Izumi Masayuki 和泉雅之

… Alternative Names

IZUMI Masayuki 和泉雅之

和泉雅之イズミマサユキ

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Researcher Number	80332641
Other IDs	https://orcid.org/0000-0001-6486-9678
Affiliation (Current)	2025: 高知大学, 教育研究部総合科学系複合領域科学部門, 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 高知大学, 教育研究部総合科学系複合領域科学部門, 教授 2015: 大阪大学, 理学(系)研究科(研究院), 准教授 2014: 大阪大学, 理学(系)研究科(研究院), 講師 2013: 大阪大学, 理学研究科, 講師 2005 – 2006: 独立行政法人産業技術総合研究所, バイオニクス研究センター, 研究員 2002 – 2003: 東京工業大学, 大学院・生命理工学研究科, 助手
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Chemical biology / Bio-related chemistry / Bioorganic chemistry Except Principal Investigator Broad Section E / Medium-sized Section 37:Biomolecular chemistry and related fields / Applied molecular and cellular biology
Keywords	Principal Investigator ユビキチン / δ-セレノリシン / タンパク質化学合成 / セレン / 分解 / 糖タンパク質 / セレナゾリジン / セレノシステイン / リシン / 化学選択的縮合反応 … More / ジセレニド結合 / 環状セレノエステル / 変性糖タンパク質 / 分子プローブ / 脱セレノ化 / 連結反応 / 精密化学合成 / δ-メルカプトリシン / 固相合成 / フォールディング / δ-メルカプト-L-リジン / イソペプチド連結反応 / 高マンノース型糖鎖 / ユビキチン化 / 不良品糖タンパク質 / プロテアソーム / 糖鎖 / 分解経路 / 化学合成 / 中圧分取液体クロマトグラム / リン酸アナログ / ノニトールアナログ / C-エチルホスホン酸アナログ / 二基質結合型阻害剤 / HPLCアッセイ / N-アセチルラクトサミン / 蛍光ラベル / C-エチルホスホン酸エステル / CMP-シアル酸 / 二気質結合阻害剤 / 酵素阻害剤 / シアル酸転移酵素 … More Except Principal Investigator 糖鎖 / 糖鎖タグ / 水和 / 糖タンパク質 / 膜貫通型糖タンパク質 / CryoEM / 糖鎖水和殻 / 糖ペプチド / メルカプトアミノ酸 / チオアシッド / 水和水 / 糖水和 / タンパク質 / 揺らぎ / 膜糖タンパク質 / 水和殻 / エリスロポエチン / 小型糖タンパク質 / sensing / chip / Shiga toxins / carbohydrate / sugar / 生体機能利用 / ベロ毒素 / センシング / 有害蛋白質 / チップ Less

Sequential peptide ligation using spontaneous deprotection reaction by intramolecular seleniumPrincipal Investigator
- Principal Investigator
  
  和泉雅之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kochi University
ynthesis of modified protein using chemoselective ligation between d-selenolysine and selenoesterPrincipal Investigator
- Principal Investigator
  
  和泉雅之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kochi University
Evaluation of the effect of natural or unnatural glycosylation modes on the activity of glycoproteins
- Principal Investigator
  
  Kajihara Yasuhiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University
New Synthetic Methods for Glycoproteins and the Integrated Approaches to Elucidate the Functions of Post-translational Modifications
- Principal Investigator
  
  梶原康宏
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section E
- Research Institution
  Osaka University
Development of new synthetic method of ubiquitinated glycoprotein probe using specific reactivity of seleniumPrincipal Investigator
- Principal Investigator
  
  Izumi Masayuki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical biology
- Research Institution
  Kochi University
Total chemical synthesis of ubiquitinated glycoportein for the study of glycoprotein degradation processPrincipal Investigator
- Principal Investigator
  
  Izumi Masayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka University
Development of carbohydrate chipsfor high-sensitive analysis targeting biohazard proteins
- Principal Investigator
  
  UZAWA Hirotaka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  National Institute of Advanced Industrial Science and Technology (AIST)
複数基質を持つ酵素を阻害する-二基質結合型シアル酸転移酵素阻害剤の設計と開発Principal Investigator
- Principal Investigator
  
  和泉雅之
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Tokyo Institute of Technology

All 2024 2023 2022 2021 2020 2019 2018 2015 2005

All Journal Article Presentation

[Journal Article] Isopeptide bond formation mediated by δ-selenolysine for chemical ubiquitination2023
- Author(s)
  Akiyama Tatsunari, Tanaka Yusuke, Okamoto Ryo, Kajihara Yasuhiro, Izumi Masayuki
- Journal Title
  
  Frontiers in Chemistry
  
  Volume: 11 Pages: 1307254-1307254
- DOI
  10.3389/fchem.2023.1307254
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05311, KAKENHI-PROJECT-21H05028
[Journal Article] Isolation and characterization of high-mannose type glycans containing five or six mannose residues from hen egg yolk2022
- Author(s)
  Y. Maki, Y. Otani, R. Okamoto, M. Izumi, Y. Kajihara
- Journal Title
  
  Carbohydr. Res.
  
  Volume: 521 Pages: 108680-108680
- DOI
  10.1016/j.carres.2022.108680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H05028
[Journal Article] Chemical Synthesis of Ubiquitinated High-Mannose-Type N-Glycoprotein CCL1 in Different Folding States2020
- Author(s)
  Izumi Masayuki、Araki Hiroyuki、Tominaga Mamiko、Okamoto Ryo、Kajihara Yasuhiro
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 85 Issue: 24 Pages: 16024-16034
- DOI
  10.1021/acs.joc.0c01766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-17H02211
[Journal Article] Synthesis of polyanionic glycopolymers for the facile assembly of glycosyl arrays2005
- Author(s)
  Hirotaka Uzawa, Hiroki Ito, Masayuki Izumi, Hideo Tokuhisa, Kazuhiro Taguchi, Norihiko Minoura
- Journal Title
  
  Tetrahedron 61
  
  Pages: 5895-5905
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Presentation] チオエステルまたはセレノエステルを経由するペプチドヒドラジドのチオラクトンへのワンポット変換反応2024
- Author(s)
  船生悠貴、佐々木沙也佳、和泉雅之
- Organizer
  日本化学会第104春季年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05311
[Presentation] ハイマンノース型糖鎖を有するインターロイキン-8アナログの合成研究2024
- Author(s)
  赤山泰斗、菅野遥南、和泉雅之
- Organizer
  日化第104春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] ジセレニド結合を有するレクチンPhoSLアナログの化学合成2024
- Author(s)
  長島匡輝、和泉雅之
- Organizer
  日本化学会第104春季年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05311
[Presentation] セレナゾリジンを利用したレクチンPhoSLアナログの合成研究2023
- Author(s)
  長島匡輝、和泉雅之
- Organizer
  2023日本化学会中国四国支部大会山口大会
- Data Source
  KAKENHI-PROJECT-21K05311
[Presentation] コアフコース認識レクチンPhoSLのセレノシステイン置換体の合成研究2023
- Author(s)
  和泉雅之、長島匡輝
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21K05311
[Presentation] セレノシステインを含むレクチンPhoSL誘導体の合成研究2023
- Author(s)
  和泉雅之
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-21K05311
[Presentation] Chemical synthesis of an erythropoietin glycoform having a semisynthesized triantennary oligosaccharide and its biological evaluation2022
- Author(s)
  Yuta Maki, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara
- Organizer
  30th international carbohydrate symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18215
[Presentation] 環状ペプチドチオエステルの合成とその連結反応2022
- Author(s)
  中村佑介、赤井康人、藤坂優馬、和泉雅之
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K05311
[Presentation] 側鎖にオルソゴナルな保護基を有するδ-メルカプトリシン誘導体の合成2022
- Author(s)
  田村優伍、和泉雅之
- Organizer
  2022日本化学会中国四国支部大会
- Data Source
  KAKENHI-PROJECT-21K05311
[Presentation] hemical Synthesis of Diubiquitin using delta-selenolysine-mediated Ligation2021
- Author(s)
  秋山龍成、田中勇祐、岡本亮、梶原康宏、和泉雅之
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05311
[Presentation] Chemical synthesis of an erythropoietin glycoform having a semisynthesized triantennary oligosaccharide and its biological evaluation2021
- Author(s)
  Y. Maki, R. Okamoto, M. Izumi, Y. Kajihara
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Chemical synthesis of diubiquitin using delta-selenolysine-mediated ligation2021
- Author(s)
  Akiyama, Tatsunari; Tanaka, Yusuke; Okamoto, Ryo; Kajihara, Yasuhiro; Izumi, Masayuki
- Organizer
  Pacifichem2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02211
[Presentation] Nα-Boc-δ-セレノリシン誘導体の合成2021
- Author(s)
  田村優伍、和泉雅之
- Organizer
  2021日本化学会中国四国支部大会
- Data Source
  KAKENHI-PROJECT-21K05311
[Presentation] Chemical synthesis of an erythropoietin glycoform having a semisynthesized triantennary oligosaccharide and its biological evaluation2021
- Author(s)
  Yuta Maki, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18215
[Presentation] コアフコース認識レクチンPhoSL-ビオチンハイブリッドの化学合成2021
- Author(s)
  藤坂優馬、和泉雅之
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21K05311
[Presentation] Fmoc-δ-セレノリジン誘導体の合成法の改良2019
- Author(s)
  秋山龍成、和泉雅之
- Organizer
  高知化学シンポジウム2019
- Data Source
  KAKENHI-PROJECT-17H02211
[Presentation] ユビキチン化糖鎖化インターロイキン８の合成研究2019
- Author(s)
  ジョンソンエマリー、和泉雅之
- Organizer
  高知化学シンポジウム2019
- Data Source
  KAKENHI-PROJECT-17H02211
[Presentation] ペプチド固相合成に利用できる δ 位に置換基を有する D リジン誘導体の合成2019
- Author(s)
  秋山龍成、田中勇祐、岡本亮、梶原康宏、和泉雅之
- Organizer
  日本化学会第９９春季年会
- Data Source
  KAKENHI-PROJECT-17H02211
[Presentation] Selenoisopeptide Chemical Ligation toward Chemical Synthesis of Homogeneous Ubiquitinated Glycoprotein Containing Disufide Bond2018
- Author(s)
  Izumi, M., Tanaka, Y., Araki, H., Maki, Y., Okamoto, R., Kajihara, Y.
- Organizer
  29th International Carbohydrate Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02211
[Presentation] δ-セレノリジン誘導体を用いたユビキチン化糖タンパク質の合成研究2018
- Author(s)
  田中勇祐、真木勇太、岡本亮、梶原康宏、和泉雅之
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-17H02211
[Presentation] ユビキチン化された高マンノース型糖鎖を有する糖タンパク質CCL1の化学合成2015
- Author(s)
  和泉雅之、荒木浩行、冨永真美子、岡本亮、梶原康宏
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-25410175
[Presentation] Chemical synthesis of ubiquitinated glycoprotein CCL1 for analysis of glycoprotein degradation2015
- Author(s)
  Masayuki Izumi, Hiroyuki Araki, Mamiko Tominaga, Ryo Okamoto, Yasuhiro Kajihara
- Organizer
  The 13th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-13)
- Place of Presentation
  リーガロイヤルホテル（京都府京都市）
- Year and Date
  2015-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410175
[Presentation] Chemical synthesis of ubiquitinated glycoprotein having different protein conformation2015
- Author(s)
  Masayuki Izumi, Hiroyuki Araki, Mamiko Tominaga, Ryo Okamoto, Yasuhiro Kajihara
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (PACIFICHEM2015)
- Place of Presentation
  Hawaii Convention Center（米国ハワイ州ホノルル）
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410175
[Presentation] ユビキチン化タンパク質合成のためのC-末端活性化ユビキチンの化学合成2015
- Author(s)
  荒木浩行、和泉雅之、冨永真美子、岡本亮、梶原康宏
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学船橋キャンパス
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-25410175

1. KAJIHARA Yasuhiro (50275020)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. UZAWA Hirotaka (60356566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 松尾一郎 (40342852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 武田陽一 (20423973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 佐藤あやの (40303002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 川本晃大 (90631523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岡本亮 (30596870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 井原義人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Izumi Masayuki 和泉 雅之

IZUMI Masayuki 和泉 雅之

和泉 雅之 イズミ マサユキ

Research Projects

Research Products

Co-Researchers

Sequential peptide ligation using spontaneous deprotection reaction by intramolecular seleniumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ynthesis of modified protein using chemoselective ligation between d-selenolysine and selenoesterPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of the effect of natural or unnatural glycosylation modes on the activity of glycoproteins

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New Synthetic Methods for Glycoproteins and the Integrated Approaches to Elucidate the Functions of Post-translational Modifications

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new synthetic method of ubiquitinated glycoprotein probe using specific reactivity of seleniumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Total chemical synthesis of ubiquitinated glycoportein for the study of glycoprotein degradation processPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of carbohydrate chipsfor high-sensitive analysis targeting biohazard proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

複数基質を持つ酵素を阻害する-二基質結合型シアル酸転移酵素阻害剤の設計と開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Isopeptide bond formation mediated by δ-selenolysine for chemical ubiquitination2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolation and characterization of high-mannose type glycans containing five or six mannose residues from hen egg yolk2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemical Synthesis of Ubiquitinated High-Mannose-Type N-Glycoprotein CCL1 in Different Folding States2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis of polyanionic glycopolymers for the facile assembly of glycosyl arrays2005

Author(s)

Journal Title

Description

Data Source

[Presentation] チオエステルまたはセレノエステルを経由するペプチドヒドラジドのチオラクトンへのワンポット変換反応2024

Author(s)

Organizer

Data Source

[Presentation] ハイマンノース型糖鎖を有するインターロイキン-8アナログの合成研究2024

Author(s)

Izumi Masayuki 和泉雅之

IZUMI Masayuki 和泉雅之

和泉雅之イズミマサユキ

[Presentation] ペプチド固相合成に利用できる δ 位に置換基を有する D リジン誘導体の合成2019