Fujita Tsuyoshi 藤田剛

… Alternative Names

藤田剛フジタツヨシ

FUJITA Tsuyoshi 藤田剛

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Researcher Number	80379883
Other IDs
Affiliation (Current)	2025: 愛知学院大学, 歯学部, 歯学部研究員
Affiliation (based on the past Project Information) *help	2023: 愛知学院大学, 歯学部, 歯学部研究員 2019 – 2021: 広島大学, 医系科学研究科(歯), 准教授 2016 – 2018: 広島大学, 医歯薬保健学研究科(歯), 准教授 2015 – 2016: 広島大学, 医歯薬保健学研究院(歯), 准教授 2014: 広島大学, 病院, 講師 … More 2012 – 2014: 広島大学, 大学病院, 講師 2012: 広島大学, 病院(歯), 講師 2007 – 2011: Hiroshima University, Hospital, Assistant Professor 2006: 広島大学, 病院・助手 2006: 広島大学, 病院, 助手 Less
Review Section/Research Field	Principal Investigator Periodontal dentistry / Periodontology Except Principal Investigator Periodontal dentistry / Basic Section 57030:Conservative dentistry-related / Periodontology / Morphological basic dentistry
Keywords	Principal Investigator IL-8 / 歯肉上皮細胞 / イルソグラジンマレイン酸 / 歯周病予防 / 歯周病予防薬 / E-cadherin / 細胞接着因子 / Aggregatibacter actinomycetemcomitans / マレイン酸イルソグラジン / IL-6 … More / SAA / CRP / 血清アミロイド　A / グリチルリチン / 歯周炎 / マウス / 血糖値 / RAGE / HMGB1 / サイトカイン / Porphyromonas gulae / 糖尿病 / 歯周病 / アポトーシスシグナル / TGF-betaレセプター / smad2リン酸化 / 歯周病原細菌 / ERK / smad2 / アポトーシス / 歯肉上皮 / claudin-1 / アジスロマイシン / 宿主防御機能制御 / 細胞間バリアー / adherence junction / tight junction / 42 Map kinase (ERK) / p44 / CXCL-1 / CINC-2α / ケモカイン / コネキシン43 / ZO-1 / クロ-ディン / オクルディン / A.actinomycetemcomitans / ラット好中球遊走因子(CINC-2) / IL-1β / ギャップジャンクション … More Except Principal Investigator 歯周炎 / 歯周組織再生 / NR4A1 / 薬物性歯肉増殖症 / 歯周病原細菌 / C-MSCs / 間葉系幹細胞集塊 / 関節リウマチ / HIF-1α / DEC1 / 間葉系幹細胞 / マウス / 歯周療法学 / LL37 / 歯肉上皮細胞 / 歯肉上皮 / 再生医療 / 歯周外科学 / 上皮間葉転換 / Mfa1線毛 / P. gingivalis / 歯周病 / 創薬スクリーニング / Nr4a1 / ブチリデンフタリド / 立体複合化 / iPS細胞 / 神経堤細胞由来間葉系幹細胞 / IL-6 / RNA binding protein / RNA安定化タンパク質 / シトルリン化タンパク質 / ケルセチン / 歯周病源細菌 / RNA結合タンパク質 / 歯学 / 歯肉増殖症 / メカニズム / 口腔病理学 / 胎盤細胞 / 血清抗体価 / 早産 / 歯性感染 / Porphyromonas gingivalis / 早産関連因子 / 歯周炎活動度 / PISA / Pg血清抗体価 / Galectin-3 / 早産マーカー / ３Dプリンター / 3Dプリンター / 立体組織化 / 3Dバイオプリンター / 立体化 / C-MSC / 細胞集塊 / 凍結保存 / 免疫制御能 / 立体組織 / LRG1 / osteogenesis / mesenchymal stem cell / hypoxia / clock genes / HIF1α / 骨分化 / 低酸素 / 時計遺伝子 / apoptosis / TGF-beta / smad2 / アポトーシス / E-cadherin / ペリオスチン / 再生３要素 / 再生3要素 / 細胞外基質 / 幹細胞 / 骨髄間葉系幹細胞 / 血管新生 / 歯周炎予防 / 抗菌ペプチド / ストレス / HPA-axis / グルココルチコイドレセプター / ZO-1 / dexamethasone / 歯週病原細菌 / 細胞間接着 / コルチゾール / コルチコステロイド結合蛋白 / siRNA / MyD-88 / c-Raf / trkB / Elk-1 / 42 / p44 / 抗炎症作用 / 骨・セメント質関連タンパク質 / セメント芽細胞 / 歯周組織 / 脳由来神経栄養因子 Less

Effects of three subtypes of Mfa1 fimbriae on epithelial-mesenchymal transition in periodontal tissue destruction.
- Principal Investigator
  
  菊池毅
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Aichi Gakuin University
To identify novel therapy drug of Drug induced gingival overgrowth targeting NR4A1 by drug screening
- Principal Investigator
  
  Shinji Matsuda
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
The induced RNA-binding protein, HuR targets of IL-6 mRNA and enhances its stabilization in periodontitis
- Principal Investigator
  
  Ouhara Kazuhisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
Development of periodontal tissue regenerative therapy by using neural crest-derived MSCs and cell clumps culture technique
- Principal Investigator
  
  Kurihara Hidemi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
An comprehensive study on the role of Galectin-3 in the preterm birth process induced by periodontitis
- Principal Investigator
  
  Miyauchi Mutsumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
Research to develop new therapy targeting NR4A1 for drug-induced gingival overgrowth
- Principal Investigator
  
  Matsuda Shinji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
Regulation of gingival epithelial cell's function suppresses systemic infection of periodontal pathogen.Principal Investigator
- Principal Investigator
  
  Tsuyoshi Fujita
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
The bidirectional effect of Leucine-rich alpha-2-glycoprotein 1 (LRG1) in rheumatoid arthritis and periodontitis
- Principal Investigator
  
  Ouhara Kazuhisa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
The development of periodontal regenerative cell therapy by using clumps of MSCs/ECM complexes
- Principal Investigator
  
  Hidemi Kuriha
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
Preventive method for periodontal disease by regulation of periostin
- Principal Investigator
  
  KURIHARA HIDEMI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontology
- Research Institution
  Hiroshima University
Usefulness of the complex consisting of three regenerative factors, which can be processed and shaped in vitro for regeneration of severely destructed periodontal tissues
- Principal Investigator
  
  SHIBA Hideki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
The regulatory mechanism of function on gingival epithelium by irsogladine maleatePrincipal Investigator
- Principal Investigator
  
  FUJITA TSUYOSHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
顎骨由来の骨髄間葉系幹細胞を利用した歯周組織再生療法の確立
- Principal Investigator
  
  河口浩之
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
Investigation of preventive method for periodontal disease by regulating gingival epithelial cell' s functionPrincipal Investigator
- Principal Investigator
  
  FUJITA Tsuyoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
Usefulness of LL37 as a multifunctional molecule for prevention of periodontal disease and periodontal tissue regeneration
- Principal Investigator
  
  SHIBA Hideki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
The anti-inflammatory effect of irsogladine maleate in human gingival tissue.Principal Investigator
- Principal Investigator
  
  FUJITA Tsuyoshi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
コルチコステロイド結合蛋白高発現と侵襲性歯周炎の感受性との関わりについて
- Principal Investigator
  
  栗原英見
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
脳由来神経栄養因子を用いた歯周組織再生療法の確立
- Principal Investigator
  
  KURIHARA HIDEMI
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
マレイン酸イルソグラジンを用いた歯肉上皮細胞の機能制御による歯周病予防法の開発Principal Investigator
- Principal Investigator
  
  藤田剛
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
Investigation of the mechanism of osteogenic induction by clock genes
- Principal Investigator
  
  FUJIOKA Daisuke, 岩田倫幸
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University

[Journal Article] Functional Regulatory Mechanisms Underlying Bone Marrow Mesenchymal Stem Cell Senescence During Cell Passages2021
- Author(s)
  Iwata T.、Mizuno N.、Ishida S.、Kajiya M.、Nagahara T.、Kaneda-Ikeda E.、Yoshioka M.、Munenaga S.、Ouhara K.、Fujita T.、Kawaguchi H.、Kurihara H.
- Journal Title
  
  Cell Biochemistry and Biophysics
  
  Volume: - Issue: 2 Pages: 321-336
- DOI
  10.1007/s12013-021-00969-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K18999
[Journal Article] The role of nuclear receptor 4A1 (NR4A1) in drug‐induced gingival overgrowth2021
- Author(s)
  Hatano Saki、Matsuda Shinji、Okanobu Ai、Furutama Daisuke、Memida Takumi、Kajiya Mikihito、Ouhara Kazuhisa、Fujita Tsuyoshi、Mizuno Noriyoshi、Kurihara Hidemi
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 7
- DOI
  10.1096/fj.202100032r
- Data Source
  KAKENHI-PROJECT-19K10130
[Journal Article] Aggressive periodontitis and NOD2 variants2020
- Author(s)
  Mizuno Noriyoshi, Kume Kodai, Nagatani Yukiko, Matsuda Shinji, Iwata Tomoyuki, Ouhara Kazuhisa, Kajiya Mikihito, Takeda Katsuhiro, Matsuda Yukiko, Tada Yui, Ohsawa Ryosuke, Morino Hiroyuki, Mihara Keichiro, Fujita Tsuyoshi, Kawaguchi Hiroyuki, Shiba Hideki, Kawakami Hideshi, Kurihara Hidemi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 65(10) Issue: 10 Pages: 841-846
- DOI
  10.1038/s10038-020-0777-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-18H02978, KAKENHI-PROJECT-18K09599
[Journal Article] IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier2020
- Author(s)
  Furutama Daisuke、Matsuda Shinji、Yamawaki Yosuke、Hatano Saki、Okanobu Ai、Memida Takumi、Oue Hiroshi、Fujita Tsuyoshi、Ouhara Kazuhisa、Kajiya Mikihito、Mizuno Noriyoshi、Kanematsu Takashi、Tsuga Kazuhiro、Kurihara Hidemi
- Journal Title
  
  Brain Sciences
  
  Volume: 10 Issue: 10 Pages: 679-679
- DOI
  10.3390/brainsci10100679
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599
[Journal Article] Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model2020
- Author(s)
  Hamamoto Yuta、Ouhara Kazuhisa、Munenaga Syuichi、Shoji Mikio、Ozawa Tatsuhiko、Hisatsune Jyunzo、Kado Isamu、Kajiya Mikihito、Matsuda Shinji、Kawai Toshihisa、Mizuno Noriyoshi、Fujita Tsuyoshi、Hirata Shintaro、Tanimoto Kotaro、Nakayama Koji、Kishi Hiroyuki、Sugiyama Eiji、Kurihara Hidemi
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 22 Issue: 1 Pages: 249-249
- DOI
  10.1186/s13075-020-02348-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K10072, KAKENHI-PROJECT-20K09921, KAKENHI-PROJECT-20K18537, KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-18H02689, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K18999, KAKENHI-PROJECT-19K24073
[Journal Article] Multiple External Root Resorption of Teeth as a New Manifestation of Systemic Sclerosis-A Cross-Sectional Study in Japan.2019
- Author(s)
  Memida T, Matsuda S, Kajiya M, Mizuno N, Ouhara K, Fujita T, Hirata S, Yoshida Y, Sugimoto T, Nishi H, Kawaguchi H, Sugiyama E, Kurihara H.
- Journal Title
  
  J Clin Med.
  
  Volume: Oct 4;8(10). Issue: 10 Pages: 1628-1628
- DOI
  10.3390/jcm8101628
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599
[Journal Article] Relationship between periodontal inflammation and calcium channel blockers induced gingival overgrowth?a cross-sectional study in a Japanese population2019
- Author(s)
  Matsuda Shinji、Okanobu Ai、Hatano Saki、Kajiya Mikihito、Sasaki Shinya、Hamamoto Yuta、Iwata Tomoyuki、Ouhara Kazuhisa、Takeda Katsuhiro、Mizuno Noriyoshi、Fujita Tsuyoshi、Kurihara Hidemi
- Journal Title
  
  Clinical Oral Investigations
  
  Volume: - Issue: 11 Pages: 4099-4105
- DOI
  10.1007/s00784-019-02846-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-16K11830
[Journal Article] Clumps of Mesenchymal Stem Cell/Extracellular Matrix Complexes Generated with Xeno-Free Conditions Facilitate Bone Regeneration via Direct and Indirect Osteogenesis2019
- Author(s)
  Motoike Souta、Kajiya Mikihito、Komatsu Nao、Horikoshi Susumu、Ogawa Tomoya、Sone Hisakatsu、Matsuda Shinji、Ouhara Kazuhisa、Iwata Tomoyuki、Mizuno Noriyoshi、Fujita Tsuyoshi、Ikeya Makoto、Kurihara Hidemi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 16 Pages: 3970-3970
- DOI
  10.3390/ijms20163970
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K10129, KAKENHI-PROJECT-19K19030, KAKENHI-PROJECT-18H02977, KAKENHI-PROJECT-18J13726
[Journal Article] Glycyrrhizic acid suppresses inflammation and reduces the increased glucose levels induced by the combination of Porphyromonas gulae and ligature placement in diabetic model mice2019
- Author(s)
  Akutagawa Keiichi、Fujita Tsuyoshi、Ouhara Kazuhisa、Takemura Tasuku、Tari Misako、Kajiya Mikihito、Matsuda Shinji、Kuramitsu Shohei、Mizuno Noriyoshi、Shiba Hideki、Kurihara Hidemi
- Journal Title
  
  International Immunopharmacology
  
  Volume: 68 Pages: 30-38
- DOI
  10.1016/j.intimp.2018.12.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-18H02977
[Journal Article] Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes2018
- Author(s)
  Komatsu Nao、Kajiya Mikihito、Motoike Souta、Takewaki Manabu、Horikoshi Susumu、Iwata Tomoyuki、Ouhara Kazuhisa、Takeda Katsuhiro、Matsuda Shinji、Fujita Tsuyoshi、Kurihara Hidemi
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 9 Issue: 1 Pages: 342-342
- DOI
  10.1186/s13287-018-1085-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-17K17351
[Journal Article] The involvement of C5a in the progression of experimental arthritis with Porphyromonas gingivalis infection in SKG mice2018
- Author(s)
  Munenaga Syuichi、Ouhara Kazuhisa、Hamamoto Yuta、Kajiya Mikihito、Takeda Katsuhiro、Yamasaki Satoshi、Kawai Toshihisa、Mizuno Noriyoshi、Fujita Tsuyoshi、Sugiyama Eiji、Kurihara Hidemi
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 20 Issue: 1
- DOI
  10.1186/s13075-018-1744-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09599
[Journal Article] Cryopreserved clumps of mesenchymal stem cell/extracellular matrix complexes retain osteogenic capacity and induce bone regeneration2018
- Author(s)
  Motoike Souta、Kajiya Mikihito、Komatsu Nao、Takewaki Manabu、Horikoshi Susumu、Matsuda Shinji、Ouhara Kazuhisa、Iwata Tomoyuki、Takeda Katsuhiro、Fujita Tsuyoshi、Kurihara Hidemi
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 9 Issue: 1 Pages: 73-73
- DOI
  10.1186/s13287-018-0826-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17351, KAKENHI-PROJECT-15H05053, KAKENHI-PROJECT-15K11390, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-18J13726
[Journal Article] Regulation of defensive function on gingival epithelial cells can prevent periodontal disease2018
- Author(s)
  Fujita　T., Yoshimoto T., Kajiya M., Ouhara K., Matsuda S., Takemura T., Akutagawa K., Takeda K., Mizuno N., Kurihara H.
- Journal Title
  
  Japanese Dental Science Review
  
  Volume: 印刷中 Issue: 2 Pages: 66-75
- DOI
  10.1016/j.jdsr.2017.11.003
- NAID
  50013109052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11389, KAKENHI-PROJECT-18K09599
[Journal Article] BDNF/HMW-HA complex as an adjunct to nonsurgical periodontal treatment of ligature-induced periodontitis in dogs2018
- Author(s)
  Sasaki Shinya、Takeda Katsuhiro、Takewaki Manabu、Ouhara Kazuhisa、Kajiya Mikihito、Mizuno Noriyoshi、Fujita Tsuyoshi、Kurihara Hidemi
- Journal Title
  
  Journal of Periodontology
  
  Volume: 90 Issue: 1 Pages: 98-109
- DOI
  10.1002/jper.18-0070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-16K11831
[Journal Article] Reparative bone-like tissue formation in the tooth of a systemic sclerosis patient2018
- Author(s)
  Matsuda S.、Memida T.、Mizuno N.、Ogawa I.、Ouhara K.、Kajiya M.、Fujita T.、Sugiyama E.、Kurihara H.
- Journal Title
  
  International Endodontic Journal
  
  Volume: 26-28 Issue: 9 Pages: 12914-12914
- DOI
  10.1111/iej.12914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11390, KAKENHI-PROJECT-18K09599
[Journal Article] The induced RNA-binding protein, HuR, targets 3′-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis2018
- Author(s)
  Ouhara K.、Munenaga S.、Kajiya M.、Takeda K.、Matsuda S.、Sato Y.、Hamamoto Y.、Iwata T.、Yamasaki S.、Akutagawa K.、Mizuno N.、Fujita T.、Sugiyama E.、Kurihara H.
- Journal Title
  
  Clinical & Experimental Immunology
  
  Volume: Feb Issue: 3 Pages: 325-336
- DOI
  10.1111/cei.13110
- Data Source
  KAKENHI-PROJECT-15K11390
[Journal Article] MSC/ECM cellular complexes induce periodontal tissue regeneration2017
- Author(s)
  Manabu Takewaki, Mikihito Kajiya*, Katsuhiro Takeda, Shinya Sasaki, Souta Motoike, Nao Komatsu, Shinji Matsuda, Kazuhisa Ouhara, Noriyoshi Mizuno, Tsuyoshi Fujita, and Hidemi Kurihara
- Journal Title
  
  Journal of Dental Research
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05053
[Journal Article] A novel gingival overgrowth mouse model induced by the combination of CsA and ligature-induced inflammation.2017
- Author(s)
  Okanobu A, Matsuda S, Kajiya M, Fujita T, Kittaka M, Shiba H, Kurihara H
- Journal Title
  
  Journal of Immunological Methods
  
  Volume: 印刷中 Pages: 31-36
- DOI
  10.1016/j.jim.2017.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11830
[Journal Article] Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration2017
- Author(s)
  Kei Takeshita, Souta Motoike1, Mikihito Kajiya, Nao Komatsu, Manabu Takewaki, Kazuhisa Ouhara, Tomoyuki Iwata, Katsuhiro Takeda, Noriyoshi Mizuno, Tsuyoshi Fujita, and Hidemi Kurihara
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 8:101 Issue: 1 Pages: 101-101
- DOI
  10.1186/s13287-017-0550-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H07004, KAKENHI-PROJECT-15K11215, KAKENHI-PROJECT-15K11390
[Journal Article] Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration2017
- Author(s)
  Kei Takeshita, Souta Motoike, Mikihito Kajiya, Nao Komatsu, Manabu Takewaki, Kazuhisa Ouhara, Tomoyuki Iwata, Katsuhiro Takeda, Noriyoshi Mizuno, Tsuyoshi Fujita, and Hidemi Kurihara
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05053
[Journal Article] MSC/ECM Cellular Complexes Induce Periodontal Tissue Regeneration.2017
- Author(s)
  Takewaki M, Kajiya M, Takeda K, Sasaki S, Motoike S, Komatsu N, Matsuda S, Ouhara K,
- Journal Title
  
  Journal of dental research
  
  Volume: 96(9) Issue: 9 Pages: 984-991
- DOI
  10.1177/0022034517708770
- Open Access
- Data Source
  KAKENHI-PROJECT-15K11215, KAKENHI-PROJECT-15K11390
[Journal Article] Porphyromonas gingivalis infection exacerbates the onset of rheumatoid arthritis in SKG mice.2016
- Author(s)
  Yamakawa M, Ouhara K, Kajiya M, Munenaga S, Kittaka M, Yamasaki S, Takeda K, Takeshita K, Mizuno N, Fujita T, Sugiyama E, Kurihara H.
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: Nov;186(2): Issue: 2 Pages: 177-189
- DOI
  10.1111/cei.12847
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15766, KAKENHI-PROJECT-16K20672, KAKENHI-PROJECT-15K11390
[Journal Article] Mobilization of TLR4 Into Lipid Rafts by Aggregatibacter Actinomycetemcomitans in Gingival Epithelial Cells.2016
- Author(s)
  Imai H, Fujita T, Kajiya M, Ouhara K, Yoshimoto T, Matsuda S, Takeda K, Kurihara H.
- Journal Title
  
  Cell Physiol Biochem.
  
  Volume: 39(5) Pages: 1777-1786
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K11390
[Journal Article] Azithromycin recovers reductions in barrier function in human gingival epithelial cells stimulated with tumor necrosis factor-alfa2016
- Author(s)
  Miyagawa T., Fujita T., Yumoto H., Yoshimoto T., Kajiya M., Ouhara K., Matsuda S., Shiba H., Matsuo T., Kurihara H.
- Journal Title
  
  Arch Oral Biol.
  
  Volume: 62 Pages: 64-69
- DOI
  10.1016/j.archoralbio.2015.11.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11389, KAKENHI-PROJECT-15K11390, KAKENHI-PROJECT-15K15766
[Journal Article] Houttunia Cordata suppressed the Aggregatibacter actinomycetemcomitans-induced increase of inflammatory-related genes in cultured human gingival epithelial cells.2015
- Author(s)
  Kabir MA., Fujita T., Ouhara K., Kajiya M., Matsuda S., Shiba H., Kurihara H.
- Journal Title
  
  Journal of Dental Sciences
  
  Volume: 10 Pages: 88-94
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24593123
[Journal Article] Clumps of a mesenchymal stromal cell/extracellular matrix complex can be a novel tissue engineering therapy for bone regeneration.2015
- Author(s)
  Kittaka M, Kajiya M, Shiba H, Takewaki M, Takeshita K, Khung R, Fujita T, Iwata T, Nguyen TQ, Ouhara K, Takeda K, Fujita T, Kurihara H.
- Journal Title
  
  Cytotherapy.
  
  Volume: 2 Issue: 7 Pages: 48-61
- DOI
  10.1016/j.jcyt.2015.01.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390467, KAKENHI-PROJECT-25862051, KAKENHI-PROJECT-26861814, KAKENHI-PROJECT-15H05053, KAKENHI-PROJECT-24593122
[Journal Article] Irsogladine maleate inhibits Porphyromonas gingivalis-mediated expression of toll-like receptor 2 and interleukin-8 in human gingival epithelial cells.2015
- Author(s)
  Savitri IJ., Ouhara K., Fujita T., Kajiya M., Miyagawa T., Kittaka M., Yamakawa M., Shiba H., Kurihara H.
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 印刷中 Issue: 4 Pages: 486-493
- DOI
  10.1111/jre.12231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593123
[Journal Article] Involvement of smad2 and Erk/Akt cascade in TGF-beta1-induced apoptosis in human gingival epithelial cells.2015
- Author(s)
  Yoshimoto T., Fujita T., Kajiya M., Matsuda S., Ouhara K., Shiba H., Kurihara H.
- Journal Title
  
  CYTOKINE
  
  Volume: 印刷中 Issue: 1 Pages: 165-173
- DOI
  10.1016/j.cyto.2015.03.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670885
[Journal Article] Amphotericin B down-regulates Aggregatibacter actinomycetemcomitans-induced production of IL-8 and IL-6 in human gingival epithelial cells.2014
- Author(s)
  Imai H., Fujita T., Kajiya M., Ouhara K., Miyagawa T., Matsuda S., Shiba H., Kurihara H.
- Journal Title
  
  Celler Immunology
  
  Volume: 290 Issue: 2 Pages: 201-208
- DOI
  10.1016/j.cellimm.2014.07.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24593123, KAKENHI-PROJECT-25862051
[Journal Article] Smad2 is involved in Aggregatibacter actinomycetemcomitans-induced apoptosis.2014
- Author(s)
  Yoshimoto T., Fujita T., Ouhara K., Kajiya M., Imai H., Shiba H., Kurihara H.
- Journal Title
  
  Journal of Dental Research
  
  Volume: 93 Issue: 11 Pages: 1148-1154
- DOI
  10.1177/0022034514550041
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24593123, KAKENHI-PROJECT-25862051
[Journal Article] Irsogladine maleate regulates the inflammatory related genes in human gingival epithelial cells stimulated by Aggregatibacter actinomycetemcomitans.2013
- Author(s)
  Miyagawa T
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 15 Issue: 2 Pages: 340-347
- DOI
  10.1016/j.intimp.2012.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390497, KAKENHI-PROJECT-22792085, KAKENHI-PROJECT-24593123, KAKENHI-PROJECT-24792330
[Journal Article] Antimicrobial peptide LL37 promotes vascular endothelial growth factor-A expression in human periodontal ligament cells.2013
- Author(s)
  Kittaka M
- Journal Title
  
  J Periodontal Res
  
  Volume: Apr;48(2) Issue: 2 Pages: 228-34
- DOI
  10.1111/j.1600-0765.2012.01524.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792085, KAKENHI-PROJECT-24593122
[Journal Article] The antimicrobial peptide LL37 promotes bone regeneration in a rat calvarial bone defect2013
- Author(s)
  Kittaka M., Shiba H., Kajiya M., Fuita T., Iwata T., Rathvisa K., Ouhara K., Takeda K., Fujita T., Komatsuzawa H., Kurihara, H.
- Journal Title
  
  Peptides
  
  Volume: 46 Pages: 136-42
- DOI
  10.1016/j.peptides.2013.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593122, KAKENHI-PROJECT-25862051
[Journal Article] Loss of claudin-1 in lipopolysaccharide-treated periodontal epithelium2012
- Author(s)
  Fujita T., et al
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 47 Issue: 2 Pages: 222-227
- DOI
  10.1111/j.1600-0765.2011.01424.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792087
[Journal Article] Smad2 is involved in the apoptosis of murine gingival junctional epithelium associated with inhibition of Bcl-2.2012
- Author(s)
  Fujita T.
- Journal Title
  
  Arch Oral Biol.
  
  Volume: Nov;57(11) Issue: 11 Pages: 1567-73
- DOI
  10.1016/j.archoralbio.2012.08.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792085, KAKENHI-PROJECT-24593123
[Journal Article] Loss of claudin-1 in lipopolysaccharide-treated periodontal epithelium2012
- Author(s)
  Fujita T., Firth JD., Kittaka M., 以下3名
- Journal Title
  
  J. Periodontal Res
  
  Volume: 47 Pages: 222-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792087
[Journal Article] Irsogladine maleate regulates epithelial barrier function in tumornecrosis factor-a-stimulated humangingival epithelial cells.2012
- Author(s)
  Fujita T., Yumoto H., Shiba H., 以下8名
- Journal Title
  
  J. Periodontal Res
  
  Volume: 47 Pages: 55-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792087
[Journal Article] Irsogladine maleate regulates epithelial barrier function in tumor necrosis factor-α-stimulated human gingival epithelial cells2012
- Author(s)
  Fujita T., et al
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 47 Pages: 55-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792087
[Journal Article] Irsogladine maleate regulates neutrophil migration and E-cadherin expression in gingival epithelium stimulated by Aggregatibacter actinomycetemcomitans2010
- Author(s)
  Fujita T., Kishimoto A., Shiba H
- Journal Title
  
  Biochemical Pharmacolgy 79
  
  Pages: 1496-1505
- NAID
  120003796888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791613
[Journal Article] Irsogladine maleate regulates neutrophil migration and E-cadherin expression in gingival epithelium stimulated by Aggregatibacter qctinomycetemcomitans.2010
- Author(s)
  藤田割, 他11名
- Journal Title
  
  Biochemical Pharmacology 79
  
  Pages: 1496-1505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791613
[Journal Article] The Antimicrobial Peptide LL37 Induces the Migration of Human Pulp Cells : A Possible Adjunct for Regenerative Endodontics.2010
- Author(s)
  Kajiya, M., Shiba, H., Komatsuzawa, H., Ouhara, K., Fujita, T., Takeda, K., Uchida, Y., Mizuno, N., Kawaguchi, H., Kurihara, H.
- Journal Title
  
  J Endod. 36
  
  Pages: 1009-1013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592430
[Journal Article] Irsogladine maleate counters the IL-1β-induced suppression in gap-junctional intercellular communication without affecting increased ZO-1 levels by IL-1β in human gingival epithelial cells2008
- Author(s)
  藤田剛
- Journal Title
  
  Journal of Periodontal Research 43
  
  Pages: 96-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18791595
[Journal Article] Irsogladine maleate counters the IL-1β-induced suppression in gap-junctional intercellular communication without affecting increased Z0-1 levels by IL-1β in human gingival epithelial cells
- Author(s)
  藤田剛
- Journal Title
  
  Journal of Periodontal Research (印刷中)
- Data Source
  KAKENHI-PROJECT-18791595
[Presentation] Serum antibody titer against FimA Type IV of Porphyromonas gingivalis is a possible marker for preterm birth cause by periodontitis:2018
- Author(s)
  Takagi H, Frusho H, Miyauchi M, Ohara K, Fujita T, Urabe S, Kurihara H, Kudo Y, Takata T
- Organizer
  第66回国際歯科研究学会日本部会総会・学術大会
- Data Source
  KAKENHI-PROJECT-16K11444
[Presentation] ３次元培養間葉系幹細胞集塊の細胞分化を制御するメカノトランスダクション機構の解析2017
- Author(s)
  加治屋幹人、小松　奈央，本池　総太, 竹脇　学, 竹下　慶, 應原　一久, 武田　克浩, 岩田　倫幸, 藤田　剛,　栗原英見
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] Clumps of a mesenchymal stem cell/extracellular matrix complex induces periodontal tissue regeneration2017
- Author(s)
  竹脇学、加治屋幹人、武田克浩、佐々木慎也、本池総太、小松奈央、松田真司、應原一久、水野智仁、藤田　剛、栗原英見
- Organizer
  第12回アジア太平洋歯周病学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 絹糸結紮による実験的歯周炎マウスモデルにおける接合上皮の経時的変化について2017
- Author(s)
  竹村　翼，藤田　剛，松田真司，加治屋幹人，内田雄士，芥川桂一，應原一久，武田克浩，水野智仁，栗原英見
- Organizer
  第60回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11389
[Presentation] 歯周炎を誘発した糖尿病モデルマウスに対するGlycyrrhizinの作用について2017
- Author(s)
  芥川桂一, 藤田剛, 竹村翼, 應原一久, 加冶屋幹人, 松田真司, 田利美沙子, 水野智仁,　栗原英見
- Organizer
  日本歯周病学会60周年記念京都大会
- Data Source
  KAKENHI-PROJECT-15K11389
[Presentation] 糖尿病マウスにおいて誘発された歯周炎に対するGlycyrrhizinの抗炎症作用の評価2017
- Author(s)
  芥川桂一, 藤田剛, 竹村翼, 應原一久, 加冶屋幹人, 松田真司, 水野智仁, 栗原英見
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15K11389
[Presentation] ３次元培養される骨髄間葉系幹細胞集塊 Clumps of a MSC/ECM complexにおけるYAP/TAZシグナルの解析2017
- Author(s)
  小松奈央、加治屋　幹人,　本池　総太,　竹脇　学,　竹下　慶,　岩田　倫幸,　應原　一久,　武田　克浩,　藤田　剛,　栗原英見
- Organizer
  第95回国際歯科研究学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] Porphyromonas gulae 感染糖尿病モデルマウスの歯周炎病態の評価2016
- Author(s)
  芥川桂一，藤田剛，内田雄士，竹村翼，應原一久，加冶屋幹人，松田真司，水野智仁，栗原英見
- Organizer
  第 59 回春季日本歯周病学会学術大会
- Place of Presentation
  鹿児島
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15K11389
[Presentation] NR4A1に着目した薬物性歯肉増殖症のメカニズム解明の研究2016
- Author(s)
  岡信　愛、松田真司、加治屋幹人、藤田　剛、栗原英見
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-16K11830
[Presentation] NR4A1を標的とした薬物性歯肉増殖症の新規治療法の開発2016
- Author(s)
  松田　真司、岡信愛、加治屋幹人、藤田　剛、栗原英見
- Organizer
  第32回歯科医学を中心とした総合的な研究を推進する集い
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K11830
[Presentation] 間葉系幹細胞と細胞外基質からなる細胞集塊を用いた新規の他家細胞移植療法の基礎研究2016
- Author(s)
  竹下慶，加治屋幹人, 竹脇学、小松奈央、本池総太、藤田剛、栗原英見
- Organizer
  第59回春季日本歯周病学会学術大会
- Place of Presentation
  鹿児島市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 骨髄間葉系幹細胞集塊Clumps of a MSC/ECM complex (C-MSC)におけるメカノトランスダクションの解析2016
- Author(s)
  小松奈央，加治屋幹人, 竹下慶, 竹脇学, 本池総太, 應原一久, 武田克浩, 岩田倫幸, 藤田剛,栗原英見
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  京都市
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] Elucidation of the role of NR4A1 in drug induced gingival overgrowth2016
- Author(s)
  岡信　愛、松田真司、加治屋幹人、藤田　剛、栗原英見
- Organizer
  第49回広島大学歯学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-16K11830
[Presentation] NR4A1に着目した薬物性歯肉増殖症のメカニズム解明の研究2016
- Author(s)
  岡信　愛、松田真司、加治屋幹人、藤田　剛、栗原英見
- Organizer
  第59回秋季歯周病学会学術大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-16K11830
[Presentation] Clumps of MSCs/ECM complexを用いた新規歯周組織再生療法2016
- Author(s)
  竹脇学, 加治屋幹人, 竹下慶, 小松奈央, 岩田倫幸, 武田克浩, 應原一久, 藤田剛, 栗原英見
- Organizer
  第145回日本歯科保存学会2016年度秋季学術大会
- Place of Presentation
  松本市
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 凍結保存が間葉系幹細胞集塊Clumps of MSCs/ECM complexによる骨再生に及ぼす影響2016
- Author(s)
  本池総太，加治屋幹人, 竹下慶、竹脇学、岩田倫幸、武田克浩、應原一久、藤田剛、栗原英見
- Organizer
  第59回春季日本歯周病学会学術大会
- Place of Presentation
  鹿児島市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] The development of immunomodulatory Clumps of a MSC/ECM complex for novel allograft cell transplantation therapy2015
- Author(s)
  竹下慶、　加治屋　幹人、竹脇　学、小松　奈央、應原　一久、岩田倫幸、藤田　剛、柴　秀樹、栗原　英見
- Organizer
  第58回春季歯周病学会
- Place of Presentation
  幕張メッセ（千葉県千葉市美浜区中瀬）
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-15H05053
[Presentation] 骨髄間葉系幹細胞集塊Clumps of a MSC/ECM complex(C-MSC)を用いた新規組織再生治療法の開発2014
- Author(s)
  加治屋幹人、柴秀樹、竹脇学、竹下慶、Khung Rathvisal、Nguyen Quoc Troung、岩田倫幸、應原一久、武田克浩、藤田剛、栗原英見
- Organizer
  日本歯科医学会　第30回「歯科医学を中心とした総合的な研究を推進する集い」
- Data Source
  KAKENHI-PROJECT-24593122
[Presentation] 骨髄間葉系幹細胞集塊Clumps of mesenchymal stem cells/extracellular matrix complexを利用した新規組織再生療法開発2014
- Author(s)
  加治屋幹人、　橘高瑞穂、　柴秀樹、　竹脇学、　竹下慶、岩田倫幸、應原一久、武田克浩、藤田剛、栗原英見
- Organizer
  第57回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-24593122
[Presentation] 歯肉上皮細胞に着目した歯周炎発症メカニズムの解明とその制御2013
- Author(s)
  藤田　剛
- Organizer
  第56回春季日本歯周病学会学術大会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24593123
[Presentation] ヒト歯肉上皮細胞は TGF-β type I Receptor-smad2-caspase3/9シグナル伝達経路を介してアポトーシスを生じる2013
- Author(s)
  吉本哲也, 藤田剛, 應原一久, 加治屋幹人, 宮川剛史, 今井遙香, 柴秀樹, 栗原英見
- Organizer
  第139回日本歯科保存学会2013年度秋季学術大会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-24593123
[Presentation] TGF-β1が歯肉上皮細胞のアポトーシスシグナル，E-cadherinに与える影響2013
- Author(s)
  吉本哲也, 藤田剛, 應原一久, 加治屋幹人, 宮川剛史, 今井遙香, 柴秀樹, 栗原英見
- Organizer
  第56回春季日本歯周病学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24593123
[Presentation] Aggregatibacter actynomycetemcomitansのouter membrane protein-29はヒト歯肉上皮細胞においてsmad2を介してアポトーシスシグナルを誘導し，E-cadherinの発現を減少させる2012
- Author(s)
  吉本哲也，藤田　剛，應原一久，内田雄士，松田真司，宮川剛史，今井遥香，柴　秀樹，河口浩之，栗原英見
- Organizer
  平成24年度春季学術大会（第136回）
- Place of Presentation
  沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24593123
[Presentation] 抗菌ペプチドLL37はラット頭蓋骨骨欠損モデルにおける骨再生を促進する2012
- Author(s)
  橘髙瑞穂, 藤田　剛, 柴　秀樹, 栗原英見
- Organizer
  第54回歯科基礎医学会学術大会ならび総会
- Place of Presentation
  郡山市
- Data Source
  KAKENHI-PROJECT-24593122
[Presentation] イルソグラジンマレイン酸を用いた歯肉上皮細胞の機能制御による歯周病予防法開発に対する基礎的研究2011
- Author(s)
  藤田剛
- Organizer
  第53回歯科基礎医学会,歯科基礎医学会学会賞受賞講演
- Place of Presentation
  長良川国際会議場(岐阜)(招待講演)
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-22792087
[Presentation] イルソグラジンマレイン酸を用いた歯肉上皮細胞の機能制御による歯周病予防法開発に関する研究2011
- Author(s)
  藤田剛
- Organizer
  第53回歯科基礎医学会,歯科基礎医学会学会賞受賞講演(招待講演)
- Place of Presentation
  長良川国際会議場(岐阜)
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-22792087
[Presentation] Irsogladine maleate regulates gingival epithelial barrier function in inflammatory condition.2011
- Author(s)
  藤田剛
- Organizer
  International Association for Dental Research
- Place of Presentation
  サンディエゴコンベンションセンター,USA
- Year and Date
  2011-03-17
- Data Source
  KAKENHI-PROJECT-22792087
[Presentation] マレイン酸イルソグジンはAggregatibacter qctiomycetemcomitans.による歯肉上皮のケモカイン産生及びE-cadherin発低下を制御する2009
- Author(s)
  藤田剛
- Organizer
  日本歯周病学会秋季学術大会
- Place of Presentation
  宮崎観光ホテル(宮崎)
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-20791613
[Presentation] マレイン酸イルソグラジンはAggregatibacter qctinomycetemcomitans. による歯肉上皮のケモカイン産生及びE-cadherin発低下を制御する2009
- Author(s)
  藤田剛
- Organizer
  日本歯周病学会秋季学術大会
- Place of Presentation
  宮崎観光ホテル(宮崎)
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-20791613
[Presentation] マレイン酸イルソグラジンはAggregatibacter actinomycetemcomitansによって惹起される歯肉上皮組織への炎症細胞浸潤を抑制する2008
- Author(s)
  藤田剛
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  TOC有明コンベンションホール(東京)
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-20791613
[Presentation] 抗菌ペプチドLL37はヒト歯髄細胞のmigrationを促進する2008
- Author(s)
  加治屋幹人、柴秀樹、藤田剛、武田克浩、内田雄士、水野智仁、河口浩之、栗原英見
- Organizer
  平成20年度(第129回)日本歯科保存学会秋季大会
- Place of Presentation
  富山
- Year and Date
  2008-11-06
- Data Source
  KAKENHI-PROJECT-20592430
[Presentation] IL・1β刺激による歯肉上皮細胞の細胞間コミュニケーションの変化とマレイン酸イルソグラジンの影響2007
- Author(s)
  藤田剛
- Organizer
  日本歯周病学会
- Place of Presentation
  東京
- Year and Date
  2007-09-22
- Data Source
  KAKENHI-PROJECT-18791595
[Presentation] TGF-beta1 induces mitochondria-dependent apoptosis in human gingival epithelial cells.
- Author(s)
  Yoshimoto T., Fujita T., Kajiya　M., Shiba　H., Kurihara　H.
- Organizer
  92nd General Session & Exhibition of the International Association of Dental Research
- Place of Presentation
  Capetown/Republic ｏｆ　South Africa
- Year and Date
  2014-06-25 – 2014-06-28
- Data Source
  KAKENHI-PROJECT-25670885
[Presentation] ヒト歯肉上皮細胞におけるバクテリアによるアポトーシスとsmad2との関与
- Author(s)
  吉本哲也，藤田剛，柴秀樹，栗原英見
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24593123

1. KURIHARA HIDEMI (40161765)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
2. SHIBA Hideki (60260668)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
3. 加治屋幹人 (00633041)

# of Collaborated Projects: 5 results

# of Collaborated Products: 20 results
4. MATSUDA Shinji (30611321)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
5. MIZUNO Noriyoshi (60325181)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
6. TAKEDA Katsuhiro (10452591)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
7. UCHIDA Yuushi (40363080)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. FUJIOKA Daisuke (20379879)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. Ouhara Kazuhisa (80550425)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
10. 河口浩之 (10224750)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 岩田倫幸 (30418793)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
12. YOSHINO Hiroshi (50240338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Miyauchi Mutsumi (50169265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 加藤功一 (50283875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 占部智 (10403536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 古庄寿子 (00634461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小澤龍彦 (10432105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 杉山英二 (70179167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. 池谷真 (20442923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 菊池毅 (40421242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 三谷章雄 (50329611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 長谷川義明 (70460524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 後藤久嗣 (10783037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. MIYAGAWA TSUYOSHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. IMAI HARUKA

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. YOSHIMOTO TETSUYA

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
27. AKUTAGAWA KEIICHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
28. TAKEMURA TASUKU

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
29. ISHIHARA kazuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KUDO yoshiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. MORINO Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. Komatsu Nao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. HIRATA Shintaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 松田由喜子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujita Tsuyoshi 藤田 剛

藤田 剛 フジタ ツヨシ

FUJITA Tsuyoshi 藤田 剛

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Regulation of gingival epithelial cell's function suppresses systemic infection of periodontal pathogen.Principal Investigator

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The regulatory mechanism of function on gingival epithelium by irsogladine maleatePrincipal Investigator

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Investigation of preventive method for periodontal disease by regulating gingival epithelial cell' s functionPrincipal Investigator

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Fujita Tsuyoshi 藤田剛

藤田剛フジタツヨシ

FUJITA Tsuyoshi 藤田剛