NAGAE Takayuki 永江峰幸

… Alternative Names

永江峰幸ナガエタカユキ

Nagae Takayuki 永江峰幸

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Researcher Number	90735771
Other IDs	https://orcid.org/0000-0001-7016-5183
Affiliation (Current)	2026: 学習院大学, 理学部, 助教 2026: 東京薬科大学, 生命科学部, 手続きのため
Affiliation (based on the past Project Information) *help	2026: 学習院大学, 理学部, 助教 2025: 東京薬科大学, 薬学部, 助教 2024: 学習院大学, 理学部, 助教 2022 – 2023: 東京薬科大学, 薬学部, 助教 2019 – 2020: 名古屋大学, シンクロトロン光研究センター, 助教 2016 – 2017: 名古屋大学, シンクロトロン光研究センター, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related / Basic Section 43020:Structural biochemistry-related / Structural biochemistry Except Principal Investigator Basic Section 49060:Virology-related / Basic Section 43020:Structural biochemistry-related / Biological Sciences
Keywords	Principal Investigator 生物物理 / 蛋白質 / 蛋白質結晶の分解能向上 / 分解能 / 水和 / 圧力 Except Principal Investigator APOBEC3H / Vif / HIV-1 / 構造解析 … More / X線結晶構造解析 / 核酸結合 / 宿主防御因子 / 結晶構造解析 / 光センサータンパク質 / RcaE / シアノバクテリオクロム / NMR / プロトン化状態 / HIV / 構造 / ユビキチン化 / APOBEC3 / ウイルス / 植物の生殖過程 / 生殖 / 植物の生殖 / イネの生殖 / ジベレリン生合成酵素 / X線構造解析 / 受容体 / ジベレリン / ジベレリンシグナル伝達 / ジベレリン合成酵素 / ジベレリン不活化酵素 / 進化 / GID1 / gibberellin Less

摂動解析による光センサー蛋白質のコンフォメーション探索Principal Investigator
- Principal Investigator
  
  永江峰幸
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Gakushuin University
Hippoシグナル伝達を抑制する転写活性化因子の構造基盤Principal Investigator
- Principal Investigator
  
  永江峰幸
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Structural basis for protonation states of cyanobacterial photosensors
- Principal Investigator
  
  Mishima Masaki
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
APOBEC3Hの核酸結合を基盤とした抗ウイルス活性の分子機序の解明
- Principal Investigator
  
  松岡和弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  National Hospital Organization Nagoya Medical Center
The mechanism of complex formation between HIV-1 Vif and host factor APOBEC3
- Principal Investigator
  
  MATSUOKA Kazuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  National Hospital Organization Nagoya Medical Center
Improving diffraction resolution of protein crystal by high pressurePrincipal Investigator
- Principal Investigator
  
  Nagae Takayuki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nagoya University
Roles of phytohormone in plant reproduction
- Principal Investigator
  
  Ueguchi-Tanaka Miyako
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University

All 2025 2024 2023 2022 2020 2018 2017 2016

All Journal Article Presentation

[Journal Article] Protonation/deprotonation-driven switch for the redox stability of low-potential [4Fe-4S] ferredoxin2024
- Author(s)
  Wada Kei、Kobayashi Kenji、Era Iori、Isobe Yusuke、Kamimura Taigo、Marukawa Masaki、Nagae Takayuki、Honjo Kazuki、Kaseda Noriko、Motoyama Yumiko、Inoue Kengo、Sugishima Masakazu、Kusaka Katsuhiro、Yano Naomine、Fukuyama Keiichi、Mishima Masaki、Kitagawa Yasutaka、Unno Masaki
- Journal Title
  
  eLife
  
  Volume: 102506 Pages: 102506-102506
- DOI
  10.7554/elife.102506.2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03196, KAKENHI-PLANNED-21H05260, KAKENHI-PUBLICLY-24H02094, KAKENHI-PROJECT-23K23826, KAKENHI-PROJECT-22K05321, KAKENHI-PROJECT-24K09346, KAKENHI-PROJECT-23K17981
[Journal Article] Green/red light-sensing mechanism in the chromatic acclimation photosensor2024
- Author(s)
  Nagae Takayuki、Fujita Yuya、Tsuchida Tatsuya、Kamo Takanari、Seto Ryoka、Hamada Masako、Aoyama Hiroshi、Sato-Tomita Ayana、Fujisawa Tomotsumi、Eki Toshihiko、Miyanoiri Yohei、Ito Yutaka、Soeta Takahiro、Ukaji Yutaka、Unno Masashi、Mishima Masaki、Hirose Yuu
- Journal Title
  
  Science Advances
  
  Volume: 10 Issue: 24
- DOI
  10.1126/sciadv.adn8386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24H02094, KAKENHI-PROJECT-23K23826, KAKENHI-PROJECT-22K05037
[Journal Article] Backbone resonance assignments of the C-terminal thioesterase domain of tyrocidine synthetase C2024
- Author(s)
  Takeda Mitsuhiro、Saito Rino、Konno Sho、Nagae Takayuki、Aoyama Hiroshi、Yoshinaga Sosuke、Terasawa Hiroaki、Taguchi Akihiro、Taniguchi Atsuhiko、Hayashi Yoshio、Mishima Masaki
- Journal Title
  
  Biomolecular NMR Assignments
  
  Volume: - Issue: 1 Pages: 17-21
- DOI
  10.1007/s12104-024-10210-5
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24H02094, KAKENHI-PROJECT-23K23826, KAKENHI-PROJECT-23K27305, KAKENHI-PROJECT-23K06082, KAKENHI-PROJECT-23K14375
[Journal Article] Direct evidence for a deprotonated lysine serving as a H-bond “acceptor” in a photoreceptor protein2024
- Author(s)
  Nagae Takayuki、Takeda Mitsuhiro、Noji Tomoyasu、Saito Keisuke、Aoyama Hiroshi、Miyanoiri Yohei、Ito Yutaka、Kainosho Masatsune、Hirose Yuu、Ishikita Hiroshi、Mishima Masaki
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 121 Issue: 36
- DOI
  10.1073/pnas.2404472121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23H04963, KAKENHI-PUBLICLY-24H02094, KAKENHI-PROJECT-23K23826, KAKENHI-PROJECT-23K27137, KAKENHI-PROJECT-24K01986, KAKENHI-PROJECT-23K06082
[Journal Article] 15N NMRによるシアノバクテリオクロムのプロトン化状態の解析2022
- Author(s)
  永江峰幸、青山洋史、三島正規
- Journal Title
  
  日本核磁気共鳴学会機関誌
  
  Volume: 12 Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23826
[Journal Article] A common allosteric mechanism regulates homeostatic inactivation of auxin and gibberellin2020
- Author(s)
  Takehara Sayaka、Sakuraba Shun、Mikami Bunzo、Yoshida Hideki、Yoshimura Hisako、Itoh Aya、Endo Masaki、Watanabe Nobuhisa、Nagae Takayuki、Matsuoka Makoto、Ueguchi-Tanaka Miyako
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41467-020-16068-0
- Data Source
  KAKENHI-PLANNED-16H06468, KAKENHI-PROJECT-20H03272
[Presentation] 緑赤色光吸収型のシアノバクテリオクロムの構造研究2025
- Author(s)
  石塚美葵、武田光広、永江峰幸、青山洋史、広瀬侑、三島正規
- Organizer
  日本薬学会第145年会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] 光センサータンパク質RcaE全長の構造解析2025
- Author(s)
  髙橋直史，永江峰幸，武田光広，青山洋史，広瀬侑，三島正規
- Organizer
  日本薬学会第145年会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] シアノバクテリア光センサータンパク質における脱プロトン化したフィコシアノビリンのNMR解析2024
- Author(s)
  武田光広、永江峰幸、青山洋史、宮ノ人洋平、広瀬侑　三島正規
- Organizer
  第24回　日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] 光センサータンパク質に含まれる脱プロトン化したフィコシアノビリンの選択的安定同位体標識とNMRシグナルの帰属2024
- Author(s)
  武田光広、永江峰幸、青山洋史、宮ノ入洋平、広瀬侑、三島正規
- Organizer
  第63回ＮＭＲ討論会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] 安定同位体ラベル化5-アミノレブリン酸の合成とNMR解析への展開2024
- Author(s)
  青山洋史、飯塚佑介、永江峰幸、武田光広、広瀬侑　三島正規
- Organizer
  第24回　日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] NMR同位体シフト効果を利用したタンパク質に含まれるリジン残基側鎖アミノ基の脱プロトン化状態の可視化2024
- Author(s)
  武田光広、永江峰幸、青山洋史、宮ノ入洋平、会津貴大、広瀬侑、甲斐荘正恒、伊藤隆、三島正規
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] シアノバクテリアが持つ光センサーRcaEの緑色／赤色光吸収状態の構造解析2024
- Author(s)
  永江峰幸、武田光広、青山洋史、飯塚佑介、宮ノ人洋平、広瀬侑、三島正規
- Organizer
  第24回　日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] 光遺伝学を指向したシアノバクテリオクロムの構造基盤2023
- Author(s)
  永江峰幸、飯塚佑介、青山洋史、宮ノ入洋平、神野智司、伊藤隆、広瀬侑、三島正規
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] タンパク質の側鎖官能基に隣接した 13C に誘起される H/D 同位体シフト効果の大きさに基づいた官能基の脱プロトン化状態の可視化2023
- Author(s)
  武田光広，永江峰幸，野地智康，斉藤圭亮，青山洋史，宮ノ入洋平，会津貴大，広瀬侑，甲斐荘正恒，伊藤隆，石北央，三島正規
- Organizer
  第 62 回 NMR 討論会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] シアノバクテリアの光センサーにおける脱プロトン化した塩基性アミノ酸の観測2022
- Author(s)
  永江峰幸、飯塚佑介、青山洋史、宮ノ入洋平、神野智司、伊藤隆、広瀬侑、三島正規
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] 13Cおよび15N標識5-アミノレブリン酸の合成とNMR解析2022
- Author(s)
  青山洋史、飯塚佑介、永江峰幸、広瀬侑、三島正規
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] X-ray crystallographic study and NMR analyses of protonation state of chromophore of cyanobacterial photoreceptor protein2022
- Author(s)
  飯塚佑介、永江峰幸、青山洋史、伊集院良祐、伊藤隆、広瀬侑、三島正規
- Organizer
  第22回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-23K23826
[Presentation] 高圧結晶構造解析によるサーモライシンの高エネルギー準安定構造の研究2018
- Author(s)
  森一也，永江峰幸，渡邉信久
- Organizer
  第7回名古屋大学シンクロトロン光研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-16K18502
[Presentation] サーモライシンの高圧結晶構造解析2018
- Author(s)
  永江峰幸，森一也，渡邉信久
- Organizer
  第31回日本放射光学会年会
- Data Source
  KAKENHI-PROJECT-16K18502
[Presentation] サーモライシンの高圧結晶構造解析2018
- Author(s)
  永江峰幸，森一也，渡邉信久
- Organizer
  第6回あいちシンクロトロン光センター事業成果発表会
- Data Source
  KAKENHI-PROJECT-16K18502
[Presentation] サーモライシンの高圧結晶構造解析2018
- Author(s)
  森一也，永江峰幸，渡邉信久
- Organizer
  2017年度生物物理中部支部講演会
- Data Source
  KAKENHI-PROJECT-16K18502
[Presentation] 加圧によるタンパク質結晶の結晶性向上2017
- Author(s)
  森一也，永江峰幸，渡邉信久
- Organizer
  第58回高圧討論会
- Data Source
  KAKENHI-PROJECT-16K18502
[Presentation] 加圧による蛋白質結晶の分解能向上2017
- Author(s)
  永江峰幸，森一也，渡邉信久
- Organizer
  第30回日本放射光学会年会
- Data Source
  KAKENHI-PROJECT-16K18502
[Presentation] タンパク質構造解析における高圧力の利用2017
- Author(s)
  森一也，永江峰幸，渡邉信久
- Organizer
  特殊環境微生物セミナー2017
- Data Source
  KAKENHI-PROJECT-16K18502
[Presentation] 加圧による蛋白質結晶の分解能向上2017
- Author(s)
  永江峰幸，森一也，渡邉信久
- Organizer
  日本放射光学会
- Place of Presentation
  神戸芸術センター（兵庫県神戸市）
- Year and Date
  2017-01-07
- Data Source
  KAKENHI-PROJECT-16K18502
[Presentation] 加圧による蛋白質結晶の結晶性向上2016
- Author(s)
  永江峰幸，森一也，渡邉信久
- Organizer
  日本結晶学会
- Place of Presentation
  茨城県立県民文化センター（茨城県水戸市）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-16K18502

1. MATSUOKA Kazuhiro (60617140)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Ueguchi-Tanaka Miyako (70377795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. Mishima Masaki (70346310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
4. 松岡信 (00270992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 渡邉信久 (70212321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 海野昌喜 (10359549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 広瀬侑 (30616230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. 宇梶裕 (80193853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 青山洋史 (40374699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 伊藤昭博 (40391859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 前本佑樹 (90742619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAITO Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 元山祐美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 和田啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 渡辺信久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGAE Takayuki 永江 峰幸

永江 峰幸 ナガエ タカユキ

Nagae Takayuki 永江 峰幸

Research Projects

Research Products

Co-Researchers

摂動解析による光センサー蛋白質のコンフォメーション探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Hippoシグナル伝達を抑制する転写活性化因子の構造基盤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural basis for protonation states of cyanobacterial photosensors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

APOBEC3Hの核酸結合を基盤とした抗ウイルス活性の分子機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of complex formation between HIV-1 Vif and host factor APOBEC3

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Improving diffraction resolution of protein crystal by high pressurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of phytohormone in plant reproduction

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Protonation/deprotonation-driven switch for the redox stability of low-potential [4Fe-4S] ferredoxin2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Green/red light-sensing mechanism in the chromatic acclimation photosensor2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Backbone resonance assignments of the C-terminal thioesterase domain of tyrocidine synthetase C2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Direct evidence for a deprotonated lysine serving as a H-bond “acceptor” in a photoreceptor protein2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 15N NMRによるシアノバクテリオクロムのプロトン化状態の解析2022

Author(s)

Journal Title

Data Source

[Journal Article] A common allosteric mechanism regulates homeostatic inactivation of auxin and gibberellin2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 緑赤色光吸収型のシアノバクテリオクロムの構造研究2025

Author(s)

Organizer

NAGAE Takayuki 永江峰幸

永江峰幸ナガエタカユキ

Nagae Takayuki 永江峰幸

[Presentation] タンパク質の側鎖官能基に隣接した 13C に誘起される H/D 同位体シフト効果の大きさに基づいた官能基の脱プロトン化状態の可視化2023