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tanaka taku  田中 卓

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TANAKA Taku  田中 卓

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Researcher Number 80425686
Other IDs
Affiliation (Current) 2025: 公益財団法人東京都医学総合研究所, 先端基礎医科学研究分野, 主席研究員
Affiliation (based on the past Project Information) *help 2020 – 2023: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主席研究員
2012 – 2014: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 主席研究員
2011: (財)東京都医学総合研究所, ゲノム医科学研究分野, 主任研究員
2011: (財)東京都医学総合研究所, ゲノム医科学研究分野, 主席研究員
2010: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 … More
2009: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
2008: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 研究員
2008: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員
2007: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 45010:Genetics-related / Functional biochemistry / Molecular biology
Except Principal Investigator
Structural biochemistry / Molecular biology / Functional biochemistry
Keywords
Principal Investigator
DNA複製 / RecA / PriA / DNA replication / transcription / G4 / SDR / 転写 / マイクロアレイ / 分子間相互作用 … More / 複製再開始 / グアニン四重鎖 / RNA-DNAハイブリッド / RNaseHI / RNA-DNA hybrid / G-quadruplex / RNase H / R-loop / replication origin / multi-replicon / 修復・組換え / DNA結合 / フォーク安定化因子 / 複製フォーク / 複製起点 / 複製 / 大腸菌 / 結晶構造解析 / 核酸 / タンパク質 / 分子認識 / ・複製フォーク … More
Except Principal Investigator
DNA複製停止 / 染色体脆弱部位 / 複製フォーク / ゲノム不安定性 / 複製複合体 / 染色体不安定性症候群 / DNA結合タンパク質 / チェックポイント応答 / RecGタンパク質 / 複製ストレス / PriAタンパク質 / 構造解析 / 染色体ダイナミクス / リン酸化 / 複製起点 / 染色体DNA複製 / 脳発生 / 細胞分裂 / 乗り越えDNA合成 / 複製タイミング / 減数分裂期組換え / チェックポイント / Cdc7キナーゼ / 染色体DNA複製開始 / DNAヘリカーゼ / ChIP-chip解析 / aphidicolin / 染色体免疫沈降 / PriAタンパク Less
  • Research Projects

    (7 results)
  • Research Products

    (43 results)
  • Co-Researchers

    (13 People)
  •  転写依存性DNA複製開始制御機構におけるグアニン四重鎖(G4)形成の役割Principal Investigator

    • Principal Investigator
      田中 卓
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 45010:Genetics-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  The regulation of initiation for chromosomal DNA replication by formation of G4 structurePrincipal Investigator

    • Principal Investigator
      TANAKA Taku
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 45010:Genetics-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Studies on the functions and structures of Cdc7 kinase, essential for initiation of DNA replication

    • Principal Investigator
      MASAI Hisao
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Molecular mechanism for arrested fork stabilization by fork recognition complexPrincipal Investigator

    • Principal Investigator
      TANAKA Taku
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Stabilization of stalled replication forks by fork-binding proteins

    • Principal Investigator
      MASAI Hisao
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Structural biochemistry
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  停止複製フォーク結合タンパク質PriAを用いた染色体脆弱部位の探索

    • Principal Investigator
      MASAI Hisao
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Identification and structure-function analyses of recognition/processing factors for arrested replication forksPrincipal Investigator

    • Principal Investigator
      TANAKA Taku
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research

All 2023 2022 2021 2020 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

  • [Book] 「分子間相互作用解析ハンドブック」(礒辺俊明,中山敬一,伊藤隆司/編) 第二章 タンパク質-核酸相互作用解析法 1.South-Western法2007

    • Author(s)
      田中 卓、正井 久雄
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Journal Article] Stalled replication forks : Making ends meet for recognition and stabilization.2010

    • Author(s)
      Masai, H., Tanaka, T., Kohda, D.
    • Journal Title

      BioEssays

      Volume: 32 Pages: 687-697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21657036
  • [Journal Article] Stalled replication forks : Making ends meet for recognition and stabilization2010

    • Author(s)
      Masai, H., Tanaka, T., Kohda, D.
    • Journal Title

      BioEssays (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21657036
  • [Journal Article] Bacterial replication fork2010

    • Author(s)
      Tanaka, T., Masai, H.
    • Journal Title

      Encyclopedia of Life Sciences (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21657036
  • [Journal Article] Bacterial replication fork.2010

    • Author(s)
      Tanaka, T., Masai, H.
    • Journal Title

      Encyclopedia of Life Sciences

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21657036
  • [Journal Article] Bacterial primosome.2010

    • Author(s)
      Tanaka, T., Masai, H.
    • Journal Title

      Encyclopedia of Life Sciences

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21657036
  • [Journal Article] Bacterial primosome2010

    • Author(s)
      Tanaka, T., Masai, H.
    • Journal Title

      Encyclopedia of Life Sciences (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21657036
  • [Journal Article] Fission yeast Swil-Swi3 complex facilitates DNA binding of Mrc1.2010

    • Author(s)
      Tanaka, T., Yokoyama, M., Matsumoto, S., Fukatsu, R., You, Z., Masai, H.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 39609-39622

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21657036
  • [Journal Article] Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts2009

    • Author(s)
      Tanaka, H., Kubota, Y., Tsujimura, T., Kumano, M., Masai, H., Takisawa, H.
    • Journal Title

      Genes to Cells 14

      Pages: 949-963

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21657036
  • [Journal Article] Escherichia coli PriA protein, two modes of DNA binding and activation of ATP hydrolysis2007

    • Author(s)
      Tanaka, T., Mizukoshi, T., Sasaki, K., Kohda, D., and Masai, H
    • Journal Title

      J. Biol. Chem 282

      Pages: 19917-19927

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Journal Article] Escherishia PriA protein, two modes of DNA binding and activation of ATP hydrolysis2007

    • Author(s)
      Tanaka, T., Mizukohsi, T., Sasaki, K., Kohda, D., and Masai, H.
    • Journal Title

      Journal of Biological Chemistry 282

      Pages: 19917-19927

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Journal Article] Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA2007

    • Author(s)
      Sasaki, K., Ose, T., Okamoto, N., Maenaka, K., Tanaka, T., Masai, H., Saito, M., Shirai, T., and Kohda, D.
    • Journal Title

      EMBO J 28

      Pages: 2584-2593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Journal Article] Strustural basis the 3'-end recognition of a leading strand in stall replication forks by PriA2007

    • Author(s)
      Sasaki, K., Ose T., Okamoto n., Maenaka K., Tanaka T., Masai H ., Saito M., Shirai T., and Kohda D.
    • Journal Title

      EMBO Journal 26

      Pages: 2589-2593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] The transcription-driven multi-replicon mode of the Escherichia coli chromosomal replication and roles of G4 structure.2023

    • Author(s)
      田中 卓、鷺 朋子、深津 理乃、覺正 直子、正井 久雄
    • Organizer
      第46回日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K05872
  • [Presentation] multi-replicon 様式の大腸菌染色体複製は転写に伴うG4形成に依存する2022

    • Author(s)
      田中 卓、鷺 朋子、深津 理乃、正井 久雄
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K06762
  • [Presentation] multi-replicon 様式の大腸菌染色体複製機構 : RNA-DNA hybrid/G4 構造の関与2021

    • Author(s)
      田中 卓、鷺 朋子、深津 理乃、西藤 泰昌、正井 久雄
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K06762
  • [Presentation] multi-replicon 様式の大腸菌染色体複製メカニズム2020

    • Author(s)
      田中 卓、鷺 朋子、西藤 泰昌、正井 久雄
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K06762
  • [Presentation] "染色体DNA複製プログラムの制御機構と起源・進化"2014

    • Author(s)
      正井 久雄、田中 卓、加納 豊、山崎 聡志、松本 清治、吉沢 直子、松嶋 夢叶
    • Organizer
      The 2nd Symposium of Cell Cycle Control and Cell Fate (第2回 細胞周期制御と細胞運命 シンポジウム)
    • Place of Presentation
      浜松
    • Invited
    • Data Source
      KAKENHI-PROJECT-23657081
  • [Presentation] 染色体DNA 複製プログラムの制御機構と起源・進化2014

    • Author(s)
      正井 久雄, 田中 卓, 加納 豊, 山崎 聡志, 松本 清治, 吉沢 直子, 松嶋 夢叶
    • Organizer
      The 2nd Symposium of Cell Cycle Control and Cell Fate (第2回 細胞周期制御と細胞運命シンポジウム)
    • Place of Presentation
      浜松
    • Invited
    • Data Source
      KAKENHI-PROJECT-23657081
  • [Presentation] PriA binds to oriC segments upon induction of fork stall in Escherichia coli cells2013

    • Author(s)
      Tanaka, T. and Masai, H.
    • Organizer
      第36回日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2013-12-04
    • Data Source
      KAKENHI-PROJECT-23570183
  • [Presentation] Toward the elucidation of molecular basis of kinase activation and substrate recognition of Cdc7-Dbf4 kinase complex : use of Microsporidia as a model2012

    • Author(s)
      Iwasaki, R., Tanaka, T. Shimada, A., Kohda, D., and Masai, H.
    • Organizer
      第35回日本分子生物学会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-12
    • Data Source
      KAKENHI-PROJECT-23570183
  • [Presentation] Detection of chromosomal fragile sites: application of specific PriA binding to arrested replication forks in living cells.2011

    • Author(s)
      田中 卓、正井 久雄
    • Organizer
      第34回日本分子生物学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23570183
  • [Presentation] Detection of chromosomal fragile sites : application of specific PriA binding to arrested replication forks in living cells2011

    • Author(s)
      Tanaka, T. and Masai, H.
    • Organizer
      第34回日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-23570183
  • [Presentation] Actions of Mcm helicase and fork stabilizing factors at replication forks2009

    • Author(s)
      Masai, H., You, Z., Tanaka, T., Yokoyama, M.
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21657036
  • [Presentation] Regulation of replication fork integrity during S phase2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Mika Yokoyama, Michie Shimmoto, Naoko Kakusho, Naoko Yoshizawa-Sugata and Taku Tanaka
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸(招待講演)
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] Regulation of assembly and progression of replication fork by Cdc7 kinase.2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Mika Yokoyama, Michie Shimmoto, Naoko Kakusho, and Taku Tanaka.
    • Organizer
      The First GCEO Symposium at Tokyo Institute of Technology on Chromosome Biology
    • Place of Presentation
      東京
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] Regulation of establishment and maintenance of replication fork by Cdc7 kinase.2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Naoko Kakusho, Mchie Shimmoto, Mika Yokoyama, Yutaka Kanoh, Taku Tanaka and Yiikari Odagiri.
    • Organizer
      Ataxia-Telangiectasia Workshop
    • Place of Presentation
      滋賀県大津市
    • Year and Date
      2008-04-25
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] Regulation of replication fork integrity during S phase.2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsranoto, Yutaka Kanoh, Mika Yokoyama, Michie Shimmoto, Naoko Kakusho, Naoko Yoshizawa-Sugata and Taku Tanaka.
    • Organizer
      第31回 日本分子生物学会
    • Place of Presentation
      兵庫県神戸市
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] Regulation of establishment and maintenance of replication fork by Cdc7 kinase2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Naoko Kakusho, Michie Shimmoto, Mika Yokoyama, Yutaka Kanoh, Taku Tanaka and Yukari Odagiri
    • Organizer
      Ataxia-Telangiectasia Workshop 2008
    • Place of Presentation
      滋賀(招待講演)
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] Regulation of establishment and maintenance of replication fork by Cdc7 kinase2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Naoko Kakusho, Mika Yokoyama, Yutaka Kanoh, Michie Simmoto and Taku Tanaka
    • Organizer
      EMBO Conference on "Replication and Segregation of Chromosomes"
    • Place of Presentation
      ノルウェイ(招待講演)
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] Regulation of replication fork in maintenance of genomic integrity.2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Michie Shimmoto, Mika Yokoyama, Taku Tanaka, Naoko Kakusho, Naoko Yoshizawa-Sugata, Zhiying You, Sayuri Ito, Chika Taniyama and Ai Ishii.
    • Organizer
      第6回 3R Symposium
    • Place of Presentation
      静岡県掛川市
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] Regulation of replication fork in maintenance of genomic integrity2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Michie Shimmoto, Mika Yokoyama, Taku Tanaka, Naoko Kakusho, Naoko Yoshizawa-Sugata, Zhiying You, Sayuri Ito, Chika Taniyama and Ai Ishii
    • Organizer
      第6回3R Symposium
    • Place of Presentation
      静岡(招待講演)
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] Regulation of assembly and progression of replication fork by Cdc7 kinase2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Mika Yokoyama, Michie Shimmoto, Naoko Kakusho, and Taku Tanaka
    • Organizer
      The First GCEO Symposium at Tokyo Institute of Technology on Chromosome Biology 2008
    • Place of Presentation
      東京(招待講演)
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] 分裂酵母Mrc1タンパクの精製とその性情の解析2008

    • Author(s)
      横山 美佳、田中 卓、覺正 直子、正井 久雄
    • Organizer
      第25回染色体ワークショップ
    • Place of Presentation
      ポスター発表
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] Regulation of establishment and maintenance of replication fork by Cdc7 kinase.2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Naoko Kakusho, Mika Yokoyama, Yutaka Kanoh, Michie Simmoto and Taku Tanaka.
    • Organizer
      EMBO Conference on "Replication and Segregation of Chromosomes"
    • Place of Presentation
      Norway, Geilo
    • Year and Date
      2008-06-19
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] 、分裂酵母Mrc1タンパクの精製とその性情の解析2007

    • Author(s)
      横山 美佳、田中 卓、覺正 直子、正井 久雄
    • Organizer
      第30回日本分子生物学会
    • Place of Presentation
      横浜(ポスター発表)
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] PriAタンパク質:停止複製フォーク特異的認識のための構造基盤2007

    • Author(s)
      田中 卓、佐々木 香織、水越 利巳、神田 大輔、正井 久雄
    • Organizer
      第30回日本分子生物学会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] DNA結合ドメインの2つのモジュールの役割とDNA3'末端結合ポケットの特異な構造2007

    • Author(s)
      田中 卓、佐々木 香織、神田 大輔、正井 久雄
    • Organizer
      第4回21世紀大腸菌研究会
    • Place of Presentation
      静岡県藤枝市
    • Year and Date
      2007-07-18
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] PriAタンパク質:停止複製フォーク特異的認識のための構造基盤2007

    • Author(s)
      田中 卓、佐々木 香織、水越 利巳、神田 大輔、正井 久雄
    • Organizer
      第30回日本分子生物学会
    • Place of Presentation
      横浜(口頭およびポスター発表)
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] Structural basis for the DNA recognition of PriA protein in the stalled DNA replication fork2007

    • Author(s)
      佐々木 香織、田中 卓、正井 久雄、前仲 勝実、神田 大輔
    • Organizer
      第30回日本分子生物学会
    • Place of Presentation
      横浜(ポスター発表)
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] PriAタンパク質による停止複製フォーク認識:DNA結合ドメインの2つのモジュールの役割とDNA3'末端結合ポケットの特異な構造2007

    • Author(s)
      田中 卓、佐々木 香織、神田 大輔、正井 久雄
    • Organizer
      第4回21世紀大腸菌研究会
    • Place of Presentation
      静岡(口頭発表)
    • Data Source
      KAKENHI-PROJECT-19770157
  • [Presentation] 染色体DNA複製プログラムの制御機構と起源・進化

    • Author(s)
      正井 久雄、田中 卓、加納 豊、山崎 聡志、松本 清治、吉沢 直子、松嶋 夢叶
    • Organizer
      第2回 細胞周期制御と細胞運命 シンポジウム
    • Place of Presentation
      浜松(静岡)
    • Year and Date
      2014-02-13 – 2014-02-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247031
  • [Presentation] PriA binds to oriC segments upon induction of fork stall in Escherichia coli cells

    • Author(s)
      田中 卓、正井 久雄
    • Organizer
      第36回日本分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23570183
  • 1.  KANO Yutaka (90450593)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 2.  MASAI Hisao (40229349)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 12 results
  • 3.  MATSUMOTO Seiji (40190532)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  KAKUSHO Naoko (30599593)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YOSHIZAWA Naoko (30344071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TAKAI Yuko (90332270)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  MORIYAMA Kenji (00250217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SHINMOTO Michie (20216237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ODA Masako (50399474)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ITO Sayuri (60462777)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  MIYATAKE Shoichiro (30239420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  HAYANO Motoshi (30593644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  須賀田 直子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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