Kiyoi Hitoshi 清井仁

… Alternative Names

KIYOI Hitoshi 清井仁

Less

Researcher Number	90314004
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 名古屋大学, 医学系研究科, 教授 2017 – 2019: 名古屋大学, 医学系研究科, 教授 2014 – 2015: 名古屋大学, 大学院医学系研究科, 教授 2014: 名古屋大学, 医学(系)研究科(研究院), 教授 2012 – 2013: 名古屋大学, 医学(系)研究科(研究院), 准教授 … More 2011: 名古屋大学, 医学系研究科, 准教授 2011: 名古屋大学, 大学院・医学系研究科, 准教授 2009 – 2010: Nagoya University, 医学部附属病院, 講師 2007 – 2008: Nagoya University, 医学部・附属病院, 講師 2002 – 2007: Nagoya University, University Hospital, Assistant Professor, 医学部附属病院, 講師 2004: 名古屋大学, 医学部付属病院, 講師 2001 – 2002: University Hospital, Nagoya University, Assistant Professor, 医学部・附属病院, 講師 2000: 名古屋大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Hematology / Biological Sciences / Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Hematology / Hematology
Keywords	Principal Investigator 白血病 / FLT3 / 分子標的療法 / チロシンキナーゼ / 阻害剤 / シグナル伝達 / leukemia / 分子標的薬 / 急性骨髄性白血病 / 遺伝子変異 … More / tandem duplication / 耐性機構 / 分子異常 / クローン選択 / 耐性クローン / 血液内科 / 分子標的治療 / 耐性 / signal transduction / mutation / Nucleouhosmin / ヌクレオフォスミン / Inhibitor / Tyrosinekinase / Molecular target therapy / Leukemia / genetic mutation / molecular target therapy / tyrosinekinase / Tyrosine kinase / point mutation / 点突然変異 / trandem duplication / 血液腫瘍学 / 併用療法 / 細胞内局在 / 糖鎖修飾 / キナーゼ / サロゲートマーカー / 薬剤反応性 / 遺伝子 / 予後因子 / 遺伝子異常 / 遺伝子多型 / 薬剤代謝酵素 … More Except Principal Investigator FLT3 / N-CoR / PML-RARα / hemostasis / thrombosis / coronary artery / portal vein / Genetically altered mice / Tissue factor / Antithrombin / JAK3 / JAK2 / transgenic mouse / 分子標的療法 / 白血病 / シグナル伝達 / Histone deacetylases / Acute leukemia / Transcription regulators / Transcription factors / APL / HDAC3 / ヒストン脱アセチル化酵素 / 急性白血病 / 転写調節因子 / 転写因子 / transgenic muse / 凝固異常症 / 血栓症 / アンチトロンビン / ノックアウトマウス / 組織因子 / surrogate marker / target therapy / cell signaling / leukemia / チロシンキナーゼ / 発現クローニング法 / キナーゼ阻害剤 / 変異 / ヌクレオフォスミン / 造血器腫瘍 / サロゲートマーカー / 標的治療 / Molecularly targeted thrapy / Leukemia / 変異FLT3 / 骨髄移植モデル / トランスジェニックマウス / トランスレーショナルリサーチ / 癌 / 中鎖脂肪酸誘導体 / pyruvinium pamoate / STAT3/5阻害剤 / 分子標的剤 / FLT3阻害剤 / ヒストン修飾 / 遺伝子変異 / 末梢血遊離DNA / 網羅的遺伝子変異解析 / 末梢血無細胞遊離核酸 / エピゲノム / 網羅的解析 / 遺伝子異常 / 悪性リンパ腫 / 分子イメージング / 薬剤耐性 / エピジェネティクス / 分子標的治療 / 抗体療法 / リツキシマブ / CD20 Less

Elucidation and overcoming molecular abnormalities associated with selection and resistance of acute myeloid leukemia clones through the molecularly targeted therapy.Principal Investigator
- Principal Investigator
  
  清井仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nagoya University
Molecular pathologic elucidation to become usefulness and the choice grounds of the novel FLT3 inhibitorPrincipal Investigator
- Principal Investigator
  
  Kiyoi Hitoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Translational research toward drug discovery of leukemia
- Principal Investigator
  
  NAOE Tomoki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  National Hospital Organization Nagoya Medical Center
Analysis of ligand dependent resistance mechanism of RTK inhibitorsPrincipal Investigator
- Principal Investigator
  
  KIYOI Hitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Genetic and epigenetic abnormalities in malignant lymphoma.
- Principal Investigator
  
  TOMITA AKIHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Increase of the target inhibition effects on FLT3 based on the glycosylation and cellular localization statusPrincipal Investigator
- Principal Investigator
  
  KIYOI Hitoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
キナーゼ阻害剤感受性パネルに基づく白血病の層別化Principal Investigator
- Principal Investigator
  
  清井仁
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Analyses of the mechanisms of resistance to monoclonal antibody therapy and exploration of overcoming strategies.
- Principal Investigator
  
  TOMITA Akihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
チロシンキナーゼ阻害剤の至適併用療法を予測するサロゲートマーカーの確立Principal Investigator
- Principal Investigator
  
  清井仁
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Analysis of the biojogicel effect of the nudeophcsmin gene mutation on development and progression of leukemiaPrincipal Investigator
- Principal Investigator
  
  KIYOI Hitoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
チロシンキナーゼ阻害剤の感受性を予測するサロゲートマーカーの確立Principal Investigator
- Principal Investigator
  
  清井仁
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Analyses of Transcription Co-repressor Complexes Involved in Differentiation Block of Leukemia Cells, and Development of a New Molecular Targeting Therapy.
- Principal Investigator
  
  TOMITA Akihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Analysis of aberrant signal tansduction in hematological malignancy and development of treatment methods.
- Principal Investigator
  
  NAOE Tomoki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Basic research for clinical application of a novel FLT3 inhibitor and development of a model mouse for the evaluation of anti-leukemia cell effect.Principal Investigator
- Principal Investigator
  
  KIYOI Hitoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Fatal thrombosis of antithrombin deficient mice is rescued differently in the heart and liver by intercrossing with low tissue factor mice
- Principal Investigator
  
  MATSUSHITA Tadashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Basic investigation for the development of a novel anti-leukemic therapy targeting to the mutant FLT3 molecule.Principal Investigator
- Principal Investigator
  
  KIYOI Hitoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
薬物代謝酵素遺伝子多型と発現遺伝子プロファイルによる急性白血病の層別化Principal Investigator
- Principal Investigator
  
  清井仁
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Establishment of a leukemia model mouse by introducing mutated FLT3 gene
- Principal Investigator
  
  NAOE Tomoki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Analysis of the deregulation mechanism on cell growth and differentiation induced by mutant ELT3Principal Investigator
- Principal Investigator
  
  KIYOI Hitoshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University

[Book] 新しい診断と治療のABC 急性白血病2006
- Author(s)
  清井仁
- Total Pages
  274
- Publisher
  最新医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591054
[Journal Article] Outcomes of transplant-eligible patients with myelodysplastic syndrome with excess blasts registered in an observational study: The JALSG-CS11-MDS-SCT2024
- Author(s)
  Nakagawa N, Ishiyama K, Usuki K, Takada S, Tomikawa T, Handa H, Katsuoka Y, Hirano D, Sezaki N, Sumi M, Fujisawa S, Taniguchi Y, Mugitani A, Yoshimura T, Ohtsuka E, Takase K, Suehiro Y, Ota S, Kajiguchi T, Maeda T, Yamamoto M, Ohtake S, Katsumi A, Kiyoi H, Matsumura I, Miyazaki Y.
- Journal Title
  
  Ann Hematol.
  
  Volume: 103 Issue: 1 Pages: 307-320
- DOI
  10.1007/s00277-023-05527-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08518, KAKENHI-PROJECT-23K27624
[Journal Article] Utility of allogeneic stem cell transplantation for adult Ph+ALL with complete molecular remission2024
- Author(s)
  Nishiwaki S, Sugiura I, Fujisawa S, Hatta Y, Atsuta Y, Doki N, Kurahashi S, Ueda Y, Dobashi N, Maeda T, Matsumura I, Tanaka M, Kako S, Ichinohe T, Fukuda T, Ohtake S, Ishikawa Y, Miyazaki Y, Kiyoi H
- Journal Title
  
  American Journal of Hematology
  
  Volume: 99 Issue: 5 Pages: 806-815
- DOI
  10.1002/ajh.27237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K27624
[Journal Article] Epstein-Barr virus lytic gene BNRF1 promotes B-cell lymphomagenesis via IFI27 upregulation2024
- Author(s)
  Sagou Ken、Sato Yoshitaka、Okuno Yusuke、Watanabe Takahiro、Inagaki Tomoki、Motooka Yashiro、Toyokuni Shinya、Murata Takayuki、Kiyoi Hitoshi、Kimura Hiroshi
- Journal Title
  
  PLOS Pathogens
  
  Volume: 20 Issue: 2 Pages: e1011954-e1011954
- DOI
  10.1371/journal.ppat.1011954
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06559, KAKENHI-PROJECT-21K15449, KAKENHI-PROJECT-23K27624
[Journal Article] Improved Long-Term Net Survival after Allogeneic Hematopoietic Cell Transplantation in Patients with Hematologic Malignancies over Two Decades2023
- Author(s)
  Ohbiki Marie、Ito Yuri、Inamoto Yoshihiro、Miyamura Koichi、Uchida Naoyuki、Fukuda Takahiro、Fujiwara Hiroki、Nishida Tetsuya、Hayashi Masayasu、Tanaka Masatsugu、Kawakita Toshiro、Ikegame Kazuhiro、Katayama Yuta、Ara Takahide、Ichinohe Tatsuo、Kiyoi Hitoshi、Matsuo Keitaro、Atsuta Yoshiko
- Journal Title
  
  Transplantation and Cellular Therapy
  
  Volume: 29 Issue: 12 Pages: 768.e1-768.e10
- DOI
  10.1016/j.jtct.2023.09.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21510, KAKENHI-PROJECT-23K27624
[Journal Article] High-risk Combinations of Additional Chromosomal Abnormalities in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia: JALSG Ph+ALL TKI-SCT Study2023
- Author(s)
  Nakagawa N, Ishiyama K, Usuki K, Takada S, Tomikawa T, Handa H, Katsuoka Y, Hirano D, Sezaki N, Sumi M, Fujisawa S, Taniguchi Y, Mugitani A, Yoshimura T, Ohtsuka E, Takase K, Suehiro Y, Ota S, Kajiguchi T, Maeda T, Yamamoto M, Ohtake S, Katsumi A, Kiyoi H, Matsumura I, Miyazaki Y.
- Journal Title
  
  HemaSphere
  
  Volume: 7 Issue: 6 Pages: e899-e899
- DOI
  10.1097/hs9.0000000000000899
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-23K27624
[Journal Article] Suppression of super-enhancer-driven TAL1 expression by KLF4 in T-cell acute lymphoblastic leukemia2023
- Author(s)
  Noura Mina、Matsuo Hidemasa、Yasuda Takahiko、Tsuzuki Shinobu、Kiyoi Hitoshi、Hayakawa Fumihiko
- Journal Title
  
  Oncogene
  
  Volume: 43 Issue: 6 Pages: 447-456
- DOI
  10.1038/s41388-023-02913-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15298, KAKENHI-PROJECT-22K08475, KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-23K27624
[Journal Article] Dual CAR-T Cells Targeting CD19 and CD37 Are Effective in Target Antigen Loss B-cell Tumor Models2023
- Author(s)
  Imai Kanae、Takeuchi Yuki、Terakura Seitaro、Okuno Shingo、Adachi Yoshitaka、Osaki Masahide、Umemura Koji、Hanajiri Ryo、Shimada Kazuyuki、Murata Makoto、Kiyoi Hitoshi
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 23 Issue: 3 Pages: 381-393
- DOI
  10.1158/1535-7163.mct-23-0408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08501, KAKENHI-PROJECT-21K08387, KAKENHI-PROJECT-23K27624
[Journal Article] Clonal hematopoiesis of a novel dic(18;20) clone following allogeneic hematopoietic stem cell transplantation2023
- Author(s)
  Ito Makoto、Fukushima Nobuaki、Fujii Tomoki、Numata Masaya、Morikawa Shiori、Kawamura Yuma、Goto Miyo、Kohno Akio、Imahashi Nobuhiko、Yasuda Takahiko、Sanada Masashi、Ishikawa Yuichi、Kiyoi Hitoshi、Ozeki Kazutaka
- Journal Title
  
  International Journal of Hematology
  
  Volume: 119 Issue: 1 Pages: 80-87
- DOI
  10.1007/s12185-023-03673-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-23K27624
[Journal Article] Nelarabine, intensive L-asparaginase, and protracted intrathecal therapy for newly diagnosed T-cell acute lymphoblastic leukaemia in children and young adults (ALL-T11): a nationwide, multicenter, phase 2 trial including randomisation in the very high-risk group2023
- Author(s)
  Sato Atsushi、Hatta Yoshihiro、Imai Chihaya、Oshima Koichi、Okamoto Yasuhiro、Deguchi Takao、Hashii Yoshiko、Fukushima Takashi、Hori Toshinori、Kiyokawa Nobutaka、Kato Motohiro、Saito Shoji、Anami Kenichi、Sakamoto Tatsuhiro、Kosaka Yoshiyuki、Suenobu Souichi、et al.
- Journal Title
  
  The Lancet Haematology
  
  Volume: 10 Issue: 6 Pages: e419-e432
- DOI
  10.1016/s2352-3026(23)00072-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07866, KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-18K07822, KAKENHI-PROJECT-21K07851, KAKENHI-PROJECT-23K24297, KAKENHI-PROJECT-23K27624
[Journal Article] Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation2023
- Author(s)
  Kurayoshi K, Takase Y, Ueno M, Ohta K, Fuse K, Ikeda S, Watanabe T, Nishida Y, Horike SI, Hosomichi K, Ishikawa Y, Tadokoro Y, Kobayashi M, Kasahara A, Jing Y, Shoulkamy MI, Meguro-Horike M, Kojima K, Kiyoi H, Sugiyama H, Nagase H, Tajima A, Hirao A.
- Journal Title
  
  Cell Death Disease
  
  Volume: 14 Issue: 9 Pages: 642-642
- DOI
  10.1038/s41419-023-06168-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-23K14729, KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K08448, KAKENHI-PROJECT-23K06629, KAKENHI-PROJECT-23K06672, KAKENHI-PROJECT-23K07855, KAKENHI-PUBLICLY-22H05622, KAKENHI-PROJECT-23K27437, KAKENHI-PROJECT-23K27624
[Journal Article] Real-world data of MDS and CMML in Japan: results of JALSG clinical observational study-11 (JALSG-CS-11)2023
- Author(s)
  Usuki Kensuke、Ohtake Shigeki、Honda Sumihisa、Kojima Kensuke、Kiyoi Hitoshi、et al
- Journal Title
  
  International Journal of Hematology
  
  Volume: 119 Issue: 2 Pages: 130-145
- DOI
  10.1007/s12185-023-03686-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-22K08518, KAKENHI-PROJECT-23K27624
[Journal Article] EBF1-JAK2 inhibits the PAX5 function through physical interaction with PAX5 and kinase activity.2023
- Author(s)
  Kojima Y, Kawashima F, Yasuda T, et al.
- Journal Title
  
  Int J Hematol.
  
  Volume: in press Issue: 1 Pages: 65-74
- DOI
  10.1007/s12185-023-03585-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24362, KAKENHI-PROJECT-23K15298, KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-23K27624
[Journal Article] Real-world data of AML in Japan: results of JALSG clinical observational study-11 (JALSG-CS-11)2023
- Author(s)
  Usuki Kensuke、Ohtake Shigeki、Honda Sumihisa、Kojima Kensuke、Miyazaki Yasushi、et al
- Journal Title
  
  International Journal of Hematology
  
  Volume: 119 Issue: 1 Pages: 24-38
- DOI
  10.1007/s12185-023-03677-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-22K08518, KAKENHI-PROJECT-23K27624
[Journal Article] Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts2023
- Author(s)
  Takagi Erina、Terakura Seitaro、Fujigaki Hidetsugu、Okamoto Akinao、Miyao Kotaro、Sawa Masashi、Morishita Takanobu、Goto Tatsunori、Ozawa Yukiyasu、Nishida Tetsuya、Fukushima Nobuaki、Ozeki Kazutaka、Hanajiri Ryo、Saito Kuniaki、Murata Makoto、Tomita Akihiro、Kiyoi Hitoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 4 Pages: 462-471
- DOI
  10.1007/s12185-023-03648-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15323, KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-22K08501, KAKENHI-PROJECT-21K08387, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-23K27624, KAKENHI-PROJECT-23K27843
[Journal Article] Clinicopathological characteristics associated with the engraftment of patient lymphoma cells in NOG mice2023
- Author(s)
  Sahashi Satomi、Shimada Kazuyuki、Takagi Yusuke、Aoki Tomohiro、Kunou Shunsuke、Sakamoto Akihiko、Murase Atsushi、Furukawa Katsuya、Kagaya Yusuke、Yamaga Yusuke、Takai Mika、Tokuyama Kiyonobu、Shimada Satoko、Nakamura Shigeo、Kiyoi Hitoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 2 Pages: 221-230
- DOI
  10.1007/s12185-023-03604-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07810, KAKENHI-PROJECT-23K27624
[Journal Article] Autologous peripheral blood stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia is safe but poses challenges for long-term maintenance of molecular remission: Results of the Auto-Ph17 study2023
- Author(s)
  Nishiwaki S, Sugiura I, Sato T, Kobayashi M, Osaki M, Sawa M, Adachi Y, Okabe M, Saito S, Morishita T, Kohno A, Nishiyama T, Iida H, Kurahashi S, Kuwatsuka Y, Sugiyama D, Ito S, Nishikawa H, Kiyoi H
- Journal Title
  
  eJHaem
  
  Volume: - Issue: 2 Pages: 358-369
- DOI
  10.1002/jha2.677
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08730, KAKENHI-PROJECT-22H00455, KAKENHI-PROJECT-23K27624
[Journal Article] Higher FVIII:C Measured by Chromogenic Substrate Assay Than by One-Stage Assay Is Associated With Silent Hemophilic Arthropathy2020
- Author(s)
  Mika Ogawa, Nobuaki Suzuki, Nobunori Takahashi, Shogo Tamura, Atsuo Suzuki, Sachiko Suzuki, Yuua Hattori, Misaki Kakihara, Takeshi Kanematsu, Toshihisa Kojima, Akira Katsumi, Fumihiko Hayakawa, Tetsuhito Kojima, Naoki Ishiguro , Hitoshi Kiyoi , Tadashi Matsushita
- Journal Title
  
  Thromb Res
  
  Volume: 188 Pages: 103-105
- DOI
  10.1016/j.thromres.2020.01.003
- NAID
  120006872431
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-17K09902, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K19910, KAKENHI-PROJECT-20K08711, KAKENHI-PROJECT-18H02835
[Journal Article] JSH Practical Guidelines for Hematological Malignancies, 2018: I. Leukemia-1. Acute myeloid leukemia (AML).2020
- Author(s)
  Kiyoi H, Yamaguchi H, Maeda Y, Yamauchi T
- Journal Title
  
  Int J Hematol
  
  Volume: 111 Issue: 5 Pages: 595-613
- DOI
  10.1007/s12185-020-02856-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K07294
[Journal Article] Prospective evaluation of prognostic impact of KIT mutations on acute myeloid leukemia with RUNX1-RUNX1T1 and CBFB-MYH112020
- Author(s)
  Ishikawa Y、Kawashima N、Atsuta Y、Sugiura I、Sawa M、Dobashi N、Yokoyama H、Doki N、Tomita A、Kiguchi T、Koh S、Kanamori H、Iriyama N、Kohno A、Moriuchi Y、Asada N、Hirano D、Togitani K、Sakura T、Hagihara M、Tomikawa T、Yokoyama Y、Asou N、Ohtake S、Matsumura I、Miyazaki Y、Naoe T、Kiyoi H
- Journal Title
  
  Blood Advances
  
  Volume: 4 Issue: 1 Pages: 66-75
- DOI
  10.1182/bloodadvances.2019000709
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23912, KAKENHI-PROJECT-17K09921
[Journal Article] Successful Introduction of Peritoneal Dialysis in an End-stage Renal Failure Patient with Idiopathic Aplastic Anemia2020
- Author(s)
  Suzuki Yasuhiro、Mizuno Masashi、Sakata Fumiko、Kojima Hiroshi、Sato Yuka、Kishimoto Mayuko、Suzuki Nobuaki、Kinashi Hiroshi、Saito Shoji、Katsuno Takayuki、Kosugi Tomoki、Maruyama Shoichi、Murata Makoto、Kiyoi Hitoshi、Ito Yasuhiko
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 5 Pages: 683-687
- DOI
  10.2169/internalmedicine.3775-19
- NAID
  130007804622
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-03-01
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08206, KAKENHI-PROJECT-17K09921
[Journal Article] Phase 1b/2 study of blinatumomab in Japanese adults with relapsed/refractory acute lymphoblastic leukemia2020
- Author(s)
  Kiyoi Hitoshi、Morris Joan D、Oh Iekuni、Maeda Yoshinobu、Minami Hironobu、Miyamoto Toshihiro、Sakura Toru、Iida Hiroatsu、Tuglus Catherine A、Chen Yuqi、Dos Santos Cedric、Kalabus James、Anderson Abraham、Hata Tomoko、Nakashima Yasuhiro、Kobayashi Yukio
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 4 Pages: 1314-1323
- DOI
  10.1111/cas.14322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921
[Journal Article] Anti-thyroid antibodies and thyroid echo pattern at baseline as risk factors for thyroid dysfunction induced by anti-programmed cell death-1 antibodies: a prospective study2020
- Author(s)
  Okada Norio、Iwama Shintaro、Kiyoi Hitoshi、Gotoh Momokazu、Ando Yuichi、Akiyama Masashi、Hasegawa Yoshinori、Arima Hiroshi
- Journal Title
  
  British Journal of Cancer
  
  Volume: 122 Issue: 6 Pages: 771-777
- DOI
  10.1038/s41416-020-0736-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-19K08976
[Journal Article] Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): a multicentre, single-arm, phase 2 trial2020
- Author(s)
  Shimada K, Yamaguchi M, Atsuta Y, Kiyoi H, Suzuki R, Tokunaga T, Nakamura S, Kinoshita T
- Journal Title
  
  The Lancet Oncology
  
  Volume: 21 Issue: 4 Pages: 593-602
- DOI
  10.1016/s1470-2045(20)30059-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09922
[Journal Article] FLT3 mutations in acute myeloid leukemia: Therapeutic paradigm beyond inhibitor development2019
- Author(s)
  Kiyoi Hitoshi、Kawashima Naomi、Ishikawa Yuichi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 2 Pages: 312-322
- DOI
  10.1111/cas.14274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23912, KAKENHI-PROJECT-17K09921
[Journal Article] Chromosomal translocation-mediated evasion from miRNA induces strong MEF2D fusion protein expression, causing inhibition of PAX5 transcriptional activity.2019
- Author(s)
  Hirano D, Hayakawa F, Yasuda T, Tange N, Yamamoto H, Kojima Y, Morishita T, Imoto N, Tsuzuki S, Mano H, Naoe T, Kiyoi H.
- Journal Title
  
  Oncogene
  
  Volume: 38 Issue: 13 Pages: 2263-2274
- DOI
  10.1038/s41388-018-0573-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K16103, KAKENHI-PROJECT-18H02645, KAKENHI-PROJECT-18H02835
[Journal Article] Clinical significance of ASXL2 and ZBTB7A mutations and C-terminally truncated RUNX1-RUNX1T1 expression in AML patients with t(8;21) enrolled in the JALSG AML201 study.2019
- Author(s)
  Kawashima N, Akashi A, Nagata Y, Kihara R, Ishikawa Y, Asou N, Ohtake S, Miyawaki S, Sakura T, Ozawa Y, Usui N, Kanamori H, Ito Y, Imai K, Suehiro Y, Kitamura K, Sakaida E, Takeshita A, Suzushima H, Naoe T, Matsumura I, Miyazaki Y, Ogawa S, Kiyoi H
- Journal Title
  
  Ann Hematol
  
  Volume: 98 Issue: 1 Pages: 83-91
- DOI
  10.1007/s00277-018-3492-5
- NAID
  120006623799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-16K08933, KAKENHI-PROJECT-16K09843, KAKENHI-PROJECT-19K07935
[Journal Article] Successful Perioperative Combination of High-Dose FVIII Therapy Followed by Emicizumab in a Patient with Hemophilia A with Inhibitors2019
- Author(s)
  Okamoto Shuichi、Suzuki Nobuaki、Suzuki Atsuo、Suzuki Sachiko、Tamura Shogo、Suzuki Mochihito、Takahashi Nobunori、Kojima Toshihisa、Kanematsu Takeshi、Kojima Tetsuhito、Kiyoi Hitoshi、Ishiguro Naoki、Matsushita Tadashi
- Journal Title
  
  TH Open
  
  Volume: 03 Issue: 04 Pages: e364-e366
- DOI
  10.1055/s-0039-3401001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-17K09902, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K19910
[Journal Article] Tamibarotene maintenance improved relapse-free survival of acute promyelocytic leukemia: a final result of prospective, randomized, JALSG-APL204 study.2019
- Author(s)
  Takeshita A, Asou N, Atsuta Y, Sakura T, Ueda Y, Sawa M, Dobashi N, Taniguchi Y, Suzuki R, Nakagawa M, Tamaki S, Hagihara M, Fujimaki K, Furumaki H, Obata Y, Fujita H, Yanada M, Maeda Y, Usui N, Kobayashi Y, Kiyoi H, Ohtake S, Matsumura I, Naoe T, Miyazaki Y
- Journal Title
  
  Leukemia
  
  Volume: 33 Issue: 2 Pages: 358-370
- DOI
  10.1038/s41375-018-0233-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-16K08933, KAKENHI-PROJECT-16K09843, KAKENHI-PROJECT-18K08375, KAKENHI-PROJECT-19K07935
[Journal Article] Quantitative Assessment of T Cell Clonotypes in Human Acute Graft-versus-Host Disease Tissues.2019
- Author(s)
  Koyama D, Murata M, Hanajiri R, Akashi T, Okuno S, Kamoshita S, Julamanee J, Takagi E, Miyao K, Sakemura R, Goto T, Terakura S, Nishida T, Kiyoi H
- Journal Title
  
  Biol Blood Marrow Transplant
  
  Volume: 25 Issue: 3 Pages: 417-423
- DOI
  10.1016/j.bbmt.2018.10.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K08321, KAKENHI-PROJECT-18K08351
[Journal Article] ZNF384-fusion proteins have high affinity for the transcriptional coactivator EP300 and aberrant transcriptional activities.2019
- Author(s)
  3.Yamamoto H, Hayakawa F, Yasuda T, Odaira K, Minamikawa Y, Tange N, Hirano D,Kojima Y, Morishita T, Tsuzuki S, Naoe T, Kiyoi H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 593 Issue: 16 Pages: 2151-2161
- DOI
  10.1002/1873-3468.13506
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K16103
[Journal Article] Defective Epstein-Barr virus in chronic active infection and haematological malignancy.2019
- Author(s)
  Okuno Y, Murata T, Sato Y,Yoshida K, Sawada A, Inoue M, Kawa K, Seto M, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Nishida T, Kiyoi H, Kato S, Nakamura S, Morishima S, Yoshikawa T, Fujiwara S, Shimizu N, Isobe Y, Noguchi M, Kikuta A, Iwatsuki K, Takahashi Y, Kojima S, Ogawa S, Kimura H.
- Journal Title
  
  Nat Microbiol.
  
  Volume: 4 Issue: 3 Pages: 404-413
- DOI
  10.1038/s41564-018-0334-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09934, KAKENHI-PROJECT-17K10107, KAKENHI-PROJECT-18K07816, KAKENHI-PROJECT-18K15165, KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-17H04081
[Journal Article] Pyruvate secreted from patient-derived cancer-associated fibroblasts supports survival of primary lymphoma cells.2019
- Author(s)
  Sakamoto A, Kunou S, Shimada K, Tsunoda M, Aoki T, Iriyama C, Tomita A, Nakamura S, Hayakawa F, Kiyoi H.
- Journal Title
  
  Cancer Sci
  
  Volume: 110 Issue: 1 Pages: 269-278
- DOI
  10.1111/cas.13873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09922, KAKENHI-PROJECT-18H02835
[Journal Article] Patients With Antithyroid Antibodies Are Prone To Develop Destructive Thyroiditis by Nivolumab: A Prospective Study2018
- Author(s)
  Kobayashi Tomoko、Iwama Shintaro、Yasuda Yoshinori、Okada Norio、Tsunekawa Taku、Onoue Takeshi、Takagi Hiroshi、Hagiwara Daisuke、Ito Yoshihiro、Morishita Yoshiaki、Goto Motomitsu、Suga Hidetaka、Banno Ryoichi、Yokota Kenji、Hase Tetsunari、Morise Masahiro、Hashimoto Naozumi、Ando Masahiko、Kiyoi Hitoshi、et al.
- Journal Title
  
  J Endocr Soc.
  
  Volume: 2 Issue: 3 Pages: 241-251
- DOI
  10.1210/js.2017-00432
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-16K19552
[Journal Article] Impact of hospital length of stay on the risk of readmission and overall survival after allogeneic stem cell transplantation.2018
- Author(s)
  Seto A, Atsuta Y, Kawashima N, Ozawa Y, Miyamura K, Kiyoi H
- Journal Title
  
  Int J Hematol
  
  Volume: 108 Issue: 3 Pages: 290-297
- DOI
  10.1007/s12185-018-2477-4
- NAID
  120006536923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921
[Journal Article] Transcriptional activities of DUX4 fusions in B-cell acute lymphoblastic leukemia2018
- Author(s)
  Tanaka Yosuke、Kawazu Masahito、Yasuda Takahiko、Tamura Miki、Hayakawa Fumihiko、Kojima Shinya、Ueno Toshihide、Kiyoi Hitoshi、Naoe Tomoki、Mano Hiroyuki
- Journal Title
  
  Haematologica
  
  Volume: 103 Issue: 11 Pages: 522-526
- DOI
  10.3324/haematol.2017.183152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K16103, KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-17J10130
[Journal Article] Introduction of Genetically-Modified CD3ζ Improves Proliferation and Persistence of Antigen-specific CTLs.2018
- Author(s)
  Miyao K, Terakura S, Okuno S, Julamanee J, Watanabe K, Hamana H, Kishi H, Sakemura R, Koyama D, Goto T, Nishida T, Murata M, Kiyoi H
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 6 Pages: 733-744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921
[Journal Article] Identification of the novel deletion-type PML-RARA mutation associated with the retinoic acid resistance in acute promyelocytic leukemia.2018
- Author(s)
  Hattori H, Ishikawa Y, Kawashima N, Akashi A, Yamaguchi Y, Harada Y, Hirano D, Adachi Y, Miyao K, Ushijima Y, Terakura S, Nishida T, Matsushita T, Kiyoi H
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 10 Pages: e0204850-e0204850
- DOI
  10.1371/journal.pone.0204850
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K08351
[Journal Article] Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases.2018
- Author(s)
  Li JF, Dai YT, Kubota Y, Kiyoi H, Matsumura I, Miyazaki Y, Olsson L, Tan AM, Ariffin H, Chen J, Takita J, Yasuda T, Mano H, Johansson B, Yang JJ, Yeoh AE, Hayakawa F, Chen Z, Pui CH, Fioretos T, Chen SJ, Huang JY.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 115 Issue: 50
- DOI
  10.1073/pnas.1814397115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K19467, KAKENHI-PROJECT-18K16103, KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-18H02835
[Journal Article] Mutation analysis of therapy-related myeloid neoplasms2018
- Author(s)
  Nishiyama Takahiro、Ishikawa Yuichi、Kawashima Naomi、Akashi Akimi、Adachi Yoshiya、Hattori Hikaru、Ushijima Yoko、Kiyoi Hitoshi
- Journal Title
  
  Cancer Genetics
  
  Volume: 222 Pages: 38-45
- DOI
  10.1016/j.cancergen.2018.02.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921
[Journal Article] Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response.2018
- Author(s)
  Ueda N, Uemura Y, Zhang R, Kitayama S, Iriguchi S, Kawai Y, Yasui Y, Tatsumi M, Ueda T, Liu TY, Mizoro Y, Okada C, Watanabe A, Nakanishi M, Senju S, Nishimura Y, Kuzushima K, Kiyoi H, Naoe T, Kaneko S
- Journal Title
  
  Stem Cell Reports
  
  Volume: 10 Issue: 6 Pages: 1935-1946
- DOI
  10.1016/j.stemcr.2018.04.025
- NAID
  120006473765
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K10717, KAKENHI-PROJECT-17K10806, KAKENHI-PROJECT-17KT0108, KAKENHI-PLANNED-16H06498, KAKENHI-PROJECT-16H05194, KAKENHI-PROJECT-17K07238, KAKENHI-PROJECT-18H02641, KAKENHI-PROJECT-18H02826
[Journal Article] Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study2018
- Author(s)
  Harada Y、Nagata Y、Kihara R、Ishikawa Y、Asou N、Ohtake S、Miyawaki S、Sakura T、Ozawa Y、Usui N、Kanamori H、Ito Y、Imai K、Suehiro Y、Kobayashi S、Kitamura K、Sakaida E、Onizuka M、Takeshita A、Ishida F、Suzushima H、Ishizawa K、Naoe T、Matsumura I、Miyazaki Y、Ogawa S、Kiyoi H
- Journal Title
  
  Leukemia Research
  
  Volume: 66 Pages: 20-27
- DOI
  10.1016/j.leukres.2018.01.008
- NAID
  120006473597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09843, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-15K08609, KAKENHI-PROJECT-18K08375
[Journal Article] Final analysis of the JALSG Ph+ALL202 study: tyrosine kinase inhibitor-combined chemotherapy for Ph+ALL2018
- Author(s)
  Hatta Y, Mizuta S, Matsuo K, Ohtake S, Iwanaga M, Sugiura I, Doki N, Kanamori H, Ueda Y, Yoshida C, Dobashi N, Maeda T, Yujiri T, Monma F, Ito Y, Hayakawa F, Takeuchi J, Kiyoi H, Miyazaki Y, Naoe T
- Journal Title
  
  Ann Hematol
  
  Volume: 97 Issue: 9 Pages: 1535-1545
- DOI
  10.1007/s00277-018-3323-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K08358, KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-18H02835
[Journal Article] Exome analysis of treatment-related AML after APL suggests secondary evolution2018
- Author(s)
  Wang Tianjiao、Jacoby Meagan A.、Duncavage Eric J.、Miller Christopher A.、Heath Sharon、Rahme Ramy、Fenaux Pierre、Ades Lionel、Renneville Aline、Cassinat Bruno、Takeshita Akihiro、Asou Norio、Miyazaki Yasushi、Kiyoi Hitoshi、Ravandi Farhad、Westervelt Peter、Wartman Lukas D.、Welch John S.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 印刷中 Issue: 5 Pages: 984-987
- DOI
  10.1111/bjh.15681
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-19K07935, KAKENHI-PROJECT-17K09921
[Journal Article] Distinct gene alterations with a high percentage of myeloperoxidase-positive leukemic blasts in de novo acute myeloid leukemia2018
- Author(s)
  Kamijo Rena、Itonaga Hidehiro、Kihara Rika、Nagata Yasunobu、Hata Tomoko、Asou Norio、Ohtake Shigeki、Shiraishi Yuichi、Chiba Kenichi、Tanaka Hiroko、Miyano Satoru、Ogawa Seishi、Naoe Tomoki、Kiyoi Hitoshi、Miyazaki Yasushi
- Journal Title
  
  Leukemia Research
  
  Volume: 65 Pages: 34-41
- DOI
  10.1016/j.leukres.2017.12.006
- NAID
  120006988058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09843, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-17K16189, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308
[Journal Article] Clinical effectiveness of geriatric assessment for predicting the tolerability of outpatient chemotherapy in older adults with cancer2018
- Author(s)
  Hayashi Naomi、Matsuoka Ayumu、Goto Hidemi、Gotoh Momokazu、Kiyoi Hitoshi、Kodera Yasuhiro、Nagino Masato、Nagashima Fumio、Ando Yuichi
- Journal Title
  
  J Geriatr Oncol
  
  Volume: 9 Issue: 1 Pages: 84-86
- DOI
  10.1016/j.jgo.2017.07.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921
[Journal Article] Biology and management of primary effusion lymphoma.2018
- Author(s)
  Shimada K, Hayakawa F, Kiyoi H
- Journal Title
  
  Blood
  
  Volume: 132 Issue: 18 Pages: 1879-1888
- DOI
  10.1182/blood-2018-03-791426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09922, KAKENHI-PROJECT-18H02835
[Journal Article] Analysis of the oligomeric states of nucleophosmin using size exclusion chromatography.2018
- Author(s)
  Sakashita G, Kiyoi H, Naoe T, Urano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 4008-4008
- DOI
  10.1038/s41598-018-22359-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-17K09921
[Journal Article] Underweight status at diagnosis is associated with poorer outcomes in adult patients with acute myeloid leukemia: a retrospective study of JALSG AML 2012017
- Author(s)
  Harada Kaito、Doki Noriko、Hagino Takeshi、Miyawaki Shuichi、Ohtake Shigeki、Kiyoi Hitoshi、Miyazaki Yasushi、Fujita Hiroyuki、Usui Noriko、Okumura Hirokazu、Miyamura Koichi、Nakaseko Chiaki、Fujieda Atsushi、Nagai Tadashi、Yamane Takahisa、Sakamaki Hisashi、Ohnishi Kazunori、Naoe Tomoki、Ohno Ryuzo、Ohashi Kazuteru
- Journal Title
  
  Annals of Hematology
  
  Volume: 97 Issue: 1 Pages: 73-81
- DOI
  10.1007/s00277-017-3156-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09843, KAKENHI-PROJECT-17K09921
[Journal Article] Impact of T-cell chimerism on relapse after cord blood transplantation for hematological malignancies: Nagoya Blood and Marrow Transplantation Group study2017
- Author(s)
  Yokohata E, Kuwatsuka Y, Ohashi H, Terakura S, Kawashima N, Seto A, Kurahashi S, Ozawa Y, Goto T, Imahashi N, Nishida T, Miyao K, Sakemura R, Kato T, Sawa M, Kohno A, Sao H, Iida H, Kiyoi H, Naoe T, Miyamura K, Murata M
- Journal Title
  
  Bone Marrow Transplant.
  
  Volume: in press Issue: 4 Pages: 612-614
- DOI
  10.1038/bmt.2016.323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06868, KAKENHI-PROJECT-26860346, KAKENHI-PROJECT-15K09498, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-15K09497
[Journal Article] A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells withFLT3mutations2017
- Author(s)
  Yamaura Takeshi、Nakatani Toshiyuki、Uda Ken、Ogura Hayato、Shin Wigyon、Kurokawa Naoya、Saito Koichi、Fujikawa Norie、Date Tomomi、Takasaki Masaru、Terada Daisuke、Hirai Atsushi、Akashi Akimi、Chen Fangli、Adachi Yoshiya、Ishikawa Yuichi、Hayakawa Fumihiko、Hagiwara Shinji、Naoe Tomoki、Kiyoi Hitoshi
- Journal Title
  
  Blood
  
  Volume: 131 Issue: 4 Pages: 426-438
- DOI
  10.1182/blood-2017-05-786657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921
[Journal Article] High incidence of extensive chronic graft-versus-host disease in patients with the REG3A rs7588571 non-GG genotype2017
- Author(s)
  Koyama Daisuke、Murata Makoto、Hanajiri Ryo、Okuno Shingo、Kamoshita Sonoko、Julamanee Jakrawadee、Takagi Erina、Hirano Daiki、Miyao Kotaro、Sakemura Reona、Goto Tatsunori、Hayakawa Fumihiko、Seto Aika、Ozawa Yukiyasu、Miyamura Koichi、Terakura Seitaro、Nishida Tetsuya、Kiyoi Hitoshi
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 9 Pages: e0185213-e0185213
- DOI
  10.1371/journal.pone.0185213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-16H06868, KAKENHI-PROJECT-15K09497, KAKENHI-PROJECT-15K09498
[Journal Article] A nationwide survey of hypoplastic myelodysplastic syndrome (a multicenter retrospective study)2017
- Author(s)
  Kobayashi T, Nannya Y, Ichikawa M, Oritani K, Kanakura Y, Tomita A, Kiyoi H, Kobune M, Kato J, Kawabata H, Shindo M, Torimoto Y, Yonemura Y, Tohyama K, et al
- Journal Title
  
  American Journal of Hematology
  
  Volume: 92 Issue: 12 Pages: 1324-1332
- DOI
  10.1002/ajh.24905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09026, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09923, KAKENHI-PROJECT-15K09473, KAKENHI-PUBLICLY-16H01196, KAKENHI-PROJECT-15K09480
[Journal Article] Deeper molecular response is a predictive factor for treatment-free remission after imatinib discontinuation in patients with chronic phase chronic myeloid leukemia: the JALSG-STIM213 study2017
- Author(s)
  Takahashi Naoto、Miyata Yasuhiko、Kobayashi Shinichi、Usuki Kensuke、Matsumura Itaru、Minami Yosuke、Usui Noriko、Fukuda Tetsuya、Kobayashi Yukio、Kiyoi Hitoshi、et al.
- Journal Title
  
  Int J Hematol
  
  Volume: 107 Issue: 2 Pages: 185-193
- DOI
  10.1007/s12185-017-2334-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-15K09461, KAKENHI-PROJECT-18K08375, KAKENHI-PROJECT-16K09865
[Journal Article] Phase II study of intrabone single unit cord blood transplantation for hematological malignancies2017
- Author(s)
  Murata Makoto、Maeda Yoshinobu、Masuko Masayoshi、et.al
- Journal Title
  
  Cancer Science
  
  Volume: 108 Issue: 8 Pages: 1634-1639
- DOI
  10.1111/cas.13291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-17K09006, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-16H06868, KAKENHI-PROJECT-15K09497, KAKENHI-PROJECT-15K09498
[Journal Article] Frequent somatic mutations in epigenetic regulators in newly diagnosed chronic myeloid leukemia.2017
- Author(s)
  Togasaki E, Takeda J, Yoshida K, Shiozawa Y, Takeuchi M, Kiyoi H, Ohnishi K, Ohtake S, Asou N, Kobayashi Y, Miyazaki Y, Miyano S, Ogawa S, Matsumura I, Nakaseko C, Naoe T.
- Journal Title
  
  Blood Cancer J.
  
  Volume: 7 Issue: 4 Pages: 2017-2017
- DOI
  10.1038/bcj.2017.36
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461431, KAKENHI-PROJECT-16K09862, KAKENHI-PROJECT-16K09865, KAKENHI-PROJECT-17K09921, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16K08933
[Journal Article] Altered EZH2 splicing and expression is associated with impaired histone H3 lysine 27 tri-Methylation in myelodysplastic syndrome2017
- Author(s)
  Shirahata-Adachi Mizuho、Iriyama Chisako、Tomita Akihiro、Suzuki Yasuhiro、Shimada Kazuyuki、Kiyoi Hitoshi
- Journal Title
  
  Leuk Res
  
  Volume: 63 Pages: 90-97
- DOI
  10.1016/j.leukres.2017.10.015
- NAID
  120006473525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09922, KAKENHI-PROJECT-15K09473
[Journal Article] YM155 induces apoptosis through proteasome-dependent degradation of MCL-1 in primary effusion lymphoma.2017
- Author(s)
  Kojima Y, Hayakawa F, Morishita T, Sugimoto K, Minamikawa Y, Iwase M, Yamamoto H, Hirano D, Imoto N, Shimada K, Okada S, Kiyoi H
- Journal Title
  
  Pharmacol Res.
  
  Volume: in press Pages: 242-251
- DOI
  10.1016/j.phrs.2017.04.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860724, KAKENHI-PROJECT-16K08742, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09922, KAKENHI-PROJECT-15K09472
[Journal Article] High-dose methotrexate therapy significantly improved survival of adult acute lymphoblastic leukemia: a phase III study by JALSG2017
- Author(s)
  Sakura T、Hayakawa F、Sugiura I、Murayama T、Imai K、Usui N、Fujisawa S、Yamauchi T、Yujiri T、Kakihana K、Ito Y、Kanamori H、Ueda Y、Miyata Y、Kurokawa M、Asou N、Ohnishi K、Ohtake S、Kobayashi Y、Matsuo K、Kiyoi H、Miyazaki Y、Naoe T
- Journal Title
  
  Leukemia
  
  Volume: 32 Issue: 3 Pages: 626-632
- DOI
  10.1038/leu.2017.283
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-15K09472, KAKENHI-PROJECT-18K08358, KAKENHI-PROJECT-16K09865
[Journal Article] Identification of volasertib-resistant mechanism and evaluation of combination effects with volasertib and other agents on acute myeloid leukemia2017
- Author(s)
  Adachi Yoshiya、Ishikawa Yuichi、Kiyoi Hitoshi
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 45 Pages: 78452-78465
- DOI
  10.18632/oncotarget.19632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921
[Journal Article] Prognostic value of genetic mutations in adolescent and young adults with acute myeloid leukemia2017
- Author(s)
  Kuwatsuka Y、Asou N、Ohtake S、Miyawaki S、Miyazaki Y、Sakura T、Ozawa Y、Usui N、Kanamori H、Ito Y、Imai K、Suehiro Y、Kobayashi S、Kitamura K、Sakaida E、Ogawa S、Naoe T、Hayashi Y、Horibe K、Manabe A、Mizutani S、Adachi S、Kiyoi H et al.
- Journal Title
  
  International Journal of Hematology
  
  Volume: 107 Issue: 2 Pages: 201-210
- DOI
  10.1007/s12185-017-2340-z
- NAID
  120006473552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09843, KAKENHI-PROJECT-17K08911, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-15K08654, KAKENHI-PROJECT-17H04110
[Journal Article] BLNK is a selective target of repression by PAX5-PML in the differentiation block that leads to the development of acute lymphoblastic leukemia.2016
- Author(s)
  Imoto N, Hayakawa F, Kurahashi S, Morishita T, Kojima Y, Yasuda T, Sugimoto K, Tsuzuki S, Naoe T, Kiyoi H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 9 Pages: 4723-31
- DOI
  10.1074/jbc.m115.637835
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09472, KAKENHI-PROJECT-15K09492, KAKENHI-PROJECT-25293218
[Journal Article] Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells2015
- Author(s)
  Sugimoto K, Hayakawa F, Shimada S, Morishita T, Shimada K, Katakai T, Tomita A, Kiyoi H, Naoe T
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 13054-13054
- DOI
  10.1038/srep13054
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09472, KAKENHI-PROJECT-15K09473, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-25670101, KAKENHI-PROJECT-25293218
[Journal Article] Target antigen density governs the efficacy of anti-CD20-CD28-CD3 ζ chimeric antigen receptor-modified effector CD8+ T cells.2015
- Author(s)
  Watanabe K, Terakura S, Martens AC, van Meerten T, Uchiyama S, Imai M, Sakemura R, Goto T, Hanajiri R, Imahashi N, Shimada K, Tomita A, Kiyoi H, Nishida T, Naoe T, Murata M.
- Journal Title
  
  J Immunol.
  
  Volume: 194(3) Issue: 3 Pages: 911-20
- DOI
  10.4049/jimmunol.1402346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591388, KAKENHI-PROJECT-24790969
[Journal Article] Target Antigen Density Governs the Efficacy of Anti-CD20-CD28-CD3 ζ Chimeric Antigen Receptor-Modified Effector CD8+ T Cells.2015
- Author(s)
  Watanabe K, Terakura S, Martens AC, van Meerten T, Uchiyama S, Imai M, Sakemura R, Goto T, Hanajiri R, Imahashi N, Shimada K, Tomita A, Kiyoi H, Nishida T, Naoe T, Murata M
- Journal Title
  
  J Immunol
  
  Volume: 194(3) Pages: 911-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293218
[Journal Article] FLT3 INHIBITORS: RECENT ADVANCES AND PROBLEMS FOR CLINICAL APPLICATION.2015
- Author(s)
  Kiyoi H.
- Journal Title
  
  Nagoya J Med Sci.
  
  Volume: 77 Pages: 7-17
- NAID
  120005549547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591387
[Journal Article] Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients2014
- Author(s)
  Kihara R, S. Ogawa, S. (32/33) Naoe, T.
- Journal Title
  
  Leukemia
  
  Volume: inpress Issue: 8 Pages: 1586-95
- DOI
  10.1038/leu.2014.55
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134006, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-24590688, KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-25293218, KAKENHI-PROJECT-26461431
[Journal Article] Markedly improved outcomes and acceptable toxicity in adolescents and young adults with acute lymphoblastic leukemia following treatment with a pediatric protocol: a phase II study by the Japan Adult Leukemia Study Group.2014
- Author(s)
  Hayakawa F, Sakura T, Yujiri T, Kondo E, Fujimaki K, Sasaki O, Miyatake J, Handa H, Ueda Y, Aoyama Y, Takada S, Tanaka Y, Usui N, Miyawaki S, Suenobu S, Horibe K, Kiyoi H, Ohnishi K, Miyazaki Y, Ohtake S, Kobayashi Y, Matsuo K, Naoe T; Japan Adult Leukemia Study Group (JALSG).
- Journal Title
  
  Blood Cancer J
  
  Volume: 4
- NAID
  120006987091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293218
[Journal Article] Efficacy of ofatumumab against rituximab-resistant B-CLL/SLL cells with low CD20 protein expression.2014
- Author(s)
  Shimada K, Tomita A, Saito S, Kiyoi H.
- Journal Title
  
  Br J Haematol
  
  Volume: 165 Issue: 3 Pages: 455-7
- DOI
  10.1111/bjh.12857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-24591388, KAKENHI-PROJECT-25293218, KAKENHI-PROJECT-25670449
[Journal Article] Expression of CD56 is an unfavorable prognostic factor for acute promyelocytic leukemia with higher initial white blood cell counts.2014
- Author(s)
  Ono T, Takeshita A, Kishimoto Y, Kiyoi H, Okada M, Yamauchi T, Emi N, Horikawa K, Matsuda M, Shinagawa K, Monma F, Ohtake S, Nakaseko C, Takahashi M, Kimura Y, Iwanaga M, Asou N, Naoe T; Japan Adult Leukemia Study Group.
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Issue: 1 Pages: 97-104
- DOI
  10.1111/cas.12319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23501307, KAKENHI-PROJECT-23591396, KAKENHI-PROJECT-24501340, KAKENHI-PROJECT-24590688, KAKENHI-PROJECT-24591387
[Journal Article] De novo diffuse large B-cell lymphoma with a CD20 immunohistochemistry-positive and flow cytometry-negative phenotype: Molecular mechanisms and correlation with rituximab sensitivity.2014
- Author(s)
  Tokunaga T, Tomita A, Sugimoto K, Shimada K, Iriyama C, Hirose T, Shirahata-Adachi M, Suzuki Y, Mizuno H, Kiyoi H, Asano N, Nakamura S, Kinoshita T, Naoe T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Issue: 1 Pages: 35-43
- DOI
  10.1111/cas.12307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-24591388, KAKENHI-PROJECT-25670449
[Journal Article] Leukemic evolution of donor-derived cells harboring IDH2 and DNMT3A mutations after allogeneic stem cell transplantation.2014
- Author(s)
  Yasuda T, Ueno T, Fukumura K, Yamato A, Ando M, Yamaguchi H, Soda M, Kawazu M, Sai E, Yamashita Y, Murata M, Kiyoi H, Naoe T, Mano H.
- Journal Title
  
  Leukemia
  
  Volume: 28 Issue: 2 Pages: 426-428
- DOI
  10.1038/leu.2013.278
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591415, KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-26461155
[Journal Article] Role of hematopoietic stem cell transplantation for relapsed acute promyelocytic leukemia: a retrospective analysis of JALSG-APL97.2013
- Author(s)
  Fujita H, Asou N, Iwanaga M, Hyo R, Nomura S, Kiyoi H, Okada M, Inaguma Y, Matsuda M, Yamauchi T, Ohtake S, Izumi T, Nakaseko C, Ishigatsubo Y, Shinagawa K, Takeshita A, Miyazaki Y, Ohnishi K, Miyawaki S, Naoe T; Japan Adult Leukemia Study Group.
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Issue: 10 Pages: 1339-1345
- DOI
  10.1111/cas.12230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501307, KAKENHI-PROJECT-23590694, KAKENHI-PROJECT-23591379, KAKENHI-PROJECT-23591396, KAKENHI-PROJECT-24590688, KAKENHI-PROJECT-24591387
[Journal Article] Mechanisms of action and resistance to all-trans retinoic acid (ATRA) and arsenic trioxide (As2O 3) in acute promyelocytic leukemia.2013
- Author(s)
  Tomita A, Kiyoi H, Naoe T.
- Journal Title
  
  Int J Hematol
  
  Volume: 97 Issue: 6 Pages: 717-725
- DOI
  10.1007/s12185-013-1354-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-24591388
[Journal Article] GATA2 zincfinger2mutationfoundinacutemyeloidleukemia impairs myeloiddifferentiation2013
- Author(s)
  Keiko Niimi, Hitoshi Kiyoi, Yuichi Ishikawa, Fumihiko Hayakawa, Shingo Kurahashi, Rika Kihara, Akihiro Tomita, Tomoki Naoe
- Journal Title
  
  Leukemia ResearchReports
  
  Volume: 2 Issue: 1 Pages: 21-25
- DOI
  10.1016/j.lrr.2013.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591381, KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-24591388, KAKENHI-PUBLICLY-25118711
[Journal Article] The demarcation between younger and older acute myeloid leukemia patients.2013
- Author(s)
  Yanada M, Ohtake S, Miyawaki S, Sakamaki H, Sakura T, Maeda T, Miyamura K, Asou N, Oh I, Miyatake J, Kanbayashi H, Takeuchi J, Takahashi M, Dobashi N, Kiyoi H, Miyazaki Y, Emi N, Kobayashi Y, Ohno R, Naoe T.
- Journal Title
  
  Cancer
  
  Volume: 119 Issue: 18 Pages: 3326-3333
- DOI
  10.1002/cncr.28212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591396, KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-25461442
[Journal Article] Mutations in the nucleolar phosphoprotein, nucleophosmin, promote the expression of the oncogenic transcription factor MEF/ELF4 in leukemia cells and potentiates transformation.2013
- Author(s)
  Ando K
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Issue: 13 Pages: 9457-9467
- DOI
  10.1074/jbc.m112.415703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591040, KAKENHI-PROJECT-22591065, KAKENHI-PROJECT-23590829, KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-25293218
[Journal Article] Chimeric antisense RNA derived from chromosomal translocation modulates target gene expression.2012
- Author(s)
  Takumi Sugimoto
- Journal Title
  
  Haematologica
  
  Volume: 97 Issue: 8 Pages: 1278-1280
- DOI
  10.3324/haematol.2011.057869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-24591388
[Journal Article] B cell receptor-ERK1/2 signal cancels PAX5-dependent repression of BLIMP1 through PAX5 phosphorylation: a mechanism of antigen-triggering plasma cell differentiation2012
- Author(s)
  Takahiko Yasuda, Fumihiko Hayakawa, Shingo Kurahashi, Keiki Sugimoto , Yosuke Minami, Akihiro Tomita, Tomoki Naoe
- Journal Title
  
  Journal of Immunology
  
  Volume: 188 Issue: 12 Pages: 6127-34
- DOI
  10.4049/jimmunol.1103039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591381, KAKENHI-PROJECT-23659487, KAKENHI-PROJECT-24591388
[Journal Article] Molecular lesions in childhood and adult acute megakaryoblastic leukaemia2012
- Author(s)
  Hama A, Muramatsu H, Makishima H, Sugimoto Y, Szpurka H, Jasek M, OKeefe C, Takahashi Y, Sakaguchi H, Doisaki S, Shimada A, Watanabe N, Kato K, Kiyoi H, Naoe T, Kojima S, Maciejewski JP.
- Journal Title
  
  Br J Haematol
  
  Volume: 156 Pages: 316-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Y654 ofβ-catenin is essential for FLT3/ITD-related tyrosine phosphorylation and nuclear localization ofβ-catenin Eur J Haematol2012
- Author(s)
  Kajiguchi T, Katsumi A, Tanizaki R, Kiyoi H, Naoe T.
- Volume
  (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Long-term outcome of imatinib therapy, with assessment of its dosage and blood levels, for chronic myelogenous leukemia2012
- Author(s)
  Ohnishi K, Nakaseko C, Takeuchi J, Fujisawa S, Nagai T, Yamazaki H, Tauchi T, Imai K, Mori N, Yagasaki F, Maeda Y, Usui N, Miyazaki Y, Miyamura K, Kiyoi H, Ohtake S, Naoe T.
- Journal Title
  
  Cancer Sci
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Using peripheral blood circulating DNA stodetect CpG global methylation status and genetic mutations in patients with myelo dysplastic syndrome2012
- Author(s)
  Iriyama C, Tomita A, Hoshino H, Shirahata M, Furukawa-Hibi Y, Yamada K, Kiyoi H, Naoe T.
- Journal Title
  
  Biochem Biophys Res Commun
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Prevalence and clinical characteristics of N-terminally truncated WT1 expression in acute myeloid leukemia2011
- Author(s)
  Ishikawa Y, Kiyoi H, Naoe T.
- Journal Title
  
  Leuk Res
  
  Volume: 35 Pages: 685-688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] FLT3/ITD regulate sleukaemia cell adhesion throughα4β1integrin and Pyk2 signaling2011
- Author(s)
  Katsumi A, Kiyoi H, Abe A, Tanizaki R, Iwasaki T, Kobayashi M, Matsushita T, Senga T, Kohno T, Kojima T, Kaibuchi K, Hamaguchi M, Naoe T.
- Journal Title
  
  Eur J Haematol
  
  Volume: 86 Pages: 191-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Randomized study of induction therapy comparing standard-dose idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia : JALSG AML201 Study2011
- Author(s)
  Ohtake S, Miyawaki S, Fujita H, Kiyoi H, Shinagawa K, Usui N, Okumura H, Miyamura K, Nakaseko C, Miyazaki Y, Fujieda A, Nagai T, Yamane T, Taniwaki M, Takahashi M, Yagasaki F, Kimura Y, Asou N, Sakamaki H, Handa H, Honda S, Ohnishi K, Naoe T, Ohno R.
- Journal Title
  
  Blood
  
  Volume: 117 Pages: 2358-2365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Anovel insertion mutation of K294RGG within BCR-ABL kinase domain confers imatinib-resistance : sequential analysis of the clonal evolution in a patient with chronic myeloid leukemia in blast crisis2011
- Author(s)
  Sakai K, Ishikawa Y, Mori Y, Kobayashi M, Iriyama C, Ozawa Y, Suzuki T, Minami Y, Ishikawa K, Kaneda N, Naoe T, Kiyoi H.
- Journal Title
  
  Int J Hematol
  
  Volume: 93 Pages: 237-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Japan Adult Leukemia Study Group. Phase Itrial of gemtuzumab ozogamicin in intensive combination chemotherapy for relapsed or refractory adult acute myeloid leukemia(AML): Japan Adult Leukemia Study Group(JALSG)-AML206 study2011
- Author(s)
  Usui N, Takeshita A, Nakaseko C, Dobashi N, Fujita H, Kiyoi H, Kobayashi Y, Sakura T, Yahagi Y, Shigeno K, Ohwada C, Miyazaki Y, Ohtake S, Miyawaki S, Naoe T, Ohnishi K.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 1358-1365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Missense mutations in PML-RARA are critical for the lack of responsiveness to arsenic trioxide treatment2011
- Author(s)
  Goto E, Tomita A, Hayakawa F, Atsumi A, Kiyoi H, Naoe T.
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 1600-1609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] A randomized comparison of four courses of standard-dose multiagent chemotherapy versus three courses of high-dose cytarabine alone in post-remission therapy for acute myeloid leukemia in adults : the JALSG AML201 study2011
- Author(s)
  Miyawaki S, Ohtake S, Fujisawa S, Kiyoi H, Shinagawa K, Usui N, Sakura T, Miyamura K, Nakaseko C, Miyazaki Y, Fujieda A, Nagai T, Yamane T, Taniwaki M, Takahashi M, Yagasaki F, Kimura Y, Asou N, Sakamaki H, Handa H, Honda S, Ohnishi K, Naoe T, Ohno R.
- Journal Title
  
  Blood
  
  Volume: 117 Pages: 2366-2372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Trough plasma concentration of imatinib reflects BCR-ABL kinase in hibitory activity and clinical response in chronic-phase chronic myeloid leukemia : a report from the BINGO study2010
- Author(s)
  Ishikawa Y, Kiyoi H, Watanabe K, Miyamura K, Nakano Y, Kitamura K, Kohno A, Sugiura I, Yokozawa T, Hanamura A, Yamamoto K, Iida H, Emi N, Suzuki R, Ohnishi K, Naoe T.
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 2186-2192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Phase I study of KW-0761, a defucosylated humanized anti-CCR4 antibody, in relapsed patients with adult T-cell leukemia-lymphoma and peripheral T-cell lymphoma2010
- Author(s)
  Yamamoto K, Utsunomiya A, Tobinai K, Tsukasaki K, Uike N, Uozumi K, Yamaguchi K, Yamada Y, Hanada S, Tamura K, Nakamura S, Inagaki H, Ohshima K, Kiyoi H, Ishida T, Matsushima K, Akinaga S, Ogura M, Tomonaga M, Ueda R.
- Journal Title
  
  J Clin Oncol
  
  Volume: 28 Pages: 1591-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Array-based genomic resequencing of human leukemia2010
- Author(s)
  Yamashita Y, Yuan J, Suetake I, Suzuki H, Ishikawa Y, Choi YL, Ueno T, Soda M, Hamada T, Haruta H, Takada S, Miyazaki Y, Kiyoi H, Ito E, Naoe T, Tomonaga M, Toyota M, Tajima S, Iwama A, Mano H.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 3723-3731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Selective KIT inhibitor KI-328 and HSP90 inhibitor show different potency against the type of KIT mutations recurrently identified in acute myeloid leukemia2010
- Author(s)
  Tsujimura A, Kiyoi H, Shiotsu Y, Ishikawa Y, Mori Y, Ishida H, Toki T, Ito E, Naoe T.
- Journal Title
  
  Int J Hematol
  
  Volume: 92 Pages: 624-633
- NAID
  10027673999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Irrespective of CD34 expression, lineage-committed cell fraction reconstitutes and re-establishes transformed Philadelphia chromosome-positive leukemia in NOD/SCID/IL-2Rgammac mice2010
- Author(s)
  Tanizaki R, Nomura Y, Miyata Y, Minami Y, Abe A, Hanamura A, Sawa M, Murata M, Kiyoi H, Matsushita T, Naoe T.
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 631-638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Down-regulation of CD20 expression in B-cell lymphoma cells after treatment with rituximab-containing combination chemotherapies : its prevalence and clinical significance.2009
- Author(s)
  Hiraga J, Tomita A, Sugimoto T, Shimada K, Ito M, Nakamura S, Kiyoi H, Kinoshita T, Naoe T
- Journal Title
  
  Blood (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591116
[Journal Article] Escape mechanisms from antibody therapy to lymphoma cells : Downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation.2009
- Author(s)
  Sugimoto T, Tomita A, Hiraga J, Shimada K, Kiyoi H, Kinoshita T, Naoe T
- Journal Title
  
  Biochem Biophys Res Commun. 390(1)
  
  Pages: 48-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591116
[Journal Article] Down-regulation of CD20 expression in B-cell lymphoma cells after treatment with rituximab-containing combination chemo the rapies : its prevalence and clinical significance2009
- Author(s)
  Hiraga J, Tomita A, Sugimoto T, Shimada K, Ito M, Nakamura S, Kiyoi H, Kinoshita T, Naoe T.
- Journal Title
  
  Blood
  
  Volume: 113 Pages: 4885-4893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Escape mechanisms from antibody therapy to lymphoma cells : down regulation of CD 20 mRNA by recruitment of the HDAC complex and not by DNA methylation2009
- Author(s)
  Sugimoto T, Tomita A, Hiraga J, Shimada K, Kiyoi H, Kinoshita T, Naoe T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 390 Pages: 48-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Escape mechanisms from antibody therapy to lymphoma cells : Downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation.2009
- Author(s)
  Sugimoto T, Tomita A, Hiraga J, Shimada K, Kiyoi H, Kinoshita T, Naoe T.
- Journal Title
  
  Biochem Biophys Res Commun. 390
  
  Pages: 48-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591116
[Journal Article] Down-regulation of CD20 expression in B-cell lymphoma cells after treatment with rituximab-containing combination chemotherapies: its prevalence and clinical significance.2009
- Author(s)
  Hiraga J, Tomita A, Sugimoto T, Shimada K, Ito M, Nakamura S, Kiyoi H, Kinoshita T, Naoe T
- Journal Title
  
  Blood 113(20)
  
  Pages: 4885-4893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591116
[Journal Article] KW-2449, a novel multi-kinase in hibit or, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutatedBCR/ABL translocation2009
- Author(s)
  Shiotsu Y, Kiyoi H, Ishikawa Y, Tanizaki R, Shimizu M, Umehara H, Ishii K, Mori Y, Ozeki K, Minami Y, Abe A, Maeda H, Akiyama T, Kanda Y, Sato Y, Akinaga S, Naoe T.
- Journal Title
  
  Blood
  
  Volume: 114 Pages: 1607-1617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Down-regulation of CD20 expression in B-cell lymphoma cells after treatment with rituximab-containing combination chemotherapies : its prevalence and clinical significance.2009
- Author(s)
  Hiraga J, Tomita A, Sugimoto T, Shimada K, Ito M, Nakamura S, Kiyoi H, Kinoshita T, Naoe T.
- Journal Title
  
  Blood 113
  
  Pages: 4885-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591116
[Journal Article] Comprehensive analysis of cooperative gene mutations between class I and class II in de novo acute myeloid leukemia2009
- Author(s)
  Ishikawa Y, Kiyoi H, Tsujimura A, Miyawaki S, Miyazaki Y, Kuriyama K, Tomonaga M, Naoe T.
- Journal Title
  
  Eur J Haematol
  
  Volume: 83 Pages: 90-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198
[Journal Article] Abnormal cytoplasmic dyslocalisation and/or reduction of nucleophosm in protein level rarely occurs in myelodysplastic syndromes.2008
- Author(s)
  Ishikawa Y, Xu J, Sakashita G, Urano T, Suzuki T, Tomita A, Kiyoi H, Nakamura S, Naoe T
- Journal Title
  
  Leuk Lymphoma. 49
  
  Pages: 2359-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591116
[Journal Article] Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome.2008
- Author(s)
  Xu J, Suzuki M, Niwa Y, Hiraga J, Nagasaka T, Ito M, Nakamura S, Tomita A, Abe A, Kiyoi H, Kinoshita T, Naoe T
- Journal Title
  
  Br J Haematol. 140(4)
  
  Pages: 394-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591116
[Journal Article] Abnormal cytoplasmic dyslocalisation and/or reduction of nucleophosmin protein level rarely occurs in myelodysplastic syndromes2008
- Author(s)
  Ishikawa Y, Xu J, Sakashita G, Urano T, Suzuki T, Tomita A, Kiyoi H, Nakamura S, Naoe T
- Journal Title
  
  Leuk Lymphoma. 49(12)
  
  Pages: 2359-2364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591116
[Journal Article] JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adults2007
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Leukemia 21
  
  Pages: 574-576
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591054
[Journal Article] JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adults.2007
- Author(s)
  Kiyoi H
- Journal Title
  
  Leukemia (in Press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390276
[Journal Article] JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adults.2007
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Leukemia in press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390276
[Journal Article] A novel FLT3 inhibitor FI-700 selectively suppress the growth of leukemia cells with FLT3 mutations2007
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 4575-4582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18014010
[Journal Article] JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adults.2007
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Leukemia 21
  
  Pages: 574-576
- Data Source
  KAKENHI-PROJECT-18591054
[Journal Article] JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adults.2007
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Leukemia 21
  
  Pages: 574-576
- Data Source
  KAKENHI-PROJECT-18014010
[Journal Article] A novel FLT3 inhibitor FI-700 selectively suppress the growth of leukemia cells with FLT3 mutations2007
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 4575-4582
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591054
[Journal Article] FLT3 mutations in acute myeloid leukemia.2006
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Methods Mol Med 125
  
  Pages: 189-197
- Data Source
  KAKENHI-PROJECT-18591054
[Journal Article] FLT3 mutations in acute myeloid leukemia.2006
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Methods Mol Med 125
  
  Pages: 189-197
- Data Source
  KAKENHI-PROJECT-18014010
[Journal Article] FLT3 mutations in acute myeloid leukemia.2006
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Methods Mol Med 125
  
  Pages: 189-197
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390276
[Journal Article] Biology, clinical relevance, and moleculary targeted therapy in acute leukemia with FLT3 mutations.2006
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Int J Hematol 83
  
  Pages: 301-308
- Data Source
  KAKENHI-PROJECT-18591054
[Journal Article] FLT3 mutations in acute myeloid leukemia.2006
- Author(s)
  Kiyoi H
- Journal Title
  
  Methods Mol Med 125
  
  Pages: 189-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390276
[Journal Article] Biology, clinical relevance, and moleculary targeted therapy in acute leukemia with FLT3 mutations2006
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Int J Hematol 83
  
  Pages: 301-308
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591054
[Journal Article] Biology, clinical relevance, and moleculary targeted therapy in acute leukemia with FLT3 mutations.2006
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Int J Hematol 83
  
  Pages: 301-308
- Data Source
  KAKENHI-PROJECT-18014010
[Journal Article] FLT3 mutations in acute myeloid leukemia2006
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Methods Mol Med 125
  
  Pages: 189-197
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591054
[Journal Article] FLT3 mutations in ante myeloid leukemia2006
- Author(s)
  Kiyoi, H
- Journal Title
  
  Methods Mol Med 125
  
  Pages: 189-197
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591054
[Journal Article] Clinical significance of FLT3 in leukemia.2005
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Int J Hematol 82
  
  Pages: 85-92
- Data Source
  KAKENHI-PROJECT-17015021
[Journal Article] Clinical significance of FLT3 in leukemia.2005
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Int J Hematol 82
  
  Pages: 85-92
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590932
[Journal Article] Clinical significance of FLT3 in leukemia.2005
- Author(s)
  Hitoshi Kiyoi
- Journal Title
  
  Int J Hematol 82
  
  Pages: 85-92
- Data Source
  KAKENHI-PROJECT-17590991
[Presentation] Refractory acute promyelocytic leukemia clones’ biological significance by patient-derived xenograft2023
- Author(s)
  Takashi Kurokawa, Yuichi Ishikawa, Yoko Ushijima, Naomi Kawashima,　Satoshi Iwata, Seara Naruse, Jeong-Hui Kim, Marie Nakashima, Takahiro Nishiyama, Takanobu Morishita, Norihiro Ueda, Koichi Watamoto, Tetsuya Nishida, Kunio Kitamura, Hitoshi Kiyoi
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27624
[Presentation] Analysis of Metabolic Mechanism of CD19CAR-T with CD79A/CD40 Co-Stimulatory Domain Based on Comparison with Established CAR-Ts2023
- Author(s)
  Takeuchi, Yuki; Terakura, Seitaro; Hirano, Shiho; Yokota, Hirofumi; Kuwano, Shihomi; Osaki, Masahide; Adachi, Yoshitaka; Imai, Kanae; Julamanee, Jakrawadee; Hanajiri, Ryo; Murata, Makoto; Kiyoi, Hitoshi
- Organizer
  65th Annual Meeting of the American-Society-of-Hematology (ASH)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27624
[Presentation] Development and Efficacy of a Novel Bromodomain and Extraterminal Domain Degrader K-256 in MYC/BCL2-Related Lymphoma2023
- Author(s)
  Furukawa, Kastuya; Shimada, Kazuyuki; Esaki, Masahiro; Tanaka, Kentaro; Yamamoto, Keisuke; Mori, Kiyotoshi; Kiyoi, Hitoshi
- Organizer
  65th Annual Meeting of the American-Society-of-Hematology (ASH)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27624
[Presentation] Suppression of Super-Enhancer-Driven TAL1 Expression By KLF4 in T-Cell Acute Lymphoblastic Leukemia2023
- Author(s)
  Noura, Mina; Yasuda, Takahiko; Tsuzuki, Shinobu; Matsuo, Hidemasa; Kiyoi, Hitoshi; Hayakawa, Fumihiko
- Organizer
  65th Annual Meeting of the American-Society-of-Hematology (ASH)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27624
[Presentation] The efficacy of BTK inhibitor in IVLBCL preclinical mouse models.2023
- Author(s)
  Takai, Mika; Shimada, Kazuyuki; Kiyoi, Hitoshi
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27624
[Presentation] Phase I Study of Cord Blood Transplantation with Intra-Bone Marrow Injection of Mesenchymal Stem Cells2019
- Author(s)
  Tatsunori Goto, Makoto Murata, Tetsuya Nishida, Seitaro Terakura, Sonoko Kamoshita, Yuichi Ishikawa, Yoko Ushijima, Yoshiya Adachi, Katsuyoshi Kato, Akihiro Hirakawa, Satoshi Nishiwaki, Nobuhiro Nishio, Yoshiyuki Takahashi, Yoshihisa Kodera, Tadashi Matsushita, Hitoshi Kiyoi
- Organizer
  米国血液学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] 急性骨髄性白血病白血病に対するクリニカルシークエンス実行可能性を検証する多施設共同研究2019
- Author(s)
  横山寿行, 安田貴彦, 石川裕一, 臼杵憲祐,　矢野真吾,　伊藤良和,　康史朗,　木口亨,　宮田泰彦, 清井仁, 松村到, 宮﨑泰司, 服部浩佳, 西島大, 山本松雄, 齋藤明子, 倉橋浩樹, 白石友一, 宮野悟, 真田昌, 小川誠司, 堀部敬三
- Organizer
  日本血液学会年次総会
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Development of Predictive Biomarker and Optimal Treatment Strategy with FLT3 Inhibitors in Acute Myeloid Leukemia2019
- Author(s)
  Jeong Hui Kim, Yasuhiko Harada, Yuichi Ishikawa, Naomi Kawashima, Marie Nakashima, Yoko Ushijima, Takahiro Nishiyama, Tatsunori Goto, Nobuaki Fukushima, Rika Kihara, Tomohiro Kajiguchi, Koichi Watamoto, Akio Kohno, Kunio Kitamura, Yukiyasu Ozawa, Hitoshi Kiyoi
- Organizer
  米国血液学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] FLT3-ITD 変異陽性AML に対する第一寛解期での同種造血幹細胞移植； JALSG AML209-FLT3-SCT Study 結果2019
- Author(s)
  川島直実, 石川裕一, 熱田由子, 澤正史, 小澤幸泰, 林正樹, 河野彰夫, 冨田章裕,前田智也, 堺田惠美子, 臼杵憲祐, 萩原真紀, 金森平和, 松岡広, 小林美希,麻生範雄, 大竹茂樹, 松村到, 宮﨑泰司, 直江知樹, 清井仁
- Organizer
  日本血液学会年次総会
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Guided Polarization of iPSC-Derived CD4SP Helper T Cells By CRISPR/Cas9-Based Genome-Editing2019
- Author(s)
  Hisashi Yano, Tokuyuki Shinohara, Keiko Koga, Shoichi Iriguchi, Yasuyuki Miyake, Xuewei Song, Megumi Tada, Yoshiaki Kassai, Hitoshi Kiyoi, Shin Kaneko
- Organizer
  米国血液学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] 急性骨髄性白血病に対するレセプター型チロシンキナーゼの細胞膜発現阻害薬の開発とその有効性2019
- Author(s)
  中島麻梨絵, 江嵜正浩, 石川裕一, 川島直実, 金貞姫, 原田靖彦, 牛島洋子, 石井俊彦, 森聖寿, 清井仁
- Organizer
  日本血液学会年次総会
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] FLT3変異陽性AML細胞における野生型FLT3の発現とFLT3阻害剤の阻害活性2019
- Author(s)
  金貞姫, 石川裕一, 川島直実, 中島麻梨絵, 原田靖彦, 牛島洋子, 清井仁
- Organizer
  日本血液学会年次総会
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Prospective Comparison of Azacitidine Treatment between 7-Days and 5-Days Schedules for Patients with Higher-Risk Myelodysplastic Syndromes; Results of Japan Adult Leukemia Study Group MDS212 Trial2019
- Author(s)
  Toru Kiguchi, Hitoshi Kiyoi, Tomoki Naoe, Yasushi Miyazaki
- Organizer
  米国血液学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] AMLにおけるFLT3阻害剤の効果予測バイオマーカーと至適治療法の開発2019
- Author(s)
  原田靖彦, 石川裕一, 川島直実, 金貞姫, 中島麻梨絵, 足立佳也, 牛島洋子, 清井仁
- Organizer
  日本血液学会年次総会
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Discovery of a Novel Dihydroorotate Dehydrogenase Inhibitor That Induces Differentiation and Overcomes Ara-C Resistance of Acute Myeloid Leukemia Cells2019
- Author(s)
  Satoshi Kitazawa, Yukiko Ishii, Keiko Makita-Suzuki, Koichi Saito, Kensuke Takayanagi, Hiromi Sugihara, Shun Matsuda, Takayuki Yamakawa, Yasuhiro Tsutsui, Tadashi Tanaka, Tomohisa Hatta, Tohru Natsume, Toru Kondo, Yuichi Ishikawa, Shinji Hagiwara, Hitoshi Kiyoi
- Organizer
  米国血液学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Prospective Evaluation of Allogeneic HSCT at the First Remission for Younger Adults with FLT3 -ITD Positive Acute Myeloid Leukemia: The JALSG AML209-FLT3-SCT Study2019
- Author(s)
  Naomi Kawashima, Yuichi Ishikawa, Yoshiko Atsuta, Hitoshi Kiyoi
- Organizer
  米国血液学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Staurosporine Induces Caspase-Dependent Proteolysis of MEF2D-Fusion Protein and Cell Death Selective to MEF2D-Fusion-Positive ALL Cells2019
- Author(s)
  Naoyuki Tange, Fumihiko Hayakawa, Takahiko Yasuda, Hideyuki Yamamoto, Daiki Hirano, Shinobu Tsuzuki, Hitoshi Kiyoi
- Organizer
  米国血液学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] FF-10101 Retains Potent Inhibitory Activities Against Resistant Mutations to FLT3 Inhibitors, Newly Identified in Random Mutagenesis Screens2019
- Author(s)
  Yuichi Ishikawa, Koichi Saito, Naomi Kawashima, Michie Morimoto, Hidetoshi Murao, Daisuke Terada, Takeshi Yamaura, Shinji Hagiwara, Hitoshi Kiyoi
- Organizer
  米国血液学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] The Optimal Treatment Strategy for Adult Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia in First Complete Remission in the Era of High-Intensity Chemotherapy2019
- Author(s)
  Shinichi Kako,Hitoshi Kiyoi, Itaru Matsumura, Yasushi Miyazaki, Yoshiko Atsuta
- Organizer
  米国血液学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Favorable Outcomes of Newly Diagnosed Intravascular Large B-Cell Lymphoma Patients Treated with R-CHOP Combined with High-Dose Methotrexate Plus Intrathecal Chemotherapy: Results from a Multicenter Phase 2 Trial (PRIMEUR-IVL)2019
- Author(s)
  Kazuyuki Shimada, Hitoshi Kiyoi, Ritsuro Suzuki, Takashi Tokunaga, Shigeo Nakamura, Tomohiro Kinoshita
- Organizer
  米国血液学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Prospective Evaluation of Prognostic Relevance of KIT Mutations in Core-Binding Factor Acute Myeloid Leukemia: Results from the JALSG CBF-AML209-KIT Study2018
- Author(s)
  Kawashima N, Ishikawa Y, Kiyoi H, Atsuta Y, Ohtake S, Asou N, Miyazaki Y
- Organizer
  第60回　American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Clinical significance of ASXL2 and ZBTB7A mutations and AML1-ETO9a expression in AML with t(8;21): the JALSG AML201 study.2018
- Author(s)
  Kawashima N, Ishikawa Y, Kiyoi H, Atsuta Y, Ohtake S, Asou N, Miyazaki Y
- Organizer
  第37回　International Society of Hematology. Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Dynamics of Genetic Landscapes and Clonal Evolution between Patients and PDX Models in Acute Myeloid Leukemia.2018
- Author(s)
  Kawashima N, Ishikawa Y, Kiyoi H
- Organizer
  第60回　American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Clonal Analysis of Acute Myeloid Leukemia secondary to Myeloproliferative Neoplasms2017
- Author(s)
  Yoko Ushijima, Yuichi Ishikawa, Hikaru Hattori, Naomi Kawashima, Shun Fujiwara, Seitaro Terakura, Masashi Sanada, Hitoshi Kiyoi
- Organizer
  59th annual meeting of american society of hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] High expression of MEF2D-fusion protein by escaping from the regulation by microRNA2017
- Author(s)
  Daiki Hirano, Fumihiko Hayakawa, Takahiko Yasuda, naoyuki Tange, Hideyuki Yamamoto, Yuki Kojima, Takanobu Morishita, Naoto Imoto, Shinobu Tsuzuki, Hiroyuki Mano, Tomoki Naoe, Hitoshi Kiyoi
- Organizer
  59th annual meeting of american society of hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09921
[Presentation] Lymph node-associated stromal fibroblasts support B-cell lymphoma cells via the PI3K pathway.2015
- Author(s)
  坂本明彦、島田和之、片山幸、早川文彦、冨田章裕、清井仁.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] リンパ節関連の間質性線維芽細胞は液性因子を分泌することでB細胞リンパ腫細胞を支持する.2015
- Author(s)
  坂本明彦、島田和之、片山幸、早川文彦、冨田章裕、清井仁.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] 1353 Development of FF-10101, a Novel Irreversible FLT3 Inhibitor, Which Overcomes Drug Resistance Mutations.2015
- Author(s)
  Toshiyuki Nakatani,Ken Uda, Takeshi Yamaura, Masaru Takasaki, Akimi Akashi, Fangli Chen, , Yuichi Ishikawa, Fumihiko Hayakawa, Shinji Hagiwara, Hitoshi Kiyoi, and Tomoki Naoe
- Organizer
  57th ASH Annual Meeting and Exposition
- Place of Presentation
  Orange County Convention Center(米国)
- Year and Date
  2015-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] A Photosensitizer Verteporfin Has Light-Independent Anti-Leukemic Activity for Ph-Positive Acute Lymphoblastic Leukemia and Synergistically Works with Dasatinib in Vivo.2015
- Author(s)
  Takanobu Morishita, Fumihiko Hayakawa, Keiki Sugimoto, Daiki Hirano, Yuki Kojima, Naoto Imoto, Yuichiro Inagaki, Tomoki Naoe and Hitoshi Kiyoi.
- Organizer
  57th ASH Annual Meeting and Exposition
- Place of Presentation
  Orange County Convention Center(米国)
- Year and Date
  2015-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Lymph node-associated stromal fibroblasts as a potential source of humoral factors to support B-cell lymphoma cells via the phosphatidylinositol 3-kinase pathway2015
- Author(s)
  坂本明彦、島田和之、片山幸、早川文彦、冨田章裕、清井仁
- Organizer
  第44回国際実験血液学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Drug repositioning by patient-derived-xenograft screening for the discovery of new cure for PhALL.2015
- Author(s)
  森下喬允、早川文彦、小島勇貴、井本直人、稲垣裕一郎、杉本慶樹、直江知樹、清井仁
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] SPIB expression is a novel poor prognostic factor in DLBCL.2015
- Author(s)
  髙木雄介、島田和之、島田聡子、早川文彦、坂本明彦、中村栄男、冨田章裕、清井仁.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Ph陽性ALL新規治療薬発見のためのPDXスクリーニングによるドラッグリポジショニング.2015
- Author(s)
  森下喬允、早川文彦、杉本慶樹、直江知樹、清井仁.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] 末梢血 cell-free DNA を用いた B 細胞リンパ腫における遺伝子変異解析2014
- Author(s)
  鈴木康裕、冨田章裕、吉田健一、島田和之、入山智沙子、真田昌、白石友一、千葉健一、田中洋子、宮野悟、小川誠司、清井仁.
- Organizer
  第73回　日本癌学会学術集会
- Place of Presentation
  神奈川県、横浜市、パシフィコ横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] 末梢血遊離DNAを用いたB細胞リンパ腫における遺伝子変異解析2014
- Author(s)
  鈴木康裕、冨田章裕、入山智沙子、島田和之、吉田健一、小川誠司、清井仁
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪府、大阪市、大阪国際会議場
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] Utilization of Peripheral Blood Cell-free DNA for Genetic Analyses in MDS.2014
- Author(s)
  Yasuhiro Suzuki, Akihiro Tomita, Chisako Iriyama, Kazuyuki Shimada, Hitoshi Kiyoi.
- Organizer
  The XXXVth World Congress of the International Society of hematology. (oral presentation)
- Place of Presentation
  Beijing, China
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] 抗CD20抗体薬治療効果に対して重要なFcγレセプターのSNPの検出2014
- Author(s)
  入山智沙子、Chantal Hargreaves, Matthew Rose-Zerilli, Jonathan Strefford, Mark Cragg, 島田和之、直江知樹、冨田章裕、清井仁
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪府、大阪市、大阪国際会議場
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] Clinical and Molecular Significance of Peripheral Blood Cell-Free DNA in B-Cell Lymphomas for Detection of Genetic Mutations and Correlation with Disease Status.2014
- Author(s)
  Yasuhiro Suzuki, Akihiro Tomita, Kenichi Yoshida, Kazuyuki Shimada, Chisako Iriyama, Masashi Sanada, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Seishi Ogawa, and Hitoshi Kiyoi.
- Organizer
  The American Society of Hematology, 56th Annual Meeting.
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] 骨髄スメア標本とパイロシークエンス法を用いたB細胞性腫瘍におけるMYD88 L265P変異解析2014
- Author(s)
  鈴木康裕、冨田章裕、入山智沙子、島田和之、山本絵里奈、金田典雄、清井仁
- Organizer
  第12回　日本臨床腫瘍学会総会（口演）
- Place of Presentation
  福岡県、福岡市、福岡国際会議場
- Year and Date
  2014-07-18
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] Biological and genetic analyses of intravascular large B-cell lymphoma using xenograft mouse model.2014
- Author(s)
  島田和之、島田聡子、杉本慶樹、早川文彦、片山幸、平川晃弘、中村栄男、瀬戸加大、直江知樹、冨田章裕、清井仁
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪府、大阪市、大阪国際会議場
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] Development and Analysis of Novel Intravascular Large B-Cell Lymphoma NOD/Shi-Scid IL2Rγnull Mouse Xenograft Model.2014
- Author(s)
  Kazuyuki Shimada, Satoko Shimada, Keiki Sugimoto, Fumihiko Hayakawa, Miyuki Katayama, Akihiro Hirakawa, Yusuke Takagi, Shigeo Nakamura, Masao Seto, Tomoki Naoe, Akihiro Tomita and Hitoshi Kiyoi.
- Organizer
  The American Society of Hematology, 56th Annual Meeting. (oral presentation)
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2014-12-08
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] 骨髄スメア標本とパイロシークエンス法を用いたWM/LPLにおけるMYD88 L265P変異解析2014
- Author(s)
  鈴木康裕、冨田章裕、入山智沙子、島田和之、日比陽子、中村文香、山本絵里菜、金田典雄、清井仁
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪府、大阪市、大阪国際会議場
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] Prognostic impacts and clonal heterogeneity　of recurrently identified mutations in AML2013
- Author(s)
  清井仁
- Organizer
  XXVI Symposium IACRLRD
- Place of Presentation
  トリノ（イタリア）
- Invited
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] Prognostic Re-Classification of Adult Acute Myeloid Leukemia Based on the Comprehensive Genetic Analysis2013
- Author(s)
  1) 清井仁、木原里香、鈴木弘太郎、陳昉里、加藤貴大、山本絵里奈、直江知樹、小川誠司、永田安伸、麻生範雄、大竹茂樹、宮脇修一、宮崎泰司、佐倉徹、小澤幸泰、薄井紀子、金森平和、木口亨、今井陽俊、鵜池直邦、木村文彦、北村邦朗、中世古千昭、坪井康介、竹下明裕、石田文宏、鈴島仁、加藤裕一、三輪啓志
- Organizer
  The 18th Congress of EHA
- Place of Presentation
  ストックホルム（スウェーデン）
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] Tratment with Hedgehog inhibitor,PF-04449913, atteuates leukemia-initiation potential in acute mveloid leukemia cells2013
- Author(s)
  Nobuaki Fukushima,Yosuke Minami,Fumihiko Hayakawa,Hitoshi Kiyoi, Anil Sadarangani, PhD3*, Catriona HM Jamieson,Tomoki Naoe
- Organizer
  米国血液学会
- Place of Presentation
  ニューオリンズ
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] 正常及び変異FLT3共発現細胞の細胞増殖及びFLT3阻害剤効果に対するFLの抑制効果2013
- Author(s)
  陳昉里、清井仁、直江知樹、木原里香、直江知樹
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] 正常及び変異FLT３共発現細胞の細胞増殖及びFLT3阻害剤効果に対するFLの抑制効果2013
- Author(s)
  陳昉里、中谷俊幸、木原里香、清井仁、直江知樹
- Organizer
  日本血液学会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Analysis of rituximab resistance mechanism in CD20 positive B-cell lymphoma cells.2013
- Author(s)
  Kazuyuki Shimada, Akihiro Tomita, Takashi Tokunaga, Chisako Iriyama, Tomohiro Kinoshita, Hitoshi kiyoi, Cragg Mark, Tomoki Naoe.
- Organizer
  日本血液学会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] 急性骨髄性白血病における分子標的治療薬の開発2012
- Author(s)
  清井　仁
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] CD20 IHC+/FCM- DLBCL - the molecular mechanisms and the clinical significances.2012
- Author(s)
  Takashi Tokunaga,　Akihiro Tomita, Tatsuya Hirose,　Keiki Sugimoto,　Kazuyuki Shimada,　Hitoshi Kiyoi,　Tomohiro Kinoshita,　Tomoki Naoe.
- Organizer
  第74回　日本血液学会総会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] Usefulness of Peripheral Blood Circulating DNAs As an Alternative to DNA From Bone Marrow Cells to Detect CpG Global Methylation Status and Genetic Mutations in Patients with Myelodysplastic Syndromes.2012
- Author(s)
  Chisako Iriyama, Akihiro Tomita, Hideaki Hoshino, Mizuho Shirahata, Yoko Hibi, Kiyofumi Yamada, Hitoshi Kiyoi, and Tomoki Naoe.
- Organizer
  The American Society of Hematology, 54th Annual Meeting
- Place of Presentation
  Georgia World Congress Center Atlanta, Atlanta, GA, USA
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] Peripheral blood circulating DNAs to detect CpG global methylation and genetic mutations in MDS.2012
- Author(s)
  Chisako Iriyama,　Akihiro Tomita,　Yasuhiro Suzuki,　Mizuho Shirahata,　Yoko Hibi,　Kiyofumi Yamada,　Hitoshi Kiyoi,　Tomoki Naoe.
- Organizer
  第74回　日本血液学会総会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] 白血病治療の現状と将来2012
- Author(s)
  清井　仁
- Organizer
  第50回日本癌治療学会総会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] EVI1 elicits resistance to apoptosis which can be overcome through application of AKTi or ABT-737.2012
- Author(s)
  Kazuyuki Shimada,　Akihiro Tomita,　Yosuke Minami,　Akihiro Abe,　Charlotte Hind,　Hitoshi Kiyoi,　Mark Cragg,　Tomoki Naoe.
- Organizer
  第74回　日本血液学会総会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] Rituximab Sensitivity to De Novo DLBCL Cells Showing the Specific Phenotype of CD20 Protein Immunohistochemistry-Positive / Flow Cytometory-Negative: Analyses of Its Clinical Significances and the Molecular Mechanisms.2012
- Author(s)
  Akihiro Tomita, Takashi Tokunaga, Tatsuya Hirose, Keiki Sugimoto, Kazuyuki Shimada, Norio Kaneda, Hitoshi Kiyoi, Naoko Asano, Shigeo Nakamura, Tomohiro Kinoshita, and Tomoki Naoe.
- Organizer
  The American Society of Hematology, 54th Annual Meeting
- Place of Presentation
  Georgia World Congress Center Atlanta, GA, USA
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] AML study in JALSG2011
- Author(s)
  Hitoshi Kiyoi
- Organizer
  The Korean Society of Hematology KSH and JALSG joint symposium
- Place of Presentation
  Asan Medical Center (Seoul, Korea)(招待講演)
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-21591198
[Presentation] AML病態研究の進展と最近の治療エビデンス2011
- Author(s)
  清井仁
- Organizer
  第73回日本血液学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)(招待講演)
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-21591198
[Presentation] 急性骨髄性白血病における分子病態に基づく予後層別化と個別化治療2011
- Author(s)
  清井仁
- Organizer
  第49回日本癌治療学会総会(招待講演)
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-21591198
[Presentation] 急性骨髄性白血病における分子病態に基づく予後層別化と個別化治療2011
- Author(s)
  清井仁
- Organizer
  第49回日本癌治療学会総会
- Place of Presentation
  名古屋国際会議場(愛知県)(招待講演)
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-21591198
[Presentation] AML病態研究の進展と最近の治療エビデンス2011
- Author(s)
  清井仁
- Organizer
  第73回日本血液学会学術総会(招待講演)
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-21591198
[Presentation] CD20-Negative Phenotypic Change In B-Cell Lymphoma Cells After Using Rituximab : Possibility of a Particular Clinicopathologic Phenomenon Post- Rituximab Extranodal CD20-Negative Lymphoma. (Poster)2010
- Author(s)
  Akihiro Tomita, Takashi Tokunaga, Chisako Iriyama Kazuyuki Shimada, Junji Hiraga, Takumi Sugimoto, Hitoshi Kiyoi, Shigeo Nakamura, Tomohiro Kinoshita, Tomoki Naoe.
- Organizer
  The American Society of Hematology, 52th Annual Meeting
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] CD20-Negative Phenotypic Change In B-Cell Lymphoma Cells After Using Rituximab: Possibility of a Particular Clinicopathologic Phenomenon Post- Rituximab Extranodal CD20-Negative Lymphoma2010
- Author(s)
  冨田章裕, 徳永隆之, 入山智沙子, 島田和之, 平賀潤二, 杉本匠, 清井仁, 中村栄男, 木下朝博士, 直江知樹
- Organizer
  The American Society of Hematology, 52th Annual Meeting
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] 亜ヒ酸耐性耐性に重要なPML-RARAのミスセンス変異(口演)2010
- Author(s)
  後藤絵美、冨田章裕、早川文彦、渥美晃秀、清井仁、直江知樹
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Prognostic classification and the development of individual therapy based on the genetic alterations in AML2010
- Author(s)
  Hitoshi Kiyoi
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21591198
[Presentation] パイロシークエンス法を用いた骨髄、末梢血、血清血漿遊離DNAにおけるTET2遺伝子変異の解析2010
- Author(s)
  入山智沙子、冨田章裕、星野秀明、清井仁、日比陽子、千崎康司、山田清文、真田昌、小川誠司、直江知樹
- Organizer
  第70回日本血液学会総会、(口演)
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] 悪性腫瘍細胞に発現する異常アンチセンスキメラRNAによる特定遺伝子発現のノックダウン.2010
- Author(s)
  冨田章裕、杉本匠、安部明弘、清井仁、直江知樹
- Organizer
  第4回日本エピジェネティクス研究会
- Place of Presentation
  米子
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] 亜ヒ酸耐性耐性に重要なPML-RARAのミスセンス変異2010
- Author(s)
  後藤絵美、冨田章裕、早川文彦、渥美晃秀、清井仁、直江知樹
- Organizer
  第70回日本血液学会総会、(口演)
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Prognostic classification and the development of individual therapy based on the genetic alterations in AML.2010
- Author(s)
  Hitoshi Kiyoi
- Organizer
  第69回日本癌学会総会(シンポジウム)
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21591198
[Presentation] パイロシークエンス法を用いた骨髄、末梢血、血清血漿遊離DNAにおけるTET2遺伝子変異の解析(口演)2010
- Author(s)
  入山智沙子、冨田章裕、星野秀明、清井仁、日比陽子、千崎康司、山田清文、真田昌、小川誠司、直江知樹
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] 急性白血病の分子標的治療2010
- Author(s)
  清井仁
- Organizer
  第48回日本癌治療学会(招待講演)
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21591198
[Presentation] 急性白血病の分子標的治療2010
- Author(s)
  清井仁
- Organizer
  第48回日本癌治療学会(シンポジウム)
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21591198
[Presentation] 悪性腫瘍細胞に発現する異常アンチセンスキメラRNAによる特定遺伝子発現のノックダウン2010
- Author(s)
  富田章裕、杉本匠、安部明弘、清井仁、直江知樹
- Organizer
  第4回日本エピジェネティクス研究会、(ポスター)
- Place of Presentation
  米子
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Double Genetic Mutations in PML-Rara Fusion Gene Confirmed in a Patient Showing Resistance to All-Trans Retinoic Acid and Arsenic-Trioxide Therapy.2009
- Author(s)
  Emi Goto, Akihiro Tomita, Akihide Atsumi, Hitoshi Kiyoi, Tomoki Naoe.
- Organizer
  The American Society of Hematology, 51th Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] 染色体相互転座から転写されるアンチセンスキメラRNAによる特定遺伝子発現のノックダウン.2009
- Author(s)
  富田章裕、杉本匠、安部明弘、清井仁、直江知樹.
- Organizer
  第6回日本癌学会学術総会
- Place of Presentation
  神奈川
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] ATRAおよびATO治療に抵抗性を示したAPL患者に確認されたPML-RARα付加的遺伝子変異の解析.2009
- Author(s)
  後藤絵美、富田章裕、渥美晃秀、清井仁、直江知樹
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Epigenetic mechanisms of MS4Al(CD20)gene down-regulation in the CD20-negative B-lymphoma cells after treatment with rituximab.2009
- Author(s)
  Akihiro Tomita, Takumi Sugimoto, Junji Hiraga, Kazuyuki Shimada, Hitoshi Kiyoi, Tomohiro Kinoshita, Tomoki Naoe.
- Organizer
  International Conference on Differentiation Therapy.
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] 慢性骨髄性白血病由来樹立細胞株におけるTEL/EVI1融合遺伝子の機能解析.2009
- Author(s)
  島田和之、冨田章裕、南陽介、谷崎亮平、安部明弘、清井仁、木下朝博、直江知樹
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Double Genetic Mutations in PML-Rara Fusion Gene Confirmed in a Patient Showing Resistance to All-Trans Retinoic Acid and Arsenic-Trioxide Therapy.2009
- Author(s)
  高橋恵美子, 冨田章裕, 渥美晃秀, 清井仁, 直江知樹
- Organizer
  The American Society of Hematology, 51th Annual Meeting
- Place of Presentation
  New Orleans, LA, USA.
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Epigenetic mechanisms of MS4A1 (CD20) gene down-regulation in the CD20-negative B-lymphoma cells after treatment with rituximab.2009
- Author(s)
  Akihiro Tomita, Takumi Sugimoto, Junji Hiraga, Kazuyuki Shimada, Hitoshi Kiyoi, Tomohiro Kinoshita, Tomoki Naoe
- Organizer
  International Conference on Differentiation Therapy
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] MS4A1 (CD20) Gene Expression Is Down-Regulated by Recruiting the Histone Deacetylase Protein Complex to the Promoter in the CD20-Negative B-Lymphoma Cells After Treatment with Rituximab.2009
- Author(s)
  杉本匠, 冨田章裕, 平賀潤二, 島田和之, 清井仁, 木下朝博, 直江知樹
- Organizer
  The American Society of Hematology, 51th Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] ATRAおよびATO治療に抵抗性を示したAPL患者に確認されたPML-RARα付加的遺伝子変異の解析2009
- Author(s)
  後藤絵美、富田章裕、渥美晃秀、清井仁、直江知樹
- Organizer
  第71回日本血液学会総会、(ポスター)
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] 染色体相互転座から転写されるアンチセンスキメラRNAによる特定遺伝子発現のノックダウン2009
- Author(s)
  杉本匠、富田章裕、安部明弘、清井仁、直江知樹.
- Organizer
  第71回日本血液学会総会、(口演)
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] 慢性骨髄性白血病由来樹立細胞株におけるTEL/EVI1融合遺伝子の機能解析.2009
- Author(s)
  島田和之、冨田章裕、南陽介、谷崎亮平、安部明弘、清井仁、木下朝博1直江知樹.
- Organizer
  第71回日本血液学会総会、(ポスター)
- Place of Presentation
  京都
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] MS4Al(CD20)Gene Expression Is Down-Regulated by Recruiting the Histone Deacetylase Protein Complex to the Promoter in the CD20-Negative B-Lymphoma Cells After Treatment with Rituximab.2009
- Author(s)
  Takumi Sugimoto, Akihiro Tomita, Junji Hiraga, Kazuyuki Shimada, Hitoshi Kiyoi, Tomohiro Kinoshita, Tomoki Naoe,
- Organizer
  The American Society of Hematology, 51th Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] 染色体相互転座から転写されるアンチセンスキメラRNAによる特定遺伝子発現のノックダウン.2009
- Author(s)
  杉本匠、富田章裕、安部明弘、清井仁、直江知樹.
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] MDS患者に認められたt(12;17)により生じる新規TEL/ETV6融合遺伝子の解析2008
- Author(s)
  杉本匠、冨田章裕、安部明弘、清井仁、直江知樹
- Organizer
  第70回日本血液学会総会、(ポスター)
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Relationship between post-translational modification of CD20 protein and the responsiveness to rituximab treatment.2008
- Author(s)
  杉本匠, 富田章裕, 島田和之, 平賀潤二, 清井仁, 木下朝博, 直江知樹
- Organizer
  The American Society of Hematology, 50th Annual Meeting
- Place of Presentation
  San Francisco, CA, USA.
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] MDS患者に認められたt(12 ; 17)により生じる新規TEL/ETV6融合遺伝子の解析2008
- Author(s)
  杉本匠, 冨田章裕, 安部明弘, 清井仁, 直江知樹
- Organizer
  第70回曰本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Significance of CD20 protein expression pattern in rituximab-resistant B-cell lymphoma cells.2008
- Author(s)
  Akihiro Tomita, Junji Hiraga, Hitoshi Kiyoi, Masafumi Ito, Tomohiro Kinoshita, Tomoki Naoe
- Organizer
  第67回日本癌学会学術総会、(English Workshop ; 英語口演)
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Significance of CD20 protein expression pattern in rituximab-resistant B-cell lymphoma cells. (English Workshop ; 口演)2008
- Author(s)
  Akihiro Tomita, Junji Hiraga, Hioshi Kiyoi, Masafumi Ito, Tomohiro Kinoshita, Tomoki Naoe.
- Organizer
  第67回曰本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Relationship between post-translational modification of CD20 protein and the responsiveness to rituximab treatment.2008
- Author(s)
  Takumi Sugimoto, Akihiro Tomita, Kazuyuki Shimada, Junji Hiraga, Hitoshi Kiyoi, Tomohiro Kinoshita, Tomoki Naoe.
- Organizer
  The American Society of Hematology 50th Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-20591116
[Presentation] Implication of the Ets family transcription factor, SPIB, as the novel prognostic factor in DLBCL.
- Author(s)
  高木雄介、島田和之、冨田章裕、島田聡子、白幡瑞穂、鈴木康裕、山本絵里奈、野口俊助、中村栄男、清井仁、直江知樹.
- Organizer
  際75回　日本血液学会学術集会（口演）
- Place of Presentation
  ロイトン札幌（札幌市）
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] B細胞受容体シグナル経路によるリン酸化を介したPAX5の機能調節
- Author(s)
  稲垣裕一郎、早川文彦、清井仁
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] B細胞性リンパ増殖性疾患におけるMYD88 L265P変異
- Author(s)
  山本絵里奈,　冨田章裕. 入山智沙子、島田和之、廣瀬達也、杉山恵亮、水野紘樹、金田典雄、清井仁、直江知樹.
- Organizer
  際75回　日本血液学会学術集会（口演）
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] Mechanism of FLT3 ligand dependent resistance to FLT3 inhibitors
- Author(s)
  陳昉里、石川裕一、直江知樹、清井仁
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場　大阪府　大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] Comprehensive Analysis of Genetic Alterations and Their Prognostic Impacts in Adult Acute Myeloid Leukemia Patients Treated with the Japan Adult Leukemia Study
- Author(s)
  Hitoshi Kiyoi, RiKa Kihara,Yasunobu Nagata, Seishi Ogawa,Tomoki Naoe.
- Organizer
  第5回日本血液学会（JSH)国際シンポジウム
- Place of Presentation
  アクトシティ浜松　コングレスセンター　静岡県　浜松市
- Year and Date
  2014-05-24 – 2014-05-25
- Invited
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] Analysis of rituximab resistance mechanism in CD20 positive B-cell lymphoma cells.
- Author(s)
  島田和之、冨田章裕、徳永隆之、入山智沙子、木下朝博、清井仁、Cragg Mark、直江知樹.
- Organizer
  際75回　日本血液学会学術集会（口演）
- Place of Presentation
  ロイトン札幌（札幌市）
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] 共発現する正常受容体型チロシンキナーゼ（RTK）のリガンド依存性シグナルを介した阻害剤の効果減弱機構
- Author(s)
  鈴木弘太郎、石川裕一、清井　仁
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　神奈川県　横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] Biological and genetic analyses of intravascular large B-cell lymphoma using xenograft mouse model.
- Author(s)
  島田和之、島田聡子、杉本慶樹、早川文彦、片山幸、平川晃弘、中村栄男、瀬戸加大、直江知樹、冨田章裕、清井仁
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Inhibitory effects of FL on proliferation and FLT3 inhibitors in Wt- and ITD-FLT3-co-expressing cells
- Author(s)
  陳昉里、石川裕一、木原里香、清井仁
- Organizer
  第5回日本血液学会（JSH)国際シンポジウム
- Place of Presentation
  アクトシティ浜松　コングレスセンター　静岡県　浜松市
- Year and Date
  2014-05-24 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] PAX5 Tyrosine Phosphorylation By Syk Co-Operatively Works with Its Serine Phosphorylation By ERK1/2 and Cancels PAX5-Dependent Repression of BLIMP1: A Mechanism of Antigen-Triggering Plasma Cell Differentiation through B Cell Receptor Signal.
- Author(s)
  稲垣裕一郎、早川文彦、井本直人、森下喬允、直江知樹、清井仁
- Organizer
  第56回米国血液学会
- Place of Presentation
  Moscone Center （サンフランシスコ、米国）
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] マウスモデルでのPAX5-PMLによる急性リンパ性白血病の解析
- Author(s)
  井本直人、倉橋信悟、早川文彦、安田貴彦、清井　仁
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] 骨髄スメア標本とパイロシークエンス法を用いたB細胞性腫瘍におけるMYD88 L265P変異解析
- Author(s)
  鈴木康裕、冨田章裕、入山智沙子、島田和之、山本絵里奈、金田典雄、清井仁
- Organizer
  第12回日本臨床腫瘍学会総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市博多区）
- Year and Date
  2014-07-17 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] 末梢血cell-free DNAを用いたB細胞リンパ腫における遺伝子変異解析
- Author(s)
  鈴木康裕、冨田章裕、吉田健一、島田和之、入山智沙子、真田昌、白石友一、千葉健一、田中洋子、宮野悟、小川誠司、清井仁
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市西区）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] PAX5-PML Induces Pro B Acute Lymphoblastic Leukemia In Mice
- Author(s)
  井本直人、倉橋信悟、早川文彦、安田貴彦、清井　仁・・・他
- Organizer
  第5回日本血液学会（JSH)国際シンポジウム
- Place of Presentation
  アクトシティ浜松（静岡県浜松市中区）
- Year and Date
  2014-05-24 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Utilization of Peripheral Blood Cell-free DNA for Genetic Analyses in MDS
- Author(s)
  Yasuhiro Suzuki, Akihiro Tomita, Chisako Iriyama, Kazuyuki Shimada, Hitoshi Kiyoi
- Organizer
  第35回国際血液学会議
- Place of Presentation
  China National Convention Center（北京、中国）
- Year and Date
  2014-09-04 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Using peripheral blood circulating DNAs to detect genetic mutations and clonal expansion in MDS.
- Author(s)
  鈴木康裕、冨田章裕、入山智沙子、白幡瑞穂、島田和之、清井仁、直江知樹.
- Organizer
  際75回　日本血液学会学術集会（ポスター）
- Place of Presentation
  ロイトン札幌（札幌市）
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] 活性型変異FLT3を標的とした白血病治療の現状と課題
- Author(s)
  清井仁
- Organizer
  第23回日本Cell Death学会学術集会
- Place of Presentation
  東京医科歯科大学　鈴木章夫記念講堂　東京都　文京区
- Year and Date
  2014-07-18 – 2014-07-19
- Invited
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] Mechanism of FLT3 Ligand Dependent Resistance to FLT3 Inhibitors
- Author(s)
  Fangli Chen,Yuichi Ishikawa,Akimi Akashi,Tomoki Naoe,Hitoshi Kiyoi
- Organizer
  第56回米国血液学会
- Place of Presentation
  サンフランシスコ、米国
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] Mechanism of FLT3 Ligand dependent resistance to FLT3 inhibitors
- Author(s)
  陳昉里、石川裕一、木原里香、直江知樹、清井仁
- Organizer
  第35回国際血液学会
- Place of Presentation
  北京　中国
- Year and Date
  2014-09-04 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-24591387
[Presentation] Clinical and Molecular Significance of Peripheral Blood Cell-Free DNA in B-Cell Lymphomas for Detection of Genetic Mutations and Correlation with Disease Status
- Author(s)
  Yasuhiro Suzuki、Akihiro Tomita、 Kenichi Yoshida、Kazuyuki Shimada、 Chisako Iriyama、Masashi Sanada, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Seishi Ogawa, Hitoshi Kiyoi
- Organizer
  第56回米国血液学会
- Place of Presentation
  Moscone Center （サンフランシスコ、米国）
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Significance of expression of EZH2 mRNA splicing variants in MDS patients.
- Author(s)
  白幡瑞穂、冨田章裕、入山智沙子、鈴木康裕、清井仁、直江知樹.
- Organizer
  際75回　日本血液学会学術集会（口演）
- Place of Presentation
  ロイトン札幌（札幌市）
- Data Source
  KAKENHI-PROJECT-24591388
[Presentation] 末梢血遊離DNAを用いたB細胞リンパ腫における遺伝子変異解析
- Author(s)
  鈴木康裕、冨田章裕、入山智沙子、島田和之、清井仁・・・他
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Development and Analysis of Novel Intravascular Large B-Cell Lymphoma NOD/Shi-Scid IL2R γnull Mouse Xenograft Model.
- Author(s)
  Kazuyuki Shimada, Satoko Shimada, Keiki Sugimoto, Fumihiko Hayakawa, Miyuki Katayama, Akihiro Hirakawa, Yusuke Takagi, Shigeo Nakamura, Masao Seto, Tomoki Naoe, Akihiro Tomita, Hitoshi Kiyoi
- Organizer
  第56回米国血液学会
- Place of Presentation
  Moscone Center （サンフランシスコ、米国）
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-25293218
[]
[]

1. TOMITA Akihiro (80378215)

# of Collaborated Projects: 6 results

# of Collaborated Products: 61 results
2. NAOE Tomoki (50217634)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
3. AOKI Ichio (10319519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HAYAKAWA Fumihiko (30402580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
5. SHIMADA Kazuyuki (50631503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
6. AKAO Yukihiro (00222505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ITO Mamoru (00176364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ABE Akihiro (00432261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MATSUSHITA Tadashi (30314008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 恵美宣彦 (30185144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 石川裕一 (80721092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. SUZUKI Yasuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
13. KATSUMI Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. ITO Yuri

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. YAMAUCHI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. OHTAKE Shigeki

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
17. MIYAZAKI yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
18. SATOU Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. ANDO Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 小川誠司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 川島直実

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 田村彰吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 松村到

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 能浦三奈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 後藤辰徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 通山薫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 上野敏秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 寺倉精太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 安田貴彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
30. 増子正義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 末延聡一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 佐藤聡美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 平尾敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 麻生範雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
35. 小島研介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
36. 佐藤好隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 葉名尻良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 西脇聡史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 浦野健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 村田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kiyoi Hitoshi 清井 仁

KIYOI Hitoshi 清井 仁

Research Projects

Research Products

Co-Researchers

Elucidation and overcoming molecular abnormalities associated with selection and resistance of acute myeloid leukemia clones through the molecularly targeted therapy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular pathologic elucidation to become usefulness and the choice grounds of the novel FLT3 inhibitorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Translational research toward drug discovery of leukemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of ligand dependent resistance mechanism of RTK inhibitorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic and epigenetic abnormalities in malignant lymphoma.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Increase of the target inhibition effects on FLT3 based on the glycosylation and cellular localization statusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

キナーゼ阻害剤感受性パネルに基づく白血病の層別化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of the mechanisms of resistance to monoclonal antibody therapy and exploration of overcoming strategies.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

チロシンキナーゼ阻害剤の至適併用療法を予測するサロゲートマーカーの確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the biojogicel effect of the nudeophcsmin gene mutation on development and progression of leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

チロシンキナーゼ阻害剤の感受性を予測するサロゲートマーカーの確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of Transcription Co-repressor Complexes Involved in Differentiation Block of Leukemia Cells, and Development of a New Molecular Targeting Therapy.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of aberrant signal tansduction in hematological malignancy and development of treatment methods.

Principal Investigator

Project Period (FY)

Kiyoi Hitoshi 清井仁

KIYOI Hitoshi 清井仁