Oda Akihisa 小田朗永

… Alternative Names

Researcher Number	80547703
Other IDs
Affiliation (Current)	2021: 奈良県立医科大学, 医学部, 特任助教
Affiliation (based on the past Project Information) *help	2019 – 2021: 奈良県立医科大学, 医学部, 特任助教 2018: 東京理科大学, 研究推進機構生命医科学研究所, 研究員 2015 – 2016: 東京理科大学, 研究推進機構生命医科学研究所, 助教 2013: 東京理科大学, 生命医科学研究所, 助教 2012: 信州大学, 医学部, 研究員 2010: Shinshu University, 医学部, 研究員 2009 – 2010: Shinshu University, 医学系研究科, 研究員
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Medium-sized Section 52:General internal medicine and related fields / Basic Section 55060:Emergency medicine-related
Keywords	Principal Investigator 間葉系幹細胞 / 好塩基球 / IL-4 / PIR-B / Th2 / Tlx1 / 脾臓 / 脾臓微小環境 / 間葉系前駆細胞 / 髄外造血 … More Except Principal Investigator 血友病A / iPS細胞 / 細胞シート / 第VIII因子 / 細胞治療 / ARDS / 血管内皮細胞 / SETDB2 Less

血友病Aインヒビター産生応答を制御する脾臓免疫ニッチの同定Principal InvestigatorOngoing
- Principal Investigator
  
  小田朗永
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nara Medical University
Development of Universal Cell Therapy for Hemophilia A Ongoing
- Principal Investigator
  
  嶋緑倫
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nara Medical University
血管内皮細胞からARDSの病態を解明する-ヒストン修飾酵素SETDB2の意義-Ongoing
- Principal Investigator
  
  園部奨太
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Nara Medical University
脾臓髄外造血制御とその破綻の分子機構解明と造血幹細胞培養系の確立Principal InvestigatorOngoing
- Principal Investigator
  
  小田朗永
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Nara Medical University
  Tokyo University of Science
The role of the mesenchymal cells expressing Tlx1 in the adult spleenPrincipal Investigator
- Principal Investigator
  
  Akihisa Oda
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
The regulatory mechanism for interleukin-4 induction in murine basophilsPrincipal Investigator
- Principal Investigator
  
  ODA Akihisa
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
  Shinshu University
Signaling pathway for interleukin-4 induction in basophilsPrincipal Investigator
- Principal Investigator
  
  ODA Akihisa
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  Shinshu University

All 2019 2018 2017 2016 2015 2013 2010 2009

All Journal Article Presentation Book

[Book] 脾臓髄外造血と生体造血ニッチの変遷2019
- Author(s)
  小田朗永
- Total Pages
  7
- Publisher
  科学評論社
- ISBN
- Data Source
  KAKENHI-PROJECT-18K07182
[Book] 成体脾臓における髄外造血ニッチとその構成要素2018
- Author(s)
  小田朗永、後飯塚僚
- Total Pages
  2
- Publisher
  医歯薬出版株式会社
- ISBN
  4910204730183
- Data Source
  KAKENHI-PROJECT-18K07182
[Book] 臨床免疫・アレルギー科2010
- Author(s)
  小田朗永、瀧伸介
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-21890092
[Book] 好塩基球におけるIL-4産生誘導シグナルとTh2分化2010
- Author(s)
  小田朗永、瀧伸介
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-21890092
[Journal Article] Transcription factor Tlx1 marks a subset of lymphoid tissue organizer-like mesenchymal progenitor cells in the neonatal spleen2019
- Author(s)
  Ueno Yuta、Fujisaki Keiko、Hosoda Shoko、Amemiya Yusuke、Okazaki Shogo、Notsu Chihiro、Nishiyama Chiharu、Mabuchi Yo、Matsuzaki Yumi、Oda Akihisa、Goitsuka Ryo
- Journal Title
  
  Sci Rep
  
  Volume: 9 Pages: 20408-20408
- DOI
  10.1038/s41598-019-56984-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01753, KAKENHI-PROJECT-18K07182, KAKENHI-PROJECT-19K10024, KAKENHI-PROJECT-18KK0449, KAKENHI-PROJECT-19KK0216, KAKENHI-PROJECT-18K15223
[Journal Article] Niche-induced extramedullary hematopoiesis in the spleen is regulated by the transcription factor Tlx1.2018
- Author(s)
  Oda A, Ueno Y, Hosoda S, Amemiya Y, Notsu C, Tezuka T, Kasahara T, Nishiyama C, Goitsuka R
- Journal Title
  
  Sci Rep.
  
  Volume: 29 Pages: 8308-8308
- DOI
  10.1038/s41598-018-26693-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07182, KAKENHI-PROJECT-16H05047
[Journal Article] Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow.2015
- Author(s)
  Yoshioka K, Oda A, Notsu C, Ohtsuka T, Kawai Y, Suzuki S, Nakamura T, Mabuchi Y, Matsuzaki Y, Goitsuka R.
- Journal Title
  
  PLoS One
  
  Volume: 10(8)
- DOI
  10.1371/journal.pone.0136107
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06853, KAKENHI-PROJECT-15K19136, KAKENHI-PROJECT-26660259, KAKENHI-PROJECT-25292194
[Presentation] The contribution of histone-lysine N-methyltransferase Setdb2 in high mortality of secondary bacterial pneumonia via regulating cytokines and chemokines in macrophages.2019
- Author(s)
  Atsushi Hara, Masahiro Kitabatake, Noriko Ouji-Sageshima, Shota Sonobe, Natsuko Imakita, Ryutaro Furukawa, Akihisa Oda, Toshihiro Ito
- Organizer
  第48回　日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07182
[Presentation] Transcription factor Tlx1 regulates a niche for innate-like B cells in the spleen.2018
- Author(s)
  Shoko Hosoda, Keiko Fujisaki, Yuta Ueno, Chiharu Nishiyama, Hei Haniuda, Akihisa Oda, Daisuke Kitamura, Ryo Goitsuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07182
[Presentation] Abnormality in the splenic microenvironment is involved in the malignant transformation of acute myeloid leukemia.2018
- Author(s)
  Yusuka Amemiya, Chiharu Nishiyama, Akihisa Oda, Takuro Nakamura, Ryo Goitsuka
- Organizer
  第47回日本免疫学会学術集会,
- Data Source
  KAKENHI-PROJECT-18K07182
[Presentation] 脾臓髄外造血制御の破綻は骨髄増殖性疾患の発症に関与する.2018
- Author(s)
  小田朗永
- Organizer
  第83回日本インターフェロン・サイトカイン学術集会
- Data Source
  KAKENHI-PROJECT-18K07182
[Presentation] The spleen serves as a specific microenvironment that support development of B-1a cells and LAG-3+ CD138+ natural regulatory plasma cells.2018
- Author(s)
  Akihisa Oda, Keiko Fujisaki, Yuta Ueno, Chiharu Nishiyama, Ryo Goitsuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07182
[Presentation] Transcription factor Tlx1 is involved in the postnatal splenic architectural maintenance in a non-cell autonomous manner.2018
- Author(s)
  Yuta Ueno, Chiharu Nishiyama, Akihisa Oda, Ryo Goitsuka
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07182
[Presentation] 骨髄増殖性疾患発症における脾臓微小環境の役割2018
- Author(s)
  小田朗永, 雨宮祐輔, 後飯塚僚
- Organizer
  第28回学術集会Kyoto T cell conference
- Data Source
  KAKENHI-PROJECT-18K07182
[Presentation] 三次元培養法を用いた脾臓 Lymphoid tissue organizer like細胞の解析2018
- Author(s)
  上野湧太, 小田朗永, 西山千春, 後飯塚僚
- Organizer
  第83回日本インターフェロン・サイトカイン学術集会
- Data Source
  KAKENHI-PROJECT-18K07182
[Presentation] The cell components of perifollicular hematopoietic niche in the spleen.2017
- Author(s)
  Akihisa Oda, and Ryo Goitsuka
- Organizer
  7th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  京都大学芝蘭会館 (京都)
- Year and Date
  2017-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19136
[Presentation] Interdependent roles of Tlx1-expressing mesenchymals cells and macrophages in extramedullary hematopoiesis in the spleen.2016
- Author(s)
  6. Akihisa Oda, Toshiki Tezuka, Toru Kasahara, Yuta Ueno, Chiharu Nishiyama, and Ryo Goitsuka
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19136
[Presentation] Mesenchymal cells expressing Tlx1 serve as an extramedullary niche in the spleen.2016
- Author(s)
  Akihisa Oda, Toru Kasahara, and Ryo Goitsuka
- Organizer
  International Congress of Immunology 2016
- Place of Presentation
  メルボルン (オーストラリア)
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19136
[Presentation] 脾臓における髄外造血の間葉系ストローマ細胞とマクロファージによる制御2016
- Author(s)
  小田朗永、野津智尋、後飯塚僚
- Organizer
  第26回学術集会Kyoto T cell conference
- Place of Presentation
  延暦寺会館 (滋賀)
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15K19136
[Presentation] The splenic marginal sinus consists of two distinct cell populations expressing MAdCAM-1.2016
- Author(s)
  7. Toru Kasahara, Akihisa Oda, Toshiki Tezuka and Ryo Goitsuka
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19136
[Presentation] ホメオドメイン転写因子Tlx1は赤脾髄における赤芽球・マクロファージの維持に関与する2015
- Author(s)
  小田朗永
- Organizer
  第25回 Kyoto T Cell Conference
- Place of Presentation
  京都大学芝蘭会館
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-15K19136
[Presentation] ホメオドメイン転写因子Tlx1は脾臓原基間葉系細胞の分化運命を規定する2015
- Author(s)
  笠原透、中原亮、野津智尋、小田朗永、後飯塚僚
- Organizer
  第25回 Kyoto T Cell Conference
- Place of Presentation
  京都大学芝蘭会館
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-15K19136
[Presentation] Over-expression of Tlx1 in situ induces extramedullary hematopoiesis in the spleen2015
- Author(s)
  Akihisa Oda, Chihiro Notsu, Toru Kasahara, Ryo Goitsuka
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19136
[Presentation] The postnatal mesenchymal cell population retaining a potential to give rise to various types of mature stromal cells in the spleen2015
- Author(s)
  Akihisa Oda, Ryo Nakahara, Chihiro Notsu, Toru Kasahara, and Ryo Goitsuka
- Organizer
  Venice Thymus Meeting 2015 (Italy)
- Place of Presentation
  Venice International University (Italy)
- Year and Date
  2015-04-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19136
[Presentation] Homeodomain transcription factor Tlx1 marks a unique population of postnatal spleen mesenchymal cells2013
- Author(s)
  Nakahara, R., Oda, A. and Notsu, C., and Goitsuka, R.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24790467
[Presentation] Developmental regulation of the splenic microenvironment by mesenchymal cells expressing homeodomain transcription factor Tlx1.2013
- Author(s)
  小田朗永
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790467
[Presentation] Developmental regulation of the splenic microenvironment by mesenchymal cells expressing homeodomain transcription factor Tlx12013
- Author(s)
  Oda, A., Notsu, C., Nakahara, R. and Goitsuka, R.
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790467
[Presentation] Perivascular mural cells in the postnatal spleen express homeodomain transcription factor Tlx12013
- Author(s)
  Nakahara, R., Oda, A. and Notsu, C., and Goitsuka, R.
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790467
[Presentation] Mesenchymal progenitor-like cells in the neonatal spleen identified by homeodomain transcription factor Tlx12013
- Author(s)
  Notsu, C., Oda, A., Nakahara, R. and Goitsuka, R.
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790467
[Presentation] Paired immunoglobuhin-likereceptor(PIR)-B attenuates IL-3-induced IL-4production inanovel ITIM-independent manner in murine basophils.2010
- Author(s)
  A.ODA, Y.SAKAMOTO, T.TAKAI, S.HIDA, S.TAKI
- Organizer
  14^<th>International Congress of Immunology 2010
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21890092
[Presentation] Basophils sense various external signals with their FcRg-associated cell surface molecule(s) to produce IL-4 in eliciting Th2 responses2010
- Author(s)
  Shigeaki Hida, Akihisa Oda, Ippei Koshi, Shinsuke Taki
- Organizer
  14th International Congress of Immunology 2010
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21890092
[Presentation] Paired immunoglobulin-like receptor (PIR)-B attenuates IL-3-induced IL-4 production in a novel ITIM-independent manner in murine basophils.2010
- Author(s)
  Akihisa Oda, Yuzuru Sakamoto, Toshiyuki Takai、Shigeaki Hida, Shinsuke Taki
- Organizer
  14th International Congress of Immunology2010
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21890092
[Presentation] Paired immunoglobukin-like receptor (PIR)-B attenuates IL-3-induced IL-4 production in a novel ITIM-independent manner in murine basophils.2009
- Author(s)
  Yuzuru Sakamoto, Akihisa Oda、Toshiyuki Takai、Shigeaki Hida、Shinsuke Taki
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21890092
[Presentation] Paired immunoglobulin-like receptor (PIR)-B attenuates IL-3-induced IL-4 production in a novel ITIM-independent manner in murine basophils.2009
- Author(s)
  坂本譲、小田朗永
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21890092

1. 北畠正大 (60457588)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 嶋緑倫 (30162663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 堀江恭二 (30333446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 辰巳公平 (70555432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 荻原建一 (50623500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 坂田飛鳥 (90528457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 園部奨太 (90771808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 野上恵嗣 (50326328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KAWAI Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 馬渕洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 岡崎章悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 後飯塚僚

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 松崎有未

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oda Akihisa 小田 朗永

小田 朗永 オダ アキヒサ

Akihisa Oda 小田 朗永

ODA Akihisa 小田 朗永

Research Projects

Research Products

Co-Researchers

血友病Aインヒビター産生応答を制御する脾臓免疫ニッチの同定Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Universal Cell Therapy for Hemophilia A&#160;Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

血管内皮細胞からARDSの病態を解明する-ヒストン修飾酵素SETDB2の意義-Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脾臓髄外造血制御とその破綻の分子機構解明と造血幹細胞培養系の確立Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of the mesenchymal cells expressing Tlx1 in the adult spleenPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The regulatory mechanism for interleukin-4 induction in murine basophilsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Signaling pathway for interleukin-4 induction in basophilsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 脾臓髄外造血と生体造血ニッチの変遷2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 成体脾臓における髄外造血ニッチとその構成要素2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 臨床免疫・アレルギー科2010

Author(s)

Publisher

Data Source

[Book] 好塩基球におけるIL-4産生誘導シグナルとTh2分化2010

Author(s)

Publisher

Data Source

[Journal Article] Transcription factor Tlx1 marks a subset of lymphoid tissue organizer-like mesenchymal progenitor cells in the neonatal spleen2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Niche-induced extramedullary hematopoiesis in the spleen is regulated by the transcription factor Tlx1.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow.2015

Oda Akihisa 小田朗永

小田朗永オダアキヒサ

Akihisa Oda 小田朗永

ODA Akihisa 小田朗永

Development of Universal Cell Therapy for Hemophilia A Ongoing