kamikubo yuuji 上窪裕二

… Alternative Names

KAMIKUBO Yuji 上窪裕二

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Researcher Number	80509670
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 順天堂大学, 医学部, 准教授 2009 – 2018: Juntendo University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Pain science / Basic Section 51030:Pathophysiologic neuroscience-related / Neuroscience in general / Neuroscience in general Except Principal Investigator Basic Section 46010:Neuroscience-general-related / Neurophysiology / General neuroscience / Neuroscience in general / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology
Keywords	Principal Investigator Gタンパク質共役型受容体 / 代謝型グルタミン酸受容体 / GPCR / シナプス / 膜タンパク質 / ライブセル・イメージング / FRET / シナプス可塑性 / アデノシン受容体 / ライブセルイメージング … More / GABAB受容体 / GABA / 痛み / 疼痛 / 小脳 / 長期抑圧 / シナプス伝達 / 神経変性疾患 / シグナル伝達 / 超複合体 / 海馬 / 神経伝達 / アミロイド / 器官培養 / 老人斑 / GABA受容体 / アミロイドβ / アルツハイマー病 / 受容体 / かゆみ / 脳神経疾患 / 神経科学 / 蛍光蛋白質再構成 / 掻痒 / 痒み / 脊髄 / 感覚伝達 / 神経細胞 / 運動学習 / 小脳長期抑圧 / G タンパク質共役型受容体 / GABA_B受容体 / アデノシンA1受容体 / mGluR1 / シグナル・クロストーク / 細胞神経科学 / 分子 … More Except Principal Investigator ニューロン / シナプス可塑性 / アデノシン / Gタンパク質共役型受容体 / ガンマ・アミノ酪酸 / Gタンパク質 / 小脳 / 学習 / 受容体 / 脳神経疾患 / 脂質 / 痴呆 / GPCR / 伝達物質 / 脳 / 記憶 / 中枢神経系 / 運動 / 可塑性 / シナプス / 表面プラズモン共鳴 / 蛍光カルシウム・イメージング / Cキナーゼ / グルタミン酸 / Gタンパク質共役型受受容体 / 神経科学 / 生理学 / Ｇタンパク質 / アルツハイマー病 / 認知症 / 神経変性疾患 Less

GPCR超複合体機能の定量的網羅的解析Principal Investigator
- Principal Investigator
  
  上窪裕二
- Project Period (FY)
  2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Juntendo University
Manipulation of membrane protein supercomplexes to elucidate their molecular dynamics and functionPrincipal Investigator
- Principal Investigator
  
  上窪裕二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Juntendo University
GPCR-Amyloid precursor protein supercomplex regulate neural functionPrincipal Investigator
- Principal Investigator
  
  Kamikubo Yuji
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Juntendo University
Analysis of the regulatory mechanism of motor learning using real-time FRET and fast-scan voltammetry
- Principal Investigator
  
  Tabata Toshihide
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  University of Toyama
Inter-GPCR interplay regulate intractable itch.Principal Investigator
- Principal Investigator
  
  Kamikubo Yuji
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Juntendo University
Regulation of pain through inter-GPCR interplayPrincipal Investigator
- Principal Investigator
  
  Kamikubo Yuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Juntendo University
Regulation of synaptic plasticity via hetero-GPCR modulation: an analysis using surface plasmon resonance imaging
- Principal Investigator
  
  Tabata Toshihide
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  University of Toyama
Microdomain-dependent acceleration mechanisms for amyloidogenic processing of amyloid precursor protein induced by endocytic membrane traffic impairment
- Principal Investigator
  
  SAKURAI Takashi
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Juntendo University
Influence of ambient neuromodulators on learning through hetero-GPCR interplay
- Principal Investigator
  
  TABATA Toshihide
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  University of Toyama
Adenosine A1 receptor interacts with mGluR1 and regulates motor learningPrincipal Investigator
- Principal Investigator
  
  KAMIKUBO Yuji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Juntendo University
Regulation of synaptic plasticity through inter-GPCR interplayPrincipal Investigator
- Principal Investigator
  
  KAMIKUBO Yuji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Juntendo University
A novel microdomain-dependent regulatory mechanism of amyloid precursor protein processing
- Principal Investigator
  
  SAKURAI Takashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Juntendo University

[Book] エース薬理学2020
- Author(s)
  上窪裕二, 櫻井隆(担当:分担執筆, 範囲:生体内情報伝達の基礎)
- Total Pages
  303
- Publisher
  南山堂
- ISBN
  9784525140717
- Data Source
  KAKENHI-PROJECT-17K09040
[Book] Co-immunoprecipitation Analysis of GPCR Complexes in the Central Nervous System. In: Odagaki Y., Borroto-Escuela D. (eds) Co-Immunoprecipitation Methods for Brain Tissue. Neuromethods, vol 144.2019
- Author(s)
  Kamikubo Y., Sakurai T.
- Total Pages
  5
- Publisher
  Humana Press, New York, NY
- Data Source
  KAKENHI-PROJECT-17K09040
[Journal Article] Nuclear SphK2/S1P signaling is a key regulator of ApoE production and Aβ uptake in astrocytes2024
- Author(s)
  Komai Masato、Noda Yuka、Ikeda Atsuya、Kaneshiro Nanaka、Kamikubo Yuji、Sakurai Takashi、Uehara Takashi、Takasugi Nobumasa
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 65 Issue: 3 Pages: 100510-100510
- DOI
  10.1016/j.jlr.2024.100510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06170, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-23KJ1603, KAKENHI-PROJECT-21H02815
[Journal Article] The Pursuit of the “Inside” of the Amyloid Hypothesis?Is C99 a Promising Therapeutic Target for Alzheimer’s Disease?2023
- Author(s)
  Takasugi Nobumasa、Komai Masato、Kaneshiro Nanaka、Ikeda Atsuya、Kamikubo Yuji、Uehara Takashi
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 3 Pages: 454-454
- DOI
  10.3390/cells12030454
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-20K07014
[Journal Article] Ex vivo analysis platforms for monitoring amyloid precursor protein cleavage2023
- Author(s)
  Kamikubo Yuji、Jin Hao、Zhou Yiyao、Niisato Kazue、Hashimoto Yoshie、Takasugi Nobumasa、Sakurai Takashi
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 15 Pages: 1068990-1068990
- DOI
  10.3389/fnmol.2022.1068990
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02815, KAKENHI-PROJECT-20K07014, KAKENHI-PROJECT-23K06170, KAKENHI-PROJECT-20K07765
[Journal Article] Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle2023
- Author(s)
  Okamoto Kazuki、Kamikubo Yuji、Yamauchi Kenta、Okamoto Shinichiro、Takahashi Megumu、Ishida Yoko、Koike Masato、Ikegaya Yuji、Sakurai Takashi、Hioki Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 323-323
- DOI
  10.1038/s41598-022-27372-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15230, KAKENHI-PROJECT-21H02815, KAKENHI-PROJECT-22KJ1876, KAKENHI-PROJECT-20K07231, KAKENHI-PROJECT-23K21351, KAKENHI-PROJECT-20K07765
[Journal Article] Multifaceted analysis of nanotoxicity using primary cultured neurons2022
- Author(s)
  Kamikubo Yuji、Yamana Tomohito、Inoue Yuriko、Sakurai Takashi
- Journal Title
  
  Nano Express
  
  Volume: 3 Issue: 3 Pages: 035003-035003
- DOI
  10.1088/2632-959x/ac7cfd
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10835, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-22K10664
[Journal Article] Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer’s disease2022
- Author(s)
  Kaneshiro Nanaka、Komai Masato、Imaoka Ryosuke、Ikeda Atsuya、Kamikubo Yuji、Saito Takashi、Saido Takaomi C.、Tomita Taisuke、Hashimoto Tadafumi、Iwatsubo Takeshi、Sakurai Takashi、Uehara Takashi、Takasugi Nobumasa
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 3 Pages: 103869-103869
- DOI
  10.1016/j.isci.2022.103869
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-21H02815, KAKENHI-PROJECT-19J22442, KAKENHI-PROJECT-20K07014, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-21K07270
[Journal Article] Peripheral endomorphins drive mechanical alloknesis under the enzymatic control of CD26/DPPIV2022
- Author(s)
  Komiya Eriko、Tominaga Mitsutoshi、Hatano Ryo、Kamikubo Yuji、Toyama Sumika、Sakairi Hakushun、Honda Kotaro、Itoh Takumi、Kamata Yayoi、Tsurumachi Munehiro、Kishi Ryoma、Ohnuma Kei、Sakurai Takashi、Morimoto Chikao、Takamori Kenji
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 149 Issue: 3 Pages: 1085-1096
- DOI
  10.1016/j.jaci.2021.08.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-19K08756, KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-20K08680, KAKENHI-PROJECT-21K16307, KAKENHI-PROJECT-20K22745, KAKENHI-PROJECT-23K20320, KAKENHI-PROJECT-23K24217
[Journal Article] 異種G蛋白質共役型受容体相互作用による代謝型グルタミン酸受容体の制御2021
- Author(s)
  上窪裕二, 田端俊英, 坂入伯駿, 櫻井隆
- Journal Title
  
  脳神経内科
  
  Volume: 94 Pages: 468-475
- Data Source
  KAKENHI-PROJECT-17K09040
[Journal Article] Midbrain as an Ex Vivo Analysis Platform for Parkinson’s Disease2021
- Author(s)
  Kamikubo Yuji, Wakisaka Keiko, Imai Yuzuru, Sakurai Takashi
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2322 Pages: 111-117
- DOI
  10.1007/978-1-0716-1495-2_11
- ISBN
  9781071614945, 9781071614952
- Data Source
  KAKENHI-PROJECT-20K07765
[Journal Article] 異種G蛋白質共役型受容体相互作用による代謝型グルタミン酸受容体の制御2021
- Author(s)
  上窪裕二, 田端俊英, 坂入伯駿, 櫻井隆
- Journal Title
  
  脳神経内科
  
  Volume: 94 Pages: 468-475
- Data Source
  KAKENHI-PROJECT-20K07765
[Journal Article] Inhibition of endothelin A receptor by a novel, selective receptor antagonist enhances morphine-induced analgesia: Possible functional interaction of dimerized endothelin A and μ-opioid receptors. Biomed Pharmacother.2021
- Author(s)
  Kuroda Y, Nonaka M, Kamikubo Y, Ogawa H, Murayama T, Kurebayashi N, Sakairi H, Miyano K, Komatsu A, Dodo T, Nakano-Ito K, Yamaguchi K, Sakurai T, Iseki M, Hayashida M, Uezono Y
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 141 Pages: 111800-111800
- DOI
  10.1016/j.biopha.2021.111800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08866, KAKENHI-PROJECT-19K16497, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-21K06584, KAKENHI-PROJECT-20K22745, KAKENHI-PROJECT-19H03404
[Journal Article] 異種G蛋白質共役型受容体相互作用による代謝型グルタミン酸受容体の制御2020
- Author(s)
  上窪裕二，田端俊英，坂入伯駿，櫻井隆
- Journal Title
  
  脳神経内科
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-18K06461
[Journal Article] 分子から迫る神経薬理学：GABAB受容体の生理的機能2019
- Author(s)
  田端俊英、上窪裕二、坂入伯駿
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 37 Pages: 630-631
- Data Source
  KAKENHI-PROJECT-18K06461
[Journal Article] 分子から迫る神経薬理学：GABAB受容体の種類と構造2019
- Author(s)
  上窪裕二、坂入伯駿、田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 37 Pages: 504-505
- Data Source
  KAKENHI-PROJECT-18K06461
[Journal Article] Cerebellar Neurodegeneration and Neuronal Circuit Remodeling in Golgi pH Regulator-Deficient Mice2019
- Author(s)
  Sou Yu-shin、Kakuta Soichiro、Kamikubo Yuji、Niisato Kazue、Sakurai Takashi、Parajuli Laxmi Kumar、Tanida Isei、Saito Hiromitsu、Suzuki Noboru、Sakimura Kenji、Maeda Yusuke、Kinoshita Taroh、Uchiyama Yasuo、Koike Masato
- Journal Title
  
  eNeuro
  
  Volume: 6 Issue: 3 Pages: 0427-18
- DOI
  10.1523/eneuro.0427-18.2019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09040, KAKENHI-PROJECT-19K07276, KAKENHI-PROJECT-18K14842, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-17K15550, KAKENHI-PLANNED-17H06422
[Journal Article] 分子から迫る神経薬理学：GABAB受容体の薬理と臨床応用2019
- Author(s)
  坂入伯駿、上窪裕二、田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 37 Pages: 760-761
- Data Source
  KAKENHI-PROJECT-18K06461
[Journal Article] TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes2018
- Author(s)
  Takasugi Nobumasa、Araya Runa、Kamikubo Yuji、Kaneshiro Nanaka、Imaoka Ryosuke、Jin Hao、Kashiyama Taku、Hashimoto Yoshie、Kurosawa Masaru、Uehara Takashi、Nukina Nobuyuki、Sakurai Takashi
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 8 Pages: 0200988-0200988
- DOI
  10.1371/journal.pone.0200988
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08272, KAKENHI-PROJECT-17K09040, KAKENHI-PROJECT-17H01564, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-18H00446
[Journal Article] Induction of Oxidative Stress and Cell Death in Neural Cells by Silica Nanoparticles2018
- Author(s)
  Kamikubo Yuji、Yamana Tomohito、Hashimoto Yoshie、Sakurai Takashi
- Journal Title
  
  ACS Chemical Neuroscience
  
  Volume: 10 Issue: 1 Pages: 304-312
- DOI
  10.1021/acschemneuro.8b00248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09040, KAKENHI-PROJECT-16H04667
[Journal Article] アデノシン受容体の神経系における機能と役割2017
- Author(s)
  田端俊英、上窪裕二
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 35 Pages: 10-11
- Data Source
  KAKENHI-PROJECT-26430012
[Journal Article] Consecutive Analysis of BACE1 Function on Developing and Developed Neuronal Cells2017
- Author(s)
  Kamikubo Y, Takasugi N, Niisato K, Hashimoto Y, Sakurai T
- Journal Title
  
  J Alzheimers Diｓ
  
  Volume: 56 Issue: 2 Pages: 641-653
- DOI
  10.3233/jad-160806
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-26430059, KAKENHI-PROJECT-26460707, KAKENHI-PROJECT-17K09040
[Journal Article] アデノシン受容体をターゲットとした臨床応用と最新研究2017
- Author(s)
  上窪裕二、田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 35 Pages: 128-129
- Data Source
  KAKENHI-PROJECT-26460707
[Journal Article] L-DOPA sensitizes vasomotor tone by modulating the vascular alpha1-adrenergic receptor2017
- Author(s)
  Masukawa Daiki、Koga Motokazu、Sezaki Anna、Nakao Yuka、Kamikubo Yuji、Hashimoto Tatsuo、Okuyama-Oki Yuki、Aladeokin Aderemi Caleb、Nakamura Fumio、Yokoyama Utako、Wakui Hiromichi、Ichinose Hiroshi、Sakurai Takashi、Umemura Satoshi、Tamura Koichi、Ishikawa Yoshihiro、Goshima Yoshio
- Journal Title
  
  JCI Insight
  
  Volume: 2 Issue: 18 Pages: 1-16
- DOI
  10.1172/jci.insight.90903
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07062, KAKENHI-PROJECT-17K09040, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H04687, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K21273, KAKENHI-PROJECT-15H05761, KAKENHI-PUBLICLY-17H05555, KAKENHI-PROJECT-16H05300
[Journal Article] アデノシン受容体の神経系における機能と役割2017
- Author(s)
  田端俊英、上窪裕二
- Journal Title
  
  Clinical neuroscience
  
  Volume: 35 Pages: 10-11
- Data Source
  KAKENHI-PROJECT-26460707
[Journal Article] アデノシン受容体をターゲットとした臨床応用と最新研究2017
- Author(s)
  上窪裕二、田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 35 Pages: 128-129
- Data Source
  KAKENHI-PROJECT-26430012
[Journal Article] グループII型およびIII型代謝型グルタミン酸受容体の生理的および薬理的作用2016
- Author(s)
  上窪裕二, 田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 34 Pages: 256-257
- Data Source
  KAKENHI-PROJECT-26430012
[Journal Article] 代謝型グルタミン酸受容体の構造と種類2016
- Author(s)
  上窪裕二, 田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 34 Pages: 8-9
- Data Source
  KAKENHI-PROJECT-26430012
[Journal Article] アデノシン受容体の種類とあらまし2016
- Author(s)
  田端俊英、上窪裕二
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 34 Pages: 1288-1289
- Data Source
  KAKENHI-PROJECT-26460707
[Journal Article] グループI型代謝型グルタミン酸受容体の生理的および薬理的作用2016
- Author(s)
  上窪裕二, 田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 34 Pages: 136-137
- Data Source
  KAKENHI-PROJECT-26430012
[Journal Article] Application of surface plasmon　resonance imaging to monitoring G protein-coupled receptor signaling and its modulation in a heterologous expression system2016
- Author(s)
  Yuki Nonobe, Tomoki Yokoyama, Yuji Kamikubo, Sho Yoshida, Nozomi Hisajima, Hiroaki Shinohara, Yuki Shiraishi, Takashi Sakurai and Toshihide Tabata
- Journal Title
  
  BMC Biotechnology
  
  Volume: 16：36 Issue: 1 Pages: 1-9
- DOI
  10.1186/s12896-016-0266-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26630424, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-26460707, KAKENHI-PROJECT-26430012
[Journal Article] アデノシン受容体の種類とあらまし2016
- Author(s)
  田端俊英、上窪裕二
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 34 Pages: 1288-1289
- Data Source
  KAKENHI-PROJECT-26430012
[Journal Article] Complex formation and functional interaction between adenosine A1 receptor and type-1 metabotropic glutamate receptor2015
- Author(s)
  Kamikubo Y, Tabata T, Sakairi H, Hashimoto Y, Sakurai T
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 128 Issue: 3 Pages: 125-130
- DOI
  10.1016/j.jphs.2015.06.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430012, KAKENHI-PROJECT-26460707
[Journal Article] Presynaptic protein Synaptotagmin1 regulates the neuronal polarity and axon differentiation in cultured hippocampal neurons.2015
- Author(s)
  Inoue Y, Kamikubo Y, Ezure H, Ito J, Kato Y, Moriyama H, Otsuka N.
- Journal Title
  
  BMC Neuroscience
  
  Volume: 16 Issue: 1 Pages: 92-92
- DOI
  10.1186/s12868-015-0231-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460707
[Journal Article] GPCRヘテロ複合体形成による神経伝達の制御2014
- Author(s)
  上窪裕二、田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 32 Pages: 8-9
- Data Source
  KAKENHI-PROJECT-23500384
[Journal Article] Gタンパク質共役型受容体(GPCR)総論2013
- Author(s)
  上窪裕二、清水英明
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 134-135
- Data Source
  KAKENHI-PROJECT-23700390
[Journal Article] GPCR と Gqα、Gβγシグナリング2013
- Author(s)
  上窪裕二
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 32 Pages: 502-503
- URL
  https://www.chugaiigaku.jp/modules/shop/index.php?main_page=product_info&cPath=3_75&products_id=1344
- Data Source
  KAKENHI-PROJECT-23700390
[Journal Article] GPCR へテロ複合体形成による神経伝達の制御2013
- Author(s)
  上窪裕二, 田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 32(1)2 Pages: 8-9
- Data Source
  KAKENHI-PROJECT-23500384
[Journal Article] GPCR と三量体 Gタンパク質2013
- Author(s)
  上窪裕二,清水英明
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 262-263
- URL
  https://www.chugaiigaku.jp/modules/shop/index.php?main_page=product_info&cPath=3_75&products_id=1319
- Data Source
  KAKENHI-PROJECT-23700390
[Journal Article] G タンパク質共役型受容体(GPCR)総論2013
- Author(s)
  上窪裕二,清水英明
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 134-135
- URL
  https://www.chugaiigaku.jp/modules/shop/index.php?main_page=product_info&cPath=3_75&products_id=1316
- Data Source
  KAKENHI-PROJECT-23700390
[Journal Article] GPCRとcAMPシグナリング2013
- Author(s)
  上窪裕二
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31
- Data Source
  KAKENHI-PROJECT-23700390
[Journal Article] GPCRを調節する因子2013
- Author(s)
  上窪裕二
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31
- Data Source
  KAKENHI-PROJECT-23700390
[Journal Article] GPCR と cAMP シグナリング2013
- Author(s)
  上窪裕二
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 382-383
- URL
  https://www.chugaiigaku.jp/modules/shop/index.php?main_page=product_info&cPath=3_75&products_id=1330
- Data Source
  KAKENHI-PROJECT-23700390
[Journal Article] GPCR 複合体形成2013
- Author(s)
  上窪裕二, 田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31(12) Pages: 1354-1355
- Data Source
  KAKENHI-PROJECT-23500384
[Journal Article] GPCRとGqα、Gβγシグナリング2013
- Author(s)
  上窪裕二
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31
- Data Source
  KAKENHI-PROJECT-23700390
[Journal Article] GPCRの複合体形成2013
- Author(s)
  上窪裕二、田端俊英
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 1118-1119
- Data Source
  KAKENHI-PROJECT-23500384
[Journal Article] GPCRと三量体Gタンパク質2013
- Author(s)
  上窪裕二、清水英明
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 262-263
- Data Source
  KAKENHI-PROJECT-23700390
[Journal Article] Laminin 〓lphal is essential for mouse cerebellar development2012
- Author(s)
  Ichikawa-Tomikawa N
- Journal Title
  
  Matrix Biology
  
  Volume: 31 Issue: 1 Pages: 17-28
- DOI
  10.1016/j.matbio.2011.09.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300128, KAKENHI-PROJECT-23659187, KAKENHI-PROJECT-23700390, KAKENHI-PROJECT-24790390
[Journal Article] Adenosine A1 receptor interacts with mGluR1 and regulates cerebellar LTD2011
- Author(s)
  Yuji Kamikubo, Yosuke Fujita, Takeshi Shimomura, Takaaki Miyajima, Masahiro Fujino, Toshihide Tabata, Kenkichi Fukurotani, Masanobu Kano, Takashi Sakurai
- Journal Title
  
  Neuroscience Research
  
  Volume: 71, Supplement Pages: e111-e111
- DOI
  10.1016/j.neures.2011.07.472
- Data Source
  KAKENHI-PROJECT-23700390
[Journal Article] Lidocaine attenuates the development of diabetic-induced tactile allodynia by inhibiting microglial activation2011
- Author(s)
  Suzuki N
- Journal Title
  
  Anesthesia & Analgesia
  
  Volume: 113 Issue: 4 Pages: 941-946
- DOI
  10.1213/ane.0b013e31822827a2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300128, KAKENHI-PROJECT-23700390
[Patent] アプタマー及びその用途2023
- Inventor(s)
  田端俊英、池本光志、上窪裕二
- Industrial Property Rights Holder
  学校法人　順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-010872
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K06170
[Presentation] 海馬スライス培養を用いたアミロイドプラーク形成と神経突起変性の経時的解析2023
- Author(s)
  周藝瑶, 上窪裕二, 石田葉子, 日置寛之, 櫻井隆
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K06170
[Presentation] 海馬スライス培養を用いたAPPプロッセッシングの解析プラットフォーム2023
- Author(s)
  上窪裕二, 周藝瑶, 金浩, 橋本祥江, 櫻井隆
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] シリカナノ粒子により生じる細胞内シグナルと細胞死の評価2023
- Author(s)
  山﨑響, 坂入伯駿, 上窪裕二, 櫻井隆
- Organizer
  第149回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] 初代培養神経細胞を用いたナノマテリアルの細胞毒性の解析2023
- Author(s)
  上窪裕二, 橋本祥江, 櫻井隆
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K06170
[Presentation] 脳器官培養法を用いたアミロイドβ分泌とアミロイド斑形成の経時的解析2023
- Author(s)
  上窪裕二, 周藝瑶, 櫻井隆
- Organizer
  第53回日本神経精神薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K06170
[Presentation] 神経細胞に対してナノ粒子が引き起こす細胞応答と細胞死の評価2023
- Author(s)
  坂入伯駿, 上窪裕二, 山﨑響, 橋本祥江, 櫻井隆
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K06170
[Presentation] アミロイドプラーク形成による神経突起変性の解析2023
- Author(s)
  周藝瑶, 上窪裕二, 石田葉子, 日置寛之, 櫻井隆
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] 脳スライス培養を用いたアミロイドプラーク形成と神経突起変性の解析2023
- Author(s)
  周藝瑶, 上窪裕二, 石田葉子, 日置寛之, 櫻井隆
- Organizer
  第147回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] 海馬スライス培養を用いたアミロイドプラーク形成と神経突起変性の経時的解析2023
- Author(s)
  周藝瑶, 上窪裕二, 石田葉子, 日置寛之, 櫻井隆
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] 脳器官培養法を用いたアミロイドβ分泌とアミロイド斑形成の経時的解析2023
- Author(s)
  上窪裕二, 周藝瑶, 櫻井隆
- Organizer
  第53回日本神経精神薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] 代謝型グルタミン酸受容体とGABAB受容体における異種GPCR間相互作用2023
- Author(s)
  坂入伯駿, 上窪裕二, 櫻井隆
- Organizer
  第147回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] シリカナノ粒子により生じる細胞内シグナルと細胞死の評価2023
- Author(s)
  山﨑響, 坂入伯駿, 上窪裕二, 櫻井隆
- Organizer
  第149回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-23K06170
[Presentation] 1型代謝型グルタミン酸受容体とGABAB受容体における異種GPCR間複合体形成と双方向シグナル調節2022
- Author(s)
  坂入伯駿, 上窪裕二, 田端俊英, 櫻井隆
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] 低濃度鉛曝露による離乳後の仔ラットの注意力低下への影響2021
- Author(s)
  大森由紀, 上窪裕二, 杉谷善信, 松川岳久, 小林桃子, 武藤剛, 横山和仁, 角田正史, 堀口兵剛
- Organizer
  メタルバイオサイエンス研究会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] 金属酸化物ナノ粒子の神経毒性2021
- Author(s)
  上窪裕二, 櫻井隆
- Organizer
  第44回日本神経科学大会 / CJK第1回国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] AAV2/PHP.eBベクターを用いた海馬CA2野選択的標識2021
- Author(s)
  岡本和樹, 上窪裕二, 山内健太, 岡本慎一, 高橋慧, 石田葉子, 櫻井隆, 小池正人, 池谷裕二, 日置寛之
- Organizer
  第44回日本神経科学大会 / CJK第1回国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] 代謝型グルタミン酸受容体とGABAB受容体の複合体形成とシグナルクロストーク2020
- Author(s)
  上窪裕二, 坂入伯駿, 田端俊英, 櫻井隆
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] 1 型代謝型グルタミン酸受容体と GABAB 受容体は異種 GPCR 間複合体を形成し、互いの細胞内シグナルを双方向に制御する2020
- Author(s)
  坂入伯駿，上窪裕二，田端俊英，櫻井隆
- Organizer
  薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18K06461
[Presentation] 代謝型グルタミン酸受容体と GABAB受容体の複合体形成とシグナルクロストーク2020
- Author(s)
  上窪裕二，坂入伯駿，田端俊英，櫻井隆
- Organizer
  日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K06461
[Presentation] 代謝型グルタミン酸受容体とGABAB受容体の複合体形成とシグナルクロストーク2020
- Author(s)
  上窪裕二, 坂入伯駿, 田端俊英, 櫻井隆
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] 1型代謝型グルタミン酸受容体とGABAB受容体は異種GPCR間複合体を形成し、互いの細胞内シグナルを双方向に制御する2020
- Author(s)
  坂入伯駿, 上窪裕二, 田端俊英, 櫻井隆
- Organizer
  第143回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] Type 1 metabotropic glutamate receptor 1 and GABA B receptor form complexes at cell membrane and mutually modulate their function2020
- Author(s)
  Hakushun Sakairi, Yuji Kamikubo, Toshihide Tabata, Takashi Sakurai
- Organizer
  日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06461
[Presentation] 1型代謝型グルタミン酸受容体とGABAB受容体は異種GPCR間複合体を形成し、互いの細胞内シグナルを双方向に制御する2020
- Author(s)
  坂入伯駿, 上窪裕二, 田端俊英, 櫻井隆
- Organizer
  第143回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K07765
[Presentation] シリカナノ粒子による酸化ストレスと神経細胞死2019
- Author(s)
  上窪裕二、山名智人、橋本祥江、櫻井隆
- Organizer
  第９２回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] Implementation and characterization of a non-linear filter to extract neurobiological signals with minimal distortion2019
- Author(s)
  Toshihide Tabata, Rihito Nagamatsu, Masayoshi Abe, Kazuki Kitamura, Tomoki Matsui, Ryo Takemura, Hakushun Sakairi, Yuji Kamikubo
- Organizer
  日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K06461
[Presentation] ナノマテリアルによる酸化ストレスと神経細胞死2019
- Author(s)
  上窪裕二, 山名智人, 井上由理子, 橋本祥江, 櫻井隆
- Organizer
  第42回日本神経科学大会、第62回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] 歪みを最小化しながら神経生体信号を抽出する非線形フィルターの実装と性能評価2019
- Author(s)
  田端俊英, 永松利一, 阿部匡良, 北村和希, 松井友希, 竹村諒, 坂入伯駿, 上窪裕二, 櫻井隆
- Organizer
  第42回日本神経科学大会、第62回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] 代謝型グルタミン酸受容体1型とGABAB受容体の複合体形成と機能的相互作用2019
- Author(s)
  坂入伯駿, 上窪裕二, 阿部匡良, 池田圭祐, 一木新, 田端俊英, 櫻井隆
- Organizer
  第42回日本神経科学大会、第62回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] 鉛曝露によるアストロサイトの受容体のカルシウム応答への影響2019
- Author(s)
  大森由紀、上窪裕二、松川岳久、横山和仁、堀口兵剛
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] シリカナノ粒子による酸化ストレスの誘導と神経細胞死2019
- Author(s)
  上窪裕二, 橋本祥江, 櫻井隆
- Organizer
  第140回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] Metabotropic glutamate receptor 1 (mGluR1) forms hetero-oligomer with other G-protein coupled receptors and they regulate their signal transduction each other at neurons2018
- Author(s)
  Hakushun Sakairi, Yuji Kamikubo, Masayoshi Abe, Kenta Matsuoka, Toshihide Tabata, Takashi Sakurai
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] Continuous inhibition of secretase regulates synapse formation2018
- Author(s)
  Yuji Kamikubo, Kazue Niisato, Koichi Jingo, Hao Jin, Takashi Sakurai
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] Signal crosstalk and complex formation of mGluR1 and GABAbR2018
- Author(s)
  Y. Kamikubo, H. Sakairi, T. Tabata, T. Sakurai
- Organizer
  日本生理学会大会
- Data Source
  KAKENHI-PROJECT-26430012
[Presentation] B-type GABA receptor serves as a dynamic modulator increasing the ligand-sensitivity of type-1 metabotropic glutamate receptor2018
- Author(s)
  Abe M, Ikeda K, Ichiki A, Matsuoka K, Sakairi H, Kamikubo Y, Sakurai T, Tabata T
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K06461
[Presentation] セクレターゼはシナプス発達と成熟を制御する2018
- Author(s)
  上窪裕二、新里和恵、坂入伯駿、橋本祥江、櫻井隆
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] 代謝型グルタミン酸受容体とGABAB受容体の複合体形成とシグナル・クロストーク2018
- Author(s)
  上窪裕二、坂入伯駿、田端俊英、櫻井隆
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] B型GABA受容体は動的モジュレーターとして1型代謝型グルタミン酸受容体のリガンド感受性を亢進させる2018
- Author(s)
  阿部匡良、池田圭佑、一木新、松岡希斗、坂入伯駿、上窪裕二、櫻井隆、田端俊英
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] GPCR相互作用による1型代謝型グルタミン酸受容体機能の制御2017
- Author(s)
  上窪裕二、坂入伯駿、阿部匡良、松岡希斗、田端俊英、櫻井隆
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460707
[Presentation] 低濃度の鉛曝露によるアストロサイトのカルシウムイオンおよびD,L-Serineへの影響2017
- Author(s)
  大森由紀、上窪裕二、松川岳久、横山和仁、堀口兵剛
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] 中枢神経系に発現するGPCR間の異種複合体形成と機能的相互作用2017
- Author(s)
  坂入伯駿、上窪裕二、田端俊英、櫻井隆
- Organizer
  第137回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] 強制発現系におけるmGluR1とGABABRの複合体形成と機能的相互作用2017
- Author(s)
  松岡希斗、阿部匡良、坂入伯駿、上窪裕二、櫻井隆、田端俊英
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] シナプスの発達と成熟におけるセクレターゼの作用2017
- Author(s)
  上窪裕二、新里和恵、神後宏一、橋本祥江、櫻井隆
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松
- Data Source
  KAKENHI-PROJECT-26460707
[Presentation] L-ドーパは血管のα1受容体を制御して交感神経機能を亢進させる2017
- Author(s)
  増川太輝、古賀資和、涌井広道、上窪裕二、横山詩子、中村史雄、田村功一、梅村敏、櫻井隆、石川義弘、五嶋良郎
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09040
[Presentation] Regulation of type-1 metabotropic glutamate receptors function through inter-GPCR interplay2017
- Author(s)
  Y. Kamikubo, H. Sakairi, M. Abe, K. Matsuoka, T. Tabata, T. Sakurai
- Organizer
  日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26430012
[Presentation] Complex formation and functional interaction between mGluR1 and GABAbR in a heterologous expression system2017
- Author(s)
  K. Matsuoka, M. Abe, H. Sakairi, Y. Kamikubo, T. Sakurai, T. Tabata
- Organizer
  日本神経科学大会
- Data Source
  KAKENHI-PROJECT-26430012
[Presentation] Modulation of type-1 metabotropic glutamate receptor by adenosine A1 receptor: an analysis with surface plasmon resonance imaging2016
- Author(s)
  S. Yoshida, Y. Kamikubo, H. Shinohara, Y. Shiraishi, T. Sakurai, T. Tabata
- Organizer
  日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26430012
[Presentation] 培養神経細胞および組織を用いた膜タンパク質の機能解析2016
- Author(s)
  上窪裕二
- Organizer
  第3回包括的神経グリア研究会
- Place of Presentation
  ホテルニュータカハシ（熱海）
- Year and Date
  2016-01-09
- Data Source
  KAKENHI-PROJECT-26460707
[Presentation] アデノシンA1受容体による1型代謝型グルタミン酸受容体シグナリングの変調：表面プラズモン共鳴イメージングによる解析2016
- Author(s)
  田端俊英、吉田翔、上窪裕二、篠原寛明、白石有希、櫻井隆
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-26460707
[Presentation] 代謝型グルタミン酸受容体1 型はアデノシンA1 受容体のシグナルを制御する2015
- Author(s)
  坂入伯駿、上窪裕二、櫻井隆
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18
- Data Source
  KAKENHI-PROJECT-26460707
[Presentation] Bidirectional interaction between adenosine A1 receptor and type-1 metabotropic glutamate receptor2015
- Author(s)
  Kamikubo Y, Tabata T, Sakurai T.
- Organizer
  Neuroscience 2015 45th annual neuroscience meeting
- Place of Presentation
  Chicago's McCormick Place (Chicago, Ill)
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460707
[Presentation] GPCR複合体形成による神経機能の制御2015
- Author(s)
  上窪裕二、山名智人、櫻井隆
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（神戸）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26460707
[Presentation] Bidirectional interaction between adenosine A1 receptor and type-1 metabotropic glutamate receptor2015
- Author(s)
  Kamikubo Y, Tabata T, Sakairi H, Hashimoto Y, Sakurai T
- Organizer
  Society for Neuroscience Annual Meeting
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430012
[Presentation] アデノシンA1受容体と受容体と代謝型グルタミン酸の複合形成機能的相互作用受容体と代謝型グルタミン酸の複合形成機能的相互作用2014
- Author(s)
  上窪裕二、坂入伯駿、田端俊英、櫻井隆
- Organizer
  第131回日本薬理学会関東部会
- Place of Presentation
  横浜市立大学福浦キャンパス
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-26460707
[Presentation] 海馬スライス培養系を用いたβセクレターゼ活性の解析2014
- Author(s)
  上窪裕二、櫻井隆
- Organizer
  第35回日本神経科学大会 (Neuroscience2012)
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-23300128
[Presentation] アデノシンA1受容体と代謝型グルタミン酸受容体の複合体形成と機能的相互作用2014
- Author(s)
  上窪裕二, 坂入伯駿, 田端俊英, 櫻井隆
- Organizer
  日本薬理学会関東部会
- Place of Presentation
  横浜
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-26430012
[Presentation] 海馬スライス培養系を用いたβセクレターゼ活性の解析2014
- Author(s)
  上窪裕二,櫻井隆
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26460707
[Presentation] 異種GPCR間の相互作用による神経伝達の制御2013
- Author(s)
  坂入伯駿,上窪裕二,櫻井隆
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-23700390
[Presentation] 切断端認識抗体を用いたニューレグリン１のBACE1切断依存的細胞間シグナル伝達の解析2013
- Author(s)
  樫山拓,上窪裕二,櫻井隆
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-23700390
[Presentation] 海馬切片培養標本を用いたアミロイドβ産生の評価2013
- Author(s)
  上窪裕二,櫻井隆
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-23700390
[Presentation] mGluR1-アデノシンA1受容体相互作用とシグナル・クロストーク2012
- Author(s)
  上窪裕二,櫻井隆
- Organizer
  第35回日本神経科学大会(Neuroscience2012)
- Place of Presentation
  名古屋国際会議場（愛知）
- Data Source
  KAKENHI-PROJECT-23700390
[Presentation] アデノシンA1受容体と1型代謝型グルタミン酸受容体の複合体形成によるシグナル・クロストーク2012
- Author(s)
  上窪裕二
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-23300128
[Presentation] アデノシンA1受容体と代謝型グルタミン酸受容体の相互作用による小脳LTDの調整2011
- Author(s)
  上窪裕二、藤田洋介、下村岳司、宮島隆彰、藤野真弘、田端俊英、袋谷賢吉、狩野方伸
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23500384
[Presentation] アデノシンA1受容体と代謝型グルタミン酸受容体の相互作用による小脳LTDの調節2011
- Author(s)
  上窪裕二
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23300128
[Presentation] アデノシンA1 受容体と代謝型グルタミン酸受容体の相互作用による小脳LTDの調整2011
- Author(s)
  上窪裕二, 藤田洋介, 下村岳司, 宮島隆彰, 藤野真弘, 田端俊英, 袋谷賢吉, 狩野方伸
- Organizer
  日本神経科学大会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23500384
[Presentation] 代謝型グルタミン酸受容体(mGluR1)とアデノシンA1受容体(A1R)相互作用による小脳LTDの制御2010
- Author(s)
  上窪裕二
- Organizer
  Neuro2010(神経科学会・神経化学会・神経回路学会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20300125
[Presentation] 代謝型グルタミン酸受容体(mGluR1)とアデノシンA1受容体(A1R)相互作用による小脳LTDの制御2010
- Author(s)
  上窪裕二
- Organizer
  Neuro2010(神経科学会・神経化学会・神経回路学会合同大会)
- Place of Presentation
  神戸コンベンションセンター(兵庫)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21700359
[Presentation] 代謝型グルタミン酸受容体(mGluR1)とアデノシンA1受容体(A1R)相互作用による小脳LTDの制御2010
- Author(s)
  上窪裕二
- Organizer
  Neuro2010(神経科学会・神経化学会・神経回路学会合同大会)
- Place of Presentation
  神戸コンベンションセンター(兵庫)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21700359
[Presentation] A1アデノシン受容体とmGluR1のシグナル・クロストークによる小脳LTDの制御2010
- Author(s)
  上窪裕二
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21700359
[Presentation] Adenosine A1 receptor regulates mGluR1 signaling and LTD in cerebellar Purkinje cells2009
- Author(s)
  上窪裕二
- Organizer
  Neuroscience 2009 39th annual neuroscience meeting
- Place of Presentation
  Chicago's McCormick Place(Chicago)
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-21700359
[Presentation] Adenosine A1 receptor regulates mGluR1 signaling and LTD in cerebellar Purkinje cells2009
- Author(s)
  Y.Kamikubo
- Organizer
  Neuroscience 2009 39th annual neuroscience meeting (Society for Neuroscience)
- Place of Presentation
  Chicago's McCormick Place (Chicago、 Ill)
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-21700359
[Presentation] Bi-directional regulation of cerebellar synaptic plasticity through inter-GPCR interplay2009
- Author(s)
  Y.Kamikubo
- Organizer
  International Congress of Physiological Sciences(IUPS2009)
- Place of Presentation
  Kyoto International Conference Center (Kyoto)
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-21700359
[Presentation] 海馬切片培養標本を用いたβ-セクレターゼの解析
- Author(s)
  上窪裕二、櫻井隆
- Organizer
  第36回日本神経科学大会 Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23300128
[Presentation] 海馬スライス培養標本を用いたβ-セクレターゼ機能の評価
- Author(s)
  上窪裕二、櫻井隆
- Organizer
  第128回日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23300128
[Presentation] アデノシンA1受容体による代謝型グルタミン酸受容体と小脳長期抑圧の制御
- Author(s)
  上窪裕二
- Organizer
  第84回日本薬理学会年会、誌上発表
- Data Source
  KAKENHI-PROJECT-21700359
[Presentation] アデノシンA1受容体と代謝型グルタミン酸受容体の相互作用による小脳LTDの調節
- Author(s)
  上窪裕二，藤田洋介，下村岳司，宮島隆彰，田端俊英，袋谷賢吉，狩野方伸
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-23700390
[Presentation] APP-βCTFに特異的に結合するエンドソーム蛋白質の解析
- Author(s)
  高杉展正、新家瑠奈、上窪裕二、櫻井隆
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23300128
[Presentation] 海馬切片培養標本を用いたアミロイドβ産生の評価
- Author(s)
  上窪裕二
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300128
[Presentation] mGluR1-アデノシンA1受容体相互作用とシグナル・クロストーク
- Author(s)
  上窪裕二
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-23300128
[Presentation] アデノシンA1受容体と1型代謝型グルタミン酸受容体の複合体形成によるシグナル・クロストーク
- Author(s)
  上窪裕二，櫻井隆
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23700390
[]
[]

1. TABATA Toshihide (80303270)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
2. SAKURAI Takashi (70225845)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NUKINA Nobuyuki (10134595)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KASHIYAMA Taku (90338343)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. ARAYA Runa (10391848)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. TAKASUGI Nobumasa (60436590)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. MURAYAMA Takashi (10230012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. INADA Eiichi (40193552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHINOHARA Hiroaki (60178887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 長谷川麻衣子 (20516637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 冨永光俊 (50468592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 石田良典 (10937684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. YOKOYAMA Tomoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. FUKUSHIMA Toshiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Goshima Yoshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. OHNUMA Kei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 桜井正樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
18. 井上明男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 伊藤純治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 井上由理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 富田泰輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 伊藤弦太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 岡本和樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 中村史雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 波多野良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 森本幾夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 山口啓介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 井関雅子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 橋本唯史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kamikubo yuuji 上窪 裕二

KAMIKUBO Yuji 上窪 裕二

Research Projects

Research Products

Co-Researchers

GPCR超複合体機能の定量的網羅的解析Principal Investigator

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Manipulation of membrane protein supercomplexes to elucidate their molecular dynamics and functionPrincipal Investigator

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GPCR-Amyloid precursor protein supercomplex regulate neural functionPrincipal Investigator

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Analysis of the regulatory mechanism of motor learning using real-time FRET and fast-scan voltammetry

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Inter-GPCR interplay regulate intractable itch.Principal Investigator

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Regulation of pain through inter-GPCR interplayPrincipal Investigator

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Regulation of synaptic plasticity via hetero-GPCR modulation: an analysis using surface plasmon resonance imaging

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Microdomain-dependent acceleration mechanisms for amyloidogenic processing of amyloid precursor protein induced by endocytic membrane traffic impairment

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Influence of ambient neuromodulators on learning through hetero-GPCR interplay

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Adenosine A1 receptor interacts with mGluR1 and regulates motor learningPrincipal Investigator

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Regulation of synaptic plasticity through inter-GPCR interplayPrincipal Investigator

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A novel microdomain-dependent regulatory mechanism of amyloid precursor protein processing

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[Book] エース薬理学2020

Author(s)

Total Pages

kamikubo yuuji 上窪裕二

KAMIKUBO Yuji 上窪裕二