      Yamazaki Manabu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Niigata University
  •  Development of biomaterials with controlled tissue formation via adhesive proteins using standardized nanostructured titanium

    • Principal Investigator
      Akiba Yosuke
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57050:Prosthodontics-related
    • Research Institution
      Niigata University
  •  運動能指標による骨分化能を識別するヒト間葉系幹細胞の非破壊的品質評価管理法の開発

    • Principal Investigator
      塩見 晶
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      Niigata University
  •  Enhancing Bone Regeneration by Redox Control

    • Principal Investigator
      Akiba Nami
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57050:Prosthodontics-related
    • Research Institution
      Niigata University
  •  Evaluation system of Dose Distribution in Boron Neutron Capture Therapy

    • Principal Investigator
      Igawa Kazuyo
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90140:Medical technology assessment-related
    • Research Institution
      Okayama University
  •  Compartmentalization of epithelial stem cells in skin development and homeostasis

    • Principal Investigator
      Sada Aiko
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Kyushu University
      Kumamoto University
  •  Investigation of the mechanism of ortho- and non-keratinization pattern using different stiffness of scaffold and its application for fabrication of tissue-engineered oral mucosaPrincipal Investigator

    • Principal Investigator
      Izumi Kenji
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      Niigata University
  •  Analysis of the function of cancer-associated fibroblasts (CAFs) in the invasion of oral cancer.

    • Principal Investigator
      Funayama Akinori
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Niigata University
  •  Biological reaction control using topography regulation of nanostructured titanium

    • Principal Investigator
      AKIBA YOSUKE
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57050:Prosthodontics-related
    • Research Institution
      Niigata University
  •  Elucidation of fate path and regulatory factors of periodontal ligament tissue stem cells

    • Principal Investigator
      Masaru Kaku
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57050:Prosthodontics-related
    • Research Institution
      Niigata University
  •  Bone regeneration with priming cell cocktail transplantation

    • Principal Investigator
      Nami Akiba
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Prosthodontics/ Dental materials science and
    • Research Institution
      Niigata University
  •  Development of Simultaneous Regeneration Treatment for Tooth and Periodontal Tissue -Possibility of Tooth Germ Transplantation-

    • Principal Investigator
      Yoshizawa Michiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Matsumoto Dental University
  •  Study for elucidating indiction mechanism of stem cells by manipulation molecule

    • Principal Investigator
      Ohazama Atsushi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Niigata University
  •  Challenges to development of "bioregenerative therapy"

    • Principal Investigator
      Ohazama Atsushi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Research Field
      Oral Science and related fields
    • Research Institution
      Niigata University
  •  Drug discovery for xerostomia treatment targeting oral mucosal epithelium-minor salivary gland units

    • Principal Investigator
      Kato Hiroko
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Social dentistry
    • Research Institution
      Osaka University
      Institute of Physical and Chemical Research
      Niigata University
  •  Development of evaluation system using noninvasive measurement of cell/colony motion of oral keratinocytes for quality control in regenerative medicinePrincipal Investigator

    • Principal Investigator
      Izumi Kenji
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Niigata University
  •  Development and application of the trace elements and micro structure analyses of tissue specimens using the quantum beams

    • Principal Investigator
      UO Motohiro
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Prosthodontics/ Dental materials science and
    • Research Institution
      Tokyo Medical and Dental University
  •  Investigation of Bone Marrow-derived Stem Cells in Periodontal Ligament

    • Principal Investigator
      KAKU Masaru
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Prosthodontics/ Dental materials science and
    • Research Institution
      Niigata University
  •  Development of optical hypoxic environment for manufacturing a tissue-engineered oral mucosa by utilizing a hypoxia-sensing luminescent probePrincipal Investigator

    • Principal Investigator
      IZUMI KENJI
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Niigata University
  •  14-3-3σシグナルを介した薬理学的増殖スイッチ操作による高機能培養粘膜の開発

    • Principal Investigator
      安島 久雄
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Niigata University
  •  Investigation into the mechanism of oral mucosa regeneration by tissue engineered oral mucosa fabricated with oral mucosal progenitor/stem cells -importance of angiogenesis-

    • Principal Investigator
      Yoshizawa Michiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Matsumoto Dental University
      Niigata University
  •  Development of an in vitro model of oral lichen planus by utilizing a characteristic of immune-privilegePrincipal Investigator

    • Principal Investigator
      IZUMI KENJI
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Niigata University
  •  Roles of new ion channel involved in the regeneration/development of the periodontal Ruffini endings

    • Principal Investigator
      MAEDA Takeyasu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Niigata University
  •  The verification of the effects on the epidermal wound healing by the topical application of the mixture of cultured oral keratinocytes and hydrogel.

    • Principal Investigator
      AJIMA hisao
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Niigata University
  •  Development of tissue engineered oral mucosa maintaining higher regenerative potential -application of oral mucosa progenitor/stem cells-

    • Principal Investigator
      YOSHIZAWA Michiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Niigata University
  •  Examination of signaling pathway specific to oral mucosa wound healing.- Difference between oral mucosa and epidermis -

    • Principal Investigator
      MAEDA Takeyasu
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Niigata University
  •  Development of age-less tissue-engineered oral mucosa substitutePrincipal Investigator

    • Principal Investigator
      IZUMI Kenji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Niigata University
  •  Development of an anti-aging protocol and maintaining undifferentiated state of oral mucosa keratinocyte progenitor/stem cells by pharmacological manipulation of autophagyPrincipal Investigator

    • Principal Investigator
      IZUMI Kenji
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Niigata University
  •  再生組織/細胞製品出荷前の非侵襲・リアルタイム検査による品質管理システムの開発

    • Principal Investigator
      飯田 明彦
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Niigata University
  •  口腔粘膜上皮前駆/幹細胞の分離・同定

    • Principal Investigator
      前田 健康
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Niigata University
  •  Elucidation of functional significance of caveola in periodontal mechanoreceptor

    • Principal Investigator
      MAEDA Takeyasu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Niigata University
  •  無血清培地で作成したヒト培養複合口腔粘膜が移植後創傷治癒に及ぼす影響の研究Principal Investigator

    • Principal Investigator
      泉 健次
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Surgical dentistry
    • Research Institution
      Niigata University
  •  睡眠時無呼吸症候群の歯科における集学的治療法の確立

    • Principal Investigator
      河野 正己
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Niigata University
  •  口腔粘膜のLichenoid Tissue Reaction に関する組織学的研究

    • Principal Investigator
      SUZUKI Ichirou
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Niigata University
  •  Morpholohical study on the pathological changes of odontogenic epithelium

    • Principal Investigator
      HAMAMOTO Yoshioki
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Niigata University

All 2023 2022 2021 2020 2019 2018 2016 2015 2014 2013 2011 2010 Other

All Journal Article Presentation Patent

  • [Journal Article] Cholesterol Is a Regulator of CAV1 Localization and Cell Migration in Oral Squamous Cell Carcinoma2023

    • Author(s)
      Chan NN, Yamazaki M, Maruyama S, Abe T, Haga K, Kawaharada M, Izumi K, Kobayashi T, Tanuma JI.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 7 Pages: 6035-6035

    • DOI

      10.3390/ijms24076035

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09856, KAKENHI-PROJECT-23K09150
  • [Journal Article] Development of the Follow-Up Human 3D Oral Cancer Model in Cancer Treatment2023

    • Author(s)
      Kazuyo Igawa, Kenji Izumi, Yoshinori Sakurai
    • Journal Title

      BioTech

      Volume: 12 Issue: 2 Pages: 35-35

    • DOI

      10.3390/biotech12020035

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K11918
  • [Journal Article] Isolation and Culture of Primary Oral Keratinocytes from the Adult Mouse Palate2021

    • Author(s)
      Xuan Ngo Yen、Haga Kenta、Suzuki Ayako、Kato Hiroko、Yanagisawa Hiromi、Izumi Kenji、Sada Aiko
    • Journal Title

      Journal of Visualized Experiments

      Volume: 175 Issue: 175

    • DOI

      10.3791/62820

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03266, KAKENHI-PROJECT-20H03762
  • [Journal Article] Cells/colony motion of oral keratinocytes determined by non-invasive and quantitative measurement using optical flow predicts epithelial regenerative capacity2021

    • Author(s)
      Hoshikawa Emi、Sato Taisuke、Haga Kenta、Suzuki Ayako、Kobayashi Ryota、Tabeta Koichi、Izumi Kenji
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 10403-10403

    • DOI

      10.1038/s41598-021-89073-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19592, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-17H04398
  • [Journal Article] Crosstalk between oral squamous cell carcinoma cells and cancer-associated fibroblasts via the TGF-β/SOX9 axis in cancer progression2021

    • Author(s)
      Haga Kenta、Yamazaki Manabu、Maruyama Satoshi、Kawaharada Masami、Suzuki Ayako、Hoshikawa Emi、Chan Nyein Nyein、Funayama Akinori、Mikami Toshihiko、Kobayashi Tadaharu、Izumi Kenji、Tanuma Jun-ichi
    • Journal Title

      Translational Oncology

      Volume: 14 Issue: 12 Pages: 101236-101236

    • DOI

      10.1016/j.tranon.2021.101236

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10069, KAKENHI-PROJECT-19K10329, KAKENHI-PROJECT-21K09856, KAKENHI-PROJECT-21K10109
  • [Journal Article] Biological reaction control using topography regulation of nanostructured titanium2020

    • Author(s)
      Shiozawa Mayuko、Takeuchi Haruka、Akiba Yosuke、Eguchi Kaori、Akiba Nami、Aoyagi Yujin、Nagasawa Masako、Kuwae Hiroyuki、Izumi Kenji、Uoshima Katsumi、Mizuno Jun
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 2438-2445

    • DOI

      10.1038/s41598-020-59395-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11743, KAKENHI-PROJECT-18K09679
  • [Journal Article] Noninvasive Measurement of Cell/Colony Motion Using Image Analysis Methods to Evaluate the Proliferative Capacity of Oral Keratinocytes as a Tool for Quality Control in Regenerative Medicine2019

    • Author(s)
      Hoshikawa E, Sato T, Kimori Y, Suzuki A, Haga K, Kato H, Tabeta K,?Nanba D, Izumi K.
    • Journal Title

      J Tissue Eng

      Volume: 10 Pages: 204173141988152-204173141988152

    • DOI

      10.1177/2041731419881528

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04954, KAKENHI-PUBLICLY-19H05418, KAKENHI-PROJECT-17H04398, KAKENHI-PROJECT-17K10231, KAKENHI-PROJECT-16H06280
  • [Journal Article] Application of Hypoxic Exposure Combined with Osteogenic Induction for the Enhancement of Multiple Osteoinductive Capabilities in Rat Mesenchymal Cells.2018

    • Author(s)
      Saito N, Kato K, Akiba Y, Hara Y, Kojima T, Yoshizawa M, Ohazama A, Maeda T, Kobayashi T, Izumi K
    • Journal Title

      Open Journal of Stomatology

      Volume: 8 Pages: 53-69

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11923
  • [Journal Article] Hypoxia Induces an Undifferentiated Phenotype of Oral Keratinocytes in vitro2015

    • Author(s)
      Hiroko Kato, Kenji Izumi, Atsushi Uenoyama, et al.
    • Journal Title

      Cells Tissues Organs

      Volume: 199 Issue: 5-6 Pages: 393-404

    • DOI

      10.1159/000371342

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293420
  • [Journal Article] Enrichment of oral mucosa and skin keratinocyte progenitor/stem cells.2013

    • Author(s)
      (Izumi K), Marcelo CL, Feinberg SE.
    • Journal Title

      Methods Mol Biol

      Volume: 989 Pages: 293-303

    • DOI

      10.1007/978-1-62703-330-5_23

    • ISBN
      9781627033299, 9781627033305
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390371
  • [Journal Article] Enrichment of oral mucosa and skin keratinocyte progenitor/stem cells2013

    • Author(s)
      Izumi K, Marcelo CL, Feinberg SE
    • Journal Title

      Methods Mol Biol

      Volume: 989 Pages: 293-303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390371
  • [Journal Article] Detection of acid-sensing ionchannel 3(ASIC3) in periodontal Ruffini endings of mouse incisors2011

    • Author(s)
      Rahman F, Harada F, Saito I, Suzuki A, Kawano Y, Izumi K, Nozawa-Inoue K, Maeda T
    • Journal Title

      Neurosci Lett

      Volume: 488(2) Pages: 173-177

    • Data Source
      KAKENHI-PROJECT-20390464
  • [Journal Article] Intra-oral grafting of tissue-engineered human oral mucosa.2011

    • Author(s)
      Izumi K et al.
    • Journal Title

      Oral Craniofac. Tissue Eng.

      Volume: 1 Pages: 103-111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659857
  • [Journal Article] Raman spectroscopymonitoring of the cellular activities of atissue-engineeredex vivo produced oral mucosal equivalent2010

    • Author(s)
      Wen-Liang Lo, Kenji Izumi, et al
    • Journal Title

      J.Raman Spectrosc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592180
  • [Journal Article] 培養複合口腔粘膜移植を応用した口唇口蓋裂の2例2010

    • Author(s)
      飯田明彦, 芳澤享子, 泉健次, 他
    • Journal Title

      日本口蓋裂学会雑誌

      Volume: 35 Pages: 235-240

    • NAID

      10029089091

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592180
  • [Patent] がん治療法の有効性を評価するための方法、キット、構造物及び使用2022

    • Inventor(s)
      井川和代、泉健次、羽賀健太、内藤絵里子
    • Industrial Property Rights Holder
      井川和代、泉健次、羽賀健太、内藤絵里子
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-20K12714
  • [Patent] 細胞の品質評価方法,品質評価システム及び品質評価プログラム2018

    • Inventor(s)
      泉 健次,干川絵美,佐藤大祐,木森義隆
    • Industrial Property Rights Holder
      泉 健次,干川絵美,佐藤大祐,木森義隆
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-149488
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17H04398
  • [Presentation] 口腔癌および口腔粘膜3次元インビトロモデルに対する重粒子線照射の影響に関する研究2023

    • Author(s)
      泉 健次, 内藤絵里子, 井川和代, 羽賀健太, 小林亮太, 齋藤夕子, 山﨑 学, 田沼順一, 冨原 圭
    • Organizer
      第77回日本口腔科学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K09150
  • [Presentation] Cancer-associated fibroblasts promote the invasion of oral squamous cell carcinoma cells via the TGF-β/SOX9 axis2020

    • Author(s)
      Kenta Haga,Manabu Yamazaki, Satoshi Maruyama, Ayako Suzuki, Emi Hoshikawa, Akinori Funayama, Toshihiko Mikami, Tadaharu Kobayashi , Kenji Izumi, Jun-ichi Tanuma
    • Organizer
      The International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Data Source
      KAKENHI-PROJECT-19K10329
  • [Presentation] がん関連線維芽細胞は口腔扁平上皮癌においてSOX9発現を増強させ浸潤を促進する2019

    • Author(s)
      羽賀健太,山崎学,丸山智,鈴木絢子,干川絵美,船山昭典,三上俊彦,小林正治,泉健次,田沼順一
    • Organizer
      令和元年度新潟歯学会第2回例会
    • Data Source
      KAKENHI-PROJECT-19K10329
  • [Presentation] 細胞品質管理に向けた画像解析による口腔ケラチノサイトの非侵襲的,定量的運動能評価の試み2019

    • Author(s)
      干川絵美,木森義隆,佐藤大祐,加藤寛子,鈴木絢子,羽賀健太,難波大輔,多部田康一,泉 健次
    • Organizer
      第18回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-17H04398
  • [Presentation] Quantitative measurement of cell colony mobility using image analysis methods for quality control of oral keratinocytes2019

    • Author(s)
      Hoshikawa E, Kimori Y, Sato T, Kato H, Suzuki A, Haga K, Nanba D, Izumi K
    • Organizer
      The International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04398
  • [Presentation] 癌関連線維芽細胞は口腔扁平上皮癌細胞の遊走および浸潤を促進する-3次元培養モデルを用いた検討-2019

    • Author(s)
      羽賀健太,山崎学,丸山智,鈴木絢子,干川絵美,船山昭典,三上俊彦,田沼順一,小林正治,泉健次
    • Organizer
      第79回新潟癌治療研究会
    • Data Source
      KAKENHI-PROJECT-19K10329
  • [Presentation] Current and Future Research Topics on Tissue Engineering of Oral Mucosa2019

    • Author(s)
      Izumi K
    • Organizer
      The International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04398
  • [Presentation] Quantitative measurement of cell colony mobility using optical flow and normalized cross correlation as a non-invasive tool for quality control of oral keratinocytes2019

    • Author(s)
      Hoshikawa E,Kimori Y,Sato T,Kato H,Suzuki A,Haga K,Nanba D,Izumi K
    • Organizer
      Japan-Singapore International Skin Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04398
  • [Presentation] Noninvasive Cell Motion Monitoring Using Image Analysis Algorithms: A tool For Quality Control To Discriminate Epithelial Regenerative Capacity of Oral Keratinocytes2019

    • Author(s)
      Hoshikawa E, Sato T, Suzuki A, Haga K, Tabeta K, Nanba D, Izumi K
    • Organizer
      TERMIS-AM
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04398
  • [Presentation] Quantitative measurement of cell colony mobility using image analysis methods for quality control of oral keratinocytes: A preliminary study2018

    • Author(s)
      Hoshikawa E, Kimori Y, Sato T, Kato H, Suzuki A, Haga K, Nanba D, Izumi K
    • Organizer
      5th TERMIS World Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04398
  • [Presentation] 異なる培養環境において低酸素が口腔粘膜線維芽細胞の増殖活性に及ばす影響の検討2016

    • Author(s)
      原 夕子,加藤寛子,塩見 晶,高木律男,泉 健次
    • Organizer
      第4回低酸素研究会
    • Place of Presentation
      東京女子医科大学先端生命医科学研究所(東京都 新宿区)
    • Data Source
      KAKENHI-PROJECT-26293420
  • [Presentation] コラーゲンゲル内で3次元培養したヒト口腔粘膜線維芽細胞の低酸素応答2016

    • Author(s)
      原 夕子,加藤寛子,塩見 晶,高木律男,泉 健次
    • Organizer
      平成28年度新潟歯学会第2回例会
    • Place of Presentation
      新潟大学歯学部講堂(新潟県 新潟市)
    • Data Source
      KAKENHI-PROJECT-26293420
  • [Presentation] Metabolomic profile of human oral keratinocytes under hypoxic culture condition.2016

    • Author(s)
      Kato H, Sugimoto M, Hara Y, Saito N, Shiomi A, Izumi K
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2016-08-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293420
  • [Presentation] Hypoxic response of oral mucosa fibroblasts in a 3D collagen lattice2016

    • Author(s)
      Hara Y, Shiomi A, Kato H, Izumi K
    • Organizer
      TERMIS-AM
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2016-12-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293420
  • [Presentation] Metabolomic Profile of Human Oral Keratinocytes Under Hypoxic Culture Condition.2016

    • Author(s)
      Kato H, Sugimoto M, Hara Y, Saito N, Shiomi A, Izumi K:
    • Organizer
      International Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Place of Presentation
      Lombok, Indonesia
    • Year and Date
      2016-01-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293420
  • [Presentation] A novel approach to identify oral keratinocyte stem cells.2016

    • Author(s)
      Izumi K
    • Organizer
      The 39th annual scientific meeting of association for dental sciences of the republic of china
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2016-09-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293420
  • [Presentation] 口腔扁平苔癬インビトロモデル開発の試み2015

    • Author(s)
      泉 健次,加藤寛子,原 夕子,齋藤直朗,塩見 晶,金谷 貢,大川成剛
    • Organizer
      平成27年度日本歯科理工学会中部地方会夏季セミナー
    • Place of Presentation
      富士屋 (新潟県新潟市)
    • Year and Date
      2015-08-20
    • Data Source
      KAKENHI-PROJECT-26670817
  • [Presentation] Application of phosphorescent Ir(III) complex for monitoring oxygen levels in a tissue-engineered, ex vivo produced oral mucosa equivalent (EVPOME) - A preliminary study2015

    • Author(s)
      Izumi K, Yoshihara T, Kato H, Hara Y, Saito N, Maeda T, Tobita S
    • Organizer
      第3回低酸素研究会
    • Place of Presentation
      東京女子医科大学(東京都新宿区)
    • Year and Date
      2015-07-25
    • Data Source
      KAKENHI-PROJECT-26293420
  • [Presentation] Effects of Hypoxia on Human Oral Keratinocytes2014

    • Author(s)
      Hiroko Kato, Kenji Izumi, Stephen E. Feinberg
    • Organizer
      Research Day
    • Place of Presentation
      University of Michigan, Ann Arbor, MI, USA
    • Data Source
      KAKENHI-PROJECT-23659913
  • [Presentation] 低酸素環境が培養ヒト正常口腔粘膜上皮細胞に及ぼす影響2014

    • Author(s)
      泉健次、加藤寛子、塩見晶、上野山敦士、前田健康
    • Organizer
      第2回低酸素研究会
    • Place of Presentation
      東京都新宿区早稲田大学 先端生命医科学センター
    • Year and Date
      2014-07-26
    • Data Source
      KAKENHI-PROJECT-26293420
  • [Presentation] Effects of Hypoxia on Human Oral Keratinocytes2014

    • Author(s)
      Hiroko Kato, Kenji Izumi, Stephen E. Feinberg
    • Organizer
      Research Day @University of Michigan School of Dentistry
    • Place of Presentation
      Ann Arbor, MI, USA
    • Year and Date
      2014-02-19
    • Data Source
      KAKENHI-PROJECT-23659913
  • [Presentation] 培養口腔粘膜上皮細胞における細胞分化とTASCCに関する検討2013

    • Author(s)
      泉健次,加藤寛子,大貫尚志,齋藤太郎,塩見晶,上野山敦士,寺田典子,河野芳朗,野澤-井上佳世子,前田健康
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      高松
    • Data Source
      KAKENHI-PROJECT-22390371
  • [Presentation] 培養口腔粘膜上皮細胞における細胞分化とTASCCに関する検討2013

    • Author(s)
      (泉 健次)、加藤寛子、大貫尚志、齋藤太郎、塩見 晶、上野山敦士、寺田典子、河野芳朗、野澤-井上佳世子、前田健康
    • Organizer
      第118回日本解剖学会総会
    • Place of Presentation
      高松国際会議場(高松市)
    • Data Source
      KAKENHI-PROJECT-22390371
  • [Presentation] Clinical Trials in TE/RM : Oral Mucosa2011

    • Author(s)
      泉健次
    • Organizer
      4th International Conference on Biomedical Engineering
    • Place of Presentation
      Ho Chi Minh City(招待講演)
    • Year and Date
      2011-01-10
    • Data Source
      KAKENHI-PROJECT-22390371
  • [Presentation] Characterization of a unique subpopulation of oral mucosa keratinocytes produced from a monolayer culture : the omPUK cultured cell strain2010

    • Author(s)
      加藤寛子、泉健次、前田健康
    • Organizer
      International Joint Symposium on Oral Science
    • Place of Presentation
      Bali, Indonesia
    • Year and Date
      2010-12-17
    • Data Source
      KAKENHI-PROJECT-21659455
  • [Presentation] Characterization of a unique subpopulation of oral mucosa keratinocytes produced from a monolayer culture the omPUK cultured cell strain2010

    • Author(s)
      加藤寛子、泉健次、前田健康
    • Organizer
      35^<th> Japanese society for investigative dermatology
    • Place of Presentation
      和歌山市
    • Year and Date
      2010-12-04
    • Data Source
      KAKENHI-PROJECT-21659455
  • [Presentation] Hypoxia induces undifferentiated phenotype of oral keratinocytes in vitro

    • Author(s)
      Kato H, Izumi K, Shiomi A, Uenoyama A, Kuo S, Feinberg SE, Maeda T
    • Organizer
      TERMIS Americas 2014
    • Place of Presentation
      Renaissance Hotel, Washington, DC Downtown, Washington DC, USA
    • Year and Date
      2014-12-13 – 2014-12-16
    • Data Source
      KAKENHI-PROJECT-26293420
  • [Presentation] 低酸素環境が培養ヒト正常口腔粘膜上皮細胞に及ぼす影響

    • Author(s)
      泉健次、加藤寛子、塩見晶、上野山敦士、前田健康
    • Organizer
      第12回がんとハイポキシア研究会
    • Place of Presentation
      佐賀県佐賀市ホテルマリターレ創世佐賀
    • Year and Date
      2014-11-21 – 2014-11-22
    • Data Source
      KAKENHI-PROJECT-26293420
  • 1.  MAEDA Takeyasu (40183941)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 9 results
  • 2.  AKIBA YOSUKE (70547512)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 3.  YOSHIZAWA Michiko (60303137)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 4.  魚島 勝美 (50213400)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  OHZAMA Atsushi (40266169)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  KAKU Masaru (30547542)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  SUZUKI Akiko (70509538)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 8.  佐伯 万騎男 (30273692)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  照沼 美穂 (50615739)
    # of Collaborated Projects: 3 results
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  • 10.  水野 潤 (60386737)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
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