Saigusa Daisuke 三枝大輔

… Alternative Names

SAIGUSA Daisuke 三枝大輔

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Researcher Number	90545237
Other IDs
Affiliation (Current)	2025: 帝京大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 帝京大学, 薬学部, 准教授 2015 – 2022: 東北大学, 東北メディカル・メガバンク機構, 講師 2017: 東北大学, 東北メディカル・メガバンク機構, 助教 2013 – 2014: 東北大学, 東北メディカル・メガバンク機構, 助教
Review Section/Research Field	Principal Investigator Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related Except Principal Investigator Basic Section 56060:Ophthalmology-related / Basic Section 47060:Clinical pharmacy-related / General medical chemistry / Basic Section 59040:Nutrition science and health science-related / Basic Section 46010:Neuroscience-general-related / Ophthalmology / Respiratory organ internal medicine / General physiology / Earth and planetary science and related fields
Keywords	Principal Investigator スフィンゴ脂質 / S1P / 質量分析計 / MSイメージング / MALDI / IMS / LC-MS/MS / ヒートスタビライザー / レーザーマイクロダイセクション / 細胞外小胞 … More / 誘導体化 / 一細胞 / MSイメージング法 / 肝癌 / イメージング MS / イオンモビリティ / スフィンゴシン一リン酸 / DIUTHAME / DESI / 立体可視化 / 組織切片 / イメージングMS / 粘着性導電性フィルム / 凍結組織切片 / メタボローム解析 / ジルコニア / 固相抽出カラム / S1Pトランスポーター / 原子間力顕微鏡 / 微量組織切片 / LC/MS/MS / リゾリン脂質 … More Except Principal Investigator 緑内障 / 血液脳関門 / メタボローム解析 / 慢性腎臓病 / 質量分析 / 細胞内代謝 / 認知機能障害 / サルコペニア / CKD / 高齢化社会 / トランスポーター / qGAP法 / 異なる中枢関門 / 薬物分布の脳内部位差 / 脳内薬物動態 / プロテオミクス / 血液脳脊髄液関門 / 血液クモ膜関門 / neuronal development / neuronal polarity / sphingolipid / VLCFAs / lipid rafts / トランス臣クス / 線維柱帯 / プロテオーム解析 / リピドーム解析 / 眼圧 / 細胞外小胞 / リピドミクス / Glaucoma / OLSA / SWATH / 中枢関門創薬 / 中枢関門(原因)仮説 / バリアーシステム生物学 / 中枢関門 / バイオマーカー / メタボロミクス / フェノタイプ / 新規バイオマーカー / メタボロミクス解析 / マクロファージ / 赤血球 / Bach1 / ヘム / 酸塩基平衡 / 体液 / 腎 / 重炭酸 / クエン酸 / 尿毒症物質 / 経口アルカリ性化剤 / アルカリ性化剤 / 酸性尿 / 有機物 / 分布 / イメージング質量分析計 / アミノ酸 / イメージング / 質量分析計 / 有機分子 / 隕石 / コンディショナルノックダウン / DNAメチル化 / ヒストンメチル化 / SAM合成酵素 / エピジェネティクス Less

Investigating the pathogenesis of normal tension glaucoma caused by ocular blood flow insufficiency using non-human primates.
- Principal Investigator
  
  佐藤孝太
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
The Mechanism of Lipid Raft Formation Steering Neuronal Polarity Determination via Very-Long-Chain Fatty Acids
- Principal Investigator
  
  本多敦子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Niigata University
投影型MSイメージング法による脂質ラフト含有スフィンゴ脂質の可視化技術開発Principal Investigator
- Principal Investigator
  
  三枝大輔
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Teikyo University
Elucidation of spatio-temporal regulation mechanisms of brain pharmacokinetics by blood-brain, arachnoid and cerebrospinal fluid barriers
- Principal Investigator
  
  内田康雄
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Hiroshima University
尿毒素による細胞内代謝失調を標的とした高齢者の慢性腎臓病合併症の治療開発
- Principal Investigator
  
  佐藤恵美子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tohoku University
Comprehensive mechanism of elevated intraocular pressure by trans-omics analysis among anterior segment tissues.
- Principal Investigator
  
  Yokoyama Yu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
Distribution analysis of S1P on tissue sections by high resolution MS imagingPrincipal Investigator
- Principal Investigator
  
  Saigusa Daisuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Teikyo University
  Tohoku University
Establishment of CNS barrier-targeted drug development based on generation of a new field, Barrier Systems Biology
- Principal Investigator
  
  Uchida Yasuo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tohoku University
Development of tree-dimensional MS imaging for sphingolipidsPrincipal Investigator
- Principal Investigator
  
  Saigusa Daisuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tohoku University
Investigation on imaging of distribution of organic molecules in meteorites
- Principal Investigator
  
  Furukawa Yoshihiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Earth and planetary science and related fields
- Research Institution
  Tohoku University
Construction of integrated glaucoma database and discovery of glaucoma biomarker by metabolomics
- Principal Investigator
  
  Nakazawa Toru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tohoku University
Reno-protective mechanism by therapeutic intervention of metabolic acidosis on chronic kidney disease
- Principal Investigator
  
  Abe Michiaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Tohoku University
Development of a method for distribution analysis of sphingolipids in tissue by mass spectrometryPrincipal Investigator
- Principal Investigator
  
  Saigusa Daisuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tohoku University
Regulation of erythropoiesis and macrophages by the heme signal
- Principal Investigator
  
  IGARASHI Kazuhiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
New biomarkers for sarcoidosis by metabolomics analysis using plasma and urine from patients.
- Principal Investigator
  
  Muramatsu Soshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Development of determination method for lysophospholipids by LC/MS/MSPrincipal Investigator
- Principal Investigator
  
  SAIGUSA Daisuke
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tohoku University
Methods rewriting epigenome as the target of methyonine adenosyltransferase II
- Principal Investigator
  
  KATOH Yasutake
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University

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All Journal Article Presentation Book Patent

[Book] 「腎臓のサイエンス」腎臓のバイオマーカーと創薬戦略、実験医学2016
- Author(s)
  鈴木健弘、三島英換、三枝大輔
- Total Pages
  1355
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K18842
[Book] 最新生理活性脂質研究－実験手法、基礎的知識とその応用－2013
- Author(s)
  富岡佳久、鈴木直人、三枝大輔
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-25860021
[Journal Article] Exploration of urine metabolic biomarkers for new-onset, untreated pediatric epilepsy: A gas and liquid chromatography mass spectrometry-based metabolomics study2024
- Author(s)
  Akiyama Tomoyuki、Saigusa Daisuke、Inoue Takushi、Tokorodani Chiho、Akiyama Mari、Michiue Rie、Mori Atsushi、Hishinuma Eiji、Matsukawa Naomi、Shibata Takashi、Tsuchiya Hiroki、Kobayashi Katsuhiro
- Journal Title
  
  Brain and Development
  
  Volume: 46 Issue: 4 Pages: 180
- DOI
  10.1016/j.braindev.2023.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27316
[Journal Article] Dietary habits and plasma lipid concentrations in a general Japanese population2024
- Author(s)
  Sato Mitsuharu、Hishinuma Eiji、Matsukawa Naomi、Shima Yoshiko、Saigusa Daisuke、Motoike Ikuko N.、Kogure Mana、Nakaya Naoki、Hozawa Atsushi、Kuriyama Shinichi、Yamamoto Masayuki、Koshiba Seizo、Kinoshita Kengo
- Journal Title
  
  Metabolomics
  
  Volume: 20 Issue: 2
- DOI
  10.1007/s11306-024-02087-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27316
[Journal Article] Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment2023
- Author(s)
  Tatara Y, Yamazaki H, Katsuoka F, Chiba M, Saigusa D, Kasai S, Nakamura T, Inoue J, Aoki Y, Shoji M, Motoike I, Tamada Y, Hashizume K, Shoji M, Kinoshita K, Murashita K, Nakaji S, Yamamoto M, Itoh K.
- Journal Title
  
  Current Research in Translational Medicine.
  
  Volume: 71 Issue: 1 Pages: 103367-103367
- DOI
  10.1016/j.retram.2022.103367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08432, KAKENHI-PROJECT-21H04844, KAKENHI-PROJECT-20H03374
[Journal Article] Comprehensive study of metabolic changes induced by a ketogenic diet therapy using GC/MS- and LC/MS-based metabolomics2023
- Author(s)
  Akiyama Mari、Akiyama Tomoyuki、Saigusa Daisuke、Hishinuma Eiji、Matsukawa Naomi、Shibata Takashi、Tsuchiya Hiroki、Mori Atsushi、Fujii Yuji、Mogami Yukiko、Tokorodani Chiho、Kuwahara Kozue、Numata-Uematsu Yurika、Inoue Kenji、Kobayashi Katsuhiro
- Journal Title
  
  Seizure: European Journal of Epilepsy
  
  Volume: 107 Pages: 52
- DOI
  10.1016/j.seizure.2023.03.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27316
[Journal Article] Metabolic profiling by integrated analysis with LC-MS and MSI2023
- Author(s)
  Daisuke Saigusa
- Journal Title
  
  Medical Mass Spectrometry
  
  Volume: 7 Pages: 2-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27316
[Journal Article] Decreased β-hydroxybutyrate and ketogenic amino acid levels in depressed human adults2023
- Author(s)
  Sato Shiho、Yu Zhiqian、Sakai Mai、Motoike Ikuko N.、Saigusa Daisuke、Hirayama Ryo、Kikuchi Yoshie、Abe Takaaki、Kinoshita Kengo、Koshiba Seizo、Tomita Hiroaki
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 57 Issue: 6 Pages: 1018
- DOI
  10.1111/ejn.15931
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-20K07962
[Journal Article] Identification of predictive biomarkers for endometrial cancer diagnosis and treatment response monitoring using plasma metabolome profiling2023
- Author(s)
  Hishinuma Eiji、Shimada Muneaki、Matsukawa Naomi、Shima Yoshiko、Li Bin、Motoike Ikuko N.、Shibuya Yusuke、Hagihara Tatsuya、Shigeta Shogo、Tokunaga Hideki、Saigusa Daisuke、Kinoshita Kengo、Koshiba Seizo、Yaegashi Nobuo
- Journal Title
  
  Cancer & Metabolism
  
  Volume: 11 Issue: 1
- DOI
  10.1186/s40170-023-00317-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09486, KAKENHI-PROJECT-21K09531, KAKENHI-PROJECT-23K24478, KAKENHI-PROJECT-23K27316
[Journal Article] Local Delivery of Nimustine Hydrochloride against Brain Tumors: Basic Characterization Study2023
- Author(s)
  Shao Xiaodong、Saito Ryuta、Sato Aya、Okuno Saori、Saigusa Daisuke、Saito Ritsumi、Uruno Akira、Osada Yoshinari、Kanamori Masayuki、Tominaga Teiji
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 261 Issue: 3 Pages: 187-194
- DOI
  10.1620/tjem.2023.J069
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03039, KAKENHI-PROJECT-23K27316
[Journal Article] Improving the Signal Intensity of Cryosections Using a Conductive Adhesive Film in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging2023
- Author(s)
  Saigusa Daisuke、Saito Ritsumi、Kawamoto Komei、Uruno Akira、Kano Kuniyuki、Shimma Shuichi、Aoki Junken、Yamamoto Masayuki、Kawamoto Tadafumi
- Journal Title
  
  Mass Spectrometry
  
  Volume: 12 Issue: 1 Pages: A0137-A0137
- DOI
  10.5702/massspectrometry.A0137
- ISSN
  2186-5116, 2187-137X
- Year and Date
  2023-12-12
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-23K27316
[Journal Article] Reduced glutathione level in the aqueous humor of patients with primary open-angle glaucoma and normal-tension glaucoma2023
- Author(s)
  Sato Kota、Saigusa Daisuke、Kokubun Taiki、Fujioka Amane、Feng Qiwei、Saito Ritsumi、Uruno Akira、Matsukawa Naomi、Ohno-Oishi Michiko、Kunikata Hiroshi、Yokoyama Yu、Yasuda Masayuki、Himori Noriko、Omodaka Kazuko、Tsuda Satoru、Maekawa Shigeto、Yamamoto Masayuki、Nakazawa Toru
- Journal Title
  
  npj Aging
  
  Volume: 9 Issue: 1 Pages: 28-28
- DOI
  10.1038/s41514-023-00124-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-23K27316
[Journal Article] Identification of predictive biomarkers for diagnosis and radiation sensitivity of uterine cervical cancer using wide-targeted metabolomics2023
- Author(s)
  Hishinuma Eiji、Shimada Muneaki、Matsukawa Naomi、Li Bin、Motoike Ikuko N.、Hagihara Tatsuya、Shigeta Shogo、Tokunaga Hideki、Saigusa Daisuke、Kinoshita Kengo、Koshiba Seizo、Yaegashi Nobuo
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research
  
  Volume: 49 Issue: 8 Pages: 2109
- DOI
  10.1111/jog.15709
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09486, KAKENHI-PROJECT-21K09531, KAKENHI-PROJECT-23K24478, KAKENHI-PROJECT-23K27316
[Journal Article] Distributions of CHN compounds in meteorites record organic syntheses in the early solar system2023
- Author(s)
  Furukawa Yoshihiro、Saigusa Daisuke、Kano Kuniyuki、Uruno Akira、Saito Ritsumi、Ito Motoo、Matsumoto Megumi、Aoki Junken、Yamamoto Masayuki、Nakamura Tomoki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-023-33595-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-23K27316
[Journal Article] Lysophosphatidic acid receptor1/3 antagonist inhibits the activation of satellite glial cells and reduces acute nociceptive responses2022
- Author(s)
 Hoshino Yoko、Okuno Toshiaki、Saigusa Daisuke、Kano Kuniyuki、Yamamoto Shota、Shindou Hideo、Aoki Junken、Uchida Kanji、Yokomizo Takehiko、Ito Nobuko
- Journal Title
 
 The FASEB Journal
 
 Volume: 36 Issue: 4
- DOI
 10.1096/fj.202101678r
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-20K09190, KAKENHI-PROJECT-21K15309, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-22KJ3239, KAKENHI-PROJECT-22K06888, KAKENHI-PROJECT-23K24425
[Journal Article] Plasma metabolic disturbances during pregnancy and postpartum in women with depression2022
- Author(s)
  Z Yu, N Matsukawa, D Saigusa, I. N. Motoike, C Ono, Y Okamura, T Onuma, Y Takahashi, M Sakai, H Kudo, T Obara, K Murakami, M Shirota, S Kikuchi, N Kobayashi, Y Kikuchi, J Sugawara, N Minegishi, S Ogishima, K Kinoshita, M Yamamoto, N Yaegashi, S Kuriyama, S Koshiba, H Tomita
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 12 Pages: 105666-105666
- DOI
  10.1016/j.isci.2022.105666
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15742, KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-20K07962, KAKENHI-PROJECT-21H03537
[Journal Article] Urine autotaxin levels reflect the disease activity of sarcoidosis2022
- Author(s)
  Murakami Koji、Tamada Tsutomu、Saigusa Daisuke、Miyauchi Eisaku、Nara Masayuki、Ichinose Masakazu、Kurano Makoto、Yatomi Yutaka、Sugiura Hisatoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 4372-4372
- DOI
  10.1038/s41598-022-08388-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-21K08148, KAKENHI-PROJECT-20H03684
[Journal Article] Modulations of bioactive lipids and their receptors in postmortem Alzheimer’s disease brains2022
- Author(s)
  Kurano Makoto、Saito Yuko、Uranbileg Baasanjav、Saigusa Daisuke、Kano Kuniyuki、Aoki Junken、Yatomi Yutaka
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 14 Pages: 1066578-1066594
- DOI
  10.3389/fnagi.2022.1066578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-20H03573, KAKENHI-PROJECT-19H03366, KAKENHI-PROJECT-22H04923
[Journal Article] Dynamic modulations of urinary sphingolipid and glycerophospholipid levels in COVID-19 and correlations with COVID-19-associated kidney injuries2022
- Author(s)
  Kurano Makoto、Jubishi Daisuke、Okamoto Koh、Hashimoto Hideki、Sakai Eri、Morita Yoshifumi、Saigusa Daisuke、Kano Kuniyuki、Aoki Junken、Harada Sohei、Okugawa Shu、Doi Kent、Moriya Kyoji、Yatomi Yutaka
- Journal Title
  
  Journal of Biomedical Science
  
  Volume: 29 Issue: 1 Pages: 1069-1087
- DOI
  10.1186/s12929-022-00880-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-20H03573
[Journal Article] Lipidomic and metabolic profiling of plasma and plasma-derived extracellular vesicles by UHPLC-MS/MS2022
- Author(s)
  Daisuke Saigusa、Takeshi Honda、Yuko Iwasaki、Koji Ueda、Eiji Hishinuma、Naomi Matsukawa、Akira Togashi、Noriyuki Matsutani、Nobuhiko Seki
- Journal Title
  
  Medical Mass Spectrometry
  
  Volume: 6 Issue: 2 Pages: 126-137
- DOI
  10.24508/mms.2022.11.007
- ISSN
  2432-7441, 2432-745X
- Year and Date
  2022-11-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374
[Journal Article] Gene expression changes related to bone mineralization, blood pressure and lipid metabolism in mouse kidneys after space travel2022
- Author(s)
  Suzuki Norio、Iwamura Yuma、Nakai Taku、Kato Koichiro、Otsuki Akihito、Uruno Akira、Saigusa Daisuke、Taguchi Keiko、Suzuki Mikiko、Shimizu Ritsuko、Yumoto Akane、Okada Risa、Shirakawa Masaki、Shiba Dai、Takahashi Satoru、Suzuki Takafumi、Yamamoto Masayuki
- Journal Title
  
  Kidney International
  
  Volume: 101 Issue: 1 Pages: 92
- DOI
  10.1016/j.kint.2021.09.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-17KK0183, KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-21J21975, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-23K21372
[Journal Article] Codon Usage and mRNA Stability are Translational Determinants of Cellular Response to Canonical Ferroptosis Inducers2022
- Author(s)
  Rashad Sherif、Byrne Shane R、Saigusa Daisuke、Xiang Jingdong、Zhou Yuan、Zhang Liyin、Begley Thomas J、Tominaga Teiji、Niizuma Kuniyasu
- Journal Title
  
  Neuroscience
  
  Volume: 501 Pages: 103-130
- DOI
  10.1016/j.neuroscience.2022.08.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-20K16323, KAKENHI-PROJECT-20KK0338
[Journal Article] Metabolic and Epigenetic Regulation of SMAD7 by STC1 Ameliorates Lung Fibrosis2022
- Author(s)
  Ohkouchi Shinya、Kanehira Masahiko、Saigusa Daisuke、Ono Manabu、Tazawa Ryushi、Terunuma Hideya、Hirano Taizou、Numakura Tadahisa、Notsuda Hirotsugu、Inoue Chihiro、Saito-Koyama Ryoko、Tabata Masao、Irokawa Toshiya、Ogawa Hiromasa、Kurosawa Hajime、Okada Yoshinori
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology
  
  Volume: 67 Issue: 3 Pages: 320
- DOI
  10.1165/rcmb.2021-0445oc
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-20H03686, KAKENHI-PROJECT-22K08250
[Journal Article] Quantification of threonine-containing lysophospholipids using ESI-LC-MS/MS in mouse tissues2022
- Author(s)
  Michiyo Okudaira、Kuniyuki Kano、Kumiko Makide、Daisuke Saigusa、Tomohiko Ohwada、Junken Aoki
- Journal Title
  
  Medical Mass Spectrometry
  
  Volume: 6 Issue: 2 Pages: 138-148
- DOI
  10.24508/mms.2022.11.008
- ISSN
  2432-7441, 2432-745X
- Year and Date
  2022-11-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374
[Journal Article] Nrf2 plays a critical role in the metabolic response during and after spaceflight2021
- Author(s)
  Uruno A、Saigusa D、Suzuki T、Yumoto A、Nakamura T、Matsukawa N、Yamazaki T、Saito R、Taguchi K、Suzuki M、Suzuki N、Otsuki A、Katsuoka F、Hishinuma E、Okada R、Koshiba S、Tomioka Y、Shimizu R、Shirakawa M、Kensler TW.、Shiba D、Yamamoto M
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1381
- DOI
  10.1038/s42003-021-02904-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H03555, KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-23K21372
[Journal Article] Development of an on-tissue derivatization method for MALDI mass spectrometry imaging of bioactive lipids containing phosphate monoester using Phos-Tag2021
- Author(s)
  Iwama Taiga、Kano Kuniyuki、Saigusa Daisuke、Ekroos Kim、van Echten-Deckert Gerhild、Vogt Johannes、Aoki Junken
- Journal Title
  
  Analytical Chemistry
  
  Volume: 93 Issue: 8 Pages: 3867
- DOI
  10.1021/acs.analchem.0c04479
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-20K21379, KAKENHI-PROJECT-20H03374
[Journal Article] Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells2021
- Author(s)
  Tamako Nishimura*, Takuya Oyama*, Hooi Ting Hu*, Toshifumi Fujioka* et al.(*:equally contributed)
- Journal Title
  
  Developmental Cell
  
  Volume: 56 Issue: 6 Pages: 842
- DOI
  10.1016/j.devcel.2021.02.029
- NAID
  120007172296
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06625, KAKENHI-PROJECT-18H03533, KAKENHI-PROJECT-20H03252, KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-19K22576, KAKENHI-PROJECT-19K16145, KAKENHI-PROJECT-19K06639, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H03456, KAKENHI-PLANNED-18H05493
[Journal Article] Comparison of kit-based metabolomics with other methodologies in a large cohort, towards establishing reference values2021
- Author(s)
  Saigusa D*, Hishinuma E, Matsukawa N, Takahashi M, Inoue J, Tadaka S, Motoike I N, Hozawa A, Izumi Y, Bamba T, Kinoshita K, Ekroos K, Koshiba S, Yamamoto M.
- Journal Title
  
  Metabolites
  
  Volume: 11 Issue: 10 Pages: 652-652
- DOI
  10.3390/metabo11100652
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05167, KAKENHI-PLANNED-17H06304, KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-17K07298
[Journal Article] Identification and Validation of Combination Plasma Biomarker of Afamin, Fibronectin and Sex Hormone-Binding Globulin to Predict Pre-eclampsia2021
- Author(s)
  Uchida Y, Higuchi T, Shirota M, Kagami S, Saigusa D, Koshiba S, Yasuda J, Tamiya G, Kuriyama S, Kinoshita K, Yaegashi N, Yamamoto M, Terasaki T, Sugawara J
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 6 Pages: 804-815
- DOI
  10.1248/bpb.b20-01043
- NAID
  130008046709
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H05495, KAKENHI-PUBLICLY-21H00179, KAKENHI-PROJECT-20H03399
[Journal Article] Identification of biomarkers to diagnose diseases and find adverse drug reactions by metabolomics2021
- Author(s)
  Saigusa Daisuke、Matsukawa Naomi、Hishinuma Eiji、Koshiba Seizo
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 37 Pages: 100373-100373
- DOI
  10.1016/j.dmpk.2020.11.008
- NAID
  210000172800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-17K07298
[Journal Article] Identification of novel biomarkers of hepatocellular carcinoma by high-definition mass spectrometry: Ultrahigh-performance liquid chromatography quadrupole time-of-flight mass spectrometry and desorption electrospray ionization mass spectrometry imaging2020
- Author(s)
  Nagai, K. et al. Koshiba S. et al. Tomioka Y.（合計１７名、本研究者は１４番目）
- Journal Title
  
  Rapid Commun Mass Spectrom.
  
  Volume: 34 Issue: S1
- DOI
  10.1002/rcm.8551
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-18K06651
[Journal Article] Value of global metabolomics in association with diagnosis and clinicopathological factors of renal cell carcinoma2019
- Author(s)
  Sato, T. （途中略）,Koshiba, S., （途中略）, Arai, Y.（合計１５名、本研究者は１３番目）
- Journal Title
  
  Int. J. Cancer
  
  Volume: 145 Issue: 2 Pages: 484
- DOI
  10.1002/ijc.32115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-18K16683, KAKENHI-PROJECT-17K07210
[Journal Article] Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model2019
- Author(s)
  Uranbileg B, Ito N, Kurano M, Saigusa D, Saito R, Uruno A, Kano K, Ikeda H, Yamada Y, Sumitani M, Sekiguchi M, Aoki J, Yatomi Y.
- Journal Title
  
  Scientific reports
  
  Volume: 9 Issue: 1 Pages: 16578-16578
- DOI
  10.1038/s41598-019-52999-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-17K11103, KAKENHI-PROJECT-16KK0195
[Journal Article] Measurement of the Spatial Distribution of S1P in Small Quantities of Tissues: Development and Application of a Highly Sensitive LC-MS/MS Method Combined with Laser Microdissection2019
- Author(s)
  Wang Jiao、Kano Kuniyuki、Saigusa Daisuke、Aoki Junken
- Journal Title
  
  Mass Spectrometry
  
  Volume: 8 Issue: 1 Pages: A0072-A0072
- DOI
  10.5702/massspectrometry.A0072
- NAID
  130007594456
- ISSN
  2186-5116, 2187-137X
- Year and Date
  2019-02-14
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08233
[Journal Article] Conductive Adhesive Film Expands the Utility of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging2019
- Author(s)
  Saigusa D, Saito R, Kawamoto K, Uruno A, Kano K, Aoki J, Yamamoto M, Kawamoto T.
- Journal Title
  
  Anal Chem
  
  Volume: 91 Issue: 14 Pages: 8979
- DOI
  10.1021/acs.analchem.9b01159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-16KK0195
[Journal Article] Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation2018
- Author(s)
  Watanabe Takashi、Saito Takahiro、Rico Evelyn Marie Gutierrez、Hishinuma Eiji、Kumondai Masaki、Maekawa Masamitsu、Oda Akifumi、Saigusa Daisuke、Saito Sakae、Yasuda Jun、Nagasaki Masao、Minegishi Naoko、Yamamoto Masayuki、Yamaguchi Hiroaki、Mano Nariyasu、Hirasawa Noriyasu、Hiratsuka Masahiro
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 156 Pages: 420
- DOI
  10.1016/j.bcp.2018.09.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-17K08257, KAKENHI-PROJECT-18K06742, KAKENHI-PROJECT-15K09464
[Journal Article] Impact of the oral adsorbent AST-120 on organ-specific accumulation of uremic toxins: LC-MS/MS and MS imaging techniques2018
- Author(s)
  Emiko Sato, Daisuke Saigusa, Eikan Mishima, Taeko Uchida, Daisuke Miura, Tomomi Morikawa-Ichinose, Kiyomi Kisu, Akiyo Sekimoto, Ritsumi Saito, Yuji Oe, Yotaro Matsumoto, Yoshihisa Tomioka, Takefumi Mori, Nobuyuki Takahashi, Hirosi Sato, Takaaki Abe, Toshimitsu Niwa, and Sadayosi Ito
- Journal Title
  
  Toxins
  
  Volume: 10 Issue: 1 Pages: 19-33
- DOI
  10.3390/toxins10010019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09599, KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-17K09682, KAKENHI-PROJECT-26713020, KAKENHI-PROJECT-15H04834, KAKENHI-PROJECT-16J03192, KAKENHI-PROJECT-16J40073, KAKENHI-PROJECT-16K19474
[Journal Article] Intracellular S1P Levels Dictate Fate of Different Regions of the Hippocampus following Transient Global Cerebral Ischemia2018
- Author(s)
  Rashad S, Niizuma K, Saigusa D, Han X, Sato-Maeda M, Saito R, Uruno A, Fujimura M, Ikawa S, Yamamoto M, Tominaga T.
- Journal Title
  
  Neuroscience
  
  Volume: 384 Pages: 188
- DOI
  10.1016/j.neuroscience.2018.05.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K07152, KAKENHI-PROJECT-17K08233
[Journal Article] Lactate dehydrogenase C is required for the protein expression of a sperm-specific isoform of lactate dehydrogenase A2018
- Author(s)
  Dodo Mina、Kitamura Hiroshi、Shima Hiroki、Saigusa Daisuke、Wati Sisca Meida、Ota Nao、Katsuoka Fumiki、Chiba Hatsune、Okae Hiroaki、Arima Takahiro、Igarashi Kazuhiko、Koseki Takeyoshi、Sekine Hiroki、Motohashi Hozumi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 165 Issue: 4 Pages: 323
- DOI
  10.1093/jb/mvy108
- NAID
  40021893390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-17K08233, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K15591, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-17H04335, KAKENHI-PROJECT-17K08618
[Journal Article] Functional characterization of 50 CYP2D6 allelic variants by assessing primaquine 5-hydroxylation2018
- Author(s)
  Saito Takahiro、Gutierrez Rico Evelyn Marie、Kikuchi Aoi、Kaneko Akira、Kumondai Masaki、Akai Fumika、Saigusa Daisuke、Oda Akifumi、Hirasawa Noriyasu、Hiratsuka Masahiro
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 33 Issue: 6 Pages: 250
- DOI
  10.1016/j.dmpk.2018.08.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-17K08257
[Journal Article] Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinuss2018
- Author(s)
 Tachikawa Masanori、Sumiyoshiya Yuna、Saigusa Daisuke、Sasaki Kazunari、Watanabe Michitoshi、Uchida Yasuo、Terasaki Tetsuya
- Journal Title
 
 Drug Metab Dispos
 
 Volume: 46 Issue: 5 Pages: 610
- DOI
 10.1124/dmd.117.079244
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-17K08233
[Journal Article] Metabolomic changes in the mouse retina after optic nerve injury2018
- Author(s)
  Sato K, Saigusa D, Saito R, Fujioka A, Nakagawa Y, Nishiguchi KM, Kokubun T, Motoike IN, Maruyama K, Omodaka K, Shiga Y, Uruno A, Koshiba S, Yamamoto M, Nakazawa T.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 11930-11930
- DOI
  10.1038/s41598-018-30464-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-17K11475, KAKENHI-PROJECT-17K16958
[Journal Article] Metabolomic Analysis of Mouse Brain after a Transient Middle Cerebral Artery Occlusion by Mass Spectrometry Imaging2018
- Author(s)
  Abe T, Niizuma K, Kanoke A, Saigusa D, Saito R, Uruno A, Fujimura M, Yamamoto M, Tominaga T.
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 58 Issue: 9 Pages: 384-392
- DOI
  10.2176/nmc.oa.2018-0054
- NAID
  130007484209
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K08233
[Journal Article] Evidence Suggests Sphingosine 1-Phosphate Might Be Actively Generated, Degraded, and Transported to Extracellular Spaces With Increased S1P 2 and S1P 3 Expression in Colon Cancer2017
- Author(s)
 Uranbileg B, Nishikawa T, Ikeda H, Kurano M, Sato M, Saigusa D, Aoki J, Watanabe T, Yatomi Y.
- Journal Title
 
 Clin Colorectal Cancer.
 
 Volume: 17 Issue: 2 Pages: 30369-9
- DOI
 10.1016/j.clcc.2017.11.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-16K09343, KAKENHI-PROJECT-17K08233, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906
[Journal Article] Autotaxin–lysophosphatidic acid–LPA3 signaling at the embryo-epithelial boundary controls decidualization pathways2017
- Author(s)
 Aikawa Shizu、Kano Kuniyuki、Inoue Asuka、Wang Jiao、Saigusa Daisuke、Nagamatsu Takeshi、Hirota Yasushi、Fujii Tomoyuki、Tsuchiya Soken、Taketomi Yoshitaka、Sugimoto Yukihiko、Murakami Makoto、Arita Makoto、Kurano Makoto、Ikeda Hitoshi、Yatomi Yutaka、Chun Jerold、Aoki Junken
- Journal Title
 
 EMBO J
 
 Volume: 36 Issue: 14 Pages: 2146
- DOI
 10.15252/embj.201696290
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-17K08233, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-16H02613, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-15H04979, KAKENHI-PROJECT-16H04679, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-16K15122, KAKENHI-PROJECT-16K15700, KAKENHI-PROJECT-16K15701, KAKENHI-PROJECT-26670030
[Journal Article] Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence2016
- Author(s)
  Uranbileg B, Ikeda H, Kurano M, Enooku K, Sato M, Saigusa D, Aoki J, Ishizawa T, Hasegawa K, Kokudo N, Yatomi Y.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 2 Pages: e0149462-e0149462
- DOI
  10.1371/journal.pone.0149462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15378, KAKENHI-PROJECT-15K18842, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-25253040, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-16K09343
[Journal Article] Establishment of protocols for global metabolomics by LC-MS for biomarker discovery2016
- Author(s)
  Saigusa D, Okamura Y, Motoike IN, Katoh Y, Kurosawa Y, Saijyo R, Koshiba S, Yasuda J, Motohashi H, Sugawara J, Tanabe O, Kinoshita K, Yamamoto M
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 8 Pages: e0160555-e0160555
- DOI
  10.1371/journal.pone.0160555
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-15K18842, KAKENHI-PROJECT-26440018
[Journal Article] Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human2016
- Author(s)
  Sato M, Ikeda H, Uranbileg B, Kurano M, Saigusa D, Aoki J, Maki H, Kudo H, Hasegawa K, Kokudo N, Yatomi Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 32119-32119
- DOI
  10.1038/srep32119
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-15K18842, KAKENHI-PROJECT-16K09343
[Journal Article] A novel and sensitive assay for heme oxygenase activity2015
- Author(s)
  Iwamori S, Sato E, Saigusa D, Yoshinari K, Ito S, Sato H, and Takahashi N
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 309 Issue: 7 Pages: F667-F671
- DOI
  10.1152/ajprenal.00210.2015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18842
[Journal Article] Mitochonic Acid 5 (MA-5), a Derivative of the Plant Hormone Indole-3-Acetic Acid, Improves Survival of Fibroblasts from Patients with Mitochondrial Diseases2015
- Author(s)
  Suzuki T, Yamaguchi H, Kikusato M, Matsuhashi T, Matsuo A, Sato T, Oba Y, Watanabe S, Minaki D, Saigusa D, Shimbo H, Mori N, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Yuri A, Kikuchi K, Toyohara T, Suzuki C, Kohzuki M, Anzai J, Mano N, Kure S, Yanagisawa T, Tomioka Y, Toyomizu M, Ito S, Osaka H, Hayashi K, Abe T
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 236 Issue: 3 Pages: 225-232
- DOI
  10.1620/tjem.236.225
- NAID
  130005083526
- ISSN
  0040-8727, 1349-3329
- URL
  https://pure.teikyo.jp/en/publications/f34848a7-3f52-481e-850d-fae28c8f317e
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460331, KAKENHI-PROJECT-15K18842, KAKENHI-PROJECT-24590311, KAKENHI-PROJECT-26670070, KAKENHI-PROJECT-26860624, KAKENHI-PROJECT-26293031, KAKENHI-PROJECT-26305007
[Journal Article] Functional characterization of 10 CYP4A11 allelic variants to evaluate the effect of genotype on arachidonic acid ω-hydroxylation2015
- Author(s)
  Saito T, Honda M, Saigusa D, Suzuiki N, Tomioka Y, Hirasawa N, Hiratsuka M.
- Journal Title
  
  Drug Metabal.& Pharmacokin
  
  Volume: 30 Issue: 1 Pages: 119
- DOI
  10.1016/j.dmpk.2014.09.001
- NAID
  50014415989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860021
[Journal Article] Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MS2014
- Author(s)
  Okudaira M, Inoue A, Shuto A, Nakanaga K, Kano K, Makide K, Saigusa D, Tomioka Y, Aoki J.
- Journal Title
  
  J. Lipid Res.
  
  Volume: 55 Issue: 10 Pages: 2178
- DOI
  10.1194/jlr.d048439
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-25293010, KAKENHI-PROJECT-25430135, KAKENHI-PROJECT-25860021, KAKENHI-PROJECT-26670021
[Journal Article] Simultaneous Quantification of Sphingolipids in Small Quantities of Liver by LC-MS/MS2014
- Author(s)
  Okudaira M, Inoue A, Shuto A, Nakanaga K, Kano K, Makide K, Saigusa D, Tomioka Y and Aoki J
- Journal Title
  
  Mass Spectrometry
  
  Volume: 3 Issue: Special_Issue_3 Pages: S0046-S0046
- DOI
  10.5702/massspectrometry.S0046
- NAID
  130004972834
- ISSN
  2186-5116, 2187-137X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860021
[Journal Article] Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo2014
- Author(s)
  Nakanaga K, Hama K, Kano K, Sato T, Yukiura H, Inoue A, Saigusa D, Tokuyama H, Tomioka Y, Nishina H, Kawahara A, Aoki J
- Journal Title
  
  J. Biochem
  
  Volume: 155 Issue: 4 Pages: 235
- DOI
  10.1093/jb/mvt114
- NAID
  40020035029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J05211, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-24770114, KAKENHI-PROJECT-24790064, KAKENHI-PROJECT-24890014, KAKENHI-PROJECT-25430135, KAKENHI-PROJECT-25860021, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26293012, KAKENHI-PROJECT-26640064
[Journal Article] Indoxyl Sulfate Down-Regulates SLCO4C1 Transporter through Up-Regulation of GATA32013
- Author(s)
  Akiyama Y, Kikuchi K, Saigusa D, Suzuki T, Takeuchi Y, Mishima E, Yamamoto Y, Ishida A, Sugawara D, Jinno D, Shima H, Toyohara T, Suzuki C, Souma T, Moriguchi T, Tomioka Y, Ito S, Abe T.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 7 Pages: e66518-e66518
- DOI
  10.1371/journal.pone.0066518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07924, KAKENHI-PROJECT-23390033, KAKENHI-PROJECT-24590177, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659062, KAKENHI-PROJECT-24890013, KAKENHI-PROJECT-25430135, KAKENHI-PROJECT-25860021
[Journal Article] Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function2013
- Author(s)
  Nakamura A, Ebina-Shibuya R, Itoh-Nakadai A, Muto A, Shima H, Saigusa D, Aoki J, Ebina M, Nukiwa T, Igarashi K.
- Journal Title
  
  J Exp Med.
  
  Volume: 210 Issue: 11 Pages: 2191
- DOI
  10.1084/jem.20130028
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116004, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-25860021
[Patent] イオン化法及び質量分析法2019
- Inventor(s)
  三枝大輔
- Industrial Property Rights Holder
  三枝大輔
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-066619
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K08233
[Patent] 視神経障害の診断用バイオマーカー2018
- Inventor(s)
  中澤徹、佐藤孝太、三枝大輔
- Industrial Property Rights Holder
  中澤徹、佐藤孝太、三枝大輔
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H04349
[Patent] 視神経障害の診断用バイオマーカー2018
- Inventor(s)
  中澤徹、佐藤孝太、三枝大輔
- Industrial Property Rights Holder
  中澤徹、佐藤孝太、三枝大輔
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H04349
[Presentation] ヒト前房水の細胞外小胞由来リピドームを標的とした緑内障早期診断マーカー探索2024
- Author(s)
  西原詩織、佐藤孝太、藤岡周、横山悠、福内友子、山岡法子、中澤徹、三枝大輔
- Organizer
  日本薬学会第144回年会
- Data Source
  KAKENHI-PROJECT-23K27316
[Presentation] 小児てんかん患者の脳脊髄液に含まれる細胞外小胞リピドーム解析によるバイオマーカー探索2024
- Author(s)
  石井亜里紗、福内友子、山岡法子、秋山倫之、三枝大輔
- Organizer
  日本薬学会第144回年会
- Data Source
  KAKENHI-PROJECT-23K27316
[Presentation] アンチ・ドーピングに資するバダデュスタット投与マウスを用いたサロゲートマーカー探索研究2024
- Author(s)
  大橋智輝、中井琢、福内友子、山岡法子、小柴生造、山本雅之、鈴木教郎、三枝大輔
- Organizer
  日本薬学会第144回年会
- Data Source
  KAKENHI-PROJECT-23K27316
[Presentation] 血漿およびエクソソーム由来代謝物分析手法開発と肺腺癌マーカー探索への応用2023
- Author(s)
  三枝大輔、本田健、岩崎裕子、植田幸嗣、福内友子、山岡法子、副島研造、岸一馬、大熊裕介、富樫亮、松谷哲行、関順彦
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] GC-MS/MSによるダプロデュスタット服用マウスの血漿および尿中メタボローム解析2023
- Author(s)
  内田新菜、中井琢、福内友子、山岡法子、小柴生造、山本雅之、鈴木教郎、三枝大輔
- Organizer
  日本薬学会第144回年会
- Data Source
  KAKENHI-PROJECT-23K27316
[Presentation] 肺腺癌患者血漿由来細胞外小胞を対象としたメタボローム解析2023
- Author(s)
  岩崎裕子、本田健、植田幸嗣、福内友子、山岡法子、菱沼英史、松川直美、富樫亮、松谷哲行、関順彦、三枝大輔
- Organizer
  第10回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27316
[Presentation] LC/MSによる肺腺がん患者血漿由来細胞外小胞を用いたバイオマーカー探索2023
- Author(s)
  岩崎裕子、本田健、植田幸嗣、福内友子、山岡法子、菱沼英史、松川直美、富樫亮、松谷哲行、関順彦、三枝大輔
- Organizer
  第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K27316
[Presentation] イオンモビリティ搭載飛行時間MSによるスフィンゴ糖脂質異性体分離分析法開発2023
- Author(s)
  井上莉那、可野邦行、福内友子、山岡法子、青木淳賢、三枝大輔
- Organizer
  第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K27316
[Presentation] 宇宙環境における酸化ストレスがもたらす生体内脂質変動解析2022
- Author(s)
  小池海斗、三枝大輔、宇留野晃、鈴木隆史、福内友子、山岡法子、芝大、山本雅之
- Organizer
  第70回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] UHPLC-FTMSによるヒト前房水を用いた緑内障バイオマーカー探索研究2022
- Author(s)
  小暮瑞穂、佐藤孝太、藤岡周、國分太貴、吉田真彰、横山悠、福内友子、山岡法子、中澤徹、三枝大輔
- Organizer
  第70回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] Lipidomic Profiling in the Large-Scale Cohort for Biomarker Discovery and the Importance of Separation Science2022
- Author(s)
  Daisuke Saigusa
- Organizer
  Gordon Research Conference, Lipidomics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] 生体内メタボローム解析技術開発と疾患バイオマーカー探索研究への応用2022
- Author(s)
  三枝大輔
- Organizer
  第47回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] 疾患関連リゾリン脂質の高精密定量を目的とした分離分析系の開発について2021
- Author(s)
  三枝大輔、青木淳賢
- Organizer
  第32回クロマトグラフィー科学会議
- Invited
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] 質量分析イメージングの高感度検出に向けた研究2021
- Author(s)
  三枝大輔、青木淳賢
- Organizer
  第74回イオン反応研究部会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] Addressing accuracy of reference values in a large-scale cohort by MS-based metabolomics2021
- Author(s)
  Daisuke Saigusa
- Organizer
  VPAP
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] Evaluation for quantified values of lipidomic profiling in a large-scale cohort2021
- Author(s)
  Daisuke Saigusa
- Organizer
  iSLS10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] 質量分析イメージングによる疾患バイオマーカーの機能評価に関する研究2021
- Author(s)
  三枝大輔
- Organizer
  日本薬学会第141年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] The utility of conductive adhesive film for the distribution analysis of small molecule by MALDI－MSI2020
- Author(s)
  Daisuke Saigusa
- Organizer
  24h-IMSI
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03374
[Presentation] MSイメージングによる疾患モデル動物解析と創薬への応用性について2019
- Author(s)
  三枝大輔、齋藤律水、宇留野晃
- Organizer
  第32回バイオメディカル分析科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] 疾患モデル動物のメタボローム組織分布解析による疾患発症リスク因子の同定2019
- Author(s)
  三枝大輔、齋藤律水、宇留野晃
- Organizer
  第92回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] 質量分析計によるヒト肝がん浸潤バイオマーカー探索2019
- Author(s)
  三枝大輔・永井滉士・Baasanjav Uranbileg・蔵野信・池田均・矢冨裕・富岡佳久・青木淳賢
- Organizer
  第13回日本緩和医療薬学会年会
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] Impact of the DIUTHAME for Distribution Analysis of Metabolites on Biological Tissues by DESI-MSI2019
- Author(s)
  Daisuke Saigusa, Masahiro Kotani, Takayuki Ohmura
- Organizer
  ASMS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] MALDI-MSI分析における導電性粘着フィルムの生体組織切片作成への有用性について2019
- Author(s)
  三枝大輔、齋藤律水、川本孔明、宇留野晃、可野邦行、青木淳賢、山本雅之、川本忠文
- Organizer
  第44回医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] 疾患モデルマウスにおける質量分析メタボローム解析が切り拓く新たな創薬の道筋2019
- Author(s)
  三枝大輔、齋藤律水、宇留野晃
- Organizer
  日本プロテオーム学会2019年大会・第70回日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] Metabolic Profiling of Hepatocellular Carcinoma by High-Definition Mass Spectrometry2019
- Author(s)
  Daisuke Saigusa
- Organizer
  Tohoku Forum for Creativity Thematic Program 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] High-Definition Mass Spectrometryによるヒト肝がん組織のメタボローム解析2018
- Author(s)
  三枝大輔・永井滉士・Baasanjav Uranbileg・蔵野信・長谷川潔・國土典宏・池田均・矢冨裕・富岡佳久・青木淳賢
- Organizer
  日本質量分析学会・日本プロテオーム学会2018年合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] Oral alkali supplementation to reduce uremic toxin in early stage CKD patients.2018
- Author(s)
  Michiaki Abe, Daisuke Saigusa, Seizo Koshiba, Fumitoshi Satoh, Hiroshi Sato, Tadashi Ishii, Sadayoshi Ito and CKOALA study group.
- Organizer
  ISN Frontiers Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08487
[Presentation] Metabolic profiling of Hepatocellular Carcinoma by High-Definition Mass Spectrometry2018
- Author(s)
  D.Saigusa, K. Nagai, B. Uranbileg, M. Kurano, H. Ikeda, Y. Yatomi, Y. Tomioka, J. Aoki
- Organizer
  Metabolomics 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] 標準化合物なしで正確な相対定量を行うための考え方2018
- Author(s)
  三枝大輔
- Organizer
  第160回質量分析関西談話会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] Metabolic Profiling of Clinical and Cohort Studies for Searching Biomarkers2018
- Author(s)
  D. Saigusa, I.N. Motoike, S. Koshiba
- Organizer
  2018 Mass Spectrometry for Clinical Diagnosis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] Mass Spectrometry Imaging による生体内メタボローム組織分布解析2018
- Author(s)
  三枝大輔
- Organizer
  第40回生体膜と薬物の相互作用シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] High-Definition Mass Spectrometryによるヒト肝がん組織メタボローム解析2018
- Author(s)
  三枝大輔
- Organizer
  第5回包括的緩和医療科学学術研究会、第6回 Tokyo 疼痛緩和次世代研究会合同研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] MSイメージング技術のメタボローム解析への応用について2018
- Author(s)
  三枝大輔
- Organizer
  質量分析イメージングセミナー 2018
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] 生体内脂質分子を高感度且つ網羅的に定量するためのノウハウ2018
- Author(s)
  三枝大輔
- Organizer
  第60回日本脂質生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] Oral alkali supplementation to reduce uremic toxin in early stage CKD patients2018
- Author(s)
  Abe M, Saigusa D, Koshiba S, Tanabe O, Satoh F, Sato H, Ishii T, Ito S and CKOALA study group
- Organizer
  ISN Frontiers meetings
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08487
[Presentation] High-Definition Mass Spectrometryによるヒト肝がん組織のメタボロミクス解析2018
- Author(s)
  三枝大輔・永井滉士・Baasanjav Uranbileg・蔵野信・長谷川潔・國土典宏・池田均・矢冨裕・富岡佳久・青木淳賢
- Organizer
  第43回医用マススペクトル学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] 経口アルカリ性化剤により薬物的血液浄化される尿毒症物質の検討2017
- Author(s)
  阿部倫明,三枝大輔,小柴生造,鈴木洋一,田邊修,安田純,佐藤文俊,工藤正孝,佐藤博,森本玲,中道崇,小川晋,清元秀泰,三木俊,高山真,宮崎真理子,石井正,伊藤貞嘉,CKOALA 研究グループ
- Organizer
  第60回日本腎臓学会学術総会
- Place of Presentation
  仙台，仙台国際センター
- Year and Date
  2017-05-26
- Data Source
  KAKENHI-PROJECT-16K08487
[Presentation] Establishment of Normalization Protocol for Global Metabolomics in a Large-scale Study Using Mass Spectrometry2017
- Author(s)
  D.Saigusa, I.N.Motoike, S.Koshiba
- Organizer
  Metabolomics2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] High-Definition Mass Spectrometryによるヒト肝がん組織メタボローム解析2017
- Author(s)
  三枝大輔、永井滉士、Baasanjav Uranbileg、蔵野信、池田均、矢冨裕、富岡佳久、青木淳賢
- Organizer
  第10回メタボロームシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] 質量分析計を用いる大規模メタボローム解析におけるデータ補正について2017
- Author(s)
  三枝大輔、元池育子、小柴生造
- Organizer
  第65回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] DART-MS によるリアルタイムメタボロミクスの基盤技術開発2017
- Author(s)
  三枝大輔
- Organizer
  第42回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] 大規模コホートメタボロームリファレンスの薬物代謝解析への活用2017
- Author(s)
  三枝大輔
- Organizer
  日本薬物動態学会第32回年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] メタボロミクス解析を用いたサルコイドーシスの活動性予測バイオマーカーの探索2017
- Author(s)
  蒲生俊一、玉田　勉、村上康司、三枝大輔、元池育子、有竹秀美、奈良正之、村松聡士、杉浦久敏、一ノ瀬正和
- Organizer
  第37回日本サルコイドーシス/肉芽腫性疾患学会総会
- Data Source
  KAKENHI-PROJECT-15K19410
[Presentation] 経口アルカリ性化剤により薬物的血液浄化される尿毒症物質の検討2017
- Author(s)
  阿部倫明，三枝大輔，小柴生造，鈴木洋一，田邊修，安田純，佐藤文俊，工藤正孝，佐藤博，森本玲，中道崇，小川晋，清元秀泰，三木俊，高山真，宮崎真理子，石井正，伊藤貞嘉，CKOALA 研究グループ
- Organizer
  第60回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-16K08487
[Presentation] Oral alkali supplementation to reduce uremic toxin in early stage CKD patients.2017
- Author(s)
  Michiaki Abe, Daisuke Saigusa, Tomokazu Souma, Hiroshi Sato, Sadayoshi Ito and CKOALA study group.
- Organizer
  Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08487
[Presentation] Omics Research in a Large-scale Cohort by MS2017
- Author(s)
  Daisuke Saigusa
- Organizer
  BIT's 5th Annual Conference of AnalytiX 2017
- Place of Presentation
  Hilton Fukuoka Sea Hawk（福岡県・福岡市）
- Year and Date
  2017-03-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18842
[Presentation] 質量分析計を用いる生体内スフィンゴ脂質の安定性評価と臨床領域への応用2016
- Author(s)
  三枝大輔、王嬌、可野邦行、B.Uranbileg、蔵野信、池田均、矢冨裕、青木淳賢
- Organizer
  第64回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府・吹田市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K18842
[Presentation] 大規模メタボロームデータの多層オミクス解析への応用2016
- Author(s)
  三枝大輔、元池育子、小柴生造
- Organizer
  第10回メタボロームシンポジウム
- Place of Presentation
  鶴岡メタボロームキャンパス（山形県・鶴岡市）
- Year and Date
  2016-10-19
- Data Source
  KAKENHI-PROJECT-15K18842
[Presentation] Transomics analysis in a large-scale cohort study2016
- Author(s)
  三枝大輔
- Organizer
  日本プロテオーム学会2016年大会
- Place of Presentation
  北里大学薬学部白金キャンパス（東京都・港区）
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K18842
[Presentation] Global Metabolomic Analysis by UPLC-TOF-MS for Identification of Predictive and Prognostic Biomarkers for Obstetric Complications2015
- Author(s)
  Daisuke Saigusa, Junichi Sugawara, Mitsuyo Matsumoto, Yasutake Katoh, Ryu Yamashita, Yasuhiro Kurosawa, Jun Yasuda, Osamu Tanabe, Masayuki Yamamoto
- Organizer
  8th International DIP Symposium on Diabetes, Hypertension, Metabolic Syndrome & Pregnancy
- Place of Presentation
  Berlin, Germany
- Year and Date
  2015-04-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18842
[Presentation] 臨床メタボローム解析による疾患予防マーカー探索2015
- Author(s)
  三枝大輔
- Organizer
  第36回グアニジノ化合物研究会
- Place of Presentation
  東北大学大学院薬学研究科、宮城県仙台市
- Year and Date
  2015-08-08
- Data Source
  KAKENHI-PROJECT-15K18842
[Presentation] Development of Protocol for Global Metabolomics in Clinical and Cohort Study by LC-MS2015
- Author(s)
  Daisuke Saigusa, Junichi Sugawara, Mitsuyo Matsumoto, Yasutake Katoh, Ryu Yamashita, Yasuhiro Kurosawa, Jun Yasuda, Masayuki Yamamoto, Osamu Tanabe
- Organizer
  Metabolomics 2015
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2015-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18842
[Presentation] 臨床領域における質量分析計を基盤としたメタボローム解析の発展2015
- Author(s)
  三枝大輔
- Organizer
  第63回質量分析総合討論会
- Place of Presentation
  つくば国際会議場、茨城県つくば市
- Year and Date
  2015-06-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K18842
[Presentation] 大規模コホートオミクス解析による疾患予防マーカー探索2015
- Author(s)
  三枝大輔
- Organizer
  第40回日本医用マススペクトル学会
- Place of Presentation
  アクトシティ浜松、静岡県浜松市
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K18842
[Presentation] 日本人多層オミックス参照パネル公開2015
- Author(s)
  小柴生造、加藤恭丈、三枝大輔、元池育子、城田松之、斎藤智、田邉修、安田純、木下賢吾、山本雅之
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会年会
- Place of Presentation
  神戸ポートアイランド、兵庫県・神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460351
[Presentation] リコカルコンＡのCOX-1活性抑制メカニズムの解明2014
- Author(s)
  菅原大貴、田代　匠、三枝大輔、塚本宏樹、奥田亜沙、小原祐太郎、鈴木直人、富岡佳久
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] LC/MSによる分離技術を基盤とした高感度メタボローム解析手法の開発と臨床応用に関する研究2014
- Author(s)
  三枝大輔
- Organizer
  第41回BMSコンファレンス
- Place of Presentation
  能登ロイヤルホテル（石川県羽咋郡）
- Invited
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] 抗1-methyladenosine抗体反応性分子の同定を目的としたtRNA分子種の解析法に関する研究2014
- Author(s)
  津久井佑梨、陣野大輔、三島英喚、鈴木直人、塚本宏樹、三枝大輔、伊藤邦彦、阿部高明、富岡佳久
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] LC-MS/MS による生体試料を用いた超高感度標的リピドミクス解析手法の構築2014
- Author(s)
  三枝大輔、奥平倫世、井上飛鳥、青木淳賢、五十嵐和彦
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府吹田市）
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] 11種のCYP4A11および3種のCYP4F2遺伝子多型バリアントにおける酵素活性変化2014
- Author(s)
  齊藤雄大、三枝大輔、鈴木直人、富岡佳久、平澤典保、平塚真弘
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] LysoPSの検出系の確立と生体内におけるLysoPSの検出2013
- Author(s)
  奥平倫世、井上飛鳥、三枝大輔、富岡佳久、巻出久美子、青木淳賢
- Organizer
  日本脂質生化学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] LC/MSによる臨床検体のハイスループット解析-非標的及び標的メタボローム解析手法構築-2013
- Author(s)
  三枝大輔
- Organizer
  第8回メタボロームシンポジウム
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] TOHOKU MEDICAL MEGABANK PROJECT AND TARGETED METABOLOMICS2013
- Author(s)
  Daisuke Saigusa
- Organizer
  Translating Omics Science into Clinical Applications conference (TOSCA‘13)
- Place of Presentation
  香港、中国
- Invited
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] 新規腎障害マーカーとしての１－メチルアデノシンの検討
- Author(s)
  陣野大輔、鈴木直人、津久井佑梨、三枝大輔、三島英換、鈴木千登世、塚本宏樹、阿部高明、富岡佳久
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] LC-MS/MSによる生体試料を用いた超高感度標的リピドミクス解析手法の構築
- Author(s)
  三枝大輔・奥平倫世・井上飛鳥・青木淳賢・五十嵐和彦
- Organizer
  第62回質量分析総合討論会
- Place of Presentation
  大阪　ホテル阪急エクスポパーク
- Year and Date
  2014-05-14 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] LC-MSによる微量組織切片中リゾリン脂質の分析
- Author(s)
  三枝大輔、奥平倫世、Wang Jiao、可野邦行、Baassanjav Uranbileg、蔵野信、池田均、矢富裕、青木淳賢、本橋ほづみ
- Organizer
  日本薬学会　第135年会
- Place of Presentation
  神戸　神戸学院大学
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] TOHOKU MEDICAL MEGABANK PROJECT AND TARGETED METABOLOMICS
- Author(s)
  三枝大輔、青木淳賢、富岡佳久、五十嵐和彦、阿部高明
- Organizer
  第34回グアニジノ化合物研究会
- Place of Presentation
  全国町村会館（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-25860021
[Presentation] Simultaneous quantification of sphingolipids in small quantities of tissue by LC-MS/MS
- Author(s)
  Daisuke Saigusa, Michiyo Okudaira, Jiao Wang, Kuniyuki Kano, Makoto Kurano, Baasanjav Uranbileg, Hitoshi Ikeda, Yutaka Yatomi, Hozumi Motohashi, and Junken Aoki
- Organizer
  PLM2015
- Place of Presentation
  Tokyo Keio Plaza Hotel
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-25860021

1. 可野邦行 (50636404)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. IGARASHI Kazuhiko (00250738)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Nakazawa Toru (30361075)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Uchida Yasuo (70583590)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 元池育子 (70347178)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 松本洋太郎 (90420041)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 佐藤孝太 (50732327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KATOH Yasutake (40397914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. MORITA Masanobu (10519094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAGASHIMA Takeshi (80443000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MATSUMOTO Mitsuyo (80400448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Furukawa Yoshihiro (00544107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Abe Michiaki (40400246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
14. MATSUI Miki (00455784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Muramatsu Soshi (30732549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. Yokoyama Yu (00597312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 中村智樹 (20260721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 宇留野晃 (90396474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 小柴生造 (70332301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. 張替秀郎 (50302146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 水野忠快 (90736050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 國分太貴 (30646443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 矢花武史 (30725213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 津田聡 (60791093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 前川重人 (80625294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 本多敦子 (40467072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 和泉自泰 (70622166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 青木順 (90452424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. 佐藤恵美子 (20466543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 吉田舞 (20778469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 山越聖子 (50868099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 宮崎真理子 (60594695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 田中哲洋 (90508079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. Saito Ritsumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. Shoji Mutsumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. MURAKAMI KOJI

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
37. GAMO SYUNICHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
38. ARITAKE HIDEMI

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
39. 徳永英樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 島田宗昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 重田昌吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saigusa Daisuke 三枝 大輔

SAIGUSA Daisuke 三枝 大輔

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投影型MSイメージング法による脂質ラフト含有スフィンゴ脂質の可視化技術開発Principal Investigator

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Distribution analysis of S1P on tissue sections by high resolution MS imagingPrincipal Investigator

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Development of tree-dimensional MS imaging for sphingolipidsPrincipal Investigator

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Development of a method for distribution analysis of sphingolipids in tissue by mass spectrometryPrincipal Investigator

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Saigusa Daisuke 三枝大輔

SAIGUSA Daisuke 三枝大輔