Hamaguchi Masahide 濱口真英

… Alternative Names

HAMAGUCHI Masahide 濱口真英

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Researcher Number	80350883
Other IDs	https://orcid.org/0000-0002-8651-4445
Affiliation (Current)	2024: 京都府立医科大学, 医学(系)研究科(研究院), 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2016 – 2017: 京都府立医科大学, 医学部附属病院, 研究員 2014 – 2015: 京都府立医科大学, 医学部附属病院, 専攻医 2014: 京都府立医科大学, 医学部附属病院, 研究員 2013: 大阪大学, 免疫学フロンティア研究センター, 特任助教 2011 – 2012: 大阪大学, 免疫学フロンティア研究センター, 特任研究員
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 58020:Hygiene and public health-related: including laboratory approach Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 53020:Cardiology-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 38050:Food sciences-related / Endocrinology / General surgery
Keywords	Principal Investigator 慢性炎症 / 制御性T細胞 / 非アルコール性脂肪肝炎 / 糖尿病 / 腸内環境 / 粒径 / 組成 / マイクロプラスチック / レプチン / T細胞 … More / 脂肪肝 / 自然炎症 / 自己免疫 / 免疫学 / 消化器内科学 / 非アルコール性脂肪肝疾患 / レプチン抵抗性 / インスリン抵抗性 / 非アルコール性脂肪疾患 … More Except Principal Investigator 糖尿病 / 悪化 / フレイル / メタボローム / microRNA / サルコペニア / 発生源 / 構成成分 / PM2.5 / マルチオミクス / 飽和脂肪酸 / サルコペニア肥満 / メタボローム解析 / 食塩過剰摂取 / 腸内菌叢 / 動脈硬化 / メカニズム / アレルギー / 経口曝露 / マイクロプラスチック / エピゲノム / エピジェネティック制御 / 中鎖脂肪酸 / let-7 / 水溶性食物繊維 / 腸管上皮幹細胞 / アンドロゲン / ポリアミン / スペルミジン / スペルミン / Testosterone / Androgen / Metabolic syndrome / Glucose metabolism / Diabetes / Muscle atrophy / Sarcopenia / 皮下移植 / 移植 / 血糖値 / 制御性T細胞 / 膵島 / ランゲルハンス氏島 Less

Regulation of intestinal-stem-cell function by metabolites derived from fermentation of soluble dietary fiber
- Principal Investigator
  
  中西尚子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Kyoto Prefectural University of Medicine
Composition, particle size and health effects of microplastics with focus on intestinal environment and diabetesPrincipal Investigator
- Principal Investigator
  
  濱口真英
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
Investigation of improvement of skeletal muscle function by RNA interference for prevention of frailty
- Principal Investigator
  
  岡田博史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyoto Prefectural University of Medicine
Medium Chain Fatty Acids for Frail Prevention and Epigenetic Regulation
- Principal Investigator
  
  福井道明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyoto Prefectural University of Medicine
マイクロプラスチックの経口曝露によるアレルギーの悪化とメカニズムの解明
- Principal Investigator
  
  高野裕久
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto University of Advanced Science
一般環境中のPM2.5による糖尿病発症、悪化メカニズムの解明
- Principal Investigator
  
  高野裕久
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto University of Advanced Science
Mechanism of atherosclerosis progression via increased absorption of saturated fatty acids due to excessive salt intake
- Principal Investigator
  
  牛込恵美 (白石恵美)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Mechanisms of Metabolic and Signaling Disorders Induced by Saturated Fatty Acids in Skeletal Muscle
- Principal Investigator
  
  千丸貴史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyoto Prefectural University of Medicine
The molecular mechanism of sarcopenia associated with male menopause
- Principal Investigator
  
  Fukui Michiaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Kyoto Prefectural University of Medicine
Transplantation of islets in immune tolerance site under skin induced by bFGF or SEK-1005
- Principal Investigator
  
  IWATA Hiroo
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
制御性T細胞の強化による非アルコール性脂肪肝炎制御の実現とその免疫学的機構の解明Principal Investigator
- Principal Investigator
  
  濱口真英
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
Steatohepatitis as altered immune metabolism by Regulatory T cellPrincipal Investigator
- Principal Investigator
  
  HAMAGUCHI Masahide
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University

All 2015 2014 2013 2012 Other

All Journal Article Presentation Book Patent

[Book] リウマチ科第50巻第2号特集/感染症に伴う関節症の診断と治療解説制御性T細胞による免疫応答制御大阪大学免疫学フロンティア研究センター実験免疫学2013
- Author(s)
  濱口真英坂口志文
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23790791
[Book] 標準免疫学第3版第7章ホメオスタシス維持のメカニズム191-205 大阪大学免疫学フロンティア研究センター実験免疫学
- Author(s)
  執筆協力者濱口真英
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] The modest alcohol consumption reduces the incidence of fatty liver in men: a population-based large-scale cohort study2015
- Author(s)
  Yoshitaka Hashimoto, Masahide Hamaguchi, Takao Kojima, Yasuhiro Ohshima Akihiro Ohbora, Takahiro Kato, Naoto Nakamura, Michiaki Fukui
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 30 Issue: 3 Pages: 546-552
- DOI
  10.1111/jgh.12786
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860502
[Journal Article] Association between serum γ-glutamyltranspeptidase and atherosclerosis: a population-based cross-sectional study2014
- Author(s)
  Takuya Fukuda, Masahide Hamaguchi, Takao Kojima, Yasuhiro Ohshima, Akihiro Ohbora, Takahiro Kato, Naoto Nakamura, Michiaki Fukui
- Journal Title
  
  BMJ open
  
  Volume: 4 Issue: 10 Pages: e005413-e005413
- DOI
  10.1136/bmjopen-2014-005413
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860502
[Journal Article] An atlas of active enhancers across human cell types and tissues.2014
- Author(s)
  Anderson R, Gebhard C, Miguel-Escalada I, Hoof I, Bornholdt J, Boyd M, Chen Y, Zhao X, Schmidl C, Suzuki T, Collaborators(261) Enomoto H, etc.
- Journal Title
  
  Nature
  
  Volume: 507 Issue: 7493 Pages: 455-461
- DOI
  10.1038/nature12787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22122005, KAKENHI-PROJECT-22228005, KAKENHI-PROJECT-23790791, KAKENHI-PROJECT-24659373, KAKENHI-PUBLICLY-25118732, KAKENHI-PROJECT-25330333
[Journal Article] Favorable effect of modest alcohol consumption to fatty liver disease.2013
- Author(s)
  Hamaguchi M, Kojima T
- Journal Title
  
  World J Gastroenterol
  
  Volume: 19 Issue: 32 Pages: 5393-4
- DOI
  10.3748/wjg.v19.i32.5393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] Diabetes and Colorectal Cancer2012
- Author(s)
  Hamaguchi, Masahide, Takao Kojima, and Takahiro Kato
- Journal Title
  
  Nihon rinsho
  
  Volume: 70 Suppl 5 Pages: 573-577
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] Association between Bright Pancreas and Features of Metabolic Syndrome2012
- Author(s)
  Akihiro Ohbora, Takao Kojima, Takahiro Kato, Mio Endo, Kiichiro Miyawaki, Nobuhiro Fukuta, Naomi Ban, Masahide Hamaguchi
- Journal Title
  
  Ningen Dock
  
  Volume: 26（6） Pages: 935-943
- NAID
  10031145832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] Identification of individuals with non-alcoholic fatty liver disease by the diagnostic criteria for the metabolic syndrome.2012
- Author(s)
  Hamaguchi M, Takeda N, Kojima T, Ohbora A, Kato T, Sarui H, Fukui M, Nagata C, Takeda J.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 13 Pages: 1508-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] Protective effect of alcohol consumption for fatty liver but not metabolic syndrom2012
- Author(s)
  kui,Takahiro Kato
- Journal Title
  
  World of Gastroenterology
  
  Volume: 18(2) Issue: 2 Pages: 156-167
- DOI
  10.3748/wjg.v18.i2.156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] Protective effect of alcohol consumption for fatty liver but not metabolic syndrome.2012
- Author(s)
  Hamaguchi M, Kojima T, Ohbora A, Takeda N, Fukui M, Kato T.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 2 Pages: 156-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] Aging is a risk factor of nonalcoholic fatty liver disease in premenopausal women.2012
- Author(s)
  Hamaguchi M, Kojima T, Ohbora A, Takeda N, Fukui M, Kato T.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 3 Pages: 237-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] Aging is a risk factor of nonalcoholic fatty liver disease in premenopausal women2012
- Author(s)
  Hamaguchi M, Kojima T, Ohbora A, Takeda N, Fukui M, Kato T
- Journal Title
  
  World J Gastroenterol
  
  Volume: 18(3) Issue: 3 Pages: 237-43
- DOI
  10.3748/wjg.v18.i3.237
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] Identification of individuals with non-alcoholic fatty liver disease by the diagnostic criteria for the metabolic syndrome2012
- Author(s)
  Hamaguchi M, Takeda N, Kojima T, Ohbora A, Kato T, Sarui H, Fukui M, Nagata C, Takeda J
- Journal Title
  
  World J Gastroenterol
  
  Volume: 18(13) Issue: 13 Pages: 1508-16
- DOI
  10.3748/wjg.v18.i13.1508
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] Regulatory T Cells Expressing PPAR-γ Control Inflammation in Obesity.2012
- Author(s)
  Hamaguchi, Masahide, and Shimon Sakaguchi
- Journal Title
  
  Cell metabolism
  
  Volume: 16 Issue: 1 Pages: 4-6
- DOI
  10.1016/j.cmet.2012.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] Diabetes and colorectal cancer2012
- Author(s)
  Hamaguchi M, Kojima T, Kato T
- Journal Title
  
  Nihon Rinsho
  
  Volume: Suppl 5 Pages: 573-7
- Data Source
  KAKENHI-PROJECT-23790791
[Journal Article] T cell receptor stimulation-induced epi genetic changes and Foxp3 expression are independent and complementary events required for Treg cell development2012
- Author(s)
  大倉永也
- Journal Title
  
  Immunity
  
  Volume: 37 Issue: 5 Pages: 785-799
- DOI
  10.1016/j.immuni.2012.09.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03737, KAKENHI-PROJECT-21590533, KAKENHI-PROJECT-23790791
[Patent] 脂肪肝疾患の患者の検査方法2015
- Inventor(s)
  濱口真英、中村直登、伊藤義人、西川博嘉、坂口志文
- Industrial Property Rights Holder
  濱口真英、中村直登、伊藤義人、西川博嘉、坂口志文
- Industrial Property Rights Type
  特許
- Filing Date
  2015-03-06
- Data Source
  KAKENHI-PROJECT-26860502
[Presentation] テストステロン低下と慢性炎症により惹起されるサルコペニアを伴った非アルコール性脂肪肝炎の病態解明2015
- Author(s)
  千丸貴史、濱口真英、福田拓也、木村寿宏、橋本善隆、北川功幸、三橋一輝、田中武兵、浅野麻衣、山崎真裕、中村直登、福井道明
- Organizer
  第2回肝臓と糖尿病・代謝研究会
- Place of Presentation
  下関、山口、海峡メッセ下関
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15K09441
[Presentation] 大規模コホート研究NAGALA による過体重よりまさる糖尿病発症リスクとしての非アルコール性脂肪性肝疾患（NAFLD）2015
- Author(s)
  福田拓也、濱口真英、小島孝雄、大島靖広、大洞昭博、加藤隆弘、福井道明、中村直登
- Organizer
  第2回　肝臓と糖尿病代謝研究会
- Place of Presentation
  山口
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26860502
[Presentation] 高レプチン環境による制御性T細胞の機能低下と脂肪肝炎2015
- Author(s)
  濱口真英、島津裕、高折晃史、角田圭雄、山口寛二、西川博嘉、福井道明、伊藤義人、中村直登
- Organizer
  第2回　肝臓と糖尿病代謝研究会
- Place of Presentation
  山口
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26860502
[Presentation] 東京制御性T細胞減弱による代謝免疫学的非アルコール性脂肪肝炎(NASH)モデルマウスの解析2014
- Author(s)
  濱口真英、島津裕、高折晃史、角田圭雄、山口寛二、西川博嘉、福井道明、坂口志文、伊藤義人、中村直登
- Organizer
  第1回肝臓と糖尿病・代謝研究会
- Place of Presentation
  東京
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-23790791
[Presentation] 制御性T細胞減弱による代謝免疫学的非アルコール性脂肪肝炎(NASH)モデルマウスの解析2014
- Author(s)
  濱口真英、島津裕、高折晃史、角田圭雄、山口寛二、西川博嘉、福井道明、坂口志文、伊藤義人、中村直登
- Organizer
  第1回　肝臓と糖尿病代謝研究会
- Place of Presentation
  東京
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-26860502
[Presentation] Essential role for BCL11b in the FoxP3 transcriptional complex and T regulatory cells suppressive function2013
- Author(s)
  Masahide Hamaguchi, Kaoru Sakai, Naganari Ohkura, Hiromasa Morikawa, Yutaka Shimazu, James Badger Wing, Shimon Sakaguchi
- Organizer
  国際免疫学会
- Place of Presentation
  ミラノ、イタリア
- Data Source
  KAKENHI-PROJECT-23790791
[Presentation] Constitution of the Foxp3 complex: key association of Bcl11b to CTLA-4 dependent Treg supressive function
- Author(s)
  Masahide Hamaguchi, Kaoru Sakai, Naganari Ohkura, Hiromasa Morikawa1, Yutaka Shimazu1, Hans Joerg Fehling, Tim Sparwasser, Tetsuya Hirose, Ryo KominamiShimon Sakaguchi
- Organizer
  The 2nd NIF Winter School on Advanced Immunology
- Place of Presentation
  Singapore, Amara Sanctury resort
- Data Source
  KAKENHI-PROJECT-23790791
[Presentation] 大規模コホート研究 NAGALA による非肥満者からの糖尿病発症リスクとしての非アルコール性脂肪性肝疾患
- Author(s)
  福田拓也, 濱口真英, 小島孝雄, 大島靖広, 大洞昭博, 加藤隆弘, 中村直登, 福井道明
- Organizer
  第112回日本内科学会講演会
- Place of Presentation
  京都
- Year and Date
  2015-04-10 – 2015-04-12
- Data Source
  KAKENHI-PROJECT-26860502
[Presentation] 岐阜における非アルコール性脂肪肝NAFLDの経時的コホート研究
- Author(s)
  濱口真英、小島孝雄、大洞昭博
- Organizer
  NAGALA (NAFLD in Gifu Area, Longitudinal Analysis) study
- Data Source
  KAKENHI-PROJECT-23790791
[Presentation] 制御性T細胞減弱による代謝免疫学的非アルコール性脂肪肝炎(NASH)モデルマウスの解析
- Author(s)
  濱口真英、島津裕、高折晃史、角田圭雄、山口寛二、西川博嘉、福井道明、坂口志文、伊藤義人、中村直登
- Organizer
  第1回肝臓と糖尿病・代謝研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790791
[Presentation] Transcriptional complexes containing Foxp3 and Bcl11b control Treg supressive function
- Author(s)
  Masahide Hamaguchi, Kaoru Sakai, Naganari Ohkura, Hiromasa Morikawa1, Yutaka Shimazu1, Shimon Sakaguchi
- Organizer
  日本免疫学会総会
- Place of Presentation
  神戸市神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23790791
[Presentation] 非飲酒女性での血清gamma-glutamyltransepeptidase (GGT)値上昇は動脈硬化リスクである
- Author(s)
  濱口真英、小島孝雄、大洞昭博、渡邊一敏、中村清、出口冨美子、福田拓也、福井道明、中村直登
- Organizer
  第43回総合健診医学会
- Place of Presentation
  富山
- Year and Date
  2015-02-20 – 2015-02-21
- Data Source
  KAKENHI-PROJECT-26860502

1. Fukui Michiaki (30247829)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
2. 高野裕久 (60281698)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 中西尚子 (40843446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 岡村拓郎 (00885163)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. IWATA Hiroo (30160120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAKAGUCHI Shimon (30280770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山崎真裕 (50309134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 田中武兵 (70713717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 岡田博史 (30806831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 牛込恵美 (80440890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 千丸貴史 (20637889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 奥田知明 (30348809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ENOMOTO Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hamaguchi Masahide 濱口 真英

HAMAGUCHI Masahide 濱口 真英

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制御性T細胞の強化による非アルコール性脂肪肝炎制御の実現とその免疫学的機構の解明Principal Investigator

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Steatohepatitis as altered immune metabolism by Regulatory T cellPrincipal Investigator

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[Book] リウマチ科第50巻第2号 特集/感染症に伴う関節症の診断と治療解説制御性T細胞による免疫応答制御 大阪大学免疫学フロンティア研究センター実験免疫学2013

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[Book] 標準免疫学第3版第7章 ホメオスタシス維持のメカニズム191-205 大阪大学免疫学フロンティア研究センター実験免疫学

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[Journal Article] The modest alcohol consumption reduces the incidence of fatty liver in men: a population-based large-scale cohort study2015

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Hamaguchi Masahide 濱口真英

HAMAGUCHI Masahide 濱口真英

[Book] リウマチ科第50巻第2号特集/感染症に伴う関節症の診断と治療解説制御性T細胞による免疫応答制御大阪大学免疫学フロンティア研究センター実験免疫学2013

[Book] 標準免疫学第3版第7章ホメオスタシス維持のメカニズム191-205 大阪大学免疫学フロンティア研究センター実験免疫学