Ohno Shin-ichiro 大野慎一郎

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OHNO Shinichiro 大野慎一郎

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Researcher Number	90513680
Other IDs	https://orcid.org/0000-0003-1064-4750
Affiliation (Current)	2024: 東京医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京医科大学, 医学部, 講師 2011 – 2015: 東京医科大学, 医学部, 助教 2010: Tokyo University of Science, 研究員 2009: Tokyo University of Science, 生命科学研究所, ポストドクトラル研究員
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Experimental pathology / Human pathology / 膠原病・アレルギー・感染症内科学 Except Principal Investigator Basic Section 49020:Human pathology-related / Basic Section 56040:Obstetrics and gynecology-related / Experimental pathology / General surgery
Keywords	Principal Investigator microRNA / miRNA / 核酸医薬 / mouse model / DICER1 / RNA activation / TNRC6 / AGO / CDK9 / DDX21 … More / ノンコーディングRNA / ヘアピンRNA / RNA干渉 / Non-coding RNA / RNA interference / 炎症性サイトカイン / 肺がん / miR-34a / 慢性Ｃ型肝炎 / エクソソーム / HCV / ドラッグデリバリー / 免疫学 / アレルギー・ぜんそく … More Except Principal Investigator miRNA / non-coding RNA / microRNA / DICER1 / miRNA-122 / miRNA-5p / lncRNA / Dicer1症候群 / miR-122 / miR-5p / 肝間葉性過誤腫 / 胆管癌 / DICER1症候群 / 肝腫瘍 / Docer1症候群 / ESR1 / 子宮頸癌予防 / 子宮頸癌 / MACROD1 / CIN / WAPL / 分化誘導 / 不安定プラーク / Calponin / h-Caldesmon / 免染組織化学 / sirolimus / FAP / calponin / h-caldesmon / 免疫組織化学 / 平滑筋 / 冠動脈ステント / 動脈硬化 / 核酸医薬 / 肺がん / 核酸医薬品 / egh RNA / siRNA / 肺癌 / eghRNA / non-codingRNA / 癌 / がん / エキソソーム / 乳がん Less

Development of DICER1 syndrome model micePrincipal Investigator
- Principal Investigator
  
  大野慎一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokyo Medical University
Analysis of the mechanism of ncRNA-mediated carcinogenesis using the DICER1 syndrome model
- Principal Investigator
  
  黒田雅彦
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Tokyo Medical University
RNA activationにおける分子機構の解析Principal Investigator
- Principal Investigator
  
  大野慎一郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokyo Medical University
Does smooth muscle maturation, an indicator of plaque stabilization, also appear in the intima after drug-eluting stent placement?
- Principal Investigator
  
  Kurata Atsushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Tokyo Women's Medical University
  Tokyo Medical University
子宮頸癌の新規予防法開発
- Principal Investigator
  
  熊谷勝義
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokyo Medical University
Exploration and functional analysis of novel RNA-interfering nucleic acids.Principal Investigator
- Principal Investigator
  
  Ohno Shin-ichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokyo Medical University
Identification of novel non-coding RNA
- Principal Investigator
  
  Kuroda Masahiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical University
Development of novel form of mimic microRNA for microRNA replacement therapy.Principal Investigator
- Principal Investigator
  
  OHNO Shinichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical University
Development of novel nucleic acid drugs for chronic hepatitis C virus infectionPrincipal Investigator
- Principal Investigator
  
  OHNO Shinichiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical University
Development of a new miRNA delivery system for targeting cancer stem cells
- Principal Investigator
  
  UEDA Shinobu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Tokyo Medical University
アレルギー体質関連遺伝子の同定Principal Investigator
- Principal Investigator
  
  大野慎一郎
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Tokyo University of Science

[Book] 新たなドラッグデリバリーシステムとしてのエクソソーム.細胞工学2013
- Author(s)
  大野慎一郎、髙梨正勝、黒田雅彦
- Publisher
  秀潤社, vol.32 No.1
- Data Source
  KAKENHI-PROJECT-23659626
[Journal Article] MiR-34a induces myofibroblast differentiation from renal fibroblasts.2023
- Author(s)
  Suguru Saito, Shin-ichiro Ohno, Yuichirou Harada, Yoshihiko Kanno & Masahiko Kuroda.
- Journal Title
  
  Clinical and Experimental Nephrology (Clin Exp Nephrol)
  
  Volume: 27 Issue: 5 Pages: 411-418
- DOI
  10.1007/s10157-023-02329-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02706
[Journal Article] Prevalence of Merkel Cell Polyomavirus in Primary Eyelid Merkel Cell Carcinomas and Association With Clinicopathological Features.2023
- Author(s)
  Komatsu H, Usui Y, Sukeda A, Yamamoto Y, Ohno SI, Goto K, Kuroda M, Nagao T, Goto H.
- Journal Title
  
  American Journal of Ophthalmology
  
  Volume: 249 Pages: 49-56
- DOI
  10.1016/j.ajo.2022.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15432, KAKENHI-PROJECT-21H02706, KAKENHI-PROJECT-20K07417
[Journal Article] The prevalence of Merkel cell polyomavirus in primary eyelid Merkel cell carcinomas and association with clinical and histopathological characteristics.2022
- Author(s)
  小松紘之, 臼井嘉彦, 後藤浩, 助田葵, 山本善也, 長尾俊孝, 大野慎一郎, 黒田雅彦.
- Journal Title
  
  東京医科大学雑誌
  
  Volume: 80 Pages: 139-139
- Data Source
  KAKENHI-PROJECT-21H02706
[Journal Article] Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex2022
- Author(s)
  Shin-Ichiro Ohno, Keiki Oikawa, Toshiaki Tsurui, Yuichirou Harada, Kana Ono, Mizumo Tateishi, Aashiq Mirza, Masakatsu Takanashi, Kosuke Kanekura, Kumiko Nagase, Yoshihisa Shimada, Yujin Kudo, Norihiko Ikeda, Takahiro Ochiya, Xiaozhong Wang , Masahiko Kuroda
- Journal Title
  
  Cell Reports
  
  Volume: 12;39(2) Issue: 2 Pages: 110673-110673
- DOI
  10.1016/j.celrep.2022.110673
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06953, KAKENHI-PROJECT-20H03593, KAKENHI-PROJECT-21H02706
[Journal Article] A case report on death from acute bacterial cholangitis accompanied by von Meyenburg complexes2021
- Author(s)
  Watanabe Noriko、Ohno Shin-ichiro、Sakuma Moe、Kuriwaki Mayo、Miura Mai、Kuroda Masahiko
- Journal Title
  
  Medicine
  
  Volume: 100 Issue: 15 Pages: e25526-e25526
- DOI
  10.1097/md.0000000000025526
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02706, KAKENHI-PROJECT-20K16869
[Journal Article] Cisplatin inducesdifferentiation in teratomas derived from pluripotent stem cells.2021
- Author(s)
  Kurata A, Takanashi M, Ohno SI, Fujita K, Kuroda M.
- Journal Title
  
  Regen Ther.
  
  Volume: 18 Pages: 117-126
- DOI
  10.1016/j.reth.2021.05.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08382, KAKENHI-PROJECT-21H02706, KAKENHI-PROJECT-20K07398
[Journal Article] Prediction of non-muscle invasive bladder cancer recurrence using machine learning of quantitative nuclear features2021
- Author(s)
  Tokuyama Naoto、Saito Akira、Muraoka Ryu、Matsubara Shuya、Hashimoto Takeshi、Satake Naoya、Matsubayashi Jun、Nagao Toshitaka、Mirza Aashiq H.、Graf Hans-Peter、Cosatto Eric、Wu Chin-Lee、Kuroda Masahiko、Ohno Yoshio
- Journal Title
  
  Modern Pathology
  
  Volume: 35 Issue: 4 Pages: 533-538
- DOI
  10.1038/s41379-021-00955-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02706, KAKENHI-PROJECT-20K07417
[Journal Article] Acerola exosome-like nanovesicles to systemically deliver nucleic acid medicine via oral administration.2021
- Author(s)
  Umezu T, Takanashi M, Murakami Y, Ohno SI, Kanekura K, Sudo K, Nagamine K, Takeuchi S, Ochiya T, Kuroda M.
- Journal Title
  
  Molecular therapy. Methods & clinical development.
  
  Volume: 10;21 Pages: 199-208
- DOI
  10.1016/j.omtm.2021.03.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08382, KAKENHI-PROJECT-20H03593, KAKENHI-PROJECT-21H02706
[Journal Article] WAPL induces cervical intraepithelial neoplasia modulated with estrogen signaling without HPV E6/E7. Oncogene.2021
- Author(s)
  Kumagai K, Takanashi M, Ohno SI, Harada Y, Fujita K, Oikawa K, Sudo K, Ikeda　SI, Nishi H, Oikawa K, Kuroda M.
- Journal Title
  
  Oncogene
  
  Volume: 40(21) Issue: 21 Pages: 3695-3706
- DOI
  10.1038/s41388-021-01787-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08382, KAKENHI-PROJECT-21H02706, KAKENHI-PROJECT-20K09654
[Journal Article] 多様な核内マイクロＲＮＡの機能2019
- Author(s)
  大野慎一郎、黒田雅彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 269 (5) Pages: 337-341
- Data Source
  KAKENHI-PROJECT-18K07048
[Journal Article] rAAV6-mediated miR-29b delivery suppresses renal fibrosis.2019
- Author(s)
  Saito S, Ohno SI, Harada Y, Oikawa K, Fujita K, Mineo S, Gondo A, Kanno Y, KurodaM.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 23 (12) Issue: 12 Pages: 1345-1356
- DOI
  10.1007/s10157-019-01783-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07048, KAKENHI-PROJECT-17H04067, KAKENHI-PROJECT-17K10564, KAKENHI-PROJECT-17K16101
[Journal Article] Difference in immunohistochemical characteristics between Takayasu arteritis and giant cell arteritis: It may be better to distinguish them in the same age2019
- Author(s)
  Kurata Atsushi、Saito Akira、Hashimoto Hirotsugu、Fujita Koji、Ohno Shin-ichiro、Kamma Hiroshi、Nagao Toshitaka、Kobayashi Shigeto、Yamashina Akira、Kuroda Masahiko
- Journal Title
  
  Modern Rheumatology
  
  Volume: 印刷中 Issue: 6 Pages: 1-10
- DOI
  10.1080/14397595.2019.1570999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08705, KAKENHI-PROJECT-17H04067, KAKENHI-PROJECT-16K08675, KAKENHI-PROJECT-17K10564
[Journal Article] Expression level of microRNA-200c is associated with cell morphology in vitro and histological differentiation through regulation of ZEB1/2 and E-cadherin in gastric carcinoma2018
- Author(s)
  Kurata Atsushi、Yamada Masatoshi、Ohno Shin-Ichiro、Inoue Shigeru、Hashimoto Hirotsugu、Fujita Koji、Takanashi Masakatsu、Kuroda Masahiko
- Journal Title
  
  Oncology Reports
  
  Volume: 39 Pages: 91-100
- DOI
  10.3892/or.2017.6093
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08675, KAKENHI-PROJECT-17K10564, KAKENHI-PROJECT-17H04067
[Journal Article] Novel form of miR-29b suppresses bleomycin-induced pulmonary fibrosis.2017
- Author(s)
  Yamada Y, Takanashi M, Sudo K, Ueda S, Ohno SI, Kuroda M.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 2 Pages: 0171957-0171957
- DOI
  10.1371/journal.pone.0171957
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293088, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15K15100, KAKENHI-PROJECT-16K09376, KAKENHI-PROJECT-17H04067
[Journal Article] An improved Red/ET recombineering system and mouse ES cells culture conditions for the generation of targeted mutant mice2017
- Author(s)
  Kumagai K, Takanashi M, Ohno SI, Kuroda M, Sudo K.
- Journal Title
  
  Exp. Anim.
  
  Volume: 66 Issue: 2 Pages: 125-136
- DOI
  10.1538/expanim.16-0075
- NAID
  130005635561
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-16K09376, KAKENHI-PROJECT-17H04067
[Journal Article] Focus on Extracellular Vesicles: Development of Extracellular Vesicle-Based Therapeutic Systems.2016
- Author(s)
  Ohno S, Drummen G, Kuroda M.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 17(2) Issue: 2 Pages: 172-191
- DOI
  10.3390/ijms17020172
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08410, KAKENHI-PROJECT-15K15100, KAKENHI-PROJECT-26293088
[Journal Article] Development of novel small hairpin RNAs that do not require processing by dicer or AGO22016
- Author(s)
  Ohno S, Itano K, Harada Y, Asada K, Oikawa K, Kashiwazako M, Okuyama H, Kumagai K, Takanashi M, Sudo K, Ikeda N, Kuroda M.
- Journal Title
  
  Mol Ther
  
  Volume: 24 Issue: 7 Pages: 1278-1289
- DOI
  10.1038/mt.2016.81
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26250029, KAKENHI-PROJECT-26293088, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15K15100, KAKENHI-PROJECT-15K08410, KAKENHI-PROJECT-16K09376
[Journal Article] エクソソームを用いた治療2014
- Author(s)
  大野慎一郎、黒田雅彦
- Journal Title
  
  Bio Clinica エクソソームによる疾患研究の新展開
  
  Volume: Vo.29 No.6 JUNE 2014 Pages: 34-37
- Data Source
  KAKENHI-PROJECT-25860280
[Journal Article] エクソソームによる核酸DDS2014
- Author(s)
  大野慎一郎、高梨正勝、黒田雅彦
- Journal Title
  
  Drug delivery system
  
  Volume: 第29巻2号 Pages: 30-33
- Data Source
  KAKENHI-PROJECT-25860280
[Journal Article] Roles of exosomes and microvesicles in disease pathogenesis2013
- Author(s)
  Ohno S, Ishikawa A, Kuroda M
- Journal Title
  
  Advanced Drug Delivery Reviews
  
  Volume: 65(3) Issue: 3 Pages: 398-401
- DOI
  10.1016/j.addr.2012.07.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626
[Journal Article] Correlation between number of renal cysts and aortic circumferences measured using autopsy material.2013
- Author(s)
  Kurata A, Inoue S, Ohno S, Nakatsubo R, Takahashi K, Ito T, Kawasaki K, Kokubo R, Sakai T, Ubukata J, Matsubara S, Muraoka R, Yamazaki J, Hirose T, Hojo M, Watanabe E, Kuroda M.
- Journal Title
  
  Pathol Res Pract
  
  Volume: 209 Issue: 7 Pages: 441-447
- DOI
  10.1016/j.prp.2013.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-24590431, KAKENHI-PROJECT-24592039, KAKENHI-PROJECT-25670197
[Journal Article] Identification of a novel role of Septin 10 in Paclitaxel-resistance in cancers through a functional genomics screen2012
- Author(s)
  Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, Ohyashiki J, Kuroda M
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 4 Pages: 821-827
- DOI
  10.1111/j.1349-7006.2012.02221.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592146, KAKENHI-PROJECT-22590367, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23590417, KAKENHI-PROJECT-23590475, KAKENHI-PROJECT-23590993, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-24370058
[Journal Article] Systemically injected exosomes targeted to EGFR deliver anti-tumor microRNA to breast cancer cells2012
- Author(s)
  後藤　典子
- Journal Title
  
  Molecular Therapy
  
  Volume: 21 Issue: 1 Pages: 185-191
- DOI
  10.1038/mt.2012.180
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130009, KAKENHI-PROJECT-23390062, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23590417, KAKENHI-PROJECT-23590993, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626
[Journal Article] TLS-CHOP represses miR-486 expression, inducing upregulation of a metastasis regulator PAI-1 in human myxoid liposarcoma2012
- Author(s)
  N. Borjigin, S. Ohno, W. Wu, M. Tanaka, R. Suzuki, K. Fujita, M. Takanashi, K. Oikawa, T. Goto, T. Motoi, T. Kosaka, K. Yamamoto, M. Kuroda
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 427 Issue: 2 Pages: 355-360
- DOI
  10.1016/j.bbrc.2012.09.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590367, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23590417, KAKENHI-PROJECT-23590993, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626
[Journal Article] Dysregulation of IFN system can lead to poor response to pegylated interferon and ribavirin therapy in chronic hepatitis C.2011
- Author(s)
  Onomoto K, Morimoto S, Kawaguchi T, Toyoda H, Tanaka M, Kuroda M, Uno K, Kumada T, Matsuda F, Shimotohno K, Fujita T, Murakami Y.
- Journal Title
  
  PLoS One.
  
  Volume: 6(5)
- NAID
  120003072107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659626
[Journal Article] The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families.2011
- Author(s)
  Murakami Y, Toyoda H, Tanaka M, Kuroda M, Harada Y, Matsuda F, Tajima A, Kosaka N, Ochiya T, Shimotohno K.
- Journal Title
  
  PLoS One.
  
  Volume: 6(1)
- NAID
  120002871278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659626
[Journal Article] The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families2011
- Author(s)
  Murakami Y, Toyoda H, Tanaka M, Kuroda M, Harada Y, Matsuda F, Tajima A, Kosaka N, Ochiya T, Shimotohno K
- Journal Title
  
  PLoS One
  
  Volume: 6(1) Issue: 1 Pages: e16081-e16081
- DOI
  10.1371/journal.pone.0016081
- NAID
  120002871278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659626
[Journal Article] miR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer2011
- Author(s)
  Tsuchida A, Ohno S, Wu W, Borjigin N, Fujita K, Aoki T, Ueda S, Takanashi M, Kuroda M
- Journal Title
  
  Cancer science
  
  Volume: 102(12) Issue: 12 Pages: 2264-71
- DOI
  10.1111/j.1349-7006.2011.02081.x
- NAID
  10030246362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23659626
[Journal Article] Dysregulation of IFN system can lead to poor response to pegylated interferon and ribavirin therapy in chronic hepatitis C2011
- Author(s)
  Onomoto K, Morimoto S, Kawaguchi T, Toyoda H, Tanaka M, Kuroda M, Uno K, Kumada T, Matsuda F, Shimotohno K, Fujita T, Murakami Y
- Journal Title
  
  PLoS ONE
  
  Volume: 6 Issue: 5 Pages: e19799-e19799
- DOI
  10.1371/journal.pone.0019799
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114004, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-23890029
[Patent] MUC1に結合することを特徴とするにMUC1対する抗体またはその抗原結合断片2017
- Inventor(s)
  黒田　雅彦、藤田　浩司、大野　慎一郎、原田　裕一郎
- Industrial Property Rights Holder
  東京医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] 肝臓特異的DICER1症候群モデルマウスは嚢胞性肝腫瘍を発症する2023
- Author(s)
  大野慎一郎、原田裕一郎、黒田雅彦
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] A mouse model of DICER1 syndrome develops cirrhosis, bile duct hyperplasia and hepatic tumors2022
- Author(s)
  Shinichiro Ohno, Yuichirou Harada, Masahiko Kuroda
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] A mouse model of DICER1 syndrome develops hepatic mesenchymal hamartoma.2022
- Author(s)
  大野慎一郎、原田裕一郞、黒田雅彦
- Organizer
  第１１１回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K06953
[Presentation] Identification of novel mutational signature of precancerous lesions by liquid biopsy using cell-free DNA.2022
- Author(s)
  Tomohiro Umez, Ryohei Kudo, Yoshiki Murakami, Shinichiro Ohno, Yujin Kudo, Norihiko Ikeda, Masahiko Kuroda
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] A mouse model of DICER1 syndrome develops cirrhosis, bile duct hyperplasia and hepatic tumors2022
- Author(s)
  大野慎一郎、原田裕一郞、黒田雅彦
- Organizer
  第８１回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06953
[Presentation] 剖検例冠動脈のDES留置後内膜と、培養平滑筋細胞にrapamycin添加後の、平滑筋分化2022
- Author(s)
  倉田厚、原田裕一郎、藤田浩司、大野慎一郎、高梨正勝、長尾俊孝、黒田雅彦
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K07398
[Presentation] 剖検例のDES留置後内膜、また培養平滑筋細胞にrapamycin添加後の、Calponin発現の上昇2021
- Author(s)
  倉田厚、原田裕一郎、藤田浩司、大野慎一郎、高梨正勝、長尾俊孝、黒田雅彦
- Organizer
  第26回日本血管病理研究会
- Data Source
  KAKENHI-PROJECT-20K07398
[Presentation] Model mice that mimic the genotype of DICER1 syndrome develop hepatic mesenchymal hamartoma.2021
- Author(s)
  大野慎一郎、原田裕一郞、黒田雅彦
- Organizer
  第１１０回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K06953
[Presentation] Model mice that mimic the genotype of DICER1 syndrome develop hepatic mesenchymal hamartoma.2021
- Author(s)
  大野慎一郎、原田裕一郞、黒田雅彦
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] Cisplatin induces differentiation in pluripotent stem cell-derived immature teratoma2021
- Author(s)
  Atsushi Kurata, Masakatsu Takanashi, Shin-ichiro Ohno, Masahiko Kuroda
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07398
[Presentation] 経口投与によるアセロラ果汁由来小胞のDDS担体としての有用性2021
- Author(s)
  梅津知宏、髙梨正勝、大野慎一郎、原田裕一郎、黒田雅彦
- Organizer
  第8回日本細胞外小胞学会 (JSEV)
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] Cisplatin induces differentiation in pluripotent stem cell-derived immature teratoma2021
- Author(s)
  Atsushi Kurata, Masakatsu Takanashi, Shin-ichiro Ohno, Masahiko Kuroda
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] miR-34-AGO-TNRC6A complex transcriptionally up-regulates BLU tumor suppressor via binding of a novel promoter-associated lncRNA in lung cancer2020
- Author(s)
  Shin-ichiro Ohno, Keiki Oikawa, Yuichirou Harada, Masahiko Kuroda
- Organizer
  AACR Annual Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07048
[Presentation] miR-34-AGO complex transcriptionally up-regulate BLU tumor suppressor via binding of novel lncRNA2020
- Author(s)
  大野慎一郎、老川桂生、原田裕一郞、黒田雅彦
- Organizer
  第１０９回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K07048
[Presentation] Development of novel nucleic acid drug targeting KRAS to suppress lung cancer2020
- Author(s)
  Shin-ichiro Ohno, Yuichirou Harada, Masahiko Kuroda
- Organizer
  第７９回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07048
[Presentation] 冠動脈ステント挿入後の内膜平滑筋の成熟度に関する薬剤溶出ステントと従来型ステントの比較2020
- Author(s)
  倉田厚、大野慎一郎、藤田浩司、黒田雅彦
- Organizer
  第25回日本血管病理研究会
- Data Source
  KAKENHI-PROJECT-20K07398
[Presentation] 小児悪性固形腫瘍におけるCD99発現の網羅的検索―抗CD99CAR-T療法適用の観点から―2019
- Author(s)
  渡辺紀子、原田裕一郎、大野慎一郎、藤田浩司、急式政志、柿沼幹男、巾澤温子、黒田雅彦
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] miR-34 familyによる3p21.3領域に存在するがん抑制遺伝子の発現誘導2019
- Author(s)
  大野慎一郎、老川桂生、原田裕一郎、黒田雅彦
- Organizer
  第１０８回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K07048
[Presentation] がん抑制遺伝子BLUのプロモーターから発現するlncRNAはmiR-34-AGO複合体を介してBLUの発現を誘導する2019
- Author(s)
  大野慎一郎、老川桂生、原田裕一郎、黒田雅彦
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] miR-34 familyによる3p21.3領域に存在するがん抑制遺伝子の発現誘導2019
- Author(s)
  大野慎一郎、老川桂生、原田裕一郎、黒田雅彦
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] The novel lncRNA expressed from the promoter of tumor suppressor BLU induces BLU expression via the miR-34-AGO complex.2019
- Author(s)
  大野慎一郎、老川桂生、原田裕一郎、黒田雅彦
- Organizer
  第７８回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07048
[Presentation] アセロラ果汁由来小胞の機能解析とその有用性に関する研究2019
- Author(s)
  梅津知宏、高梨正勝、大野慎一郎、黒田雅彦
- Organizer
  第6回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] miR-34によるがん抑制遺伝子BLUの発現誘導2018
- Author(s)
  大野慎一郎、老川桂生、原田裕一郎、黒田雅彦
- Organizer
  第１０７回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K07048
[Presentation] miR-34によるがん抑制遺伝子BLUの発現誘導2018
- Author(s)
  大野　慎一郎、老川　桂生、原田裕一郎、黒田　雅彦
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] Mir-34aによるがん抑制遺伝子BLUの発現制御機構2018
- Author(s)
  大野慎一郎、三部　芳裕、老川　桂生、原田裕一郎、黒田　雅彦
- Organizer
  第10回日本RNAi研究会、第5回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] Up-regulation pf BLU tumor suppressor by miR-34a2018
- Author(s)
  大野慎一郎、三部　芳裕、弓野　梨紗、老川桂生、原田裕一郎、黒田雅彦
- Organizer
  第１０回日本RNAi研究会
- Data Source
  KAKENHI-PROJECT-18K07048
[Presentation] Up-regulation og BLU tumor suppressor by miR-34 family2018
- Author(s)
  大野慎一郎、黒田　雅彦
- Organizer
  第59回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] miR-34によるがん抑制遺伝子BLUの発現誘導2018
- Author(s)
  大野慎一郎、老川桂生、原田裕一郎、黒田雅彦
- Organizer
  第７７回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18K07048
[Presentation] Establishment of DICER1 syndrome model cells2018
- Author(s)
  老川　桂生、大野慎一郎、黒田　雅彦
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] Up-regulation og BLU tumor suppressor by miR-34 family2018
- Author(s)
  大野慎一郎、老川　桂生、原田裕一郎、黒田　雅彦
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] DICER1症候群モデル細胞の樹立2018
- Author(s)
  老川　桂生、大野慎一郎、黒田　雅彦
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] Mir-34aによるがん抑制遺伝子BLUの発現制御機構2017
- Author(s)
  三部　芳裕、大野　慎一郎、黒田　雅彦
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] RNA干渉に働く短鎖ヘアピンＲＮＡの探索と機能解析2017
- Author(s)
  大野慎一郎、原田裕一郎、村上善基、黒田雅彦
- Organizer
  第１０６回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15K08410
[Presentation] RNA干渉核酸に働く短鎖ヘアピンRNAの探索と機能解析2017
- Author(s)
  大野慎一郎、原田裕一郎、村上善基、黒田雅彦
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] 浸潤性乳管癌に出現するlet-7発現細胞の検討2017
- Author(s)
  鶴井敏光、藤田浩司、大野慎一郎、黒田雅彦
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] Up-regulation of BLU tumor suppuressor by miR-34a2017
- Author(s)
  Sanbu Y、 Ohno S、 Kuroda M
- Organizer
  第9回日本RNAi研究会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] Mir-34aによるがん抑制遺伝子BLUの発現制御機構2017
- Author(s)
  大野慎一郎、三部芳裕、弓野梨紗、老川桂生、原田裕一郞、黒田雅彦
- Organizer
  第７６回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K08410
[Presentation] AAV-mediated miRNA-29b delivary suppuress renal fibrosis2017
- Author(s)
  Saito S、Ohno S、 Harada Y、 Oikawa K、 Kanno Y、 Kuroda M
- Organizer
  第9回日本RNAi研究会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] miRNA生成経路を欠損する肺がん細胞株の解析2017
- Author(s)
  老川桂生、淺田浩太朗、大野慎一郎、黒田雅彦
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] 子宮頸部上皮内腫瘍病変に対する新規モノクロナール抗体の開発2017
- Author(s)
  藤田浩司、大野慎一郎、西　洋孝、井坂恵一、黒田雅彦
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17H04067
[Presentation] Search and characterization of novel hairpin RNAs acting on RNA interference2017
- Author(s)
  大野慎一郎、原田裕一郎、村上善基、黒田雅彦
- Organizer
  第６回医薬工シンポジウム
- Data Source
  KAKENHI-PROJECT-15K08410
[Presentation] Up-regulation of BLU tumor suppressor by miR-34a.2017
- Author(s)
  三部芳裕、大野慎一郎、黒田雅彦
- Organizer
  第９回日本RNAi研究会
- Data Source
  KAKENHI-PROJECT-15K08410
[Presentation] Development of novel Dicer- and Ago2-independent small hairpin RNAs.2016
- Author(s)
  Shin-ichiro OHNO, Karen ITANO, Yuichirou HARADA, Koutaro ASADA, Keiki OIKAWA, Mikie KASHIWAZAKO, Hikaru OKUYAMA, Katsuyoshi KUMAGAI, Masakatsu TAKANASHI, Katsuko SUDO, Norihiko IKEDA, Masahiko KURODA.
- Organizer
  ASGCT 19th Annual Meeting 2016
- Place of Presentation
  Marriott Wardman Park, Washington, DC, USA.
- Year and Date
  2016-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08410
[Presentation] 肺がん治療を想定した副作用の少ない短鎖型新規核酸医薬の開発2015
- Author(s)
  大野慎一郎、板野華連、原田裕一郎、浅田浩太朗、老川桂生、柏迫幹絵、高梨正勝、須藤カツ子、池田徳彦、黒田雅彦
- Organizer
  第１０４回日本病理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-15K08410
[Presentation] 副作用を軽減した短鎖型核酸医薬の開発2015
- Author(s)
  大野慎一郎、板野華連、浅田浩太朗、老川桂生、柏迫幹絵、高梨正勝、黒田雅彦
- Organizer
  第７回日本RNAi研究会
- Place of Presentation
  広島プリンスホテル
- Year and Date
  2015-08-26
- Data Source
  KAKENHI-PROJECT-15K08410
[Presentation] 肺がんを効果的に抑制するMimic microRNAの新規形状の探索2014
- Author(s)
  大野慎一郎、板野華連、原田裕一郎、高梨正勝、須藤カツ子、黒田雅彦
- Organizer
  第１０３回日本病理学会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-25860280
[Presentation] ユーイング肉腫における新規構成RNAによるキメラがん遺伝子ノックダウン効果の検証2013
- Author(s)
  原田裕一郎、大野慎一郎、大木忠明、水谷隆之、須藤カツ子、高梨正勝、黒田雅彦
- Organizer
  第５回　日本RNA研究会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] 胃癌細胞株における上皮間葉移行に関与するマイクロRNAとその標的の検出2013
- Author(s)
  倉田厚、山田正俊、橋本浩次、呉偉紅、那日蘇、藤田浩司、大野慎一郎、高梨正勝、黒田雅彦
- Organizer
  第102回　日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] Lung cancer miRNA replacement therapy using novel class of miRNA2013
- Author(s)
  S Ohno, K Itano, Y Harada, M Takanashi, K Sudo, T Mizutani, M Kuroda.
- Organizer
  アメリカ癌学会国際会議分子標的とがん治療
- Place of Presentation
  Boston､ MA, USA
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] 前立腺癌におけるmicroRNA-200c の発現解析2013
- Author(s)
  山田正俊、大野慎一郎、藤田浩司、倉田厚、黒田雅彦
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] 高効率にがん抑制効果を発揮するmiR-34aの新規形状の探索2013
- Author(s)
  大野慎一郎、板野華連、柏迫幹絵、大木忠明、水谷隆之、須藤カツ子、高梨正勝、黒田雅彦
- Organizer
  第５回　日本RNA研究会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] 前立腺癌におけるmicroRNA-200cの発現解析2013
- Author(s)
  山田正俊、大野慎一郎、藤田浩司、倉田厚、黒田雅彦
- Organizer
  第102回　日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] 高効率にがん抑制効果を発揮するmiR-34aの新規形状の探索2013
- Author(s)
  大野慎一郎、板野華蓮、柏迫幹絵、大木忠明、水谷隆之、須藤カツ子、高梨正勝、黒田雅彦
- Organizer
  第５回日本RNAi研究会
- Place of Presentation
  グランドプリンスホテル広島
- Data Source
  KAKENHI-PROJECT-25860280
[Presentation] Lung cancer miRNA replacement therapy using novel class of miRNA2013
- Author(s)
  Shin-ichiro Ohno, Karen Itano, Masakatsu Takanashi, Katsuko Sudo, Masahiko Kuroda
- Organizer
  AACR-NCI-EORTC 　International Conference on Molecular Targets and Cancer Therapeutics
- Place of Presentation
  Hynes Convention Center, Boston､ MA､USA
- Data Source
  KAKENHI-PROJECT-25860280
[Presentation] Systemically injected exosomes targeted to EGFR deliver anti-tumor microRNA to breast cancer cells2013
- Author(s)
  Ohno S, Takanashi M, Ohgi T, Mizutani T, Murakami Y, Kuroda M
- Organizer
  Keystone Symposia Conference - Noncoding RNAs in Development and Cancer(A7)
- Place of Presentation
  Vancouver, British Columbia, CANADA
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] Systemically injected exosomes targeted to EGFR deliver anti-tumor microRNA to breast cancer cells.2013
- Author(s)
  Shinichiro Ohno, Masakatsu Takanashi, Tadaaki Ohgi, Takayuki Mizutani, Yoshiki Murakami, Masahiko Kuroda.
- Organizer
  Keystone Symposia Conference
- Place of Presentation
  Vancouver, British Columbia, CANADA
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] EGFRリガンド発現エクソソームを用いた新規ドラッグデリバリーシステムの開発2012
- Author(s)
  大野慎一郎、上田しのぶ、石川章夫、松山永久、藤田浩司、高梨正勝、黒田雅彦
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] Selective target delivery of miRNA using EGF expressing exosomes2012
- Author(s)
  Shinichiro Ohno, Masakatsu Takanashi, Shinobu Ueda, Tadaaki Ohgi, Takayuki Mizutani, Masahiko Kuroda
- Organizer
  Keystone symposia Nucleic Acid Therapeutics: From Base Pairs to Bedsides (A2)
- Place of Presentation
  Santa Fe, New Mexico
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] 胃低分化癌におけるin situ hybridization法を用いたmiRNA-92aおよび200cの発現低下の意義2012
- Author(s)
  倉田厚、呉偉紅、山田正俊、那日蘇、藤田浩司、大野慎一郎、高梨正勝、黒田雅彦
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] EGFR リガンド発現エクソソームを用いた新規ドラッグデリバリーシステムの開発2012
- Author(s)
  大野慎一郎、上田しのぶ、石川章夫、松山永久、藤田浩司、高梨正勝、黒田雅彦
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] Selective target delivery of miRNA using EGF expressing exosomes2012
- Author(s)
  Ohno S, Takanashi M, Ueda S, Ohgi T, Mizutani T, Kuroda M
- Organizer
  Keystone symposia Nucleic Acid Therapeutics : From Base Pairs to Bedsides (A2)
- Place of Presentation
  Santa Fe, New Mexico
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] マウスに経口投与したエクソソームの生体内での安定性と分布2012
- Author(s)
  髙梨正勝、須藤カツ子、大野慎一郎、上田しのぶ、石川章夫、黒田雅彦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] TLS-CHOPがん遺伝子が発現制御するmiRNAの解析2012
- Author(s)
  ボルジゲン那日蘇、大野慎一郎、田中正視、呉偉紅、田中理英子、藤田浩司、高梨正勝、黒田雅彦
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] マウスに経口投与したエクソソームの生体内での安定性と分布．2012
- Author(s)
  髙梨　正勝、須藤　カツ子、大野　慎一郎、上田　しのぶ、石川　章夫、黒田　雅彦．
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] Delivery of miRNA to the EGFR-expressed tumor by systemic injection of target exosomes2012
- Author(s)
  Ohno S, Takanashi M, Sudo K, Mizutani T, Ochiya T, Kuroda M
- Organizer
  International Society for the EGFR-extracellular Vesicled (ISEV)
- Place of Presentation
  Gothenburg, Sweden
- Year and Date
  2012-04-18
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] Delivery of antitumor molecules to the EGFR expressing cancer using EGF expressing exosomes2011
- Author(s)
  大野　慎一郎、上田　しのぶ、石川　章夫、藤田　浩司、高梨　正勝、黒田　雅彦
- Organizer
  第３７回分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] リガンド修飾エクソソームによるEGF receptor発現細胞を標的としたドラッグデリバリーシステムの開発2011
- Author(s)
  大野　慎一郎、上田　しのぶ、石川　章夫、松山　永久、高梨　正勝、黒田　雅彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] 人工型exosomeの生体内分布と安定性についての研究2011
- Author(s)
  高梨　正勝、須藤　カツ子、大野　慎一郎、上田　しのぶ、石川　章夫、黒田　雅彦
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] CD63-GFP を発現したエクソソームのマウス生体内での安定性と分布について2011
- Author(s)
  高梨正勝、須藤カツ子、大野慎一郎、上田しのぶ、石川章夫、黒田雅彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] CD63-GFPを発現したエクソソームのマウス生体内での安定性と分布について2011
- Author(s)
  高梨　正勝、須藤　カツ子、大野　慎一郎、上田　しのぶ、石川　章夫、黒田　雅彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] 人工型exosome の生体内分布と安定性についての研究2011
- Author(s)
  高梨正勝、須藤カツ子、大野慎一郎、上田しのぶ、石川章夫、黒田雅彦
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] Delivery of antitumor molecules to the EGFR expressing cancer using EGF expressing exosomes2011
- Author(s)
  大野慎一郎、上田しのぶ、石川章夫、藤田浩司、高梨正勝、黒田雅彦
- Organizer
  第37回分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] リガンド修飾エクソソームによるEGFreceptor 発現細胞を標的としたドラッグデリバリーシステムの開発2011
- Author(s)
  大野慎一郎、上田しのぶ、石川章夫、松山永久、高梨正勝、黒田雅彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659626
[Presentation] がんを効果的に抑制する短縮型Mimic microRNAの開発
- Author(s)
  大野慎一郎、板野華連、原田裕一郎、高梨正勝、須藤カツ子、黒田雅彦
- Organizer
  第３３回分子病理学研究会
- Place of Presentation
  宮城蔵王ロイヤルホテル
- Year and Date
  2014-07-25 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-25860280
[Presentation] 肺がんを標的とする短縮型Mimic microRNAの開発
- Author(s)
  大野慎一郎、原田裕一郎、板野華連、浅田浩太朗、老川桂生、高梨正勝、須藤カツ子、黒田雅彦
- Organizer
  第６回日本RNAi研究会
- Place of Presentation
  広島プリンスホテル
- Year and Date
  2014-08-28 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-25860280
[Presentation] 肺がんを効果的に抑制するMimic microRNAの新規形状の探索
- Author(s)
  大野慎一郎、板野華連、原田裕一郎、高梨正勝、須藤カツ子、池田徳彦、黒田雅彦
- Organizer
  第５５回日本肺がん学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2014-11-14 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25860280
[Presentation] The development of short form of mimic microRNA for lung cancer therapy
- Author(s)
  Shin-ichiro OHNO, Karen ITANO, Yuichirou HARADA, Masakatsu TAKANASHI, Katsuko SUDO, Norihiko IKEDA, Masahiko KURODA
- Organizer
  第７３回日本癌学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25860280

1. KURODA Masahiko (80251304)

# of Collaborated Projects: 8 results

# of Collaborated Products: 89 results
2. 原田裕一郎 (80570168)

# of Collaborated Projects: 5 results

# of Collaborated Products: 18 results
3. 熊谷勝義 (20567911)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. 須藤カツ子 (50126091)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. TAKANASHI Masakatsu (80312007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
6. UEDA Shinobu (00521874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
7. TSUCHIDA Akihiko (50207396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Kurata Atsushi (10302689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. 西洋孝 (60307345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 梅津知宏 (40385547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. ISAKA Keiichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. MURAKAMI Yoshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. OIKAWA Kosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 長尾俊孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 後藤典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 下遠野邦忠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 助田葵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohno Shin-ichiro 大野 慎一郎

OHNO Shinichiro 大野 慎一郎

Research Projects

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Development of DICER1 syndrome model micePrincipal Investigator

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Analysis of the mechanism of ncRNA-mediated carcinogenesis using the DICER1 syndrome model

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RNA activationにおける分子機構の解析Principal Investigator

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Does smooth muscle maturation, an indicator of plaque stabilization, also appear in the intima after drug-eluting stent placement?

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子宮頸癌の新規予防法開発

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Exploration and functional analysis of novel RNA-interfering nucleic acids.Principal Investigator

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Identification of novel non-coding RNA

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Development of novel form of mimic microRNA for microRNA replacement therapy.Principal Investigator

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Development of novel nucleic acid drugs for chronic hepatitis C virus infectionPrincipal Investigator

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Development of a new miRNA delivery system for targeting cancer stem cells

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アレルギー体質関連遺伝子の同定Principal Investigator

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[Book] 新たなドラッグデリバリーシステムとしてのエクソソーム.細胞工学2013

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[Journal Article] MiR-34a induces myofibroblast differentiation from renal fibroblasts.2023

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Ohno Shin-ichiro 大野慎一郎

OHNO Shinichiro 大野慎一郎