Kobune Masayoshi 小船雅義

… Alternative Names

KOBUNE Masayoshi 小船雅義

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Researcher Number	90336389
Other IDs
External Links
Affiliation (Current)	2025: 札幌医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 札幌医科大学, 医学部, 教授 2009 – 2017: Sapporo Medical University, 医学部, 准教授 2007 – 2008: Sapporo Medical University, 医学部, 講師 2003 – 2006: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Hematology / Gastroenterology / Basic Section 59040:Nutrition science and health science-related / Basic Section 54010:Hematology and medical oncology-related / Tumor therapeutics / Biological Sciences
Keywords	Principal Investigator 骨髄異形成症候群 / 白血病 / 急性骨髄性白血病 / 細胞外小胞 / 白血病幹細胞 / PCBP1 / マイクロRNA / エクソソーム / CXCR4 / MDS … More / 骨髄間質細胞 / 骨髄微細環境 / PTH２R / TIP39 / オートファジー / 神経ペプチド / PTH2R / 骨髄リプログラミング / リプログラミング / PD-MSC / YAP1 / iPS細胞 / STK4 / HIPPO / miR-7977 / 骨髄間葉系幹細胞 / 骨髄間質 / 間葉系幹細胞 / エキソソーム / Hematopoietic stem cell / CD34 negative cell / stromal cell / cord Blood / 造血幹細胞 / CD34陰性細胞 / ストローマ / 臍帯血 / 腫瘍幹細胞 / ゲノム / 予後因子 / 活性酸素 / HPLC-ECD / 幹細胞 / 鉄キレート剤 / 酸化的DNA損傷 / 鉄キレート / 8-OHdG / 発現制御 / 臨床 / シグナル伝達 / 内科 / 癌 / 薬剤耐性 / Rhoシグナル / Wnt / 骨髄腫 / 造血幹細胞増幅 / ストローマ細胞 / インディアン・ヘッジホッグ … More Except Principal Investigator 8-OH-dG / ChIP assay / 多発性骨髄腫 / 急性骨髄性白血病 / 酸化的DNA損傷 / 肝発癌 / C型肝炎 / 腸管機能モニタリング / 栄養療法 / 腸管粘膜障害 / がん化学療法 / 腸内細菌叢 / ジアミンオキシダーゼ / 神経ペプチド / BH3 profiling / 高次元サイトメトリー法 / 高次元サイトメトリー / Treg / GVHD / DPP / DPP8/9 / Iron / Comprehensive analysis / Genome / Hepatocarcinogenesis / Oxidative DNA damage / Chronic Hepatitis C / 鉄 / 8-OHdG / 網羅的解析 / ゲノム / BCL9 / 造血幹細胞 / リンパ球増幅 / フコース / ナノキャリア / 細胞標的療法 / 白血病 / DDS / fucose / AML / 治療 / mTOR / オートファジー / リンパ腫 / (2)糖鎖 / (1)癌 / 内科 / 糖鎖 / 癌 / DNA修復酵素 / DNA修復酸素 / SNP / Mutyh / Ogg1 / 肝細胞癌 / 酸化的DNA傷害 / 慢性肝炎 Less

骨髄微細環境における神経－白血病系の解析
- Principal Investigator
  
  堀口拓人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Sapporo Medical University
がん化学療法時の栄養状態に関わる腸管機能モニタリングの確立
- Principal Investigator
  
  井山諭
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Sapporo Medical University
Development of new therapy for AML by targeting of neuropeptide-PTH2R systemPrincipal Investigator
- Principal Investigator
  
  小船雅義
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Sapporo Medical University
Analysis of the development and pathogenesis of AML/MDS via extracellular vesiclesPrincipal Investigator
- Principal Investigator
  
  Kobune Masayoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Sapporo Medical University
Efficacy for treating MM with DPP8/9 inhibitor.
- Principal Investigator
  
  Iyama Satoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Sapporo Medical University
The effect of exosomal miRNA on AML/MDS stromal cellsPrincipal Investigator
- Principal Investigator
  
  Kobune Masayoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Comprehensive analysis of GVHD regulated cells by high dimensional cytometry and identification of prognostic factors
- Principal Investigator
  
  Murase Kazuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Identifing novel therapeutic target molecules in multiple myeloma using BCL9-ChIPSeq
- Principal Investigator
  
  Takada Kohichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Cell targeting therapy for acute myeloid leukemia
- Principal Investigator
  
  TAKIMOTO Rishu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Development of the lymphocyte in vitro amplification method using HHIP KO stromal cells.
- Principal Investigator
  
  IYAMA Satoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Establishment of iron chelation therapy to inhibit the development of MDSPrincipal Investigator
- Principal Investigator
  
  KOBUNE Masayoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Development of mTOR-targeted novel therapy inducing autophagy for B-cell lymphoma
- Principal Investigator
  
  SATO Tsutomu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Targeting anticancer drug delivery to pancreatic cancer cells using a fucose-bound nanoparticle approach
- Principal Investigator
  
  KATO Junji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Development of dual targeting therapy for cancer stem cells and nichePrincipal Investigator
- Principal Investigator
  
  KOBUNE Masayoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Analyze of DNA repair gene in carcinogenesis from chronic hepatitis C
- Principal Investigator
  
  KATO Junji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Cell adhesion-mediated drug resistance of myeloma cells via Wnt/Rho signaling pathwayPrincipal Investigator
- Principal Investigator
  
  MASAYOSHI Kobune
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
慢性炎症および鉄過剰で誘導される肝発がん機構の解明とその防御
- Principal Investigator
  
  KATO Junji
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
ANALYSYS OF GENES INVOLVED IN OXIDATIVE DNA DAMAGE IN PATIENTS WITH HEPATITIS C
- Principal Investigator
  
  KATO Junji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Ex vivo expansion of human cord blood Lin-CD34-cells using indian hedgehog stromal cellsPrincipal Investigator
- Principal Investigator
  
  KOBUNE Masayoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
Hedgehog/hTERT遺伝子導入不死化ストローマ細胞を用いた造血幹細胞増殖Principal Investigator
- Principal Investigator
  
  小船雅義
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University

[Book] 血液疾患．鉄欠乏性貧血　今日の治療指針　2023年版2023
- Author(s)
  小船雅義．編集者：福井次矢、高木誠、小室一成
- Total Pages
  2192
- Publisher
  医学書院
- ISBN
  9784260050357
- Data Source
  KAKENHI-PROJECT-22K08509
[Book] 血液疾患．鉄欠乏性貧血Iron Deficiency Anemia (IDA)．今日の治療指針　2023年版2023
- Author(s)
  小船雅義
- Total Pages
  2192
- Publisher
  医学書院
- ISBN
  9784260050357
- Data Source
  KAKENHI-PROJECT-22K08509
[Book] 今日の治療指針2015：鉄欠乏性貧血2015
- Author(s)
  小船雅義
- Total Pages
  4
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-15K09482
[Book] 今日の診断指針2015：鉄欠乏性貧血2015
- Author(s)
  小船雅義
- Total Pages
  2
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-15K09482
[Book] 主な血液疾患用薬剤の作用機序と適応.鉄剤・ビタミンB122011
- Author(s)
  小船雅義、加藤淳二
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21591213
[Book] 血液疾患アプローチのための解剖生理.病気と薬パーフェクトガイド増刊号2011
- Author(s)
  小船雅義, 加藤淳二
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-21591213
[Book] 感染・血液診療エキスパート-貧血-炎症に伴う貧血2010
- Author(s)
  小船雅義、加藤淳二
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21591213
[Book] 主な血液疾患用薬剤の作用機序と適応鉄剤・ビタミンB122010
- Author(s)
  小船雅義
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21591213
[Book] 感染・血液診療エキスパート貧血-炎症に伴う貧血2010
- Author(s)
  小船雅義
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21591213
[Book] 血液疾患アプローチのための解剖生理病気と薬パーフェクトBOOK20102010
- Author(s)
  小船雅義
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-21591213
[Book] 主な血液疾患用薬剤の作用機序と適応鉄剤・ビタミン2010
- Author(s)
  小船雅義、加藤淳二
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21591213
[Book] 貧血治療指針2008. IIIエビデンスからみた鉄剤適正使用のための指針-鉄の生理作用と過剰鉄による臓器障害2009
- Author(s)
  加藤淳二, 小船雅義
- Publisher
  札幌 : 響文社
- Data Source
  KAKENHI-PROJECT-19591124
[Book] 血液疾患アプローチのための解剖生理.病気と薬パーフェクトBOOK20092009
- Author(s)
  小船雅義, 加藤淳二
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-21591213
[Book] 血液疾患アプローチのための解剖生理 [病気と薬パーフェクトガイド3 月増刊号病気と薬パーフェクトBOOK 20082008
- Author(s)
  小船雅義、加藤淳二
- Publisher
  東京 : 南山堂
- Data Source
  KAKENHI-PROJECT-19591124
[Book] 血液疾患アプローチのための解剖生理 [病気と薬パーフェクトガイド3月増刊号病気と薬パーフェクトBOOK 20082008
- Author(s)
  小船雅義ら
- Total Pages
  4
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-19591124
[Book] 第2章1鉄過剰症の病態と診断, 総論. 堀田知光、押味和夫監修. Iron Overload鉄キレート療法2007
- Author(s)
  小船雅義, 新津洋司郎
- Publisher
  東京 : メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19591124
[Book] 第1章4鉄代謝の病態生理, フェリチン. 堀田知光、押味和夫監修. Iron Overload鉄キレート療法2007
- Author(s)
  小船雅義, 加藤淳二, 新津洋司郎
- Publisher
  東京 : メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19591124
[Book] 再生医療のためのゲノム操作「間葉系幹細胞のゲノム操作 : Effective genetic modification of mesenchymal stem cells」ゲノム医学2007
- Author(s)
  小船雅義, 新津洋司郎
- Total Pages
  70
- Publisher
  メディカルレビュー社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591003
[Book] 三輪血液病学2005
- Author(s)
  新津洋司郎, 小船雅義
- Total Pages
  17
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-17591003
[Book] ヒト間葉系幹細胞の不死化と再生医療への応用2004
- Author(s)
  小船雅義
- Total Pages
  5
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-15790496
[Journal Article] Gap junction beta‐4 accelerates cell cycle progression and metastasis through MET?AKT activation in pancreatic cancer2024
- Author(s)
  Muramatsu Joji、Arihara Yohei、Yoshida Makoto、Kubo Tomohiro、Nakamura Hajime、Ishikawa Kazuma、Fujita Hiromi、Sugita Shintaro、Konno Takumi、Kojima Takashi、Kawano Yutaka、Kobune Masayoshi、Takada Kohichi
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 5 Pages: 1564-1575
- DOI
  10.1111/cas.16101
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080, KAKENHI-PROJECT-22K08509
[Journal Article] High-grade B-cell lymphoma, not otherwise specified, presenting as primary peritoneal lymphomatosis and successfully treated with dose-adjusted EPOCH-R2024
- Author(s)
  Fujimi Akihito、Nagamachi Yasuhiro、Yamauchi Naofumi、Onoyama Naoki、Hayasaka Naotaka、Matsuno Teppei、Koike Kazuhiko、Goto Yoshiro、Ihara Kohji、Kato Junji、Nishisato Takuji、Kawase Hiroshi、Yano Tomoyuki、Kanaseki Takayuki、Sugita Shintaro、Kobune Masayoshi
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 64 Issue: 1 Pages: 37-44
- DOI
  10.3960/jslrt.23044
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15047, KAKENHI-PROJECT-22K08509
[Journal Article] Successful Treatment With Venetoclax Plus Azacytidine Combined With Radiation Therapy and Donor Lymphocyte Infusion in a Patient With Extramedullary Relapse of Acute Myeloid Leukemia After Stem Cell Transplantation2024
- Author(s)
  Shirato Shotaro、Iyama Satoshi、Fujimi Akihito、Takahashi Satoshi、Kobune Masayoshi
- Journal Title
  
  Cureus
  
  Volume: 16
- DOI
  10.7759/cureus.53655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08509
[Journal Article] Multiple Myeloma with Hyperammonemia Treated with Novel Agents: A Case Series of Three Patients2023
- Author(s)
  Nakamura Hajime、Takada Kohichi、Murase Kazuyuki、Ikeda Hiroshi、Iyama Satoshi、Manabe Tatsuo、Kobune Masayoshi
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 5 Pages: 775-778
- DOI
  10.2169/internalmedicine.0010-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-03-01
- Language
  English
- Data Source
  KAKENHI-PROJECT-22K08509
[Journal Article] Adherence of denosumab treatment for low bone mineral density in Japanese people living with HIV: a retrospective observational study2023
- Author(s)
  Kunimoto Yusuke、Matamura Ryosuke、Ikeda Hiroshi、Horiguchi Hiroto、Fujii Satoshi、Kobune Masayoshi、Fukudo Masahide、Toda Takaki
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 9 Issue: 1 Pages: 45-45
- DOI
  10.1186/s40780-023-00315-9
- Data Source
  KAKENHI-PROJECT-22K08509
[Journal Article] Acute Abdomen and Adrenal Swelling as the First Manifestations of TAFRO Syndrome2023
- Author(s)
  Fujimi Akihito、Nagamachi Yasuhiro、Yamauchi Naofumi、Onoyama Naoki、Matsuno Teppei、Miyajima Naoya、Koike Kazuhiko、Goto Yoshiro、Ihara Kohji、Nishisato Takuji、Kobune Masayoshi
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 11 Pages: 1675-1681
- DOI
  10.2169/internalmedicine.0267-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-06-01
- Language
  English
- Data Source
  KAKENHI-PROJECT-22K08509
[Journal Article] Diagnosis and treatment of anemia by malnutrition in the elderly2023
- Author(s)
  小船雅義
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 64 Issue: 9 Pages: 900-907
- DOI
  10.11406/rinketsu.64.900
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08509
[Journal Article] MUTYH is associated with hepatocarcinogenesis in a non-alcoholic steatohepatitis mouse model2021
- Author(s)
  Sakamoto Hiroki、Miyanishi Koji、Tanaka Shingo、Ito Ryo、Hamaguchi Kota、Sakurada Akira、Sato Masanori、Kubo Tomohiro、Osuga Takahiro、Murase Kazuyuki、Takada Kohichi、Nakabeppu Yusaku、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-83138-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08397, KAKENHI-PROJECT-19K08871, KAKENHI-PROJECT-19K17405, KAKENHI-PROJECT-21K08011
[Journal Article] Six-transmembrane epithelial antigen of the prostate 1 accelerates cell proliferation by targeting c-Myc in liver cancer cells2021
- Author(s)
  Iijima Kazutaka、Nakamura Hajime、Takada Kohichi、Hayasaka Naotaka、Kubo Tomohiro、Umeyama Yui、Iyama Satoshi、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Oncology Letters
  
  Volume: 22 Issue: 1 Pages: 546-546
- DOI
  10.3892/ol.2021.12807
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08397, KAKENHI-PROJECT-19K08871
[Journal Article] Potential drug?drug interactions in the era of integrase strand transfer inhibitors: a cross-sectional single-center study in Japan2021
- Author(s)
  Kunimoto Yusuke、Matamura Ryosuke、Ikeda Hiroshi、Fujii Satoshi、Kimyo Tomoko、Kitagawa Manabu、Nakata Hiromasa、Kobune Masayoshi、Miyamoto Atsushi、Fukudo Masahide
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 7 Issue: 1 Pages: 43-43
- DOI
  10.1186/s40780-021-00226-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08871, KAKENHI-PROJECT-20K07126
[Journal Article] Possible clinical outcomes using early enteral nutrition in individuals with allogeneic hematopoietic stem cell transplantation: A single-center retrospective study2021
- Author(s)
  Satoshi Iyama, Hiroomi Tatsumi, Tsukasa Shiraishi, Shohei Kikuchi, Tsutomu Sato, Hirofumi Ohnishi, Shin-Ichi Yokota, Masayoshi Kobune
- Journal Title
  
  Nutrition
  
  Volume: 83 Pages: 111093-111093
- DOI
  10.1016/j.nut.2020.111093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23921, KAKENHI-PROJECT-19K08871
[Journal Article] Combination of psoas muscle mass index and neutrophil/lymphocyte ratio as a prognostic predictor for patients undergoing <scp>nonsurgical</scp> hepatocellular carcinoma therapy2021
- Author(s)
  Sugama Yusuke、Miyanishi Koji、Osuga Takahiro、Tanaka Shingo、Hamaguchi Kota、Ito Ryo、Sakamoto Hiroki、Kubo Tomohiro、Ohnuma Hiroyuki、Murase Kazuyuki、Takada Kohich、Kobune Masayoshi、Kato Junji
- Journal Title
  
  JGH Open
  
  Volume: 5 Issue: 12 Pages: 1335-1343
- DOI
  10.1002/jgh3.12676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08871
[Journal Article] Diffuse large B cell lymphoma with HIV infection presented with disseminated thromboembolism during antiretroviral therapy2020
- Author(s)
  池田博、井山諭、加藤淳二、小船雅義、長島加奈、藤田千紗、後藤亜香利、堀口拓人、菊地尚平、村瀬和幸、高田弘一
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 61 Issue: 11 Pages: 1595-1599
- DOI
  10.11406/rinketsu.61.1595
- NAID
  130007951912
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08871
[Journal Article] 骨髄異形成症候群などの骨髄不全症候群における鉄過剰症の治療2020
- Author(s)
  小船雅義
- Journal Title
  
  臨床血液
  
  Volume: 61 Pages: 753-763
- NAID
  130007884767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08871
[Journal Article] Acquired amegakaryocytic thrombocytopenic purpura possibly induced by anti-PD-1 antibody2020
- Author(s)
  Iyama Satoshi、Takada K.、Yoshida M.、Takahashi D.、Kobune M.
- Journal Title
  
  Annals of Hematology
  
  Volume: 99 Issue: 7 Pages: 1669-1670
- DOI
  10.1007/s00277-020-04053-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08871
[Journal Article] Successful Treatment by Surgery and Lenvatinib of a Patient with Adrenal Metastasis of Papillary Thyroid Cancer2020
- Author(s)
  Nakamura Hajime、Takada Kohichi、Murase Kazuyuki、Sakamoto Hiroki、Hayasaka Naotaka、Ishikawa Kazuma、Ikeda Yuki、Yoshida Makoto、Iyama Satoshi、Kobayashi Ko、Shindo Tetsuya、Sugita Shintaro、Miyanishi Koji、Kobune Masayoshi、Masumori Naoya、Kato Junji
- Journal Title
  
  Case Reports in Oncological Medicine
  
  Volume: 2020 Pages: 1-4
- DOI
  10.1155/2020/2107430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08871
[Journal Article] EPO-R+ myelodysplastic cells with ring sideroblasts produce high erythroferrone levels to reduce hepcidin expression in hepatic cells2019
- Author(s)
  Miura, S. Kobune, M. Horiguchi, H. Kikuchi, S. Iyama, S. Murase, K. Goto, A. Ikeda, H. Takada, K. Miyanishi, K. Kato, J.
- Journal Title
  
  Blood Cells Mol Dis
  
  Volume: 78 Pages: 1-8
- DOI
  10.1016/j.bcmd.2019.04.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08871
[Journal Article] miR-7977 inhibits the Hippo-YAP signaling pathway in bone marrow mesenchymal stromal cells2019
- Author(s)
  Yoshida, M. Horiguchi, H. Kikuchi, S. Iyama, S. Ikeda, H. Goto, A. Kawano, Y. Murase, K. Takada, K. Miyanishi, K. Kato, J. Kobune, M.
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 3 Pages: e0213220-e0213220
- DOI
  10.1371/journal.pone.0213220
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08871
[Journal Article] Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma2017
- Author(s)
  Arihara Yohei、Takada Kohichi、Kamihara Yusuke、Hayasaka Naotaka、Nakamura Hajime、Murase Kazuyuki、Ikeda Hiroshi、Iyama Satoshi、Sato Tsutomu、Miyanishi Koji、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 39 Pages: 65889-65899
- DOI
  10.18632/oncotarget.19508
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599, KAKENHI-PROJECT-15K09482
[Journal Article] Effect of duloxetine in Japanese patients with chemotherapy-induced peripheral neuropathy: a pilot randomized trial.2015
- Author(s)
  Hirayama Y, Ishitani K, Sato Y, Iyama S, Takada K, Murase K, Kuroda H, Nagamachi Y, Konuma Y, Fujimi A, Sagawa T, Ono K, Horiguchi H, Terui T, Koike K, Kusakabe T, Sato T, Takimoto R, Kobune M, Kato J
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 20 Issue: 5 Pages: 866-871
- DOI
  10.1007/s10147-015-0810-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09482, KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461430
[Journal Article] Phase I trial of oral S-1 combined with hepatic arterial infusion of gemcitabine in unresectable biliary tract cancer.2015
- Author(s)
  Ishiwatari H, Hayashi T, Kato J, et al.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 75 Issue: 4 Pages: 805-812
- DOI
  10.1007/s00280-015-2704-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591027, KAKENHI-PROJECT-15K09482, KAKENHI-PROJECT-26461037
[Journal Article] Increased duodenal iron absorption through upregulation of DMT1 due to enhancement of IRP1 activity in patients with NASH.2015
- Author(s)
  Hoki T, Miyanishi K, Kato J, et al.
- Journal Title
  
  Hepatology
  
  Volume: 印刷中 Issue: 3 Pages: 751-761
- DOI
  10.1002/hep.27774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591027, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09013, KAKENHI-PROJECT-15K09482
[Journal Article] A novel strategy inducing autophagic cell death in Burkitt’s lymphoma cells with anti-CD19-targeted liposomal rapamycin.2014
- Author(s)
  Ono K, Sato T, Iyama S, Tatekoshi A, Hashimoto A, Kamihara Y, Horiguchi H, Kikuchi S, Kawano Y,Takada K, Hayashi T, Miyanishi K, Sato Y, Takimoto R, Kobune M, Kato J.
- Journal Title
  
  Blood Cancer J
  
  Volume: 7 Issue: 2 Pages: e180-e180
- DOI
  10.1038/bcj.2014.2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-24659372, KAKENHI-PROJECT-24659466
[Journal Article] Fucosylated TGF-ß receptors transduces a signal for epithelial-mesenchymal transition in colorectal cancer cells.2014
- Author(s)
  Hirakawa M, Takimoto R, Tamura F, Yoshida M, Ono M, Murase K, Sato Y, Osuga T, Sato T, Iyama S, Miyanishi K, Takada K, Hayashi T, Kobune M, Kato J.
- Journal Title
  
  Br J Cancer
  
  Volume: 110 Issue: 1 Pages: 156-163
- DOI
  10.1038/bjc.2013.699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-24659372
[Journal Article] RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells2014
- Author(s)
  Tamura F, Sato Y, Hirakawa M, Yoshida M, Ono M, Osuga T, Okagawa Y, Uemura N, Arihara Y, Murase K, Kawano Y, Iyama S, Takada K, Hayashi T, Sato T, Miyanishi K, Kobune M, Takimoto R, Kato J.
- Journal Title
  
  Gastric Cancer
  
  Volume: 23 Issue: 1 Pages: 85-97
- DOI
  10.1007/s10120-014-0454-z
- NAID
  40020700032
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590921, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09508
[Journal Article] Efficacy of Enteral Supplementation Enriched with Glutamine, Fiber, and Oligosaccharide on Mucosal Injury following Hematopoietic Stem Cell Transplantation2014
- Author(s)
  Iyama S, Sato T, Tatsumi H, Hashimoto A, Tatekoshi A, Kamihara Y, Horiguchi H, Ibata S, Ono K, Murase K, Takada K, Sato Y, Hayashi T, Miyanishi K, Akizuki E, Nobuoka T, Mizuguchi T, Takimoto R, Kobune M, Hirata K, Kato J.
- Journal Title
  
  Case Rep Oncol
  
  Volume: 7 Issue: 3 Pages: 692-699
- DOI
  10.1159/000368714
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591427, KAKENHI-PROJECT-25461430
[Journal Article] Narrowband ultraviolet B phototherapy ameliorates acute graft-versus-host disease by a mechanism involving in vivo expansion of CD4+CD25+Foxp3+ regulatory T cells．2014
- Author(s)
  Iyama S，Murase K，Sato T，Hashimoto A，Tatekoshi A，Horiguchi H，Kamihara Y，Ono K，Kikuchi S，Takada K，Kawano Y，Hayashi T，Miyanishi K，Sato Y，Takimoto R，Kobune M，Mori S，Kato J，Yamashita T，Kato J．
- Journal Title
  
  Int J Hematol
  
  Volume: 99 Issue: 4 Pages: 471-476
- DOI
  10.1007/s12185-014-1530-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591427, KAKENHI-PROJECT-24659466, KAKENHI-PROJECT-25461705
[Journal Article] A phase II study of neoadjuvant combination chemotherapy with docetaxel, cisplatin, and S-1 for locally advanced resectable gastric cancer: nucleotide excision repair (NER) as potential chemoresistance marker.2013
- Author(s)
  Hirakawa M, Sato Y, Takimoto R, Kobune M, Hirata K, Kato J, et al.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 71 Pages: 789-797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591403
[Journal Article] Increased hepatic oxidative DNA damage in patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma.2013
- Author(s)
  Tanaka S, Miyanishi K, Kobune M, Takimoto R, Kato J, et al.
- Journal Title
  
  J Gastroenterol.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591403
[Journal Article] Treatment of pancreatic fibrosis with siRNA against a collagen-specific chaperone in vitamin A-coupled liposomes.2013
- Author(s)
  Ishiwatari H, Sato Y, Murase K, Yoneda A, Fujita R, Nishita H, Birukawa NK, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Ota S, Kimura Y, Hirata K, Kato J, Niitsu Y.
- Journal Title
  
  Gut
  
  Volume: 62(9) Issue: 9 Pages: 1328-39
- DOI
  10.1136/gutjnl-2011-301746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-24659372, KAKENHI-PROJECT-24659592
[Journal Article] Improvement of iron-mediated oxidative DNA damage in patients with transfusion-dependent myelodysplastic syndrome by treatment with deferasirox.2012
- Author(s)
  Kikuchi S, Kobune M, Iyama S, Sato T, Murase K, Kawano Y, Takada K, Ono K, Kaneko Y, Miyanishi K, Sato Y, Hayashi T, Takimoto R, Kato J.
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 23(6) Issue: 4 Pages: 548-550
- DOI
  10.1016/j.freeradbiomed.2012.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24659466
[Journal Article] Successful treatment by fibrin glue sealant for pneumothorax with chronic GVHD resistant to autologous blood patch pleurodesis2012
- Author(s)
  Iyama S, Sato T, Murase K, Kikuchi S, Kamihara Y, Ono K, Takada K, Miyanishi K, Sato Y, Takimoto R, Kobune M, Obama T, Miyajima M, Watanabe A, Higami T, Hirayama Y, Kato J
- Journal Title
  
  Intern Med
  
  Volume: 51(15) Pages: 2011-4
- NAID
  130002062268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591043
[Journal Article] Prognostic significance of serum-ferritin level at diagnosis in myelodysplastic syndrome2012
- Author(s)
  Kobune M, et al. 2^<nd>
- Journal Title
  
  Int J Hematol
  
  Volume: (In press) Issue: 5 Pages: 527-534
- DOI
  10.1007/s12185-012-1048-3
- NAID
  10030633185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213, KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24659372, KAKENHI-PROJECT-24659466
[Journal Article] Intermittent administration of recombinant human soluble thrombomodulin successfully controlled chronic disseminated intravascular coagulation in a patient with dissecting aortic aneurysm on an outpatient basis2012
- Author(s)
  Iyama S, Sato T, Murase K, Kamihara Y, Ono K, Kikuchi S, Takada K, Miyanishi K, Sato Y, Takimoto R, Kobune M, Kato J
- Journal Title
  
  Blood Coagul Fibrinolysis
  
  Volume: 23(6) Pages: 548-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591043
[Journal Article] Prognostic significance of serum ferritin level at diagnosis in myelodysplastic syndrome2012
- Author(s)
  Kobune M
- Journal Title
  
  Int J Hematol
  
  Volume: 95 Pages: 527-534
- NAID
  10030633185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Establishment of a simple test for iron absorption from the gastrointestinal tract2011
- Author(s)
  Kobune M
- Journal Title
  
  Int J Hematol
  
  Volume: 93 Pages: 715-719
- NAID
  10029535427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Iron chelator deferasirox rescued mice from Fas-induced fulminant hepatitis2011
- Author(s)
  Sato T, Kobune M, Murase K, Kado Y, Okamoto T, Tanaka S, Kikuchi S, Nagashima H, Kawano Y, Takada K, Iyama S, Miyanishi K, Sato Y, Takimoto R, Kato J
- Journal Title
  
  Hepatol Res
  
  Volume: 41(7) Pages: 660-7
- NAID
  10031144136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591043
[Journal Article] Iron chelator deferasirox rescued mice from Fas-induced fulminant hepatitis2011
- Author(s)
  Sato T, Kobune M, Takimoto R, Kato J
- Journal Title
  
  Hepatol Res
  
  Volume: 41(7) Pages: 660-7
- NAID
  10031144136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231
[Journal Article] Novel missense mutation in the TMPRSS6 gene in a Japanese female with iron-refractory iron deficiency anemia2011
- Author(s)
  Sato T, Takimoto R, Kobune M, Kato J
- Journal Title
  
  Int J Hematol
  
  Volume: 94(1) Pages: 101-3
- NAID
  10029536603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231
[Journal Article] Argon plasma coagulation treatment of hemorrhagic radiation proctopathy : the optimal settings for application and long-term outcome2011
- Author(s)
  Sato Y, Takimoto R, Kobune M, Kato J
- Journal Title
  
  Gastrointest Endosc
  
  Volume: 73(3) Pages: 543-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231
[Journal Article] Establishment of a simple test for iron absorption from the gastrointestinal tract2011
- Author(s)
  Kobune M, Takimoto R, Kato, J
- Journal Title
  
  Int J Hematol
  
  Volume: 93 Issue: 6 Pages: 715-719
- DOI
  10.1007/s12185-011-0878-8
- NAID
  10029535427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231, KAKENHI-PROJECT-23890169
[Journal Article] Establishment of a simple test for iron absorption from the gastrointestinal tract2011
- Author(s)
  Kobune M, Takimoto R, Kato J
- Journal Title
  
  Int J Hematol
  
  Volume: 93(6) Pages: 715-9
- NAID
  10029535427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231
[Journal Article] Novel missense mutation in the TMPRSS6 gene in a Japanese female with iron-refractory iron deficiency anemia2011
- Author(s)
  Sato T, Iyama S, Murase K, Kamihara Y, Ono K, Kikuchi S, Takada K, Miyanishi K, Sato Y, Takimoto R, Kobune M, Kato J
- Journal Title
  
  J Hematol
  
  Volume: 94(1) Pages: 101-3
- NAID
  10029536603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591043
[Journal Article] A phase I trial of arterial infusion chemotherapy with gemcitabine and 5-fluorouracil for unresectable biliary tract cancer2011
- Author(s)
  Hayashi T, Kobune M, Takimoto R, Kato J
- Journal Title
  
  Int J Clin Oncol
- NAID
  10031144337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231
[Journal Article] Novel missense mutation in the TMPRSS6 gene in a Japanese female with iron-refractory iron deficiency anemia2011
- Author(s)
  Sato T, Takimoto R, Kato J
- Journal Title
  
  Int J Hematol
  
  Volume: 94 Issue: 1 Pages: 101-103
- DOI
  10.1007/s12185-011-0881-0
- NAID
  10029536603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231, KAKENHI-PROJECT-21591213, KAKENHI-PROJECT-22591043, KAKENHI-PROJECT-23890169
[Journal Article] Pure red cell aplasia associated with Good's syndrome accompanied by decreased stem cell factor production in the bone marrow2010
- Author(s)
  Kuribayashi K, Kobune M
- Journal Title
  
  Intern Med
  
  Volume: 49 Pages: 377-382
- NAID
  130000251680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Pure red cell aplasia associated with Good's syndrome accompanied by decreased stem cell factor production in the bone marrow.2010
- Author(s)
  Kuribayashi K, Kobune M, et al.
- Journal Title
  
  Intern Med.
  
  Volume: 49 Pages: 377-382
- NAID
  130000251680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Phase II study of S-1, docetaxel and cisplatin combination chemotherapy in patients with unresectable metastatic gastric cancer2010
- Author(s)
  Sato Y, Takimoto R, Kobune M, Niitsu Y, Kato J
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 66(4) Pages: 721-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231
[Journal Article] Endoscopic findings of enteropathy-type T-cell lymphoma by double-balloon enteroscopy and capsule endoscopy2010
- Author(s)
  Sato Y, Kobune M
- Journal Title
  
  Dig Endosc
  
  Volume: 22 Pages: 243-245
- NAID
  10028187103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Endoscopic findings of enteropathy-type T-cell lymphoma by double-balloon enteroscopy and capsule endoscopy.2010
- Author(s)
  Sato Y, Kobune M, et al.
- Journal Title
  
  Dig Endosc.
  
  Volume: 22 Pages: 243-245
- NAID
  10028187103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Phase II study of S-1, docetaxel and cisplatin combination chemotherapy in patients with unresectable metastatic gastric cancer. Cancer Chemother Pharmacol.2010
- Author(s)
  Sato Y, Kobune M, et al.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 66 Pages: 721-728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Late onset neutropenia and immunoglobulin suppression of the patientswith malignant lymphoma following autologous stem cell transplantation with rituximab2009
- Author(s)
  Hirayama Y, Kobune M
- Journal Title
  
  Intern Med
  
  Volume: 48 Pages: 57-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Drug resistance is dramatically restored by hedgehog inhibitors in CD34+leukemic cells2009
- Author(s)
  Kobune M, Takimoto R, Kato J
- Journal Title
  
  Cancer Sci
  
  Volume: 100(5) Pages: 948-55
- NAID
  10025145994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231
[Journal Article] Drug resistance is dramatically restored by hedgehog inhibitors in CD34+leukemic cells2009
- Author(s)
  Kobune M
- Journal Title
  
  Cancer Sci
  
  Volume: 100 Pages: 948-955
- NAID
  10025145994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells2009
- Author(s)
  Kobune M, Kato J, et al.
- Journal Title
  
  Cancer Sci. 100(5)
  
  Pages: 948-55
- NAID
  10025145994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231
[Journal Article]2009
- Author(s)
  小船雅義, 加藤淳二
- Journal Title
  
  血液疾患アプローチのための解剖生理. 病気と薬パーフェクトBOOK2009(南山堂)
  
  Pages: 1202-1205
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Late onset neutropenia and immunoglobulin suppression of the patients with malignant lymphoma following autologous stem cell transplantation with rituximab2009
- Author(s)
  Hirayama Y, Kohda K, Konuma Y, Hirata Y, Kuroda H, Fujimi Y, Shirao S, Kobune M, Takimoto R, Matsunaga T, Kato J
- Journal Title
  
  Intern Med 48
  
  Pages: 57-60
- NAID
  130000080003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] De novo follicular regeneration of the skin by wingless int 3 and bone morphogenetic protein 2 genes introduced into dermal fibroblasts and fibroblast growth factor-2 protein2009
- Author(s)
  Ono I, Kobune M, et al
- Journal Title
  
  Wound Rep Reg 17
  
  Pages: 436-446
- NAID
  10031181580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Suppressive effect of sulindac on branch duct-intraductal papillary mucinous neoplasms2009
- Author(s)
  Hayashi T, Kobune M, et al
- Journal Title
  
  J Gastroenterol 44
  
  Pages: 964-975
- NAID
  10025581446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] De novo follicular regeneration of the skin by wingless int 3 and bone morphogenetic protein 2 genes introduced into dermal fibroblasts and fibroblast growth factor-2 protein2009
- Author(s)
  Ono I, Kobune M
- Journal Title
  
  Wound Rep Reg
  
  Volume: 17 Pages: 436-446
- NAID
  10031181580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Late onset neutropenia and immunoglobulin suppression of the patients with malignant lymphoma following autologous stem cell transplantation with rituximab2009
- Author(s)
  Hirayama Y, Kobune M, et al
- Journal Title
  
  Intern Med 48
  
  Pages: 57-60
- NAID
  130000080003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells2009
- Author(s)
  Kobune M, et al
- Journal Title
  
  Cancer Sci 100
  
  Pages: 948-955
- NAID
  10025145994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591213
[Journal Article] Suppressive effect of sulindac on branch duct-intraductal papillary mucinous neoplasms2009
- Author(s)
  Hayashi T, Kobune M, Takimoto R, Kato J, Niitsu Y
- Journal Title
  
  J Gastroenterol
  
  Volume: 44(9) Pages: 964-75
- NAID
  10025581446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390231
[Journal Article] Adenoviral vector-mediated transfer of the indian hedgehog gene modulates lymphomyelopoiesis in vivo2008
- Author(s)
  Kobune-M, et al.
- Journal Title
  
  Stem Cells 26
  
  Pages: 534-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Resolution of liver ci rrhosis using vitamin A-coupled lip osomes to deliver siRNA against a collagen-specific chaperone2008
- Author(s)
  Sato Y, Kato J, Kobune M, Miya nishi K, et.al.
- Journal Title
  
  Nature biotechnology 26(4)
  
  Pages: 431-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390202
[Journal Article] Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone2008
- Author(s)
  Sato Y, Murase K, Kato J, Kobune M, Sato T, Kawano Y, Takimoto R, Takada K, Miyanishi K, Matsunaga T, Takayama T, Niitsu Y
- Journal Title
  
  Nat Biotechnol 26
  
  Pages: 431-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Resolution of liver cirrhosis using vitamine A-coupled liposomes to deliver siRNA against a collagen-specific chaperone2008
- Author(s)
  Kobune-M, et al. (12中4番目)
- Journal Title
  
  Nat Biotechnol 26
  
  Pages: 431-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Successful treatment of autoimmune pancreatitis complicated with autoimmune thrombocytopenia and interstitial pneumonia by prednisolone2008
- Author(s)
  Murase K, Matsunaga T, Hayashi T, Ishiwatari H, Araki N, Iyama S, Sato T, Kobune M, Takimoto R, Miyanishi K, Miyazaki T, Ikeda H, Kato J, Niitsu Y
- Journal Title
  
  Intern Med 47
  
  Pages: 1033-1038
- NAID
  130000078663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin-CD34-cells2008
- Author(s)
  Kobune M, Kawano Y, Takahashi S, Takada K, Murase K, Iyama S, Sato T, Takimoto R, Niitsu Y, Kato J
- Journal Title
  
  Exp Hematol 36
  
  Pages: 1121-1131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Apoptosis supercedes necrosis in mitochondrial DNA-depleted Jurkat cells by cleavage of receptorinteracting protein and inhibition of lysosomal cathepsin2008
- Author(s)
  Sato T, Machida T, Takahashi S, Murase K, Kawano Y, Hayashi T, Iyama S, Takada K, Kuribayashi K, Sato Y, Kobune M, Takimoto R, Matsunaga T, Kato J, Niitsu Y
- Journal Title
  
  J Immunol 181
  
  Pages: 197-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Ex vivo large-scale generation of human red blood cells from cord blood CD34(+)cells by co-culturing with macrophages2008
- Author(s)
  Fujimi A, Matsunaga T, Kobune M, Kawano Y, Nagaya T, Tanaka I, Iyama S, Hayashi T, Sato T, Miyanishi K, Sagawa T, Sato Y, Takimoto R, Takayama T, Kato J, Gasa S, Sakai H, Tsuchida E, Ikebuchi K, Hamada H, Niitsu Y
- Journal Title
  
  Int J Hematol 87
  
  Pages: 339-350
- NAID
  10025158459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin-CD34- cells2008
- Author(s)
  Kobune-M, et al.
- Journal Title
  
  Exp Hematol 36
  
  Pages: 1121-1131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Treatment of hepatocellular carcinoma by AdAFPep/rep, AdAFPep/p53, and 5-fluorouracil in mice2008
- Author(s)
  Sagawa T, Kato J, Kobune M, Miyanishi K, et.al.
- Journal Title
  
  Hepatology 48(3)
  
  Pages: 828-840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390202
[Journal Article] Adenoviral vector-mediated transfer of the indian hedgehog gene modulates lymphomyelopoiesis in vivo2008
- Author(s)
  Kobune M, Kato J, Kawano Y, Sasaki K, Uchida H, Takada K, Takahashi S, Takimoto R, Niitsu Y
- Journal Title
  
  Stem Cells 26
  
  Pages: 534-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Apoptosis supercedes necrosis in mitochondrial DNA-depleted Jurkat cells by cleavage of receptor-interacting protein and inhibition of lysosomal cathepsin2008
- Author(s)
  Kobune-M, et al. (11中14番目)
- Journal Title
  
  J Immunol 181
  
  Pages: 197-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Successful treatment of chronic myeloproliferative diseaseunclassifiable(CMPD-U)with no chromosomal abnormalities by imatinib mesylate2008
- Author(s)
  Iyama S, Matsunaga T, Sato T, Murase K, Araki N, Takimoto R, Kobune M, Sagawa T, Takayama T, Niitsu Y
- Journal Title
  
  Intern Med 47
  
  Pages: 791-794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation2007
- Author(s)
  Junji Kato, Masayoshi Kobune
- Journal Title
  
  Experimental hematology (in press)
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Long-term phlebotomy with low-iron diet therapy lower risk of development of hepatocellular carcinoma from chronic hepatitis C2007
- Author(s)
  Kato J, Miyanishi K, Kobune M et.al.
- Journal Title
  
  J Gastroenterology 42
  
  Pages: 830-836
- NAID
  40019559860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390202
[Journal Article] Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation2007
- Author(s)
  Kato J, Kobune M, et al.
- Journal Title
  
  Exp Hematol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390220
[Journal Article] Adenoviral Vector-Mediated Transfer of the Indian Hedgehog Gene Modulates Lymphomyelopoiesis in vivo.2007
- Author(s)
  Kobune M, et. al.
- Journal Title
  
  Stem Cells 26
  
  Pages: 534-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation.2007
- Author(s)
  Kato J, Kobune M, et al.
- Journal Title
  
  Exp Hematol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390220
[Journal Article] Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation2007
- Author(s)
  Kato J, Kobune M, Ohkubo S, Fujikawa K, Tanaka M, Takimoto R, Takada K, Takahari D, Kawano Y, Kohgo Y, Niitsu Y
- Journal Title
  
  Exp Hematol 35
  
  Pages: 879-887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Wnt3/RhoA/ROCK signaling pathway is involved in adhesion-mediated drug resistance of multiple myeloma in an autocrine mechanism2007
- Author(s)
  Kobune M, Chiba H, Kato J, Kato K, Nakamura K, Kawano Y, Takada K, Takimoto R, Takayama T, Hamada H, Niitsu-Y
- Journal Title
  
  Mol Cancer Ther 6
  
  Pages: 1774-1784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Effective genetic modification of mesenchymal stem cells.2007
- Author(s)
  Kobune-M, Niitsu-Y, et al.
- Journal Title
  
  Genome medicine, Medical review inc
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Wnt3/RhoA/ROCK signaling pathway is involved in adhesion-mediated drug resistance of multiple myeloma in an autocrine mechanism.2007
- Author(s)
  Kobune M, et. al.
- Journal Title
  
  Molecular Cancer Therapeutics 6
  
  Pages: 1774-1784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591124
[Journal Article] Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation.2007
- Author(s)
  Kato-J, Kobune-M, et al.
- Journal Title
  
  Experimental hematology
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation2007
- Author(s)
  Kato-J, Kobune-M
- Journal Title
  
  Experimental hematology (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Ex Vivo Large Scale Generation of Human Platelets From Cord Blood CD34+ Cells.2006
- Author(s)
  Matsunaga-T, Kobune-M, et al.
- Journal Title
  
  Stem cells 24 (12)
  
  Pages: 2877-2887
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Ex vivo expansion of G-CSF-mobilized peripheral blood CD133+ progenitor cells on coculture with human stromal cells2006
- Author(s)
  Kawano-Y, Kobune-M
- Journal Title
  
  Experimental hematology 34(2)
  
  Pages: 150-158
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Ex vivo expansion of G-CSF-mobilized peripheral blood CD133+ progenitor cells on coculture with human stromal cells2006
- Author(s)
  Yutaka Kawano, Masayoshi Kobune
- Journal Title
  
  Experimental hematology 34(2)
  
  Pages: 150-158
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Ex vivo expansion of G-CSF-mobilized peripheral blood CD133+ progenitor cells on coculture with human stromal cells.2006
- Author(s)
  Kawano-Y, Kobune-M, et al.
- Journal Title
  
  Experimental hematology 34 (2)
  
  Pages: 150-158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Ex Vivo Large Scale Generation of Human Platelets From Cord Blood CD34+ Cells2006
- Author(s)
  Matsunaga-T, Kobune-M
- Journal Title
  
  Stem Cells 24(12)
  
  Pages: 2877-2887
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Ex Vivo Large Scale Generation of Human Platelets From Cord Blood CD34+ Cells2006
- Author(s)
  Takuya Matsunaga, Masayoshi Kobune
- Journal Title
  
  Stem Cells 24(12)
  
  Pages: 2877-2887
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Mesenchymal stem cells (MSC) as therapeutic cytoreagents for gene therapy2005
- Author(s)
  Hirofumi Hamada, Masayoshi Kobune
- Journal Title
  
  Cancer Sci 96(3)
  
  Pages: 149-156
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Expansion of CD34+ cells on telomerized human stromal cells without losing erythroid-differentiation potential in a serum-free condition.2005
- Author(s)
  Kobune M, Kato J, et al.
- Journal Title
  
  Int J Hematol. 81・1
  
  Pages: 18-25
- NAID
  10014282469
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390220
[Journal Article] Mesenchymal Stem Cells That Produce Neurotrophic Factors Reduce Ischemic Damage in the Rat Middle Cerebral Artery Occlusion Model2005
- Author(s)
  Kazuhiko Kurozumi, Masayoshi Kobune
- Journal Title
  
  Molecular therapy 11(1)
  
  Pages: 96-104
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Telomerized human bone marrow-derived cell clones maintain the phenotype of hematopoietic-supporting osteoblastic and myofibroblastic stromal cells after long-term culture.2005
- Author(s)
  Kobune M, Kato J, et al.
- Journal Title
  
  Exp Hematol. 33・12
  
  Pages: 1544-1553
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390220
[Journal Article] Telomerized human bone marrow-derived cell clones maintain the phenotype of hematopoietic-supporting osteoblastic and myofibroblastic stromal cells after long-term culture.2005
- Author(s)
  Kobune M, Kato J, et al.
- Journal Title
  
  Exp Hematol 33・12
  
  Pages: 1544-1553
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390220
[Journal Article] Expansion of CD34+ cells on telomerized human stromal cells without losing erythroid differentiation potential in a serum-free condition2005
- Author(s)
  Masayoshi Kobune
- Journal Title
  
  Int J Hematology 81(1)
  
  Pages: 18-25
- NAID
  10014282469
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Human mesenchymal stem cells xenografted directly to rat liver differentiated into human hepatocytes without fusion.2005
- Author(s)
  Yasushi Sato, Masayoshi Kobune
- Journal Title
  
  Blood 106(2)
  
  Pages: 756-763
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Expansion of CD34+ cells on telomerized human stromal cells without losing erythroid-differentiation potential in a serum-free condition2005
- Author(s)
  Masayoshi Kobune
- Journal Title
  
  Int.J Hematol. 81,No 1
  
  Pages: 18-25
- NAID
  10014282469
- Data Source
  KAKENHI-PROJECT-15790496
[Journal Article] Telomerized human bone marrow derived cell clones maintain the phenotype of hematopoietic-supporting osteoblastic and myofibroblastic stromal cells after long-term culture.2005
- Author(s)
  Masayoshi Kobune
- Journal Title
  
  Experimental hematology 33(12)
  
  Pages: 1543-1552
- Data Source
  KAKENHI-PROJECT-17591003
[Journal Article] Telomerized human bone marrow-derived cell clones maintain the phenotype of hematopoietic-supporting osteoblastic and myofibroblastic stromal cells after long-term culture.2005
- Author(s)
  Kobune M, Kato J, et al.
- Journal Title
  
  Exp Hematol 33・12
  
  Pages: 1544-1553
- Data Source
  KAKENHI-PROJECT-17013074
[Journal Article] Wnt3 modulates the characteristics and cobblestone area-supporting activity of human stromal cells2004
- Author(s)
  Hiroki Chiba, Masayoshi Kobune
- Journal Title
  
  Experimental hematology 32,No 12
  
  Pages: 1194-1203
- Data Source
  KAKENHI-PROJECT-15790496
[Journal Article] Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-β2m-/- repopulating cells2004
- Author(s)
  Masayoshi Kobune
- Journal Title
  
  Blood Vol 104,No 4
  
  Pages: 1002-1009
- Data Source
  KAKENHI-PROJECT-15790496
[Journal Article] Indian Hedgehog Gene Transfer Augments Hematopoietic Support of Human Stromal cells Including NOD/SCID-Repopulating Cells2003
- Author(s)
  Masayoshi Kobune
- Journal Title
  
  Blood VOL 102 No.11
- Data Source
  KAKENHI-PROJECT-15790496
[Patent] インディアンヘッジホッグ遺伝子によるヒト骨髄ストローマ細胞の造血支持能の増強法2003
- Inventor(s)
  小船雅義
- Industrial Property Rights Holder
  レノメディクス研究所
- Filing Date
  2003-10-31
- Data Source
  KAKENHI-PROJECT-15790496
[Presentation] シンポジウム2「鉄剤の適正使用による貧血治療指針」:鉄欠乏・鉄欠乏性貧血の疫学・症状2023
- Author(s)
  小船雅義、堀口拓人、後藤亜香利、宮西浩嗣
- Organizer
  第47回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08509
[Presentation] EL3-4-3：高齢化社会における栄養障害による貧血の診断と治療2023
- Author(s)
  小船雅義
- Organizer
  第85回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08509
[Presentation] CD34+ Positive Myelodysplastic Cells with Ring Sideroblasts or SF3B1 Mutation Produce High Erythroferrone and GDF152020
- Author(s)
  Horiguchi　H, Kobune　M, Ono　K, Shimoyama　S, Fujita　C, Goto　A,　Ikeda　H, and Iyama S.
- Organizer
  American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08871
[Presentation] シンポジウム18「がん診療と輸血医療」:総論　がん診療と貧血．2020
- Author(s)
  小船雅義，堀口拓人.
- Organizer
  第68回日本輸血・細胞治療学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08871
[Presentation] シンポジウム4「輸血医療と鉄代謝」: 輸血後鉄過剰症が引き起こす細胞・臓器障害.2020
- Author(s)
  堀口拓人，小船雅義.
- Organizer
  第68回日本輸血・細胞治療学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08871
[Presentation] Treatment of iron overload in myelodysplastic syndromes and other bone marrow failure diseases.2019
- Author(s)
  小船雅義
- Organizer
  第81回日本血液学会学術集会.
- Data Source
  KAKENHI-PROJECT-19K08871
[Presentation] PCBP1発現低下による骨髄間質細胞の機能不全発症機序の解析2017
- Author(s)
  小船雅義、堀口拓人、宮西浩嗣、加藤淳二
- Organizer
  日本鉄バイオサイエンス学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09482
[Presentation] Extracellular vesicle microRNAs from acute myeloid leukemia are involved in the regulation of adherence junction in bone marrow microenvironment.2016
- Author(s)
  Masahiro Yoshida, Masayoshi Kobune, et al.
- Organizer
  American Society of Hematology
- Place of Presentation
  サンディエゴ
- Year and Date
  2016-12-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09482
[Presentation] Exosomal microRNAs in bone marrow cavity induce stromal dysfunction in AML/MDS2015
- Author(s)
  Hiroto Horiguchi, Masayoshi Kobune, Shohei Kikuchi, Kazuyuki Murase, Satoshi Iyama, Kohichi Takada, Tsutomu Sato, Yasushi Sato1), Koji Miyanishi1), Rishu Takimoto, Hiroyuki Kuroda, Masahiro Maeda, Junji Kato
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県金沢市ホテル日航金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K09482
[Presentation] 骨髄異形成症候群を増悪させる環境因子の解析2014
- Author(s)
  小船雅義，堀口拓人，定免渉，菊地尚平，村瀬和幸，井山　諭，高田弘一，
- Organizer
  第56回日本血液科学会秋季北海道地方会シンポジウム
- Place of Presentation
  北海道大学（北海道, 札幌市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24659466
[Presentation] Targeting Pancreatic Cancer Stem Like Cells Using a Nanoparticle Modified by L-Fucose．2013
- Author(s)
  Takimoto R，Yoshida M，Murase K，Sato Y，Hirakawa M，Tamura F，Sato T，Osuga T，Miyanishi K，Takada K，Hayash T，Kobune M，Kato J
- Organizer
  The American Association for the Study of Liver Diseases－Digestive Disease Week
- Place of Presentation
  Orlando, U.S.A.
- Invited
- Data Source
  KAKENHI-PROJECT-24591403
[Presentation] Long-Term ex vivo Production of Mature Erthroblasts from Umbilical Cord Blood Using a Coculture Systeme with Telomerized Human Stromal Cells2010
- Author(s)
  Kobune M, et al.
- Organizer
  JSH International Symposium 2010
- Place of Presentation
  Akita, Japan.
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21591213
[Presentation] Long-Term Production System of Red Blood Cells Using Human Cord Blood and Stromal Cells2010
- Author(s)
  Kobune M, et al.
- Organizer
  52nd American society of Hematology Annual Meeting 2010
- Place of Presentation
  Orlando, U.S.A.
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-21591213
[Presentation] Expression of DNA Repair Factor DDB2 Predicts Chemoresistance in Various Cancer Cell Lines2010
- Author(s)
  Miyanishi K, Kobune M, et al
- Organizer
  AACR 101st Annual Meeting 2010
- Place of Presentation
  Washington DC, U.S.A.
- Year and Date
  2010-04-18
- Data Source
  KAKENHI-PROJECT-21591213
[Presentation] Long-Term Production System of Red Blood Cells Using Human Cord Blood and Stromal Cells2010
- Author(s)
  Kobune M
- Organizer
  52nd American society of Hematology Annual Meeting
- Place of Presentation
  Orlando, U. S. A.
- Data Source
  KAKENHI-PROJECT-21591213
[Presentation] SMO阻害剤は急性骨髄性白血病細胞の薬剤耐性を解除する2010
- Author(s)
  小船雅義, 村瀬和幸, 井山諭, 佐藤勉, 瀧本理修, 菊地尚平, 宮西浩嗣, 佐藤康史, 加藤淳二
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591213
[Presentation] 鉄過剰症と鉄キレート療法の最新2010
- Author(s)
  小船雅義
- Organizer
  第58回日本輸血・細胞治療学会総会
- Place of Presentation
  名古屋(招待講演)
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-21591213
[Presentation] Long-Term ex vivo Production of Mature Erthroblasts from Umbilical Cord Blood Using a Coculture Systeme with Telomerized Human Stromal Cells2010
- Author(s)
  Kobune M
- Organizer
  JSH International Symposium
- Place of Presentation
  Akita, Japan
- Data Source
  KAKENHI-PROJECT-21591213
[Presentation] SMO阻害剤は急性骨髄性白血病細胞の薬剤耐性を解除する(ワークショップ)2010
- Author(s)
  小船雅義
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-06
- Data Source
  KAKENHI-PROJECT-21591213
[Presentation] Cyclopamine induced apoptosis in primary CD34+ acute leukemic cells2009
- Author(s)
  Kobune M, et al
- Organizer
  American Society of Hematology
- Place of Presentation
  New Orleans, USA
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-21591213
[Presentation] Cyclopamine induced apoptosis in primary CD34+acute leukemic cells2009
- Author(s)
  Kobune M
- Organizer
  American Society of Hematology
- Place of Presentation
  New Orleans, USA.
- Data Source
  KAKENHI-PROJECT-21591213
[Presentation] Hedgehog inhibitors reduce the survival and drug resistance in CD34+ leukemic cells2008
- Author(s)
  Kobune-M, et al.
- Organizer
  The 50th Annual Meet ing of American Society of Hematology
- Place of Presentation
  San Francisco, U. S. A
- Data Source
  KAKENHI-PROJECT-19591124
[Presentation] Wnt3 signaling augments integrinβ1-dependent adhesion-mediated drug resistance of multiple myeloma in autocrine and paracrine manner2008
- Author(s)
  Kobune M, Murase K, Iyama S, Sato T, Takimoto R, Kawano Y, Kikuchi S, Takada K, Miyanishi K, Sato Y, Kato J
- Organizer
  In : The 50th Annual Meeting of American Society of Hematology(Blood 2008 ; 112 : 1698a)
- Place of Presentation
  San Francisco, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591124
[Presentation] Hedgehog inhibitors reduce the survival and drug resistance in CD34+ leukemic cells2008
- Author(s)
  Kobune M, Murase K, Iyama S, Sato T, Takimoto R, Kikuchi S, Kawano Y, Takada K, Miyanishi K, Kato J
- Organizer
  In : The 50th Annual Meeting of American Society of Hematology(Blood 2008 ; 112 : 1611a)
- Place of Presentation
  San Francisco, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591124
[Presentation] Wnt3 signaling augments integrinβ1-dependent adhesion-mediated drug resistance of multiple myeloma in autocrine and paracrine manner2008
- Author(s)
  Kobune-M, et al.
- Organizer
  The 50th Annual Meeting of American Society of Hematology
- Place of Presentation
  San Francisco, U. S. A
- Data Source
  KAKENHI-PROJECT-19591124
[Presentation] Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin-CD34-cells via Wnt signaling2008
- Author(s)
  Kobune-M, et al.
- Organizer
  The 50th Annual Meeting of American Society of Hematology
- Place of Presentation
  San Francisco, U. S. A
- Data Source
  KAKENHI-PROJECT-19591124
[Presentation] Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin-CD34-cells via Wnt signaling2008
- Author(s)
  Kobune M, Murase K, Iyama S, Sato T, Kikuchi S, Kawano Y, Takada K, Miyanishi K, Takimoto R, Kato J
- Organizer
  In : The 50th Annual Meeting of American Society of Hematology(Blood 2008 ; 112 : 2325a)
- Place of Presentation
  San Francisco, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591124
[Presentation] Wnt3/RhoA/ROCK signaling pathway is involved in VLA6-dependent adhesion-mediated drug resistance of multiple myeloma.2007
- Author(s)
  Kobune M, et. al.
- Organizer
  The 49th Annual Meeting of American Society of Hematology : 2007
- Place of Presentation
  Atranta, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591124
[Presentation] Exosomes derived from AML/MDS cells could be involved in stromal dysfunction and bone marrow failure
- Author(s)
  Jomen W, Horiguchi H, Kobune M, Kikuchi S, Murase K, Ibata S, Iyama S, Sato T, Kamihara Y, Miyanishi K, Sato Y, Hayashi T, Takimoto R, Kato J
- Organizer
  2015 Highlights of ASH in Asia
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2015-02-28 – 2015-03-01
- Data Source
  KAKENHI-PROJECT-24659466
[Presentation] Exosomes Derived from AML/MDS Cells Is Involved in Stromal Dysfunction and Bone Marrow Failure.
- Author(s)
  Horiguchi H, Kobune M, Kikuchi S, Jomen W, Murase K, Ibata S, Iyama S, Sato T, Kamihara Y, Miyanishi K, Sato Y, Hayashi T, Takimoto R, Kato J.
- Organizer
  56th ASH Annual Meeting and Exposition
- Place of Presentation
  San Francisco, U.S.A
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24591427
[Presentation] Exosomes derived from AML/MDS cells could be involved in stromal dysfunction and bone marrow failure.
- Author(s)
  Horiguchi H, Kobune M, Kikuchi S, Jomen W, Murase K, Ibata S, Iyama S, Sato T, Kamihara Y, Miyanishi K, Sato Y, Hayashi T, Takimoto R, Kato J.
- Organizer
  56th ASH Annual Meeting and Exposition
- Place of Presentation
  San Francisco, U.S.A
- Year and Date
  2014-12-06 – 2014-12-11
- Data Source
  KAKENHI-PROJECT-24659466
[Presentation] Iron chelation therapy improves oxidative DNA damage in hematopoietic cells derived from transfusion-dependent myelodysplastic syndrome
- Author(s)
  Masayoshi Kobune
- Organizer
  International BioIron Society
- Place of Presentation
  ロンドン
- Data Source
  KAKENHI-PROJECT-24659466

1. KATO Junji (20244345)

# of Collaborated Projects: 12 results

# of Collaborated Products: 59 results
2. IYAMA Satoshi (50398319)

# of Collaborated Projects: 7 results

# of Collaborated Products: 13 results
3. SATO Tsutomu (40404602)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. MIYANISHI Koji (60372819)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
5. TAKIMOTO Rishu (10336399)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
6. KIKUCHI Shohei (80515792)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
7. Takada Kohichi (90398321)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
8. 堀口拓人 (70634674)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
9. 後藤亜香利 (60722387)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
10. KAMIHARA Yusuke (10624421)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. Murase Kazuyuki (90444918)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. 池田博 (60570132)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
13. KAWANO Yutaka (80398320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. HAYASHI Tsuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. ISHIWATARI Hirotoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 村松丈児

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 在原洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 中村元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 佐藤康史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 平川昌宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobune Masayoshi 小船 雅義

KOBUNE Masayoshi 小船 雅義

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Development of new therapy for AML by targeting of neuropeptide-PTH2R systemPrincipal Investigator

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Analysis of the development and pathogenesis of AML/MDS via extracellular vesiclesPrincipal Investigator

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The effect of exosomal miRNA on AML/MDS stromal cellsPrincipal Investigator

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Establishment of iron chelation therapy to inhibit the development of MDSPrincipal Investigator

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Development of dual targeting therapy for cancer stem cells and nichePrincipal Investigator

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Kobune Masayoshi 小船雅義

KOBUNE Masayoshi 小船雅義

[Book] 血液疾患．鉄欠乏性貧血　今日の治療指針　2023年版2023

[Book] 血液疾患．鉄欠乏性貧血Iron Deficiency Anemia (IDA)．今日の治療指針　2023年版2023