Matsumoto Masahito 松本征仁

… Alternative Names

MATSUMOTO Masahito 松本征仁

松本征仁マツモトマサヒト

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Researcher Number	90321819
Other IDs	https://orcid.org/0000-0002-8445-838X
External Links
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 特任教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 順天堂大学, 大学院医学研究科, 特任教授 2020 – 2021: 東京医科歯科大学, 生体材料工学研究所, 准教授 2018: 順天堂大学, 医学(系)研究科(研究院), 准教授 2018: 順天堂大学, 医学(系)研究科(研究院), 客員准教授 2017: 埼玉医科大学, 医学部, 客員講師 … More 2012 – 2016: 埼玉医科大学, 医学部, 講師 2004 – 2009: 埼玉医科大学, 医学部, 講師 2003: 埼玉医科大学, 医学部, 助手 2001: 埼玉医科大学, 歯学部, 助手 Less
Review Section/Research Field	Principal Investigator Metabolomics / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90120:Biomaterials-related / Digestive surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Orthopaedic surgery / Biological Sciences Except Principal Investigator Basic Section 90120:Biomaterials-related / Biomedical engineering/Biomaterial science and engineering / Regenerative medicine / Surgical dentistry / Orthopaedic surgery
Keywords	Principal Investigator 転写因子 / 破骨細胞 / 1型糖尿病 / 直接変換 / 糖尿病 / 分化転換 / NFATc1 / p38MAPキナーゼ / 細胞分化 / 体細胞 … More / 再生医学 / 分化 / 骨吸収 / RANKL / シグナル伝達 / 膵内分泌細胞 / 自己免疫疾患 / RNA送達 / RNA / 直接分化転換 / ダイレクトリプログラミング / インスリン / ゲノム / 再生 / 膵β細胞 / 遺伝子調節 / Pax6 / エピジェネティクス / ロコモティブ / 骨芽細胞 / エピジェネティック / 糖代謝 / 骨代謝 / 活性酸素 / pax6 / 5-S-GAD / 活性酵素 / MAPキナーゼ / pzx6 / NFATcl / p38MAPK / 造血幹細胞 … More Except Principal Investigator 膵β細胞 / single cell / β細胞 / 破骨細胞 / 骨代謝 / インスリン / 1型糖尿病 / ダイレクトリプログラミング / hiPSダブルノックイン / hiPS / single cell analysis / beta cell / 化合物スクリーニング / iPS細胞 / double KI hiPSC / ケミカルスクリーニング / hiPSレポーター / 膵β細胞分化 / 神経系 / 血管系 / CDK6 / 分化能 / 遊走能 / 遺伝子網羅的解析 / 分化 / ネットワーク / 神経芽細胞 / 骨芽細胞 / ネットワーク機構 / 骨減少症 / 骨・神経・血管 / 血管内皮細胞 / 骨細胞 / semaphorin 3A / netrin-4 / 神経再生 / Pax6 / p38MAPK / 神経科学 / 転写因子 / 酵素 / シグナル伝達 Less

I型糖尿病根治のためヒト膵β細胞の直接分化転換効率を押し上げる遺伝子を見つけ出す
- Principal Investigator
  
  遠藤英樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Juntendo University
ウイルス感染による1型糖尿病の発症機序の解明と自己免疫疾患の普遍性Principal Investigator
- Principal Investigator
  
  松本征仁
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Juntendo University
Development of RNA therapies for curing of type 1 diabetesPrincipal Investigator
- Principal Investigator
  
  Matsumto Masahito
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Juntendo University
  Tokyo Medical and Dental University
Development of oral therapy towards type 1 diabetes and molecular mechanism of cell fate conversion in gut epitheliumPrincipal Investigator
- Principal Investigator
  
  Matsumoto Masahito
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tokyo Medical and Dental University
  Juntendo University
Direct conversion for pancreatic beta cell regeneration towards type 1 diabetesPrincipal Investigator
- Principal Investigator
  
  Matsumoto Masahito
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Juntendo University
  Saitama Medical University
Development and finding the mechanism of pancreatic beta cell differentiation from hiPS cells through Single cell analysis
- Principal Investigator
  
  Sugahara Izumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Center for Global Health and Medicine
  Saitama Medical University
Molecular mechanisms of nerve-vessel-bone network
- Principal Investigator
  
  SATO Tsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Saitama Medical University
Molecular insights of the crosstalk between locomotive and metabolic syndromesPrincipal Investigator
- Principal Investigator
  
  Matsumoto Masahito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical University
Chemical screening of novel factor to promote beta cell differentiation from hiPS cells
- Principal Investigator
  
  Okazaki Yasushi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  Saitama Medical University
Regulatory mechanisms of bone metabolism by nervous system
- Principal Investigator
  
  KATO Naoki
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical University
Self-Control of osteoclasts on bone resorption and mechanism of osteoclast differentiation by a novel drugPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Masahito
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Saitama Medical University
破骨細胞分化におけるMAPキナーゼの階層的分化制御と生体機能の解明Principal Investigator
- Principal Investigator
  
  松本征仁
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Saitama Medical University
遺伝子改変マウスを用いた破骨細胞の骨代謝機能におけるp38MAPキナーゼの生理的役割Principal Investigator
- Principal Investigator
  
  松本征仁
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Saitama Medical University
P38MAPキナーゼを介した造血幹細胞の時系列分化の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  松本征仁
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Saitama Medical University

[Book] ペプチドを利用した糖尿病・骨代謝疾患の機能再建と再生,医療・診断をささえるペプチド科学-再生医療・DDS・診断への応用第V編再生治療第5章2017
- Author(s)
  松本征仁
- Publisher
  (株)シーエムシー出版
- ISBN
  9784781312675
- Data Source
  KAKENHI-PROJECT-16K15624
[Journal Article] A new method for identifying mouse pancreatic ducts2018
- Author(s)
  Nakajima C, Kamimoto K, Miyajima K, Matsumoto M, Okazaki Y, Kobayashi-Hattori K, Shimizu M, Yamane T, Oishi Y, Iwatsuki K.
- Journal Title
  
  Tissue Eng.
  
  Volume: 24 Issue: 8 Pages: 480-485
- DOI
  10.1089/ten.tec.2018.0127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16K15624
[Journal Article] Mobility and biomechanical functions in the aging male : testosterone and the Locomotive Syndrome.2018
- Author(s)
  Fink J, Jackney A, Matsumoto M, Maekawa T, Nkazato K, Horie S.
- Journal Title
  
  Aging Male
  
  Volume: 29 Issue: 5 Pages: 1-8
- DOI
  10.1080/13685538.2018.1504914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16K15624
[Journal Article] Expansion of transplanted islets in mice by co-transplantation with adipose tissue-derived mesenchymal stem cells2018
- Author(s)
  Tanaka Tomoko、Kojima Daibo、Mera Toshiyuki、Matsumoto Masahito、Yasunami Yohichi、Yanase Toshihiko
- Journal Title
  
  Heliyon
  
  Volume: 4 Issue: 5 Pages: e00632-e00632
- DOI
  10.1016/j.heliyon.2018.e00632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09815, KAKENHI-PROJECT-16K15624
[Journal Article] Potential application of testosterone replacement therapy as treatment for obesity and type 2 diabetes in men.2018
- Author(s)
  Fink J, Matsumoto M, Tamura Y.
- Journal Title
  
  Steroids
  
  Volume: 161 Pages: 161-166
- DOI
  10.1016/j.steroids.2018.08.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16K15624
[Journal Article] Anabolic-androgenic steroids: procurement and administration practices of doping athletes2018
- Author(s)
  Fink Julius、Schoenfeld Brad Jon、Hackney Anthony C.、Matsumoto Masahito、Maekawa Takahiro、Nakazato Koichi、Horie Shigeo
- Journal Title
  
  The Physician and Sportsmedicine
  
  Volume: 47 Issue: 1 Pages: 10-14
- DOI
  10.1080/00913847.2018.1526626
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09151, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16K15624
[Journal Article] Netrin-4 Promotes Differentiation and Migration of Osteoblasts2017
- Author(s)
  Enoki Y, Sato T, Kokabu S, Hayashi N, Iwata T, Yamato M, Usui M, Matsumoto M, Tomoda T, Ariyoshi W, Nishihara T, Yoda T
- Journal Title
  
  In vivo
  
  Volume: 31 Pages: 793-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15624
[Journal Article] Differentiation of Islet Progenitors Regulated by Nicotinamide into Transcriptome-Verified β Cells That Ameliorate Diabetes.2017
- Author(s)
  Jiang FX, Li K, Archer M, Mehta M, Jamieson E, Charles A, Dickinson JE, Matsumoto M, Morahan G
- Journal Title
  
  Stem Cells
  
  Volume: 35 Issue: 5 Pages: 1341-1354
- DOI
  10.1002/stem.2567
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15624
[Journal Article] Functional roles of netrin-1 in osteoblast differentiation. In vivo2017
- Author(s)
  Sato M, Kokabu S, Enoki Y, Hayashi N, Matsumoto M, Nakahira M, Sugasawa M, Yoda T
- Journal Title
  
  In vivo
  
  Volume: 31 Pages: 321-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15624
[Journal Article] An inhibitor of Fibroblast Growth Factor Receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2016
- Author(s)
  Yamashita-Sugahara Y, Matsumoto M, Ohtaka M, Nishimura K, Nakanishi M, Mitani K, Okazaki Y
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 335908-335908
- DOI
  10.1038/srep35908
- NAID
  120007129280
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15624, KAKENHI-PROJECT-15K21333
[Journal Article] Involvement of skeletal fragility by teriparatide in adult osteoporosis patients: a novel mechanostat-based hypothesis for bone quality.2015
- Author(s)
  Sugiyama T, Torio T, Sato T, Matsumoto M, Kim YT, Oda H.
- Journal Title
  
  Frontiers in Endocrinol.
  
  Volume: 6 Pages: 6-6
- DOI
  10.3389/fendo.2015.00006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462380
[Journal Article] Donepezil prevents RANK-induced boneloss via inhibitionofosteoclast differentiation by downregulating acetylcholinesterase.2015
- Author(s)
  Sato T, Enoki Y, Sakamoto Y, Yokota K, Okubo M, Matsumoto M, Hayashi N, Usui M, Kokabu S, Mimura T, Nakazato T, Araki N, Fukuda T, Okazaki Y, Suda T, Takeda S, Yoda T.
- Journal Title
  
  Heliyon
  
  Volume: 1 Issue: 1 Pages: 1-20
- DOI
  10.1016/j.heliyon.2015.e00013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462380, KAKENHI-PROJECT-26870543
[Journal Article] Netrin-4 derived from murine vascular endothelial cells inhibits osteoclast differentiation in vitro and prevents bone loss in vivo.2014
- Author(s)
  Matsumoto, Masahiko Okubo, Keisuke Nakashima, Masayuki Yamato, Teruo Okano, Toru Fukuda, Dai Chida, Yuuki Imai, Hisataka Yasuda, Tatsuji Nishihara, Masumi Akita, Hiromi Oda, Yasushi Okazaki, Tatsuo Suda, Tetsuya Yoda
- Journal Title
  
  FEBS Lett.
  
  Volume: 588 Issue: 14 Pages: 2262-2269
- DOI
  10.1016/j.febslet.2014.05.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25253090, KAKENHI-PROJECT-26293432
[Journal Article] Family with sequence familarity 57, member B (Fam57b), a novel peroxisome proliferator-activated receptor g target gene that regulates adipogenesis through ceramide synthesis.2013
- Author(s)
  Yamashita-Sugahara Y., Tokuzawa, Y., Nakachi, Y., Knesaki-Yatsuka, Y., Matsumoto, M., Mizuno, Y., Okazaki, Y.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 7 Pages: 4522-4537
- DOI
  10.1074/jbc.m112.440792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462380
[Journal Article] The Paired-box Domain Transcription Factor Pax6 Binds to the Upstream Region of the TRAP Gene Promoter and Suppresses RANKL-induced Osteoclast Differentiation2013
- Author(s)
  Kogawa M, Hisatake K, Atkins GJ, Findlay DM, Enoki Y, Sato T, Gray PC, Kanesaki-Yatsuka Y, Anerson PH, Wada S, Kato N, Fukuda A, Katayama S, Tsujimoto M, Yoda T, Suda T, Okazaki Y, Matsumoto M
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 43 Pages: 31299-31312
- DOI
  10.1074/jbc.m113.461848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460354, KAKENHI-PROJECT-25462380
[Journal Article] Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo2013
- Author(s)
  Kato N、Matsumoto M、Kogawa M、Atkins GJ、Findlay DM、Fujikawa T、Oda H、Ogata M
- Journal Title
  
  J. Neuroinflammation
  
  Volume: 10(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo2013
- Author(s)
  Kato, N., Matsumoto, M., Kogawa, M., Atkins, G.J., Findlay, D.M., Fujikawa, T., Oda, H., and Ogata, M.
- Journal Title
  
  Journal of neuroinflammation
  
  Volume: 10 Issue: 1 Pages: 1-1
- DOI
  10.1186/1742-2094-10-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590567, KAKENHI-PROJECT-25462380
[Journal Article] 生体内における p38 MAPK を介した神経再生制御機構(第2 報)2010
- Author(s)
  加藤直樹、松本征仁、緒方正人、禾泰壽、織田弘美
- Journal Title
  
  日本手外科学会雑誌
  
  Volume: 27(1)
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] 個体レベルにおける p38 MAPK の神経再生への関与2010
- Author(s)
  加藤直樹、松本征仁、緒方正人、禾泰壽、酒井宏哉、織田弘美
- Journal Title
  
  第2 報、末梢神経
  
  Volume: 21(2) Pages: 320-321
- NAID
  10027267954
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] p38MAPKシグナル伝達阻害により神経再生は遅延する:変異型p38ノックインマウスを用いた知見2010
- Author(s)
  加藤直樹、松本征仁、緒方正人、禾泰壽、織田弘美
- Journal Title
  
  末梢神経 21(1)
  
  Pages: 84-90
- NAID
  10027578674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] 個体レベルにおけるp38MAPKの神経再生への関与2010
- Author(s)
  加藤直樹、松本征仁、緒方正人、禾泰壽、酒井宏哉、織田弘美
- Journal Title
  
  第2報、末梢神経 21(2)
  
  Pages: 20-321
- NAID
  10027267954
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] p38 MAPK シグナル伝達阻害により神経再生は遅延する:変異型 p38 ノックインマウスを用いた知見2010
- Author(s)
  加藤直樹、松本征仁、緒方正人、禾泰壽、織田弘美
- Journal Title
  
  末梢神経
  
  Volume: 21(1) Pages: 84-90
- NAID
  10027578674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] 生体内におけるp38MAPKを介した神経再生制御機構(第2報)2010
- Author(s)
  加藤直樹、松本征仁、緒方正人、禾泰壽、織田弘美
- Journal Title
  
  日本手外科学会雑誌 27(1)
  
  Pages: 276-276
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] 個体レベルにおけるp38MAPKの神経再生への関与2009
- Author(s)
  加藤直樹、松本征仁、緒方正人、禾泰壽、織田弘美
- Journal Title
  
  末梢神経 20(2)
  
  Pages: 174-175
- NAID
  10027267954
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] 個体レベルにおけるp38 MAPKの神経再生への関与2009
- Author(s)
  加藤直樹, 松本征仁, 緒方正人, 禾泰壽, 織田弘美
- Journal Title
  
  末梢神経 20
  
  Pages: 174-175
- NAID
  10027267954
- Data Source
  KAKENHI-PROJECT-19790637
[Journal Article] 生体内におけるp38MAPKを介した神経再生制御機構:遺伝子マウスを用いた固体レベルでの検討2009
- Author(s)
  加藤直樹、松本征仁、緒方正人、禾泰壽、織田弘美
- Journal Title
  
  日本手外科学会雑誌 26(1)
  
  Pages: 298-298
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] 個体レベルにおける p38 MAPK の神経再生への関与2009
- Author(s)
  加藤直樹、松本征仁、緒方正人、禾泰壽、織田弘美
- Journal Title
  
  末梢神経
  
  Volume: 20(2) Pages: 174-175
- NAID
  10027267954
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] Cytokine-dependent modification of IL-12p70 and IL-23 balance in dendritic cells by ligand activation of V{alpha}24 invariant NKT cells.2009
- Author(s)
  Uemura, Y., Liu, T.Y., Narita, Y.,Suzuki, M., Nakatsuka, R., Araki, TMatsumoto,M.,Iwai,L.K.,Hirasawa, N.,Matsuoka, Y., Murakami, M., Kimura,T., Hase, M., Kohno, H., Sasaki, Y.,Ichihara, Y., Ichihara, O., Kikuchi,H., Sakamoto, Y., Jiao, S.C., Senju,S., Sonoda,Y.
- Journal Title
  
  J. Immunol. 183
  
  Pages: 201-208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790637
[Journal Article] PIAS3 negatively regulates the RANKL -mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts.2009
- Author(s)
  Hikata, T., Takaishi, H., Takito, J., Furukawa, M., Uchikawa, S., Kimura, T., Okada, Y, Matsumoto, M., et al.
- Journal Title
  
  Blood 113
  
  Pages: 2202-2212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790637
[Journal Article] 生体内における p38 MAPK を介した神経再生制御機構:遺伝子マウスを用いた固体レベルでの検討2009
- Author(s)
  加藤直樹、松本征仁、緒方正人、禾泰壽、織田弘美
- Journal Title
  
  日本手外科学会雑誌
  
  Volume: 26(1)
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] 遺伝子組み換えマウスを用いたp38MAPKの神経再生制御機構に関する新たな知見2008
- Author(s)
  加藤直樹、松本征仁、緒方正人、関川三四子、禾泰壽、織田弘美
- Journal Title
  
  末梢神経 19(2)
  
  Pages: 398-398
- NAID
  10025625685
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] 遺伝子組み換えマウスを用いた p38 MAPK の神経再生制御機構に関する新たな知見2008
- Author(s)
  加藤直樹、松本征仁、緒方正人、関川三四子、禾泰壽、織田弘美
- Journal Title
  
  末梢神経
  
  Volume: 19(2) Pages: 398-398
- NAID
  10025625685
- Data Source
  KAKENHI-PROJECT-20591790
[Journal Article] 遺伝子組み換えマウスを用いたp38 MAPKの神経再生制御機構に関する新たな知見2008
- Author(s)
  加藤直樹, 松本征仁, 緒方正人, 関川三四子, 禾泰壽, 織田弘美
- Journal Title
  
  末梢神経 19
  
  Pages: 398-398
- NAID
  10025625685
- Data Source
  KAKENHI-PROJECT-19790637
[Journal Article] p38MAPキナーゼを介した破骨細胞の分化段階的制御2007
- Author(s)
  松本征仁
- Journal Title
  
  生化学 79・2
  
  Pages: 140-144
- NAID
  10018733620
- Data Source
  KAKENHI-PROJECT-17790612
[Journal Article] The Fission Yeast Protein Kerlp Is an Ortholog of RNA Polymerase I Subunit A14 in Saccharomyces cerevisiae and Is Required for Stable Association of Rrn3p and RPA22005
- Author(s)
  Imazawa Y, Hisatake K, Mitsuzawa H, Matsumoto M, (他6名)
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 11467-11474
- Data Source
  KAKENHI-PROJECT-15790469
[Journal Article] A transcriptional coactivotor PC4 stimulates promoter escape and facilitates a high level of transcription activation by GAL4-VP16.2004
- Author(s)
  Fukuda A., Nakadai, T., Shimada, M., Tsukui, T., Matsumoto, M., (他3名)
- Journal Title
  
  Mol.Cell.Biol. 24
  
  Pages: 6525-6535
- Data Source
  KAKENHI-PROJECT-15790469
[Journal Article] Essential role of p38 MAP Kinase in Cathepsin K Gene Expression during Osteoclastogenesis through Association of NFATc1 and PU.1.2004
- Author(s)
  Matsumoto, M., Kogawa, M., Wada, S., (他5名)
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 45969-45979
- Data Source
  KAKENHI-PROJECT-15790469
[Patent] 膵内分泌細胞の分化促進と産生法の迅速効率化、および糖尿病治療薬スクリーニング2016
- Inventor(s)
  松本征仁、岡﨑康司、菅原泉
- Industrial Property Rights Holder
  松本征仁、岡﨑康司、菅原泉
- Industrial Property Rights Type
  特許
- Filing Date
  2016-10-28
- Overseas
- Data Source
  KAKENHI-PROJECT-16K15624
[Patent] 膵内分泌細胞及びその製造方法、並びに分化転換剤2015
- Inventor(s)
  松本征仁、岡﨑康司、菅原泉
- Industrial Property Rights Holder
  松本征仁、岡﨑康司、菅原泉
- Industrial Property Rights Type
  特許
- Filing Date
  2015-07-03
- Overseas
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] 細胞分化と直接変換による細胞運命決定のコントロール2019
- Author(s)
  松本征仁　岡﨑康司
- Organizer
  H30年度先端モデル動物支援プラットフォーム成果発表会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15624
[Presentation] 低血糖に陥らないヒトバイオ人工膵島の革新的作出法と安全性評価2019
- Author(s)
  松本征仁　岡﨑康司
- Organizer
  AMED橋渡し研究戦略的推進プログラム成果発表会
- Data Source
  KAKENHI-PROJECT-16K15624
[Presentation] 腸管オルガノイドと生体腸組織における内分泌細胞の比較2019
- Author(s)
  大木淳子, 坂下陽彦, 稲葉明彦, 粟飯原永太郎, 内山博允, 松本征仁, 二ノ宮裕三, 山根拓実, 大石祐一, 岩槻健
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-16K15624
[Presentation] in vivo / in vitro双方からの膵臓再生メカニズムの解明2018
- Author(s)
  中嶋ちえみ, 神元健児, 美谷島克宏, 松本征仁 ,岡崎康司, 山根拓実, 岩槻健, 大石祐一
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K15624
[Presentation] 成熟膵島で抑制されている遺伝子の解析2018
- Author(s)
  西村渉, 安田和基, 松本征仁, 岡崎康司, 野田泰子
- Organizer
  第61回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-16K15624
[Presentation] FGFR1阻害剤は膵内分泌前駆細胞（NGN3+)から内分泌細胞への分化を促進する2017
- Author(s)
  Yzumi Yamashita-Sugahara, Masahito Matsumoto,Manami Ohtaka,Ken Nishimura Mahito Nakanishi,Kohnosuke Mitani & Yasushi Okazaki
- Organizer
  2016日本再生医療学会
- Place of Presentation
  仙台
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15K21333
[Presentation] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017
- Author(s)
  Yzumi Yamashita-Sugahara, Masahito Matsumoto,Manami Ohtaka,Ken Nishimura Mahito Nakanishi,Kohnosuke Mitani & Yasushi Okazaki
- Organizer
  2017 Miami winter Symposium: Diabetes
- Place of Presentation
  Miami
- Year and Date
  2017-01-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21333
[Presentation] ovel approaches for making beta cells towards beta cell replenishment therapy2017
- Author(s)
  Matsumoto M
- Organizer
  Kyoto Diabetes Mini-symposium-Beta cell replacement strategies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15624
[Presentation] ダイレクトリプログラミングによる体細胞からβ細胞の高効率作出法2016
- Author(s)
  松本征仁
- Organizer
  日本IDDMネットワークサイエンスフォーラム
- Place of Presentation
  佐賀県鳥栖市
- Year and Date
  2016-06-25
- Invited
- Data Source
  KAKENHI-PROJECT-16K15624
[Presentation] DNAのメチル化を介した骨芽細胞分化のエピジェネティクス制御2015
- Author(s)
  大久保正彦, 松本征仁, 榎木祐一郎, 佐藤毅, 須田立雄, 岡﨑康司, 依田哲也
- Organizer
  第33回日本骨代謝学会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-07-22
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] Epigenetic control of osteoblast differentiation via DNA methylation2015
- Author(s)
  Okubo M., Matsumoto M, Mizuno Y, Sato T, Yoda T, Okazaki Y.
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] Insulin promoter-Venus/NGN3 promoter-mCherry ダブルノックインhiPS細胞を用いたβ細胞分化誘導の解析2015
- Author(s)
  菅原　泉, 松村瞭、佐藤達也、松谷智子、相澤絵美、岩長ゆずる、松本征仁、三谷幸之介、岡崎康司
- Organizer
  第13回RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉医科大学　創立30周年記念講堂　(埼玉県　日高市）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25505003
[Presentation] アセチルコリンエステラーゼ阻害剤であるドネペジルは、破骨細胞の形成と機能を強力に抑制し、RANKL誘導性の急速な骨量減少を防止する2015
- Author(s)
  佐藤毅、大久保正彦、榎木祐一郎、古株彰一郎、松本征仁、杉山聡宏、依田哲也
- Organizer
  第33回日本骨代謝学会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-07-22
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] 新たな破骨細胞分化抑制因子としてのPax6の機能解析2015
- Author(s)
  大久保正彦, 松本征仁, 甲川昌和, 八塚由紀子, 榎木祐一郎, 佐藤毅, 片山茂裕, 須田立雄, 岡﨑康司, 依田哲也
- Organizer
  第69回日本口腔科学会学術集会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] Vascular endothelial cells inhibit osteoclastogenesis by netrin 4 through DSCAM receptor2013
- Author(s)
  Enoki, Y., Sato, T., Kokabu, S., Okubo, M., Iwata, T., Usui, M., Fukuda, T., Takeda, S, Matsumoto, M., Yoda, T.
- Organizer
  ASBMR
- Place of Presentation
  Maryland USA
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] Self-limiting system of osteoclast differentiation by the Paired-box Domain Transcription factor Pax62013
- Author(s)
  Masahito Matsumoto, Masakazu Kogawa, Koji Hisatake, Gerald J. Atkins, David M. Findlay, Yuichiro Enoki, Tsuyoshi Sato, Peter C. Gray8, Yukiko Kanesaki-Yatsuka5, Paul H. Anderson9, Seiki Wada2, Naoki Kato4, Aya Fukuda1,7, Shigehiro Katayama, Masafumi Tsujimoto, Tetsuya Yoda, Tatsuo Suda, Yasushi Okazaki
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] Dual functional roles of Pax6 in the regulation of bone and glucose metabolism Osteoclast Differentiation.2013
- Author(s)
  Kogawa, M., Hisatake, K., Atkins, G.J., Findlay, D.M., Enoki, Y., Sato, Tsuyoshi, Gray, P, Wada, S., Kato, N., Fukuda, A., Katayama, S., Tsujimoto, M., Yoda, T., Suda, T., Okazaki, Y., and Matsumoto, M.
- Organizer
  ASBMR
- Place of Presentation
  Maryland USA
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] ヒトiPS細胞におけるヘルパー依存型アデノウィルスを用いたInsulin promoter-Venusレポーター細胞の作製とその解析2013
- Author(s)
  菅原泉　松村瞭、佐藤達也、松谷智子、相澤絵美、岩長ゆずる、松本征仁、三谷幸之介、岡崎康司
- Organizer
  第11回 RCGMシンポジウム
- Place of Presentation
  埼玉日高市
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] Involvement of acetylcholinesterase in osteoclast differentiation.2013
- Author(s)
  Enoki, Y., Sato, T., Kokabu, S., Okubo, M., Iwata, T., Usui, M., Fukuda, T., Takeda, S, Matsumoto, M., Yoda, T.
- Organizer
  IBMS
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] 生体内のp38 MAPKの酵素を介したシグナル伝達経路に神経再生制御因子が存在する2011
- Author(s)
  加藤直樹, 松本征仁, 緒方正人, 禾泰壽, 酒井宏哉, 織田弘美
- Organizer
  第22回日本末梢神経学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-20591790
[Presentation] 遺伝子組み換えマウスを用いたp38MAPKの神経再生制御機構に関する新たな知見2008
- Author(s)
  加藤直樹, 松本征仁, 緒方正人, 禾泰壽, 織田弘美
- Organizer
  第19回日本末梢神経学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19790637
[Presentation] 変異型p38ノックインマウスを用いた骨代謝におけるp38MAPKの関与2008
- Author(s)
  加藤直樹, 緒方正人, 禾泰壽, 織田弘美, 松本征仁
- Organizer
  第26回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19790637
[Presentation] 新規破骨細胞分化阻害剤5-s-GADの作用機序2007
- Author(s)
  松本征仁
- Organizer
  第25回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-19790637
[Presentation] PIAS3はRANKL刺激による破骨細胞形成を抑制する2007
- Author(s)
  日方智宏、高石官成、松本征仁、高柳広、浅原弘嗣、戸山芳昭
- Organizer
  第25回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19790637
[Presentation] 新規薬剤5-S-GADの破骨細胞に対する骨吸収抑制機構2007
- Author(s)
  加藤直樹, 甲川昌和, 秋山伸子, 和田誠基, 辻本雅文, 織田弘美, 禾泰壽, 松本征仁
- Organizer
  第25回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19790637
[Presentation] 新規破骨細胞分化阻害剤5-s-GADの作用機序2007
- Author(s)
  甲川昌和, 秋山伸子, 和田誠基, 住本英樹, 禾泰壽, 辻本雅文, 松本征仁
- Organizer
  第25回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19790637
[Presentation] 新規薬剤5-S-GADは破骨細胞の骨吸収を抑制する2007
- Author(s)
  加藤直樹, 甲川昌和, 秋山伸子, 和田誠基, 辻本雅文, 禾泰壽, 織田弘美, 松本征仁
- Organizer
  第22回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19790637
[Presentation] 新規薬剤による破骨細胞の分化の制御2007
- Author(s)
  甲川昌和, 加藤直樹, 秋山伸子, 和田誠基, 辻本雅文, 禾泰壽, 松本征仁
- Organizer
  第22回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19790637

1. OKAZAKI YASUSHI (80280733)

# of Collaborated Projects: 6 results

# of Collaborated Products: 14 results
2. SUGAHARA IZUMI (10633000)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. NAKACHI YUTAKA (10522097)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. SUDA TATSUO (90014034)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. YASUNAMI YOICHI (00166521)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SATO TSUYOSHI (60406494)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
7. KATO Naoki (90448895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
8. ODA Hiromi (60101698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
9. NISHIHARA Tatsuji (80192251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YODA Testuya (60242210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Watanabe Ami (40611421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Nikaido Itoshi (00383290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 辻本雅文 (00281668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 須藤龍彦 (30260227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 久武幸司 (70271236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 臼井通彦 (10453630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 竹田秀 (30376727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 水野洋介 (30406532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 古株彰一郎 (30448899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 位高啓史 (60292926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 小池智 (30195630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 遠藤英樹 (60767169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. HATTORI Satoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. HORIE Shigeo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 小林和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 井本正哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 田中智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 柳瀬敏彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 緒方正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsumoto Masahito 松本 征仁

MATSUMOTO Masahito 松本 征仁

松本 征仁 マツモト マサヒト

Research Projects

Research Products

Co-Researchers

I型糖尿病根治のためヒト膵β細胞の直接分化転換効率を押し上げる遺伝子を見つけ出す

Principal Investigator

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ウイルス感染による1型糖尿病の発症機序の解明と自己免疫疾患の普遍性Principal Investigator

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Development of RNA therapies for curing of type 1 diabetesPrincipal Investigator

Principal Investigator

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Review Section

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Development of oral therapy towards type 1 diabetes and molecular mechanism of cell fate conversion in gut epitheliumPrincipal Investigator

Principal Investigator

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Review Section

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Direct conversion for pancreatic beta cell regeneration towards type 1 diabetesPrincipal Investigator

Principal Investigator

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Development and finding the mechanism of pancreatic beta cell differentiation from hiPS cells through Single cell analysis

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Molecular mechanisms of nerve-vessel-bone network

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Molecular insights of the crosstalk between locomotive and metabolic syndromesPrincipal Investigator

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Chemical screening of novel factor to promote beta cell differentiation from hiPS cells

Principal Investigator

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Regulatory mechanisms of bone metabolism by nervous system

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Self-Control of osteoclasts on bone resorption and mechanism of osteoclast differentiation by a novel drugPrincipal Investigator

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破骨細胞分化におけるMAPキナーゼの階層的分化制御と生体機能の解明Principal Investigator

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遺伝子改変マウスを用いた破骨細胞の骨代謝機能におけるp38MAPキナーゼの生理的役割Principal Investigator

Principal Investigator

Matsumoto Masahito 松本征仁

MATSUMOTO Masahito 松本征仁

松本征仁マツモトマサヒト

[Book] ペプチドを利用した糖尿病・骨代謝疾患の機能再建と再生,医療・診断をささえるペプチド科学-再生医療・DDS・診断への応用第V編再生治療第5章2017