SAKURAI Yoshihiko 櫻井嘉彦

Researcher Number	80347559
Other IDs	https://orcid.org/0000-0002-1773-5535
Affiliation (based on the past Project Information) *help	2007: Nara Medical University, School of Medicine, Assistant lecturer 2007: 奈良県立医科大学, 医科部, 助教 2004 – 2006: 奈良県立医科大学, 医学部, 助手 2004: Nara Medical University, Pediatrics, Lecturer, 医学部・小児科, 助手
Review Section/Research Field	Except Principal Investigator Pediatrics / Pediatrics
Keywords	Except Principal Investigator factor VIII / トロンビン生成 / 血友病A / 第VIII因子 / 血友病 / 凝固波形 / plasmin / clotting function / inactivation / activation … More / hemophilia A / thrombin generation / clot waveform analysis / 第IX因子 / 凝固加速度 / 凝固速度 / 血液凝固 / トロンビン / 止血モニタリング / 組織因子 / プラスミン / 凝固機能 / 不活性化 / 活性化 / hemophilia / Clot waveform / 遺伝子治療 Less

Study on the clotting function by clot waveform analysis
- Principal Investigator
  
  SHIMA Midori
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nara Medical University
In vitro study for clotting function aid activation mechanism in the gene therapy for haemophilia A
- Principal Investigator
  
  SHIMA Midori
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nara Medical University

All 2007 2006 2005 2004 2003 2002

All Journal Article Presentation

[Journal Article] Factor VIII-mediated global hemostasis in the absence of von Willebrand factor2007
- Author(s)
  Takeyama M, Kasuda S, Sakurai Y, Shima M, et. al.
- Journal Title
  
  International Journal of Hematology 85
  
  Pages: 397-402
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] Superficial fibromatosis mimicking subcutaneous hematoma : An unusual and difficult diagnosis in a patient with mild Hemophilia A2007
- Author(s)
  Sakurai Y, Shima M, et al.
- Journal Title
  
  International Journal of Hematology 85(1)
  
  Pages: 1-4
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] Heparin-induced inhibitory effects of a prothrombin complex concentrate on global tests of haemostasis2007
- Author(s)
  Takeyama M, Sakurai Y, Shima M, et. al.
- Journal Title
  
  Blood Coagulation & Fibrinolysis 18
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] Heparin-induced inhibitory effects of a prothrombin complex concentrate on global tests of haemostasis.2007
- Author(s)
  Takeyama M, Sakurai Y, Shima M, Yoshioka A, et. al.
- Journal Title
  
  Blood Coagulation & Fibrinolysis 18
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] Superficial fibromatosis mimicking subcutaneous hematoma:An unusual and difficult diagnosis in a patient with mild Hemophilia A.2007
- Author(s)
  Sakurai Y, Sugimoto H, Yoshida K, Shima M, et. al.
- Journal Title
  
  International Journal of Hematology,
  
  Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] Higher recovery of factor VIII (FVIII) with intermediate FVIII/von Willebrand factor concentrate than with recombinant FVIII in a haemophilia A patient with an inhibitor2006
- Author(s)
  T Inoue T, M Shima, M Takeyama, T Matsumoto, K Nishiya, I Tanaka, Y Sakurai, JC Giddings, A Yoshioka
- Journal Title
  
  Haemophilia 12
  
  Pages: 110-113
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] Successful use of recombinant factor VIII devoid of von Willebrand factor during multiple teeth extractions in a patient with type 3 von Willebrand disease2006
- Author(s)
  Sakurai Y, Shima M, et al.
- Journal Title
  
  Blood Coagulation and Fibrinolysis 17(2)
  
  Pages: 151-154
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] Successful use of recombinant factor VIII devoid of von Willebrand factor during multiple teeth extractions in a patient with type 3 von Willebrand disease2006
- Author(s)
  Sakurai Y, Shima M, Imai Y, et. al.
- Journal Title
  
  Blood Coagulation and Fibrinolysis 17
  
  Pages: 151-154
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] The measurement of low levels of factor VIII or factor IX in hemophilia A and hemophilia B plasma by clot waveform analysis and trombin generation assay2006
- Author(s)
  Matsumoto T, Shima M, Takeyama M, Yoshida K, Tanaka I, Sakurai Y, Giles AR, Yoshioka A.
- Journal Title
  
  Journal of Thrombosis and Haemostasis 4・2
  
  Pages: 377-384
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] Successful use of recombinant factor VIII devoid of von Willebrand factor during multiple teeth extractions in a patient with type 3 von Willebrand disease.2006
- Author(s)
  Sakurai Y, Shima M, Imai Y, et. al.
- Journal Title
  
  Blood Coagulation and Fibrinolysis 17
  
  Pages: 151-154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] Successful use of recombinant factor VIII devoid of von Willebrand factor during multiple teeth extractions in patient with type 3 von Willebrand disease2005
- Author(s)
  Y Sakurai, M Shima, Y Imai, A Omura, T Kirita, A Yoshioka
- Journal Title
  
  Blood Coagulation and Fibrinolysis 17
  
  Pages: 151-154
- Data Source
  KAKENHI-PROJECT-17591110
[Journal Article] A critical role for thrombin in platelet aggregation under high shear stress2004
- Author(s)
  Yoshihiko Sakurai, Midori Shima, Masahiro Takeyama et al.
- Journal Title
  
  Thrombosis Research 113
  
  Pages: 311-318
- Data Source
  KAKENHI-PROJECT-14570761
[Journal Article] Association of antiidiotypic antibodies with immune tolerance induction therapy for hemophilia A with inhibitors.2004
- Author(s)
  Yoshihiko Sakurai, Midori Shima, Ichiro Tanaka et al.
- Journal Title
  
  Hematologica 89
  
  Pages: 696-703
- Data Source
  KAKENHI-PROJECT-14570761
[Journal Article] Replacement therapy with plasma-derived factor VIII concentrates induces skew in T-cell receptor usage and clonal expansion of CD8+ T-cell in HIV-seronegative hemophilia patients.2003
- Author(s)
  Takaji Matsutani, Yoshihiko Sakurai, Takeshi Yoshioka, Yuji Tsuruta, Ryuji Suzuki, Midori Shima, Akira Yoshioka
- Journal Title
  
  Thrombosis and Haemostasis 90
  
  Pages: 279-292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570761
[Journal Article] Replacement therapy with plasma-derived factor VIII concentrates induces skew in T-cell receptor usage and clonal expansion of CD8^+ Tcell2003
- Author(s)
  Takaji Matsutani, Yoshihiko Sakurai, Midori Shima et al.
- Journal Title
  
  Thrombosis and Haemostasis 90
  
  Pages: 279-292
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570761
[Journal Article] A novel mechanism of factor VIII protection by von Willebrand factor from activated protein C-catalyzed inactivation.2002
- Author(s)
  Keiji Nogami, Midori Shima, Katsumi Nishiya, Kazuya Hosokawa, Evgueni L Saenko, Yoshihiko Sakurai, Masaru Shibata, Hiroshi Suzuki, Ichiro Tanaka, Akira Yoshioka
- Journal Title
  
  Blood 99
  
  Pages: 3993-3998
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570761
[Journal Article] Human factor VIII.inhibitor alloantibodies with a C2 epitope inhibit factor Xa-catalyzed factor VIII activation : a new anti-factor VIII inhibitory mechanism2002
- Author(s)
  Keiji Nogami, Midori Shima, Katsumi Nishiya, Hiroshi Suzuki, Yoshihiko Sakurai, Ichiro Tanaka, John C Giddings, Evgueni L Saenko, Akira Yoshioka
- Journal Title
  
  Thrombosis and Haemostasis 87
  
  Pages: 459-465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570761
[Presentation] ヒト第VIII因子発現マウスES細胞を用いた血友病A細胞療法2007
- Author(s)
  粕田承吾、櫻井嘉彦、嶋緑倫, 他
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  賢島
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-17591110
[Presentation] 凝固波形およびトロンビン生成試験を用いた蕁麻疹患者における凝固能の検討2007
- Author(s)
  櫻井嘉彦、竹田知広、嶋緑倫, 他
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  賢島
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-17591110

1. SHIMA Midori (30162663)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
2. TANAKA Ichiro (00201616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. KEIJI Nogami (50326328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAKURAI Yoshihiko 櫻井 嘉彦

Research Projects

Research Products

Co-Researchers

Study on the clotting function by clot waveform analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vitro study for clotting function aid activation mechanism in the gene therapy for haemophilia A

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Factor VIII-mediated global hemostasis in the absence of von Willebrand factor2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Superficial fibromatosis mimicking subcutaneous hematoma : An unusual and difficult diagnosis in a patient with mild Hemophilia A2007

Author(s)

Journal Title

Data Source

[Journal Article] Heparin-induced inhibitory effects of a prothrombin complex concentrate on global tests of haemostasis2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Heparin-induced inhibitory effects of a prothrombin complex concentrate on global tests of haemostasis.2007

Author(s)

Journal Title

Data Source

[Journal Article] Superficial fibromatosis mimicking subcutaneous hematoma:An unusual and difficult diagnosis in a patient with mild Hemophilia A.2007

Author(s)

Journal Title

Data Source

[Journal Article] Higher recovery of factor VIII (FVIII) with intermediate FVIII/von Willebrand factor concentrate than with recombinant FVIII in a haemophilia A patient with an inhibitor2006

Author(s)

Journal Title

Data Source

[Journal Article] Successful use of recombinant factor VIII devoid of von Willebrand factor during multiple teeth extractions in a patient with type 3 von Willebrand disease2006

Author(s)

Journal Title

Data Source

[Journal Article] Successful use of recombinant factor VIII devoid of von Willebrand factor during multiple teeth extractions in a patient with type 3 von Willebrand disease2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] The measurement of low levels of factor VIII or factor IX in hemophilia A and hemophilia B plasma by clot waveform analysis and trombin generation assay2006

Author(s)

Journal Title

Data Source

[Journal Article] Successful use of recombinant factor VIII devoid of von Willebrand factor during multiple teeth extractions in a patient with type 3 von Willebrand disease.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Successful use of recombinant factor VIII devoid of von Willebrand factor during multiple teeth extractions in patient with type 3 von Willebrand disease2005

Author(s)

Journal Title

Data Source

[Journal Article] A critical role for thrombin in platelet aggregation under high shear stress2004

Author(s)

Journal Title

Data Source

[Journal Article] Association of antiidiotypic antibodies with immune tolerance induction therapy for hemophilia A with inhibitors.2004

Author(s)

Journal Title

Data Source

[Journal Article] Replacement therapy with plasma-derived factor VIII concentrates induces skew in T-cell receptor usage and clonal expansion of CD8+ T-cell in HIV-seronegative hemophilia patients.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Replacement therapy with plasma-derived factor VIII concentrates induces skew in T-cell receptor usage and clonal expansion of CD8^+ Tcell2003

Author(s)

Journal Title

SAKURAI Yoshihiko 櫻井嘉彦