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Kimura Shinya  木村 晋也

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… Alternative Names

KIMURA Shinya  木村 晋也

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Researcher Number 80359794
External Links
Affiliation (Current) 2025: 佐賀大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2013 – 2024: 佐賀大学, 医学部, 教授
2013: 佐賀大学, 医学部, 教授研究者
2009 – 2011: Saga University, 医学部, 教授
2008: 京都大学, 大学院・医学研究科, 助教
2007 – 2008: Kyoto University, Dep. of Transfusion Medicne and Cell Therapy, Assistant Professor
2003 – 2006: 京都大学, 医学研究科, 助手
Review Section/Research Field
Principal Investigator
Hematology / Basic Section 54010:Hematology and medical oncology-related / Laboratory medicine
Except Principal Investigator
Hematology / Orthopaedic surgery / Basic Section 58060:Clinical nursing-related / Basic Section 52010:General internal medicine-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 47060:Clinical pharmacy-related / Basic Section 49030:Experimental pathology-related … More / Tumor diagnostics / Medical pharmacy / Chemistry related to living body / Urology / Biological Sciences Less
Keywords
Principal Investigator
慢性骨髄性白血病 / 白血病 / 免疫 / 無治療寛解 / メチル化 / チロシンキナーゼ / ABL / Ras / zoledronate / γδT細胞 … More / YM529 / p53 / ビスフォスフォネート / 幹細胞 / ナノチャンバー / 破骨細胞 / ニッチ / メチル化阻害剤 / 治療不要寛解 / バイオマーカー / NK 細胞 / NK 免疫 / チロシンキナーゼ阻害剤 / Niche / γδTcell / osteoclast / leukemia / bisphosphonate / γδ T細胞 / γδ T cell / p-glycoprotein / imatinib mesykate / bisphosphonates / RAS related proteins / imatinib mysylate / imatinib mesylate / Zoledronate / BCR-ABL / RAS / 分子標的 / P糖蛋白 / イマチニブ / ゾレドロン酸 / RAS関連蛋白質 / HIF-1α / BMI-1 / シクロデキストリン / 低酸素 / ABLチロシンキナーゼ / 骨芽細胞 / 骨 / 抗HLA抗体 / 抗顆粒球抗体 / 輸血後関連急性肺障害 / ABO血液型抗体 / 輸血検査 / 表面プラズモン共鳴 … More
Except Principal Investigator
分子標的治療 / アポトーシス / 白血病 / がん / シクロデキストリン / ビスホスホネート / 幹細胞 / ビスホスフォネート / 分子標的 / 慢性骨髄性白血病 / RNA干渉 / チロシンキナーゼ阻害剤 / 化学療法に関連した認知機能障害 / AYA世代がんサバイバー / 就労 / AYA世代 / 認知機能障害 / 化学療法 / シングルセル解析 / 内在性レトロウイルス / BCL-2 / DNAメチル化 / 急性骨髄性白血病 / オートファジー / 環状オリゴ糖 / 休薬判断 / 周術期 / 周術期休薬判断 / 機械学習 / 人工知能 / オミクス解析 / マルチオミクス / 全ゲノム / エンハンサー / 全ゲノム解析 / 有毛細胞白血病 / mouse model / metastasis / plasma DNA / EGFR T790M / mouse model / metastasis / plasma DNA / EGFR T790M / 血漿DNA / バイオマーカー / リキッドバイオプシー / ザラコジン酸 / イソプレン / エピカテキンガレート / がんバイオマーカー / 肺がん / イソプレノイド / 肺ガン / ポリフェノール / ヘッドスペースGC-FID / ザラゴジン酸 / イソプレノイド化合物 / LC-MS/MS / ファルネシルピロリン酸 / 移植片対宿主病(GVHD) / 移植片対腫瘍効果 / 免疫抑制剤 / MEK阻害剤 / 抗ウイルス免疫 / 抗腫瘍免疫 / 移植片対宿主病 / 造血幹細胞移植 / マウス移植モデル / 悪性腫瘍 / 細胞周期停止 / 脂質ラフト / コレステロール / 抗腫瘍薬 / 血液腫瘍学 / 骨肉腫 / 放射線治療 / 軟部肉腫 / Glyoxalase-I / T315I遺伝子 / オーロラキナーゼ阻害剤 / 白血病幹細胞 / 低酸素環境 / 低酸素 / 慢性骨髄白血病 / 治療抵抗性 / 遺伝子治療 / ピレン / 蛍光核酸プローブ / 遺伝子診断 / 蛋白質 / 細胞・組織 / バイオテクノロジー / 核酸 / 遺伝子 / 悪性軟部腫 / 癌 / 悪性軟部腫瘍 / 悪性骨腫瘍 / CD138 / β-catenin / siRNA / 多発性骨髄腫 / 分子標的療法 / フィラデルフィア染色体 / イマチニブ耐性 / Lyn / Bcr-Abl / 破骨細胞 / 点突然変異 / 中枢神経性白血病 / NS-187 / BCR-ABL / 耐性 / Bafetinib / Imatinib / BCR-ABL分子標的治療 / 遺伝子変異 / パフェチニブ / INNO-406 / イマチニブ / マウス / 経尿道的治療 / 膀胱癌 / small interfering RNA (siRNA) / polo like kinase (PLK)-1 / p53 / カスパーゼ / クマリン / GUT-70 / 天然化合物 / 3環系クマリン / おとぎり草 / 分子標的治療薬 / トランスレーショナル・リサーチ / ビスフォスフォネート / RAS関連蛋白 Less
  • Research Projects

    (26 results)
  • Research Products

    (323 results)
  • Co-Researchers

    (61 People)
  •  Development of a novel therapeutic strategy for leukemia by inducing autophagy with cyclodextrins.

    • Principal Investigator
      久保田 寧
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      SAGA-KEN MEDICAL CENTRE KOSEIKAN
  •  慢性骨髄性白血病の治療不要寛解率を向上させる治療法の開発Principal Investigator

    • Principal Investigator
      木村 晋也
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Saga University
  •  人工知能機械学習を応用した高精度周術期休薬判断アルゴリズムの構築

    • Principal Investigator
      木村 早希子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Saga University
  •  難治性白血病の内在性レトロウイルス活性化機序に基づく新規バイオマーカー開発

    • Principal Investigator
      田部 陽子
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Juntendo University
  •  whole genome and multiomics analysis of hairy cell leukemia japansese variant

    • Principal Investigator
      YOKOYAMA KAZUAKI
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      The University of Tokyo
  •  CRCI and its impact on employment outcomes in AYA cancer survivors

    • Principal Investigator
      Miyashita Mika
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58060:Clinical nursing-related
    • Research Institution
      Kyoto University
      Hiroshima University
  •  Development of new drugs and elucidation of immunity to cure all chronic myeloid leukemia patientsPrincipal Investigator

    • Principal Investigator
      Kimura Shinya
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Saga University
  •  Exploring biomarkers concerning NK immunity that favor treatment discontinuation in CML patientsPrincipal Investigator

    • Principal Investigator
      Kimura Shinya
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Saga University
  •  MEK inhibitors selectively suppress GVHD while sparing antitumor and antiviral immunity after allogeneic hematopoietic stem cell transplantation

    • Principal Investigator
      Shindo Takero
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kyoto University
      Saga University
  •  Analysis how circulating plasma DNA release to peripheral blood and that applies to metastatic animal model using human lung cancer cells

    • Principal Investigator
      Aragane Naoko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Saga University
  •  Identification and control of factors which regulate CML stem cellsPrincipal Investigator

    • Principal Investigator
      Kimura Shinya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Saga University
  •  Anticancer effect of 2-Hydroxypropyl-beta-cyclodextrin

    • Principal Investigator
      KUBOTA Yasushi
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Saga University
  •  Analytical development for determination of isoprenoid compounds in human plasma and usefulness as a new target of anti-cancer drugs

    • Principal Investigator
      Nakagawa Saori
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nigata University of Phermacy and Applied Life Sciences
  •  Development of new treatments against malignant bone and soft tissue tumors by using bisphosphonate and ionizing radiation

    • Principal Investigator
      MURATA Hiroaki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of novel functional oligonucleotide analogs for detection and regulation of a single base alteration in gene

    • Principal Investigator
      MURAKAMI Akira
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemistry related to living body
    • Research Institution
      Kyoto Institute of Technology
  •  Eradication of chronic myelogenous leukemia stem cells and abnormal clone with T315I point mutation

    • Principal Investigator
      MAEKAWA Taira
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kyoto University
  •  Influence of bone related cells on leukemic cellsPrincipal Investigator

    • Principal Investigator
      KIMURA Shinya
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Saga University
  •  Development of antibody-conjugatedβ-catenin siRNA therapy against multiple myeloma

    • Principal Investigator
      ASHIHARA Eishi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kyoto University
  •  Treatment using bisphosphonate for malignant bone and soft tissue tumors

    • Principal Investigator
      MURATA Hiroaki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Molecular therapeutics for imatinib-resistant Ph-positive leukemias with newly developed Bcr-Abl/Lyn tyrosine kinase inhibitor

    • Principal Investigator
      MAEKAWA Taira
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kyoto University
  •  Development ofa novel therapy for leukemia utilizing bisphcephonate trianglePrincipal Investigator

    • Principal Investigator
      KIMURA Shinya
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kyoto University
  •  表面プラズモン共鳴による革新的な輸血関連検査法の開発Principal Investigator

    • Principal Investigator
      木村 晋也
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Kyoto University
  •  ブラジル・おとぎり草から抽出した新規天然有機化合物(GUT-70)の抗腫瘍効果

    • Principal Investigator
      前川 平
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kyoto University
  •  PLK-1siRNAを用いた膀胱癌に対するあたらしい分子標的治療法の開発

    • Principal Investigator
      湯浅 健
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Kyoto University
  •  多剤耐性白血病に対するあらたな分子標的治療法の開発

    • Principal Investigator
      MAEKAWA Taira
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Targeting RAS for leukemia therapyPrincipal Investigator

    • Principal Investigator
      KIMURA Shinya
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kyoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] 今日の治療指針2023年度版2023

    • Author(s)
      木村晋也
    • Total Pages
      2119
    • Publisher
      神陵文庫
    • ISBN
      9784260050340
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Book] EBM 血液疾患. 2023-20242022

    • Author(s)
      木村晋也
    • Total Pages
      574
    • Publisher
      中外医学社
    • ISBN
      4498225406
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Book] 秒進分歩する癌研究の最前線.実験医学増刊2011

    • Author(s)
      木村晋也
    • Total Pages
      8
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-21591201
  • [Book] 秒進分歩する癌研究の最前線.実験医学増刊(分担執筆)2011

    • Author(s)
      木村晋也
    • Total Pages
      8
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-21591201
  • [Book] がん骨転移治療(分担執筆)2011

    • Author(s)
      福島伯泰、木村晋也
    • Total Pages
      7
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-21591201
  • [Book] がん骨転移治療2011

    • Author(s)
      福島伯泰、木村晋也
    • Total Pages
      7
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-21591201
  • [Book] 造血腫瘍アトラス2009

    • Author(s)
      木村晋也
    • Total Pages
      5
    • Publisher
      日本医事新報社
    • Data Source
      KAKENHI-PROJECT-21591201
  • [Book] がんの分子標的治療(鶴尾隆)(編集)(シグナル伝達系阻害剤)2008

    • Author(s)
      前川平、芦原英司、木村晋也
    • Publisher
      南山堂、東京
    • Data Source
      KAKENHI-PROJECT-18390283
  • [Book] 医学のあゆみ2008

    • Author(s)
      木村 晋也
    • Total Pages
      6
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Book] Bone Marrow Transplantaion : New research2006

    • Author(s)
      Kimura S
    • Total Pages
      165
    • Publisher
      Nova Publisher
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Book] イマチニブ以後の白血病に対する分子標的療法薬(高久史磨、溝口秀昭、坂田洋一、金倉譲、小島勢二)(編集)(Annual Review血液2006)2006

    • Author(s)
      木村晋也、前川平
    • Data Source
      KAKENHI-PROJECT-18390283
  • [Book] Bone Marrow Transplantation: New Research2006

    • Author(s)
      Kimura S
    • Total Pages
      38
    • Publisher
      New York: Nova Publisher
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Book] Annual Review血液2006

    • Author(s)
      木村晋也
    • Total Pages
      15
    • Publisher
      中外医学社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Book] Stem cell transplantation for Ph+ leukemias in the imatinib and post-imatinib eras. In, "Bone Marrow Transplantation : New Research."2006

    • Author(s)
      Kimura S, et al.
    • Total Pages
      165
    • Publisher
      Nova Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-18390283
  • [Book] Bone Marrow Transplantation : New Research(ed. By Davidson DF)(Stem cell transplantation for Ph+ leukemias in the imatinib and post-imatinib eras. In)2006

    • Author(s)
      Kimura, S., Maekawa, T.
    • Publisher
      Nova Science Publishers, Inc. reviewNova Science Publishers, Inc. review
    • Data Source
      KAKENHI-PROJECT-18390283
  • [Book] Annual Review 血液 20052005

    • Author(s)
      木村晋也
    • Total Pages
      308
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-16659254
  • [Book] 血液疾患のEBM (慢性骨髄性白血病の項目を担当)2004

    • Author(s)
      木村晋也
    • Total Pages
      11
    • Publisher
      メディカルレビュー社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591005
  • [Book] 血液疾患のEBM(慢性骨髄性白血病の項目を担当)2004

    • Author(s)
      木村晋也
    • Total Pages
      11
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-15591005
  • [Journal Article] Development of a specific and sensitive sandwich enzyme-linked immunosorbent assay for the quantification of dasatinib2023

    • Author(s)
      Kataoka Hiroto、Saita Tetsuya、Yamamoto Yuta、Sogawa Rintaro、Kimura Sakiko、Kimura Shinya、Shimanoe Chisato
    • Journal Title

      Analytical Biochemistry

      Volume: 678 Pages: 115272-115272

    • DOI

      10.1016/j.ab.2023.115272

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06769
  • [Journal Article] Localization of Sites of Osimertinib Action in Rat Intestine, Skin, and Lung by Immunohistochemistry2023

    • Author(s)
      Yamamoto Yuta、Saita Tetsuya、Kataoka Hiroto、Sogawa Rintaro、Kimura Sakiko、Kimura Shinya、Shimanoe Chisato、Shin Masashi
    • Journal Title

      ACTA HISTOCHEMICA ET CYTOCHEMICA

      Volume: 56 Issue: 6 Pages: 145-151

    • DOI

      10.1267/ahc.23-00055

    • ISSN
      0044-5991, 1347-5800
    • Year and Date
      2023-12-28
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06769
  • [Journal Article] Dual targeting of aberrant DNA and histone methylation synergistically suppresses tumor cell growth in ATL2023

    • Author(s)
      Kurahashi Yuki、Watanabe Tatsuro、Yamamoto Yuta、Ureshino Hiroshi、Kamachi Kazuharu、Yoshida-Sakai Nao、Fukuda-Kurahashi Yuki、Yamashita Satoshi、Hattori Naoko、Nakamura Hideaki、Kawaguchi Atsushi、Ushijima Toshikazu、Sueoka Eisaburo、Kimura Shinya
    • Journal Title

      Blood Advances

      Volume: 7 Issue: 8 Pages: 1545-1559

    • DOI

      10.1182/bloodadvances.2022008362

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K16245, KAKENHI-PROJECT-20K07593, KAKENHI-PROJECT-20K08756
  • [Journal Article] Targeting DNMT1 by demethylating agent OR-2100 increases tyrosine kinase inhibitors-sensitivity and depletes leukemic stem cells in chronic myeloid leukemia2022

    • Author(s)
      Kamachi Kazuharu、Ureshino Hiroshi、Watanabe Tatsuro、Yoshida Nao、Yamamoto Yuta、Kurahashi Yuki、Fukuda-Kurahashi Yuki、Hayashi Yoshihiro、Hirai Hideyo、Yamashita Satoshi、Ushijima Toshikazu、Okada Seiji、Kimura Shinya
    • Journal Title

      Cancer Letters

      Volume: 526 Pages: 273-283

    • DOI

      10.1016/j.canlet.2021.11.032

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07593, KAKENHI-PROJECT-21K16245, KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-21H02956
  • [Journal Article] Higher neutrophil counts are associated with successful tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia2022

    • Author(s)
      Ureshino Hiroshi、Kamachi Kazuharu、Sano Haruhiko、Okamoto Sho、Itamura Hidekazu、Yoshimura Mariko、Katsuya Hiroo、Ando Toshihiko、Kimura Shinya
    • Journal Title

      Hematology

      Volume: 27 Issue: 1 Pages: 1171-1175

    • DOI

      10.1080/16078454.2022.2135857

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K16245, KAKENHI-PROJECT-20K08756
  • [Journal Article] Favorable HLA Polymorphisms are Associated with Lower Molecular Relapse after Tyrosine Kinase Discontinuation in Patients with Chronic Myeloid Leukemia2022

    • Author(s)
      Ureshino Hiroshi、Kamachi Kazuharu、Shindo Takero、Kimura Shinya
    • Journal Title

      Indian Journal of Hematology and Blood Transfusion

      Volume: - Issue: 4 Pages: 760-761

    • DOI

      10.1007/s12288-022-01538-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08812, KAKENHI-PROJECT-20K08756
  • [Journal Article] Low-dose dasatinib in older patients with chronic myeloid leukaemia in chronic phase (DAVLEC): a single-arm, multicentre, phase 2 trial2021

    • Author(s)
      Murai K, Ureshino H, Kumagai T, Tanaka H, Nishiwaki K, Wakita S, Inokuchi K, Fukushima T, Yoshida C, Uoshima N, Kiguchi T, Mita M, Aoki J, Kimura S, Karimata K, Usuki K, Shimono J, Chinen Y, Kuroda J, Matsuda Y, Nakao K, Ono T, Fujimaki K, Shibayama H, Sakamoto J, Kimura S.
    • Journal Title

      Lancet Haematol

      Volume: 8 Issue: 12 Pages: e902-e911

    • DOI

      10.1016/s2352-3026(21)00333-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08861, KAKENHI-PROJECT-20K07150, KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-21K16245
  • [Journal Article] Adult T‐cell leukemia‐lymphoma acquires resistance to <scp>DNA</scp> demethylating agents through dysregulation of enzymes involved in pyrimidine metabolism2021

    • Author(s)
      Yoshida‐Sakai Nao、Watanabe Tatsuro、Yamamoto Yuta、Ureshino Hiroshi、Kamachi Kazuharu、Kurahashi Yuki、Fukuda‐Kurahashi Yuki、Kimura Shinya
    • Journal Title

      International Journal of Cancer

      Volume: 150 Issue: 7 Pages: 1184-1197

    • DOI

      10.1002/ijc.33901

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07593, KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-21K16245
  • [Journal Article] RUNX1 transactivates BCR‐ABL1 expression in Philadelphia chromosome positive acute lymphoblastic leukemia2021

    • Author(s)
      Masuda Tatsuya、Maeda Shintaro、Shimada Sae、Sakuramoto Naoya、Morita Ken、Koyama Asami、Suzuki Kensho、Mitsuda Yoshihide、Matsuo Hidemasa、...、Kamikubo Yasuhiko
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 2 Pages: 529-539

    • DOI

      10.1111/cas.15239

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16832, KAKENHI-PROJECT-20H05667, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-21K06909, KAKENHI-PROJECT-21K19353, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-20K08726
  • [Journal Article] HLA Polymorphisms Are Associated with Treatment-Free Remission Following Discontinuation of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia2021

    • Author(s)
      Ureshino H, Shindo T, Tanaka H, Saji H, Kimura S
    • Journal Title

      Molecular Cancer Therapeutics

      Volume: 20 Issue: 1 Pages: 142-149

    • DOI

      10.1158/1535-7163.mct-20-0336

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-19K17860, KAKENHI-PROJECT-19K08812
  • [Journal Article] Silylation of Deoxynucleotide Analog Yields an Orally Available Drug with Antileukemia Effects2021

    • Author(s)
      Ureshino Hiroshi、Kurahashi Yuki、Watanabe Tatsuro、Yamashita Satoshi、Kamachi Kazuharu、Yamamoto Yuta、Fukuda-Kurahashi Yuki、Yoshida-Sakai Nao、Hattori Naoko、Hayashi Yoshihiro、Kawaguchi Atsushi、Tohyama Kaoru、Okada Seiji、Harada Hironori、Ushijima Toshikazu、Kimura Shinya
    • Journal Title

      Molecular Cancer Therapeutics

      Volume: 20 Issue: 8 Pages: 1412-1421

    • DOI

      10.1158/1535-7163.mct-20-1125

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08824, KAKENHI-PROJECT-20K07593, KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-21K16245, KAKENHI-PROJECT-19H04355
  • [Journal Article] Budget impact analysis of treatment-free remission in nilotinib-treated Japanese chronic myeloid leukemia patients2020

    • Author(s)
      Yamazaki K, Inagaki N, Moldaver D, Viana R, Kimura S
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 7 Pages: 2526-2535

    • DOI

      10.1111/cas.14430

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Journal Article] Phosphorylated ERK1/2 in CD4 T cells is associated with acute GVHD in allogeneic hematopoietic stem cell transplantation2020

    • Author(s)
      Itamura H, Shindo T, Yoshida S, Ishikawa T, Kimura S
    • Journal Title

      Blood Avvances

      Volume: 4 Issue: 4 Pages: 667-671

    • DOI

      10.1182/bloodadvances.2019000343

    • NAID

      120006878504

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09908, KAKENHI-PROJECT-19K08812
  • [Journal Article] Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis by using the new oral demethylating agent OR-21002020

    • Author(s)
      Watanabe Tatsuro、Yamashita Satoshi、Ureshino Hiroshi、Kamachi Kazuharu、Kurahashi Yuki、Fukuda-Kurahashi Yuki、Yoshida Nao、Hattori Naoko、Nakamura Hideaki、Sato Akemi、Kawaguchi Atsushi、Sueoka-Aragane Naoko、Kojima Kensuke、Okada Seiji、Ushijima Toshikazu、Kimura Shinya、Sueoka Eisaburo
    • Journal Title

      Blood

      Volume: 136 Issue: 7 Pages: 871-884

    • DOI

      10.1182/blood.2019003084

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07593, KAKENHI-PROJECT-20K07700, KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-19K17860
  • [Journal Article] Treatment-free remission after first-line dasatinib discontinuation in patients with chronic myeloid leukaemia (first-line DADI trial): a single-arm, multicentre, phase 2 trial2020

    • Author(s)
      Kimura Shinya、Imagawa Jun、Murai Kazunori、Hino Masayuki、Kitawaki Toshio、Okada Masaya、Tanaka Hideo、Shindo Motohiro、Kumagai Takashi、Ikezoe Takayuki、Uoshima Nobuhiko、Sato Tsutomu、Watanabe Reiko、Kowata Shugo、Hayakawa Masaya、Hosoki Takaaki、Ikeda Kazuhiko、et al.
    • Journal Title

      The Lancet Haematology

      Volume: 7 Issue: 3 Pages: 218-225

    • DOI

      10.1016/s2352-3026(19)30235-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08365, KAKENHI-PROJECT-19K08861, KAKENHI-PROJECT-17K09908, KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-19K17860
  • [Journal Article] C/EBPβ is a critical mediator of IFNα-induced exhaustion of chronic myeloid leukemia stem cells.2019

    • Author(s)
      Yokota A, Hirai H, Sato R, Adachi H, Sato F, Hayashi Y, Sato A, Kamino N, Miura Y, Nakano M, Tenen DG, Kimura S, Tashiro K, Maekawa T
    • Journal Title

      Blood Advances

      Volume: 3 Issue: 3 Pages: 476-488

    • DOI

      10.1182/bloodadvances.2018020503

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09908, KAKENHI-PROJECT-17K11573, KAKENHI-PROJECT-18K08354, KAKENHI-PROJECT-17H04046, KAKENHI-PROJECT-16K07171
  • [Journal Article] Naked antisense double-stranded DNA oligonucleotide efficiently suppresses BCR-ABL positive leukemic cells.2019

    • Author(s)
      Hoshiko T, Kubota Y, Akisawa T, Watanabe T, Tanigawara K, Yano J, Kimura S.
    • Journal Title

      Invest New Drugs

      Volume: - Issue: 4 Pages: 1012-1019

    • DOI

      10.1007/s10637-019-00862-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09851, KAKENHI-PROJECT-17K09908
  • [Journal Article] A new highly sensitive real-time quantitative-PCR method for detection of BCR-ABL1 to monitor minimal residual disease in chronic myeloid leukemia after discontinuation of imatinib2019

    • Author(s)
      26.Kitamura H, Tabe Y, Ai T, Tsuchiya K, Yuri M, Misawa S, Horii T, Kawaguchi A, Ohsaka A, Kimura S
    • Journal Title

      PLoS One

      Volume: 14 Issue: 3 Pages: e0207170-e0207170

    • DOI

      10.1371/journal.pone.0207170

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09908
  • [Journal Article] Final 3-year Results of the Dasatinib Discontinuation Trial in Patients With Chronic Myeloid Leukemia Who Received Dasatinib as a Second-line Treatment2018

    • Author(s)
      Okada M, Imagawa J, et al.
    • Journal Title

      Clin Lymphoma Myeloma Leuk.

      Volume: 18 Issue: 5 Pages: 353-360

    • DOI

      10.1016/j.clml.2018.03.004

    • NAID

      120006463738

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07185, KAKENHI-PROJECT-17K07142, KAKENHI-PROJECT-17K09908, KAKENHI-PROJECT-17K09953, KAKENHI-PROJECT-16K09871
  • [Journal Article] Feasibility of the Imatinib Stop Study in the Japanese Clinical Setting: Delightedly Overcome CML Expert Stop TKI Trial (DOMEST Trial).2018

    • Author(s)
      Fujisawa S, Ueda Y, Usuki K, Kobayashi K, Kondo E, Doki N, Nakao T, Kanda Y, Kosugi N, Kosug H, Kumagai T, Harada H, Shikami M, Maeda Y, Sakura T, Inokuchi K, Saito A, Nawa Y, Ogasawara M, Nishida J, Kondo T, Yoshida C, Kuroda H, Tabe Y, Maeda Y, Imajo K, Kojima K, Morita S, Komukai S, Kawaguchi A, Sakamoto J, Kimura S
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 24 Issue: 4 Pages: 445-453

    • DOI

      10.1007/s10147-018-1368-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09908, KAKENHI-PROJECT-17K09928
  • [Journal Article] Allelic polymorphisms of KIRs and HLAs predict favorable responses to tyrosine kinase inhibitors in CML.2018

    • Author(s)
      Ureshino H, Shindo T, Kojma H, Kusunoki Y, Miyazaki Y, Tanaka H, Saji H, Kawaguchi A, Kimura S
    • Journal Title

      Cancer Immunology Research

      Volume: 6 Pages: 745-754

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09908
  • [Journal Article] HMGCLL1 is a predictive biomarker for deep molecular response to imatinib therapy in chronic myeloid leukemia.2018

    • Author(s)
      Park J.-H., Woo Y.-M., Youm E., Hamad N., Won H.-H., Naka K., Park E.-J., Park J.-H., Kim H.J., Kim S.-H., Kim H., Ahn J.-S., Sohn S.-K., Moon J.-H., Jung C.-W., Park S., Lipton J., Kimura S., Jong-Won Kim J.-W., Kim D.
    • Journal Title

      Leukemia

      Volume: epub ahead of print Issue: 6 Pages: 1439-1450

    • DOI

      10.1038/s41375-018-0321-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03578, KAKENHI-PROJECT-17K19599, KAKENHI-PROJECT-17K09908
  • [Journal Article] Anxiety and depression associated with tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia.2018

    • Author(s)
      Sogawa R, Kimura S, Yakabe R, Mizokami Y, Tasaki M, Sueoka-Aragane N, Narisawa Y, Kimura S
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 23 Issue: 5 Pages: 974-979

    • DOI

      10.1007/s10147-018-1275-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09908
  • [Journal Article] Detection of KRAS Mutations in plasma DNA using a fully automated rapid detection system in colorectal cancer patients2017

    • Author(s)
      Hosoya K, Matsusaka S, Kashiwada T, Suzuki K, Ureshino N, Sato A, Miki Y, Kitera K, Hirai M, Hatake K, Kimura S, Sueoka-Aragane N
    • Journal Title

      Pathol Oncol Res

      Volume: Epub ahead of print Pages: 1007-1007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Journal Article] Chronic myelogenous leukemia and NK cell immunity.2017

    • Author(s)
      Ureshino H, Shindo T, Tanaka H, Kimura S
    • Journal Title

      Rinsho Ketsueki

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461451
  • [Journal Article] Persistent Gastrointestinal Angiodysplasia in Heyde’s syndrome after aortic valve replacement.2017

    • Author(s)
      Akutagawa T, Shindo T*, Yamanouchi K, Hayakawa M, Ureshino H, Tsuruoka N, Sakata Y, Shimoda R, Noguchi R, Furukawa K, Morita S, Iwakiri R, Kimura S, Matsumoto M, Fujimoto K
    • Journal Title

      Intern Med

      Volume: 印刷中

    • NAID

      130006078531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461451
  • [Journal Article] Mutation profile of B-raf gene analyzed by fully automated system and clinical features in Japanese melanoma patients2017

    • Author(s)
      Ide M, Koba K, Sueoka-Aragane N, Sato A, Nagano Y, Inoue T, Misago N, Narisawa Y, Kimura S, Sueoka E
    • Journal Title

      Pathol Oncol Res

      Volume: 23 Pages: 181-188

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Journal Article] Elderly patients with chronic myeloid leukemia benefit from a dasatinib dose as low as 20 mg.2017

    • Author(s)
      Itamura H, Kubota Y, Shindo T, Ando T, Kojima K, Kimura S
    • Journal Title

      Clin Lymph Myeloma Leuk

      Volume: 印刷中 Issue: 6 Pages: 370-374

    • DOI

      10.1016/j.clml.2017.02.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461451, KAKENHI-PROJECT-16K09851, KAKENHI-PROJECT-17K09928
  • [Journal Article] SPARC is a Possible Predictive Marker for Albumin-bound Paclitaxel in Non-small Cell Lung Cancer2016

    • Author(s)
      Komiya K, Nakamura T, Nakashima C, Takahashi K, Umeguchi H, Watanabe N, Sato A, Takeda Y, Kimura S, Sueoka-Aragane N
    • Journal Title

      Onco Targets Ther

      Volume: 9 Pages: 6663-6668

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Journal Article] The MEK inhibitor trametinib separates murine Graft-versus-Host Disease from Graft-versus-Tumor Effects.2016

    • Author(s)
      Itamura H, Shindo T*, Tawara I, Kubota Y, Kariya R, Okada S, Komanduri KV, Kimura S
    • Journal Title

      JCI Insight

      Volume: 1 Issue: 10

    • DOI

      10.1172/jci.insight.86331

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461451
  • [Journal Article] Rituximab-induced Acute Thrombocytopenia in High Tumor Burden Follicular Lymphoma2016

    • Author(s)
      Ureshino H, Nishioka A, Kojima K, Suzuki M, Kizuka H, Sano H, Shindo T, Kubota Y, Ando T, Kimura S
    • Journal Title

      Intern. Med.

      Volume: 55 Issue: 15 Pages: 2061-2064

    • DOI

      10.2169/internalmedicine.55.6140

    • NAID

      130005254817

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461451, KAKENHI-PROJECT-16K09851
  • [Journal Article] Subdural Hematoma Associated with Dasatinib and Intrathecal Methotrexate Treatment in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia2016

    • Author(s)
      Ureshino H, Nishioka A, Kojima K, Kizuka H, Sano H, Shindo T, Kubota Y, Ando T, Kimura S
    • Journal Title

      Intern. Med.

      Volume: 55 Issue: 18 Pages: 2703-2706

    • DOI

      10.2169/internalmedicine.55.6966

    • NAID

      130005414849

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461451, KAKENHI-PROJECT-16K09851
  • [Journal Article] Effector regulatory T cells reflect the equilibrium between antitumor immunity and autoimmunity in adult T cell leukemia.2016

    • Author(s)
      Ureshino H, Shindo T*, Nishikawa H, Watanabe N, Watanabe E, Satoh N, Kitaura K, Kitamura H, Doi K, Nagase K, Kimura H, Samukawa M, Kusunoki S, Miyahara M, Shin-I T, Suzuki R, Sakaguchi S, Kimura S
    • Journal Title

      Cancer Immunol Res

      Volume: 4 Issue: 8 Pages: 644-649

    • DOI

      10.1158/2326-6066.cir-15-0303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461451
  • [Journal Article] Domino-Style Cerebral Bleeding in a Patient With Immune Thrombocytopenic Purpura2016

    • Author(s)
      北村浩晃、進藤岳郎、薬師寺祐介、吉原麻里、久保田寧、野口智之、木村晋也
    • Journal Title

      JAMA Neurology

      Volume: 73 Issue: 4 Pages: 474-475

    • DOI

      10.1001/jamaneurol.2015.4508

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461451, KAKENHI-PROJECT-16K09851, KAKENHI-PROJECT-16K10333
  • [Journal Article] Monitoring EGFR T790M with plasma DNA from lung cancer patients in a prospective observational study2016

    • Author(s)
      Sueoka-Aragane N, Katakami N, Satouchi M, Yokota S, Aoe K, Iwanaga K, Otsuka K, Morita S, Kimura S, Negoro S, For Hanshin-Saga Collaborative Cancer Study Group
    • Journal Title

      Cancer Sci

      Volume: 107 Pages: 162-167

    • NAID

      120006335662

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Journal Article] Inhibition of HIV-1 entry by the tricyclic coumarin GUT-70 through the modification of membrane fluidity.2015

    • Author(s)
      Matsuda K, Hattori S, Kariya R, Komizu Y, Kudo E, Goto H, Taura M, Ueoka R, Kimura S, Okada S.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 457(3) Issue: 3 Pages: 288-94

    • DOI

      10.1016/j.bbrc.2014.12.102

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J08328, KAKENHI-PROJECT-14J01801, KAKENHI-PROJECT-25289299, KAKENHI-PROJECT-25420843, KAKENHI-PROJECT-25461425, KAKENHI-PROJECT-26889060
  • [Journal Article] 2-Hydroxypropyl-β-cyclodextrin Acts as a Novel Anticancer Agent.2015

    • Author(s)
      Yokoo M, Kubota Y, Motoyama K, Higashi T, Taniyoshi M, Tokumaru H, Nishiyama R, Tabe Y, Mochinaga S, Sato A, Sueoka-Aragane N, Sueoka E, Arima H, Irie T, Kimura S.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 11 Pages: 1705-1713

    • DOI

      10.1371/journal.pone.0141946

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461425
  • [Journal Article] Comparative Study of the Anti-leukemic Effects of Imatinib Mesylate, Glivec™ Tablet and Its Generic Formulation, OHK95112015

    • Author(s)
      Yokoo M, Kubota Y, Tabe Y, Kimura S
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 38 Issue: 3 Pages: 411-416

    • DOI

      10.1248/bpb.b14-00652

    • NAID

      130004872269

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461425
  • [Journal Article] Usefulness of plasma HGF level for monitoring acquired resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer2015

    • Author(s)
      Umeguchi H, Sueoka-Aragane N, Kobayashi N, Nakamura H, Sato A, Takeda Y, Hayashi S, Sueoka E, Kimura S
    • Journal Title

      Oncol Rep

      Volume: 33 Issue: 1 Pages: 391-6

    • DOI

      10.3892/or.2014.3560

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Journal Article] "Coexistence of ALK- anaplastic large cell lymphoma and CD4+ T-cell large granular lymphocytic leukemia "2015

    • Author(s)
      Kazuharu Kamachi1, Noriyasu Fukushima, Toshihiko Ando, Ken-ichi Sato, Koichi Ohshima, Masako Yokoo, Takero Shindo, Yasushi Kubota, Kensuke Kojima, Shinya Kimura
    • Journal Title

      Ann Hematol

      Volume: 94 Issue: 3 Pages: 539-540

    • DOI

      10.1007/s00277-014-2176-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461454, KAKENHI-PROJECT-26461425, KAKENHI-PROJECT-26461451, KAKENHI-PROJECT-25870130
  • [Journal Article] 抗M(IgM+IgG)において抗体価測定時に反応増強剤無添加間接抗グロブリン試験で一部陰性を示した妊婦の1例2014

    • Author(s)
      山田麻里江, 山田尚友, 久保田寧, 木村晋也, 東谷孝徳, 末岡榮三朗
    • Journal Title

      日本輸血細胞治療学会誌

      Volume: 60(1) Pages: 32-37

    • NAID

      130004542708

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Journal Article] Efficacy of the dual PI3K and mTOR inhibitor NVP-BEZ in combination with nilotinib against BCR-ABL-positive leukemia cells involves the ABL kinase domain mutation.2014

    • Author(s)
      Okabe S, Tauchi T, Tanaka Y, Kitahara T, Kimura S, Maekawa T, Ohyashiki K
    • Journal Title

      Cancer Biol Ther

      Volume: 15 Issue: 2 Pages: 207-215

    • DOI

      10.4161/cbt.26725

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24659461, KAKENHI-PROJECT-24701036, KAKENHI-PUBLICLY-25112706, KAKENHI-PROJECT-25461425
  • [Journal Article] Correlation between plasma DNA and tumor status in an animal model2014

    • Author(s)
      12.Sueoka-Aragane N, Sato A, Kobayashi N, Ide M, Yokoo M, Nagano Y, Sueoka E, Okada S, Kimura S
    • Journal Title

      PLoS One

      Volume: 9 Issue: 12 Pages: e111881-e111881

    • DOI

      10.1371/journal.pone.0111881

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461425, KAKENHI-PROJECT-26430144
  • [Journal Article] 抗M(IgM+IgG)において抗体価測定時に反応増強剤無添加間接抗グロブリン試験で一部陰性を示した妊婦の1例2014

    • Author(s)
      山田麻里江、山田尚友、久保田 寧、木村晋也、東谷孝徳、末岡榮三朗
    • Journal Title

      日本輸血細胞治療学会誌

      Volume: 60 Pages: 32-37

    • NAID

      130004542708

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Journal Article] Combining the ABL1 kinase inhibitor ponatinib and the histone deacetylase inhibitor vorinostat: a potential treatment for BCR-ABL-positive leukemia.2014

    • Author(s)
      Okabe S, Tauchi T, Kimura S, Maekawa T, Kitahara T, Tanaka Y, Ohyashiki K
    • Journal Title

      Plos One

      Volume: 9(2) Issue: 2 Pages: e89080-e89080

    • DOI

      10.1371/journal.pone.0089080

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24701036, KAKENHI-PROJECT-25461425
  • [Journal Article] Therapeutic management in cardiac lymphoma2014

    • Author(s)
      Yoshihara M, Itamura H, Fukushima N, Itoh M, Furukawa K, Nagatomo D, Kamachi K, Kitamura H, Shindo T, Kubota Y, Sueoka E, Morita S, Ichinohe T, Kimura S.
    • Journal Title

      Leuk Lymphoma

      Volume: May;55(5) (Epub 2013 Sep 3) Pages: 1215-1217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Journal Article] 電子カルテと輸血管理システムの連携による輸血後鉄過剰症モニタリングプログラムの運用とその課題2014

    • Author(s)
      末岡榮三朗, 山田尚友, 山田麻里江, 久保田寧, 吉村麻里子, 板村英和, 出勝, 横尾眞子, 吉原麻里, 蒲池和晴, 北村浩晃, 進藤岳郎, 安藤寿彦, 小島研介, 東谷孝徳, 木村晋也
    • Journal Title

      日本輸血細胞治療学会誌

      Volume: 60(1) Pages: 12-17

    • NAID

      130004542705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Journal Article] 輸血後鉄過剰症の現状と問題点2013

    • Author(s)
      末岡 榮三朗, 山田 尚友, 山田 麻里江, 久保田 寧, 浦田 千紗子, 吉村 麻里子, 板村 英和, 久富 崇, 福島 伯泰, 出 勝, 横尾 眞子, 吉原 麻里, 蒲池 和晴, 北村 浩晃, 進藤 岳郎, 一戸 辰夫, 東谷 孝徳, 木村 晋也
    • Journal Title

      日本輸血細胞治療学会誌

      Volume: 59 Pages: 73-78

    • NAID

      10031165492

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Journal Article] Development of lymphoproliferative diseases by hypoxia inducible factor-1alpha is associated with prolonged lymphocyte survival2013

    • Author(s)
      Sueoka E, Sueoka-Aragane N, Sato A, Ide M, Nakamura H, Sotomaru Y, Taya C, Yonekawa H, Kitagawa T, Kubota Y, Kimura S, Nakachi K, Tanimoto K.
    • Journal Title

      PLoS One

      Volume: Apr 12;8(4)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Journal Article] 輸血後鉄過剰症の現状と問題点2013

    • Author(s)
      末岡榮三朗, 山田尚友, 山田麻里江, 久保田寧, 浦田千紗子, 吉村麻里子, 板村英和, 久富崇, 福島伯泰, 出勝, 横尾眞子, 吉原麻里,蒲 池和晴, 北村浩晃, 進藤岳郎, 一戸辰夫, 東谷孝徳, 木村晋也
    • Journal Title

      日本輸血細胞治療学会誌

      Volume: 59(1) Pages: 73-78

    • NAID

      10031165492

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Journal Article] Regulators of the proliferation of hematopoietic stem and progenitor cells during hematopoietic regeneration2013

    • Author(s)
      Kubota Y, Kimura S.
    • Journal Title

      Stem Cell Biology in Normal Life and Diseases

      Volume: May Pages: 3-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Journal Article] Regulators of the Proliferation of Hematopoietic Stem and Progenitor Cells During Hematopoietic Regeneration2013

    • Author(s)
      Kubota Y, Kimura S.
    • Journal Title

      Stem Cell Biology in Normal Life and Diseases

      Volume: 1 Pages: 3-16

    • DOI

      10.5772/55639

    • ISBN
      9789535111078
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Journal Article] Development of lymphoproliferative diseases by hypoxia inducible factor-1alpha is associated with prolonged lymphocyte survival.2013

    • Author(s)
      Sueoka E, Sueoka-Aragane N, Sato A, Ide M, Nakamura H, Sotomaru Y, Taya C, Yonekawa H, Kitagawa T, Kubota Y, Kimura S, Nakachi K, Tanimoto K
    • Journal Title

      PLoS One

      Volume: 8 Issue: 4 Pages: e57833-e57833

    • DOI

      10.1371/journal.pone.0057833

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591393, KAKENHI-PROJECT-23791083, KAKENHI-PROJECT-25461425, KAKENHI-PROJECT-25670452
  • [Journal Article] Activity of histone deacetylase inhibitors and an Aurora kinase inhibitor in BCR-ABL expressing leukemic cells.2013

    • Author(s)
      Okabe S
    • Journal Title

      Cancer Cell International

      Volume: 13(1) Issue: 1 Pages: 32-40

    • DOI

      10.1186/1475-2867-13-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24659461, KAKENHI-PROJECT-24701036, KAKENHI-PUBLICLY-25112706, KAKENHI-PROJECT-25461425, KAKENHI-PUBLICLY-23112507
  • [Journal Article] Therapeutic management in cardiac lymphoma.2013

    • Author(s)
      Yoshihara M, Itamura H, Fukushima N, Itoh M, Furukawa K, Nagatomo D, Kamachi K, Kitamura H, Shindo T, Kubota Y, Sueoka E, Morita S, Ichinohe T, Kimura S.
    • Journal Title

      Leuk Lymphoma.

      Volume: 55 Pages: 1215-1217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Journal Article] Neuroprotective efficacy of a new brain-penetrating C-Abl inhibitor in a murine Parkinson's disease model.2013

    • Author(s)
      Imam SZ, Trickler W, Kimura S, Binienda ZK, Paule MG, Slikker W Jr, Li S, Clark RA, Ali SF.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 5 Pages: e65129-e65129

    • DOI

      10.1371/journal.pone.0065129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461425
  • [Journal Article] Zoledronic acid significantly enhances radiation induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling.2013

    • Author(s)
      8. Koto K, Murata H, Kimura S, Sawai Y, Horie N, Matsui T, Ryu K, Ashihara E, Maekawa T, Kubo T, Fushiki S.
    • Journal Title

      Int J Oncol

      Volume: 42 Issue: 2 Pages: 525-534

    • DOI

      10.3892/ijo.2012.1735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23592196, KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24659461, KAKENHI-PUBLICLY-25112706, KAKENHI-PUBLICLY-23112507
  • [Journal Article] Co-existence of MET FISH positive with EGFR mutations causes poor prognosis in lung adenocarcinoma patients2012

    • Author(s)
      Tanaka A, Sueoka-Aragane N, Nakamura T, Takeda Y, Mitsuoka M, Yamasaki F, Hayashi S, Sueoka E, Kimura S.
    • Journal Title

      Lung Cancer

      Volume: 75 Pages: 89-94

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Antitumor effect of sunitinib against skeletal metastatic renal cell carcinoma through inhibition of osteoclast function2012

    • Author(s)
      Maita S, Yuasa T, Tsuchiya N, Mitobe Y, Horikawa S, Hatake K, Fukui I, Kimura S, Maekawa T, Habuchi T.
    • Journal Title

      Int J Cancer

      Volume: 130 Pages: 677-684

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Rakicidin A effectively induces apoptosis in hypoxia adapted Bcr-Abl positive leukemic cells2011

    • Author(s)
      Takeuchi, M., Ashihara, E., Yamazaki, Y., Kimura, S., Nakagawa, Y., Tanaka, R., Yao, H., Nagao, R., Hayashi, Y., Hirai, H.
    • Journal Title

      Cancer Sci.

      Volume: 102(3) Pages: 591-596

    • NAID

      10029291246

    • Data Source
      KAKENHI-PROJECT-21390293
  • [Journal Article] Fully Integrated, Automated and Rapid Detection System for KRAS Mutations2011

    • Author(s)
      Ureshino N, Sueoka-Aragane N, Nakamura T, Sato A, Komiya K, Iwanaga K, Mitsuoka M, Takeda Y, Hayashi S, Sueoka E, Kimura S.
    • Journal Title

      Oncol Rep

      Volume: 26 Pages: 609-613

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma2011

    • Author(s)
      Jin L, Tabe Y, Kimura S, Zhou Y, Kuroda J, Asou H, Inaba T, Konopleva M, Andreeff M, Miida T.
    • Journal Title

      Brit J Cance

      Volume: 104 Pages: 91-100

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Targeting ATF-3 by Galectin-9 induces apoptosis and overcomes various types of treatment resistance in chronic myelogenous leukemia2011

    • Author(s)
      Kuroda J, Kobayashi T, Nagoshi H, Yamamoto M, Sasaki N, Taki T, Kimura S, Yamauchi A, Hirashima M, Taniwaki M.
    • Journal Title

      Mol Cancer Res

      Volume: 8 Pages: 994-1001

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Identification of a small molecule inhibitor of DNA topoisomerase II by proteomic profiling2011

    • Author(s)
      Kawatani M, Takayama H, Muroi M, Kimura S, Maekawa T. Osada H.
    • Journal Title

      Chem Biol

      Volume: 18 Pages: 743-751

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] NK314 potentiates anti-tumor activity with adult T-cell leukemia-lymphoma cells by inhibition of dual targets on topoisomerase IIa and DNA-dependent protein kinase2011

    • Author(s)
      Hisatomi T, Sueoka-Aragane N, Sato A, Tomimasu R, Ide M, Kunimasa A, Okamoto K, Kimura S, Sueoka E.
    • Journal Title

      Blood

      Volume: 117 Pages: 3575-3584

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] A Fully Integrated and Automated Detection System for Single Nucleotide Polymorphisms of UGT1A1 and CYP2C192011

    • Author(s)
      Ureshino N, Aragane N, Nakamura T, Ide M, Mochinaga S, Fukushima N, Hayashi S, Sueoka E, Kimura S.
    • Journal Title

      Oncol Res

      Volume: 19 Pages: 111-114

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Rakicidin A effectively induces apoptosis in hypoxia adapted Bcr-Abl positive leukemic cells2011

    • Author(s)
      Takeuchi M, Ashihara E, Yamazaki Y, Kimura S, Nakagawa Y, Tanaka R, Yao H, Nagao R, Hayashi Y, Hirai H, Maekawa T.
    • Journal Title

      Cencer Sci

      Volume: 102 Pages: 591-596

    • NAID

      10029291246

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Combined effects of novel heat shock protein 90 inhibitor NVP-AUY922 and nilotinib in a random mutagenesis screen2011

    • Author(s)
      Tauchi T, Okabe S, Kimura S, Maekawa T, Ohyashiki K.
    • Journal Title

      Oncogene

      Volume: 30 Pages: 2789-2797

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Clinical presentation and outcome in patients of over 75 years old with malignant lymphoma2011

    • Author(s)
      Fukushima N, Itamura H, Urata C, Tanaka M, Hisatomi T, Kunota Y, Sueoka E, Kimura S.
    • Journal Title

      Int J Clin Med

      Volume: 2 Pages: 246-253

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Growth inhibition of imatinib-resistant CML cells with the T315 mutation and hypoxia-adaptation by AV65 。Va novel Wnt/υ-catenin signaling inhibitor2011

    • Author(s)
      Nagao, R., Ashihara, E., Kimura, S., Strovel, J. W., Yao, H., Takeuchi, M., Tanaka, R., Hayashi, Y., Hirai, H., Padia, J., Strand, K.
    • Journal Title

      Cancer Letter

      Volume: 312(1) Issue: 1 Pages: 91-100

    • DOI

      10.1016/j.canlet.2011.08.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390293, KAKENHI-PROJECT-21590443, KAKENHI-PROJECT-21591246, KAKENHI-PUBLICLY-23112507, KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23592678
  • [Journal Article] Lenalidomide in combination with dexamethasone induced rhabdomyolysis in a multiple myeloma patient treated with pravastatin2011

    • Author(s)
      Urata C, Yoshimura M, Itamura H, Hisatomi T, Kubota Y, Fukushima N, Sueoka E, Kimura S.
    • Journal Title

      Int J Hematol

      Volume: 94 Pages: 216-217

    • NAID

      10029537258

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Rapid automated detection of ABL kinase domain mutations in imatinib-resistant patients2011

    • Author(s)
      Tanaka, R., Kimura, S., Ashihara, E., Yoshimura, M., Takahashi, N., Wakita, H., Itoh, K., Nishiwaki, K., Suzuki, K., Nagao, R., Yao, H., Hayashi, Y., Satake, S., Hirai, H., Sawada, K-I., Ottmann, O. G., Melo, J. V.
    • Journal Title

      Cancer Letter

      Volume: 312(2) Issue: 2 Pages: 228-34

    • DOI

      10.1016/j.canlet.2011.08.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390293, KAKENHI-PROJECT-21591246, KAKENHI-PUBLICLY-23112507, KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-23592678
  • [Journal Article] Growth inhibition of imatinib-resistant CML cells with the T315I mutation and hypoxia adaptation by AV65, a novel Wnt/β-catenin signaling inhibitor2011

    • Author(s)
      Nagao R, Ashihara E, Kimura S, Strovel JW, Yao H, Takeuchi M, Tanaka R, Hayashi Y, Hirai H, Padia J, Strand K, Maekawa T.
    • Journal Title

      Cancer Lett

      Volume: 312 Pages: 91-100

    • NAID

      120003437105

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Single-step, label-free quantification of antibody in human serum for clinical applications based on localized surface plasmon resonance2011

    • Author(s)
      Yamamichi J, Ojima T, Yurugi K, Iida M, Imamura T, Ashihara E, Kimura S, Maekawa T.
    • Journal Title

      Nanomedicine

      Volume: 7 Pages: 889-895

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Rapid automated detection of ABL kinase domain mutations in imatinib-resistant patients2011

    • Author(s)
      Tanaka R, Kimura S, Ashihara E, Yoshimura M, Takahashi N, Wakita H, Itoh K, Nishiwaki K, Suzuki K, Nagao R, Yao H, Hayashi Y, Satake S, Hirai H, Sawada K, Ottmann OG, Melo JV, Maekawa T.
    • Journal Title

      Cancer Lett

      Volume: 312 Pages: 228-234

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Galectin-9 ameliorates acute GVH disease through the induction of T-cell apoptosis2011

    • Author(s)
      Sakai K, Kawata E, Ashihara E, Nakagawa Y, Yamauchi A, Yao H, Nagao R, Tanaka R, Yokota A, Takeuchi M, Hirai H, Kimura S, Hirashima M, Yoshimura N, Maekawa T.
    • Journal Title

      Eur J Immunol

      Volume: 41 Pages: 67-75

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] A novel Wnt/β-catenin signal inhibitor successfully suppresses progression of multiple myeloma in a mouse model2011

    • Author(s)
      Yao, H., Ashihara, E., Strovel, J. W., Nakagawa, Y., Kuroda, J., Nagao, R., Tanaka, R., Yokota, A., Takeuchi, M., Sakai, K., Shimazaki, C., Taniwaki, M., Strand, K., Padia, J., Hirai, H., Kimura, S.
    • Journal Title

      Blood Cancer J

      Volume: 1

    • Data Source
      KAKENHI-PROJECT-21390293
  • [Journal Article] Combined effects of novel heat shock protein 90 inhibitor NVP-AUY922 and nilotinib in a random mutagenesis screen2011

    • Author(s)
      Tauchi, T., Okabe, S., Ashihara, E., Kimura, S., Maekawa, T.
    • Journal Title

      Oncogene

      Volume: 30(24) Pages: 2789-2797

    • Data Source
      KAKENHI-PROJECT-21390293
  • [Journal Article] A non-invasive system for monitoring resistance to EGFR tyrosine kinase inhibitors with plasma DNA2011

    • Author(s)
      Nakamura T, Sueoka-Aragane N, Iwanaga K, Sato A, Komiya K, Abe T, Ureshino N, Hayashi S, Hosomi T, Hirai M, Sueoka E, Kimura S.
    • Journal Title

      J Thorac Oncol

      Volume: 6 Pages: 1639-1648

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Primary hepatic extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type is associated with chronic inflammatory process2010

    • Author(s)
      Tanaka M, Fukushima N, Yamasaki F, Ohshima K, Sueoka E, Kimura S.
    • Journal Title

      Open J Hemato

      Volume: 1 Pages: 1-5

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Uncommon case of chronic myeloid leukemia with multiple myeloma2010

    • Author(s)
      Ide M, Kuwahara N, Matsuishi E, Kimura S, Gondo H.
    • Journal Title

      Int J Hemmatol

      Volume: 91 Pages: 699-704

    • NAID

      10026402271

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Activity of the multi-targeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL positive leukemic cells2010

    • Author(s)
      Tanaka R, Squires MS, Kimura S, Yokota A, Nagao R, Yamauchi T, Takeuchi M, Yao H, Reule M, Smyth T, Lyon JF, Thompson NT, Ashihara E, Ottmann OG, Maekawa T.
    • Journal Title

      Blood

      Volume: 116 Pages: 2089-2095

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Combined effects of bisphosphonate and radiation on osteosarcoma cells.2010

    • Author(s)
      Ryu K, Murata H, Koto K, Horie N, Matsui T, Nishigaki Y, Sakabe T, Takeshita H, Itoi M, Kimura S, Ashihara E, Maekawa T, Fushiki S, Kubo T.
    • Journal Title

      Anticancer Res 30

      Pages: 2713-2720

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591764
  • [Journal Article] Activity of the multi-targeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL positive leukemic cells2010

    • Author(s)
      Tanaka, R., Squires, M. S., Kimura, S., Yokota, A., Mallet, K., Smyth, T., Thompson, N. T., Nagao, R., Yamauchi, T., Ashihara, E., Ottmann, O. G., Lyons, J. F.
    • Journal Title

      Blood

      Volume: 116(12) Pages: 2089-2095

    • Data Source
      KAKENHI-PROJECT-21390293
  • [Journal Article] Osteoclasts are involved in the maintenance of dormant leukemic cells2010

    • Author(s)
      Yokota, A., Kimura, S., Tanaka, R., Takeuchi, M., Yao, H., Sakai, K., Nagao, R., Kuroda, J., Kamitsuji, Y., Kawata, E.
    • Journal Title

      Leuk Res.

      Volume: 34 Pages: 793-799

    • Data Source
      KAKENHI-PROJECT-21390293
  • [Journal Article] Combined effects of bisphosphonate and radiation on osteosarcoma cells2010

    • Author(s)
      Ryu K, Murata H, Koto K, Horie N, Matsui T, Nishigaki Y, Sakabe T, Takeshita H, Itoi M, Kimura S, Ashihara E, Maekawa T, Fushiki S, Kubo T.
    • Journal Title

      Anticancer Res

      Volume: 30 Pages: 2713-2720

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro.2010

    • Author(s)
      Kawata E, Ashihara E, Nakagawa Y, Kiuchi T, Ogura M, Yao H, Sakai K, Tanaka R, Nagao R, Yokota A, Takeuchi M, Kimura S, Hirai H, Maekawa T.
    • Journal Title

      Cancer Lett 294

      Pages: 245-253

    • NAID

      120002462958

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Journal Article] Loxoprofen Sodium, a Non-Selective NSAID, Reduces Atherosclerosis in Mice by Reducing Inflammation2010

    • Author(s)
      Hamaguchi M, Seno T, Yamamoto A, Kohno M, Kadoya M, Ishino H, Ashihara E, Kimura S, Tsubakimoto Y, Takata H, Yoshikawa T, Maekawa T, Kawahito Y.
    • Journal Title

      JClin Biochem Nutr

      Volume: 47 Pages: 138-147

    • NAID

      130004879204

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Zoledronic acid inhibits proliferation of human fibrosarcoma cells with induction of apoptosis, and shows combined effects with other anticancer agents2010

    • Author(s)
      Koto K, Murata H, Kimura S, Horie N, Matsui T, Nishigaki Y, Ryu K, Sakabe T, Ashihara E, Maekawa T, Fushiki S, Kubo T.
    • Journal Title

      Oncol Rep

      Volume: 24 Pages: 233-239

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Zoledronic acid inhibits proliferation of human fibrosarcoma cells with induction of apoptosis, and shows combined effects with other anticancer agents.2010

    • Author(s)
      Koto K, Murata H, Kimura S, Horie N, Matsui T, Nishigaki Y, Ryu K, Sakabe T, Itoi M, Ashihara E, Maekawa T, Fushiki S, Kubo T.
    • Journal Title

      Oncol Rep 24

      Pages: 233-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591764
  • [Journal Article] Noninvasive tracking of donor cell homing by near-infrared fluorescence imaging shortly after bone marrow transplantation2010

    • Author(s)
      Ushiki T, Kizaki-Kondoh S, Ashihara E, TanakaS, Nasuko M, Hirai H, Kimura S, Aizawa Y, Maekawa T, Hiraoka M.
    • Journal Title

      PLoS One

      Volume: 5

    • NAID

      120002511315

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Osteoclasts are involved in the maintenance of dormant leukemic cells2010

    • Author(s)
      Yokota A, Kimura S, Tanaka R, Takeuchi M, Yao H, Sakai K, Nagao R, Kuroda J, Kamitsuji Y, Kawata E, Ashihara E, Maekawa T.
    • Journal Title

      Leuk Res

      Volume: 34 Pages: 793-799

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] A combination of a DNA-chimera 1 siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro2010

    • Author(s)
      Kawata E, Ahihara E, Nakagawa Y, Kiuchi T, Ogura M, Yao H, Sakai K, Tanaka R, Nagao R, Yokota A, Takeuchi M, Kimura S, Hirai H, Maekawa T.
    • Journal Title

      Cancer Lett

      Volume: 294 Pages: 245-253

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Isolation of mesenchymal stem cells from bone marrow in the closed system using a new device made by non-woven fabrics2010

    • Author(s)
      Ito K, Aoyama T, Fukiage K, Otsuka S, Furu M, Jin Y, Nasu A, Ueda M, Kasai Y, Ashihara E, Kimura S, Maekawa T, Kobayashi A, Yoshida S, Otsuka T, Nakamura T, Toguchida J.
    • Journal Title

      Tissue Eng Part C Methods

      Volume: 16 Pages: 81-91

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in hypoxic environment2010

    • Author(s)
      Takeuchi M, Kimura S, Kuroda J, Ashihara E, Kawatani M, Osada H, Umezawa K, Yasui E, Imoto M, Tsuruo T, Yokota A, Tanaka R, Nagao R, Nakahara T, Fujiyama Y, Maekawa T.
    • Journal Title

      Cell Death Diff

      Volume: 17 Pages: 1211-1220

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Phase I study of INNO-406, a dual Abl/ Lyn kinase inhibitor, in Philadelphia chromosome-positive leukemias post-imatinib resistance or intolerance2010

    • Author(s)
      Kantarjian H, le Coutre P, Cortes J, Pinilla-lbarz J, Nagler A, Hochhaus A, Kimura S, Ottmann 0.
    • Journal Title

      Cancer

      Volume: 16 Pages: 2665-2672

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Blockade of the ERK or PI3K-Akt signaling pathway enhances the cytotoxicity of histone deacetylase inhibitors in tumor cells resistant to gefitinib or imatinib2010

    • Author(s)
      Ozaki K, Kosugi M, Baba N, Fujio K, Sakamoto T, Kimura S, Tanimura S, Kohno M.
    • Journal Title

      Biochem Biophys Res COMMUll

      Volume: 391 Pages: 1610-1615

    • NAID

      120006983583

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like 5characteristics in a hypoxic environment2010

    • Author(s)
      Takeuchi, M., Kimura, S., Kuroda, J., Ashihara, E., Kawatani, M., Osada, H., Umezawa, K., Yasui, E., Imoto, M., Tsuruo, T., Yokota, A., Tanaka, T., Nagao, R., Nakahata, T., Fujiyama, Y.
    • Journal Title

      Cell Death Diff

      Volume: 7 Pages: 1211-1220

    • Data Source
      KAKENHI-PROJECT-21390293
  • [Journal Article] Gangrenous cheilitis associated with all-trans retinoic acid therapy for acute promyelocyt c leukemia2010

    • Author(s)
      Tanaka M, Fukushima N, Urata C, Yokoo M, Ide M, Hisatomi T, Tomimasu R, Sueoka E, Kimura S.
    • Journal Title

      Int J Hematol

      Volume: 91 Pages: 132-135

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] β-catenin siRNA successfully suppressed progression of multiple myeloma in a mouse model.2009

    • Author(s)
      Ashihara E, Kawata E, Nakagawa Y, Shimazaki C, Kuroda J, Taniguchi T, Uchiyama H, Tanaka R, Yokota A, Takeuchi M, Kamitsuji Y, Inaba T, Taniwaki M, Kimura S, Maekawa T
    • Journal Title

      Clin Cancer Res 15

      Pages: 2731-2738

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Journal Article] Clinically relevant dose of zoledronic acid inhibits spontaneous lung metastasis in a murine osteosarcoma model2009

    • Author(s)
      Koto K, Horie N, Kimura S, Murata H, Sakabe T, Matsui T, Watanabe M, Adachi S, Maekawa T, Fushiki S, Kubo T.
    • Journal Title

      Cancer Lett

      Volume: 274 Pages: 271-278

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article]2009

    • Author(s)
      木村晋也
    • Journal Title

      造血器腫瘍アトラス(日本医事新報社)

      Pages: 476-480

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Wada. Monitoring with a non-invasive bioluminescent in vivo imaging system of successful treatment of disseminated pleural tumors by intra-pleural docetaxel administration2009

    • Author(s)
      Matsumoto S, Tanaka F, Sato K, Kimura S, Maekawa T, Hasegawa S
    • Journal Title

      Lung Cancer

      Volume: 66 Pages: 75-79

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Dual BCR-ABL/LYN tyrosine kinase inhibitor2009

    • Author(s)
      Takeuchi M, Kimura S, Ashihara E, Maekawa T
    • Journal Title

      Drug Fut

      Volume: 34(4) Pages: 261-269

    • Data Source
      KAKENHI-PROJECT-21390293
  • [Journal Article] Intravesical administration of・・T cells successfully prevents the growth of bladder cancer in the murine model2009

    • Author(s)
      Yuasa T, Sato K, Ashihara E, Takeuchi M, Maita S, Tsuchiya N, Habuchi T, Maekawa T, Kimura S.
    • Journal Title

      Cancer Immunol Immun

      Volume: 58 Pages: 493-502

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] β-catenin siRNA successfully suppressed progression of multiple myeloma in a mouse model2009

    • Author(s)
      Ashihara E, Kawata E, Nakagawa Y, Shimazaski C, Kuroda J, Tanaka R, Yokota A, Murotani Y, Takeuchi M, Kamitsuji Y, Inaba T, Taniwaki T, Kimura S, Maekawa T.
    • Journal Title

      Clin Cancer Res

      Volume: 15 Pages: 2731-2738

    • Data Source
      KAKENHI-PROJECT-21591201
  • [Journal Article] Dua I BCR-ABL/LYN tyrosine kinase inhibitor2009

    • Author(s)
      Takeuchi, M., Kimura, S., Ashihara, E., Maekawa, T
    • Journal Title

      Drug of the Future INNO-406(in press)

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] Clinically relevant dose of zoledronic acid inhibits spontaneous lung metastasis in a murine osteosarcoma model.2009

    • Author(s)
      Koto, K., Horie, N., Kimura, S., Murata, H., et. al
    • Journal Title

      Cancer Lett 274

      Pages: 271-278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591764
  • [Journal Article] Clinically relevant dose of zoledronic acid inhibits spontaneous lung metastasis in a murine osteosarcoma model.2009

    • Author(s)
      Koto K, Horie N, Kimura S, Murata H, Sakabe T, Matsui T, Watanabe M, Adachi S, Maekawa T, Fushiki S, Kubo T.
    • Journal Title

      Cancer Lett 274

      Pages: 271-278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591764
  • [Journal Article] Comaprison of imatinib, dasatinib, nilotinib, and INNO-406 in imatinib-resistant cell lines2008

    • Author(s)
      Deguchi, Y., Kimura, S., Ashihara, E.,Niwa, T., Hodohara, K., Fujiyama, Y., Maekawa, T.
    • Journal Title

      Leuk Res 32(6)

      Pages: 980-983

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] ビスホスホネートでex vivo増幅したγδ.T細胞による免疫細胞療法.2008

    • Author(s)
      木村晋也
    • Journal Title

      Clinical Calcium (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] Overcoming imatinib resistance using Src inhibitor CGP760302008

    • Author(s)
      Morinaga, K., Yamauchi, T., Kimura, T. Maekawa, T., Ueda, T
    • Journal Title

      Abl inhibitor nilotinib, and Abl/Lyn inhibitor INNO-406 in newly established K562 variants with BCR-ABL gene amplification. Int J Cancer 122(11)

      Pages: 2621-2627

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] 新規ABLチロシンキナーゼ阻害剤-生き残るのはどれか-2008

    • Author(s)
      木村晋也
    • Journal Title

      ファルマシア 44

      Pages: 213-217

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] JAK2V617F-positive essential thrombocythemia and multiple myeloma with IGH/CCND1 gene translocation co-exits, but originate from separate clones.2008

    • Author(s)
      Kuroda J, Matsumoto Y, Tanaka R, Kurita K, Kobayashi T, Shimizu D, Kimura S, Shimazaki C, Horiike S, Shimazaki C, Taniwaki M.
    • Journal Title

      Acta Haematol 120

      Pages: 177-181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Journal Article] ABT-737 is a useful component of combinatory chemotherapies for chronic myelogenous leukaemias with diverse drug resistance mechanisms2008

    • Author(s)
      Kuroda, J., Kimura, S., Kamitsuji, Y., Yokota, A., Ashihara, E., Kawata, E., Takeuchi, M., Tanaka, R., Tanaka, H., Matsumoto, Y., Andreeff, M., Taniwaki, M., Maekawa, T.
    • Journal Title

      Brit J Haematol 140(2)

      Pages: 181-190

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer.2008

    • Author(s)
      Kawata E, Ashihara E, Kimura S, Takenaka K, Sato K, Tanaka R, Yokota A, Kamitsuji Y, Takeuchi M, Kuroda J, Tanaka F, Yoshikawa T, Maekawa T.
    • Journal Title

      Mol Cancer Ther 7

      Pages: 2904-2912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Journal Article] Anti-myeloma effect of homoharringtonine with concomitant targeting of the myeloma-promoting molecules, Mcl-1, XIAP, and beta-catenin.2008

    • Author(s)
      Kuroda J, Kamitsuji Y, Kimura S, Ashihara E, Kawata E, Nakagawa Y, Takeuichi M, Murotani Y, Yokota A, Tanaka R, Andreeff M, Taniwaki M, Maekawa T.
    • Journal Title

      Int J Hematol 87

      Pages: 507-515

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Journal Article] Detection of the V617F mutation in JAK2 using a novel, fully automated2008

    • Author(s)
      Tanaka, R., Kuroda, J., Stevenson, I. Ashihara, E., Ishikawa, T., Taki, T. Kobayashi, Y., Kamitsuji, Y., Kawata, E., Takeuchi, M., Murotani, Y., Yokota, A., Hirai, M., Majima, S., Taniwaki, M. Maekawa, T., Kimura, S
    • Journal Title

      SNP super-rapid detector. Leuk Res 32(9)

      Pages: 1462-1467

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels2008

    • Author(s)
      木村晋也
    • Journal Title

      分子細胞治療 (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] Anti-myeloma effect of Homoharringtonine with concomitant targeting of multiple myeloma-promoting molecules Mcl-1, XIAP and b-catenin2008

    • Author(s)
      Kuroda, J., Kamitsuji, Y., Kimura, S., Ashihara, E., Nakagawa, Y., Kawata, E. Takeuchi, M., Murotani, Y., Yokota, A., Tanaka, R., Andreeff, M., Taniwaki, M., Maekawa, T.
    • Journal Title

      Int J Hematol 87(5)

      Pages: 507-515

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] Modes of cell death execution and autophagy by INNO-406, a Bcr-Abl kinase inhibitor, in Bcr-Abl-positive leukemias2008

    • Author(s)
      Kamitsuji, Y., Kuroda, J., Kimura, S., Toyokuni, S., Watanabe, K., Ashihara, E., Tanaka, H., Watanabe, M., Matsubara, H., Mizushima, Y., Hiraumi, Y., Kawata E., Yoshikawa, T., Maekawa, T., Nakahata, T., Adachi, S
    • Journal Title

      Cell Death Diff 15(11)

      Pages: 1712-1722

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor suppresses the growth of Ph^+ leukemia cells in the central nervous system and cyclosporine A augments its in vivo activity2007

    • Author(s)
      Yokota, A., Kimura, S., Masuda, S., Ashihara, E., Kuroda, J., Sato, K., Kamitsuji, Y., Kawata, E., Deguchi, Y., Urasaki, Y., Terui, Y., Ruthardt, M., Ueda, T., Hatake, K., Inui, K., and Maekawa, T.
    • Journal Title

      Blood 109(1)

      Pages: 306-314

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] Ph陽性白血病に対する新規チロシンキナーゼ阻害剤の開発状況2007

    • Author(s)
      木村晋也
    • Journal Title

      血液・腫瘍科 54

      Pages: 710-718

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] Dual molecular targeting by INNO-406, a second generation Bcr-Abl inhibitor, and ABT737, an inhibitor of anti-apoptotic Bcl-2 proteins against Bcr-Abl-positive leukemia2007

    • Author(s)
      Kuroda, J., Kimura, S., Strasser, A., Andreeff, M., O' Reilly, L.A., Ashihara, E., Kamitsuji, Y., Yokota, A., Kawata, E., Deguchi, Y., Takeuchi, M., Tabe, Y., Taniwaki, M., Maekawa, T.
    • Journal Title

      Cell Death Diff 14(9)

      Pages: 1667-77

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] 新しい分子標的薬2007

    • Author(s)
      木村晋也
    • Journal Title

      日本臨床 65

      Pages: 46-51

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] The Bcr-Abl tyrosine kinase inhibitor imatinib and promising new agents against Philadelphia chromosome positive leukemias2007

    • Author(s)
      Maekawa, T., Ashihara, E., Kimura, S.
    • Journal Title

      Review. Int J Clin Oncol 12(5)

      Pages: 327-340

    • NAID

      10019800087

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] INNO-406, a novel BCR-ABL/LYN dual tyrosine kinase inhibitor, suppress the growth of Ph^+ leukemia cells in the central nervous system and cyclosporine A augments its in vivo activity2007

    • Author(s)
      Yokota, A., Kimura, S., Masuda, M., et. al.
    • Journal Title

      Blood 109

      Pages: 306-314

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] Combined effects of a third-generation bisphosphonate, zoledronic acid with other anti-cancer agents against osteosarcoma2007

    • Author(s)
      Hale, N., Murata, H., Kimura, S., et. al.
    • Journal Title

      Brit J Cancer 96

      Pages: 255-261

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] 新たなABLチロシンキナーゼ阻害剤2007

    • Author(s)
      木村晋也
    • Journal Title

      医学のあゆみ 224

      Pages: 109-114

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] Ph陽性白血病治療におけるBCR-ABL変異検出の臨床的意義.2007

    • Author(s)
      木村晋也
    • Journal Title

      Front Wave in Hematology 21

      Pages: 8-9

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] CMLに対する分子標的2007

    • Author(s)
      木村 晋也
    • Journal Title

      臨床血液 48

      Pages: 46-55

    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] CMLに対する分子標的2007

    • Author(s)
      木村晋也
    • Journal Title

      臨床血液 48

      Pages: 46-55

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] γδ T cells kill myeloma cell by sensing mevalonate metabolites and ICAM-1 molecules on cell surface2007

    • Author(s)
      Uchida, R., Ashihara, E., Sato, K., Kimura, S., et. al.
    • Journal Title

      Biochem Biophys Res Commun 354

      Pages: 613-618

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] 新たなABLチロシンキナーゼ阻害剤2007

    • Author(s)
      木村晋也
    • Journal Title

      医学のあゆみ 220

      Pages: 783-788

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] 白血病のin vivoイメージング2006

    • Author(s)
      木村晋也
    • Journal Title

      がん分子標的治療 4

      Pages: 67-71

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] Second Generation Abl Kinase Inhibitors and Novel Compounds to Eliminate the Bcr-Abl/T3151 Clone.2006

    • Author(s)
      Kimura S
    • Journal Title

      Recent Patent Review on Anti-Cancer Drug Discovery 1

      Pages: 347-355

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] Development of NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor2006

    • Author(s)
      Kimura S, et al.
    • Journal Title

      Cancer Chemo Pharmacol 58・Suppl 7

      Pages: 55-61

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] New Tyrosine Kinase Inhibitors in the Treatment of Chronic Myeloid Leukemia.2006

    • Author(s)
      Kimura S
    • Journal Title

      Curr Pharm Bio 7

      Pages: 371-379

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] 新規dual Bcr-Abl/Lyn kinase inhibitor, NS-187.2006

    • Author(s)
      木村晋也
    • Journal Title

      血液・腫瘍科 52

      Pages: 555-562

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] Development of NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor2006

    • Author(s)
      Kimura, S., Niwa, T., Hirabayashi, K., Maekawa, T.
    • Journal Title

      Cancer Chemo Pharmacol 58 Suppl 7

      Pages: 55-61

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] In vivo antiproliferative effect of NS-187, Bcr-Abl/Lyn tyrosine kinase inhibitor, on leukemic cells harbouring Abl kinase domain mutations2006

    • Author(s)
      Naito, H., Kimura, S., Nakaya, Y., et. al.
    • Journal Title

      Leuk Res 30

      Pages: 1443-1446

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] In vivo inhibitory effect of NS-187, a dual Bcr-Abl/Lyn tyrosine kinase inhibitor, on the proliferation of leukemic cells harbouring Abl kinase domain mutations2006

    • Author(s)
      Naito, H., Kimura, S., Nakaya, Y., Naruoka, H., Ito, S., Wakayama, T., Maekawa, T. and Hirabayashi, K.
    • Journal Title

      Leuk Res 30(11)

      Pages: 1443-1446

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] In vivo inhibitory effect of NS-187, a dual Bcr-Abl/Lyn tyrosine kinase inhibitor, on the proliferation of leukemic cells harbour ing Abl kinase domain mutations2006

    • Author(s)
      Naito, H., Kimura, S., Nakaya, Y., Naruoka, H., Kimura, S., Ito, S., Wakayama, T., Maekawa, T. and Hirabayashi, K.
    • Journal Title

      Leuk Res 30(11)

      Pages: 1443-1446

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] New tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia(review)2006

    • Author(s)
      Kimura, S., Ashihara, E., Maekawa, T.
    • Journal Title

      Curr Pharma. Biotech 7(5)

      Pages: 371-379

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] Development of NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor. Cancer Chemoth Pharm2006

    • Author(s)
      Kimura S
    • Journal Title

      Cancer Chemoth Pharm 58

      Pages: 55-61

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] Pro-apoptotic BH3-only proteins Bim and Bad mediate imatinib-induced killing of Bcr/Abl^+ leukemic cells and resistance due to their loss is overcome by a BH3 mimetic2006

    • Author(s)
      Kuroda, J., Puthalakath, H., Cragg, MS., Kelly, PN., Bouillet, P., Huang, DCS., Kimura, S., et. al.
    • Journal Title

      Proc Natl Aced Sci USA 103

      Pages: 14907-14912

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] A third generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo2006

    • Author(s)
      Sato, K., Yuasa, T., Nogawa, M., Kimura, S., et. al.
    • Journal Title

      Brit J Cancer 95

      Pages: 1354-1361

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] 慢性骨髄性白血病に対する分子標的治療.2006

    • Author(s)
      木村晋也
    • Journal Title

      京都府立医大雑誌. 115

      Pages: 749-760

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] New tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia2006

    • Author(s)
      Kimura S, et al.
    • Journal Title

      Curr Pharma. Biotech 7・5

      Pages: 371-379

    • Data Source
      KAKENHI-PROJECT-18390283
  • [Journal Article] 新規dual Bcr-Ab1/Lyn kinase inhibitor, NS-187.2006

    • Author(s)
      木村晋也
    • Journal Title

      血液・腫瘍科 52

      Pages: 555-562

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Journal Article] Rapid Quantitation of IgG Antibodies Specific for Blood Group Antigens A and B by Surface Plasmon Resonance.2005

    • Author(s)
      Kimura S
    • Journal Title

      Transfusion 45

      Pages: 56-62

    • Data Source
      KAKENHI-PROJECT-16659438
  • [Journal Article] Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.2005

    • Author(s)
      Nogawa M, Yuasa T, Kimura S, Kuroda J, Sato K, Segawa H, Maekawa T.
    • Journal Title

      Cancer Lett 217

      Pages: 243-253

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591005
  • [Journal Article] The anti-leukemic efficacy of the third generation bisphosphonate ONO5920/YM529.2005

    • Author(s)
      Segawa H, Kimura S, Kuroda J, Sato K, Nogawa M, Yuasa T, Yokota A, Hodohara K, Fujiyama Y, Maekawa T.
    • Journal Title

      Leuk Res 29

      Pages: 451-457

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591005
  • [Journal Article] Inhibition of leukemic cell growth by a novel anti-cancer drug (GUT-70) from Calophyllim brasiliense that acts by induction of apoptosis.2005

    • Author(s)
      Kimura S, Ito C, Jyoko N, Segawa H, Kuroda J, Okada M, Adachi S, Nakahata T, Yuasa T, Filho VC, Furukawa H, Maekawa T.
    • Journal Title

      Int J Cancer 113

      Pages: 158-165

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591005
  • [Journal Article] Zoledronic acid mediates Ras-independent growth inhibition of prostate cancer cells.2005

    • Author(s)
      Nogawa M, Yuasa T, Kimura S, Kuroda J, Segawa H, Sato K, Koizumi M, Maekawa T.
    • Journal Title

      Oncol Res 15

      Pages: 1-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591005
  • [Journal Article] Rapid quanfitation of IgG antibodies specific for blood group antigens A and B by surface plasmon resonanse..2005

    • Author(s)
      Kimura S
    • Journal Title

      Transfusion 45

      Pages: 56-62

    • Data Source
      KAKENHI-PROJECT-17659165
  • [Journal Article] A third generation bisphosphonate, minodronic acid (YM529), augments the interferon α/β-mediated inhibition of renal cell cancer cell growth both in vitro and in vivo.2005

    • Author(s)
      Yuasa T, Nogawa M, Kimura S, Yokota A, Sato K, Segawa H, Kuroda J, Maekawa T.
    • Journal Title

      Clin Cancer Res 11

      Pages: 853-859

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591005
  • [Journal Article] Rapid Quantitation of IgG Antibodies Specific for Blood Group Antigens A and B by Surface Plasmon Resonance.2005

    • Author(s)
      Kimura S
    • Journal Title

      Transfusion 45

      Pages: 56-62

    • Data Source
      KAKENHI-PROJECT-16659254
  • [Journal Article] NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia.2005

    • Author(s)
      Kimura, S
    • Journal Title

      Blood 106・12

      Pages: 3948-3954

    • Data Source
      KAKENHI-PROJECT-16659254
  • [Journal Article] Inhibition of leukemic cell growth by a novel anti-cancer drug (GUT-70) from Calophyllim brasiliense that acts by induction of apoptosis2005

    • Author(s)
      Kimura S
    • Journal Title

      International Journal of Cancer 113

      Pages: 158-165

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591005
  • [Journal Article] Inhibition of leukemic cell growth by a novel anti-cancer drug (GUT-70) from Calophyllim brasiliense that acts by induction of apoptosis2005

    • Author(s)
      Kimura S
    • Journal Title

      International Journal of Cancer 113

      Pages: 158-165

    • Data Source
      KAKENHI-PROJECT-16659438
  • [Journal Article] Inhibition of leukemic cell growth by a novel anti-cancer drug (GUT-70) from Calophyllim brasiliense that acts by induction of apoptosis.2005

    • Author(s)
      Kimura, S
    • Journal Title

      Int J Cancer 113・1

      Pages: 158-165

    • Data Source
      KAKENHI-PROJECT-16659254
  • [Journal Article] Inhibition of leukemic cell growth by a novel anti-cancer drug (GUT-70) from Calophyllim brasiliense that acts by induction of apoptosis2005

    • Author(s)
      Kimura S
    • Journal Title

      International Journal of Cancer 113

      Pages: 158-165

    • Data Source
      KAKENHI-PROJECT-16659254
  • [Journal Article] Cytotoxic effects of γδ T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy.

    • Author(s)
      Sato K, Kimura S, Segawa H, Yokota A, Matsumoto S, Kuroda J, Nogawa M, Yuasa T, Kiyono Y, Wada H, Maekawa T.
    • Journal Title

      Int J Cancer (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591005
  • [Patent] がん治療医薬組成物2022

    • Inventor(s)
      木村晋也、久保田寧、本山敬一、東大志、有馬英俊
    • Industrial Property Rights Holder
      木村晋也、久保田寧、本山敬一、東大志、有馬英俊
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Patent] 慢性骨髄性白血病幹細胞阻害剤2022

    • Inventor(s)
      木村晋也、渡邉達郎、山本雄大、嬉野博志、蒲池和晴、倉橋祐樹
    • Industrial Property Rights Holder
      木村晋也、渡邉達郎、山本雄大、嬉野博志、蒲池和晴、倉橋祐樹
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Patent] DNMT阻害剤の用途2020

    • Inventor(s)
      木村晋也、渡邊達郎、嬉野博志、蒲池和晴、酒向孫市、倉橋祐樹
    • Industrial Property Rights Holder
      木村晋也、渡邊達郎、嬉野博志、蒲池和晴、酒向孫市、倉橋祐樹
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Patent] 成人T細胞白血病/リンパ腫の検出方法2020

    • Inventor(s)
      木村晋也、末岡榮三朗、渡邉達郎、嬉野博志
    • Industrial Property Rights Holder
      木村晋也、末岡榮三朗、渡邉達郎、嬉野博志
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Patent] 医薬組成物2020

    • Inventor(s)
      木村晋也、酒向孫市、杉山晋平、倉橋裕樹、脇田弘臣
    • Industrial Property Rights Holder
      木村晋也、酒向孫市、杉山晋平、倉橋裕樹、脇田弘臣
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Acquisition Date
      2022
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Patent] 血液がんの診断および治療方法2020

    • Inventor(s)
      木村晋也、渡邉達郎、山本雄太、倉橋祐樹、酒向孫市、脇田弘臣
    • Industrial Property Rights Holder
      木村晋也、渡邉達郎、山本雄太、倉橋祐樹、酒向孫市、脇田弘臣
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-102904
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Patent] 成人T細胞性白血病/リンパ腫の検出方法2019

    • Inventor(s)
      渡邊達郎、末岡榮三郎、木村晋也、嬉野博志
    • Industrial Property Rights Holder
      渡邊達郎、末岡榮三郎、木村晋也、嬉野博志
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17K09908
  • [Patent] 細胞培養容器及びその容器を用いた細胞培養方法2010

    • Inventor(s)
      務中達也(島津製作所)、阿部浩久(島津製作所)、叶井正樹(島津製作所)、明地将一(島津製作所)、前川平、木村晋也(佐賀大学)、芦原英司(京都府立医科大学)、庄子習一(早稲田大学)、川合健太郎(早稲田大学)
    • Industrial Property Rights Holder
      務中達也(島津製作所)、阿部浩久(島津製作所)、叶井正樹(島津製作所)、明地将一(島津製作所)、前川平、木村晋也(佐賀大学)、芦原英司(京都府立医科大学)、庄子習一(早稲田大学)、川合健太郎(早稲田大学)
    • Filing Date
      2010-09-08
    • Data Source
      KAKENHI-PROJECT-21390293
  • [Patent] 細胞培養容器及びその容器を用いた細胞培養方法2010

    • Inventor(s)
      務中達也、阿部浩久、叶井正樹、明地将一、前川平、木村晋也、芦原英司、庄子習一、川合健太郎
    • Industrial Property Rights Holder
      島津製作所、京都大学、早稲田大学
    • Industrial Property Number
      2010-200679
    • Filing Date
      2010-09-08
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Patent] 細胞運動評価用マイクロ反応装置2009

    • Inventor(s)
      務中達也、阿部浩久、叶井正樹、前川平、木村晋也、芦原英司、庄子習一
    • Industrial Property Rights Holder
      島津製作所、京都大学、早稲田大学
    • Industrial Property Number
      2009-148339
    • Filing Date
      2009-06-23
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Patent] 新規ユビキリン結合性小分子2007

    • Inventor(s)
      木村晋也
    • Industrial Property Rights Holder
      京大TLO
    • Industrial Property Number
      2007-287570
    • Filing Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Patent] 新規ユビキリン結合性小分子2007

    • Inventor(s)
      木村晋也、他4名
    • Industrial Property Rights Holder
      京都大学
    • Industrial Property Number
      2007-287570
    • Filing Date
      2007-11-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Patent] 変異の検出方法2006

    • Inventor(s)
      木村晋也、前川平、平井光春、間嶋智史
    • Industrial Property Rights Holder
      京都大学、アークレイ株式会社
    • Filing Date
      2006-08-08
    • Data Source
      KAKENHI-PROJECT-18390283
  • [Patent] 変異の検出方法2006

    • Inventor(s)
      木村晋也、他3名
    • Industrial Property Rights Holder
      京都大学
    • Industrial Property Number
      2006-216194
    • Filing Date
      2006-08-08
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Patent] 膀胱表在性癌の治療又は予防用医薬組成物、及びその利用2004

    • Inventor(s)
      前川 平, 木村晋也
    • Industrial Property Rights Holder
      前川 平, 木村晋也
    • Filing Date
      2004-11-22
    • Data Source
      KAKENHI-PROJECT-16659254
  • [Patent] 膀胱表在性癌の治療又は予防剤、及び膀胱表在性癌の治療又は予防方法2004

    • Inventor(s)
      前川 平, 湯浅 健, 木村 晋也, 野河 正輝
    • Industrial Property Rights Holder
      前川 平, 湯浅 健, 木村 晋也, 野河 正輝
    • Industrial Property Number
      2004-282803
    • Filing Date
      2004-09-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591005
  • [Presentation] Development of a Perioperative Medication Suspension Decision Algorithm Based on Bayesian Networks2024

    • Author(s)
      Shuhei Kawaguchi, Osamu Fukuda, Sakiko Kimura, Wen Liang Yeoh, Nobuhiko Yamaguchi, Hiroshi Okumura
    • Organizer
      Proceedings of 2024 IEEE/SICE International Symposium on System Integration (SII)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06769
  • [Presentation] CMLの育薬2023

    • Author(s)
      木村晋也
    • Organizer
      第27回造血腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Presentation] Targets of Metabolic Alteration in Venetoclax / Decitabine Resistant Acute Myeloid Leukemia.2023

    • Author(s)
      Kotoko Yamatani, Tatsuro Watanabe, Kaori Saito, Abhishek Maiti, Satoshi Yamashita, Abdullah Khasawneh, Faith Jessica Paran, Kala Hayes, Gautam Borthakur, Joe R Harman, Shinya Kimura, Courtney DiNardo, Thomas Milne, Michael Andreeff, Yoko Tabe, Marina Konopleva
    • Organizer
      .65th American Society of Hematology Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24235
  • [Presentation] ベイジアンネットワークに基づく周術期休薬判断アルゴリズムの構築2023

    • Author(s)
      川口 修平, 木村 早希子, Yeoh Wen Liang, 山口 暢彦, 奥村 浩, 福田 修
    • Organizer
      2023年度電気・情報関係学会九州支部連合大会(第76回連合大会)
    • Data Source
      KAKENHI-PROJECT-22K06769
  • [Presentation] CML治療に残された課題2022

    • Author(s)
      木村晋也
    • Organizer
      第84回 日本血液学会 モーニングセミナー
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Presentation] Biomarkers of clinical resistance to Decitabine and Venetoclax therapy inferred by transcriptome and methylation analyses2022

    • Author(s)
      Kotoko Yamatani, Abhishek Maiti, Tatsuro Watanabe, Kaori Saitoh, Kala Hayes, Kanako Kinjo, Kazuho Ikeo, Takashi Miida, Shinya Kimura,Courtney D. DiNardo, Su Xiaoping, Yoko Tabe, Marina Konopleva
    • Organizer
      64th American Society of Hematology Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24235
  • [Presentation] 臨床に基づいた創薬2022

    • Author(s)
      木村晋也
    • Organizer
      第17回 日本がん分子標的治療学会TRワークショップ
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Presentation] Issues and future directions of academia-pharma collaborations for novel drug development2021

    • Author(s)
      木村晋也
    • Organizer
      日本癌学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Presentation] Chronic myeloid leukemia, Achievements and Limitations of tyrosine kinase inhibitors, and “Beyond”2021

    • Author(s)
      Shinya Kimura
    • Organizer
      Korean Society of Hematology (KSH) International Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Presentation] 経口可能なメチル化阻害剤の開発2020

    • Author(s)
      木村晋也
    • Organizer
      日本がん分子標的治療学会TRワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Presentation] Chronic myeloid leukemia, Achievements and Limitations of tyrosine kinase inhibitors, and “Beyond”2020

    • Author(s)
      木村晋也
    • Organizer
      日本癌治療学会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Presentation] A Novel Oral Demethylating Agent, OR-2100, in Combination with Tyrosine Kinase Inhibitors Overcomes Resistance in Chronic Myeloid Leukemia2020

    • Author(s)
      蒲池和晴、木村晋也
    • Organizer
      22nd Annual John Goldman E-Conference on Chronic Myeloid Leukemia: Biology and Therapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08756
  • [Presentation] Achievements and limitations of tyrosine kinase inhibitors, and development of demethylating agents2019

    • Author(s)
      Shinya Kimura
    • Organizer
      The 16th Nikko International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09908
  • [Presentation] ニロチニブのデータを用いた慢性骨髄性白血病治療における長期無治療寛解による財政影響分析2019

    • Author(s)
      木村晋也
    • Organizer
      日本血液学会総会
    • Data Source
      KAKENHI-PROJECT-17K09908
  • [Presentation] Targeting BCR-ABL by DNA/RNA heteroduplex oligonucleotide2018

    • Author(s)
      Kimura S, Hosiko T, Yano J, et al.
    • Organizer
      John Goldman CML conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09908
  • [Presentation] Imatinib STop Study Feasible to Japanese Clinical Setting2018

    • Author(s)
      Usuki K, Ueda T, Kimura S et al.
    • Organizer
      European Hematology Association
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09908
  • [Presentation] Administration of tocilizumab and etanercept for severe cytokine release syndrome (CRS) with thrombotic microangiopathy after HLA-haploidentical allogeneic peripheral blood stem cell transplantation.2017

    • Author(s)
      木塚遥菜、進藤岳郎、安藤寿彦、佐野晴彦、久保田寧、小島研介、木村晋也
    • Organizer
      第39回日本造血細胞移植学会総会
    • Place of Presentation
      松江市
    • Year and Date
      2017-03-02
    • Data Source
      KAKENHI-PROJECT-26461451
  • [Presentation] Allelic polymorphisms of KIR and HLA predict favorable responses to tyrosine kinase inhibitor in chronic myeloid leukemia2017

    • Author(s)
      Shinya Kimura
    • Organizer
      19th John Goldman CML conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09908
  • [Presentation] TCR Repertoire, Effector Regulatory T cells and KIR Genotyping Uncover Immunological Dynamics in Mogamulizumab-treated ATL2017

    • Author(s)
      Shindo T, Kusunoki Y, Kitaura K, Nishikawa H, Watanabe N, Ureshino H, Miyahara M, Watanabe T, Sueoka E, Espinoza LJ, Takami A, Ichinohe T, Suzuki R, Tanaka H, Saji H, Kimura S
    • Organizer
      The 18th International Conference on Human Retrovirology: HTLV and Related Viruses
    • Place of Presentation
      東京都
    • Year and Date
      2017-03-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461451
  • [Presentation] 肺扁平上皮癌におけるDiscoidin Domain Receptor 2の機能解析2016

    • Author(s)
      安部友範、中島千穂、渡邉直美、佐藤明美、木村晋也、荒金尚子
    • Organizer
      第57回日本肺癌学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2016-12-19
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] LC-MS/MSを用いた血漿中ファルネシルピロリン酸の定量とガン患者検体への応用.2016

    • Author(s)
      中川 沙織、不破 史子、荒金 尚子、佐藤 明美、木村 晋也、平山 哲、三井田 孝、大和 進
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      神奈川
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-24790175
  • [Presentation] Investigation of mechanism of lymphogenous metastasis using human lung cancer metastatic animal model2016

    • Author(s)
      Nakashima C, Sato A, Kimura S, Aragane N
    • Organizer
      75th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] Functional analysis of Discoidin domain receptor 2 mutation and expression in squamous cell lung cancer2016

    • Author(s)
      Sueoka-Aragane N, Watanabe N, Sato A, Watanabe T, Sueoka E, Kimura S
    • Organizer
      75th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] Functional analysis of Discoidin domain receptor 2 mutation and expression in squamous cell lung cancer2016

    • Author(s)
      Watanabe-Kobayashi N, Sato A, Watanabe T, Sueoka E, Kimura S, Sueoka-Aragane N
    • Organizer
      American Association for Cancer Research Annual Meeting 2016
    • Place of Presentation
      米国ニューオーリンズ
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] 血漿を用いたEGFR-TKIs獲得耐性機序の解明2016

    • Author(s)
      中村朝美、小林直美、梅口仁美、小宮一利、木村晋也、荒金尚子
    • Organizer
      第14回日本臨床腫瘍学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2016-07-28
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] LC-MS/MSを用いた血漿中ファルネシルピロリン酸の高感度定量2016

    • Author(s)
      大和 進、中川 沙織、不破 史子、木村 晋也、平山 哲、三井田 孝
    • Organizer
      第26回生物試料分析科学会年次学術集会
    • Place of Presentation
      沖縄
    • Year and Date
      2016-02-21
    • Data Source
      KAKENHI-PROJECT-24790175
  • [Presentation] 高感度EGFR遺伝子変異検出法におけるDNA自動抽出装置の有用性2016

    • Author(s)
      中島 千穂、安部 友範、佐藤 明美、加藤 潤一、末岡栄三朗、木村 晋也、荒金尚子
    • Organizer
      第57回日本肺癌学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2016-12-19
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] Monitoring of molecules related with acquired resistance to EGFR-TKI using metastatic animal model human lung cancer2015

    • Author(s)
      Akemi Sato, Naoko Sueoka-Aragane, Naomi Kobayashi, Tatsuro Watanabe, Eisaburo Sueoka, Seiji Okada, Shinya Kimura
    • Organizer
      74th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] The MEK inhibitior Trametinib selectively suppresses GVHD, while sparing GVT effects.2015

    • Author(s)
      板村英和、進藤岳郎、俵功、刈谷龍昇、岡田誠治、木村晋也
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢市
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-26461451
  • [Presentation] 血漿を用いたafatinib再投与効果予測因子の検討2015

    • Author(s)
      中村朝美、荒金尚子、小宮一利、小林直美、林真一郎、木村晋也
    • Organizer
      第55回日本呼吸器学会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2015-04-17
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] 成人T細胞白血病に対するモガムリズマブの効果は活性型NK細胞受容体とリガンドのマッチングによって予測できる可能性がある2015

    • Author(s)
      進藤岳郎、楠木靖史、嬉野博志、宮原正晴、渡邊達郎、末岡榮三朗、森脇祐司、吉田真一郎、一戸辰夫、Luis J Espinoza、高見昭良、田中秀則、佐治博夫、木村晋也
    • Organizer
      第24回日本組織適合性学会大会
    • Place of Presentation
      水戸市
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-26461451
  • [Presentation] ヒト肺がん転移モデルマウスを用いたEGF受容体チロシンキナーゼ阻害剤耐性機構のモニタリング2015

    • Author(s)
      佐藤明美、荒金尚子、小林直美、渡邉達郎、末岡栄三朗、岡田誠治、木村晋也
    • Organizer
      第19回日本がん分子標的治療学会
    • Place of Presentation
      松山全日空ホテル
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] Analysis of circulating plasma DNA on metastatic animal model using human lung cancer cell lines2015

    • Author(s)
      Naoko Sueoka-Aragane, Akemi Sato, Naomi Kobayashi, Eisaburo Sueoka, Seiji Okada, Shinya Kimura
    • Organizer
      American Association for Cancer Research Annual Meeting 2015
    • Place of Presentation
      Pennsylvania Convention Center
    • Year and Date
      2015-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] The MEK inhibitior Trametinib selectively suppresses Graft-versus-Host Disease (GVHD), while sparing Graft-versus-Tumor (GVT) effects.2015

    • Author(s)
      板村英和、進藤岳郎、久保田寧、木村晋也
    • Organizer
      がん分子標的治療学会学術集会
    • Place of Presentation
      松山市
    • Year and Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-26461451
  • [Presentation] 造血器腫瘍患者の中心静脈カテーテル関連血流感染症の発生に環境による違いはあるのか?2013

    • Author(s)
      北村浩晃、久保田寧、金子ゆかり、蒲池和晴、吉原麻里、板村英和、進藤岳郎、福島伯泰、安藤寿彦、末岡榮三朗、青木洋介、木村晋也
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] Deferasirox in iron-overloaded patients with hematologic diseases at Saga University Hospital2013

    • Author(s)
      Abe O, Yoshihara M, Kubota Y, Sueoka E, Kamachi K, Kitamura H, Itamura H, Nishi M, Shindo T, Fukushima N, Hamasaki Y, Kimura S
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] 輸血部門から院内医療安全管理委員会に報告した「インシデント・アクシデント」レポートの解析2013

    • Author(s)
      山田尚友, 山田麻里江, 東谷孝徳, 久保田寧, 木村晋也, 末岡榮三朗
    • Organizer
      第61回日本輸血・細胞治療学会総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] 不規則抗体が新生児に与える影響についての検討2013

    • Author(s)
      山田 麻里江, 山田 尚友, 東谷 孝徳, 久保田 寧, 木村 晋也, 末岡 榮三朗
    • Organizer
      日本輸血・細胞治療学会九州支部会第59回総会・第80回例会
    • Place of Presentation
      別府国際コンベンションセンター国際会議室
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] 成人血球貪食性リンパ組織球症の診断契機と治療2013

    • Author(s)
      吉村麻里子, 板村英和, 横尾眞子, 出勝, 久富崇, 久保田寧, 福島伯泰, 末岡榮三朗, 木村晋也
    • Organizer
      第53回日本リンパ網内系学会総会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] 2-Hydroxypropyl-b-cyclodextrin の抗白血病効果2013

    • Author(s)
      木村晋也、横尾眞子、久保田 寧、持永早希子、藤戸 博、東 大志、本山敬一、有馬英俊、入江徹美
    • Organizer
      シクロデキストリン学会
    • Place of Presentation
      熊本
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461425
  • [Presentation] Zoledronic acid significantly enhances radiation-induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling2013

    • Author(s)
      Koto K, Murata H, Matsui TA, Horie N, Sawai Y, Ashihara E, Kimura S, Maekawa T, Fushiki S, Horii M, Kubo T
    • Organizer
      International Society of Limb Salvage 17th General Meeting
    • Place of Presentation
      Bologna, Italy
    • Data Source
      KAKENHI-PROJECT-23592196
  • [Presentation] Therapeutic management in cardiac lymphoma2013

    • Author(s)
      Yoshihara M, Itamura H, Fukushima N, Kamach K, Kitamura H, Shindo T, Kubota Y, Sueoka E, Ichinohe T, Kimura S
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      仙台国際センター、東北大学百周年記念会館川内萩ホール
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] 電子カルテと輸血管理システムの連携による輸血後鉄過剰症モニタリングプログラムの運用2013

    • Author(s)
      末岡榮三朗, 山田尚友, 山田麻里江, 久保田寧, 福島伯泰, 東谷孝徳, 木村晋也
    • Organizer
      第61回日本輸血・細胞治療学会総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] Therapeutic management of cardiac lymphoma.2013

    • Author(s)
      Yoshihara M, Itamura H, Fukushima N, Kamachi K, Kitamura H, Shindo T, Kubota Y, Sueoka E, Ichinohe T, Kimura S.
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] Deferasirox in iron -overloaded patients with hematopoietic diseased at Saga University Hospital.2013

    • Author(s)
      Abe O, Yoshihara M, Kubota Y, Sueoka E, Kamachi K, Kitamura H, Itamura H, Nishi M, Shindo T, Fukushima N, Hamazaki Y, Kimura S.
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] 10 cases of mogamulizumab treatment for adult T-cell leukemia in Saga prefecture.2013

    • Author(s)
      Ureshino H, Miyahara M, Kamachi K, Yoshihara M, Kitamura H, Itamura H, Yoshimura M, Yokoo M, Ide M, Kubota Y, Shindo T, Fukushima N, Sueoka E, Kimura S.
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] Efficacy of melphalan/predonisolone/borte-zomib (MPB) therapy for patients with multiple myeloma.2013

    • Author(s)
      Hisatomi T, Kondo S, Fukushima N, Matsuishi E, Kubota Y, Shindo T, Gondo H, Kimura S.
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] 造血器腫瘍患者の中心静脈カテーテル関連血流感染症の発生に環境による違いはあるのか?2013

    • Author(s)
      北村浩晃, 久保田寧, 金子ゆかり, 蒲池和晴, 吉原麻里, 板村英和, 進藤岳郎, 福島伯泰, 安藤寿彦, 末岡榮三朗, 青木洋介, 木村晋也
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] 不規則抗体が新生児に与える影響についての検討2013

    • Author(s)
      山田麻里江, 山田尚友, 東谷孝徳, 久保田寧, 木村晋也, 末岡榮三朗
    • Organizer
      第61回日本輸血・細胞治療学会総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] 血漿中イソプレノイドのLC-MS/MS高感度定量2013

    • Author(s)
      中川 沙織、平山 哲、木村 晋也、三井田 孝、大和 進
    • Organizer
      第53回日本臨床化学会年次学術集会
    • Place of Presentation
      あわぎんホール (徳島市、徳島県)
    • Data Source
      KAKENHI-PROJECT-24790175
  • [Presentation] The third-generation bisphosphonate shows combined effects with anti-tumor drugs in human fibrosarcoma cells2013

    • Author(s)
      Murata H, Koto K, Sawai Y, Matsui TA, Horie N, Fushiki S, Kimura S, Maekawa T, Horii M, Kubo T
    • Organizer
      International Society of Limb Salvage 17th General Meeting
    • Place of Presentation
      Bologna, Italy
    • Data Source
      KAKENHI-PROJECT-23592196
  • [Presentation] 電子カルテと輸血管理システムの連携による輸血後鉄過剰症モニタリングプログラムの運用2013

    • Author(s)
      末岡 榮三朗, 山田 尚友, 山田 麻里江, 久保田 寧, 福島 伯泰, 東谷 孝徳, 木村 晋也
    • Organizer
      第61回 日本輸血・細胞治療学会 総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] HTLV-1専門外来におけるカウンセリング体制の整備と運用状況2013

    • Author(s)
      柘植薫, 久保田, 福島伯, 一戸辰夫, 木村晋也, 末岡榮三朗
    • Organizer
      第61回日本輸血・細胞治療学会総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] HTLV-1専門外来におけるカウンセリング体制の整備と運用状況2013

    • Author(s)
      柘植 薫, 久保田 寧, 福島 伯泰, 一戸 辰夫, 木村 晋也, 末岡 榮三朗
    • Organizer
      第61回 日本輸血・細胞治療学会 総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] 輸血部門から院内医療安全管理委員会に報告した「インシデント・アクシデント」レポートの解析2013

    • Author(s)
      山田 尚友, 山田 麻里江, 東谷 孝徳, 久保田 寧, 木村 晋也, 末岡 榮三朗
    • Organizer
      日本輸血・細胞治療学会九州支部会第59回総会・第80回例会
    • Place of Presentation
      別府国際コンベンションセンター国際会議室
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] A case of anaplastic large cell lymphoma, ALK-with T-LGL leukemia expressing aberrant phenotype.2013

    • Author(s)
      Kamachi K, Fukushima N, Kitamura H, Yoshihara M, Itamura H, Yoshimura M, Yokoo M, Ide M, Shindo T, Kubota Y, Ando T, Ichinohe T, Sueoka E, Ohshima K, Kimura S.
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] Hairy cell leukemia variantに間質性肺炎を合併した2例2013

    • Author(s)
      峯崎晃充、北村浩晃、久保田寧、進藤岳郎、久富崇、高橋浩一郎、蒲池和晴、吉原麻里、板村英和、福島伯泰、末岡榮三朗、木村晋也
    • Organizer
      第3回日本血液学会九州地方会
    • Place of Presentation
      アクロス福岡
    • Data Source
      KAKENHI-PROJECT-25670452
  • [Presentation] Combined effects of the Third-Generation Bisphosphonate and Radiation on Fibrosarcoma Cells2012

    • Author(s)
      Koto K, Murata H, Sakabe T, Matsui TA, Horie N, Sawai Y, Ashihara E, Kimura S, Maekawa T, Fushiki S, Kubo T
    • Organizer
      13th EFORT Congress
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-23592196
  • [Presentation] 新規HSP90阻害剤の発見と創薬展開2011

    • Author(s)
      木村晋也
    • Organizer
      化学療法基盤支援第2回シンポジウム
    • Place of Presentation
      横浜市
    • Year and Date
      2011-02-22
    • Data Source
      KAKENHI-PROJECT-21591201
  • [Presentation] Wnt/ b-catenin signaling inhibitors in combination with TKI2011

    • Author(s)
      Kimura S.
    • Organizer
      13th Intrenational Conference on Chronic Myeloid Leukemia : Biology and Therapy
    • Place of Presentation
      Estoril, Portugal
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21591201
  • [Presentation] A Novel Automated Assay for the Detection of BCR-ABL Kinase Domain Mutations2010

    • Author(s)
      Tanaka R, Kimura S, Hosomi T, Hirai M, Nagao R, Takeuchi M, Yao H, Sakai K, HiraiH, Ashihara E, Maekawa T
    • Organizer
      15th Congress of the European Hematology Association(EHA)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-21390293
  • [Presentation] ABL tyrosine kinase inhibitors2010

    • Author(s)
      Kimura S.
    • Organizer
      The15th JFCR-International Symposium on Cancer Chemotherapy
    • Place of Presentation
      東京都
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-21591201
  • [Presentation] ABL tyrosine kinase inhibitors2010

    • Author(s)
      Kimura S
    • Organizer
      The 15th JFCR-International Symposium on Cancer Chemotherapy
    • Place of Presentation
      東京都
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-21591201
  • [Presentation] Detection of a point mutation in JAK2 DNA related to myelopoietic diseases by ENA modified pyrene-labeled RNA probe2010

    • Author(s)
      村上章、新井太一朗、田中瑠璃子、山吉麻子、小堀哲生、木村晋也、前川平
    • Organizer
      37th International Symposium on Nucleic Acid Chemistry
    • Place of Presentation
      はぎまんホール・ヴァイアマーレ、神奈川県
    • Year and Date
      2010-11-10
    • Data Source
      KAKENHI-PROJECT-21350093
  • [Presentation] T315I遺伝子変異を持つCMLに対するオーロラキナーゼ阻害剤、AT9283の開発について2010

    • Author(s)
      木村晋也、前川平
    • Organizer
      平成22年度第1回合同班会議
    • Place of Presentation
      名古屋
    • Year and Date
      2010-06-19
    • Data Source
      KAKENHI-PROJECT-21390293
  • [Presentation] AV-65, a Novel inhibitor of the Wnt/β-catenin signaling pathway, inhibits the proliferation of myeloma cells.2009

    • Author(s)
      Yao H, Ashihara E, Nagao R, Kimura S, Hirai H, Strovel JW, Padia J, Cholody WM, Maekawa T
    • Organizer
      The 51st American Society of Hematology Annual Meeting and Exposition
    • Place of Presentation
      New Orleans, USA.
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Presentation] 骨肉腫細胞に対する第3世代ビスフォスフォネートの転移抑制効果2009

    • Author(s)
      小藤和孝, 村田博昭, 堀江直行, 坂部智哉, 松井隆明, 木村晋也, 前川平, 伏木信次, 久保俊一
    • Organizer
      第18回がん転移学会学術集会
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20591764
  • [Presentation] Automated and Rapid Detection of BCR-ABL Kinase Domain Mutations in IM Resistant Patients with Ph+ Leukemias2009

    • Author(s)
      Tanaka R, Kimura S, Hosomi T, Hirai M, Nagao R, Yokota A, Takeuchi M, Yao H, Sakai K, Adachi S, Hirai H, Ashihara E, Maekawa T
    • Organizer
      The American Society of Hematology 51st Annual Meeting and Exposition(ASH)
    • Place of Presentation
      Ernest N. Morial Convention Center, New Orleans, USA
    • Year and Date
      2009-12-06
    • Data Source
      KAKENHI-PROJECT-21390293
  • [Presentation] Overcoming CML with T315I Mutation~Detection and Therapeutics~. Kyoto University Global COE2009

    • Author(s)
      Tanaka R, Kimura S, Nagao R, Yokota A, Takeuchi M, Yao H, Sakai K, Hirai H, Ashihara E, Maekawa T
    • Organizer
      Center for Frontier Medicine International Symposium/Retreat
    • Place of Presentation
      Hyogo, Japan
    • Year and Date
      2009-11-07
    • Data Source
      KAKENHI-PROJECT-21390293
  • [Presentation] ABL阻害剤の新展開2009

    • Author(s)
      木村晋也
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都市
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-21591201
  • [Presentation] CREB Is Involved in the Regulation of C/EBP & beta ; During'emergency' Granulopoiesis2009

    • Author(s)
      Hirai H, Kamio N, Matsusue A, Ogino S, Kimura N, Satake S, Ashihara E, Maekawa T, Tenen DG, Imanishi J
    • Organizer
      The American Society of Hematology 51st Annual Meeting and Exposition
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-21390293
  • [Presentation] Hypoxia-Adapted CML cells are more primitive population and are Eradication by Glyoxalase-1 Inhibitors2009

    • Author(s)
      Takeuchi M, Kimura S, Kuroda J, Ashihara E, Kawatani M, Osada H, Umezawa K, Yasui E, ImotoM, Tsuruo T, Yokota A, Tanaka R, Nagao R, Nakahata T, Fujiyama Y, MaekawaT
    • Organizer
      The American Society of Hematology 51st Annual Meeting and Exposition(ASH)
    • Place of Presentation
      Ernest N. Morial Convention Center, New Orleans, USA
    • Year and Date
      2009-12-06
    • Data Source
      KAKENHI-PROJECT-21390293
  • [Presentation] ヒト軟部肉腫細胞株に対する第3世代Bisphosphonate と放射線の併用効果に関する検討2009

    • Author(s)
      小藤和孝, 村田博昭, 坂部智哉, 劉和輝, 西垣泰典, 松井隆明, 堀江直行, 伏木信次, 木村晋也, 前川平, 久保俊一
    • Organizer
      第24回日本整形外科学会基礎学術集会
    • Year and Date
      2009-11-06
    • Data Source
      KAKENHI-PROJECT-20591764
  • [Presentation] The third-generation bisphosphonate inhibits tumor growth and lung metastasis in murine osteosarcoma cells.2009

    • Author(s)
      村田博昭, 小藤和孝, 堀江直行, 坂部智哉, 松井隆明, 伏木信次, 木村晋也,前川平, 久保俊一
    • Organizer
      The combined meeting of International Symposium of Limb Salvage and the Musculoskeletal Tumor Society
    • Data Source
      KAKENHI-PROJECT-20591764
  • [Presentation] マウス正所性膀胱がんモデルに対するγδT細胞局所注入療法2008

    • Author(s)
      木村晋也
    • Organizer
      第12回京都分子血液フォーラム
    • Place of Presentation
      京都
    • Year and Date
      2008-06-21
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Presentation] 薬物療法だけでCMLは完治できるのか〓2008

    • Author(s)
      木村晋也
    • Organizer
      第10回TOCHIGI HEMATOLOGY SEMINAR.
    • Place of Presentation
      宇都宮市
    • Year and Date
      2008-02-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] β-catenin siRNAによる骨髄腫増殖抑制効果2008

    • Author(s)
      芦原英司、河田英里、黒田純也、木村晋也、前川平
    • Organizer
      第12回がん分子標的治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Presentation] 滑膜肉腫細胞に対する第3 世代ビスホスフォネートの効果2008

    • Author(s)
      西垣泰典, 村田博昭, 小藤和孝, 堀江直行, 劉和輝, 竹下秀之, 木村晋也, 前川平, 伏木信次, 久保俊一
    • Organizer
      第41回日整会骨軟部腫瘍学術集会
    • Year and Date
      2008-07-18
    • Data Source
      KAKENHI-PROJECT-20591764
  • [Presentation] β-catenin siRNAによる骨髄腫増殖抑制効果2008

    • Author(s)
      木村晋也
    • Organizer
      第16回京都がん研究会
    • Place of Presentation
      京都
    • Year and Date
      2008-09-12
    • Data Source
      KAKENHI-PROJECT-20591121
  • [Presentation] 第3世代Bisphosphonate によるヒト線維肉腫細胞株に対する抗腫瘍効果に関する検討2008

    • Author(s)
      小藤和孝, 村田博昭, 木村晋也, 坂部智哉, 松井隆明, 堀江直行, 伏木信次, 前川平, 久保俊一
    • Organizer
      第23回日本整形外科学会基礎学術集会
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-20591764
  • [Presentation] Development of new tyrosine kinase inhibitors.2007

    • Author(s)
      Kimura S
    • Organizer
      Glasgow University, Haematology and Oncology Division Seminar
    • Place of Presentation
      イギリス・グラスゴー
    • Year and Date
      2007-02-13
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] CML治療における残された課題2007

    • Author(s)
      木村晋也
    • Organizer
      第1回 先進血液学レクチャー
    • Place of Presentation
      東京
    • Year and Date
      2007-11-13
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] 新規ABLチロシンキナーゼ阻害剤生き残るのはどれ〓2007

    • Author(s)
      木村晋也
    • Organizer
      第18回新薬創製談話会
    • Place of Presentation
      沼津市
    • Year and Date
      2007-09-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] 新規ABL阻害剤、dasatinib, nilotinib, INNO-406の比較検討2007

    • Author(s)
      木村晋也
    • Organizer
      第11回がん分子標的治療研究会総会
    • Place of Presentation
      大阪市
    • Year and Date
      2007-07-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] NO-406, from bench to Clinic2007

    • Author(s)
      Shinva, Kimura
    • Organizer
      International Conference on Chronic Myeloid Leukemia Prospects for the 21st Century
    • Place of Presentation
      Mandelieu, France
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] BCR-ABL陽性白血病細胞における新規ABL阻害剤INNO-406の細胞死誘導機序.(Mechanism of INNO-406-mediated cell death in Bcr-Abl^+ leukemic cells.)2007

    • Author(s)
      木村晋也
    • Organizer
      第66回日本癌学会学術総会English Workshop
    • Place of Presentation
      横浜市
    • Year and Date
      2007-10-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] ZOMETA TRIANGLE-骨髄腫治療の新しい可能性-2007

    • Author(s)
      木村晋也
    • Organizer
      ゾメタ適応拡大記念講演会
    • Place of Presentation
      山口市
    • Year and Date
      2007-04-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] 新規ABLチロシンキナーゼ阻害剤の開発状況.2007

    • Author(s)
      木村晋也
    • Organizer
      第8回 東海難治性血液腫瘍研究会
    • Place of Presentation
      名古屋市
    • Year and Date
      2007-06-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] How to treat CML patients in post imatinib era2007

    • Author(s)
      Kimura S
    • Organizer
      Frankfurt University Hospital, Leukemia Meeting
    • Place of Presentation
      ドイツ・フランクフルト
    • Year and Date
      2007-02-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] CMLを治す2007

    • Author(s)
      木村晋也
    • Organizer
      第1回 Meet the Expert in Fukui
    • Place of Presentation
      福井市
    • Year and Date
      2007-10-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] INNO-406, from bench to Clinic2007

    • Author(s)
      Kimura S
    • Organizer
      International Conference on CML prospects for 21st Century
    • Place of Presentation
      フランス・マンデリュー
    • Year and Date
      2007-09-29
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] Comparison of Imatinib, Dasatinib, Nilotinib and INNO-406 in Imatinib-Resistant Cell Lines.2007

    • Author(s)
      Kimura S
    • Organizer
      The American Society of Hematology 49th Annual Meeting and Exposition
    • Place of Presentation
      アメリカ・アトランタ
    • Year and Date
      2007-12-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] INNO-406, a novel Bcr-Abl/Lyn inhibitor.2007

    • Author(s)
      Kimura S
    • Organizer
      The San Antonio Cancer Institute Seminar Series
    • Place of Presentation
      アメリカ・サンアントニオ
    • Year and Date
      2007-03-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] INNO-406, from bench to Clinic.2007

    • Author(s)
      Kimura S
    • Organizer
      International Conference on Chronic Myeloid Leukemia Prospects for the 21st Century
    • Place of Presentation
      フランス・マンデリュー
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] 分子標的療法:白血病のあたらしい治療法を例に.2007

    • Author(s)
      木村晋也
    • Organizer
      第32回 東日本小児科学会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] INNO-406, a new dual Bcr-Abl/Lyn tyrosine kinase inhibitor.2007

    • Author(s)
      Kimura S
    • Organizer
      Heidelberg University, Oncology and Hematology Seminar
    • Place of Presentation
      ドイツ・マンハイム
    • Year and Date
      2007-02-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] INNO-406 Demonstrates Activity in Patients with Philadelphia Chromosome Positive Leukemias who are Intolerant or Resistant to Imatinib and Second Generation Tyrosine Kinase Inhibitors2007

    • Author(s)
      Le, Coutre, P., Kantarjian, H., Cortes, J., Nagler, A., Pinilla, J., Hochhause, A., Jones, D., Kimura, S., Craig, A., Carroll, E., Giampalmi, J., Ottmann, O
    • Organizer
      The American Society of Hematology 49th Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      2007-12-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] Comparison of Imatinib, Dasatinib, Nilotinib and INNO-406 in Imatinib-Resistant Cell Lines2007

    • Author(s)
      Kimura, S., Deguchi, X. Ashihara, E., Niwa, T., Hodohara, K., Fujiyama, Y., Maekawa, T
    • Organizer
      The American Society of Hematology 49th Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      2007-12-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] INNO-406, a new dual Bcr-Abl/Lyn tyrosine kinase inhibitor.2007

    • Author(s)
      Kimura S
    • Organizer
      MD Anderson Cancer Center, Leukemia Seminar
    • Place of Presentation
      アメリカ・ヒューストン
    • Year and Date
      2007-01-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] Glyoxalase-I Is a Potential Therapeutic Target for Chronic Myelogenous Leukemia Cells That Have Acquired Drug Resistance through Adaptation to Hypoxia2007

    • Author(s)
      Takeuchi M, Kuroda J, Kimura S, Ashihara E, Umezawa K, Yasui E, Kawatani M, Osada H, Hodohara K, Fujiyama Y, Maekawa T
    • Organizer
      The American Society of Hematology 49th Annual Meeting and Exposition(ASH)
    • Place of Presentation
      Georgia World Congress Center, Atlanta, Georgia, USA((Abstract #2931) Blood, 110:11(supple))(2007)
    • Year and Date
      2007-12-10
    • Data Source
      KAKENHI-PROJECT-18390283
  • [Presentation] ゾレドロン酸の抗腫瘍効果2007

    • Author(s)
      木村晋也
    • Organizer
      第8回 神戸骨転移セミナー
    • Place of Presentation
      神戸市
    • Year and Date
      2007-10-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] 分子標的治療における遺伝子検査の重要性2007

    • Author(s)
      木村晋也
    • Organizer
      ARKRAY遺伝子研究会
    • Place of Presentation
      京都市
    • Year and Date
      2007-09-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] Post imatinib era.2007

    • Author(s)
      Kimura S
    • Organizer
      Munich University, Haematology Labo Meeting.
    • Place of Presentation
      ドイツ・ミュンヘン
    • Year and Date
      2007-02-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] New tyrosine kinase inhibitors in the Treatment of Chronic Myeloid Leukemia.合同シンポジウム5「造血器腫瘍に対する分子標的療法の現状と展望」2007

    • Author(s)
      木村晋也
    • Organizer
      第68回日本血液学会・第48回日本臨床血液学会・合同総会(福岡)
    • Place of Presentation
      福岡市
    • Year and Date
      2007-10-13
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] Emerging treatment options in chronic myeloid leukemia.合同シンポジウム9「白血病に対する分子標的療法の新展開」2007

    • Author(s)
      木村晋也
    • Organizer
      第69回日本血液学会・第46回日本臨床血液学会・合同総会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-10-13
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] 骨転移治療におけるゾメタの位置づけ 〜患者QOLの向上を目指して〜2007

    • Author(s)
      木村晋也
    • Organizer
      郡山学術講演会
    • Place of Presentation
      郡山市
    • Year and Date
      2007-04-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] 新規dual Bcr-Abl/Lyn阻害剤NS-187によるimatinib mesylate耐性克服.2006

    • Author(s)
      木村晋也
    • Organizer
      第10回がん分子標的治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2006-06-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] CMLに対する分子標的治療2006

    • Author(s)
      木村晋也
    • Organizer
      第2回血液三都物語若手の会
    • Place of Presentation
      京都市
    • Year and Date
      2006-04-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] ZOMETA TRUANGLE-骨髄腫治療の新しい可能性2006

    • Author(s)
      木村晋也
    • Organizer
      ゾメタ適応拡大記念講演会
    • Place of Presentation
      福岡市
    • Year and Date
      2006-11-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] Block the Bcr-Abl signalin2006

    • Author(s)
      木村晋也
    • Organizer
      RCAIセミナー
    • Place of Presentation
      横浜市
    • Year and Date
      2006-02-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] 表面プラズモン共鳴によるIgG型抗A/B抗体価測定方法(第3報)2006

    • Author(s)
      木村晋也
    • Organizer
      第54回日本輸血学会総会
    • Place of Presentation
      大阪市
    • Year and Date
      2006-06-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] ゾレドロン酸の抗腫瘍作用2006

    • Author(s)
      木村晋也
    • Organizer
      Bisphosphonate International Symposium"New strategy of management for myeloma bone disease"
    • Place of Presentation
      東京
    • Year and Date
      2006-05-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] Ph^+白血病に対する分子標的治療2006

    • Author(s)
      木村晋也
    • Organizer
      第3回JPLSG研究会
    • Place of Presentation
      名古屋市
    • Year and Date
      2006-06-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] Mission impossible 〓 移植なしでCMLを治せ2006

    • Author(s)
      木村晋也
    • Organizer
      第9回治験フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2006-11-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] BCR-ABL/Lyn阻害剤NS-187(INNO-406)の変異型BCR-ABLに対する効果.2006

    • Author(s)
      木村晋也
    • Organizer
      第65回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2006-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] Cyclosporin A, a P-gp inhibitor, augments the anti-central nervous system Ph+ leukemia effects of INNO-4062006

    • Author(s)
      Yokota, A., Kimura, S., Masuda, S., Ashihara, E., Urasaki, Y., Terui, Y., Ruthardt, M., Ueda, T., Hatake, K., Inui, K., Maekawa, T.
    • Organizer
      The American Society of Hematology 48th Annual Meeting and Exposition(ASH)
    • Place of Presentation
      Orange County Convention Center, Orlando, Frorida, USA(198)((Abstract#834)Blood108:11(supple))
    • Year and Date
      2006-12-12
    • Data Source
      KAKENHI-PROJECT-18390283
  • [Presentation] ポスト・イマチニブ時代2006

    • Author(s)
      木村晋也
    • Organizer
      第11回血液学フォーラム
    • Place of Presentation
      札幌市
    • Year and Date
      2006-11-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591056
  • [Presentation] Combined effects of the Third-Generation Bisphosphonate and Radiation on Fibrosarcoma Cells

    • Author(s)
      Koto K, Murata H, Sakabe T, Matsui TA, Horie N, Sawai Y, Ashihara E, Kimura S, Maekawa T, Fushiki S, Kubo T.
    • Organizer
      13th EFORT Congress 2012
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-23592196
  • [Presentation] Non-invasive monitoring system for acquired resistance to EGFR-tyrosine kinase inhibitors using circulating plasma DNA

    • Author(s)
      Naoko Sueoka-Aragane, Tomomi Nakamura, Akemi Sato, Naomi Kobayashi, Kentaro Iwanaga, Kazutoshi Komiya, Toshiya Hosomi, Mitsuharu Hirai, Eisaburo Sueoka, Seiji Okada, Shinya Kimura
    • Organizer
      73th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      横浜市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] Monitoring of metastasis by detection of EGFR mutation, T790M, with plasma using animal model for metastasis of human lung cancer

    • Author(s)
      Naoko Sueoka-Aragane, Akemi Sato, Naomi Kobayashi, Yumi Nagano, Eisaburo Sueoka, Seiji Okada, Shinya Kimura
    • Organizer
      American Association for Cancer Research Annual Meeting 2014
    • Place of Presentation
      米国サンディエゴ
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] Usefulness of peripheral blood for monitoring of acquired resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer

    • Author(s)
      Naomi Kobayashi, Naoko Sueoka-Aragane, Hitomi Umeguchi, Tomomi Nakamura, Akemi Sato, Kazutoshi Komiya, Yuji Takeda, Shinichiro Hayashi, Eisaburo Sueoka, Shinya Kimura
    • Organizer
      American Association for Cancer Research Annual Meeting 2014
    • Place of Presentation
      米国サンディエゴ
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] The MEK inhibitor trametinib selectively suppresses GHVD, while sparing GVT effects.

    • Author(s)
      Hidekazu Itamura, Takero Shindo, Isao Tawara, Ryusho Kariya, Seiji Okada, Krishna V Komanduri, Shinya Kimura
    • Organizer
      ASBMT/CIBMTR BMT Tandem Meetings
    • Place of Presentation
      San Diego, CA USA
    • Year and Date
      2015-02-11 – 2015-02-15
    • Data Source
      KAKENHI-PROJECT-26461451
  • [Presentation] Monitoring of EGFR T790M with plasma in lung cancer patients

    • Author(s)
      Yoshiko Urata, Naoko Sueoka-Aragane, Nobuyuki Katakami, Miyako Satouchi, Soichiro Yokota, Keisuke Aoe, Kentaro Iwanaga, Kojiro Otsuka, Shinya Kimura, Shunichi Negoro
    • Organizer
      39th ESMO Congress
    • Place of Presentation
      スペイン マドリード
    • Year and Date
      2014-09-26 – 2014-09-30
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] Monitoring of metastasis by detection of EGFR mutation, T790M, with plasma using animal model for metastasis of human lung cancer

    • Author(s)
      Naoko Sueoka-Aragane, Nobuyuki Katakami, Miyako Satouchi, Soichiro Yokota, Keisuke Aoe, Kentaro Iwanaga, Kojiro Otsuka, Shinya Kimura, Shunichi Negoro
    • Organizer
      2014 ASCO Annual Meeting
    • Place of Presentation
      米国シカゴ
    • Year and Date
      2014-05-30 – 2014-06-03
    • Data Source
      KAKENHI-PROJECT-26430144
  • [Presentation] Correlation between plasma DNA and tumor status in an animal model on metastasis of lung cancer

    • Author(s)
      Akemi Sato, Naoko Sueoka-Aragane, Naomi Kobayashi, Yumi Nagano, Eisaburo Sueoka, Seiji Okada, Shinya Kimura
    • Organizer
      73th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      横浜市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26430144
  • 1.  MAEKAWA Taira (80229286)
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    # of Collaborated Products: 45 results
  • 2.  ASHIHARA Eishi (70275197)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 38 results
  • 3.  Kubota Yasuhi (60570413)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 38 results
  • 4.  YUASA Takeshi (00314162)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 5.  安藤 寿彦 (30363097)
    # of Collaborated Projects: 3 results
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  • 6.  MURATA Hiroaki (90360031)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 7.  SHIMAZAKI Chihiro (50170931)
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  • 13.  HISATOMI Takashi (10398125)
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Products: 1 results

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